#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P03427 uniprotkb:Q9BUQ8 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-540096|uniprotkb:B2R600|uniprotkb:O43188|uniprotkb:B4DH15|intact:EBI-2557638|ensembl:ENSP00000310723 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ddx23_human(display_long)|uniprotkb:DEAD box protein 23(gene name synonym)|uniprotkb:100 kDa U5 snRNP-specific protein(gene name synonym)|uniprotkb:U5-100kD(gene name synonym)|uniprotkb:PRP28 homolog(gene name synonym)|uniprotkb:DDX23(gene name)|psi-mi:DDX23(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_004809.2|ensembl:ENSG00000174243(gene)|ensembl:ENST00000308025(transcript)|go:"GO:0000354"(cis assembly of pre-catalytic spliceosome)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9BUQ8|rcsb pdb:3JCR|rcsb pdb:4NHO|rcsb pdb:6AH0|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-34974N|genbank_protein_gi:41327771(identity)|refseq:NP_004809(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:tEDp48akFaCjRBBXB4jtyrAsLQ89606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q5T890 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-3951765|uniprotkb:B2RTP8|uniprotkb:Q49AM9|uniprotkb:Q5T892|uniprotkb:Q9NPM7|ensembl:ENSP00000499371|uniprotkb:A4D997|uniprotkb:Q8N663|uniprotkb:Q8N9D0 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:er6l2_human(display_long)|uniprotkb:ERCC6L2(gene name)|psi-mi:ERCC6L2(display_short)|uniprotkb:C9orf102(gene name synonym)|uniprotkb:DNA repair and recombination protein RAD26-like(gene name synonym)|uniprotkb:RAD26L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_064592.2|ensembl:ENSG00000182150(gene)|ensembl:ENST00000665077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0036297"(interstrand cross-link repair)|refseq:NP_001010895.1|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR002999(Tudor)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR029256|interpro:IPR038718|rcsb pdb:6HQ9|genbank_protein_gi:150172042(identity)|refseq:CAI40281(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:m84Vig2Pyiy4FF+ql18rTX5GBUs9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96QL0 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-8456461|intact:MINT-4934930 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q96ql0_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|refseq:NP_001029025.1|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR000597(Ribosomal protein L3)|genbank_protein_gi:14250148(identity)|refseq:AAH08492(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 14 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:EnPwbNjlPAa+l6qOghPhXP1b8jc9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q5R3I4 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-7289489|intact:MINT-5006270|uniprotkb:Q8WV27|uniprotkb:Q9NWP8|intact:MINT-3046919|ensembl:ENSP00000370419 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ttc38_human(display_long)|uniprotkb:TTC38(gene name)|psi-mi:TTC38(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_060401.2|ensembl:ENSG00000075234(gene)|ensembl:ENST00000381031(transcript)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033891|genbank_protein_gi:119593819(identity)|refseq:EAW73413(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:mint|comment:homomint|comment:This prey was identified in band no. 15 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:sw7pabkvaJL/3xAmYn5NFSGQ68I9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P32298 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-5774453|uniprotkb:Q14725|uniprotkb:Q17RH6|uniprotkb:Q15314|uniprotkb:Q15313|uniprotkb:Q53EQ8|uniprotkb:O00642|uniprotkb:Q13293|uniprotkb:Q15316|uniprotkb:Q13295|uniprotkb:O00641|uniprotkb:Q14453|uniprotkb:Q15315|uniprotkb:Q13294|ensembl:ENSP00000381129 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:grk4_human(display_long)|uniprotkb:GRK4(gene name)|psi-mi:GRK4(display_short)|uniprotkb:G protein-coupled receptor kinase GRK4(gene name synonym)|uniprotkb:GPRK2L(gene name synonym)|uniprotkb:GPRK4(gene name synonym)|uniprotkb:ITI1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001004056.1|refseq:NP_001004057.1|refseq:NP_892027.2|refseq:NP_005298.2|ensembl:ENSG00000125388(gene)|ensembl:ENST00000398052(transcript)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0031623"(receptor internalization)|go:"GO:0043025"(neuronal cell body)|go:"GO:0050254"(rhodopsin kinase activity)|go:"GO:0097381"(photoreceptor disc membrane)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|rcsb pdb:4YHJ|reactome:R-HSA-2514859|genbank_protein_gi:51873047(identity)|refseq:NP_001004057(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:b9KS8dXSBGHRCbutTwr5h87uf3M9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9ULD4 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1753470|uniprotkb:A6NJE2|uniprotkb:Q5R3K8|ensembl:ENSP00000350267|intact:EBI-2860074|uniprotkb:A6ND56|uniprotkb:B7ZLN5|uniprotkb:E7EX85|uniprotkb:Q17RB6 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:brpf3_human(display_long)|uniprotkb:BRPF3(gene name)|psi-mi:BRPF3(display_short)|uniprotkb:KIAA1286(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:XP_011512791.1|refseq:XP_005249067.1|refseq:XP_005249068.1|refseq:NP_056510.2|ensembl:ENSG00000096070(gene)|ensembl:ENST00000357641(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042005|mint:Q9ULD4|rcsb pdb:3PFS|reactome:R-HSA-114608|reactome:R-HSA-3214847|reactome:R-HSA-6804758|interpro:IPR018359|genbank_protein_gi:109659078(identity)|refseq:AAI17388(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:CgyLb1z0upVoKfJxtzvybQ6NAkE9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9UKU0 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-6509553|ensembl:ENSP00000368542|uniprotkb:O94924|uniprotkb:O95829|uniprotkb:Q108M9|uniprotkb:Q108N0|uniprotkb:Q86TN7|uniprotkb:J3KPG3|uniprotkb:Q4G191 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:acsl6_human(display_long)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:ACSL6(gene name)|psi-mi:ACSL6(display_short)|uniprotkb:ACS2(gene name synonym)|uniprotkb:FACL6(gene name synonym)|uniprotkb:KIAA0837(gene name synonym)|uniprotkb:LACS5(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000164398(gene)|ensembl:ENST00000379240(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0047676"(arachidonate-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|reactome:R-HSA-75876|refseq:NP_001009185.1|refseq:NP_001192176.1|refseq:NP_001192177.1|refseq:NP_001192179.1|refseq:NP_001192180.1|refseq:NP_056071.2|genbank_protein_gi:28703684(identity)|refseq:AAH47453(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:dTINpdgyDPWXzLyx8I68IVa0pEs9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9UJS0 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1222503|uniprotkb:O14566|uniprotkb:O14575|uniprotkb:Q9NZW1|uniprotkb:Q9UNI7|uniprotkb:Q546F9|ensembl:ENSP00000265631 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:cmc2_human(display_long)|uniprotkb:SLC25A13(gene name)|psi-mi:SLC25A13(display_short)|uniprotkb:ARALAR2(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 13(gene name synonym)|uniprotkb:Citrin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_055066.1|refseq:NP_001153682.1|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0009066"(aspartate family amino acid metabolic process)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045333"(cellular respiration)|go:"GO:0051592"(response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR023395|interpro:IPR029658|mint:Q9UJS0|rcsb pdb:4P5W|reactome:R-HSA-1268020|reactome:R-HSA-70263|reactome:R-HSA-8963693|ensembl:ENSG00000004864(gene)|ensembl:ENST00000265631(transcript)|genbank_protein_gi:7657581(identity)|refseq:NP_055066(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 10 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:YtrKzkRujsJ/hzl2bJaLgJAAswI9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9UHC7 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-373524|uniprotkb:Q6GSF1|uniprotkb:Q9H0G0|uniprotkb:Q9UEZ7|uniprotkb:A4D1T7|uniprotkb:B3KXB4|uniprotkb:Q256Y7|uniprotkb:Q59G11|uniprotkb:Q9UHW2|ensembl:ENSP00000255977 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:mkrn1_human(display_long)|uniprotkb:MKRN1(gene name)|psi-mi:MKRN1(display_short)|uniprotkb:RING finger protein 61(gene name synonym)|uniprotkb:RNF61(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:XP_011514299.1|refseq:XP_011514300.1|refseq:NP_001138597.1|refseq:NP_038474.2|ensembl:ENSP00000255977|ensembl:ENST00000443720|ensembl:ENSP00000416369|ensembl:ENST00000474576|ensembl:ENSP00000417863|ensembl:ENSG00000133606(gene)|ensembl:ENST00000255977(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q9UHC7|reactome:R-HSA-198323|reactome:R-HSA-8948751|reactome:R-HSA-983168|genbank_protein_gi:223468620(identity)|refseq:NP_038474(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:oU5t6f0XORO+6RMyVdR3FqDlh0Y9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9NXZ2 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-10316543|uniprotkb:B4E0C8|uniprotkb:Q6NXR1|ensembl:ENSP00000359361 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ddx43_human(display_long)|uniprotkb:DDX43(gene name)|psi-mi:DDX43(display_short)|uniprotkb:Cancer/testis antigen 13(gene name synonym)|uniprotkb:DEAD box protein 43(gene name synonym)|uniprotkb:DEAD box protein HAGE(gene name synonym)|uniprotkb:HAGE(gene name synonym)|uniprotkb:Helical antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_061135.2|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR036612|ensembl:ENSG00000080007(gene)|ensembl:ENST00000370336(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|genbank_protein_gi:45219880(identity)|refseq:AAH66938(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 5 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:66lEHz7ugWNP7M3l2sl1CQTajGs9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9NRW1 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1760079|uniprotkb:D3DND3|uniprotkb:B2R5Z9|uniprotkb:Q92929|uniprotkb:B7Z337|ensembl:ENSP00000285208|ensembl:ENSP00000437797 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:rab6b_human(display_long)|uniprotkb:RAB6B(gene name)|psi-mi:RAB6B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:XP_011511195.1|refseq:NP_057661.3|ensembl:ENSG00000154917(gene)|ensembl:ENST00000285208(transcript)|ensembl:ENST00000543906(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0098793"(presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9NRW1|rcsb pdb:2E9S|rcsb pdb:2FE4|rcsb pdb:2FFQ|reactome:R-HSA-6811436|reactome:R-HSA-6811440|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|genbank_protein_gi:50927456(identity)|refseq:AAH78662(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 5 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:GmhjkLknjr8fxoUBxNx5ak5S/hQ9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9HC62 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-714881|uniprotkb:Q8IW97|uniprotkb:Q96SR2|uniprotkb:Q9P2L5|uniprotkb:B4DQ42|intact:EBI-10966410|ensembl:ENSP00000296257 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:senp2_human(display_long)|uniprotkb:Sentrin/SUMO-specific protease SENP2(gene name synonym)|uniprotkb:SMT3-specific isopeptidase 2(gene name synonym)|uniprotkb:Axam2(gene name synonym)|uniprotkb:SENP2(gene name)|psi-mi:SENP2(display_short)|uniprotkb:KIAA1331(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_067640.2|ensembl:ENSG00000163904(gene)|ensembl:ENST00000296257(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016926"(protein desumoylation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|mint:Q9HC62|rcsb pdb:1TGZ|rcsb pdb:1TH0|rcsb pdb:2IO0|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:3ZO5|rcsb pdb:5AEK|reactome:R-HSA-3065679|rcsb pdb:2IO1|dip:DIP-29254N|genbank_protein_gi:10314023(identity)|refseq:AAG15309(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 7 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:zYThN+7SovDIV6Ly58vwds2CRZ49606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9H5N1 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-3940735|ensembl:ENSP00000350934 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:rabe2_human(display_long)|uniprotkb:RABEP2(gene name)|psi-mi:RABEP2(display_short)|uniprotkb:RABPT5B(gene name synonym)|uniprotkb:Rabaptin-5beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000177548(gene)|ensembl:ENST00000358201(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005769"(early endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0008083"(growth factor activity)|go:"GO:0015031"(protein transport)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR003914(Rabaptin)|interpro:IPR015390(Rabaptin, GTPase-Rab5 binding)|interpro:IPR018514|interpro:IPR029882|refseq:NP_079092.2|genbank_protein_gi:117956403(identity)|refseq:NP_079092(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:pcTL9W2UHdUPv+Nl+bHFRXEoK309606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9H2D6 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-715619|uniprotkb:B1AHD4|uniprotkb:B1AHD7|uniprotkb:O94797|uniprotkb:Q2PZW8|uniprotkb:Q2Q3Z9|uniprotkb:Q2Q400|uniprotkb:Q5R3M6|uniprotkb:Q96DW1|uniprotkb:Q9BT77|uniprotkb:Q9BTL7|uniprotkb:Q9BY98|uniprotkb:Q9Y3L4|ensembl:ENSP00000496394|intact:EBI-2560917|uniprotkb:F2Z2W0|uniprotkb:F8W6V6 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:tara_human(display_long)|uniprotkb:Protein Tara(gene name synonym)|uniprotkb:Trio-associated repeat on actin(gene name synonym)|uniprotkb:TRIOBP(gene name)|psi-mi:TRIOBP(display_short)|uniprotkb:KIAA1662(gene name synonym)|uniprotkb:TARA(gene name synonym)|uniprotkb:HRIHFB2122(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001034230.1|refseq:NP_008963.3|refseq:NP_619538.2|ensembl:ENSG00000100106(gene)|ensembl:ENST00000644935(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030047"(actin modification)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045159"(myosin II binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051301"(cell division)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|mint:Q9H2D6|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|genbank_protein_gi:13177667(identity)|refseq:AAH03618(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 7 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:2evioSQxAnH1x5VPGsZyK+fJTY09606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9BYC5 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2869363|uniprotkb:Q9P2U6|uniprotkb:Q9P2U5|uniprotkb:O00235|uniprotkb:Q9BYC6|uniprotkb:B4DFS7|uniprotkb:G3V5N0|uniprotkb:Q8IUA5|ensembl:ENSP00000353910|ensembl:ENSP00000501213|ensembl:ENSP00000378087 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:fut8_human(display_long)|uniprotkb:FUT8(gene name)|psi-mi:FUT8(display_short)|uniprotkb:Fucosyltransferase 8(gene name synonym)|uniprotkb:"GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase"(gene name synonym)|uniprotkb:GDP-fucose--glycoprotein fucosyltransferase(gene name synonym)|uniprotkb:Glycoprotein 6-alpha-L-fucosyltransferase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_004471.4|refseq:NP_835368.1|refseq:NP_835369.1|ensembl:ENSG00000033170(gene)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:6VLE|go:"GO:1900407"(regulation of cellular response to oxidative stress)|interpro:IPR001452(Src homology-3)|rcsb pdb:6X5H|interpro:IPR015827("Alpha-(1,6)-fucosyltransferase, eukaryotic type")|interpro:IPR027350|interpro:IPR035653|interpro:IPR036028|mint:Q9BYC5|rcsb pdb:2DE0|rcsb pdb:6VLD|rcsb pdb:6X5R|rcsb pdb:6X5S|rcsb pdb:6X5T|rcsb pdb:6X5U|reactome:R-HSA-9694548|reactome:R-HSA-975578|ensembl:ENST00000360689(transcript)|ensembl:ENST00000394586(transcript)|ensembl:ENST00000673929(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008424"(glycoprotein 6-alpha-L-fucosyltransferase activity)|go:"GO:0009312"(oligosaccharide biosynthetic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0019082"(viral protein processing)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033578"(protein glycosylation in Golgi)|go:"GO:0036071"(N-glycan fucosylation)|go:"GO:0042355"(L-fucose catabolic process)|go:"GO:0043112"(receptor metabolic process)|go:"GO:0046368"(GDP-L-fucose metabolic process)|go:"GO:0046921"("alpha-(1->6)-fucosyltransferase activity")|genbank_protein_gi:119601320(identity)|refseq:EAW80914(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:4ExQD5i1NzMB4ZN+jMDAgEDfXmg9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9BWT3 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-11060140|uniprotkb:Q9H8L2|uniprotkb:Q969N1|uniprotkb:Q59G05|uniprotkb:B2RBH4|uniprotkb:Q9HAD0|ensembl:ENSP00000238714 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:papog_human(display_long)|uniprotkb:PAPOLG(gene name)|psi-mi:PAPOLG(display_short)|uniprotkb:"Neo-poly(A) polymerase"(gene name synonym)|uniprotkb:PAP2(gene name synonym)|uniprotkb:PAPG(gene name synonym)|uniprotkb:Polynucleotide adenylyltransferase gamma(gene name synonym)|uniprotkb:SRP RNA 3'-adenylating enzyme(gene name synonym)|uniprotkb:Signal recognition particle RNA-adenylating enzyme(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_075045.2|refseq:XP_005264557.1|ensembl:ENSG00000115421(gene)|ensembl:ENST00000238714(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0043631"(RNA polyadenylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR007010("Poly(A) polymerase, RNA-binding region")|interpro:IPR007012("Poly(A) polymerase, central region")|interpro:IPR011068(Nucleotidyltransferase, class I, C-terminal-like)|interpro:IPR043519|rcsb pdb:4LT6|genbank_protein_gi:16306568(identity)|refseq:NP_075045(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 3 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:T753BGfFCqeiN8vUSvhKUH5k2/Y9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9BQA1 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_077007.1|refseq:NP_001303991.1|refseq:NP_001303992.1|refseq:NP_001303993.1|dip:DIP-38172N|ensembl:ENSG00000116455(gene)|ensembl:ENST00000235090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0034709"(methylosome)|go:"GO:0045495"(pole plasm)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858|genbank_protein_gi:14495615(identity)|refseq:AAH09411(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 17 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:0q4wunYtHalObC8r1wphhelIpr49606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96RR1 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-716458|uniprotkb:Q6MZX2|uniprotkb:Q96RR0|uniprotkb:Q6PJP5|uniprotkb:B2CQL2|ensembl:ENSP00000309595 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:peo1_human(display_long)|uniprotkb:TWNK(gene name)|psi-mi:TWNK(display_short)|uniprotkb:C10orf2(gene name synonym)|uniprotkb:PEO1(gene name synonym)|uniprotkb:Progressive external ophthalmoplegia 1 protein(gene name synonym)|uniprotkb:T7 gp4-like protein with intramitochondrial nucleoid localization(gene name synonym)|uniprotkb:T7-like mitochondrial DNA helicase(gene name synonym)|uniprotkb:Twinkle protein, mitochondrial(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001157284.1|refseq:NP_068602.2|ensembl:ENST00000311916(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|ensembl:ENSG00000107815(gene)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR027417|interpro:IPR034154|mint:Q96RR1|reactome:R-HSA-2151201|genbank_protein_gi:39725942(identity)|refseq:NP_068602(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:asX2NETd8o4GZrWe8gIUntbtUpA9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96RL8 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404757 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q96rl8_human(display_long)|uniprotkb:NIMP(gene name)|psi-mi:NIMP(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0005739"(mitochondrion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036291|interpro:IPR002364(Quinone oxidoreductase/zeta-crystallin, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR037397|genbank_protein_gi:14522882(identity)|refseq:AAK64603(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:q7EB/IGVuZabqcp2j/TvIjE18Zo9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96JM3 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU|genbank_protein_gi:13435972(identity)|refseq:AAH04820(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 19 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96CG3 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-740711|ensembl:ENSP00000354911|ensembl:ENSP00000424231 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:tifa_human(display_long)|uniprotkb:Putative NF-kappa-B-activating protein 20(gene name synonym)|uniprotkb:TIFA(gene name)|psi-mi:TIFA(display_short)|uniprotkb:T2BP(gene name synonym)|uniprotkb:TRAF2-binding protein(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_443096.1|ensembl:ENSG00000145365(gene)|ensembl:ENST00000361717(transcript)|ensembl:ENST00000500655(transcript)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|rcsb pdb:4YM4|rcsb pdb:4ZGI|rcsb pdb:5ZUJ|rcsb pdb:6A33|reactome:R-HSA-9645460|dip:DIP-40185N|genbank_protein_gi:33563370(identity)|refseq:NP_443096(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 21 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:ppKFaTK8YYWSscDQlE1n/mONziY9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96AQ8 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404755|ensembl:ENSP00000368468|uniprotkb:Q96JS7|uniprotkb:Q9H7F8 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:mcur1_human(display_long)|uniprotkb:MCUR1(gene name)|psi-mi:MCUR1(display_short)|uniprotkb:C6orf79(gene name synonym)|uniprotkb:CCDC90A(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 90A, mitochondrial(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000050393(gene)|ensembl:ENST00000379170(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070509"(calcium ion import)|interpro:IPR012439(Protein of unknown function DUF1640)|interpro:IPR024461|refseq:NP_001026883.1|dip:DIP-61861N|genbank_protein_gi:72534716(identity)|refseq:NP_001026883(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 15 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:I1h0wgnhkXLdFU8mn6kSj0sjIQU9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8TB52 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2556210|uniprotkb:Q9BXZ7|ensembl:ENSP00000237281 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:fbx30_human(display_long)|uniprotkb:FBX30(gene name synonym)|uniprotkb:FBXO30(gene name)|psi-mi:FBXO30(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_115521.3|refseq:XP_011534479.1|ensembl:ENSG00000118496(gene)|ensembl:ENST00000237281(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031890|interpro:IPR036047|interpro:IPR043013|rcsb pdb:2YRE|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001335021.1|refseq:XP_016866842.1|genbank_protein_gi:34577055(identity)|refseq:NP_115521(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:ZSddVg47+VIHJBP2vthCSVlnZkQ9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8IVL1 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-741200|ensembl:ENSP00000379396|uniprotkb:Q8IVK3|uniprotkb:Q8IVK4|uniprotkb:Q8IVK5|uniprotkb:Q8IVK6|uniprotkb:Q8IVK7|uniprotkb:Q8IVK8|uniprotkb:Q8NHC9|uniprotkb:Q8NHD0|uniprotkb:Q8TDE9|uniprotkb:Q8TDF0|uniprotkb:Q8TEB3|uniprotkb:Q96B30|uniprotkb:Q9NUZ6|uniprotkb:Q9NVM7|uniprotkb:Q9P2C8|uniprotkb:A6NEC1 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:nav2_human(display_long)|uniprotkb:Helicase APC down-regulated 1(gene name synonym)|uniprotkb:Retinoic acid inducible in neuroblastoma 1(gene name synonym)|uniprotkb:Steerin-2(gene name synonym)|uniprotkb:Pore membrane and/or filament-interacting-like protein 2(gene name synonym)|uniprotkb:Unc-53 homolog 2(gene name synonym)|uniprotkb:NAV2(gene name)|psi-mi:NAV2(display_short)|uniprotkb:HELAD1(gene name synonym)|uniprotkb:KIAA1419(gene name synonym)|uniprotkb:POMFIL2(gene name synonym)|uniprotkb:RAINB1(gene name synonym)|uniprotkb:STEERIN2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000166833(gene)|ensembl:ENST00000396087(transcript)|go:"GO:0003025"(regulation of systemic arterial blood pressure by baroreceptor feedback)|go:"GO:0005524"(ATP binding)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008201"(heparin binding)|go:"GO:0021554"(optic nerve development)|go:"GO:0021563"(glossopharyngeal nerve development)|go:"GO:0021564"(vagus nerve development)|go:"GO:0022008"(neurogenesis)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR036872|interpro:IPR039041|rcsb pdb:2YRN|refseq:NP_001104488.1|refseq:NP_660093.2|refseq:NP_892009.3|refseq:XP_011518754.1|refseq:NP_001231892.1|refseq:XP_006718431.1|refseq:NP_001104489.1|genbank_protein_gi:19744388(identity)|refseq:AAL96479(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 19 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:OfSGuKrpZGae4NcKYPRCXm4/CcQ9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8NEM8 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404751|uniprotkb:B7Z827|uniprotkb:Q9H965 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:cbpc3_human(display_long)|uniprotkb:Protein deglutamylase CCP3(gene name synonym)|uniprotkb:AGBL3(gene name)|psi-mi:AGBL3(display_short)|uniprotkb:ATP/GTP-binding protein-like 3(gene name synonym)|uniprotkb:CCP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035610"(protein side chain deglutamylation)|interpro:IPR040626|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|refseq:NP_848658.3|refseq:XP_016867625.1|refseq:XP_016867626.1|reactome:R-HSA-8955332|genbank_protein_gi:222352158(identity)|refseq:NP_848658(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:ovXQLxuhAtc6e3ylMgtfBsieNTc9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8NEE8 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404749|ensembl:ENSP00000362386|uniprotkb:B4DYG4|uniprotkb:B5ME24|uniprotkb:Q5JU66|uniprotkb:Q96M72 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ttc16_human(display_long)|uniprotkb:TTC16(gene name)|psi-mi:TTC16(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) interpro:IPR019734|ensembl:ENSG00000167094(gene)|ensembl:ENST00000373289(transcript)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_001303966.1|refseq:NP_659402.1|genbank_protein_gi:21410623(identity)|refseq:AAH31281(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:pUbXwmKSvtpZiQ/LWeQNe6i0s6I9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8ND71 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2824826|ensembl:ENSP00000305107|uniprotkb:A0A090N8H2 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:gima8_human(display_long)|uniprotkb:GIMAP8(gene name)|psi-mi:GIMAP8(display_short)|uniprotkb:IAN9(gene name synonym)|uniprotkb:IANT(gene name synonym)|uniprotkb:Immune-associated nucleotide-binding protein 9(gene name synonym)|uniprotkb:Protein IanT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000171115(gene)|ensembl:ENST00000307271(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0070232"(regulation of T cell apoptotic process)|interpro:IPR006703(AIG1)|interpro:IPR027417|refseq:NP_783161.1|refseq:XP_005250007.1|genbank_protein_gi:28416956(identity)|refseq:NP_783161(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 7 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:vDWdNOF9z1nfhrz8Yx/ONT8EyqM9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8J014 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404747 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q8j014_human(display_long)|uniprotkb:rps2(gene name)|psi-mi:rps2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018192|interpro:IPR020568|genbank_protein_gi:23491733(identity)|refseq:BAC16801(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 19 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:dbb3tyGA7HWV9GnGrehsyj0aomk9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8IZ69 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2515774|uniprotkb:Q9H732|uniprotkb:Q32P57|uniprotkb:Q96ME6|uniprotkb:D3DX25|ensembl:ENSP00000252136|ensembl:ENSP00000385807 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:trm2a_human(display_long)|uniprotkb:TRMT2A(gene name)|psi-mi:TRMT2A(display_short)|uniprotkb:HTF9C(gene name synonym)|uniprotkb:HpaII tiny fragments locus 9c protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_073564.3|refseq:NP_892029.2|refseq:NP_001244923.1|ensembl:ENSP00000252136|ensembl:ENSP00000385807|ensembl:ENST00000404751|ensembl:ENSP00000384968|ensembl:ENSG00000099899(gene)|ensembl:ENST00000252136(transcript)|ensembl:ENST00000403707(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0008173"(RNA methyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010280("(Uracil-5)-methyltransferase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029063|interpro:IPR034262|interpro:IPR035979|mint:Q8IZ69|genbank_protein_gi:34222389(identity)|refseq:NP_892029(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 7 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:/G2YDfinTNhJ+mPHfHOwSsyHQxE9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q86VQ0 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-6658186|ensembl:ENSP00000358861|ensembl:ENSP00000376686|uniprotkb:Q9BWX7|uniprotkb:E1P542 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:lca5_human(display_long)|uniprotkb:LCA5(gene name)|psi-mi:LCA5(display_short)|uniprotkb:C6orf152(gene name synonym)|uniprotkb:Leber congenital amaurosis 5 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000135338(gene)|ensembl:ENST00000369846(transcript)|ensembl:ENST00000392959(transcript)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0015031"(protein transport)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045494"(photoreceptor cell maintenance)|interpro:IPR026188|interpro:IPR026684|interpro:IPR028933|refseq:XP_011533806.1|refseq:NP_001116241.1|refseq:NP_859065.2|refseq:XP_005248722.1|genbank_protein_gi:170650670(identity)|refseq:NP_859065(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 6 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:PCjP620A20P4KItwv7Zsd0/F4zk9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q86VD7 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-6598313|ensembl:ENSP00000326693|uniprotkb:D2T2J5|uniprotkb:O14553|uniprotkb:O43378 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:s2542_human(display_long)|uniprotkb:SLC25A42(gene name)|psi-mi:SLC25A42(display_short)|uniprotkb:Solute carrier family 25 member 42(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000181035(gene)|ensembl:ENST00000318596(transcript)|go:"GO:0005347"(ATP transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0015217"(ADP transmembrane transporter activity)|go:"GO:0015228"(coenzyme A transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|go:"GO:0015867"(ATP transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035349"(coenzyme A transmembrane transport)|go:"GO:0043262"(adenosine-diphosphatase activity)|go:"GO:0080121"(AMP transport)|go:"GO:0080122"(AMP transmembrane transporter activity)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002167(Graves disease carrier protein)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR018108|interpro:IPR023395|refseq:XP_011526239.1|refseq:NP_848621.2|refseq:XP_005259918.1|refseq:NP_001308473.1|genbank_protein_gi:28277020(identity)|refseq:AAH45598(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 18 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:BOlIYSw1Drw4klVrplid5Rem9r49606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q6ZWL3 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-3925755|uniprotkb:B7U6W2|uniprotkb:Q6ZTM4|ensembl:ENSP00000368079 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:cp4v2_human(display_long)|uniprotkb:CYP4V2(gene name)|psi-mi:CYP4V2(display_short)|uniprotkb:Docosahexaenoic acid omega-hydroxylase CYP4V2(gene name synonym)|uniprotkb:Long-chain fatty acid omega-monooxygenase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_997235.3|ensembl:ENSG00000145476(gene)|ensembl:ENST00000378802(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007601"(visual perception)|go:"GO:0010430"(fatty acid omega-oxidation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0102033"(long-chain fatty acid omega-hydroxylase activity)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR036396|reactome:R-HSA-211976|reactome:R-HSA-2453902|interpro:IPR001128(Cytochrome P450)|genbank_protein_gi:187960086(identity)|refseq:NP_997235(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 10 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:FGgIcjkLVbJRA8wAfThm1+Zupts9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q6ZV73 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-3959469|uniprotkb:Q9NUR8|uniprotkb:Q96D44|uniprotkb:Q7Z2Z7|uniprotkb:Q9P2I5|uniprotkb:Q6ZR53|ensembl:ENSP00000344446 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:fgd6_human(display_long)|uniprotkb:FGD6(gene name)|psi-mi:FGD6(display_short)|uniprotkb:KIAA1362(gene name synonym)|uniprotkb:ZFYVE24(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_060821.3|ensembl:ENSG00000180263(gene)|ensembl:ENST00000343958(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR037743|mint:Q6ZV73|genbank_protein_gi:7243105(identity)|refseq:BAA92600(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 6 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:tGTBRM2CAnj8C/lEzaVA7vqwRfs9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q6ZN84 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404745|ensembl:ENSP00000415528|uniprotkb:A0AVL7|uniprotkb:Q53FW3|uniprotkb:Q9H5E5 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ccd81_human(display_long)|uniprotkb:CCDC81(gene name)|psi-mi:CCDC81(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENST00000445632(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|interpro:IPR026295|interpro:IPR028034|interpro:IPR040673|ensembl:ENSG00000149201(gene)|refseq:NP_001149946.1|refseq:NP_068599.3|genbank_protein_gi:226493512(identity)|refseq:NP_001149946(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 5 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:JoFC8dj1sUb3PCxIb9iryJmiQRU9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q6XUX3 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1049520|uniprotkb:O75060|uniprotkb:Q17R94|uniprotkb:Q5RKT0|uniprotkb:Q6IN87|uniprotkb:Q6P997|uniprotkb:Q86Y03|ensembl:ENSP00000356130|uniprotkb:Q9P1S5|uniprotkb:B7ZL64 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:dusty_human(display_long)|uniprotkb:Dusty protein kinase(gene name synonym)|uniprotkb:RIP-homologous kinase(gene name synonym)|uniprotkb:Sugen kinase 496(gene name synonym)|uniprotkb:DSTYK(gene name)|psi-mi:DSTYK(display_short)|uniprotkb:KIAA0472(gene name synonym)|uniprotkb:RIP5(gene name synonym)|uniprotkb:HDCMD38P(orf name)|uniprotkb:SGK496(gene name synonym)|uniprotkb:RIPK5(gene name synonym)|uniprotkb:Receptor-interacting serine/threonine-protein kinase 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000133059(gene)|ensembl:ENST00000367162(transcript)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|refseq:NP_056190.1|refseq:NP_955749.1|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|genbank_protein_gi:48734889(identity)|refseq:AAH72406(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:jGd7cCZNCY6LlTWJTPt43MOnZ4Y9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q6Q0C0 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-307556|uniprotkb:Q9H073|ensembl:ENSP00000318944 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:traf7_human(display_long)|uniprotkb:TRAF7(gene name)|psi-mi:TRAF7(display_short)|uniprotkb:TNF receptor-associated factor 7(gene name synonym)|uniprotkb:RING finger and WD repeat-containing protein 1(gene name synonym)|uniprotkb:RING finger protein 119(gene name synonym)|uniprotkb:RFWD1(gene name synonym)|uniprotkb:RNF119(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_115647.2|ensembl:ENSG00000131653(gene)|ensembl:ENST00000326181(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017907|interpro:IPR019775|interpro:IPR020472|interpro:IPR027370|interpro:IPR036322|mint:Q6Q0C0|reactome:R-HSA-983168|genbank_protein_gi:119605952(identity)|refseq:EAW85546(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 5 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:46dtsS1OairncB0fnINSW1aY2789606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q6NVV8 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404743 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q6nvv8_human(display_long)|uniprotkb:IAH1(gene name)|psi-mi:IAH1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0016042"(lipid catabolic process)|interpro:IPR036514|interpro:IPR013830(Esterase, SGNH hydrolase-type)|refseq:NP_001307789.1|genbank_protein_gi:45709292(identity)|refseq:AAH67865(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 21 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:rAn885z1uyXcVtjPKUEffO+BkTo9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q6FHH0 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404741 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q6fhh0_human(display_long)|uniprotkb:CCNI(gene name)|psi-mi:CCNI(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0051726"(regulation of cell cycle)|interpro:IPR036915|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028856|interpro:IPR039361|genbank_protein_gi:62089118(identity)|refseq:BAD93003(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 15 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:KwhAs3ugD0AdBE+RSX1rQfXSpIc9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q68DK2 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-15316611|ensembl:ENSP00000251119|uniprotkb:B1B5Y3|uniprotkb:B4E2U3|uniprotkb:O15035|uniprotkb:Q68DT9|uniprotkb:Q6AW90|uniprotkb:Q6ZR50|uniprotkb:Q7Z3A4|uniprotkb:Q7Z3I1|uniprotkb:Q8N4W7|uniprotkb:Q96H43 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:zfy26_human(display_long)|uniprotkb:ZFYVE26(gene name)|psi-mi:ZFYVE26(display_short)|uniprotkb:FYVE domain-containing centrosomal protein(gene name synonym)|uniprotkb:KIAA0321(gene name synonym)|uniprotkb:Spastizin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000072121(gene)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0030496"(midbody)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR028730|mint:Q68DK2|ensembl:ENST00000347230(transcript)|refseq:NP_056161.2|genbank_protein_gi:28175105(identity)|refseq:AAH33235(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:N79oTMk4AShEluoFKPJekz42uBg9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q66K75 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404739 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q66k75_human(display_long)|uniprotkb:MYH11(gene name)|psi-mi:MYH11(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0016459"(myosin complex)|interpro:IPR002928(Myosin tail)|genbank_protein_gi:2352947(identity)|refseq:AAB69327(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 5 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:w/o/jTDLESmwo6yaWL2fc4lppVY9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q5VTQ0 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-4289975|uniprotkb:Q8N267|uniprotkb:Q8IVR7|ensembl:ENSP00000422496|uniprotkb:A5PLN1|uniprotkb:B4DQ10|uniprotkb:B4DQX4|uniprotkb:B4DW93|uniprotkb:Q8IXZ6 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:tt39b_human(display_long)|uniprotkb:TTC39B(gene name)|psi-mi:TTC39B(display_short)|uniprotkb:C9orf52(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000155158(gene)|ensembl:ENST00000512701(transcript)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0010874"(regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0090181"(regulation of cholesterol metabolic process)|interpro:IPR019412|interpro:IPR019734|interpro:IPR034305|refseq:XP_011516034.1|refseq:NP_001161813.1|refseq:NP_689787.2|refseq:NP_001161811.1|refseq:NP_001161812.1|refseq:NP_001161814.1|refseq:XP_016869800.1|refseq:XP_016869801.1|dip:DIP-62094N|genbank_protein_gi:270265889(identity)|refseq:NP_001161812(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 6 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:hnHLzHeBn8OVA5EYDszCLcxKlBA9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q5VTH9 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404737|ensembl:ENSP00000360065|uniprotkb:A8K9W5|uniprotkb:B5MDT3|uniprotkb:Q5VTI0|uniprotkb:H7BY80|uniprotkb:Q8N5G5|uniprotkb:Q9H5R9|uniprotkb:Q9UF44 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:dnai4_human(display_long)|uniprotkb:DNAI4(gene name)|psi-mi:DNAI4(display_short)|uniprotkb:WD repeat-containing protein 78(gene name synonym)|uniprotkb:WDR78(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000152763(gene)|ensembl:ENST00000371026(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003341"(cilium movement)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0031514"(motile cilium)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:0070286"(axonemal dynein complex assembly)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0005858"(axonemal dynein complex)|go:"GO:0005930"(axoneme)|refseq:NP_079039.4|refseq:NP_996897.2|genbank_protein_gi:282165778(identity)|refseq:NP_079039(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:iiZSWgDRBpiyP5Yhl+/gHc0ufH09606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q5R372 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2810417|uniprotkb:Q8WV78|uniprotkb:Q9UQP5|uniprotkb:Q5R369|uniprotkb:Q9UQ19|uniprotkb:Q8N921|uniprotkb:O75059|uniprotkb:Q3ZTR8|uniprotkb:Q9Y6Y5|uniprotkb:Q9NSP8|uniprotkb:Q8IVV0|intact:EBI-3203909|uniprotkb:Q9Y6Y6|ensembl:ENSP00000251507 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:rbg1l_human(display_long)|uniprotkb:RABGAP1L(gene name)|psi-mi:RABGAP1L(display_short)|uniprotkb:HHL(gene name synonym)|uniprotkb:KIAA0471(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001030307.1|refseq:NP_055672.3|ensembl:ENSG00000152061(gene)|ensembl:ENST00000251507(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022164|interpro:IPR033185|interpro:IPR035969|rcsb pdb:3HZJ|refseq:NP_001230692.1|refseq:NP_001230694.1|genbank_protein_gi:34596278(identity)|refseq:AAQ76819(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:cvAqfETiY1zUH+PVyBtdzMuOPD09606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q59FY4 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-10049509|ensembl:ENSP00000483969|ensembl:ENSP00000488846 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q59fy4_human(display_long)|uniprotkb:ACACA(gene name)|psi-mi:ACACA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000275176(gene)|ensembl:ENSG00000278540(gene)|ensembl:ENST00000619546(transcript)|ensembl:ENST00000632453(transcript)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006633"(fatty acid biosynthetic process)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR029045|interpro:IPR034733|genbank_protein_gi:62088230(identity)|refseq:BAD92562(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 1 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:+mtBPqrwam54pjT8gYaHCkzqUOk9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q53GS7 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236|genbank_protein_gi:193785996(identity)|refseq:BAG50972(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q1RLM6 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404735 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q1rlm6_human(display_long)|uniprotkb:FBXL10(gene name)|psi-mi:FBXL10(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0003677"(DNA binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR041070|interpro:IPR041667|genbank_protein_gi:92098161(identity)|refseq:AAI15381(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 3 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:fnuXI7uyguLEhR8/rSXGMnN4ALE9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q14BN4 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1|genbank_protein_gi:10047277(identity)|refseq:BAB13427(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q14974 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249|genbank_protein_gi:10120904(identity)|refseq:NP_002256(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q12905 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-357925|uniprotkb:A6NDB0|uniprotkb:Q5SR10|uniprotkb:Q5SR11|uniprotkb:Q7L7R3|uniprotkb:Q9BWD4|uniprotkb:Q9P1N0|uniprotkb:B2R8G7|ensembl:ENSP00000355011 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ilf2_human(display_long)|uniprotkb:PRO3063(orf name)|uniprotkb:NF45(gene name synonym)|uniprotkb:ILF2(gene name)|psi-mi:ILF2(display_short)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_004506.2|refseq:NP_001254738.1|ensembl:ENSG00000143621(gene)|ensembl:ENST00000361891(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q12905|reactome:R-HSA-6798695|genbank_protein_gi:532313(identity)|refseq:AAA20993(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 16 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:HwUDuY6Ev7csoTThxZCW8nJT88o9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q12901 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-10747670|uniprotkb:A2BDE6|uniprotkb:B2RB63|uniprotkb:B4DM95|uniprotkb:J3KQ08|uniprotkb:Q6AZZ8|uniprotkb:Q9UIE1|uniprotkb:Q9UK14|ensembl:ENSP00000270014|ensembl:ENSP00000465691|ensembl:ENSP00000481677 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:zn155_human(display_long)|uniprotkb:ZNF155(gene name)|psi-mi:ZNF155(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001247415.1|refseq:NP_001247416.1|refseq:NP_001247417.1|refseq:NP_003436.3|refseq:NP_932355.2|refseq:XP_005259272.1|refseq:XP_011525580.1|refseq:XP_011525581.1|ensembl:ENSG00000204920(gene)|ensembl:ENST00000270014(transcript)|ensembl:ENST00000590615(transcript)|ensembl:ENST00000611002(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:XP_016882737.1|genbank_protein_gi:6118377(identity)|refseq:AAF04102(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 8 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:J8gyqMCzYyHo8slIvMPDwKWy1oM9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P68371 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|genbank_protein_gi:5174735(identity)|refseq:NP_006079(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 13 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P68363 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328|genbank_protein_gi:340021(identity)|refseq:AAA91576(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 13 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P62917 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N|genbank_protein_gi:4506663(identity)|refseq:NP_000964(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 19 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P54136 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-355482|uniprotkb:Q9BWA1|uniprotkb:B2RBS9|uniprotkb:Q53GY4|intact:EBI-28985219|ensembl:ENSP00000231572 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:syrc_human(display_long)|uniprotkb:RARS1(gene name)|psi-mi:RARS1(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:RARS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_002878.2|ensembl:ENSG00000113643(gene)|ensembl:ENST00000231572(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0034618"(arginine binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR035684|interpro:IPR036695|mint:P54136|rcsb pdb:4Q2T|rcsb pdb:4Q2X|rcsb pdb:4Q2Y|rcsb pdb:4R3Z|rcsb pdb:4ZAJ|reactome:R-HSA-2408522|reactome:R-HSA-379716|ensembl:ENSP00000231572|genbank_protein_gi:1217668(identity)|refseq:AAB35627(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 6 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:oM9gWF1NucjgVjBFm4DcjmnQNCE9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P52732 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-355697|uniprotkb:A0AV49|uniprotkb:Q15716|uniprotkb:Q5VWX0|uniprotkb:B2RMV3|ensembl:ENSP00000260731 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:kif11_human(display_long)|uniprotkb:KIF11(gene name)|psi-mi:KIF11(display_short)|uniprotkb:EG5(gene name synonym)|uniprotkb:KNSL1(gene name synonym)|uniprotkb:TRIP5(gene name synonym)|uniprotkb:Kinesin-related motor protein Eg5(gene name synonym)|uniprotkb:Kinesin-like spindle protein HKSP(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 5(gene name synonym)|uniprotkb:Kinesin-like protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_004514.2|ensembl:ENSG00000138160(gene)|ensembl:ENST00000260731(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|rcsb pdb:1X88|rcsb pdb:1YRS|rcsb pdb:2FKY|rcsb pdb:2FL2|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR025901|interpro:IPR027417|interpro:IPR036961|rcsb pdb:1II6|rcsb pdb:1Q0B|rcsb pdb:2FL6|rcsb pdb:2FME|rcsb pdb:2G1Q|rcsb pdb:2GM1|rcsb pdb:2IEH|rcsb pdb:2PG2|rcsb pdb:2Q2Y|rcsb pdb:2Q2Z|rcsb pdb:2UYI|rcsb pdb:2UYM|rcsb pdb:2WOG|rcsb pdb:2X2R|rcsb pdb:2X7C|rcsb pdb:2X7D|rcsb pdb:2X7E|rcsb pdb:2XAE|rcsb pdb:3CJO|rcsb pdb:3HQD|rcsb pdb:3K3B|rcsb pdb:3K5E|rcsb pdb:3KEN|rcsb pdb:3L9H|rcsb pdb:3WPN|rcsb pdb:3ZCW|rcsb pdb:4A1Z|rcsb pdb:4A28|rcsb pdb:4A50|rcsb pdb:4A51|rcsb pdb:4A5Y|rcsb pdb:4AP0|rcsb pdb:4AQV|rcsb pdb:4AQW|rcsb pdb:4AS7|rcsb pdb:4B7B|rcsb pdb:4BBG|rcsb pdb:4BXN|rcsb pdb:4CK5|rcsb pdb:4CK6|rcsb pdb:4CK7|rcsb pdb:4ZCA|rcsb pdb:4ZHI|rcsb pdb:5JV3|rcsb pdb:5ZO7|rcsb pdb:5ZO8|rcsb pdb:5ZO9|rcsb pdb:6G6Y|rcsb pdb:6G6Z|rcsb pdb:6HKX|rcsb pdb:6HKY|rcsb pdb:6TA3|rcsb pdb:6TA4|rcsb pdb:6TIW|rcsb pdb:6TLE|rcsb pdb:6TRL|rcsb pdb:6Y1I|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-53686N|genbank_protein_gi:13699824(identity)|refseq:NP_004514(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 1 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:YimbfuWYTSuyqgfs2RF8kCx2+xE9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P51659 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-358398|ensembl:ENSP00000424940|uniprotkb:B4DNV1|uniprotkb:B4DVS5|uniprotkb:E9PB82|uniprotkb:F5HE57 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:dhb4_human(display_long)|uniprotkb:HSD17B4(gene name)|psi-mi:HSD17B4(display_short)|uniprotkb:EDH17B4(gene name synonym)|uniprotkb:D-bifunctional protein(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 4(gene name synonym)|uniprotkb:Multifunctional protein 2(gene name synonym)|uniprotkb:SDR8C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 8C member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_000405.1|refseq:NP_001186220.1|refseq:NP_001186221.1|refseq:NP_001278956.1|refseq:NP_001278957.1|ensembl:ENSG00000133835(gene)|ensembl:ENST00000510025(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0033989"(3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity)|go:"GO:0036111"(very long-chain fatty-acyl-CoA metabolic process)|go:"GO:0036112"(medium-chain fatty-acyl-CoA metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0060009"(Sertoli cell development)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR002539(MaoC-like dehydratase)|interpro:IPR003033(Sterol-binding)|interpro:IPR020904|interpro:IPR029069|interpro:IPR036291|interpro:IPR036527|rcsb pdb:1IKT|rcsb pdb:1S9C|rcsb pdb:1ZBQ|rcsb pdb:6Z1W|rcsb pdb:6Z1X|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-390247|reactome:R-HSA-9033241|reactome:R-HSA-9033500|genbank_protein_gi:313482810(identity)|refseq:NP_001186220(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:i3A0dh9gAO2vfrCYXvo2U6+PwJQ9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P50990 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|genbank_protein_gi:48762932(identity)|refseq:NP_006576(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 10 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P48643 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|genbank_protein_gi:807066364(identity)|refseq:NP_001293084(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P46459 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2|genbank_protein_gi:310125280(identity)|refseq:NP_006169(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 19 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P42696 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2954772|ensembl:ENSP00000386226|uniprotkb:Q8N2Z8|uniprotkb:Q9H5A1|uniprotkb:A8K8J7 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:rbm34_human(display_long)|uniprotkb:RBM34(gene name)|psi-mi:RBM34(display_short)|uniprotkb:KIAA0117(gene name synonym)|uniprotkb:RNA-binding motif protein 34(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000188739(gene)|ensembl:ENST00000408888(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR034220|interpro:IPR034221|interpro:IPR035979|mint:P42696|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|refseq:NP_055829.2|refseq:NP_001333667.1|genbank_protein_gi:238859597(identity)|refseq:NP_055829(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:YrlnOTpyzg9F+4ZaZpLMfq4T4ts9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P26440 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2866408|uniprotkb:J3KR54|uniprotkb:Q53XZ9|uniprotkb:Q96AF6|uniprotkb:B2RCV5|uniprotkb:B3KVI7|ensembl:ENSP00000499074 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ivd_human(display_long)|uniprotkb:IVD(gene name)|psi-mi:IVD(display_short)|uniprotkb:Butyryl-CoA dehydrogenase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_002216.2|refseq:NP_001152980.1|ensembl:ENSG00000128928(gene)|ensembl:ENST00000651168(transcript)|go:"GO:0004085"(butyryl-CoA dehydrogenase activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0008470"(isovaleryl-CoA dehydrogenase activity)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042802"(identical protein binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034183|interpro:IPR036250|interpro:IPR037069|rcsb pdb:1IVH|reactome:R-HSA-70895|genbank_protein_gi:226958412(identity)|refseq:NP_002216(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:GewB1Yyc2EEVepN5e1H068xpjI09606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P23396 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N|genbank_protein_gi:15718687(identity)|refseq:NP_000996(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 21 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P19338 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226|genbank_protein_gi:189306(identity)|refseq:AAA59954(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P19320 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-6189824|ensembl:ENSP00000294728|uniprotkb:B4DKS4|uniprotkb:E9PDD1|uniprotkb:A8K6R7|uniprotkb:Q6NUP8 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:vcam1_human(display_long)|uniprotkb:VCAM1(gene name)|psi-mi:VCAM1(display_short)|uniprotkb:INCAM-100(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000162692(gene)|ensembl:ENST00000294728(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002102"(podosome)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005178"(integrin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0008131"(primary amine oxidase activity)|go:"GO:0009308"(amine metabolic process)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035094"(response to nicotine)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0005615"(extracellular space)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0045177"(apical part of cell)|go:"GO:0045471"(response to ethanol)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060384"(innervation)|go:"GO:0060945"(cardiac neuron differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071065"(alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0140039"(cell-cell adhesion in response to extracellular stimulus)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR003989(Vascular cell adhesion molecule-1)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|interpro:IPR008424(Immunoglobulin C2-set)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P19320|rcsb pdb:1IJ9|rcsb pdb:1VCA|rcsb pdb:1VSC|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-877300|interpro:IPR007110(Immunoglobulin-like)|refseq:NP_001069.1|refseq:NP_001186763.1|refseq:NP_542413.1|genbank_protein_gi:4507875(identity)|refseq:NP_001069(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 3 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:ZgZa+cLeZ2PxFhdxPut2qd7QHVo9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P18206 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_003364.1|refseq:NP_054706.1|ensembl:ENSG00000035403(gene)|ensembl:ENST00000211998(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002102"(podosome)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|go:"GO:0005198"(structural molecule activity)|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043297"(apical junction assembly)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048675"(axon extension)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0090636"(outer dense plaque of desmosome)|go:"GO:0090637"(inner dense plaque of desmosome)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904702"(regulation of protein localization to adherens junction)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990357"(terminal web)|interpro:IPR000633(Vinculin, conserved site)|ensembl:ENSP00000211998|ensembl:ENST00000372755|ensembl:ENSP00000361841|dip:DIP-35570N|genbank_protein_gi:119574932(identity)|refseq:EAW54547(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 1 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P14136 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|genbank_protein_gi:16265836(identity)|refseq:AAL16662(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P13639 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-352560|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001952.1|ensembl:ENSG00000167658(gene)|ensembl:ENST00000309311(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725|refseq:AAH24689(identity)|genbank_protein_gi:19353009(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P11387 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-876302|ensembl:ENSP00000354522|uniprotkb:Q15610|uniprotkb:Q5TFY3|uniprotkb:Q9UJN0|uniprotkb:O43256|uniprotkb:Q12855|uniprotkb:Q12856|uniprotkb:A8KA78|uniprotkb:E1P5W3 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:top1_human(display_long)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:TOP1(gene name)|psi-mi:TOP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000198900(gene)|ensembl:ENST00000361337(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0012501"(programmed cell death)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|refseq:NP_003277.1|dip:DIP-36356N|go:"GO:0032993"(protein-DNA complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042493"|go:"GO:0043204"(perikaryon)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|mint:P11387|rcsb pdb:1A31|rcsb pdb:1A35|rcsb pdb:1A36|rcsb pdb:1EJ9|rcsb pdb:1K4S|rcsb pdb:1K4T|rcsb pdb:1LPQ|rcsb pdb:1NH3|rcsb pdb:1R49|rcsb pdb:1RR8|rcsb pdb:1RRJ|rcsb pdb:1SC7|rcsb pdb:1SEU|rcsb pdb:1T8I|rcsb pdb:1TL8|reactome:R-HSA-4615885|genbank_protein_gi:28948850(identity)|refseq:1NH3_A(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 10 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:kB+3PVybgNp2mtOmDa7x8sygFuU9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P11142 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N|genbank_protein_gi:5729877(identity)|refseq:NP_006588(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 9 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P11021 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N|genbank_protein_gi:386758(identity)|refseq:AAA52614(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 8 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P0DMV8 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-11052499|uniprotkb:Q9UQM0|uniprotkb:Q5SP17|uniprotkb:Q5JQI4|uniprotkb:P08107|uniprotkb:B4E3B6|uniprotkb:Q9UQL9|uniprotkb:P19790|ensembl:ENSP00000364802|ensembl:ENSP00000382915|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:hs71a_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSX70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 1(gene name synonym)|uniprotkb:HSP72(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_005336.3|refseq:NP_005337.2|ensembl:ENSG00000204389(gene)|ensembl:ENSG00000215328(gene)|ensembl:ENSG00000234475(gene)|ensembl:ENSG00000235941(gene)|ensembl:ENSG00000237724(gene)|ensembl:ENST00000375651(transcript)|ensembl:ENST00000400040(transcript)|ensembl:ENST00000430065(transcript)|ensembl:ENST00000433487(transcript)|ensembl:ENST00000441618(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007041"(lysosomal transport)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031249"(denatured protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070370"(cellular heat acclimation)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0072562"(blood microparticle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902380"(positive regulation of endoribonuclease activity)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P0DMV8|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:2LMG|rcsb pdb:3A8Y|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|rcsb pdb:3Q49|rcsb pdb:4IO8|rcsb pdb:4J8F|rcsb pdb:4PO2|rcsb pdb:4WV5|rcsb pdb:4WV7|rcsb pdb:5AQW|rcsb pdb:5AQX|rcsb pdb:5AQY|rcsb pdb:5AQZ|rcsb pdb:5AR0|rcsb pdb:5BN8|rcsb pdb:5BN9|rcsb pdb:5BPL|rcsb pdb:5BPM|rcsb pdb:5BPN|rcsb pdb:5GJJ|rcsb pdb:5MKR|rcsb pdb:5MKS|rcsb pdb:5XI9|rcsb pdb:5XIR|rcsb pdb:6FHK|rcsb pdb:6G3R|rcsb pdb:6G3S|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-168330|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-450408|reactome:R-HSA-6798695|genbank_protein_gi:167466173(identity)|refseq:NP_005337(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 10 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:NFv4uj12xAWIr+OltarRlLDPr949606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P08238 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N|genbank_protein_gi:39644662(identity)|refseq:AAH09206(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 3 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P06748 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|genbank_protein_gi:119581852(identity)|refseq:EAW61448(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 18 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O76039 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1752465|uniprotkb:Q14198|uniprotkb:Q5H985|uniprotkb:Q8IYC7|uniprotkb:Q9UJL6|ensembl:ENSP00000485244|uniprotkb:G9B9X4 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:cdkl5_human(display_long)|uniprotkb:CDKL5(gene name)|psi-mi:CDKL5(display_short)|uniprotkb:STK9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000008086(gene)|ensembl:ENST00000623535(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016301"(kinase activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032839"(dendrite cytoplasm)|refseq:NP_001310218.1|refseq:NP_001032420.1|refseq:NP_003150.1|go:"GO:0036064"(ciliary basal body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0097542"(ciliary tip)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:4BGQ|genbank_protein_gi:4507281(identity)|refseq:NP_003150(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 1 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:jFecXdpQE+yBwqpPPU0ZGcnOheI9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O75928 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-348555|uniprotkb:O75927|uniprotkb:Q96BT5|uniprotkb:Q96KE3|ensembl:ENSP00000465676 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:pias2_human(display_long)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIASX(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_004662.2|refseq:NP_775298.1|refseq:NP_001310989.1|ensembl:ENSG00000078043(gene)|ensembl:ENST00000585916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027228|interpro:IPR036361|interpro:IPR038654|mint:O75928|rcsb pdb:2ASQ|rcsb pdb:4FO9|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-4090294|genbank_protein_gi:56699458(identity)|refseq:NP_004662(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 9 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:/7gObRzCbafNTNMKe8leGG/h2NQ9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O60826 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1|genbank_protein_gi:7661844(identity)|refseq:NP_054727(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 7 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O60447 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-852291|uniprotkb:A6NKX8|uniprotkb:Q9H1Y9|uniprotkb:B9A6J0|intact:EBI-28983653|ensembl:ENSP00000359356 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:evi5_human(display_long)|uniprotkb:Neuroblastoma stage 4S gene protein(gene name synonym)|uniprotkb:EVI5(gene name)|psi-mi:EVI5(display_short)|uniprotkb:NB4S(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_005656.4|ensembl:ENSP00000359356|ensembl:ENST00000540033|ensembl:ENSP00000440826|refseq:NP_001295177.1|dip:DIP-38024N|ensembl:ENSG00000067208(gene)|ensembl:ENST00000370331(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969|genbank_protein_gi:3095098(identity)|refseq:AAC16041(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 8 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:EyooNakM1gos/ADyryAHwuQPhZk9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O43395 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-744322|uniprotkb:O43446|uniprotkb:Q5VT54|uniprotkb:B4DSY9|intact:EBI-28983618|ensembl:ENSP00000315379 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:prpf3_human(display_long)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)|uniprotkb:U4/U6 snRNP 90 kDa protein(gene name synonym)|uniprotkb:PRPF3(gene name)|psi-mi:PRPF3(display_short)|uniprotkb:HPRP3(gene name synonym)|uniprotkb:PRP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_004689.1|ensembl:ENSP00000315379|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|interpro:IPR036483|mint:O43395|rcsb pdb:1X4Q|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|ensembl:ENSG00000117360(gene)|ensembl:ENST00000324862(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-34508N|genbank_protein_gi:4758556(identity)|refseq:NP_004689(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:Y2aO1gQjTU8JERVtrLpgbXq7nLU9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O43167 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-744471|uniprotkb:Q17RC6|uniprotkb:Q5TED5|uniprotkb:Q8N455|ensembl:ENSP00000230122 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:zbt24_human(display_long)|uniprotkb:Zinc finger protein 450(gene name synonym)|uniprotkb:ZBTB24(gene name)|psi-mi:ZBTB24(display_short)|uniprotkb:KIAA0441(gene name synonym)|uniprotkb:ZNF450(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001157785.1|refseq:NP_055612.2|ensembl:ENSG00000112365(gene)|ensembl:ENST00000230122(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O43167|interpro:IPR000210(BTB/POZ-like)|genbank_protein_gi:256600206(identity)|refseq:NP_055612(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 8 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:78JpKudyjkcnvRT5hMeTyp9rXnU9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O14744 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-351098|uniprotkb:Q6IBR1|uniprotkb:A8MZ91|uniprotkb:Q9UKH1|uniprotkb:B5BU10|uniprotkb:D3DS33|ensembl:ENSP00000319169|uniprotkb:A8MTP3|uniprotkb:B4DX49|uniprotkb:B4DY30|uniprotkb:E2QRE7 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:anm5_human(display_long)|uniprotkb:PRMT5(gene name)|psi-mi:PRMT5(display_short)|uniprotkb:IBP72(gene name synonym)|uniprotkb:JBP1(gene name synonym)|uniprotkb:HRMT1L5(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym)|uniprotkb:72 kDa ICln-binding protein(gene name synonym)|uniprotkb:SKB1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001034708.1|refseq:NP_006100.2|refseq:NP_001269882.1|refseq:NP_001269884.1|refseq:NP_001269885.1|ensembl:ENSG00000100462(gene)|ensembl:ENST00000324366(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0097421"(liver regeneration)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR025799|interpro:IPR029063|interpro:IPR035075|interpro:IPR035247|interpro:IPR035248|mint:O14744|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858|reactome:R-HSA-6804760|go:"GO:1904992"(positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway)|dip:DIP-33172N|genbank_protein_gi:20070220(identity)|refseq:NP_006100(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 8 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:EwePjCDiU/fiuKOO+wnoYQ8I57I9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O00571 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N|genbank_protein_gi:301171467(identity)|refseq:NP_001180345(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 7 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O00505 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276|genbank_protein_gi:119629243(identity)|refseq:EAX08838(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:D3DTH7 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404730 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:d3dth7_human(display_long)|uniprotkb:MYO1C(gene name)|psi-mi:MYO1C(display_short)|uniprotkb:hCG_28722(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0016459"(myosin complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036961|genbank_protein_gi:119611025(identity)|refseq:EAW90619(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:itPzNzrab9uJCfAjy/xZdQTXH6M9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:B3GQS7 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404728 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:b3gqs7_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:60 kDa heat shock protein, mitochondrial(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0005524"(ATP binding)|go:"GO:0009409"(response to cold)|go:"GO:0016853"(isomerase activity)|go:"GO:0042026"(protein refolding)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410|genbank_protein_gi:189502784(identity)|refseq:ACE06961(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 10 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:6dR9LqOyBr6cWqH+8sbBEZU2WDE9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:B0YJC5 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404726|ensembl:ENSP00000431702 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:b0yjc5_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000026025(gene)|ensembl:ENST00000469543(transcript)|go:"GO:0005882"(intermediate filament)|interpro:IPR018039|interpro:IPR027699|interpro:IPR039008|genbank_protein_gi:167887748(identity)|refseq:ACA06100(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 21 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:Ls3ukUJRWNiLkqZmSFnbbANOl+w9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:A8MW92 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2560834|uniprotkb:Q9H702|uniprotkb:Q86W43|uniprotkb:A8MZC9|uniprotkb:Q96BT0|uniprotkb:Q9HBK3|uniprotkb:Q9NYR3|uniprotkb:Q9Y381|intact:EBI-2797510|uniprotkb:Q86U89|ensembl:ENSP00000378784|ensembl:ENSP00000482945 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:p20l1_human(display_long)|uniprotkb:PHF20L1(gene name)|psi-mi:PHF20L1(display_short)|uniprotkb:CGI-72(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_057102.4|refseq:NP_940915.1|ensembl:ENSG00000129292(gene)|ensembl:ENST00000395386(transcript)|ensembl:ENST00000622263(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR002999(Tudor)|interpro:IPR004092(Mbt repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014002(Tudor-like, plant)|interpro:IPR019786|interpro:IPR022255|interpro:IPR040477|interpro:IPR043449|mint:A8MW92|rcsb pdb:2EQM|rcsb pdb:2EQU|rcsb pdb:2JTF|rcsb pdb:6L10|rcsb pdb:6L1C|rcsb pdb:6L1F|rcsb pdb:6L1I|rcsb pdb:6L1P|rcsb pdb:6L0X|refseq:XP_016869006.1|genbank_protein_gi:39653325(identity)|refseq:NP_940915(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 18 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:rkzmf0OHtpMATZ2P0uhZu0GR94E9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:A6NK53 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2689072|uniprotkb:B2RN78|uniprotkb:B2RN79|uniprotkb:Q86WL8|ensembl:ENSP00000375820|ensembl:ENSP00000507588 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:zn233_human(display_long)|uniprotkb:ZNF233(gene name)|psi-mi:ZNF233(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001193934.1|refseq:NP_861421.2|ensembl:ENSG00000159915(gene)|ensembl:ENST00000391958(transcript)|ensembl:ENST00000683810(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|genbank_protein_gi:32308169(identity)|refseq:NP_861421(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 7 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:NaxB47UVUZPjAoBgDr9pvW91c2w9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:A6NI56 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-11898885|intact:EBI-28973211|uniprotkb:G9JV18 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:cc154_human(display_long)|uniprotkb:CCDC154(gene name)|psi-mi:CCDC154(display_short)|uniprotkb:C16orf29(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0005769"(early endosome)|go:"GO:0035630"(bone mineralization involved in bone maturation)|interpro:IPR029512|refseq:NP_001137452.1|genbank_protein_gi:215277041(identity)|refseq:A6NI56(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 6 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:WogCJGpVkr4h2h4iUPcTtfmpkhA9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:A5YP36 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404724 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:a5yp36_human(display_long)|uniprotkb:SEC15L3(gene name)|psi-mi:SEC15L3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0000145"(exocyst)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR042044|interpro:IPR042045|interpro:IPR007225(Exocyst complex subunit Sec15-like)|refseq:NP_001306129.1|genbank_protein_gi:148608033(identity)|refseq:ABQ95573(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 5 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:6/MvAyzMwFWuDLX7wCGYAbT5Mo09606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:A0A024R0Q3 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404722 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:a0a024r0q3_human(display_long)|uniprotkb:ZNF224(gene name)|psi-mi:ZNF224(display_short)|uniprotkb:hCG_1647772(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14404759|imex:IM-25425-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|genbank_protein_gi:119577656(identity)|refseq:EAW57252(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 3 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2020/10/21 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:b4ZsQLia6Z1fuvCuQkkPiyeHg4o9606 rigid:DqOKCpPsSI3zQGyF4QBe6qPN+Xc false flag tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q92878 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-495494|uniprotkb:O43254|uniprotkb:Q6GMT7|uniprotkb:Q6P5X3|uniprotkb:Q9UP86|uniprotkb:B9EGF5|ensembl:ENSP00000368100 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:rad50_human(display_long)|uniprotkb:RAD50(gene name)|psi-mi:RAD50(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_005723.2|dip:DIP-33606N|ensembl:ENSG00000113522(gene)|ensembl:ENST00000378823(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR013134(Zinc hook, Rad50)|interpro:IPR027417|interpro:IPR038729|mint:Q92878|rcsb pdb:5GOX|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR004584(Recombination/repair protein Rad50)|genbank_protein_gi:49256867(identity)|refseq:AAH73850(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 7 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:yZsT5GcpA9HeFMoK4Jb1HYhrdKQ9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9Y592 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-8600408|ensembl:ENSP00000344655|ensembl:ENSP00000380911|intact:MINT-1790539|uniprotkb:A4FVB1|uniprotkb:Q08AP1 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:cep83_human(display_long)|uniprotkb:CEP83(gene name)|psi-mi:CEP83(display_short)|uniprotkb:CCDC41(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 41(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-58(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000173588(gene)|ensembl:ENST00000339839(transcript)|ensembl:ENST00000397809(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR029631|reactome:R-HSA-5620912|refseq:NP_057206.2|refseq:NP_001035858.1|refseq:NP_001333386.1|refseq:XP_011536726.1|refseq:XP_016874874.1|refseq:XP_016874875.1|genbank_protein_gi:133778259(identity)|refseq:AAI25087(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:mint|comment:This prey was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:mPL1YHgAG3ezc1qfYM7QkGa0rps9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96QL0 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-8456461|intact:MINT-4934930 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q96ql0_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|refseq:NP_001029025.1|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR000597(Ribosomal protein L3)|genbank_protein_gi:14250148(identity)|refseq:AAH08492(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 14 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:EnPwbNjlPAa+l6qOghPhXP1b8jc9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P43304 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-7600203|uniprotkb:Q59FR1|intact:MINT-4530883|uniprotkb:Q9HAP9|uniprotkb:A8K4V0|uniprotkb:B3KSA9|ensembl:ENSP00000308610|ensembl:ENSP00000386425|ensembl:ENSP00000386626|ensembl:ENSP00000409708 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:gpdm_human(display_long)|uniprotkb:GPD2(gene name)|psi-mi:GPD2(display_short)|uniprotkb:mtGPD(gene name synonym)|uniprotkb:mitohondrial glycerophosphate dehydrogenase gene(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:XP_016859319.1|refseq:XP_011509279.1|refseq:NP_001076581.2|refseq:NP_000399.3|refseq:XP_005246526.1|ensembl:ENSG00000115159(gene)|ensembl:ENST00000310454(transcript)|ensembl:ENST00000409674(transcript)|ensembl:ENST00000409861(transcript)|ensembl:ENST00000438166(transcript)|go:"GO:0004368"("glycerol-3-phosphate dehydrogenase (quinone) activity")|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006127"(glycerophosphate shuttle)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0052591"("sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity")|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR031656|interpro:IPR036188|interpro:IPR038299|reactome:R-HSA-1483166|reactome:R-HSA-163560|genbank_protein_gi:285002231(identity)|refseq:NP_001076581(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:mint|comment:homomint|comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:PsG9Eo7dfk8l+vDJl6d4WfEST849606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:A8K979 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-7851226|uniprotkb:Q9P224|intact:MINT-6782974|uniprotkb:Q6ZSJ2|uniprotkb:Q9Y6V3|uniprotkb:Q96FR9|ensembl:ENSP00000350651 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:eri2_human(display_long)|uniprotkb:KIAA1504(gene name synonym)|uniprotkb:EXOD1(gene name synonym)|uniprotkb:Exonuclease domain-containing protein 1(gene name synonym)|uniprotkb:ERI2(gene name)|psi-mi:ERI2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_542394.2|refseq:NP_001136197.1|ensembl:ENSG00000196678(gene)|ensembl:ENST00000357967(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003676"(nucleic acid binding)|go:"GO:0008270"(zinc ion binding)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036397|genbank_protein_gi:168270578(identity)|refseq:BAG10082(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:mint|comment:homomint|comment:This prey was identified in band no. 14 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:BgKGsn/h7suuW9TajU4/GsqkSgo9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P78324 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-745147|uniprotkb:O00683|uniprotkb:O43799|uniprotkb:Q8N517|uniprotkb:Q8TAL8|uniprotkb:Q9H0Z2|uniprotkb:Q9UDX2|uniprotkb:Q9UIJ6|uniprotkb:Q9Y4U9|uniprotkb:A8K411|uniprotkb:A2A2E1|ensembl:ENSP00000348307|ensembl:ENSP00000351621|ensembl:ENSP00000382941|uniprotkb:B2R6C3 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:shps1_human(display_long)|uniprotkb:Inhibitory receptor SHPS-1(gene name synonym)|uniprotkb:Signal-regulatory protein alpha-1(gene name synonym)|uniprotkb:Signal-regulatory protein alpha-2(gene name synonym)|uniprotkb:Signal-regulatory protein alpha-3(gene name synonym)|uniprotkb:MyD-1 antigen(gene name synonym)|uniprotkb:Brain Ig-like molecule with tyrosine-based activation motifs(gene name synonym)|uniprotkb:Macrophage fusion receptor(gene name synonym)|uniprotkb:p84(gene name synonym)|uniprotkb:CD172 antigen-like family member A(gene name synonym)|uniprotkb:SIRPA(gene name)|psi-mi:SIRPA(display_short)|uniprotkb:BIT(gene name synonym)|uniprotkb:MFR(gene name synonym)|uniprotkb:MYD1(gene name synonym)|uniprotkb:SHPS1(gene name synonym)|uniprotkb:SIRP(gene name synonym)|uniprotkb:PTPNS1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001035111.1|refseq:NP_001035112.1|refseq:NP_542970.1|ensembl:ENSG00000198053(gene)|ensembl:ENST00000356025(transcript)|ensembl:ENST00000358771(transcript)|ensembl:ENST00000400068(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0035696"(monocyte extravasation)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071349"(cellular response to interleukin-12)|go:"GO:0071641"(negative regulation of macrophage inflammatory protein 1 alpha production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1903720"(negative regulation of I-kappaB phosphorylation)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2JJS|rcsb pdb:2JJT|rcsb pdb:2UV3|rcsb pdb:2WNG|rcsb pdb:4CMM|rcsb pdb:6BIT|rcsb pdb:6NMR|rcsb pdb:6NMS|rcsb pdb:6NMT|rcsb pdb:6NMU|rcsb pdb:6NMV|rcsb pdb:7KPG|reactome:R-HSA-202733|reactome:R-HSA-391160|reactome:R-HSA-6798695|refseq:XP_005260727.1|refseq:NP_001317657.1|genbank_protein_gi:18426911(identity)|refseq:NP_542970(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:6Zacoq8Ycjy9+cn3gge8ZUZGGvE9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9Y6K8 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-718680|uniprotkb:Q96EC9|uniprotkb:Q6FH66|uniprotkb:Q5U622|uniprotkb:Q7Z4T5|uniprotkb:Q86YS0|uniprotkb:Q8N464|ensembl:ENSP00000346577 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:kad5_human(display_long)|uniprotkb:ATP-AMP transphosphorylase 5(gene name synonym)|uniprotkb:AK5(gene name)|psi-mi:AK5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_036225.2|refseq:NP_777283.1|refseq:XP_006710635.1|ensembl:ENSG00000154027(gene)|ensembl:ENST00000354567(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0006173"(dADP biosynthetic process)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0009220"(pyrimidine ribonucleotide biosynthetic process)|go:"GO:0034451"(centriolar satellite)|go:"GO:0046034"(ATP metabolic process)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006267(Adenylate kinase, isozyme 1)|interpro:IPR027417|interpro:IPR033690|rcsb pdb:2BWJ|reactome:R-HSA-499943|refseq:XP_016856497.1|refseq:XP_016856498.1|genbank_protein_gi:22477787(identity)|refseq:AAH36666(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 7 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:nJ7VUwrjX0Udx+rTI6bjAk5nA6E9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9Y5K6 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-298152|uniprotkb:A6NL34|uniprotkb:Q5VYA3|uniprotkb:Q9UG97|ensembl:ENSP00000352264 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:cd2ap_human(display_long)|uniprotkb:CD2AP(gene name)|psi-mi:CD2AP(display_short)|uniprotkb:Cas ligand with multiple SH3 domains(gene name synonym)|uniprotkb:Adapter protein CMS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000198087(gene)|ensembl:ENST00000359314(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031941"(filamentous actin)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9Y5K6|rcsb pdb:2FEI|rcsb pdb:2J6F|rcsb pdb:2J6K|rcsb pdb:2J6O|rcsb pdb:2J7I|rcsb pdb:3AA6|rcsb pdb:3LK4|rcsb pdb:3U23|rcsb pdb:4WCI|rcsb pdb:4X1V|rcsb pdb:7DS6|rcsb pdb:7DS8|reactome:R-HSA-373753|refseq:NP_036252.1|dip:DIP-31807N|genbank_protein_gi:11321634(identity)|refseq:NP_036252(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:T0OYMq1jOCwVMJOxnrPg5Jm4CGw9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9Y5B0 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2807555|ensembl:ENSP00000484525|uniprotkb:Q9Y6F5|uniprotkb:Q7Z644|uniprotkb:Q96BZ1|uniprotkb:A8MY97 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ctdp1_human(display_long)|uniprotkb:CTDP1(gene name)|psi-mi:CTDP1(display_short)|uniprotkb:FCP1(gene name synonym)|uniprotkb:TFIIF-associating CTD phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000060069(gene)|ensembl:ENST00000613122(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0030496"(midbody)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR001357(BRCT)|interpro:IPR004274(NLI interacting factor)|interpro:IPR011947(FCP1-like phosphatase, phosphatase domain)|interpro:IPR015388(FCP1-like phosphatase, C-terminal)|interpro:IPR023214|interpro:IPR036412|interpro:IPR036420|interpro:IPR039189|rcsb pdb:1J2X|rcsb pdb:1ONV|rcsb pdb:2K7L|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_001189433.1|refseq:NP_004706.3|refseq:NP_430255.2|dip:DIP-41788N|genbank_protein_gi:321267522(identity)|refseq:NP_001189433(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:LEqMeYJjhIWOx3RZtX3ljR5IZS49606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9Y240 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-3957044|uniprotkb:B2RAD4|ensembl:ENSP00000250340 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:clc11_human(display_long)|uniprotkb:CLEC11A(gene name)|psi-mi:CLEC11A(display_short)|uniprotkb:CLECSF3(gene name synonym)|uniprotkb:LSLCL(gene name synonym)|uniprotkb:SCGF(gene name synonym)|uniprotkb:C-type lectin superfamily member 3(gene name synonym)|uniprotkb:Lymphocyte secreted C-type lectin(gene name synonym)|uniprotkb:Stem cell growth factor(gene name synonym)|uniprotkb:p47(gene name synonym)|uniprotkb:Osteolectin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030246"(carbohydrate binding)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|ensembl:ENSG00000105472(gene)|ensembl:ENST00000250340(transcript)|go:"GO:0001503"(ossification)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|refseq:NP_002966.1|genbank_protein_gi:4506803(identity)|refseq:NP_002966(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 16 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:kz8Kt2JUxILa9BZzB34WYKi+Hhw9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9UJS0 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1222503|uniprotkb:O14566|uniprotkb:O14575|uniprotkb:Q9NZW1|uniprotkb:Q9UNI7|uniprotkb:Q546F9|ensembl:ENSP00000265631 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:cmc2_human(display_long)|uniprotkb:SLC25A13(gene name)|psi-mi:SLC25A13(display_short)|uniprotkb:ARALAR2(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 13(gene name synonym)|uniprotkb:Citrin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_055066.1|refseq:NP_001153682.1|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0009066"(aspartate family amino acid metabolic process)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045333"(cellular respiration)|go:"GO:0051592"(response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR023395|interpro:IPR029658|mint:Q9UJS0|rcsb pdb:4P5W|reactome:R-HSA-1268020|reactome:R-HSA-70263|reactome:R-HSA-8963693|ensembl:ENSG00000004864(gene)|ensembl:ENST00000265631(transcript)|genbank_protein_gi:7657581(identity)|refseq:NP_055066(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 10 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:YtrKzkRujsJ/hzl2bJaLgJAAswI9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9P2J8 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-9116427|uniprotkb:Q3SY62|uniprotkb:Q3SY63|uniprotkb:Q6ZN27|ensembl:ENSP00000310472 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:zn624_human(display_long)|uniprotkb:ZNF624(gene name)|psi-mi:ZNF624(display_short)|uniprotkb:KIAA1349(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_065838.2|refseq:XP_006721625.1|ensembl:ENSG00000197566(gene)|ensembl:ENST00000311331(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|genbank_protein_gi:74355161(identity)|refseq:AAI03947(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 6 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:YD70e/DBZ+Jax/+t26vf/KxyJ9k9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9NSY0 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-11145350|uniprotkb:Q597G7|uniprotkb:Q8NCX8|uniprotkb:Q2HIX8|uniprotkb:B4DF59|uniprotkb:Q8WYS5|ensembl:ENSP00000414055 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:nrbp2_human(display_long)|uniprotkb:NRBP2(gene name)|psi-mi:NRBP2(display_short)|uniprotkb:Transformation-related gene 16 protein(gene name synonym)|uniprotkb:PP9320(orf name)|uniprotkb:TRG16(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_848659.2|ensembl:ENSG00000185189(gene)|ensembl:ENST00000442628(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR042697|genbank_protein_gi:33415065(identity)|refseq:AAQ18040(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 8 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:/eAUv+e8cD6i+5KprqUsP3eRrG09606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9NQZ5 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-4402938|uniprotkb:D3DXG9|uniprotkb:Q53T44|uniprotkb:Q6GU43|uniprotkb:Q969M6|ensembl:ENSP00000338030 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:star7_human(display_long)|uniprotkb:STARD7(gene name)|psi-mi:STARD7(display_short)|uniprotkb:GTT1(gene name synonym)|uniprotkb:Gestational trophoblastic tumor protein 1(gene name synonym)|uniprotkb:START domain-containing protein 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_064536.2|ensembl:ENSG00000084090(gene)|ensembl:ENST00000337288(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008289"(lipid binding)|interpro:IPR002913(Lipid-binding START)|interpro:IPR023393|interpro:IPR041949|reactome:R-HSA-1483191|genbank_protein_gi:151301035(identity)|refseq:NP_064536(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 20 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:IumLsd1b+hqnlC9WmBLpXjGXmLs9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9NPB1 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14405246|ensembl:ENSP00000373674 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:nt5m_human(display_long)|uniprotkb:NT5M(gene name)|psi-mi:NT5M(display_short)|uniprotkb:DNT2(gene name synonym)|uniprotkb:Deoxy-5'-nucleotidase 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000205309(gene)|ensembl:ENST00000389022(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006260"(DNA replication)|go:"GO:0008252"(nucleotidase activity)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009223"(pyrimidine deoxyribonucleotide catabolic process)|go:"GO:0046079"(dUMP catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR010708(5 nucleotidase, deoxy, cytosolic type C)|interpro:IPR023214|interpro:IPR036412|rcsb pdb:1MH9|rcsb pdb:1Q91|rcsb pdb:1Q92|rcsb pdb:1Z4I|rcsb pdb:1Z4J|rcsb pdb:1Z4K|rcsb pdb:1Z4L|rcsb pdb:1Z4M|rcsb pdb:1Z4P|rcsb pdb:1Z4Q|rcsb pdb:2JAU|rcsb pdb:2JAW|rcsb pdb:4L6A|rcsb pdb:4L6C|rcsb pdb:4MUM|rcsb pdb:4MWO|rcsb pdb:4NFL|rcsb pdb:4YIK|rcsb pdb:6G22|rcsb pdb:6G2L|rcsb pdb:6G2M|reactome:R-HSA-73621|refseq:NP_064586.1|genbank_protein_gi:73535804(identity)|refseq:1Z4I_A(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 19 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:NTr4sW09l/JWuDFwur0l550R/Ow9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9H7E2 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-3938232|uniprotkb:Q6P992|uniprotkb:B2MWP9|uniprotkb:Q53XA6|ensembl:ENSP00000196169|ensembl:ENSP00000367126|ensembl:ENSP00000498191 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:tdrd3_human(display_long)|uniprotkb:TDRD3(gene name)|psi-mi:TDRD3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000083544(gene)|ensembl:ENST00000196169(transcript)|ensembl:ENST00000377894(transcript)|ensembl:ENST00000648252(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0035064"(methylated histone binding)|interpro:IPR002999(Tudor)|interpro:IPR009060(UBA-like)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR041915|interpro:IPR042470|mint:Q9H7E2|rcsb pdb:1WJI|rcsb pdb:2LTO|rcsb pdb:3PMT|rcsb pdb:3PNW|rcsb pdb:3S6W|rcsb pdb:5GVD|rcsb pdb:5GVE|rcsb pdb:5YJ8|rcsb pdb:6V9T|refseq:NP_001139542.1|refseq:NP_001139543.1|refseq:NP_110421.1|refseq:XP_016876266.1|dip:DIP-61935N|genbank_protein_gi:38174568(identity)|refseq:AAH60876(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 6 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:Fao3X109d50ZnSif4TMnx/seheA9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9H2D6 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-715619|uniprotkb:B1AHD4|uniprotkb:B1AHD7|uniprotkb:O94797|uniprotkb:Q2PZW8|uniprotkb:Q2Q3Z9|uniprotkb:Q2Q400|uniprotkb:Q5R3M6|uniprotkb:Q96DW1|uniprotkb:Q9BT77|uniprotkb:Q9BTL7|uniprotkb:Q9BY98|uniprotkb:Q9Y3L4|ensembl:ENSP00000496394|intact:EBI-2560917|uniprotkb:F2Z2W0|uniprotkb:F8W6V6 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:tara_human(display_long)|uniprotkb:Protein Tara(gene name synonym)|uniprotkb:Trio-associated repeat on actin(gene name synonym)|uniprotkb:TRIOBP(gene name)|psi-mi:TRIOBP(display_short)|uniprotkb:KIAA1662(gene name synonym)|uniprotkb:TARA(gene name synonym)|uniprotkb:HRIHFB2122(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001034230.1|refseq:NP_008963.3|refseq:NP_619538.2|ensembl:ENSG00000100106(gene)|ensembl:ENST00000644935(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030047"(actin modification)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045159"(myosin II binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051301"(cell division)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|mint:Q9H2D6|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|genbank_protein_gi:13177667(identity)|refseq:AAH03618(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 7 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:2evioSQxAnH1x5VPGsZyK+fJTY09606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9BZ63 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14405244 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q9bz63_human(display_long)|uniprotkb:FKSG60(gene name)|psi-mi:FKSG60(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) genbank_protein_gi:62088454(identity)|refseq:BAD92674(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 19 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:gONgu9l6XAWS8EUu+V0I75xDJS09606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9BX69 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14405242|ensembl:ENSP00000254691|uniprotkb:Q52LR2 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:card6_human(display_long)|uniprotkb:CARD6(gene name)|psi-mi:CARD6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000132357(gene)|ensembl:ENST00000254691(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|refseq:NP_115976.2|dip:DIP-61097N|genbank_protein_gi:62089274(identity)|refseq:NP_115976(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 1 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:yV0IAFGVkhqPs4V4wah7p3gJd589606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9BUP3 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-13625358|ensembl:ENSP00000387876|ensembl:ENSP00000394259|ensembl:ENSP00000397752|uniprotkb:A8K7S7|uniprotkb:D3DQY8|uniprotkb:O15383|uniprotkb:O60520|uniprotkb:O95345|uniprotkb:Q53GC1|uniprotkb:Q53GG2|uniprotkb:Q6IBI3 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:htai2_human(display_long)|uniprotkb:HTATIP2(gene name)|psi-mi:HTATIP2(display_short)|uniprotkb:30 kDa HIV-1 TAT-interacting protein(gene name synonym)|uniprotkb:CC3(gene name synonym)|uniprotkb:HIV-1 TAT-interactive protein 2(gene name synonym)|uniprotkb:TIP30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000109854(gene)|ensembl:ENST00000421577(transcript)|ensembl:ENST00000443524(transcript)|ensembl:ENST00000451739(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051170"(import into nucleus)|interpro:IPR016040("NAD(P)-binding")|interpro:IPR036291|rcsb pdb:2BKA|refseq:NP_001091990.1|refseq:NP_001091991.1|refseq:NP_001091992.1|refseq:NP_001091993.1|refseq:NP_006401.3|genbank_protein_gi:119588747(identity)|refseq:EAW68341(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 19 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:QbLj0k3EWp4OjupRpDV0eLZHpY09606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q9BQA1 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_077007.1|refseq:NP_001303991.1|refseq:NP_001303992.1|refseq:NP_001303993.1|dip:DIP-38172N|ensembl:ENSG00000116455(gene)|ensembl:ENST00000235090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0034709"(methylosome)|go:"GO:0045495"(pole plasm)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858|genbank_protein_gi:14495615(identity)|refseq:AAH09411(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 17 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:0q4wunYtHalObC8r1wphhelIpr49606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96RE1 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14405240 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q96re1_human(display_long)|uniprotkb:EEF1A1L14(gene name)|psi-mi:EEF1A1L14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|genbank_protein_gi:15277711(identity)|refseq:AAK93966(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 14 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:gISZi0wZ4qn3UsqfmfccwvL01+09606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96PP8 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)|genbank_protein_gi:37183024(identity)|refseq:AAQ89312(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96M69 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-9478535|uniprotkb:Q2M3I1|ensembl:ENSP00000285928 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:lrguk_human(display_long)|uniprotkb:LRGUK(gene name)|psi-mi:LRGUK(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_653249.1|interpro:IPR027417|interpro:IPR032675|ensembl:ENSG00000155530(gene)|ensembl:ENST00000285928(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0035082"(axoneme assembly)|go:"GO:0042995"(cell projection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|genbank_protein_gi:21389483(identity)|refseq:NP_653249(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:Jb5TslAs9nplbT4CAmvObB9F2Qg9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96JE9 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-9316441|uniprotkb:A7E2A1|uniprotkb:Q6P3T0|uniprotkb:Q6ZWB8|ensembl:ENSP00000307093 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:map6_human(display_long)|uniprotkb:MAP6(gene name)|psi-mi:MAP6(display_short)|uniprotkb:KIAA1878(gene name synonym)|uniprotkb:Stable tubule-only polypeptide(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_149052.1|refseq:NP_997460.1|ensembl:ENSG00000171533(gene)|ensembl:ENST00000304771(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR007882(STOP)|genbank_protein_gi:39795300(identity)|refseq:AAH63860(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 7 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:azKypJOoIZuTldplWlQYh7Ebb3I9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96I65 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-877770 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q96i65_human(display_long)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|refseq:NP_937884.1|refseq:NP_937887.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR037584|interpro:IPR016021(MIF4-like, type 1/2/3)|genbank_protein_gi:14043628(identity)|refseq:AAH07788(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 8 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:tyvFLXtRA/TeKF7MlwKJwnzIgYY9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96I23 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14405238|ensembl:ENSP00000273968|uniprotkb:B2R571 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:prey_human(display_long)|uniprotkb:PYURF(gene name)|psi-mi:PYURF(display_short)|uniprotkb:PIGY upstream reading frame protein(gene name synonym)|uniprotkb:PREY(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENST00000273968(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0009893"(positive regulation of metabolic process)|interpro:IPR005651(Protein of unknown function DUF343)|ensembl:ENSG00000145337(gene)|refseq:NP_116295.1|genbank_protein_gi:14249680(identity)|refseq:NP_116295(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 18 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:TsJxSXakXoE9a/ldulq+YMotTrQ9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96DZ5 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-12823145|ensembl:ENSP00000353732|ensembl:ENSP00000466832|uniprotkb:A8K0E4|uniprotkb:Q8WWL1|uniprotkb:Q96C99|uniprotkb:Q9UFT7 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:clip3_human(display_long)|uniprotkb:CLIP3(gene name)|psi-mi:CLIP3(display_short)|uniprotkb:CLIPR59(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170-related 59 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000105270(gene)|ensembl:ENST00000360535(transcript)|ensembl:ENST00000593074(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005795"(Golgi stack)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008017"(microtubule binding)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035594"(ganglioside binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044091"(membrane biogenesis)|go:"GO:0045121"(membrane raft)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR030504|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2CP0|reactome:R-HSA-5357905|refseq:NP_001186499.1|refseq:NP_056341.1|genbank_protein_gi:62913997(identity)|refseq:AAH14486(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:QAYtmmtdFjr4mRHn3cfJhw+8JCY9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q96AX2 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-748121|uniprotkb:A8MXF5|uniprotkb:A8MYT0|uniprotkb:Q8IWA7|ensembl:ENSP00000376389|ensembl:ENSP00000436563|ensembl:ENSP00000483155 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:rab37_human(display_long)|uniprotkb:RAB37(gene name)|psi-mi:RAB37(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001006639.1|refseq:NP_001157461.1|refseq:NP_001157462.1|refseq:NP_783865.1|refseq:NP_001317400.1|ensembl:ENSG00000172794(gene)|ensembl:ENST00000392613(transcript)|ensembl:ENST00000481224(transcript)|ensembl:ENST00000613645(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-HSA-6798695|reactome:R-HSA-8873719|genbank_protein_gi:28376635(identity)|refseq:NP_783865(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 19 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:hXcRUHYbbCGiJhkLFTSrri04Uys9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8TE49 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1049564|uniprotkb:Q8IWK5|ensembl:ENSP00000453883|ensembl:ENSP00000503326 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:otu7a_human(display_long)|uniprotkb:Zinc finger protein Cezanne 2(gene name synonym)|uniprotkb:OTUD7A(gene name)|psi-mi:OTUD7A(display_short)|uniprotkb:C15orf16(gene name synonym)|uniprotkb:OTUD7(gene name synonym)|uniprotkb:CEZANNE2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_570971.1|ensembl:ENSG00000169918(gene)|ensembl:ENST00000560598(transcript)|ensembl:ENST00000678495(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035871"(protein K11-linked deubiquitination)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR033477|rcsb pdb:2L2D|reactome:R-HSA-5689896|genbank_protein_gi:119581673(identity)|refseq:EAW61269(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 18 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:wNCKAjekqmd8vNwl0fmq/KA/Tck9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8TDX6 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-13624785|ensembl:ENSP00000330805|ensembl:ENSP00000411816|ensembl:ENSP00000429809|uniprotkb:B2RBE4|uniprotkb:Q6P9G6|uniprotkb:Q8IUF9|uniprotkb:Q9NSQ7|uniprotkb:Q9NUM9 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:cgat1_human(display_long)|uniprotkb:CSGALNACT1(gene name)|psi-mi:CSGALNACT1(display_short)|uniprotkb:CHGN(gene name synonym)|uniprotkb:Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1(gene name synonym)|uniprotkb:GALNACT1(gene name synonym)|uniprotkb:UNQ656/PRO1287(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000147408(gene)|ensembl:ENST00000332246(transcript)|ensembl:ENST00000454498(transcript)|ensembl:ENST00000522854(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0008376"(acetylgalactosaminyltransferase activity)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0015014"(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|go:"GO:0015020"(glucuronosyltransferase activity)|go:"GO:0019276"(UDP-N-acetylgalactosamine metabolic process)|go:"GO:0030166"(proteoglycan biosynthetic process)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0030210"(heparin biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046398"(UDP-glucuronate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047237"(glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity)|go:"GO:0047238"(glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity)|go:"GO:0050650"(chondroitin sulfate proteoglycan biosynthetic process)|go:"GO:0050651"(dermatan sulfate proteoglycan biosynthetic process)|go:"GO:0050653"(chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|interpro:IPR008428(Chondroitin N-acetylgalactosaminyltransferase)|interpro:IPR029044|reactome:R-HSA-2022870|refseq:NP_001123990.1|refseq:NP_060841.5|refseq:XP_006716421.1|refseq:XP_006716422.1|refseq:XP_006716423.1|refseq:XP_006716424.1|refseq:XP_006716425.1|refseq:XP_006716426.1|refseq:XP_006716427.1|refseq:XP_011542880.1|refseq:XP_011542881.1|refseq:XP_011542882.1|refseq:XP_011542884.1|refseq:XP_011542885.1|refseq:XP_011542886.1|refseq:XP_016869112.1|refseq:XP_016869113.1|refseq:XP_016869114.1|refseq:XP_016869115.1|refseq:XP_016869116.1|refseq:XP_016869117.1|refseq:XP_016869118.1|refseq:XP_016869119.1|refseq:XP_016869120.1|refseq:XP_016869121.1|refseq:XP_016869122.1|refseq:XP_016869123.1|refseq:XP_016869124.1|refseq:XP_016869125.1|refseq:XP_016869126.1|refseq:XP_016869127.1|genbank_protein_gi:22852208(identity)|refseq:BAC16217(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 10 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:ugP4FQvGmOFCz5becwPh+iiJPYU9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8NE79 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-6872429|ensembl:ENSP00000313172|ensembl:ENSP00000337259|ensembl:ENSP00000397310|uniprotkb:E1P5D8|uniprotkb:Q9HBV0|uniprotkb:Q5T550|uniprotkb:A8K1R4|uniprotkb:Q5T551|uniprotkb:Q8IWC6|uniprotkb:Q9UNG6 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:popd1_human(display_long)|uniprotkb:POP1(gene name synonym)|uniprotkb:POPDC1(gene name synonym)|uniprotkb:Popeye domain-containing protein 1(gene name synonym)|uniprotkb:BVES(gene name)|psi-mi:BVES(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:XP_011533700.1|ensembl:ENSG00000112276(gene)|ensembl:ENST00000314641(transcript)|ensembl:ENST00000336775(transcript)|ensembl:ENST00000446408(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|interpro:IPR006916(Popeye protein conserved region)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|go:"GO:0005198"(structural molecule activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030552"(cAMP binding)|go:"GO:0031253"(cell projection membrane)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048278"(vesicle docking)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0060973"(cell migration involved in heart development)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:2001135"(regulation of endocytic recycling)|refseq:NP_001186492.1|refseq:NP_009004.2|refseq:NP_671488.1|genbank_protein_gi:5802788(identity)|refseq:AAD51780(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 18 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:uMa+wxSNuiMuP5kfLgQg2NgJkko9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8ND71 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2824826|ensembl:ENSP00000305107|uniprotkb:A0A090N8H2 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:gima8_human(display_long)|uniprotkb:GIMAP8(gene name)|psi-mi:GIMAP8(display_short)|uniprotkb:IAN9(gene name synonym)|uniprotkb:IANT(gene name synonym)|uniprotkb:Immune-associated nucleotide-binding protein 9(gene name synonym)|uniprotkb:Protein IanT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000171115(gene)|ensembl:ENST00000307271(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0070232"(regulation of T cell apoptotic process)|interpro:IPR006703(AIG1)|interpro:IPR027417|refseq:NP_783161.1|refseq:XP_005250007.1|genbank_protein_gi:28416956(identity)|refseq:NP_783161(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 7 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:vDWdNOF9z1nfhrz8Yx/ONT8EyqM9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8N4X5 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-11310376|uniprotkb:Q96PX4|uniprotkb:Q96SY5|uniprotkb:Q2UZW3|uniprotkb:A8K6P7|uniprotkb:B3KVQ8|uniprotkb:Q8TB54|ensembl:ENSP00000303042 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:af1l2_human(display_long)|uniprotkb:AFAP1L2(gene name)|psi-mi:AFAP1L2(display_short)|uniprotkb:KIAA1914(gene name synonym)|uniprotkb:XB130(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001001936.1|refseq:NP_001274753.1|refseq:NP_115939.1|ensembl:ENSG00000169129(gene)|ensembl:ENST00000304129(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030113|interpro:IPR030115|rcsb pdb:2COF|genbank_protein_gi:119569855(identity)|refseq:EAW49470(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:xtf4ZVC+dUH9bcyRp+28iTGOG/89606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8IZY2 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2838910|uniprotkb:Q96S58|uniprotkb:Q9UKP8|uniprotkb:Q9BZC4|uniprotkb:Q9NR73|ensembl:ENSP00000263094 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:abca7_human(display_long)|uniprotkb:ABCA7(gene name)|psi-mi:ABCA7(display_short)|uniprotkb:ATP-binding cassette sub-family A member 7(gene name synonym)|uniprotkb:ABCA-SSN(gene name synonym)|uniprotkb:Autoantigen SS-N(gene name synonym)|uniprotkb:Macrophage ABC transporter(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:XP_011525930.1|refseq:NP_061985.2|go:"GO:0007613"(memory)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030054"(cell junction)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033344"(cholesterol efflux)|ensembl:ENSG00000064687(gene)|ensembl:ENST00000263094(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001891"(phagocytic cup)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034188"(apolipoprotein A-I receptor activity)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0038027"(apolipoprotein A-I-mediated signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006909"(phagocytosis)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|interpro:IPR017871|interpro:IPR026082|interpro:IPR027417|interpro:IPR030369|mint:Q8IZY2|reactome:R-HSA-1369062|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044857"(plasma membrane raft organization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090554"(phosphatidylcholine floppase activity)|go:"GO:0090556"(phosphatidylserine floppase activity)|go:"GO:0097386"(glial cell projection)|go:"GO:0140328"(floppase activity)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|genbank_protein_gi:119589967(identity)|refseq:EAW69561(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 8 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:DiwObTKmvpE+8PaBiedWGwuNY9w9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8IZ26 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-10264496|uniprotkb:Q9BSZ0|uniprotkb:D3DWN1|ensembl:ENSP00000341528 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:znf34_human(display_long)|uniprotkb:ZNF34(gene name)|psi-mi:ZNF34(display_short)|uniprotkb:KOX32(gene name synonym)|uniprotkb:Zinc finger protein KOX32(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001273698.1|refseq:NP_085057.3|refseq:XP_011515616.1|refseq:XP_011515617.1|refseq:XP_011515620.1|ensembl:ENSG00000196378(gene)|ensembl:ENST00000343459(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:XP_016869361.1|refseq:XP_016869362.1|refseq:XP_016869363.1|refseq:XP_011515618.1|refseq:XP_016869364.1|genbank_protein_gi:119602463(identity)|refseq:EAW82057(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 10 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:HUCkuG192ZTy8EWyvyk829L48Uo9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q8IYI6 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|genbank_protein_gi:56417815(identity)|refseq:CAI23095(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 3 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q86YB2 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14405236 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q86yb2_human(display_long)|uniprotkb:DHX8(gene name)|psi-mi:DHX8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR044762|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR003029(S1, RNA binding)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR022967|interpro:IPR027417|refseq:NP_004932.1|genbank_protein_gi:119572064(identity)|refseq:EAW51679(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 1 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:lInHSZ2i4eCy7dtiLepBUodOacI9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q86UX7 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-373158|uniprotkb:Q8IUA1|uniprotkb:Q8N207|uniprotkb:Q9BT48|ensembl:ENSP00000279227 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:urp2_human(display_long)|uniprotkb:FERMT3(gene name)|psi-mi:FERMT3(display_short)|uniprotkb:KIND3(gene name synonym)|uniprotkb:MIG2B(gene name synonym)|uniprotkb:URP2(gene name synonym)|uniprotkb:Unc-112-related protein 2(gene name synonym)|uniprotkb:Kindlin-3(gene name synonym)|uniprotkb:MIG2-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_113659.3|refseq:NP_848537.1|refseq:XP_011543596.1|ensembl:ENSG00000149781(gene)|ensembl:ENST00000279227(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0033632"(regulation of cell-cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042995"(cell projection)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019748|interpro:IPR019749|interpro:IPR035963|interpro:IPR037837|interpro:IPR037843|interpro:IPR040790|rcsb pdb:2YS3|rcsb pdb:6V97|rcsb pdb:6V9G|rcsb pdb:7C3M|reactome:R-HSA-114608|refseq:XP_016873887.1|genbank_protein_gi:28626504(identity)|refseq:NP_113659(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:BDLaeBD6Ycz4HAh/4QlZeSZurxY9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q7Z419 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2129982|uniprotkb:B3KUA8|uniprotkb:Q5TB85|uniprotkb:Q6P4Q0|uniprotkb:Q8N3R7|uniprotkb:Q9BX38|uniprotkb:B4DZI2|ensembl:ENSP00000259939 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:r144b_human(display_long)|uniprotkb:RNF144B(gene name)|psi-mi:RNF144B(display_short)|uniprotkb:IBRDC2(gene name synonym)|uniprotkb:P53RFP(gene name synonym)|uniprotkb:RING finger protein 144B(gene name synonym)|uniprotkb:IBR domain-containing protein 2(gene name synonym)|uniprotkb:p53-inducible RING finger protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_877434.2|dip:DIP-43771N|ensembl:ENSG00000137393(gene)|ensembl:ENST00000259939(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|genbank_protein_gi:50284696(identity)|refseq:NP_877434(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 18 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:Ep53jYpmEeClpBZYNkPKrQgy/0A9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q70EK9 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14405234|ensembl:ENSP00000423333|uniprotkb:Q8IWJ8 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ubp51_human(display_long)|uniprotkb:USP51(gene name)|psi-mi:USP51(display_short)|uniprotkb:Deubiquitinating enzyme 51(gene name synonym)|uniprotkb:Ubiquitin thioesterase 51(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 51(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) interpro:IPR038765|mint:Q70EK9|ensembl:ENSG00000247746(gene)|ensembl:ENST00000500968(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0042393"(histone binding)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|interpro:IPR028889|interpro:IPR033383|refseq:NP_958443.1|refseq:XP_016884788.1|refseq:XP_016884789.1|refseq:XP_016884790.1|genbank_protein_gi:27370664(identity)|refseq:AAH35907(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 8 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:W9XXkq7CKWSVoSztbvO+0UVSKt89606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 intact:EBI-14405232 intact:EBI-8430745|intact:MINT-8081619 - psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ca229_human(display_short)|psi-mi:EBI-14405232(display_long)|uniprotkb:C1orf229(gene name)|psi-mi:C1orf229(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) uniprotkb:Q6ZS94(uniprot-removed-ac)|genbank_protein_gi:46409434(identity)|refseq:NP_997284(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|comment:This prey was identified in band no. 20 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:h2Ey7foHvwuoFPC2anXccDGzCO89606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q6ZP65 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-6872450|ensembl:ENSP00000380690|uniprotkb:A8MUC8|uniprotkb:O95000|uniprotkb:B4DWL0|uniprotkb:B5MDJ0 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:bicl1_human(display_long)|uniprotkb:BICDL1(gene name)|psi-mi:BICDL1(display_short)|uniprotkb:BICDR1(gene name synonym)|uniprotkb:Bicaudal D-related protein 1(gene name synonym)|uniprotkb:CCDC64(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 64A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000135127(gene)|ensembl:ENST00000397558(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034452"(dynactin binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0055107"(Golgi to secretory granule transport)|refseq:NP_997194.2|genbank_protein_gi:119618565(identity)|refseq:EAW98159(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 7 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:Eo9by8BxQI9ChI2zSo/mZ/G1Q409606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q6ZN84 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404745|ensembl:ENSP00000415528|uniprotkb:A0AVL7|uniprotkb:Q53FW3|uniprotkb:Q9H5E5 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ccd81_human(display_long)|uniprotkb:CCDC81(gene name)|psi-mi:CCDC81(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENST00000445632(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|interpro:IPR026295|interpro:IPR028034|interpro:IPR040673|ensembl:ENSG00000149201(gene)|refseq:NP_001149946.1|refseq:NP_068599.3|genbank_protein_gi:226493512(identity)|refseq:NP_001149946(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 5 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:JoFC8dj1sUb3PCxIb9iryJmiQRU9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q6ZMI0 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-5235703|uniprotkb:B7ZKY5|uniprotkb:Q2TA78|uniprotkb:Q6ZMI6|uniprotkb:Q8IW83|uniprotkb:Q8J029|uniprotkb:Q96ES8|uniprotkb:B7ZKY7|uniprotkb:E1B6W7|ensembl:ENSP00000294952 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ppr21_human(display_long)|uniprotkb:PPP1R21(gene name)|psi-mi:PPP1R21(display_short)|uniprotkb:CCDC128(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 128(gene name synonym)|uniprotkb:KLRAQ motif-containing protein 1(gene name synonym)|uniprotkb:KLRAQ1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001129101.1|refseq:NP_001180404.1|refseq:NP_694539.1|ensembl:ENSG00000162869(gene)|ensembl:ENST00000294952(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0016020"(membrane)|interpro:IPR019343|interpro:IPR019348|interpro:IPR040024|genbank_protein_gi:301500682(identity)|refseq:NP_001180404(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 8 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:cp4v9NF+YVUYq0eABVb/gj0TeJA9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q6IPN6 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14405230 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q6ipn6_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|genbank_protein_gi:48734966(identity)|refseq:AAH71841(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 13 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:R/MKSOHZn/10zG1rtV9QlVVrBsc9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q6DKK2 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-948354|ensembl:ENSP00000261647|uniprotkb:Q7L3U8|uniprotkb:Q9NXB2|uniprotkb:A8MZ52|uniprotkb:B3KP62|uniprotkb:B4DN65|uniprotkb:Q9H6G3|uniprotkb:Q2M248 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ttc19_human(display_long)|uniprotkb:TTC19(gene name)|psi-mi:TTC19(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000011295(gene)|ensembl:ENST00000261647(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005813"(centrosome)|go:"GO:0030496"(midbody)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0070469"(respirasome)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR040395|mint:Q6DKK2|refseq:NP_001258349.1|refseq:NP_060245.3|genbank_protein_gi:22547159(identity)|refseq:NP_060245(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 16 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:skTQJ+iUoHBb06IqVhoprLMYEtA9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q5VTE0 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-877809 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417|genbank_protein_gi:74746925(identity)|refseq:Q5VTE0(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 13 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q58F21 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2654243|uniprotkb:Q7Z4A6|uniprotkb:Q6P5T1|uniprotkb:O14789|uniprotkb:Q8IWI6|ensembl:ENSP00000354568|ensembl:ENSP00000384051|ensembl:ENSP00000387822|uniprotkb:A6NF68|uniprotkb:B7Z811|uniprotkb:B7Z890|uniprotkb:B7ZAX7|uniprotkb:D3DT32|uniprotkb:Q05DQ4 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:brdt_human(display_long)|uniprotkb:Cancer/testis antigen 9(gene name synonym)|uniprotkb:RING3-like protein(gene name synonym)|uniprotkb:BRDT(gene name)|psi-mi:BRDT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:XP_011540334.1|refseq:XP_011540335.1|refseq:XP_011540336.1|refseq:XP_011540337.1|refseq:XP_011540338.1|refseq:NP_001229735.2|refseq:NP_001229736.2|refseq:NP_001229737.2|refseq:NP_001229739.2|refseq:NP_001229734.2|refseq:NP_001717.3|refseq:NP_997072.2|ensembl:ENSG00000137948(gene)|ensembl:ENST00000362005(transcript)|ensembl:ENST00000399546(transcript)|ensembl:ENST00000402388(transcript)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0051039"(positive regulation of transcription involved in meiotic cell cycle)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR031354|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|rcsb pdb:2RFJ|rcsb pdb:4FLP|rcsb pdb:4KCX|rcsb pdb:5VBQ|rcsb pdb:5VBR|rcsb pdb:7L73|rcsb pdb:7L99|rcsb pdb:7L9A|refseq:XP_006710916.1|refseq:XP_006710917.1|refseq:XP_006710918.1|refseq:XP_006710919.1|refseq:XP_006710920.1|genbank_protein_gi:28839607(identity)|refseq:AAH47900(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:erpgTXKmhS3kowFf8dHpN8s0mWw9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q49A88 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-751035|intact:EBI-2622203|intact:EBI-2858142|uniprotkb:B7Z2T2|uniprotkb:B8ZZ58|intact:EBI-946963|intact:EBI-1104778|uniprotkb:Q7Z3N3|uniprotkb:Q86T30|uniprotkb:Q8WUJ8|uniprotkb:Q96K47|uniprotkb:Q9H9A3|uniprotkb:Q9UFH0|uniprotkb:Q8IWF8|uniprotkb:B8ZZ41|uniprotkb:D3DN98|uniprotkb:B7Z2Q3 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ccd14_human(display_long)|uniprotkb:CCDC14(gene name)|psi-mi:CCDC14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_073594.4|refseq:NP_001295246.1|refseq:XP_005247767.1|refseq:XP_005247768.1|refseq:XP_005247770.1|refseq:XP_005247771.1|refseq:XP_016862545.1|refseq:XP_016862547.1|refseq:XP_016862548.1|mint:Q49A88|dip:DIP-47727N|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0021762"(substantia nigra development)|go:"GO:0034451"(centriolar satellite)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR029343|genbank_protein_gi:71296882(identity)|refseq:AAH42613(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 3 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:y1bU4io/NA6LIX+pwRkB8gstVuY9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q3LIF1 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14405228 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q3lif1_human(display_long)|uniprotkb:Nbla10545(gene name)|psi-mi:Nbla10545(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) genbank_protein_gi:76879695(identity)|refseq:BAE45717(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 19 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:XLZnhq22PVxMJkmrV/Dix4Tww1Y9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q3LFD5 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2511843|uniprotkb:A8MXD0|uniprotkb:Q70BM7 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ubp41_human(display_long)|uniprotkb:USP41(gene name)|psi-mi:USP41(display_short)|uniprotkb:Ubiquitin-specific-processing protease 41(gene name synonym)|uniprotkb:Deubiquitinating enzyme 41(gene name synonym)|uniprotkb:Ubiquitin thioesterase 41(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR028889|interpro:IPR018200|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|reactome:R-HSA-1169408|interpro:IPR038765|genbank_protein_gi:40788037(identity)|refseq:CAE52971(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 5 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:t6Qvd6O/rZGKIe/BhBNHwoCl3WI9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q1RLM6 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404735 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q1rlm6_human(display_long)|uniprotkb:FBXL10(gene name)|psi-mi:FBXL10(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0003677"(DNA binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR041070|interpro:IPR041667|genbank_protein_gi:92098161(identity)|refseq:AAI15381(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 3 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:fnuXI7uyguLEhR8/rSXGMnN4ALE9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q14BN4 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1|genbank_protein_gi:10047277(identity)|refseq:BAB13427(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q14964 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-3048577|ensembl:ENSP00000322594|uniprotkb:A8KAA4|uniprotkb:Q8N6W2 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:rb39a_human(display_long)|uniprotkb:RAB39A(gene name)|psi-mi:RAB39A(display_short)|uniprotkb:RAB39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000179331(gene)|ensembl:ENST00000320578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041818|reactome:R-HSA-6811438|reactome:R-HSA-8873719|reactome:R-HSA-8876198|refseq:NP_059986.1|dip:DIP-60521N|genbank_protein_gi:39930371(identity)|refseq:NP_059986(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:jpkNU7VaaBLmc8P2kLuNq++1T2I9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q13795 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-4402792|uniprotkb:E1P5J9|uniprotkb:Q6IBQ0|uniprotkb:A0A087WY13|uniprotkb:V9GYH4|uniprotkb:B7ZKX7|ensembl:ENSP00000479616|ensembl:ENSP00000479940|ensembl:ENSP00000483486 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:arfrp_human(display_long)|uniprotkb:ARFRP1(gene name)|psi-mi:ARFRP1(display_short)|uniprotkb:ARP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001128230.1|refseq:NP_003215.1|refseq:XP_011526784.1|refseq:XP_011526785.1|refseq:NP_001254474.1|refseq:NP_001254475.1|refseq:NP_001254476.1|refseq:NP_001254477.1|refseq:NP_001254478.1|refseq:XP_016883065.1|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|reactome:R-HSA-6811440|go:"GO:0033365"(protein localization to organelle)|ensembl:ENSG00000101246(gene)|ensembl:ENST00000618838(transcript)|ensembl:ENST00000619493(transcript)|ensembl:ENST00000622789(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007165"(signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0016020"(membrane)|go:"GO:0032588"(trans-Golgi network membrane)|genbank_protein_gi:4507449(identity)|refseq:NP_003215(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:Sh4Hh6c3BYS03iQYq6HTgt0rhso9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q13439 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1037845|uniprotkb:Q13270|uniprotkb:Q13654|uniprotkb:Q14436|uniprotkb:F8W8Q7|uniprotkb:Q59EW8|ensembl:ENSP00000354486 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:goga4_human(display_long)|uniprotkb:GOLGA4(gene name)|psi-mi:GOLGA4(display_short)|uniprotkb:Trans-Golgi p230(gene name synonym)|uniprotkb:256 kDa golgin(gene name synonym)|uniprotkb:Golgin-245(gene name synonym)|uniprotkb:Protein 72.1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001166184.1|refseq:NP_002069.2|ensembl:ENSG00000144674(gene)|ensembl:ENST00000361924(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000237(GRIP)|rcsb pdb:1R4A|rcsb pdb:1UPT|reactome:R-HSA-6811440|reactome:R-HSA-9673768|genbank_protein_gi:62088966(identity)|refseq:BAD92930(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:iRvTCfQleDllP1zq0dlAVyX58JU9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q12931 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1055869|uniprotkb:O43642|uniprotkb:O75235|uniprotkb:Q9UHL5|uniprotkb:B4DR68|uniprotkb:F5H897|uniprotkb:D3DUC8|ensembl:ENSP00000246957 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:trap1_human(display_long)|uniprotkb:TRAP1(gene name)|psi-mi:TRAP1(display_short)|uniprotkb:HSP75(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein(gene name synonym)|uniprotkb:TNFR-associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_057376.2|refseq:NP_001258978.1|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0009386"(translational attenuation)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903751"(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:Q12931|rcsb pdb:4Z1F|rcsb pdb:4Z1G|rcsb pdb:4Z1H|rcsb pdb:4Z1I|rcsb pdb:5F3K|rcsb pdb:5F5R|rcsb pdb:5HPH|rcsb pdb:5Y3N|rcsb pdb:5Y3O|rcsb pdb:6XG6|rcsb pdb:7C04|rcsb pdb:7C05|rcsb pdb:7C7B|rcsb pdb:7C7C|reactome:R-HSA-611105|ensembl:ENSG00000126602(gene)|ensembl:ENST00000246957(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|dip:DIP-6250N|genbank_protein_gi:1082886(identity)|refseq:A55877(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 9 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:O/i+7vgZQcDQF3xJTeqNLbWiQ8U9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q07866 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-721019|uniprotkb:F8VTM4|uniprotkb:Q7RTQ3|uniprotkb:Q86V77|uniprotkb:Q86V78|uniprotkb:Q86V79|uniprotkb:Q7RTM2|uniprotkb:Q7RTM3|uniprotkb:Q7RTM5|uniprotkb:Q7RTP9|uniprotkb:Q7RTQ5|uniprotkb:Q7RTQ6|uniprotkb:Q86SF5|uniprotkb:Q86TF5|uniprotkb:Q86V74|uniprotkb:Q86V75|uniprotkb:Q86V76|uniprotkb:Q96H62|uniprotkb:A6NF62|intact:EBI-28976313|ensembl:ENSP00000341154 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:klc1_human(display_long)|uniprotkb:KLC1(gene name)|psi-mi:KLC1(display_short)|uniprotkb:KLC(gene name synonym)|uniprotkb:KNS2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001123579.1|refseq:NP_005543.2|refseq:NP_891553.2|ensembl:ENST00000452929|ensembl:ENSP00000414982|ensembl:ENST00000553286|ensembl:ENSP00000452487|ensembl:ENST00000246489|ensembl:ENSP00000246489|ensembl:ENST00000334553|ensembl:ENST00000554228|ensembl:ENSP00000450616|ensembl:ENST00000557450|ensembl:ENSP00000450648|ensembl:ENST00000634686|ensembl:ENSP00000488938|ensembl:ENSP00000334523|ensembl:ENST00000347839|ensembl:ENSP00000334618|ensembl:ENSP00000341154|ensembl:ENST00000389744|ensembl:ENSP00000374394|dip:DIP-40371N|ensembl:ENSG00000126214(gene)|ensembl:ENST00000348520(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035617"(stress granule disassembly)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|mint:Q07866|rcsb pdb:3NF1|rcsb pdb:5OJ8|reactome:R-HSA-2132295|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0030426"(growth cone)|genbank_protein_gi:33186844(identity)|refseq:AA01295(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 6 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:T7SJbB/PScRqj74O/NH4q1KU0YM9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:Q00013 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-711788|uniprotkb:B4DZV5|uniprotkb:Q5J7V5|uniprotkb:G3XAI1|uniprotkb:Q2TSB6|ensembl:ENSP00000358547 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:em55_human(display_long)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)|uniprotkb:MPP1(gene name)|psi-mi:MPP1(display_short)|uniprotkb:EMP55(gene name synonym)|uniprotkb:DXS552E(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001159932.1|refseq:NP_001159933.1|refseq:NP_001159934.1|refseq:NP_002427.1|ensembl:ENSG00000130830(gene)|ensembl:ENST00000369534(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:Q00013|rcsb pdb:2EJY|rcsb pdb:2EV8|rcsb pdb:3NEY|reactome:R-HSA-9662361|genbank_protein_gi:262118263(identity)|refseq:NP_001159934(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 13 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:b9QmIlmQ5SZHnOQfGSezmcvaDls9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P78368 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-748380|uniprotkb:O00704|uniprotkb:Q8WUB1|uniprotkb:B5BU42|ensembl:ENSP00000255641 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:kc1g2_human(display_long)|uniprotkb:CK1G2(gene name synonym)|uniprotkb:CSNK1G2(gene name)|psi-mi:CSNK1G2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001310.3|ensembl:ENSG00000133275(gene)|ensembl:ENST00000255641(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022247|rcsb pdb:2C47|reactome:R-HSA-1660661|reactome:R-HSA-4641262|genbank_protein_gi:119589837(identity)|refseq:EAW69431(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:h+GOdcwwLTmwj0dQKT1JQGwoaC09606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P68371 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|genbank_protein_gi:5174735(identity)|refseq:NP_006079(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 13 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P43686 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|genbank_protein_gi:5729991(identity)|refseq:NP_006494(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 14 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P35998 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-359710|uniprotkb:B7Z5E2|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644|ensembl:ENSP00000391211|ensembl:ENSP00000502939|ensembl:ENSP00000503179|ensembl:ENSP00000504608 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001191382.1|refseq:NP_002794.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|interpro:IPR003960(AAA ATPase, conserved site)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|ensembl:ENSG00000161057(gene)|ensembl:ENST00000292644(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|ensembl:ENST00000435765(transcript)|ensembl:ENST00000678493(transcript)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|ensembl:ENST00000679205(transcript)|ensembl:ENST00000679341(transcript)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5VHQ|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610780|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|dip:DIP-27554N|genbank_protein_gi:4506209(identity)|refseq:NP_002794(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 13 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P30291 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-914695|uniprotkb:D3DQV0|uniprotkb:B3KVE1|intact:EBI-28966863|ensembl:ENSP00000402084 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:wee1_human(display_long)|uniprotkb:WEE1(gene name)|psi-mi:WEE1(display_short)|uniprotkb:Wee1A kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENST00000299613|ensembl:ENSP00000299613|ensembl:ENSP00000402084|ensembl:ENST00000681684|ensembl:ENSP00000506667|refseq:NP_003381.1|refseq:NP_001137448.1|dip:DIP-37969N|ensembl:ENSG00000166483(gene)|ensembl:ENST00000450114(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051301"(cell division)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017164(Wee1-like protein kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P30291|rcsb pdb:1X8B|rcsb pdb:2IN6|rcsb pdb:2IO6|rcsb pdb:2Z2W|rcsb pdb:3BI6|rcsb pdb:3BIZ|rcsb pdb:3CQE|rcsb pdb:3CR0|rcsb pdb:5V5Y|rcsb pdb:5VC3|rcsb pdb:5VC4|rcsb pdb:5VC5|rcsb pdb:5VC6|rcsb pdb:5VD2|rcsb pdb:5VD4|rcsb pdb:5VD5|rcsb pdb:5VD7|rcsb pdb:5VD8|rcsb pdb:5VD9|rcsb pdb:5VDA|reactome:R-HSA-156711|reactome:R-HSA-69202|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-69656|reactome:R-HSA-75035|reactome:R-HSA-983231|genbank_protein_gi:221307502(identity)|refseq:NP_001137448(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:dwPDwRI0VD+VD5FVccuU20y/WAE9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P23396 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N|genbank_protein_gi:15718687(identity)|refseq:NP_000996(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 21 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P22492 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492|genbank_protein_gi:183751(identity)|refseq:AAA35944(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 19 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P68363 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328|genbank_protein_gi:340021(identity)|refseq:AAA91576(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 13 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P67809 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|genbank_protein_gi:340419(identity)|refseq:AAA61308(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 17 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P19338 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226|genbank_protein_gi:189306(identity)|refseq:AAA59954(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P14136 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|genbank_protein_gi:16265836(identity)|refseq:AAL16662(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P62191 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|ensembl:ENSP00000261303|uniprotkb:Q6NW36|uniprotkb:B4DR63 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_002793.2|ensembl:ENST00000261303(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|ensembl:ENSG00000100764(gene)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFQ|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-8852276|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_001317141.1|refseq:XP_016876959.1|genbank_protein_gi:6679501(identity)|refseq:NP_002793(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P54136 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-355482|uniprotkb:Q9BWA1|uniprotkb:B2RBS9|uniprotkb:Q53GY4|intact:EBI-28985219|ensembl:ENSP00000231572 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:syrc_human(display_long)|uniprotkb:RARS1(gene name)|psi-mi:RARS1(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:RARS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_002878.2|ensembl:ENSG00000113643(gene)|ensembl:ENST00000231572(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0034618"(arginine binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR035684|interpro:IPR036695|mint:P54136|rcsb pdb:4Q2T|rcsb pdb:4Q2X|rcsb pdb:4Q2Y|rcsb pdb:4R3Z|rcsb pdb:4ZAJ|reactome:R-HSA-2408522|reactome:R-HSA-379716|ensembl:ENSP00000231572|genbank_protein_gi:1217668(identity)|refseq:AAB35627(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 6 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:oM9gWF1NucjgVjBFm4DcjmnQNCE9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P13639 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-352560|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001952.1|ensembl:ENSG00000167658(gene)|ensembl:ENST00000309311(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725|genbank_protein_gi:19353009(identity)|refseq:AAH24689(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P11142 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N|genbank_protein_gi:5729877(identity)|refseq:NP_006588(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 9 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P52732 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-355697|uniprotkb:A0AV49|uniprotkb:Q15716|uniprotkb:Q5VWX0|uniprotkb:B2RMV3|ensembl:ENSP00000260731 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:kif11_human(display_long)|uniprotkb:KIF11(gene name)|psi-mi:KIF11(display_short)|uniprotkb:EG5(gene name synonym)|uniprotkb:KNSL1(gene name synonym)|uniprotkb:TRIP5(gene name synonym)|uniprotkb:Kinesin-related motor protein Eg5(gene name synonym)|uniprotkb:Kinesin-like spindle protein HKSP(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 5(gene name synonym)|uniprotkb:Kinesin-like protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_004514.2|ensembl:ENSG00000138160(gene)|ensembl:ENST00000260731(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|rcsb pdb:1X88|rcsb pdb:1YRS|rcsb pdb:2FKY|rcsb pdb:2FL2|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR025901|interpro:IPR027417|interpro:IPR036961|rcsb pdb:1II6|rcsb pdb:1Q0B|rcsb pdb:2FL6|rcsb pdb:2FME|rcsb pdb:2G1Q|rcsb pdb:2GM1|rcsb pdb:2IEH|rcsb pdb:2PG2|rcsb pdb:2Q2Y|rcsb pdb:2Q2Z|rcsb pdb:2UYI|rcsb pdb:2UYM|rcsb pdb:2WOG|rcsb pdb:2X2R|rcsb pdb:2X7C|rcsb pdb:2X7D|rcsb pdb:2X7E|rcsb pdb:2XAE|rcsb pdb:3CJO|rcsb pdb:3HQD|rcsb pdb:3K3B|rcsb pdb:3K5E|rcsb pdb:3KEN|rcsb pdb:3L9H|rcsb pdb:3WPN|rcsb pdb:3ZCW|rcsb pdb:4A1Z|rcsb pdb:4A28|rcsb pdb:4A50|rcsb pdb:4A51|rcsb pdb:4A5Y|rcsb pdb:4AP0|rcsb pdb:4AQV|rcsb pdb:4AQW|rcsb pdb:4AS7|rcsb pdb:4B7B|rcsb pdb:4BBG|rcsb pdb:4BXN|rcsb pdb:4CK5|rcsb pdb:4CK6|rcsb pdb:4CK7|rcsb pdb:4ZCA|rcsb pdb:4ZHI|rcsb pdb:5JV3|rcsb pdb:5ZO7|rcsb pdb:5ZO8|rcsb pdb:5ZO9|rcsb pdb:6G6Y|rcsb pdb:6G6Z|rcsb pdb:6HKX|rcsb pdb:6HKY|rcsb pdb:6TA3|rcsb pdb:6TA4|rcsb pdb:6TIW|rcsb pdb:6TLE|rcsb pdb:6TRL|rcsb pdb:6Y1I|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-53686N|genbank_protein_gi:13699824(identity)|refseq:NP_004514(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 1 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:YimbfuWYTSuyqgfs2RF8kCx2+xE9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P51659 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-358398|ensembl:ENSP00000424940|uniprotkb:B4DNV1|uniprotkb:B4DVS5|uniprotkb:E9PB82|uniprotkb:F5HE57 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:dhb4_human(display_long)|uniprotkb:HSD17B4(gene name)|psi-mi:HSD17B4(display_short)|uniprotkb:EDH17B4(gene name synonym)|uniprotkb:D-bifunctional protein(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 4(gene name synonym)|uniprotkb:Multifunctional protein 2(gene name synonym)|uniprotkb:SDR8C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 8C member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_000405.1|refseq:NP_001186220.1|refseq:NP_001186221.1|refseq:NP_001278956.1|refseq:NP_001278957.1|ensembl:ENSG00000133835(gene)|ensembl:ENST00000510025(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0033989"(3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity)|go:"GO:0036111"(very long-chain fatty-acyl-CoA metabolic process)|go:"GO:0036112"(medium-chain fatty-acyl-CoA metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0060009"(Sertoli cell development)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR002539(MaoC-like dehydratase)|interpro:IPR003033(Sterol-binding)|interpro:IPR020904|interpro:IPR029069|interpro:IPR036291|interpro:IPR036527|rcsb pdb:1IKT|rcsb pdb:1S9C|rcsb pdb:1ZBQ|rcsb pdb:6Z1W|rcsb pdb:6Z1X|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-390247|reactome:R-HSA-9033241|reactome:R-HSA-9033500|genbank_protein_gi:313482810(identity)|refseq:NP_001186220(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:i3A0dh9gAO2vfrCYXvo2U6+PwJQ9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P0DMV8 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-11052499|uniprotkb:Q9UQM0|uniprotkb:Q5SP17|uniprotkb:Q5JQI4|uniprotkb:P08107|uniprotkb:B4E3B6|uniprotkb:Q9UQL9|uniprotkb:P19790|ensembl:ENSP00000364802|ensembl:ENSP00000382915|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:hs71a_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSX70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 1(gene name synonym)|uniprotkb:HSP72(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_005336.3|refseq:NP_005337.2|ensembl:ENSG00000204389(gene)|ensembl:ENSG00000215328(gene)|ensembl:ENSG00000234475(gene)|ensembl:ENSG00000235941(gene)|ensembl:ENSG00000237724(gene)|ensembl:ENST00000375651(transcript)|ensembl:ENST00000400040(transcript)|ensembl:ENST00000430065(transcript)|ensembl:ENST00000433487(transcript)|ensembl:ENST00000441618(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007041"(lysosomal transport)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031249"(denatured protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070370"(cellular heat acclimation)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0072562"(blood microparticle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902380"(positive regulation of endoribonuclease activity)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P0DMV8|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:2LMG|rcsb pdb:3A8Y|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|rcsb pdb:3Q49|rcsb pdb:4IO8|rcsb pdb:4J8F|rcsb pdb:4PO2|rcsb pdb:4WV5|rcsb pdb:4WV7|rcsb pdb:5AQW|rcsb pdb:5AQX|rcsb pdb:5AQY|rcsb pdb:5AQZ|rcsb pdb:5AR0|rcsb pdb:5BN8|rcsb pdb:5BN9|rcsb pdb:5BPL|rcsb pdb:5BPM|rcsb pdb:5BPN|rcsb pdb:5GJJ|rcsb pdb:5MKR|rcsb pdb:5MKS|rcsb pdb:5XI9|rcsb pdb:5XIR|rcsb pdb:6FHK|rcsb pdb:6G3R|rcsb pdb:6G3S|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-168330|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-450408|reactome:R-HSA-6798695|genbank_protein_gi:167466173(identity)|refseq:NP_005337(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 10 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:NFv4uj12xAWIr+OltarRlLDPr949606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P08238 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N|genbank_protein_gi:39644662(identity)|refseq:AAH09206(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 3 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P49761 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-745579|uniprotkb:Q53Y48|uniprotkb:Q9BRS3|uniprotkb:Q9BUJ7|uniprotkb:D3DW59 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:clk3_human(display_long)|uniprotkb:CDC-like kinase 3(gene name synonym)|uniprotkb:CLK3(gene name)|psi-mi:CLK3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:NP_001123500.1|refseq:NP_003983.2|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|rcsb pdb:2EU9|rcsb pdb:2EXE|rcsb pdb:2WU6|rcsb pdb:2WU7|rcsb pdb:3RAW|rcsb pdb:6FT7|rcsb pdb:6FYP|rcsb pdb:6FYR|rcsb pdb:6KHF|rcsb pdb:6RCT|rcsb pdb:6YTW|rcsb pdb:6YTY|rcsb pdb:6YU1|rcsb pdb:6Z2V|rcsb pdb:6Z51|rcsb pdb:6Z52|rcsb pdb:6Z53|rcsb pdb:6Z54|rcsb pdb:6Z55|refseq:XP_016877398.1|refseq:XP_016877399.1|mint:P49761|genbank_protein_gi:13543919(identity)|refseq:AAH06103(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 2 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:OKVI1liX72xOFK78aTuholNAfio9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P49411 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1|genbank_protein_gi:704416(identity)|refseq:AAB00499(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 13 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P06748 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|genbank_protein_gi:119581852(identity)|refseq:EAW61448(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 18 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P02679 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1034422|uniprotkb:P04469|uniprotkb:P04470|uniprotkb:Q96A14|uniprotkb:Q96KJ3|uniprotkb:A8K057|uniprotkb:Q53Y18|uniprotkb:Q9UC62|uniprotkb:Q9UC63|uniprotkb:Q9UCF3|ensembl:ENSP00000336829 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:fibg_human(display_long)|uniprotkb:FGG(gene name)|psi-mi:FGG(display_short)|uniprotkb:PRO2061(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_000500.2|refseq:NP_068656.2|ensembl:ENSG00000171557(gene)|ensembl:ENST00000336098(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0009306"(protein secretion)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0036345"(platelet maturation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR037581|mint:P02679|rcsb pdb:1DUG|rcsb pdb:1FIB|rcsb pdb:1FIC|rcsb pdb:1FID|rcsb pdb:1FZA|go:"GO:0070527"(platelet aggregation)|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2FIB|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2HWL|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2VDO|rcsb pdb:2VDP|rcsb pdb:2VDQ|rcsb pdb:2VDR|rcsb pdb:2VR3|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Y7L|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:2Q9I|rcsb pdb:3FIB|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:4B60|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29644N|genbank_protein_gi:223170(identity)|refseq:0602239A(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:QKWesyU4/fduceFtu5zq31oGhYI9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P00742 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-719750|uniprotkb:Q14340|ensembl:ENSP00000364709 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:fa10_human(display_long)|uniprotkb:Stuart factor(gene name synonym)|uniprotkb:Stuart-Prower factor(gene name synonym)|uniprotkb:F10(gene name)|psi-mi:F10(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_000495.1|ensembl:ENSG00000126218(gene)|ensembl:ENST00000375559(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007596"(blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR018097|interpro:IPR018114|interpro:IPR033116|interpro:IPR035972|interpro:IPR043504|mint:P00742|rcsb pdb:1C5M|rcsb pdb:1EZQ|rcsb pdb:1F0R|rcsb pdb:1F0S|rcsb pdb:1FAX|rcsb pdb:1FJS|rcsb pdb:1FXY|rcsb pdb:1G2L|rcsb pdb:1G2M|rcsb pdb:1HCG|rcsb pdb:1IOE|rcsb pdb:1IQE|rcsb pdb:1IQF|rcsb pdb:1IQG|rcsb pdb:1IQH|rcsb pdb:1IQI|rcsb pdb:1IQJ|rcsb pdb:1IQK|rcsb pdb:1IQL|rcsb pdb:1IQM|rcsb pdb:1IQN|rcsb pdb:1KSN|rcsb pdb:1LPG|rcsb pdb:1LPK|rcsb pdb:1LPZ|rcsb pdb:1LQD|rcsb pdb:1MQ5|rcsb pdb:1MQ6|rcsb pdb:1MSX|rcsb pdb:1NFU|rcsb pdb:1NFW|rcsb pdb:1NFX|rcsb pdb:1NFY|rcsb pdb:1NL8|rcsb pdb:1P0S|rcsb pdb:1V3X|rcsb pdb:1WU1|rcsb pdb:1XKA|rcsb pdb:1XKB|rcsb pdb:1Z6E|rcsb pdb:2BMG|rcsb pdb:2BOH|rcsb pdb:2BOK|rcsb pdb:2BQ6|rcsb pdb:2BQ7|rcsb pdb:2BQW|rcsb pdb:2CJI|rcsb pdb:2D1J|rcsb pdb:2EI6|rcsb pdb:2EI7|rcsb pdb:2EI8|rcsb pdb:2FZZ|rcsb pdb:2G00|rcsb pdb:2GD4|rcsb pdb:2H9E|rcsb pdb:2J2U|rcsb pdb:2J34|rcsb pdb:2J38|rcsb pdb:2J4I|rcsb pdb:2J94|rcsb pdb:2J95|rcsb pdb:2P16|rcsb pdb:2P3F|rcsb pdb:2P3T|rcsb pdb:2P3U|rcsb pdb:2P93|rcsb pdb:2P94|rcsb pdb:2P95|rcsb pdb:2PHB|rcsb pdb:2PR3|rcsb pdb:2Q1J|rcsb pdb:2RA0|rcsb pdb:2UWL|rcsb pdb:2UWO|rcsb pdb:2UWP|rcsb pdb:2VH0|rcsb pdb:2VH6|rcsb pdb:2VVC|rcsb pdb:2VVU|rcsb pdb:2VVV|rcsb pdb:2VWL|rcsb pdb:2VWM|rcsb pdb:2VWN|rcsb pdb:2VWO|rcsb pdb:2W26|rcsb pdb:2W3I|rcsb pdb:2W3K|rcsb pdb:2WYG|rcsb pdb:2WYJ|rcsb pdb:2XBV|rcsb pdb:2XBW|rcsb pdb:2XBX|rcsb pdb:2XBY|rcsb pdb:2XC0|rcsb pdb:2JKH|rcsb pdb:2XC4|rcsb pdb:2XC5|rcsb pdb:2Y5F|rcsb pdb:2Y5G|rcsb pdb:2Y5H|rcsb pdb:2Y7X|rcsb pdb:2Y7Z|rcsb pdb:2Y80|rcsb pdb:2Y81|rcsb pdb:2Y82|rcsb pdb:3CEN|rcsb pdb:3CS7|rcsb pdb:3ENS|rcsb pdb:3FFG|rcsb pdb:3HPT|rcsb pdb:3IIT|rcsb pdb:3K9X|rcsb pdb:3KL6|rcsb pdb:3KQB|rcsb pdb:3KQC|rcsb pdb:3KQD|rcsb pdb:3KQE|rcsb pdb:3LIW|rcsb pdb:3M36|rcsb pdb:3M37|rcsb pdb:3Q3K|rcsb pdb:3SW2|rcsb pdb:3TK6|rcsb pdb:4A7I|rcsb pdb:4BTI|rcsb pdb:4BTT|rcsb pdb:4BTU|rcsb pdb:4Y6D|rcsb pdb:4Y71|rcsb pdb:4Y76|rcsb pdb:4Y79|rcsb pdb:4Y7A|rcsb pdb:4Y7B|rcsb pdb:4ZH8|rcsb pdb:4ZHA|rcsb pdb:5JQY|rcsb pdb:5JTC|rcsb pdb:5JZ8|rcsb pdb:5JZU|rcsb pdb:5K0H|rcsb pdb:5VOE|rcsb pdb:5VOF|rcsb pdb:6Q9F|rcsb pdb:6Q9I|rcsb pdb:6RK9|rcsb pdb:6YYW|rcsb pdb:6YYX|rcsb pdb:6YYY|rcsb pdb:6Z6Q|rcsb pdb:6Z6R|rcsb pdb:7BMI|rcsb pdb:7BMJ|rcsb pdb:7E6J|rcsb pdb:3TK5|reactome:R-HSA-140834|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-9672383|reactome:R-HSA-9672396|reactome:R-HSA-9673202|refseq:NP_001299603.1|refseq:NP_001299604.1|dip:DIP-29896N|genbank_protein_gi:180336(identity)|refseq:AAA51984(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:EiG38fLKwrbGJftF5k4xjLvlYhA9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O75928 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-348555|uniprotkb:O75927|uniprotkb:Q96BT5|uniprotkb:Q96KE3|ensembl:ENSP00000465676 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:pias2_human(display_long)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIASX(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_004662.2|refseq:NP_775298.1|refseq:NP_001310989.1|ensembl:ENSG00000078043(gene)|ensembl:ENST00000585916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027228|interpro:IPR036361|interpro:IPR038654|mint:O75928|rcsb pdb:2ASQ|rcsb pdb:4FO9|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-4090294|genbank_protein_gi:56699458(identity)|refseq:NP_004662(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 9 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:/7gObRzCbafNTNMKe8leGG/h2NQ9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O75688 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1047039|uniprotkb:Q9HAY8|uniprotkb:Q461Q2|uniprotkb:Q658R4|ensembl:ENSP00000282412|uniprotkb:Q96ER6|uniprotkb:Q4J6C1|uniprotkb:Q4J6C2 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ppm1b_human(display_long)|uniprotkb:Protein phosphatase 2C isoform beta(gene name synonym)|uniprotkb:PPM1B(gene name)|psi-mi:PPM1B(display_short)|uniprotkb:PP2CB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001028729.1|refseq:NP_002697.1|refseq:NP_808907.1|refseq:NP_808908.1|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR012911(Protein serine/threonine phosphatase 2C, C-terminal)|interpro:IPR036457|interpro:IPR036580|mint:O75688|rcsb pdb:2P8E|reactome:R-HSA-1169408|ensembl:ENSG00000138032(gene)|ensembl:ENST00000282412(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006499"(N-terminal protein myristoylation)|go:"GO:0016020"(membrane)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|genbank_protein_gi:4505995(identity)|refseq:NP_002697(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:cwwfGSSTv9pR/XNLa9UxQ/6hpD89606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O60825 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-764425|uniprotkb:O60824|uniprotkb:Q5VVQ4|uniprotkb:Q9H3P1|uniprotkb:Q5VVQ3|ensembl:ENSP00000356047 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:f262_human(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase heart-type isozyme(gene name synonym)|uniprotkb:PFKFB2(gene name)|psi-mi:PFKFB2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001018063.1|refseq:NP_006203.2|ensembl:ENSG00000123836(gene)|ensembl:ENST00000367080(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0033133"(positive regulation of glucokinase activity)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|mint:O60825|rcsb pdb:5HTK|reactome:R-HSA-9634600|genbank_protein_gi:64762445(identity)|refseq:NP_001018063(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:VAIXM3xzM91KrxL92RdTLkqVcaM9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O60547 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-746373|uniprotkb:O75357|uniprotkb:Q5T954|uniprotkb:Q6FH09|uniprotkb:Q9UGZ3|uniprotkb:Q9UJK9|ensembl:ENSP00000370194|intact:EBI-10968896|uniprotkb:E9PI88 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:gmds_human(display_long)|uniprotkb:GDP-D-mannose dehydratase(gene name synonym)|uniprotkb:GMDS(gene name)|psi-mi:GMDS(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001491.1|ensembl:ENSG00000112699(gene)|ensembl:ENST00000380815(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008446"(GDP-mannose 4,6-dehydratase activity)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0042351"('de novo' GDP-L-fucose biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070401"(NADP+ binding)|interpro:IPR006368(GDP-mannose 4,6-dehydratase)|interpro:IPR016040("NAD(P)-binding")|interpro:IPR036291|rcsb pdb:1T2A|rcsb pdb:5IN4|rcsb pdb:5IN5|rcsb pdb:6GPJ|rcsb pdb:6GPK|rcsb pdb:6GPL|rcsb pdb:6Q94|reactome:R-HSA-6787639|refseq:NP_001240775.1|genbank_protein_gi:4504031(identity)|refseq:NP_001491(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:phGw3/m75gYQcBlRP3OXK4mQvhM9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O60282 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-717170|uniprotkb:O95079|uniprotkb:Q2YDC5|ensembl:ENSP00000393379|ensembl:ENSP00000503013 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:kif5c_human(display_long)|uniprotkb:Kinesin heavy chain neuron-specific 2(gene name synonym)|uniprotkb:KIF5C(gene name)|psi-mi:KIF5C(display_short)|uniprotkb:KIAA0531(gene name synonym)|uniprotkb:NKHC2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_004513.1|refseq:XP_011509459.1|refseq:XP_016859551.1|ensembl:ENSG00000168280(gene)|ensembl:ENST00000435030(transcript)|ensembl:ENST00000677891(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0006996"(organelle organization)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0150034"(distal axon)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|mint:O60282|reactome:R-HSA-264876|interpro:IPR036961|genbank_protein_gi:33878050(identity)|refseq:AAH17298(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 16 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:4TqyBBhm1/nyaCSyz66oisPiwpA9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O15119 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-3452216|uniprotkb:Q9UKF8|uniprotkb:Q8TB20|ensembl:ENSP00000257566 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:tbx3_human(display_long)|uniprotkb:TBX3(gene name)|psi-mi:TBX3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_005987.3|refseq:NP_057653.3|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060596"(mammary placode formation)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072105"(ureteric peristalsis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090398"(cellular senescence)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:1905072"(cardiac jelly development)|go:"GO:1905222"(atrioventricular canal morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:2000137"(negative regulation of cell proliferation involved in heart morphogenesis)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR022582|go:"GO:0046884"(follicle-stimulating hormone secretion)|interpro:IPR036960|mint:O15119|rcsb pdb:1H6F|go:"GO:0048332"(mesoderm morphogenesis)|ensembl:ENSG00000135111(gene)|ensembl:ENST00000257566(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003205"(cardiac chamber development)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007569"(cell aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010159"(specification of animal organ position)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021761"(limbic system development)|go:"GO:0030539"(male genitalia development)|go:"GO:0030540"(female genitalia development)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0032275"(luteinizing hormone secretion)|genbank_protein_gi:119618476(identity)|refseq:EAW98070(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 12 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:XFc+uKzh/fepV1LnuCMXgShOuj49606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O14744 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-351098|uniprotkb:Q6IBR1|uniprotkb:A8MZ91|uniprotkb:Q9UKH1|uniprotkb:B5BU10|uniprotkb:D3DS33|ensembl:ENSP00000319169|uniprotkb:A8MTP3|uniprotkb:B4DX49|uniprotkb:B4DY30|uniprotkb:E2QRE7 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:anm5_human(display_long)|uniprotkb:PRMT5(gene name)|psi-mi:PRMT5(display_short)|uniprotkb:IBP72(gene name synonym)|uniprotkb:JBP1(gene name synonym)|uniprotkb:HRMT1L5(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym)|uniprotkb:72 kDa ICln-binding protein(gene name synonym)|uniprotkb:SKB1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001034708.1|refseq:NP_006100.2|refseq:NP_001269882.1|refseq:NP_001269884.1|refseq:NP_001269885.1|ensembl:ENSG00000100462(gene)|ensembl:ENST00000324366(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0097421"(liver regeneration)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR025799|interpro:IPR029063|interpro:IPR035075|interpro:IPR035247|interpro:IPR035248|mint:O14744|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858|reactome:R-HSA-6804760|go:"GO:1904992"(positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway)|dip:DIP-33172N|refseq:NP_006100(identity)|genbank_protein_gi:20070220(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 8 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:EwePjCDiU/fiuKOO+wnoYQ8I57I9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O14709 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-1105341|uniprotkb:B2RAH8|intact:EBI-28979725|ensembl:ENSP00000345809|ensembl:ENSP00000379370|ensembl:ENSP00000485709|ensembl:ENSP00000486739|uniprotkb:Q86VG0 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:zn197_human(display_long)|uniprotkb:ZNF197(gene name)|psi-mi:ZNF197(display_short)|uniprotkb:ZNF166(gene name synonym)|uniprotkb:ZKSCAN9(gene name synonym)|uniprotkb:ZnF20(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 9(gene name synonym)|uniprotkb:pVHL-associated KRAB domain-containing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_008922.1|ensembl:ENSP00000345809|ensembl:ENST00000383744|ensembl:ENSP00000373250|ensembl:ENST00000383745|ensembl:ENSP00000373251|ensembl:ENSP00000379370|ensembl:ENST00000627517|ensembl:ENSP00000487305|ensembl:ENST00000627752|ensembl:ENSP00000486777|ensembl:ENSP00000486739|ensembl:ENSP00000485709|ensembl:ENSG00000186448(gene)|ensembl:ENSG00000281709(gene)|ensembl:ENST00000344387(transcript)|ensembl:ENST00000396058(transcript)|ensembl:ENST00000627845(transcript)|ensembl:ENST00000628172(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|refseq:NP_001020026.1|refseq:NP_001310222.1|refseq:NP_001310223.1|genbank_protein_gi:487838(identity)|refseq:AAA36817(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 8 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:unL4jqiHbHrAu1kxsrYGk0nsTG49606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:O00571 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N|genbank_protein_gi:301171467(identity)|refseq:NP_001180345(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 7 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:H0UI45 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14405226 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:h0ui45_human(display_long)|uniprotkb:MICAL1(gene name)|psi-mi:MICAL1(display_short)|uniprotkb:hCG_34125(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) interpro:IPR022735|genbank_protein_gi:119588936(identity)|refseq:EAW68530(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 10 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:lnTzunMjGHOYsyBVr4+7CwaozlA9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:B7ZMM1 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14405224 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:b7zmm1_human(display_long)|uniprotkb:CLEC4F(gene name)|psi-mi:CLEC4F(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0016021"(integral component of membrane)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033989|refseq:NP_001244956.1|genbank_protein_gi:219518346(identity)|refseq:AAI44653(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 10 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:aLSrYHwkPpE/T+jOe2zl0VIl0nI9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:B7ZM74 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14405222|ensembl:ENSP00000482144 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:b7zm74_human(display_long)|uniprotkb:STPG3(gene name)|psi-mi:STPG3(display_short)|uniprotkb:LOC441476(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) ensembl:ENSG00000197768(gene)|ensembl:ENST00000620243(transcript)|interpro:IPR010736(Protein of unknown function DUF1309)|refseq:NP_001243630.1|genbank_protein_gi:219521795(identity)|refseq:AAI44312(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 19 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:O5svB97j5hsUhRRqlBQdOjRoe349606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:B7ZM21 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14405220 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:b7zm21_human(display_long)|uniprotkb:ZFP2(gene name)|psi-mi:ZFP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) interpro:IPR036236|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|genbank_protein_gi:219518184(identity)|refseq:AAI44214(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 11 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:Ujk47nDKROTiVsGyKgvrO01YNOI9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:B3GQS7 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404728 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:b3gqs7_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:60 kDa heat shock protein, mitochondrial(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0005524"(ATP binding)|go:"GO:0009409"(response to cold)|go:"GO:0016853"(isomerase activity)|go:"GO:0042026"(protein refolding)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410|genbank_protein_gi:189502784(identity)|refseq:ACE06961(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 10 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:6dR9LqOyBr6cWqH+8sbBEZU2WDE9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:A8MW92 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-2560834|uniprotkb:Q9H702|uniprotkb:Q86W43|uniprotkb:A8MZC9|uniprotkb:Q96BT0|uniprotkb:Q9HBK3|uniprotkb:Q9NYR3|uniprotkb:Q9Y381|intact:EBI-2797510|uniprotkb:Q86U89|ensembl:ENSP00000378784|ensembl:ENSP00000482945 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:p20l1_human(display_long)|uniprotkb:PHF20L1(gene name)|psi-mi:PHF20L1(display_short)|uniprotkb:CGI-72(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_057102.4|refseq:NP_940915.1|ensembl:ENSG00000129292(gene)|ensembl:ENST00000395386(transcript)|ensembl:ENST00000622263(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR002999(Tudor)|interpro:IPR004092(Mbt repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014002(Tudor-like, plant)|interpro:IPR019786|interpro:IPR022255|interpro:IPR040477|interpro:IPR043449|mint:A8MW92|rcsb pdb:2EQM|rcsb pdb:2EQU|rcsb pdb:2JTF|rcsb pdb:6L10|rcsb pdb:6L1C|rcsb pdb:6L1F|rcsb pdb:6L1I|rcsb pdb:6L1P|rcsb pdb:6L0X|refseq:XP_016869006.1|genbank_protein_gi:39653325(identity)|refseq:NP_940915(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 18 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:rkzmf0OHtpMATZ2P0uhZu0GR94E9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:A8K8P3 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-743371|uniprotkb:A1L373|uniprotkb:A1L387|uniprotkb:A2A2L2|uniprotkb:B1AKL9|uniprotkb:O60289|uniprotkb:Q2TAN8|uniprotkb:Q5W1B5|uniprotkb:Q86TK0|uniprotkb:Q8N8C1|uniprotkb:Q8WU14|uniprotkb:Q8N4U8|uniprotkb:B5MDB7|intact:EBI-2803099|uniprotkb:B7Z1V6|uniprotkb:B7Z8G3|uniprotkb:B7ZBE2|uniprotkb:B7ZBE3|ensembl:ENSP00000383145 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:sfi1_human(display_long)|uniprotkb:KIAA0542(gene name synonym)|uniprotkb:SFI1(gene name)|psi-mi:SFI1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001245254.1|refseq:NP_001245255.1|refseq:NP_001245256.1|refseq:NP_001007468.1|refseq:NP_055590.2|ensembl:ENSG00000198089(gene)|ensembl:ENST00000400288(transcript)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0019902"(phosphatase binding)|interpro:IPR030516|mint:A8K8P3|rcsb pdb:2K2I|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_006724453.1|refseq:XP_016884640.1|refseq:XP_016884643.1|genbank_protein_gi:119580385(identity)|refseq:EAW59981(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:hNob4sTZSjcaRJJr1FFkHj9leWY9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:A0MZ66 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-308778|uniprotkb:A8MYU7|uniprotkb:B3KRD3|uniprotkb:B3KRH2|uniprotkb:B3KTE0|uniprotkb:B3KTJ7|uniprotkb:B3KTJ8|uniprotkb:B4E3U1|uniprotkb:Q68DG1|uniprotkb:Q6PIM5|uniprotkb:Q9NUV0|intact:EBI-1057684|uniprotkb:Q9HCH4|ensembl:ENSP00000347532|uniprotkb:B7Z7Z9 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:shot1_human(display_long)|uniprotkb:SHTN1(gene name)|psi-mi:SHTN1(display_short)|uniprotkb:KIAA1598(gene name synonym)|uniprotkb:Shootin1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) refseq:NP_001120683.1|refseq:NP_060800.2|refseq:XP_016871951.1|ensembl:ENSG00000187164(gene)|ensembl:ENST00000355371(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019894"(kinesin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031252"(cell leading edge)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061163"(endoplasmic reticulum polarization)|go:"GO:0061573"(actin filament bundle retrograde transport)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR024849|reactome:R-HSA-437239|refseq:NP_001245227.1|refseq:NP_001245228.1|refseq:NP_001245229.1|ensembl:ENST00000260777|ensembl:ENSP00000260777|ensembl:ENSP00000347532|ensembl:ENST00000392901|ensembl:ENSP00000376635|ensembl:ENST00000392903|ensembl:ENSP00000376636|ensembl:ENST00000615301|ensembl:ENSP00000480109|genbank_protein_gi:119569823(identity)|refseq:EAW49438(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 8 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:dQ89YPXx+jJMJjl6/Dk3AMLWtVQ9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 intact:EBI-14405218 intact:EBI-8430745|intact:MINT-8081619 - psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:a0a087wv23(display_short)|psi-mi:EBI-14405218(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) uniprotkb:A0A087WV23(uniprot-removed-ac)|genbank_protein_gi:28194067(identity)|refseq:AAO33388(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|comment:This prey was identified in band no. 20 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 - - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:A0A024R382 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14405216 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:a0a024r382_human(display_long)|uniprotkb:CNDP2(gene name)|psi-mi:CNDP2(display_short)|uniprotkb:hCG_16050(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0016787"(hydrolase activity)|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|genbank_protein_gi:119586957(identity)|refseq:EAW66553(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 17 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:KVse49MRV5oVFm4/V8MF7+A0DtU9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:A0A024R0Q3 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-14404722 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:a0a024r0q3_human(display_long)|uniprotkb:ZNF224(gene name)|psi-mi:ZNF224(display_short)|uniprotkb:hCG_1647772(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14405248|imex:IM-25425-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|genbank_protein_gi:94483577(identity)|refseq:ABF21236(identity) go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|genbank_protein_gi:119577656(identity)|refseq:EAW57252(identity) - comment:mint|comment:This bait was identified in band no. 4 on the 1D SDS-PAGE in figure 1A. comment:This prey was identified in band no. 3 on the 1D SDS-PAGE in figure 1A. figure legend:Supplementary table 1, fig. 1A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2018/07/23 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:b4ZsQLia6Z1fuvCuQkkPiyeHg4o9606 - false flag tag:c-c|mutation:627-627 - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P03427 uniprotkb:P49411 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14462431|imex:IM-25425-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - comment:mint - figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2017/05/22 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rigid:fFL5JKXR1Um0QeVfL0v080OwGD8 false flag tag:c-c|mutation increasing interaction strength:627-627 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49411 uniprotkb:C8XKY2 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 intact:EBI-14462487 psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:c8xky2_9infa(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:669984(669984)|taxid:669984(Influenza A virus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14462474|imex:IM-25425-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|interpro:IPR037258 - - - figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2017/05/22 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rogid:bvuW8EBtcUZ7G5rxDoQ3oTWVbi0669984 rigid:WtROLxMPFGr8+xZQ2I7PxZyE3Gk false - flag tag:c-c|mutation increasing interaction strength:590-591 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49411 uniprotkb:A0A0K1LEV0 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 intact:EBI-14462533 psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:a0a0k1lev0_9infa(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:1663996("A/Anhui/1-YK_RG01/2013(H7N9)")|taxid:1663996(Influenza A virus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14462512|imex:IM-25425-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|interpro:IPR037258 - - - figure legend:2E, S3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2017/05/22 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rogid:7aTMeJBWcoaVVOPEbQo6yFb2Gx01663996 rigid:TohvvSwKRdYONW25t8krbWbTqmg false - flag tag:c-c|mutation causing an interaction:627-627 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P03427 uniprotkb:Q86UT6 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-3893071|uniprotkb:A8K6Q1|uniprotkb:B3KPK2|uniprotkb:B3KTA2|uniprotkb:Q7RTR3|uniprotkb:Q96D51|uniprotkb:Q9H724|ensembl:ENSP00000292199|ensembl:ENSP00000386851|ensembl:ENSP00000386858|ensembl:ENSP00000387334 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:nlrx1_human(display_long)|uniprotkb:NLRX1(gene name)|psi-mi:NLRX1(display_short)|uniprotkb:NOD26(gene name synonym)|uniprotkb:NOD5(gene name synonym)|uniprotkb:NOD9(gene name synonym)|uniprotkb:Caterpiller protein 11.3(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 26(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 5(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14576243|imex:IM-25425-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) refseq:XP_006718967.1|refseq:XP_011541282.1|refseq:NP_078894.2|dip:DIP-60637N|refseq:NP_001269072.1|refseq:NP_001269073.1|refseq:NP_001269287.1|refseq:XP_005271726.1|ensembl:ENSG00000160703(gene)|ensembl:ENST00000292199(transcript)|ensembl:ENST00000409109(transcript)|ensembl:ENST00000409265(transcript)|ensembl:ENST00000409991(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050728"(negative regulation of inflammatory response)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR032675|rcsb pdb:3UN9|reactome:R-HSA-168928|reactome:R-HSA-936440|go:"GO:0030054"(cell junction) - comment:mint - figure legend:S8A|comment:"Interaction with NLRX1 is barely detectable when using the WT (human signature) form of PB2."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2017/05/22 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:w+BOLVATt2ey/lEP6RY9zP2q/gc9606 rigid:RxRxTolOtiWJmGqpT8+x4etVdd8 false flag tag:c-c|mutation increasing interaction strength:627-627 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P03427 uniprotkb:P49411 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14576243|imex:IM-25425-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - comment:mint - figure legend:S8A|comment:"Interaction with NLRX1 is barely detectable when using the WT (human signature) form of PB2."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2017/05/22 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rigid:RxRxTolOtiWJmGqpT8+x4etVdd8 false flag tag:c-c|mutation increasing interaction strength:627-627 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P03427 uniprotkb:P49411 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14988794|imex:IM-25425-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - comment:mint - figure legend:S2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick-df-1)|taxid:9031(df-1_chick embryonic fibroblasts) - 2016/07/20 2017/05/24 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rigid:fFL5JKXR1Um0QeVfL0v080OwGD8 false flag tag:c-c|mutation:627-627 tandem tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P03427 uniprotkb:P49411 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14519285|imex:IM-25425-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - comment:mint - figure legend:2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2017/05/22 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rigid:fFL5JKXR1Um0QeVfL0v080OwGD8 false flag tag:c-c|mutation increasing interaction strength:627-627 tandem tag:c-c|necessary binding region:1-253|sufficient binding region:1-253 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P49411 uniprotkb:P03427 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 intact:EBI-8430745|intact:MINT-8081619 psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14584285|imex:IM-25425-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) - - comment:mint figure legend:S8B|comment:The amount of NKRX1 co-immunoprecipitated with TUFM decreases as the amount of PB2 is increased.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2017/05/24 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rigid:RxRxTolOtiWJmGqpT8+x4etVdd8 false flag tag:c-c mutation:627-627|tandem tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P49411 uniprotkb:Q86UT6 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 intact:EBI-3893071|uniprotkb:A8K6Q1|uniprotkb:B3KPK2|uniprotkb:B3KTA2|uniprotkb:Q7RTR3|uniprotkb:Q96D51|uniprotkb:Q9H724|ensembl:ENSP00000292199|ensembl:ENSP00000386851|ensembl:ENSP00000386858|ensembl:ENSP00000387334 psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:nlrx1_human(display_long)|uniprotkb:NLRX1(gene name)|psi-mi:NLRX1(display_short)|uniprotkb:NOD26(gene name synonym)|uniprotkb:NOD5(gene name synonym)|uniprotkb:NOD9(gene name synonym)|uniprotkb:Caterpiller protein 11.3(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 26(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 5(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-14584285|imex:IM-25425-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 refseq:XP_006718967.1|refseq:XP_011541282.1|refseq:NP_078894.2|dip:DIP-60637N|refseq:NP_001269072.1|refseq:NP_001269073.1|refseq:NP_001269287.1|refseq:XP_005271726.1|ensembl:ENSG00000160703(gene)|ensembl:ENST00000292199(transcript)|ensembl:ENST00000409109(transcript)|ensembl:ENST00000409265(transcript)|ensembl:ENST00000409991(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050728"(negative regulation of inflammatory response)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR032675|rcsb pdb:3UN9|reactome:R-HSA-168928|reactome:R-HSA-936440|go:"GO:0030054"(cell junction) - - - figure legend:S8B|comment:The amount of NKRX1 co-immunoprecipitated with TUFM decreases as the amount of PB2 is increased.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2017/05/24 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rogid:w+BOLVATt2ey/lEP6RY9zP2q/gc9606 rigid:RxRxTolOtiWJmGqpT8+x4etVdd8 false flag tag:c-c tandem tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q86UT6 uniprotkb:P49411 intact:EBI-3893071|uniprotkb:A8K6Q1|uniprotkb:B3KPK2|uniprotkb:B3KTA2|uniprotkb:Q7RTR3|uniprotkb:Q96D51|uniprotkb:Q9H724|ensembl:ENSP00000292199|ensembl:ENSP00000386851|ensembl:ENSP00000386858|ensembl:ENSP00000387334 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:nlrx1_human(display_long)|uniprotkb:NLRX1(gene name)|psi-mi:NLRX1(display_short)|uniprotkb:NOD26(gene name synonym)|uniprotkb:NOD5(gene name synonym)|uniprotkb:NOD9(gene name synonym)|uniprotkb:Caterpiller protein 11.3(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 26(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 5(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 9(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14988752|imex:IM-25425-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006718967.1|refseq:XP_011541282.1|refseq:NP_078894.2|dip:DIP-60637N|refseq:NP_001269072.1|refseq:NP_001269073.1|refseq:NP_001269287.1|refseq:XP_005271726.1|ensembl:ENSG00000160703(gene)|ensembl:ENST00000292199(transcript)|ensembl:ENST00000409109(transcript)|ensembl:ENST00000409265(transcript)|ensembl:ENST00000409991(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050728"(negative regulation of inflammatory response)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR032675|rcsb pdb:3UN9|reactome:R-HSA-168928|reactome:R-HSA-936440|go:"GO:0030054"(cell junction) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - - - figure legend:S8B|comment:The amount of NKRX1 co-immunoprecipitated with TUFM decreases as the amount of PB2 is increased.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/07/20 2017/05/24 rogid:w+BOLVATt2ey/lEP6RY9zP2q/gc9606 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rigid:auPqtuH9DqajOWlHfz1V+il3Ayw false tandem tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P03427 uniprotkb:P49411 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-14519358|imex:IM-25425-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 go:"GO:0005739"(mitochondrion) comment:mint - figure legend:4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line) - 2016/07/20 2017/05/22 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rigid:fFL5JKXR1Um0QeVfL0v080OwGD8 false mutation with no effect:627-627 - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P03427 uniprotkb:P49411 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14554587|imex:IM-25425-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 go:"GO:0005739"(mitochondrion) comment:mint - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2016/07/20 2017/05/22 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rigid:fFL5JKXR1Um0QeVfL0v080OwGD8 false mutation increasing interaction strength:627-627 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P03427 uniprotkb:P49411 intact:EBI-8430745|intact:MINT-8081619 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2017) pubmed:28611246|imex:IM-25425 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14988816|imex:IM-25425-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - comment:mint - figure legend:S2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick-df-1)|taxid:9031(df-1_chick embryonic fibroblasts) - 2016/07/20 2017/05/24 rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rigid:fFL5JKXR1Um0QeVfL0v080OwGD8 false flag tag:c-c|mutation:627-627 tandem tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)