#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B ensembl:ENSG00000111276 uniprotkb:Q6W2J9 intact:EBI-2891650 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552270|imex:IM-25601-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:3D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-b-cell)|taxid:9606(Homo sapiens B cell) - 2016/08/19 2016/09/30 - rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 - false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P41182 ensembl:ENSG00000111276 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 intact:EBI-2891650 psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552338|imex:IM-25601-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 - - - - figure legend:3D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-b-cell)|taxid:9606(Homo sapiens B cell) - 2016/08/19 2016/09/30 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 - - false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P41182 ensembl:ENSG00000057657 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 intact:EBI-10049836 psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:prdm1_human_gene(display_short)|psi-mi:ENSG00000057657(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552345|imex:IM-25601-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 - - - - figure legend:3E|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-b-cell)|taxid:9606(Homo sapiens B cell) - 2016/08/19 2016/09/30 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 - - false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6W2J9 ensembl:ENSG00000057657 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-10049836 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:prdm1_human_gene(display_short)|psi-mi:ENSG00000057657(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552352|imex:IM-25601-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - - figure legend:3Ei|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-b-cell)|taxid:9606(Homo sapiens B cell) - 2016/08/19 2016/09/30 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 - - false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P41182 ensembl:ENSG00000168283 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 intact:EBI-12555205 psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|ensembl:bmi1_human_gene(shortlabel)|psi-mi:ENSG00000168283(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12555199|imex:IM-25601-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 refseq:NP_001190991.1|refseq:NP_005171.4 - - - figure legend:Supp 3C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-b-cell)|taxid:9606(Homo sapiens B cell) - 2016/08/19 2016/10/04 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 - - false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6W2J9 ensembl:ENSG00000168283 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-12555205 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|ensembl:bmi1_human_gene(shortlabel)|psi-mi:ENSG00000168283(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12555215|imex:IM-25601-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_001190991.1|refseq:NP_005171.4 - - - figure legend:Supp 3C-2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-b-cell)|taxid:9606(Homo sapiens B cell) - 2016/08/19 2016/10/04 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 - - false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P41182 ensembl:ENSG00000111276 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 intact:EBI-2891650 psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552395|imex:IM-25601-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 - - - - figure legend:5A, Supp 5B|causality statement:CHEMBL2204995 decreases binding of P41182 to ENSG00000111276|causality statement:"CHEBI:133537 decreases binding of P41182 to ENSG00000111276"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 - - false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000057657 uniprotkb:P41182 intact:EBI-10049836 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 psi-mi:prdm1_human_gene(display_short)|psi-mi:ENSG00000057657(display_long) psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552389|imex:IM-25601-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 - - - figure legend:5A, Supp 5B|causality statement:"CHEBI:133537 decreases binding of P41182 to ENSG00000057657"|causality statement:CHEMBL2204995 causes no change in the binding of P41182 to ENSG00000057657|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 - rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 - false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q6W2J9 ensembl:ENSG00000057657 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-10049836 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:prdm1_human_gene(display_short)|psi-mi:ENSG00000057657(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552407|imex:IM-25601-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - - figure legend:5A, 6I, Supp 5B|causality statement:CHEMBL2204995 decreases binding of Q6W2J9 to ENSG00000057657|causality statement:"CHEBI:133537 decreases binding of Q6W2J9 to ENSG00000057657"|causality statement:Q9HC52 increases the binding of Q6W2J9 to ENSG00000057657|antagonist:CBX8 shRNA|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 - - false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000111276 uniprotkb:Q15910 intact:EBI-2891650 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552420|imex:IM-25601-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - - figure legend:5Ai, Supp 5B|causality statement:CHEMBL2204995 decreases binding of Q15910 to ENSG00000111276|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 - rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 - false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000057657 uniprotkb:Q15910 intact:EBI-10049836 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:prdm1_human_gene(display_short)|psi-mi:ENSG00000057657(display_long) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552426|imex:IM-25601-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - - figure legend:5Aii, Supp 5B|causality statement:CHEMBL2204995 decreases binding of Q15910 to ENSG00000057657|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 - rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 - false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q6W2J9 ensembl:ENSG00000111276 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-2891650 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552512|imex:IM-25601-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - - figure legend:5Aiii, 6I, Supp fig 5B|causality statement:"CHEBI:133537 decreases binding of Q6W2J9 to ENSG00000111276"|causality statement:CHEMBL2204995 decreases binding of Q6W2J9 to ENSG00000111276|causality statement:Q9HC52 increases the binding of Q6W2J9 to ENSG00000111276|antagonist:CBX8 shRNA|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 - - false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000124762 uniprotkb:Q9HC52 intact:EBI-1550784 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:cdkn1a_human_gene(display_short)|psi-mi:ENSG00000124762(display_long) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553065|imex:IM-25601-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N - - - figure legend:6G-1|antagonist:CHEMBL2204995 -GSK343|causality statement:CHEMBL2204995 decreases the binding of Q9HC52 to ENSG00000124762|causality statement:Q9HC52 decreases expression at RNA level of ENSG00000124762|causality statement:CHEMBL2204995 increases expression at RNA level of ENSG00000124762|causality statement:"CHEBI:133537 increases expression at RNA level of ENSG00000124762"|causality statement:"CHEBI:133537 and CHEMBL2204995 synergistically increases expression at RNA level of ENSG00000124762"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/10/03 - rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 - false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000111276 uniprotkb:Q9HC52 intact:EBI-2891650 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553073|imex:IM-25601-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N - - - figure legend:6G-2|antagonist:CHEMBL2204995 -GSK343|causality statement:CHEMBL2204995 decreases the binding of Q9HC52 to ENSG00000111276|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/10/03 - rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 - false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000057657 uniprotkb:Q9HC52 intact:EBI-10049836 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:prdm1_human_gene(display_short)|psi-mi:ENSG00000057657(display_long) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553133|imex:IM-25601-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N - - - figure legend:6G-3|antagonist:CHEMBL2204995 -GSK343|causality statement:CHEMBL2204995 decreases the binding of Q9HC52 to ENSG00000057657|causality statement:Q9HC52 decreases expression at RNA level of ENSG00000057657|causality statement:"CHEBI:133537 and CHEMBL2204995 synergistically increases expression at RNA level of ENSG00000057657"|causality statement:"CHEBI:133537 increases expression at RNA level of ENSG00000057657"|causality statement:CHEMBL2204995 increases expression at RNA level of ENSG00000057657|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/10/03 - rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 - false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000137265 uniprotkb:Q9HC52 intact:EBI-12553149 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 uniprotkb:IRF4(gene name)|psi-mi:IRF4(display_short)|uniprotkb:MUM1(gene name synonym)|ensembl:irf4_human_gene(shortlabel)|psi-mi:ENSG00000137265(display_long) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553141|imex:IM-25601-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) refseq:NP_001182215.1|refseq:NP_002451.2 ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N - - - figure legend:6G-4|antagonist:CHEMBL2204995 -GSK343|causality statement:CHEMBL2204995 decreases the binding of Q9HC52 to ENSG00000137265|causality statement:Q9HC52 decreases expression at RNA level of ENSG00000137265|causality statement:"CHEBI:133537 increases expression at RNA level of ENSG00000137265"|causality statement:CHEMBL2204995 increases expression at RNA level of ENSG00000137265|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/10/03 - rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 - false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000116017 uniprotkb:Q9HC52 intact:EBI-12553163 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 uniprotkb:ARID3A(gene name)|psi-mi:ARID3A(display_short)|uniprotkb:DRIL1(gene name synonym)|uniprotkb:DRIL3(gene name synonym)|uniprotkb:DRX(gene name synonym)|uniprotkb:E2FBP1(gene name synonym)|ensembl:ari3a_human_gene(shortlabel)|psi-mi:ENSG00000116017(display_long) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553155|imex:IM-25601-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) refseq:NP_005215.1|refseq:XP_005259570.1|refseq:XP_005259571.1 ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N - - - figure legend:6G-5|antagonist:CHEMBL2204995 -GSK343|causality statement:CHEMBL2204995 decreases the binding of Q9HC52 to ENSG00000116017|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/10/03 - rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 - false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000179361 uniprotkb:Q9HC52 intact:EBI-12553181 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 uniprotkb:ARID3B(gene name)|psi-mi:ARID3B(display_short)|uniprotkb:BDP(gene name synonym)|uniprotkb:DRIL2(gene name synonym)|ensembl:ari3b_human_gene(shortlabel)|psi-mi:ENSG00000179361(display_long) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553173|imex:IM-25601-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) refseq:NP_001294868.1|refseq:NP_006456.1 ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N - - - figure legend:6G-6|antagonist:CHEMBL2204995 -GSK343|causality statement:CHEMBL2204995 decreases the binding of Q9HC52 to ENSG00000179361|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/10/03 - rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 - false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000124762 uniprotkb:Q6W2J9 intact:EBI-1550784 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:cdkn1a_human_gene(display_short)|psi-mi:ENSG00000124762(display_long) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553192|imex:IM-25601-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:"6I-1 (Supp 5B)"|antagonist:CBX8 shRNA|causality statement:Q9HC52 increases the binding of Q6W2J9 to ENSG00000124762|comment:Supplementary figure 5B appears to show minimal binding between BCOR and CDKN1A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/10/03 - rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 - false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000137265 uniprotkb:Q6W2J9 intact:EBI-12553149 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 uniprotkb:IRF4(gene name)|psi-mi:IRF4(display_short)|uniprotkb:MUM1(gene name synonym)|ensembl:irf4_human_gene(shortlabel)|psi-mi:ENSG00000137265(display_long) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553228|imex:IM-25601-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) refseq:NP_001182215.1|refseq:NP_002451.2 ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:6I-4, Supp 5B|antagonist:CBX8 shRNA|causality statement:Q9HC52 increases the binding of Q6W2J9 to ENSG00000137265|causality statement:"CHEBI:133537 decreases binding of Q6W2J9 to ENSG00000137265"|causality statement:CHEMBL2204995 decreases binding of Q6W2J9 toENSG00000137265|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/10/03 - rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 - false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000116017 uniprotkb:Q6W2J9 intact:EBI-12553163 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 uniprotkb:ARID3A(gene name)|psi-mi:ARID3A(display_short)|uniprotkb:DRIL1(gene name synonym)|uniprotkb:DRIL3(gene name synonym)|uniprotkb:DRX(gene name synonym)|uniprotkb:E2FBP1(gene name synonym)|ensembl:ari3a_human_gene(shortlabel)|psi-mi:ENSG00000116017(display_long) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553236|imex:IM-25601-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) refseq:NP_005215.1|refseq:XP_005259570.1|refseq:XP_005259571.1 ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:6I-5, Supp 5B|antagonist:CBX8 shRNA|causality statement:Q9HC52 increases the binding of Q6W2J9 to ENSG00000116017|causality statement:"CHEBI:133537 decreases binding of Q6W2J9 to ENSG00000116017"|causality statement:CHEMBL2204995 decreases binding of Q6W2J9 to ENSG00000116017|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/10/03 - rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 - false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q15910 ensembl:ENSG00000111276 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-2891650 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552401|imex:IM-25601-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - - - figure legend:5A-1|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 - - false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q15910 uniprotkb:Q6W2J9 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552401|imex:IM-25601-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:5A-1|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 - false - - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:P41182 uniprotkb:Q15910 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552458|imex:IM-25601-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - - figure legend:5A-8|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 - false - - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:P41182 ensembl:ENSG00000057657 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 intact:EBI-10049836 psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:prdm1_human_gene(display_short)|psi-mi:ENSG00000057657(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552458|imex:IM-25601-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 - - - - figure legend:5A-8|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 - - false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q6W2J9 uniprotkb:Q15910 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552446|imex:IM-25601-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - - figure legend:5A-7|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 - false - - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q6W2J9 ensembl:ENSG00000057657 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-10049836 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:prdm1_human_gene(display_short)|psi-mi:ENSG00000057657(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552446|imex:IM-25601-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - - figure legend:5A-7|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 - - false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q6W2J9 uniprotkb:Q15910 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552464|imex:IM-25601-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - - figure legend:5A-3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 - false - - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q6W2J9 ensembl:ENSG00000111276 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-2891650 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552464|imex:IM-25601-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - - figure legend:5A-3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 - - false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q15910 uniprotkb:P41182 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552440|imex:IM-25601-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 - - - figure legend:5A-2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 - false - - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q15910 ensembl:ENSG00000111276 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-2891650 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552440|imex:IM-25601-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - - - figure legend:5A-2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 - - false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q15910 ensembl:ENSG00000057657 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-10049836 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:prdm1_human_gene(display_short)|psi-mi:ENSG00000057657(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552479|imex:IM-25601-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - - - figure legend:5A-5|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 - - false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q15910 uniprotkb:Q6W2J9 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552479|imex:IM-25601-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:5A-5|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 - false - - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q15910 uniprotkb:P41182 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552487|imex:IM-25601-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 - - - figure legend:5A-6|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 - false - - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q15910 ensembl:ENSG00000057657 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-10049836 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:prdm1_human_gene(display_short)|psi-mi:ENSG00000057657(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552487|imex:IM-25601-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - - - figure legend:5A-6|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 - - false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:P41182 uniprotkb:Q15910 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552497|imex:IM-25601-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - - figure legend:5A-4|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 - false - - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:P41182 ensembl:ENSG00000111276 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 intact:EBI-2891650 psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552497|imex:IM-25601-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 - - - - figure legend:5A-4|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/09/30 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 - - false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000111276 uniprotkb:Q15910 intact:EBI-2891650 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552530|imex:IM-25601-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - - figure legend:5 B/C-1|antagonist:"EZH2 inhibitor: GSK343 (CHEMBL2204995)"|causality statement:CHEMBL2204995 decreases binding of Q15910 to ENSG00000111276|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sudhl-6)|taxid:9606(human) - 2016/08/19 2016/09/30 - rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 - false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000111276 uniprotkb:O75530 intact:EBI-2891650 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552538|imex:IM-25601-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - - figure legend:5 B/C-2|antagonist:"EZH2 inhibitor: GSK343 (CHEMBL2204995)"|causality statement:CHEMBL2204995 decreases binding of O75530 to ENSG00000111276|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sudhl-6)|taxid:9606(human) - 2016/08/19 2016/09/30 - rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 - false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000111276 uniprotkb:Q15022 intact:EBI-2891650 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552546|imex:IM-25601-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - - figure legend:5 B/C-3|antagonist:"EZH2 inhibitor: GSK343 (CHEMBL2204995)"|causality statement:CHEMBL2204995 decreases binding of Q15022 to ENSG00000111276|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sudhl-6)|taxid:9606(human) - 2016/08/19 2016/09/30 - rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 - false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000111276 uniprotkb:Q6W2J9 intact:EBI-2891650 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552556|imex:IM-25601-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:5 B/C-4|antagonist:"EZH2 inhibitor: GSK343 (CHEMBL2204995)"|causality statement:CHEMBL2204995 decreases binding of Q6W2J9 to ENSG00000111276|antagonist:"BCL6 inhibitor FX1:CHEBI:133537"|causality statement:"CHEBI:133537 decreases binding of Q6W2J9 to ENSG00000111276"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sudhl-6)|taxid:9606(human) - 2016/08/19 2016/09/30 - rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 - false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000111276 uniprotkb:Q99496 intact:EBI-2891650 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552564|imex:IM-25601-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - - figure legend:5 B/C-5|antagonist:"EZH2 inhibitor: GSK343 (CHEMBL2204995)"|causality statement:CHEMBL2204995 decreases binding of Q99496 to ENSG00000111276|antagonist:"BCL6 inhibitor : FX1 -CHEBI:133537"|causality statement:"CHEBI:133537 decreases binding of Q99496 to ENSG00000111276"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sudhl-6)|taxid:9606(human) - 2016/08/19 2016/09/30 - rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 - false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q8NHM5 ensembl:ENSG00000111276 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 intact:EBI-2891650 psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552572|imex:IM-25601-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 - - - - figure legend:5 B/C-6|antagonist:"EZH2 inhibitor: GSK343 (CHEMBL2204995)"|causality statement:CHEMBL2204995 decreases binding of Q8NHM5 to ENSG00000111276|antagonist:"BCL6 inhibitor FX1:CHEBI:133537"|causality statement:"CHEBI:133537 decreases binding of Q8NHM5 to ENSG00000111276"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sudhl-6)|taxid:9606(human) - 2016/08/19 2016/09/30 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 - - false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000111276 uniprotkb:Q9BSM1 intact:EBI-2891650 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552581|imex:IM-25601-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 - - - figure legend:5B-7|antagonist:"EZH2 inhibitor: GSK343 (CHEMBL2204995)"|causality statement:CHEMBL2204995 decreases binding of Q9BSM1 to ENSG00000111276|antagonist:"BCL6 inhibitor : FX1 -CHEBI:133537"|causality statement:"CHEBI:133537 decreases binding of Q9BSM1 to ENSG00000111276"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sudhl-6)|taxid:9606(human) - 2016/08/19 2016/09/30 - rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 - false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:P41182 ensembl:ENSG00000111276 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 intact:EBI-2891650 psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:cdkn1b_human_gene(display_short)|psi-mi:ENSG00000111276(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552597|imex:IM-25601-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 - - - - figure legend:5 B/C-8|antagonist:"BCL6 inhibitor : FX1 -CHEBI:133537"|causality statement:"CHEBI:133537 decreases the binding of P41182 to ENSG00000111276"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sudhl-6)|taxid:9606(human) - 2016/08/19 2016/09/30 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 - - false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q9BSM1 uniprotkb:Q8NHM5 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552638|imex:IM-25601-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 - - - figure legend:6D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2016/08/19 2016/09/30 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rigid:gsyri/QdfKNoeJaCqIj53HEc1HQ false flag tag:?-?|myc tag:?-? myc tag:n-n - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9BSM1 uniprotkb:Q9HC52 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552638|imex:IM-25601-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N - - - figure legend:6D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2016/08/19 2016/09/30 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rigid:gsyri/QdfKNoeJaCqIj53HEc1HQ false flag tag:?-?|myc tag:?-? myc tag:n-n - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9BSM1 uniprotkb:Q99496 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552638|imex:IM-25601-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - - figure legend:6D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2016/08/19 2016/09/30 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:gsyri/QdfKNoeJaCqIj53HEc1HQ false flag tag:?-?|myc tag:?-? myc tag:n-n - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9BSM1 uniprotkb:Q6W2J9 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552638|imex:IM-25601-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:6D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2016/08/19 2016/09/30 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rigid:gsyri/QdfKNoeJaCqIj53HEc1HQ false flag tag:?-?|myc tag:?-? myc tag:n-n|sufficient binding region:1562-1755 - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9BSM1 uniprotkb:Q8NHM5 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552956|imex:IM-25601-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 - - - figure legend:6D-2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2016/08/19 2016/10/03 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rigid:iZbctJ43wHAXxbgAwFV6h7QfQEU false flag tag:?-?|myc tag:?-? myc tag:n-n - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9BSM1 uniprotkb:Q99496 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552956|imex:IM-25601-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - - figure legend:6D-2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2016/08/19 2016/10/03 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:iZbctJ43wHAXxbgAwFV6h7QfQEU false flag tag:?-?|myc tag:?-? myc tag:n-n|mutation:262-262 - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9BSM1 uniprotkb:Q6W2J9 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552956|imex:IM-25601-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:6D-2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2016/08/19 2016/10/03 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rigid:iZbctJ43wHAXxbgAwFV6h7QfQEU false flag tag:?-?|myc tag:?-? myc tag:n-n|sufficient binding region:1562-1755 - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9BSM1 uniprotkb:Q8NHM5 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552979|imex:IM-25601-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 - - - figure legend:6D-3|comment:An ile375asp mutation in CBX8 disrupted binding of this molecule.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2016/08/19 2016/11/07 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rigid:iZbctJ43wHAXxbgAwFV6h7QfQEU false myc tag:?-?|flag tag:?-? myc tag:n-n - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9BSM1 uniprotkb:Q99496 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552979|imex:IM-25601-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - - figure legend:6D-3|comment:An ile375asp mutation in CBX8 disrupted binding of this molecule.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2016/08/19 2016/11/07 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:iZbctJ43wHAXxbgAwFV6h7QfQEU false myc tag:?-?|flag tag:?-? myc tag:n-n - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9BSM1 uniprotkb:Q6W2J9 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12552979|imex:IM-25601-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:6D-3|comment:An ile375asp mutation in CBX8 disrupted binding of this molecule.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2016/08/19 2016/11/07 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rigid:iZbctJ43wHAXxbgAwFV6h7QfQEU false myc tag:?-?|flag tag:?-? myc tag:n-n|sufficient binding region:1562-1755 - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9HC52 uniprotkb:Q6W2J9 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553022|imex:IM-25601-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:6E, Supp 6C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/10/03 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rigid:LOETTg4wKsu8uzb3bE60OitRqAU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9HC52 uniprotkb:Q6W2J9 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553026|imex:IM-25601-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:6E-2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-oci-ly7)|taxid:9606(diffuse large B-cell lymphoma-DLBCL) - 2016/08/19 2016/10/03 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rigid:LOETTg4wKsu8uzb3bE60OitRqAU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9HC52 uniprotkb:Q6W2J9 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553034|imex:IM-25601-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:6E-2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sudhl-4)|taxid:9606(human sudhl-4) - 2016/08/19 2016/10/03 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rigid:LOETTg4wKsu8uzb3bE60OitRqAU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9HC52 uniprotkb:Q6W2J9 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553030|imex:IM-25601-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:6E, Supp 6C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sudhl-4)|taxid:9606(human sudhl-4) - 2016/08/19 2016/10/03 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rigid:LOETTg4wKsu8uzb3bE60OitRqAU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6W2J9 uniprotkb:Q9HC52 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553047|imex:IM-25601-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N - - - figure legend:6F-2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-b-cell)|taxid:9606(Homo sapiens B cell) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rigid:LOETTg4wKsu8uzb3bE60OitRqAU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9HC52 uniprotkb:Q6W2J9 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553051|imex:IM-25601-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:6F|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-b-cell)|taxid:9606(Homo sapiens B cell) - 2016/08/19 2016/10/03 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rigid:LOETTg4wKsu8uzb3bE60OitRqAU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6W2J9 uniprotkb:Q8NHM5 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q86XX4 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-7967766|uniprotkb:Q8NAU7|intact:UNK-5504239|uniprotkb:Q86UZ4|uniprotkb:Q9H6N9|uniprotkb:Q8N3U9|uniprotkb:Q9P228|uniprotkb:Q96JW7|uniprotkb:A2RRR8 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:fras1_human(display_long)|uniprotkb:Fraser syndrome 1 protein(gene name synonym)|uniprotkb:FRAS1(gene name)|psi-mi:FRAS1(display_short)|uniprotkb:KIAA1500(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N interpro:IPR038081|interpro:IPR039005|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR006212(Furin-like repeat)|refseq:NP_001159605.1|refseq:NP_079350.5|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0043588"(skin development)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development) - - comment:mint|function:"Defects in FRAS1 are a cause of Fraser syndrome [MIM:219000]. It is a multisystem malformation usually comprising cryptophthalmos, cutaneous syndactyly, ear abnormalities, renal agenesis and congenital heart defects" figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:nJ/4j001Lihre1n+/qvt3K6k1rg9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:O43347 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-726515|uniprotkb:Q96PU0|uniprotkb:Q96PU1|uniprotkb:Q96PU2|uniprotkb:Q96PU3|intact:EBI-28986772|ensembl:ENSP00000257552 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:msi1h_human(display_long)|uniprotkb:MSI1(gene name)|psi-mi:MSI1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_002433.1|ensembl:ENSP00000257552|refseq:XP_011536663.1|ensembl:ENSG00000135097(gene)|ensembl:ENST00000257552(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0007399"(nervous system development)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034126|interpro:IPR034130|interpro:IPR035979|reactome:R-HSA-9010553 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:41/VCaTWDXjzXSisiAoG19FFVF09606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q7Z589 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-6598631|ensembl:ENSP00000334130|ensembl:ENSP00000432327|uniprotkb:Q4G109|uniprotkb:Q8NBU6|uniprotkb:Q8TE50|uniprotkb:Q9H8I9|uniprotkb:Q9NRH0|uniprotkb:B7ZKU0|uniprotkb:B7ZKT8|uniprotkb:B7ZKU2|uniprotkb:Q17RM7 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:emsy_human(display_long)|uniprotkb:EMSY(gene name)|psi-mi:EMSY(display_short)|uniprotkb:C11orf30(gene name synonym)|uniprotkb:GL002(orf name) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_001287871.1|refseq:NP_001287872.1|refseq:NP_001287873.1|ensembl:ENST00000334736(transcript)|ensembl:ENST00000529032(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042802"(identical protein binding)|interpro:IPR005491(ENT)|interpro:IPR033482|interpro:IPR036142|mint:Q7Z589|rcsb pdb:1UTU|ensembl:ENSG00000158636(gene)|rcsb pdb:1UZ3|rcsb pdb:2FMM|refseq:NP_064578.2|ensembl:ENSP00000433634|ensembl:ENST00000533988|ensembl:ENSP00000434665|ensembl:ENSP00000334130|ensembl:ENST00000524767|ensembl:ENSP00000433205|ensembl:ENST00000525038|ensembl:ENSP00000436968|ensembl:ENST00000525919|ensembl:ENSP00000432010|ensembl:ENSP00000432327|ensembl:ENST00000533248|dip:DIP-29099N - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:AlagiKsle+RG5HUine4x/QddsJc9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q5T3I0 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-2372076|uniprotkb:Q5T3I1|uniprotkb:Q6ZUE7|uniprotkb:Q8IWG8|uniprotkb:Q9NXH4 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:gptc4_human(display_long)|uniprotkb:GPATCH4(gene name)|psi-mi:GPATCH4(display_short)|uniprotkb:GPATC4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N interpro:IPR000467(D111/G-patch)|mint:Q5T3I0|go:"GO:0003723"(RNA binding) - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:R2hFHYGQh2jmLbLg+BNATVimtNA9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q96KR1 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-2513582|ensembl:ENSP00000265069|uniprotkb:Q9Y687|uniprotkb:Q6P5A3|uniprotkb:B2RNR5|uniprotkb:Q9H6V4|uniprotkb:Q3B7X5|uniprotkb:Q05C08|uniprotkb:Q9NTI1|uniprotkb:Q86UA0|intact:EBI-2560216 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:zfr_human(display_long)|uniprotkb:ZFR(gene name)|psi-mi:ZFR(display_short)|uniprotkb:M-phase phosphoprotein homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N ensembl:ENSG00000056097(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR006561(DZF)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043519|mint:Q96KR1|ensembl:ENST00000265069(transcript)|refseq:NP_057191.2|ensembl:ENSP00000265069|dip:DIP-47293N - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:UQQP+tkUcQYka9ez6rMv2F6FXFM9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q86VM9 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-1045965|uniprotkb:Q96DG4|uniprotkb:Q96MP7|ensembl:ENSP00000301011 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:zch18_human(display_long)|uniprotkb:NHN1(gene name synonym)|uniprotkb:Nuclear protein NHN1(gene name synonym)|uniprotkb:ZC3H18(gene name)|psi-mi:ZC3H18(display_short) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_001281269.1|ensembl:ENST00000301011(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0050779"(RNA destabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR041367|mint:Q86VM9|ensembl:ENSG00000158545(gene)|ensembl:ENSP00000301011|refseq:NP_653205.3 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:H9lST8OLyCpyi5AWYqFYskL0ezI9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:O43251 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q9Y2X3 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-395469|uniprotkb:Q53SA4|uniprotkb:Q6PK08|uniprotkb:Q9P036|uniprotkb:Q9UFN3|ensembl:ENSP00000264279 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:nop58_human(display_long)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOL5(gene name synonym)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP5(gene name synonym)|uniprotkb:HSPC120(orf name) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_057018.1|ensembl:ENSG00000055044(gene)|ensembl:ENST00000264279(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|go:"GO:0016020"(membrane)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:Q9Y2X3|reactome:R-HSA-4570464|reactome:R-HSA-6790901|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|reactome:R-HSA-6791226|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070761"(pre-snoRNP complex)|dip:DIP-32926N - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:L7mE30ZNpQbKsQElFrrDMBQwG+w9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q96ME7 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-10986895|ensembl:ENSP00000347648|uniprotkb:Q53RZ7|uniprotkb:B4DSM5|uniprotkb:Q96JM0|uniprotkb:Q86XK6 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:zn512_human(display_long)|uniprotkb:ZNF512(gene name)|psi-mi:ZNF512(display_short)|uniprotkb:KIAA1805(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_001258215.1|refseq:NP_001258216.1|refseq:NP_001258217.1|refseq:NP_001258218.1|refseq:NP_001258247.1|refseq:NP_115810.2|ensembl:ENSG00000243943(gene)|ensembl:ENST00000355467(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96ME7|rcsb pdb:2CTD - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:7knJd2B0V/f95Cc0Ml8AN5bBN+A9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q9HC52 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q9UQR1 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-2688184|uniprotkb:Q58EY5|uniprotkb:O43591|uniprotkb:O00389|uniprotkb:D3DN27|ensembl:ENSP00000420448|ensembl:ENSP00000353863|ensembl:ENSP00000419322|ensembl:ENSP00000420335|uniprotkb:Q6PJ98 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:zn148_human(display_long)|uniprotkb:ZBP89(gene name synonym)|uniprotkb:Transcription factor ZBP-89(gene name synonym)|uniprotkb:Zinc finger DNA-binding protein 89(gene name synonym)|uniprotkb:ZNF148(gene name)|psi-mi:ZNF148(display_short) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_068799.2|ensembl:ENST00000360647(transcript)|ensembl:ENST00000484491(transcript)|ensembl:ENST00000485866(transcript)|ensembl:ENST00000492394(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006968"(cellular defense response)|go:"GO:0007276"(gamete generation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0021762"(substantia nigra development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9UQR1|ensembl:ENSG00000163848(gene)|refseq:NP_001335353.1|refseq:NP_001335354.1|refseq:NP_001335355.1|refseq:NP_001335356.1|refseq:NP_001335357.1|refseq:NP_001335358.1|refseq:NP_001335359.1|refseq:NP_001335360.1|refseq:NP_001335361.1|refseq:NP_001335362.1|ensembl:ENSP00000353863|ensembl:ENSP00000420335|ensembl:ENSP00000420448|ensembl:ENSP00000419322 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:2H8lAaonZqAnCWDtUN8q55+03h49606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q14157 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q2KHR3 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-11048246|uniprotkb:Q6ZUR5|uniprotkb:Q6ZU30|ensembl:ENSP00000382241 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:qser1_human(display_long)|uniprotkb:QSER1(gene name)|psi-mi:QSER1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_001070254.1|ensembl:ENSG00000060749(gene)|ensembl:ENST00000399302(transcript)|interpro:IPR025451|mint:Q2KHR3 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:vDgZ99Lo5fIvl2ef739OtWP/QLQ9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q5BKZ1 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-2560158|uniprotkb:Q6NSA2|uniprotkb:B4DLN0|uniprotkb:Q7Z638|uniprotkb:Q7Z6C2|uniprotkb:Q5VW97|uniprotkb:Q5VW96|uniprotkb:Q5VW94|uniprotkb:Q5VW93|ensembl:ENSP00000340796|uniprotkb:A8MYX1|uniprotkb:B4E179 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:zn326_human(display_long)|uniprotkb:ZNF326(gene name)|psi-mi:ZNF326(display_short)|uniprotkb:ZIRD(gene name synonym)|uniprotkb:Zinc finger protein 326(gene name synonym)|uniprotkb:Zinc finger protein interacting with mRNPs and DBC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_892020.1|refseq:NP_892021.1|refseq:XP_011539592.1|ensembl:ENSG00000162664(gene)|ensembl:ENST00000340281(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044609"(DBIRD complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q5BKZ1|refseq:XP_005270836.1|refseq:NP_001307114.1|refseq:NP_861446.2 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:y4ZeI0cWMpNA2nQN/hDk6Zn7XRA9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q03111 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-1384215|uniprotkb:Q14768|ensembl:ENSP00000252674 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:enl_human(display_long)|uniprotkb:MLLT1(gene name)|psi-mi:MLLT1(display_short)|uniprotkb:ENL(gene name synonym)|uniprotkb:LTG19(gene name synonym)|uniprotkb:YEATS1(gene name synonym)|uniprotkb:YEATS domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_005925.2|ensembl:ENSG00000130382(gene)|ensembl:ENST00000252674(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008023"(transcription elongation factor complex)|interpro:IPR005033(YEATS)|interpro:IPR038704|interpro:IPR040930|rcsb pdb:5J9S|rcsb pdb:6HPW|rcsb pdb:6HPX|rcsb pdb:6HPY|rcsb pdb:6HPZ|rcsb pdb:6HQ0|rcsb pdb:6HT0|rcsb pdb:6HT1|rcsb pdb:6T1I|rcsb pdb:6T1J|rcsb pdb:6T1L|rcsb pdb:6T1M|rcsb pdb:6T1N|rcsb pdb:6T1O|rcsb pdb:7B0T|rcsb pdb:7B10|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:H+j5XCIlsBwjsia+gMfTFKev3mA9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q06587 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q99496 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q8N163 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q8IY57 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q09028 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q96I24 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-954200|ensembl:ENSP00000318177|uniprotkb:Q92946|uniprotkb:Q9BVB6|intact:EBI-1760333|intact:EBI-1965411|uniprotkb:A3KFL0|uniprotkb:A3KFK8 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:fubp3_human(display_long)|uniprotkb:FUBP3(gene name)|psi-mi:FUBP3(display_short)|uniprotkb:FBP3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N ensembl:ENSG00000107164(gene)|ensembl:ENST00000319725(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q96I24|refseq:NP_003925.1|dip:DIP-50124N - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:xdCa+teqFaSxKNTpCJWQ5gcd0sQ9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q12948 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-1175253|uniprotkb:Q86UP7|uniprotkb:Q9BYM1|uniprotkb:Q9NUE5|uniprotkb:Q9UDD0|uniprotkb:Q9UP06|ensembl:ENSP00000493906 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:foxc1_human(display_long)|uniprotkb:Forkhead-related protein FKHL7(gene name synonym)|uniprotkb:Forkhead-related transcription factor 3(gene name synonym)|uniprotkb:FOXC1(gene name)|psi-mi:FOXC1(display_short)|uniprotkb:FKHL7(gene name synonym)|uniprotkb:FREAC3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N ensembl:ENST00000645831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001654"(eye development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|ensembl:ENSG00000054598(gene)|go:"GO:0001822"(kidney development)|go:"GO:0001945"(lymph vessel development)|go:"GO:0001958"(endochondral ossification)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0001756"(somitogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0021549"(cerebellum development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030203"(glycosaminoglycan metabolic process)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0008301"(DNA binding, bending)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:0060038"(cardiac muscle cell proliferation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR033067|go:"GO:0070098"(chemokine-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|mint:Q12948|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072010"(glomerular epithelium development)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1901491"(negative regulation of lymphangiogenesis)|go:"GO:1901534"(positive regulation of hematopoietic progenitor cell differentiation)|go:"GO:1902038"(positive regulation of hematopoietic stem cell differentiation)|go:"GO:1902257"(negative regulation of apoptotic process involved in outflow tract morphogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|ensembl:ENSP00000493906|refseq:NP_001444.2 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:+HuKwX8xMx86iCQW/a+vy/rWP389606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q9Y2X9 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-396200|uniprotkb:Q9NY92|uniprotkb:A6NF48|uniprotkb:B3KMX2|uniprotkb:Q5RKW5|intact:EBI-11018373|ensembl:ENSP00000294740|ensembl:ENSP00000356322 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:zn281_human(display_long)|uniprotkb:ZNF281(gene name)|psi-mi:ZNF281(display_short)|uniprotkb:GZP1(gene name synonym)|uniprotkb:ZBP99(gene name synonym)|uniprotkb:Zinc finger DNA-binding protein 99(gene name synonym)|uniprotkb:Transcription factor ZBP-99(gene name synonym)|uniprotkb:GC-box-binding zinc finger protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_036614.1|refseq:NP_001268222.1|refseq:NP_001268223.1|refseq:XP_016856376.1|refseq:XP_016856377.1|ensembl:ENSG00000162702(gene)|ensembl:ENST00000294740(transcript)|ensembl:ENST00000367353(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Y2X9 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:bjmz9ne6FkC0kbJUv13u8IoDYHM9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q9C005 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q9H000 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-2341005|uniprotkb:A6NIA2|uniprotkb:Q9BUY2|uniprotkb:B3KRC5|uniprotkb:Q96BD4|uniprotkb:Q8N391|uniprotkb:Q9NRY1|uniprotkb:B4DPR4|intact:EBI-11126681|ensembl:ENSP00000170447|ensembl:ENSP00000502893 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:mkrn2_human(display_long)|uniprotkb:MKRN2(gene name)|psi-mi:MKRN2(display_short)|uniprotkb:RNF62(gene name synonym)|uniprotkb:RING finger protein 62(gene name synonym)|uniprotkb:HSPC070(orf name)|uniprotkb:RING-type E3 ubiquitin transferase makorin-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_054879.3|refseq:NP_001258636.1|ensembl:ENSG00000075975(gene)|ensembl:ENST00000170447(transcript)|ensembl:ENST00000677816(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026293|interpro:IPR036855|interpro:IPR041367|mint:Q9H000 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:ZI7Jr4Fd52sQnfeNXXcZ0NscyD89606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q4VCS5 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:O00257 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:O00567 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q8IX01 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-949116|ensembl:ENSP00000337926|ensembl:ENSP00000389380|ensembl:ENSP00000472286|uniprotkb:O15071|uniprotkb:O60369|uniprotkb:Q5JPH7|uniprotkb:Q8WUF7|uniprotkb:C9JI71 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:sugp2_human(display_long)|uniprotkb:Arginine/serine-rich-splicing factor 14(gene name synonym)|uniprotkb:SUGP2(gene name)|psi-mi:SUGP2(display_short)|uniprotkb:KIAA0365(gene name synonym)|uniprotkb:SFRS14(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N ensembl:ENSG00000064607(gene)|ensembl:ENST00000337018(transcript)|ensembl:ENST00000452918(transcript)|ensembl:ENST00000601879(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000467(D111/G-patch)|interpro:IPR035967|interpro:IPR040169|mint:Q8IX01|rcsb pdb:1X4P|refseq:NP_001017392.2|refseq:NP_055699.2|refseq:XP_016881626.1|refseq:NP_001308626.1 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:hN1zWaoMMufKCQNO9VQ8NPiN0hI9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q8N488 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:P52597 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:Q9BSM1 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:P42568 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-716132|uniprotkb:B1AMQ2|uniprotkb:D3DRJ8|intact:EBI-11060385|ensembl:ENSP00000369695|intact:EBI-749963|uniprotkb:B2R7B3|uniprotkb:B7Z755|uniprotkb:Q8IVB0 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:af9_human(display_long)|uniprotkb:ALL1-fused gene from chromosome 9 protein(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein(gene name synonym)|uniprotkb:YEATS domain-containing protein 3(gene name synonym)|uniprotkb:MLLT3(gene name)|psi-mi:MLLT3(display_short)|uniprotkb:AF9(gene name synonym)|uniprotkb:YEATS3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_004520.2|refseq:NP_001273620.1|ensembl:ENSG00000171843(gene)|ensembl:ENST00000380338(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007379"(segment specification)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010467"(gene expression)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR005033(YEATS)|interpro:IPR038704|interpro:IPR040930|mint:P42568|rcsb pdb:2LM0|rcsb pdb:2MV7|rcsb pdb:2N4Q|rcsb pdb:2NDF|rcsb pdb:2NDG|rcsb pdb:4TMP|rcsb pdb:5HJB|rcsb pdb:5HJD|rcsb pdb:5YYF|rcsb pdb:6B7G|rcsb pdb:6L5Z|rcsb pdb:6LS6|rcsb pdb:6MIL|rcsb pdb:6MIM|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|dip:DIP-56409N - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:Z+g2iDUI+CzIrL7bMjY11hYKywQ9606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6W2J9 uniprotkb:P63208 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553433|imex:IM-25601-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - - figure legend:Table S2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2016/10/03 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:fJpdrbGaKCAvnJgOB1Fcs0BC3do false tag:n-n|ha tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q8NHM5 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q6W2J9 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q01804 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-1054396|uniprotkb:Q147U2|uniprotkb:Q1ZYK1|uniprotkb:Q6PG39|uniprotkb:Q96MQ5|uniprotkb:Q9NT94|uniprotkb:Q9UPV6|uniprotkb:B4DYS4|ensembl:ENSP00000395487 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:otud4_human(display_long)|uniprotkb:HIN-1(gene name synonym)|uniprotkb:HIV-1-induced protein HIN-1(gene name synonym)|uniprotkb:OTUD4(gene name)|psi-mi:OTUD4(display_short)|uniprotkb:KIAA1046(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:XP_005263136.1|refseq:NP_001096123.1|refseq:NP_059963.1|ensembl:ENSG00000164164(gene)|ensembl:ENST00000447906(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1903093"(regulation of protein K48-linked deubiquitination)|go:"GO:2000660"(negative regulation of interleukin-1-mediated signaling pathway)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR038765 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:humMGfho0HKWE4zhO7+G00gIJfc9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:P49750 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-712871|ensembl:ENSP00000324463|uniprotkb:P49752|uniprotkb:Q96I64|uniprotkb:Q9P1V7 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:ylpm1_human(display_long)|uniprotkb:Nuclear protein ZAP3(gene name synonym)|uniprotkb:ZAP113(gene name synonym)|uniprotkb:YLPM1(gene name)|psi-mi:YLPM1(display_short)|uniprotkb:C14orf170(gene name synonym)|uniprotkb:ZAP3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 ensembl:ENSG00000119596(gene)|ensembl:ENST00000325680(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0032204"(regulation of telomere maintenance)|interpro:IPR026314|interpro:IPR027417|refseq:NP_062535.2|ensembl:ENSP00000324463|dip:DIP-53676N - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:3w+7odPC5D2UQYimwmCgTBbvWR49606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q8TE76 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-3940432|uniprotkb:Q5JUK7|uniprotkb:Q96MZ2|uniprotkb:Q9HAI7|intact:EBI-28969055|ensembl:ENSP00000347821|uniprotkb:A1YR23|uniprotkb:A1YR24|uniprotkb:H7BXF1 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:morc4_human(display_long)|uniprotkb:MORC4(gene name)|psi-mi:MORC4(display_short)|uniprotkb:ZCWCC2(gene name synonym)|uniprotkb:Zinc finger CW-type coiled-coil domain protein 2(gene name synonym)|uniprotkb:ZCW4(gene name synonym)|uniprotkb:Zinc finger CW-type domain protein 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 ensembl:ENST00000255495|ensembl:ENSP00000255495|ensembl:ENSP00000347821|ensembl:ENSG00000133131(gene)|ensembl:ENST00000355610(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|interpro:IPR011124(Zinc finger, CW-type)|interpro:IPR036890|interpro:IPR041006|mint:Q8TE76|rcsb pdb:7K7T|refseq:NP_078933.3|refseq:NP_001078823.1 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:4ZXYEyXqgZ18LMwuAgPTsqRtPgw9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q5H9F3 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-8833946|uniprotkb:Q5H9F4|uniprotkb:Q9Y528|uniprotkb:Q8TEN3|uniprotkb:B5MDQ8|uniprotkb:Q6ZVE0|uniprotkb:Q5H9F2|ensembl:ENSP00000218147|ensembl:ENSP00000437775 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:bcorl_human(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 ensembl:ENSP00000218147|ensembl:ENSP00000437775|refseq:NP_068765.3|dip:DIP-60148N|ensembl:ENSG00000085185(gene)|ensembl:ENST00000218147(transcript)|ensembl:ENST00000540052(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q5H9F3|rcsb pdb:4HPM|rcsb pdb:5JH5 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q86VM9 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-1045965|uniprotkb:Q96DG4|uniprotkb:Q96MP7|ensembl:ENSP00000301011 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:zch18_human(display_long)|uniprotkb:NHN1(gene name synonym)|uniprotkb:Nuclear protein NHN1(gene name synonym)|uniprotkb:ZC3H18(gene name)|psi-mi:ZC3H18(display_short) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_001281269.1|ensembl:ENST00000301011(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0050779"(RNA destabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR041367|mint:Q86VM9|ensembl:ENSG00000158545(gene)|ensembl:ENSP00000301011|refseq:NP_653205.3 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:H9lST8OLyCpyi5AWYqFYskL0ezI9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:O00567 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q9HC52 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q9UQR1 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-2688184|uniprotkb:Q58EY5|uniprotkb:O43591|uniprotkb:O00389|uniprotkb:D3DN27|ensembl:ENSP00000420448|ensembl:ENSP00000353863|ensembl:ENSP00000419322|ensembl:ENSP00000420335|uniprotkb:Q6PJ98 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:zn148_human(display_long)|uniprotkb:ZBP89(gene name synonym)|uniprotkb:Transcription factor ZBP-89(gene name synonym)|uniprotkb:Zinc finger DNA-binding protein 89(gene name synonym)|uniprotkb:ZNF148(gene name)|psi-mi:ZNF148(display_short) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_068799.2|ensembl:ENST00000360647(transcript)|ensembl:ENST00000484491(transcript)|ensembl:ENST00000485866(transcript)|ensembl:ENST00000492394(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006968"(cellular defense response)|go:"GO:0007276"(gamete generation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0021762"(substantia nigra development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9UQR1|ensembl:ENSG00000163848(gene)|refseq:NP_001335353.1|refseq:NP_001335354.1|refseq:NP_001335355.1|refseq:NP_001335356.1|refseq:NP_001335357.1|refseq:NP_001335358.1|refseq:NP_001335359.1|refseq:NP_001335360.1|refseq:NP_001335361.1|refseq:NP_001335362.1|ensembl:ENSP00000353863|ensembl:ENSP00000420335|ensembl:ENSP00000420448|ensembl:ENSP00000419322 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:2H8lAaonZqAnCWDtUN8q55+03h49606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q2KHR3 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-11048246|uniprotkb:Q6ZUR5|uniprotkb:Q6ZU30|ensembl:ENSP00000382241 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:qser1_human(display_long)|uniprotkb:QSER1(gene name)|psi-mi:QSER1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_001070254.1|ensembl:ENSG00000060749(gene)|ensembl:ENST00000399302(transcript)|interpro:IPR025451|mint:Q2KHR3 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:vDgZ99Lo5fIvl2ef739OtWP/QLQ9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q5BKZ1 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-2560158|uniprotkb:Q6NSA2|uniprotkb:B4DLN0|uniprotkb:Q7Z638|uniprotkb:Q7Z6C2|uniprotkb:Q5VW97|uniprotkb:Q5VW96|uniprotkb:Q5VW94|uniprotkb:Q5VW93|ensembl:ENSP00000340796|uniprotkb:A8MYX1|uniprotkb:B4E179 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:zn326_human(display_long)|uniprotkb:ZNF326(gene name)|psi-mi:ZNF326(display_short)|uniprotkb:ZIRD(gene name synonym)|uniprotkb:Zinc finger protein 326(gene name synonym)|uniprotkb:Zinc finger protein interacting with mRNPs and DBC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_892020.1|refseq:NP_892021.1|refseq:XP_011539592.1|ensembl:ENSG00000162664(gene)|ensembl:ENST00000340281(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044609"(DBIRD complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q5BKZ1|refseq:XP_005270836.1|refseq:NP_001307114.1|refseq:NP_861446.2 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:y4ZeI0cWMpNA2nQN/hDk6Zn7XRA9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q03111 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-1384215|uniprotkb:Q14768|ensembl:ENSP00000252674 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:enl_human(display_long)|uniprotkb:MLLT1(gene name)|psi-mi:MLLT1(display_short)|uniprotkb:ENL(gene name synonym)|uniprotkb:LTG19(gene name synonym)|uniprotkb:YEATS1(gene name synonym)|uniprotkb:YEATS domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_005925.2|ensembl:ENSG00000130382(gene)|ensembl:ENST00000252674(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008023"(transcription elongation factor complex)|interpro:IPR005033(YEATS)|interpro:IPR038704|interpro:IPR040930|rcsb pdb:5J9S|rcsb pdb:6HPW|rcsb pdb:6HPX|rcsb pdb:6HPY|rcsb pdb:6HPZ|rcsb pdb:6HQ0|rcsb pdb:6HT0|rcsb pdb:6HT1|rcsb pdb:6T1I|rcsb pdb:6T1J|rcsb pdb:6T1L|rcsb pdb:6T1M|rcsb pdb:6T1N|rcsb pdb:6T1O|rcsb pdb:7B0T|rcsb pdb:7B10|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:H+j5XCIlsBwjsia+gMfTFKev3mA9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q06587 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q99496 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q8IY57 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:O00257 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q8N488 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:P52597 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:P42568 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-716132|uniprotkb:B1AMQ2|uniprotkb:D3DRJ8|intact:EBI-11060385|ensembl:ENSP00000369695|intact:EBI-749963|uniprotkb:B2R7B3|uniprotkb:B7Z755|uniprotkb:Q8IVB0 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:af9_human(display_long)|uniprotkb:ALL1-fused gene from chromosome 9 protein(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein(gene name synonym)|uniprotkb:YEATS domain-containing protein 3(gene name synonym)|uniprotkb:MLLT3(gene name)|psi-mi:MLLT3(display_short)|uniprotkb:AF9(gene name synonym)|uniprotkb:YEATS3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_004520.2|refseq:NP_001273620.1|ensembl:ENSG00000171843(gene)|ensembl:ENST00000380338(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007379"(segment specification)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010467"(gene expression)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR005033(YEATS)|interpro:IPR038704|interpro:IPR040930|mint:P42568|rcsb pdb:2LM0|rcsb pdb:2MV7|rcsb pdb:2N4Q|rcsb pdb:2NDF|rcsb pdb:2NDG|rcsb pdb:4TMP|rcsb pdb:5HJB|rcsb pdb:5HJD|rcsb pdb:5YYF|rcsb pdb:6B7G|rcsb pdb:6L5Z|rcsb pdb:6LS6|rcsb pdb:6MIL|rcsb pdb:6MIM|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|dip:DIP-56409N - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:Z+g2iDUI+CzIrL7bMjY11hYKywQ9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:P63208 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q7L576 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-1048143|uniprotkb:Q14467|uniprotkb:Q5IED0|uniprotkb:Q6ZSX1|uniprotkb:Q9BSD9|uniprotkb:Q9BVC7|uniprotkb:A8K6D9|ensembl:ENSP00000478779|ensembl:ENSP00000481038|ensembl:ENSP00000499947|ensembl:ENSP00000500331 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:cyfp1_human(display_long)|uniprotkb:Specifically Rac1-associated protein 1(gene name synonym)|uniprotkb:p140sra-1(gene name synonym)|uniprotkb:CYFIP1(gene name)|psi-mi:CYFIP1(display_short)|uniprotkb:KIAA0068(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_001028200.1|refseq:NP_055423.1|refseq:NP_001274739.1|ensembl:ENSG00000273749(gene)|ensembl:ENSG00000288461(gene)|ensembl:ENST00000610365(transcript)|ensembl:ENST00000617928(transcript)|ensembl:ENST00000671714(transcript)|ensembl:ENST00000672091(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0006417"(regulation of translation)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031209"(SCAR complex)|go:"GO:0005576"(extracellular region)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032433"(filopodium tip)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0005829"(cytosol)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050890"(cognition)|go:"GO:0051015"(actin filament binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060076"(excitatory synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090724"(central region of growth cone)|go:"GO:0090725"(peripheral region of growth cone)|go:"GO:0097484"(dendrite extension)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1903422"(negative regulation of synaptic vesicle recycling)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|mint:Q7L576|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001311049.1|refseq:NP_001311052.1|dip:DIP-38873N - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:cEF+RA9JRXz8Mbsl/s89Up2ONRc9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:Q9NVD3 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-11154084|ensembl:ENSP00000329189|ensembl:ENSP00000382163|uniprotkb:Q8NE19|uniprotkb:D3DSG4|uniprotkb:D3DSG2|uniprotkb:Q9BU46|uniprotkb:B4DT14 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:setd4_human(display_long)|uniprotkb:SETD4(gene name)|psi-mi:SETD4(display_short)|uniprotkb:C21orf18(gene name synonym)|uniprotkb:C21orf27(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_001007260.1|refseq:NP_001007262.1|refseq:NP_001273681.1|refseq:NP_059134.1|refseq:XP_011527938.1|refseq:XP_011527939.1|refseq:XP_011527940.1|refseq:XP_011527941.1|refseq:XP_011527942.1|refseq:XP_011527944.1|refseq:XP_011527945.1|refseq:XP_011527946.1|ensembl:ENSG00000185917(gene)|ensembl:ENST00000332131(transcript)|ensembl:ENST00000399215(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018023"(peptidyl-lysine trimethylation)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071863"(regulation of cell proliferation in bone marrow)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR015353(Rubisco LSMT substrate-binding)|interpro:IPR036464|interpro:IPR044429|mint:Q9NVD3|interpro:IPR016852(Lysine methylase, YDR198C, predicted)|refseq:XP_016883892.1|refseq:XP_016883893.1|refseq:XP_016883894.1 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:kRLpz0/bF71oDgTln5Gg7pArmQg9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:O75027 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-1236950|uniprotkb:O75345|uniprotkb:Q5VWY7|uniprotkb:Q5VWY8|uniprotkb:Q9BRE1|uniprotkb:Q9UND1|uniprotkb:Q9UP01|uniprotkb:G3XAC4|ensembl:ENSP00000362492 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:abcb7_human(display_long)|uniprotkb:ABCB7(gene name)|psi-mi:ABCB7(display_short)|uniprotkb:ABC7(gene name synonym)|uniprotkb:ATP-binding cassette transporter 7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 7, mitochondrial(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_001258626.1|ensembl:ENSG00000131269(gene)|ensembl:ENST00000373394(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070455"(positive regulation of heme biosynthetic process)|go:"GO:0140466"(iron-sulfur cluster export from the mitochondrion)|go:"GO:0140481"(ABC-type iron-sulfur cluster transporter activity)|go:"GO:1903331"(positive regulation of iron-sulfur cluster assembly)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:O75027|reactome:R-HSA-1369007|reactome:R-HSA-2564830|refseq:NP_004290.2|refseq:NP_001258625.1 - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:nsOzSS/enZTkOfd1nRlk8Wv4KRM9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BSM1 uniprotkb:P49711 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:"MI:0676"(tandem affinity purification) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12553841|imex:IM-25601-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) - - - figure legend:Table S3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/19 2018/04/06 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rigid:25y1fICyL6Srqql1LsYa9WQTg18 false tag:?-?|flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9HC52 uniprotkb:Q6W2J9 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12555423|imex:IM-25601-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:Supp 6B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2016/08/19 2016/10/04 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rigid:kWxnlGL7vx1gQM35l7y8GCIQ5aM false flag tag:?-?|mutation disrupting interaction strength:375-375 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9HC52 uniprotkb:Q9BSM1 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Béguelin et al. (2016) imex:IM-25601|pubmed:27505670 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12555423|imex:IM-25601-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 - - - figure legend:Supp 6B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2016/08/19 2016/10/04 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:kWxnlGL7vx1gQM35l7y8GCIQ5aM false flag tag:?-?|mutation disrupting interaction strength:375-375 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)