#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P21524	uniprotkb:Q04964	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	intact:EBI-27834|uniprotkb:D6VZB6|ensemblfungi:YML058W	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:sml1_yeast(display_long)|uniprotkb:SML1(gene name)|psi-mi:SML1(display_short)|uniprotkb:YM9958.04(orf name)|uniprotkb:YML058W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Misko et al. (2016)	pubmed:27155231|imex:IM-25592	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-12598208|imex:IM-25592-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	sgd:S000004523|refseq:NP_013653.1|dip:DIP-2734N|mint:Q04964|ensemblfungi:YML058W(gene)|ensemblfungi:YML058W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0034613"(cellular protein localization)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)	-	crc64:56BE1B077916E419	crc64:02735C9178E431B2	figure legend:f2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/10	2016/11/16	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rogid:R/pTLMZy/Iwuk3c/6GR43P705qM559292	rigid:tqwiNx9x4SQARVmhHsHL7/l2i+A	false	-	-	2	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21524	uniprotkb:Q04964	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	intact:EBI-27834|uniprotkb:D6VZB6|ensemblfungi:YML058W	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:sml1_yeast(display_long)|uniprotkb:SML1(gene name)|psi-mi:SML1(display_short)|uniprotkb:YM9958.04(orf name)|uniprotkb:YML058W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Misko et al. (2016)	pubmed:27155231|imex:IM-25592	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-12598284|imex:IM-25592-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	sgd:S000004523|refseq:NP_013653.1|dip:DIP-2734N|mint:Q04964|ensemblfungi:YML058W(gene)|ensemblfungi:YML058W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0034613"(cellular protein localization)|go:"GO:1905117"(regulation of ribonucleoside-diphosphate reductase activity)|go:"GO:1990846"(ribonucleoside-diphosphate reductase inhibitor activity)	-	crc64:56BE1B077916E419	crc64:02735C9178E431B2	figure legend:f2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/10	2016/11/16	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rogid:R/pTLMZy/Iwuk3c/6GR43P705qM559292	rigid:tqwiNx9x4SQARVmhHsHL7/l2i+A	false	-	-	6	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21524	uniprotkb:P21524	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Misko et al. (2016)	pubmed:27155231|imex:IM-25592	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-12598288|imex:IM-25592-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	-	crc64:56BE1B077916E419	crc64:56BE1B077916E419	figure legend:f2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/10	2016/11/16	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rigid:ttZBX6bStUAFlhWtJ6zd4mQQ6/M	false	-	-	6	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)