#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q719H9 uniprotkb:Q719H9 intact:EBI-9027502|uniprotkb:A8K1F5|ensembl:ENSP00000314831|ensembl:ENSP00000384367|ensembl:ENSP00000408405|ensembl:ENSP00000464170 intact:EBI-9027502|uniprotkb:A8K1F5|ensembl:ENSP00000314831|ensembl:ENSP00000384367|ensembl:ENSP00000408405|ensembl:ENSP00000464170 psi-mi:kctd1_human(display_long)|uniprotkb:KCTD1(gene name)|psi-mi:KCTD1(display_short)|uniprotkb:C18orf5(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 1(gene name synonym) psi-mi:kctd1_human(display_long)|uniprotkb:KCTD1(gene name)|psi-mi:KCTD1(display_short)|uniprotkb:C18orf5(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552112|imex:IM-25577-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016881197.1|refseq:NP_001129677.1|refseq:NP_001136202.1|refseq:NP_001245150.1|refseq:NP_945342.1|ensembl:ENSG00000134504(gene)|ensembl:ENST00000317932(transcript)|ensembl:ENST00000408011(transcript)|ensembl:ENST00000417602(transcript)|ensembl:ENST00000579973(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q719H9|rcsb pdb:5BXB|rcsb pdb:5BXD|rcsb pdb:6S4L|reactome:R-HSA-8866904 refseq:XP_016881197.1|refseq:NP_001129677.1|refseq:NP_001136202.1|refseq:NP_001245150.1|refseq:NP_945342.1|ensembl:ENSG00000134504(gene)|ensembl:ENST00000317932(transcript)|ensembl:ENST00000408011(transcript)|ensembl:ENST00000417602(transcript)|ensembl:ENST00000579973(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q719H9|rcsb pdb:5BXB|rcsb pdb:5BXD|rcsb pdb:6S4L|reactome:R-HSA-8866904 - - - figure legend:f1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2016/09/30 rogid:mv4g8/+TuoNkCitdTYpsxJH52I09606 rogid:mv4g8/+TuoNkCitdTYpsxJH52I09606 rigid:HqqCl8W0YypgzvcxW7i0qQatLHE false binding-associated region:1-135 binding-associated region:1-135 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NXV2 uniprotkb:Q9NXV2 intact:EBI-1056857|uniprotkb:D3DU96|ensembl:ENSP00000301738 intact:EBI-1056857|uniprotkb:D3DU96|ensembl:ENSP00000301738 psi-mi:kctd5_human(display_long)|uniprotkb:KCTD5(gene name)|psi-mi:KCTD5(display_short) psi-mi:kctd5_human(display_long)|uniprotkb:KCTD5(gene name)|psi-mi:KCTD5(display_short) psi-mi:"MI:0071"(molecular sieving) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552159|imex:IM-25577-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061865.1|interpro:IPR011333(BTB/POZ fold)|mint:Q9NXV2|rcsb pdb:3DRX|rcsb pdb:3DRY|rcsb pdb:3DRZ|ensembl:ENSG00000167977(gene)|ensembl:ENST00000301738(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation) refseq:NP_061865.1|interpro:IPR011333(BTB/POZ fold)|mint:Q9NXV2|rcsb pdb:3DRX|rcsb pdb:3DRY|rcsb pdb:3DRZ|ensembl:ENSG00000167977(gene)|ensembl:ENST00000301738(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation) - - - figure legend:f1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2016/09/30 rogid:KzXA4jgTKUY/EE1ORX+nMLCPfro9606 rogid:KzXA4jgTKUY/EE1ORX+nMLCPfro9606 rigid:MZ04kwcYWT9V6V/yABR/zUkdIkA false binding-associated region:44-145 binding-associated region:44-145 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NC69 uniprotkb:Q8NC69 intact:EBI-2511344|ensembl:ENSP00000347188|ensembl:ENSP00000384948|ensembl:ENSP00000417490|uniprotkb:Q8NBS6|uniprotkb:Q8TCA6|uniprotkb:B3KNI5 intact:EBI-2511344|ensembl:ENSP00000347188|ensembl:ENSP00000384948|ensembl:ENSP00000417490|uniprotkb:Q8NBS6|uniprotkb:Q8TCA6|uniprotkb:B3KNI5 psi-mi:kctd6_human(display_long)|uniprotkb:KCTD6(gene name)|psi-mi:KCTD6(display_short)|uniprotkb:KCASH3 protein(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 6(gene name synonym) psi-mi:kctd6_human(display_long)|uniprotkb:KCTD6(gene name)|psi-mi:KCTD6(display_short)|uniprotkb:KCASH3 protein(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 6(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552167|imex:IM-25577-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011333(BTB/POZ fold)|reactome:R-HSA-8931987|reactome:R-HSA-8951664|reactome:R-HSA-9018519|reactome:R-HSA-983168|ensembl:ENSG00000168301(gene)|ensembl:ENST00000355076(transcript)|ensembl:ENST00000404589(transcript)|ensembl:ENST00000490264(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031430"(M band)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|refseq:NP_001121686.1|refseq:NP_699162.3|refseq:XP_005264994.1 interpro:IPR011333(BTB/POZ fold)|reactome:R-HSA-8931987|reactome:R-HSA-8951664|reactome:R-HSA-9018519|reactome:R-HSA-983168|ensembl:ENSG00000168301(gene)|ensembl:ENST00000355076(transcript)|ensembl:ENST00000404589(transcript)|ensembl:ENST00000490264(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031430"(M band)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|refseq:NP_001121686.1|refseq:NP_699162.3|refseq:XP_005264994.1 - - - figure legend:f1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2016/09/30 rogid:m2fVaYsVQ2wHfnYhxdgo1Q0J+TI9606 rogid:m2fVaYsVQ2wHfnYhxdgo1Q0J+TI9606 rigid:0BWaRRUiQNwd4O6cN2/Km0+aNjY false binding-associated region:10-110 binding-associated region:10-110 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q693B1 uniprotkb:Q693B1 intact:EBI-12552177|uniprotkb:B3KPE0|ensembl:ENSP00000495203|ensembl:ENSP00000500224 intact:EBI-12552177|uniprotkb:B3KPE0|ensembl:ENSP00000495203|ensembl:ENSP00000500224 psi-mi:kcd11_human(display_long)|uniprotkb:KCTD11(gene name)|psi-mi:KCTD11(display_short)|uniprotkb:C17orf36(gene name synonym)|uniprotkb:REN(gene name synonym)|uniprotkb:KCASH1 protein(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 11(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase subunit KCTD11(gene name synonym) psi-mi:kcd11_human(display_long)|uniprotkb:KCTD11(gene name)|psi-mi:KCTD11(display_short)|uniprotkb:C17orf36(gene name synonym)|uniprotkb:REN(gene name synonym)|uniprotkb:KCASH1 protein(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 11(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase subunit KCTD11(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552175|imex:IM-25577-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002914.1|ensembl:ENSG00000213859(gene)|ensembl:ENST00000576980(transcript)|ensembl:ENST00000672140(transcript)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000288399(gene) refseq:NP_001002914.1|ensembl:ENSG00000213859(gene)|ensembl:ENST00000576980(transcript)|ensembl:ENST00000672140(transcript)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000288399(gene) - - - figure legend:f1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2016/09/30 rogid:5eQkqUu7kVSse54hSMcKAAIR9AI9606 rogid:5eQkqUu7kVSse54hSMcKAAIR9AI9606 rigid:sXow1CN6LIjinhsK3O261Vit90w false binding-associated region:15-116 binding-associated region:15-116 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96CX2 uniprotkb:Q96CX2 intact:EBI-358358|ensembl:ENSP00000366694 intact:EBI-358358|ensembl:ENSP00000366694 psi-mi:kcd12_human(display_long)|uniprotkb:KCTD12(gene name)|psi-mi:KCTD12(display_short)|uniprotkb:C13orf2(gene name synonym)|uniprotkb:KIAA1778(gene name synonym)|uniprotkb:PFET1(gene name synonym)|uniprotkb:Pfetin(gene name synonym)|uniprotkb:Predominantly fetal expressed T1 domain(gene name synonym) psi-mi:kcd12_human(display_long)|uniprotkb:KCTD12(gene name)|psi-mi:KCTD12(display_short)|uniprotkb:C13orf2(gene name synonym)|uniprotkb:KIAA1778(gene name synonym)|uniprotkb:PFET1(gene name synonym)|uniprotkb:Pfetin(gene name synonym)|uniprotkb:Predominantly fetal expressed T1 domain(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552204|imex:IM-25577-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612453.1|ensembl:ENSG00000178695(gene)|ensembl:ENST00000377474(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q96CX2|rcsb pdb:6M8S|rcsb pdb:6QZL refseq:NP_612453.1|ensembl:ENSG00000178695(gene)|ensembl:ENST00000377474(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q96CX2|rcsb pdb:6M8S|rcsb pdb:6QZL - - - figure legend:f1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2016/09/30 rogid:Xxp3in+fgJzZXJaorHFWXTbyKKQ9606 rogid:Xxp3in+fgJzZXJaorHFWXTbyKKQ9606 rigid:5kadqqc2Gk4wfKcOFAwEoluCGaU false binding-associated region:27-131 binding-associated region:27-131 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96SI1 uniprotkb:Q96SI1 intact:EBI-715783|uniprotkb:Q9BVI6|uniprotkb:A8K600|ensembl:ENSP00000394390|ensembl:ENSP00000464812|ensembl:ENSP00000467612|ensembl:ENSP00000508199 intact:EBI-715783|uniprotkb:Q9BVI6|uniprotkb:A8K600|ensembl:ENSP00000394390|ensembl:ENSP00000464812|ensembl:ENSP00000467612|ensembl:ENSP00000508199 psi-mi:kcd15_human(display_long)|uniprotkb:KCTD15(gene name)|psi-mi:KCTD15(display_short)|uniprotkb:Potassium channel tetramerization domain-containing protein 15(gene name synonym) psi-mi:kcd15_human(display_long)|uniprotkb:KCTD15(gene name)|psi-mi:KCTD15(display_short)|uniprotkb:Potassium channel tetramerization domain-containing protein 15(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552213|imex:IM-25577-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123466.1|refseq:NP_001123467.1|refseq:NP_076981.2|ensembl:ENSG00000153885(gene)|ensembl:ENST00000430256(transcript)|ensembl:ENST00000588881(transcript)|ensembl:ENST00000589786(transcript)|ensembl:ENST00000683859(transcript)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|reactome:R-HSA-8866904|refseq:XP_011525599.1|refseq:XP_011525600.1|refseq:XP_016882772.1|refseq:XP_011525598.1 refseq:NP_001123466.1|refseq:NP_001123467.1|refseq:NP_076981.2|ensembl:ENSG00000153885(gene)|ensembl:ENST00000430256(transcript)|ensembl:ENST00000588881(transcript)|ensembl:ENST00000589786(transcript)|ensembl:ENST00000683859(transcript)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|reactome:R-HSA-8866904|refseq:XP_011525599.1|refseq:XP_011525600.1|refseq:XP_016882772.1|refseq:XP_011525598.1 - - - figure legend:f1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2016/09/30 rogid:diG+43SilvYzJJ0SCB3HY+ktJMQ9606 rogid:diG+43SilvYzJJ0SCB3HY+ktJMQ9606 rigid:gXgVEpecjZcEgLFC06wHcKB+5HQ false binding-associated region:61-157 binding-associated region:61-157 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WZ19 uniprotkb:Q8WZ19 intact:EBI-742916|ensembl:ENSP00000311202|ensembl:ENSP00000455785|uniprotkb:Q96P93|uniprotkb:Q96SA1|uniprotkb:A8K0R5 intact:EBI-742916|ensembl:ENSP00000311202|ensembl:ENSP00000455785|uniprotkb:Q96P93|uniprotkb:Q96SA1|uniprotkb:A8K0R5 psi-mi:bacd1_human(display_long)|uniprotkb:Polymerase delta-interacting protein 1(gene name synonym)|uniprotkb:TNFAIP1-like protein(gene name synonym)|uniprotkb:KCTD13(gene name)|psi-mi:KCTD13(display_short)|uniprotkb:PDIP1(gene name synonym)|uniprotkb:POLDIP1(gene name synonym)|uniprotkb:FKSG86(orf name)|uniprotkb:PP6832(orf name)|uniprotkb:BACURD1(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein KCTD13(gene name synonym) psi-mi:bacd1_human(display_long)|uniprotkb:Polymerase delta-interacting protein 1(gene name synonym)|uniprotkb:TNFAIP1-like protein(gene name synonym)|uniprotkb:KCTD13(gene name)|psi-mi:KCTD13(display_short)|uniprotkb:PDIP1(gene name synonym)|uniprotkb:POLDIP1(gene name synonym)|uniprotkb:FKSG86(orf name)|uniprotkb:PP6832(orf name)|uniprotkb:BACURD1(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein KCTD13(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552221|imex:IM-25577-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_849194.1|ensembl:ENSG00000174943(gene)|ensembl:ENST00000308768(transcript)|ensembl:ENST00000568000(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q8WZ19|rcsb pdb:4UIJ|reactome:R-HSA-9696264|reactome:R-HSA-9696270 refseq:NP_849194.1|ensembl:ENSG00000174943(gene)|ensembl:ENST00000308768(transcript)|ensembl:ENST00000568000(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q8WZ19|rcsb pdb:4UIJ|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:f1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2016/09/30 rogid:hAH5yJEoda0H1anmnSXWHO0o1ZM9606 rogid:hAH5yJEoda0H1anmnSXWHO0o1ZM9606 rigid:DWE1VEU05BZ8p/ZtZeT1Qfu5r+Y false binding-associated region:1-135 binding-associated region:1-135 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q693B1 uniprotkb:Q693B1 intact:EBI-12552177|uniprotkb:B3KPE0|ensembl:ENSP00000495203|ensembl:ENSP00000500224 intact:EBI-12552177|uniprotkb:B3KPE0|ensembl:ENSP00000495203|ensembl:ENSP00000500224 psi-mi:kcd11_human(display_long)|uniprotkb:KCTD11(gene name)|psi-mi:KCTD11(display_short)|uniprotkb:C17orf36(gene name synonym)|uniprotkb:REN(gene name synonym)|uniprotkb:KCASH1 protein(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 11(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase subunit KCTD11(gene name synonym) psi-mi:kcd11_human(display_long)|uniprotkb:KCTD11(gene name)|psi-mi:KCTD11(display_short)|uniprotkb:C17orf36(gene name synonym)|uniprotkb:REN(gene name synonym)|uniprotkb:KCASH1 protein(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 11(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase subunit KCTD11(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552237|imex:IM-25577-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002914.1|ensembl:ENSG00000213859(gene)|ensembl:ENST00000576980(transcript)|ensembl:ENST00000672140(transcript)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000288399(gene) refseq:NP_001002914.1|ensembl:ENSG00000213859(gene)|ensembl:ENST00000576980(transcript)|ensembl:ENST00000672140(transcript)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000288399(gene) - - - figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2016/09/30 rogid:5eQkqUu7kVSse54hSMcKAAIR9AI9606 rogid:5eQkqUu7kVSse54hSMcKAAIR9AI9606 rigid:YMfFEmlpdIgyPzKg3qhxLzSxaBQ false binding-associated region:15-116 binding-associated region:15-116 5 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96CX2 uniprotkb:Q96CX2 intact:EBI-358358|ensembl:ENSP00000366694 intact:EBI-358358|ensembl:ENSP00000366694 psi-mi:kcd12_human(display_long)|uniprotkb:KCTD12(gene name)|psi-mi:KCTD12(display_short)|uniprotkb:C13orf2(gene name synonym)|uniprotkb:KIAA1778(gene name synonym)|uniprotkb:PFET1(gene name synonym)|uniprotkb:Pfetin(gene name synonym)|uniprotkb:Predominantly fetal expressed T1 domain(gene name synonym) psi-mi:kcd12_human(display_long)|uniprotkb:KCTD12(gene name)|psi-mi:KCTD12(display_short)|uniprotkb:C13orf2(gene name synonym)|uniprotkb:KIAA1778(gene name synonym)|uniprotkb:PFET1(gene name synonym)|uniprotkb:Pfetin(gene name synonym)|uniprotkb:Predominantly fetal expressed T1 domain(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552253|imex:IM-25577-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612453.1|ensembl:ENSG00000178695(gene)|ensembl:ENST00000377474(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q96CX2|rcsb pdb:6M8S|rcsb pdb:6QZL refseq:NP_612453.1|ensembl:ENSG00000178695(gene)|ensembl:ENST00000377474(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q96CX2|rcsb pdb:6M8S|rcsb pdb:6QZL - - - figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2016/09/30 rogid:Xxp3in+fgJzZXJaorHFWXTbyKKQ9606 rogid:Xxp3in+fgJzZXJaorHFWXTbyKKQ9606 rigid:UHqYWbrH+8koX5hYKWJTqgjhyA8 false binding-associated region:27-131 binding-associated region:27-131 5 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96SI1 uniprotkb:Q96SI1 intact:EBI-715783|uniprotkb:Q9BVI6|uniprotkb:A8K600|ensembl:ENSP00000394390|ensembl:ENSP00000464812|ensembl:ENSP00000467612|ensembl:ENSP00000508199 intact:EBI-715783|uniprotkb:Q9BVI6|uniprotkb:A8K600|ensembl:ENSP00000394390|ensembl:ENSP00000464812|ensembl:ENSP00000467612|ensembl:ENSP00000508199 psi-mi:kcd15_human(display_long)|uniprotkb:KCTD15(gene name)|psi-mi:KCTD15(display_short)|uniprotkb:Potassium channel tetramerization domain-containing protein 15(gene name synonym) psi-mi:kcd15_human(display_long)|uniprotkb:KCTD15(gene name)|psi-mi:KCTD15(display_short)|uniprotkb:Potassium channel tetramerization domain-containing protein 15(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552262|imex:IM-25577-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123466.1|refseq:NP_001123467.1|refseq:NP_076981.2|ensembl:ENSG00000153885(gene)|ensembl:ENST00000430256(transcript)|ensembl:ENST00000588881(transcript)|ensembl:ENST00000589786(transcript)|ensembl:ENST00000683859(transcript)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|reactome:R-HSA-8866904|refseq:XP_011525599.1|refseq:XP_011525600.1|refseq:XP_016882772.1|refseq:XP_011525598.1 refseq:NP_001123466.1|refseq:NP_001123467.1|refseq:NP_076981.2|ensembl:ENSG00000153885(gene)|ensembl:ENST00000430256(transcript)|ensembl:ENST00000588881(transcript)|ensembl:ENST00000589786(transcript)|ensembl:ENST00000683859(transcript)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|reactome:R-HSA-8866904|refseq:XP_011525599.1|refseq:XP_011525600.1|refseq:XP_016882772.1|refseq:XP_011525598.1 - - - figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2016/09/30 rogid:diG+43SilvYzJJ0SCB3HY+ktJMQ9606 rogid:diG+43SilvYzJJ0SCB3HY+ktJMQ9606 rigid:D4P4lxWQYRQwW4rLHh030NLwF2I false binding-associated region:61-157 binding-associated region:61-157 5 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WZ19 uniprotkb:Q8WZ19 intact:EBI-742916|ensembl:ENSP00000311202|ensembl:ENSP00000455785|uniprotkb:Q96P93|uniprotkb:Q96SA1|uniprotkb:A8K0R5 intact:EBI-742916|ensembl:ENSP00000311202|ensembl:ENSP00000455785|uniprotkb:Q96P93|uniprotkb:Q96SA1|uniprotkb:A8K0R5 psi-mi:bacd1_human(display_long)|uniprotkb:Polymerase delta-interacting protein 1(gene name synonym)|uniprotkb:TNFAIP1-like protein(gene name synonym)|uniprotkb:KCTD13(gene name)|psi-mi:KCTD13(display_short)|uniprotkb:PDIP1(gene name synonym)|uniprotkb:POLDIP1(gene name synonym)|uniprotkb:FKSG86(orf name)|uniprotkb:PP6832(orf name)|uniprotkb:BACURD1(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein KCTD13(gene name synonym) psi-mi:bacd1_human(display_long)|uniprotkb:Polymerase delta-interacting protein 1(gene name synonym)|uniprotkb:TNFAIP1-like protein(gene name synonym)|uniprotkb:KCTD13(gene name)|psi-mi:KCTD13(display_short)|uniprotkb:PDIP1(gene name synonym)|uniprotkb:POLDIP1(gene name synonym)|uniprotkb:FKSG86(orf name)|uniprotkb:PP6832(orf name)|uniprotkb:BACURD1(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein KCTD13(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552273|imex:IM-25577-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_849194.1|ensembl:ENSG00000174943(gene)|ensembl:ENST00000308768(transcript)|ensembl:ENST00000568000(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q8WZ19|rcsb pdb:4UIJ|reactome:R-HSA-9696264|reactome:R-HSA-9696270 refseq:NP_849194.1|ensembl:ENSG00000174943(gene)|ensembl:ENST00000308768(transcript)|ensembl:ENST00000568000(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q8WZ19|rcsb pdb:4UIJ|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2016/09/30 rogid:hAH5yJEoda0H1anmnSXWHO0o1ZM9606 rogid:hAH5yJEoda0H1anmnSXWHO0o1ZM9606 rigid:HKt2pSnqoXIzxiYXFk5j9J8mZWQ false binding-associated region:1-135 binding-associated region:1-135 5 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q719H9 uniprotkb:Q719H9 intact:EBI-9027502|uniprotkb:A8K1F5|ensembl:ENSP00000314831|ensembl:ENSP00000384367|ensembl:ENSP00000408405|ensembl:ENSP00000464170 intact:EBI-9027502|uniprotkb:A8K1F5|ensembl:ENSP00000314831|ensembl:ENSP00000384367|ensembl:ENSP00000408405|ensembl:ENSP00000464170 psi-mi:kctd1_human(display_long)|uniprotkb:KCTD1(gene name)|psi-mi:KCTD1(display_short)|uniprotkb:C18orf5(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 1(gene name synonym) psi-mi:kctd1_human(display_long)|uniprotkb:KCTD1(gene name)|psi-mi:KCTD1(display_short)|uniprotkb:C18orf5(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 1(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552281|imex:IM-25577-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016881197.1|refseq:NP_001129677.1|refseq:NP_001136202.1|refseq:NP_001245150.1|refseq:NP_945342.1|ensembl:ENSG00000134504(gene)|ensembl:ENST00000317932(transcript)|ensembl:ENST00000408011(transcript)|ensembl:ENST00000417602(transcript)|ensembl:ENST00000579973(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q719H9|rcsb pdb:5BXB|rcsb pdb:5BXD|rcsb pdb:6S4L|reactome:R-HSA-8866904 refseq:XP_016881197.1|refseq:NP_001129677.1|refseq:NP_001136202.1|refseq:NP_001245150.1|refseq:NP_945342.1|ensembl:ENSG00000134504(gene)|ensembl:ENST00000317932(transcript)|ensembl:ENST00000408011(transcript)|ensembl:ENST00000417602(transcript)|ensembl:ENST00000579973(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q719H9|rcsb pdb:5BXB|rcsb pdb:5BXD|rcsb pdb:6S4L|reactome:R-HSA-8866904 - - - figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2016/09/30 rogid:mv4g8/+TuoNkCitdTYpsxJH52I09606 rogid:mv4g8/+TuoNkCitdTYpsxJH52I09606 rigid:fdJ+QqUnDj0TIU4XQB9lmyONrgk false binding-associated region:1-135 binding-associated region:1-135 5 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NXV2 uniprotkb:Q9NXV2 intact:EBI-1056857|uniprotkb:D3DU96|ensembl:ENSP00000301738 intact:EBI-1056857|uniprotkb:D3DU96|ensembl:ENSP00000301738 psi-mi:kctd5_human(display_long)|uniprotkb:KCTD5(gene name)|psi-mi:KCTD5(display_short) psi-mi:kctd5_human(display_long)|uniprotkb:KCTD5(gene name)|psi-mi:KCTD5(display_short) psi-mi:"MI:0040"(electron microscopy) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552289|imex:IM-25577-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061865.1|interpro:IPR011333(BTB/POZ fold)|mint:Q9NXV2|rcsb pdb:3DRX|rcsb pdb:3DRY|rcsb pdb:3DRZ|ensembl:ENSG00000167977(gene)|ensembl:ENST00000301738(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation) refseq:NP_061865.1|interpro:IPR011333(BTB/POZ fold)|mint:Q9NXV2|rcsb pdb:3DRX|rcsb pdb:3DRY|rcsb pdb:3DRZ|ensembl:ENSG00000167977(gene)|ensembl:ENST00000301738(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation) - - - figure legend:f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2016/09/30 rogid:KzXA4jgTKUY/EE1ORX+nMLCPfro9606 rogid:KzXA4jgTKUY/EE1ORX+nMLCPfro9606 rigid:X+fhNemqHFapac8Gg9b22ttFzxU false binding-associated region:44-145 binding-associated region:44-145 5 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NC69 uniprotkb:Q8NC69 intact:EBI-2511344|ensembl:ENSP00000347188|ensembl:ENSP00000384948|ensembl:ENSP00000417490|uniprotkb:Q8NBS6|uniprotkb:Q8TCA6|uniprotkb:B3KNI5 intact:EBI-2511344|ensembl:ENSP00000347188|ensembl:ENSP00000384948|ensembl:ENSP00000417490|uniprotkb:Q8NBS6|uniprotkb:Q8TCA6|uniprotkb:B3KNI5 psi-mi:kctd6_human(display_long)|uniprotkb:KCTD6(gene name)|psi-mi:KCTD6(display_short)|uniprotkb:KCASH3 protein(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 6(gene name synonym) psi-mi:kctd6_human(display_long)|uniprotkb:KCTD6(gene name)|psi-mi:KCTD6(display_short)|uniprotkb:KCASH3 protein(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 6(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552297|imex:IM-25577-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011333(BTB/POZ fold)|reactome:R-HSA-8931987|reactome:R-HSA-8951664|reactome:R-HSA-9018519|reactome:R-HSA-983168|ensembl:ENSG00000168301(gene)|ensembl:ENST00000355076(transcript)|ensembl:ENST00000404589(transcript)|ensembl:ENST00000490264(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031430"(M band)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|refseq:NP_001121686.1|refseq:NP_699162.3|refseq:XP_005264994.1 interpro:IPR011333(BTB/POZ fold)|reactome:R-HSA-8931987|reactome:R-HSA-8951664|reactome:R-HSA-9018519|reactome:R-HSA-983168|ensembl:ENSG00000168301(gene)|ensembl:ENST00000355076(transcript)|ensembl:ENST00000404589(transcript)|ensembl:ENST00000490264(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031430"(M band)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|refseq:NP_001121686.1|refseq:NP_699162.3|refseq:XP_005264994.1 - - - figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2016/09/30 rogid:m2fVaYsVQ2wHfnYhxdgo1Q0J+TI9606 rogid:m2fVaYsVQ2wHfnYhxdgo1Q0J+TI9606 rigid:kY/BM+oCkkq9eNfqT3lCD4/VOlc false binding-associated region:10-110 binding-associated region:10-110 5 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13618 uniprotkb:Q8NC69 intact:EBI-456129|uniprotkb:O75415|uniprotkb:Q569L3|uniprotkb:Q9UBI8|uniprotkb:B8ZZC3|uniprotkb:Q9UET7|uniprotkb:A8K536|ensembl:ENSP00000264414 intact:EBI-2511344|ensembl:ENSP00000347188|ensembl:ENSP00000384948|ensembl:ENSP00000417490|uniprotkb:Q8NBS6|uniprotkb:Q8TCA6|uniprotkb:B3KNI5 psi-mi:cul3_human(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:KIAA0617(gene name synonym) psi-mi:kctd6_human(display_long)|uniprotkb:KCTD6(gene name)|psi-mi:KCTD6(display_short)|uniprotkb:KCASH3 protein(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 6(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Smaldone et al. (2016) imex:IM-25577|pubmed:27152988 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-12552309|imex:IM-25577-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003581.1|refseq:NP_001244126.1|refseq:NP_001244127.1|dip:DIP-31611N|ensembl:ENSG00000036257(gene)|ensembl:ENST00000264414(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000922"(spindle pole)|go:"GO:0001831"(trophectodermal cellular morphogenesis)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017145"(stem cell division)|go:"GO:0030030"(cell projection organization)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072576"(liver morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13618|rcsb pdb:2MYL|rcsb pdb:2MYM|rcsb pdb:4AP2|rcsb pdb:4APF|rcsb pdb:4EOZ|rcsb pdb:4HXI|rcsb pdb:5NLB|rcsb pdb:6I2M|reactome:R-HSA-4641258|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9706019|reactome:R-HSA-983168 interpro:IPR011333(BTB/POZ fold)|reactome:R-HSA-8931987|reactome:R-HSA-8951664|reactome:R-HSA-9018519|reactome:R-HSA-983168|ensembl:ENSG00000168301(gene)|ensembl:ENST00000355076(transcript)|ensembl:ENST00000404589(transcript)|ensembl:ENST00000490264(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031430"(M band)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|refseq:NP_001121686.1|refseq:NP_699162.3|refseq:XP_005264994.1 - - - figure legend:f4|comment:"These results confirm the pentameric nature of KCTD6BTB and, simultaneously, the 5 : 5 stoichiometry of the KCTD6BTB – Cul3NTD complex. A deep inspection of the micrographs (Fig. 4) unravels that distinct Cul3NTD molecules assume different orientations. This indicates that Cul3 is endowed with a remarkable flexibility in these complexes."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/30 2017/01/20 rogid:xI/8pHB9nckOW629STOqKba4KzQ9606 rogid:m2fVaYsVQ2wHfnYhxdgo1Q0J+TI9606 rigid:VbhWRuqdPoWAw8U/DI6WEd3X2Sg false binding-associated region:20-381 binding-associated region:10-110 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)