#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P42224	uniprotkb:Q4VW77	intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703	intact:EBI-11499224	psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym)	psi-mi:q4vw77_9alph(display_long)|uniprotkb:UL47(gene name)|psi-mi:UL47(display_short)|uniprotkb:AAADCAAH_00010(orf name)|uniprotkb:BLEONNCJ_00010(orf name)|uniprotkb:BLPDLEPH_00010(orf name)|uniprotkb:DCJDKEDG_00010(orf name)|uniprotkb:DILPLKIK_00010(orf name)|uniprotkb:DJCKHMNK_00010(orf name)|uniprotkb:NBBNDGNH_00010(orf name)|uniprotkb:NCKHNGOI_00010(orf name)|uniprotkb:NFOBEAPH_00010(orf name)|uniprotkb:OCMKPLLD_00010(orf name)|uniprotkb:OHMFJBFK_00010(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sharmin et al. (2016)	pubmed:26889034|imex:IM-25966	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10320(Bovine herpesvirus 1)|taxid:10320(Bovine herpesvirus 1)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-11896624|imex:IM-25966-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N	interpro:IPR005029(Herpesvirus UL47 protein)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0042025"(host cell nucleus)	-	-	-	figure legend:2A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/07/25	2016/08/10	rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606	rogid:Vu0N4WHtxZwh0AxlKrrZbB+Qge010320	rigid:el8ndJaPZrRpFObdo1aj0d7z6oo	false	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P42224	uniprotkb:Q4VW77	intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703	intact:EBI-11499224	psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym)	psi-mi:q4vw77_9alph(display_long)|uniprotkb:UL47(gene name)|psi-mi:UL47(display_short)|uniprotkb:AAADCAAH_00010(orf name)|uniprotkb:BLEONNCJ_00010(orf name)|uniprotkb:BLPDLEPH_00010(orf name)|uniprotkb:DCJDKEDG_00010(orf name)|uniprotkb:DILPLKIK_00010(orf name)|uniprotkb:DJCKHMNK_00010(orf name)|uniprotkb:NBBNDGNH_00010(orf name)|uniprotkb:NCKHNGOI_00010(orf name)|uniprotkb:NFOBEAPH_00010(orf name)|uniprotkb:OCMKPLLD_00010(orf name)|uniprotkb:OHMFJBFK_00010(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sharmin et al. (2016)	pubmed:26889034|imex:IM-25966	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10320(Bovine herpesvirus 1)|taxid:10320(Bovine herpesvirus 1)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-11896636|imex:IM-25966-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N	interpro:IPR005029(Herpesvirus UL47 protein)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0042025"(host cell nucleus)	-	-	-	figure legend:2B and 4|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/07/25	2016/07/25	rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606	rogid:Vu0N4WHtxZwh0AxlKrrZbB+Qge010320	rigid:el8ndJaPZrRpFObdo1aj0d7z6oo	false	-	flag tag:n-n|sufficient binding region:631-686|sufficient binding region:259-371|sufficient binding region:372-483	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:B0JYL6	uniprotkb:Q4VW77	intact:EBI-11896680|uniprotkb:F1MM76	intact:EBI-11499224	psi-mi:b0jyl6_bovin(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)	psi-mi:q4vw77_9alph(display_long)|uniprotkb:UL47(gene name)|psi-mi:UL47(display_short)|uniprotkb:AAADCAAH_00010(orf name)|uniprotkb:BLEONNCJ_00010(orf name)|uniprotkb:BLPDLEPH_00010(orf name)|uniprotkb:DCJDKEDG_00010(orf name)|uniprotkb:DILPLKIK_00010(orf name)|uniprotkb:DJCKHMNK_00010(orf name)|uniprotkb:NBBNDGNH_00010(orf name)|uniprotkb:NCKHNGOI_00010(orf name)|uniprotkb:NFOBEAPH_00010(orf name)|uniprotkb:OCMKPLLD_00010(orf name)|uniprotkb:OHMFJBFK_00010(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sharmin et al. (2016)	pubmed:26889034|imex:IM-25966	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:10320(Bovine herpesvirus 1)|taxid:10320(Bovine herpesvirus 1)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-11896658|imex:IM-25966-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR022752|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|interpro:IPR038295|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860	interpro:IPR005029(Herpesvirus UL47 protein)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0042025"(host cell nucleus)	-	-	-	figure legend:2D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9913(bovin-mdbk)|taxid:9913(Bos taurus)	-	2016/07/25	2016/07/25	rogid:aKUAQrvkbhJKI5tF5fTWNhwF7qA9913	rogid:Vu0N4WHtxZwh0AxlKrrZbB+Qge010320	rigid:8lnBV4FqoT7bzP9wfHHd3Ke1Uec	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:B0JYL6	uniprotkb:Q4VW77	intact:EBI-11896680|uniprotkb:F1MM76	intact:EBI-11499224	psi-mi:b0jyl6_bovin(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)	psi-mi:q4vw77_9alph(display_long)|uniprotkb:UL47(gene name)|psi-mi:UL47(display_short)|uniprotkb:AAADCAAH_00010(orf name)|uniprotkb:BLEONNCJ_00010(orf name)|uniprotkb:BLPDLEPH_00010(orf name)|uniprotkb:DCJDKEDG_00010(orf name)|uniprotkb:DILPLKIK_00010(orf name)|uniprotkb:DJCKHMNK_00010(orf name)|uniprotkb:NBBNDGNH_00010(orf name)|uniprotkb:NCKHNGOI_00010(orf name)|uniprotkb:NFOBEAPH_00010(orf name)|uniprotkb:OCMKPLLD_00010(orf name)|uniprotkb:OHMFJBFK_00010(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sharmin et al. (2016)	pubmed:26889034|imex:IM-25966	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:10320(Bovine herpesvirus 1)|taxid:10320(Bovine herpesvirus 1)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-11896733|imex:IM-25966-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR022752|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|interpro:IPR038295|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860	interpro:IPR005029(Herpesvirus UL47 protein)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0042025"(host cell nucleus)	-	-	-	figure legend:2E|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9913(bovin-mdbk)|taxid:9913(Bos taurus)	-	2016/07/25	2016/07/25	rogid:aKUAQrvkbhJKI5tF5fTWNhwF7qA9913	rogid:Vu0N4WHtxZwh0AxlKrrZbB+Qge010320	rigid:8lnBV4FqoT7bzP9wfHHd3Ke1Uec	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:B0JYL6	uniprotkb:Q4VW77	intact:EBI-11896680|uniprotkb:F1MM76	intact:EBI-11499224	psi-mi:b0jyl6_bovin(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)	psi-mi:q4vw77_9alph(display_long)|uniprotkb:UL47(gene name)|psi-mi:UL47(display_short)|uniprotkb:AAADCAAH_00010(orf name)|uniprotkb:BLEONNCJ_00010(orf name)|uniprotkb:BLPDLEPH_00010(orf name)|uniprotkb:DCJDKEDG_00010(orf name)|uniprotkb:DILPLKIK_00010(orf name)|uniprotkb:DJCKHMNK_00010(orf name)|uniprotkb:NBBNDGNH_00010(orf name)|uniprotkb:NCKHNGOI_00010(orf name)|uniprotkb:NFOBEAPH_00010(orf name)|uniprotkb:OCMKPLLD_00010(orf name)|uniprotkb:OHMFJBFK_00010(orf name)	psi-mi:"MI:0663"(confocal microscopy)	Sharmin et al. (2016)	pubmed:26889034|imex:IM-25966	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:10320(Bovine herpesvirus 1)|taxid:10320(Bovine herpesvirus 1)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-11896743|imex:IM-25966-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR022752|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|interpro:IPR038295|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860	interpro:IPR005029(Herpesvirus UL47 protein)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0042025"(host cell nucleus)	go:"GO:0030430"(host cell cytoplasm)	-	-	figure legend:9 and 10|comment:In the absence of VP8,  Ifn-beta treatment resulted in nuclear localisation of STAT1.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9913(bovin-mdbk)|taxid:9913(Bos taurus)	-	2016/07/25	2016/07/25	rogid:aKUAQrvkbhJKI5tF5fTWNhwF7qA9913	rogid:Vu0N4WHtxZwh0AxlKrrZbB+Qge010320	rigid:8lnBV4FqoT7bzP9wfHHd3Ke1Uec	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q4R4G2	uniprotkb:Q4VW77	intact:EBI-6600948	intact:EBI-11499224	psi-mi:q4r4g2_chlae(display_long)|uniprotkb:STAT1 alpha(gene name)|psi-mi:STAT1 alpha(display_short)	psi-mi:q4vw77_9alph(display_long)|uniprotkb:UL47(gene name)|psi-mi:UL47(display_short)|uniprotkb:AAADCAAH_00010(orf name)|uniprotkb:BLEONNCJ_00010(orf name)|uniprotkb:BLPDLEPH_00010(orf name)|uniprotkb:DCJDKEDG_00010(orf name)|uniprotkb:DILPLKIK_00010(orf name)|uniprotkb:DJCKHMNK_00010(orf name)|uniprotkb:NBBNDGNH_00010(orf name)|uniprotkb:NCKHNGOI_00010(orf name)|uniprotkb:NFOBEAPH_00010(orf name)|uniprotkb:OCMKPLLD_00010(orf name)|uniprotkb:OHMFJBFK_00010(orf name)	psi-mi:"MI:0663"(confocal microscopy)	Sharmin et al. (2016)	pubmed:26889034|imex:IM-25966	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	taxid:10320(Bovine herpesvirus 1)|taxid:10320(Bovine herpesvirus 1)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12501924|imex:IM-25966-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|interpro:IPR035859|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022752|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR038295|interpro:IPR036535|interpro:IPR036860	interpro:IPR005029(Herpesvirus UL47 protein)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0042025"(host cell nucleus)	go:"GO:0030430"(host cell cytoplasm)	-	-	figure legend:8|comment:In almost all  cells that expressed full length VP8, or VP8 minus the NLS,  STAT1 remained cytoplasmic, before or after IFN-beta treatment.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells")	-	2016/07/25	2016/08/10	rogid:tvFFTVF7PHT3BGaSnAkHO/UIWMg9534	rogid:Vu0N4WHtxZwh0AxlKrrZbB+Qge010320	rigid:d4Hgo8clT4dJOdHbZ7g0JsEZBy0	false	-	flag tag:n-n|sufficient binding region:219-741	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)