#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NVV9	uniprotkb:Q9NUQ8	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-717672|uniprotkb:Q86UA2|uniprotkb:Q8NAN1|uniprotkb:Q96GS8|uniprotkb:Q9H7A8|uniprotkb:A8K241|ensembl:ENSP00000411471	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:abcf3_human(display_long)|uniprotkb:ABCF3(gene name)|psi-mi:ABCF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463877	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_060828.2|ensembl:ENSG00000161204(gene)|ensembl:ENST00000429586(transcript)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0005524"(ATP binding)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|go:"GO:0016020"(membrane)|mint:Q9NUQ8|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR003439(ABC transporter-like)|entrezgene/locuslink:55324(identity)	intact:EBI-16432406(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:lCleN3/TzwUbPMZzkKRJzNygge89606	rigid:z3DCG+LS3ZkLK7CT5jMtr1cjZUE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:A0A0S2Z645	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16432404	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:a0a0s2z645_human(display_long)|uniprotkb:ABCF3(gene name)|psi-mi:ABCF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463861	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	go:"GO:0005524"(ATP binding)|interpro:IPR003439(ABC transporter-like)|interpro:IPR027417|entrezgene/locuslink:55324(identity)	intact:EBI-16429865(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:LUXhV0mfHbsf8mpOg/NiZs9wjgY9606	rigid:fBvZehgUFGbuAJOfeOCPumeHL2k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61289	uniprotkb:Q9NUQ8	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	intact:EBI-717672|uniprotkb:Q86UA2|uniprotkb:Q8NAN1|uniprotkb:Q96GS8|uniprotkb:Q9H7A8|uniprotkb:A8K241|ensembl:ENSP00000411471	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:abcf3_human(display_long)|uniprotkb:ABCF3(gene name)|psi-mi:ABCF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463909	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|entrezgene/locuslink:10197(identity)	refseq:NP_060828.2|ensembl:ENSG00000161204(gene)|ensembl:ENST00000429586(transcript)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0005524"(ATP binding)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|go:"GO:0016020"(membrane)|mint:Q9NUQ8|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR003439(ABC transporter-like)|entrezgene/locuslink:55324(identity)	intact:EBI-16434200(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:lCleN3/TzwUbPMZzkKRJzNygge89606	rigid:UAIzPgFd55gU0U/qzKLjthwbCrc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:Q9NUQ8	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-717672|uniprotkb:Q86UA2|uniprotkb:Q8NAN1|uniprotkb:Q96GS8|uniprotkb:Q9H7A8|uniprotkb:A8K241|ensembl:ENSP00000411471	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:abcf3_human(display_long)|uniprotkb:ABCF3(gene name)|psi-mi:ABCF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463925	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	refseq:NP_060828.2|ensembl:ENSG00000161204(gene)|ensembl:ENST00000429586(transcript)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0005524"(ATP binding)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|go:"GO:0016020"(membrane)|mint:Q9NUQ8|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR003439(ABC transporter-like)|entrezgene/locuslink:55324(identity)	intact:EBI-16435052(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:lCleN3/TzwUbPMZzkKRJzNygge89606	rigid:H84lLCCKKriRrGaEaXl3Rgy5Y8A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P50221	uniprotkb:Q8NC06-3	intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684	intact:EBI-12811089|ensembl:ENSP00000405969|ensembl:ENSP00000465484|ensembl:ENSP00000465610	psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym)	psi-mi:q8nc06-3(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463941	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity)	ensembl:ENSG00000181513(gene)|ensembl:ENST00000431281(transcript)|ensembl:ENST00000586346(transcript)|ensembl:ENST00000591859(transcript)|intact:EBI-11288411(isoform-parent)|uniprotkb:Q8NC06-3(isoform-parent)|uniprotkb:Q8NC06(isoform-parent)|entrezgene/locuslink:79777(identity)	intact:EBI-16431309(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606	rogid:3B+wNzSVplS3qK5wXZj4EdiPcHU9606	rigid:a1jKG0mAeoqOuB6wRWdfZfGkWyY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P50221	uniprotkb:A0A0S2Z5W7	intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684	intact:EBI-16439276	psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym)	psi-mi:a0a0s2z5w7_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463957	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity)	go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|refseq:XP_006722148.1|interpro:IPR035984|entrezgene/locuslink:79777(identity)	intact:EBI-16431309(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606	rogid:HNnpsSnhfzjAoJRLrRJcCTSb45o9606	rigid:kuBqfD3GDDtoLp2m6E9muMgj7qQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P50221	uniprotkb:Q8NC06	intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684	intact:EBI-11288411|uniprotkb:D3DX64|uniprotkb:Q8IUT1|uniprotkb:Q9H8Q4|ensembl:ENSP00000366154|ensembl:ENSP00000482750|intact:EBI-16463973	psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym)	psi-mi:acbd4_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463976	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity)	refseq:NP_001129177.1|refseq:NP_001129178.1|refseq:NP_001129179.1|refseq:NP_078998.1|refseq:NP_001308281.1|refseq:NP_001308282.1|refseq:XP_016880577.1|refseq:XP_016880580.1|refseq:XP_016880581.1|ensembl:ENSG00000181513(gene)|ensembl:ENST00000376955(transcript)|ensembl:ENST00000619916(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0008289"(lipid binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|rcsb pdb:2WH5|reactome:R-HSA-390918|entrezgene/locuslink:79777(identity)	intact:EBI-16431309(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606	rogid:GtdCbchDgfXEHVgEUU7JnVpA7DQ9606	rigid:pMWfy772sh+KNDjkDk/vu8Uopmw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HAQ2	uniprotkb:Q8NC06-3	intact:EBI-8472129|intact:MINT-8417679|uniprotkb:Q9H8A4|uniprotkb:Q86Z28|ensembl:ENSP00000265529|ensembl:ENSP00000391100|ensembl:ENSP00000507186	intact:EBI-12811089|ensembl:ENSP00000405969|ensembl:ENSP00000465484|ensembl:ENSP00000465610	psi-mi:kif9_human(display_long)|uniprotkb:KIF9(gene name)|psi-mi:KIF9(display_short)	psi-mi:q8nc06-3(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463992	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011532306.1|refseq:NP_071737.1|refseq:NP_001128350.1|refseq:NP_878905.2|refseq:XP_016862518.1|ensembl:ENSG00000088727(gene)|ensembl:ENST00000265529(transcript)|ensembl:ENST00000452770(transcript)|ensembl:ENST00000684063(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:1903008"(organelle disassembly)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q9HAQ2|rcsb pdb:3NWN|reactome:R-HSA-6811434|reactome:R-HSA-983189|entrezgene/locuslink:64147(identity)	ensembl:ENSG00000181513(gene)|ensembl:ENST00000431281(transcript)|ensembl:ENST00000586346(transcript)|ensembl:ENST00000591859(transcript)|intact:EBI-11288411(isoform-parent)|uniprotkb:Q8NC06-3(isoform-parent)|uniprotkb:Q8NC06(isoform-parent)|entrezgene/locuslink:79777(identity)	intact:EBI-16432580(see-also)	comment:mint|comment:homomint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:53+NnzzIaB0e+FlgTdFXGvetKtg9606	rogid:3B+wNzSVplS3qK5wXZj4EdiPcHU9606	rigid:fHyscIUKPzE5Pmb9q0Ks4YU66Y4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HAQ2	uniprotkb:A0A0S2Z5W7	intact:EBI-8472129|intact:MINT-8417679|uniprotkb:Q9H8A4|uniprotkb:Q86Z28|ensembl:ENSP00000265529|ensembl:ENSP00000391100|ensembl:ENSP00000507186	intact:EBI-16439276	psi-mi:kif9_human(display_long)|uniprotkb:KIF9(gene name)|psi-mi:KIF9(display_short)	psi-mi:a0a0s2z5w7_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464008	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011532306.1|refseq:NP_071737.1|refseq:NP_001128350.1|refseq:NP_878905.2|refseq:XP_016862518.1|ensembl:ENSG00000088727(gene)|ensembl:ENST00000265529(transcript)|ensembl:ENST00000452770(transcript)|ensembl:ENST00000684063(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:1903008"(organelle disassembly)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q9HAQ2|rcsb pdb:3NWN|reactome:R-HSA-6811434|reactome:R-HSA-983189|entrezgene/locuslink:64147(identity)	go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|refseq:XP_006722148.1|interpro:IPR035984|entrezgene/locuslink:79777(identity)	intact:EBI-16432580(see-also)	comment:mint|comment:homomint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:53+NnzzIaB0e+FlgTdFXGvetKtg9606	rogid:HNnpsSnhfzjAoJRLrRJcCTSb45o9606	rigid:p3F+p9dQoeO/9dhRV/qA/E+G66w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HAQ2	uniprotkb:Q8NC06	intact:EBI-8472129|intact:MINT-8417679|uniprotkb:Q9H8A4|uniprotkb:Q86Z28|ensembl:ENSP00000265529|ensembl:ENSP00000391100|ensembl:ENSP00000507186	intact:EBI-11288411|uniprotkb:D3DX64|uniprotkb:Q8IUT1|uniprotkb:Q9H8Q4|ensembl:ENSP00000366154|ensembl:ENSP00000482750|intact:EBI-16463973	psi-mi:kif9_human(display_long)|uniprotkb:KIF9(gene name)|psi-mi:KIF9(display_short)	psi-mi:acbd4_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464024	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011532306.1|refseq:NP_071737.1|refseq:NP_001128350.1|refseq:NP_878905.2|refseq:XP_016862518.1|ensembl:ENSG00000088727(gene)|ensembl:ENST00000265529(transcript)|ensembl:ENST00000452770(transcript)|ensembl:ENST00000684063(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:1903008"(organelle disassembly)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q9HAQ2|rcsb pdb:3NWN|reactome:R-HSA-6811434|reactome:R-HSA-983189|entrezgene/locuslink:64147(identity)	refseq:NP_001129177.1|refseq:NP_001129178.1|refseq:NP_001129179.1|refseq:NP_078998.1|refseq:NP_001308281.1|refseq:NP_001308282.1|refseq:XP_016880577.1|refseq:XP_016880580.1|refseq:XP_016880581.1|ensembl:ENSG00000181513(gene)|ensembl:ENST00000376955(transcript)|ensembl:ENST00000619916(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0008289"(lipid binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|rcsb pdb:2WH5|reactome:R-HSA-390918|entrezgene/locuslink:79777(identity)	intact:EBI-16432580(see-also)	comment:mint|comment:homomint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:53+NnzzIaB0e+FlgTdFXGvetKtg9606	rogid:GtdCbchDgfXEHVgEUU7JnVpA7DQ9606	rigid:wa1KZ4o42ubKnhyIhbRnHOzwcu0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:Q8NC06-3	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-12811089|ensembl:ENSP00000405969|ensembl:ENSP00000465484|ensembl:ENSP00000465610	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:q8nc06-3(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464040	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	ensembl:ENSG00000181513(gene)|ensembl:ENST00000431281(transcript)|ensembl:ENST00000586346(transcript)|ensembl:ENST00000591859(transcript)|intact:EBI-11288411(isoform-parent)|uniprotkb:Q8NC06-3(isoform-parent)|uniprotkb:Q8NC06(isoform-parent)|entrezgene/locuslink:79777(identity)	intact:EBI-16433303(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:3B+wNzSVplS3qK5wXZj4EdiPcHU9606	rigid:Y2WnEM4IXKqL0lIun0e+UYGIVcM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:A0A0S2Z5W7	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-16439276	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:a0a0s2z5w7_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464056	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|refseq:XP_006722148.1|interpro:IPR035984|entrezgene/locuslink:79777(identity)	intact:EBI-16433303(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:HNnpsSnhfzjAoJRLrRJcCTSb45o9606	rigid:34E8NEbJzAcYHMoD4f8LjJWco/Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:Q8NC06	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-11288411|uniprotkb:D3DX64|uniprotkb:Q8IUT1|uniprotkb:Q9H8Q4|ensembl:ENSP00000366154|ensembl:ENSP00000482750|intact:EBI-16463973	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:acbd4_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464072	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	refseq:NP_001129177.1|refseq:NP_001129178.1|refseq:NP_001129179.1|refseq:NP_078998.1|refseq:NP_001308281.1|refseq:NP_001308282.1|refseq:XP_016880577.1|refseq:XP_016880580.1|refseq:XP_016880581.1|ensembl:ENSG00000181513(gene)|ensembl:ENST00000376955(transcript)|ensembl:ENST00000619916(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0008289"(lipid binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|rcsb pdb:2WH5|reactome:R-HSA-390918|entrezgene/locuslink:79777(identity)	intact:EBI-16433303(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:GtdCbchDgfXEHVgEUU7JnVpA7DQ9606	rigid:4lVHE43HkhHsQPGeBgIXg2Ag/bM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:Q8NC06-3	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-12811089|ensembl:ENSP00000405969|ensembl:ENSP00000465484|ensembl:ENSP00000465610	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:q8nc06-3(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464088	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	ensembl:ENSG00000181513(gene)|ensembl:ENST00000431281(transcript)|ensembl:ENST00000586346(transcript)|ensembl:ENST00000591859(transcript)|intact:EBI-11288411(isoform-parent)|uniprotkb:Q8NC06-3(isoform-parent)|uniprotkb:Q8NC06(isoform-parent)|entrezgene/locuslink:79777(identity)	intact:EBI-16435658(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:3B+wNzSVplS3qK5wXZj4EdiPcHU9606	rigid:8u90uFjZeSf3NTigJAs3LmQzpko	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:A0A0S2Z5W7	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-16439276	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:a0a0s2z5w7_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464104	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|refseq:XP_006722148.1|interpro:IPR035984|entrezgene/locuslink:79777(identity)	intact:EBI-16435658(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:HNnpsSnhfzjAoJRLrRJcCTSb45o9606	rigid:WupXLsT/fqjlN0zVQVSY86SYrTM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:Q8NC06	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-11288411|uniprotkb:D3DX64|uniprotkb:Q8IUT1|uniprotkb:Q9H8Q4|ensembl:ENSP00000366154|ensembl:ENSP00000482750|intact:EBI-16463973	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:acbd4_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	refseq:NP_001129177.1|refseq:NP_001129178.1|refseq:NP_001129179.1|refseq:NP_078998.1|refseq:NP_001308281.1|refseq:NP_001308282.1|refseq:XP_016880577.1|refseq:XP_016880580.1|refseq:XP_016880581.1|ensembl:ENSG00000181513(gene)|ensembl:ENST00000376955(transcript)|ensembl:ENST00000619916(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0008289"(lipid binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|rcsb pdb:2WH5|reactome:R-HSA-390918|entrezgene/locuslink:79777(identity)	intact:EBI-16435658(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:GtdCbchDgfXEHVgEUU7JnVpA7DQ9606	rigid:4tUNKovV1oeDpJfUCGYPxQWIl8Y	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:Q8NC06-3	intact:EBI-16439278	intact:EBI-12811089|ensembl:ENSP00000405969|ensembl:ENSP00000465484|ensembl:ENSP00000465610	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:q8nc06-3(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464136	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	ensembl:ENSG00000181513(gene)|ensembl:ENST00000431281(transcript)|ensembl:ENST00000586346(transcript)|ensembl:ENST00000591859(transcript)|intact:EBI-11288411(isoform-parent)|uniprotkb:Q8NC06-3(isoform-parent)|uniprotkb:Q8NC06(isoform-parent)|entrezgene/locuslink:79777(identity)	intact:EBI-16439289(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:3B+wNzSVplS3qK5wXZj4EdiPcHU9606	rigid:okrjLyPD+lP7YCJ3ndkHWHncgxk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:Q8NC06	intact:EBI-16439278	intact:EBI-11288411|uniprotkb:D3DX64|uniprotkb:Q8IUT1|uniprotkb:Q9H8Q4|ensembl:ENSP00000366154|ensembl:ENSP00000482750|intact:EBI-16463973	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:acbd4_human(display_long)|uniprotkb:ACBD4(gene name)|psi-mi:ACBD4(display_short)|uniprotkb:HMFT0700(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464152	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	refseq:NP_001129177.1|refseq:NP_001129178.1|refseq:NP_001129179.1|refseq:NP_078998.1|refseq:NP_001308281.1|refseq:NP_001308282.1|refseq:XP_016880577.1|refseq:XP_016880580.1|refseq:XP_016880581.1|ensembl:ENSG00000181513(gene)|ensembl:ENST00000376955(transcript)|ensembl:ENST00000619916(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0008289"(lipid binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|rcsb pdb:2WH5|reactome:R-HSA-390918|entrezgene/locuslink:79777(identity)	intact:EBI-16439289(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:GtdCbchDgfXEHVgEUU7JnVpA7DQ9606	rigid:fovy9MT8NydHLCiJx3MlDPu1i6o	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:Q9NUQ8	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-717672|uniprotkb:Q86UA2|uniprotkb:Q8NAN1|uniprotkb:Q96GS8|uniprotkb:Q9H7A8|uniprotkb:A8K241|ensembl:ENSP00000411471	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:abcf3_human(display_long)|uniprotkb:ABCF3(gene name)|psi-mi:ABCF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16463893	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	refseq:NP_060828.2|ensembl:ENSG00000161204(gene)|ensembl:ENST00000429586(transcript)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0005524"(ATP binding)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|go:"GO:0016020"(membrane)|mint:Q9NUQ8|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR003439(ABC transporter-like)|entrezgene/locuslink:55324(identity)	intact:EBI-16433714(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:lCleN3/TzwUbPMZzkKRJzNygge89606	rigid:z6SDo5ZJlomDoVXTHLU51VWV2SQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P50542-3	uniprotkb:Q9ULJ7-2	intact:EBI-12181987|ensembl:ENSP00000266564|ensembl:ENSP00000500230	intact:EBI-12239063|ensembl:ENSP00000425355	psi-mi:p50542-3(display_long)|uniprotkb:PEX5(gene name)|psi-mi:PEX5(display_short)|uniprotkb:PTS1-BP(gene name synonym)|uniprotkb:PXR1(gene name synonym)|uniprotkb:Peroxin-5(gene name synonym)|uniprotkb:Peroxisomal C-terminal targeting signal import receptor(gene name synonym)|uniprotkb:Peroxisome receptor 1(gene name synonym)	psi-mi:q9ulj7-2(display_long)|uniprotkb:ANKRD50(gene name)|psi-mi:ANKRD50(display_short)|uniprotkb:KIAA1223(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464332	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-597835(isoform-parent)|uniprotkb:P50542-3(isoform-parent)|ensembl:ENSG00000139197(gene)|ensembl:ENSG00000288217(gene)|ensembl:ENST00000266564(transcript)|ensembl:ENST00000672776(transcript)|entrezgene/locuslink:5830(identity)	intact:EBI-5653671(isoform-parent)|uniprotkb:Q9ULJ7-2(isoform-parent)|ensembl:ENSG00000151458(gene)|ensembl:ENST00000515641(transcript)|entrezgene/locuslink:57182(identity)	intact:EBI-16433395(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:HHmRC1+icpDic4lf7z1DLsXG/gY9606	rogid:vF7ybJTcu6xrDedqEvvMz+15f3Y9606	rigid:jzZZwZ6yey6fym6J4qhv8p0XJrk	true	-	sufficient binding region:508-1250	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y4X0	uniprotkb:Q6FHY5	intact:EBI-8583355|ensembl:ENSP00000262844|uniprotkb:Q8WX22|intact:MINT-3086664|uniprotkb:Q5JYV9|uniprotkb:Q6P9D8|uniprotkb:Q9UIQ8	intact:EBI-16439278	psi-mi:ammr1_human(display_long)|uniprotkb:AMMECR1(gene name)|psi-mi:AMMECR1(display_short)	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464316	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101935(gene)|ensembl:ENST00000262844(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|interpro:IPR002733(AMMECR1)|interpro:IPR023473|interpro:IPR027485|interpro:IPR036071|mint:Q9Y4X0|refseq:NP_001020751.1|refseq:NP_056180.1|refseq:NP_001165160.1|entrezgene/locuslink:9949(identity)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	intact:EBI-16439299(see-also)	comment:mint|comment:homomint|function:"Defects in AMMECR1 may be a cause of AMME complex [MIM:300194]; also known as Alport syndrome with mental retardation, midface hypoplasia and elliptocytosis. The AMME complex is a contiguous gene deletion syndrome"	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:epeJrGQt5CbnPII1/FSttS0KzwE9606	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rigid:JRTxJMggk5NoA0L3DkjM6f4vA6c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95967	uniprotkb:Q9Y4X0-3	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953|ensembl:ENSP00000435295	intact:EBI-12823597|ensembl:ENSP00000361129	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:q9y4x0-3(display_long)|uniprotkb:AMMECR1(gene name)|psi-mi:AMMECR1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464300	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_058634.4|ensembl:ENSG00000172638(gene)|ensembl:ENST00000307998(transcript)|ensembl:ENST00000531972(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008201"(heparin binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035904"(aorta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071953"(elastic fiber)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904026"(regulation of collagen fibril organization)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904831"(positive regulation of aortic smooth muscle cell differentiation)|go:"GO:1905609"(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR026824|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|dip:DIP-34518N|entrezgene/locuslink:30008(identity)	uniprotkb:Q9Y4X0-3(isoform-parent)|ensembl:ENSG00000101935(gene)|ensembl:ENST00000372059(transcript)|intact:EBI-8583355(isoform-parent)|entrezgene/locuslink:9949(identity)	intact:EBI-16433227(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:lLHOM38DC5g4w13Mv5lvL9Ci6Ec9606	rigid:p+gCaNkGJbBQAk96n6i3aYaUncI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q9Y4X0-3	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-12823597|ensembl:ENSP00000361129	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:q9y4x0-3(display_long)|uniprotkb:AMMECR1(gene name)|psi-mi:AMMECR1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464284	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	uniprotkb:Q9Y4X0-3(isoform-parent)|ensembl:ENSG00000101935(gene)|ensembl:ENST00000372059(transcript)|intact:EBI-8583355(isoform-parent)|entrezgene/locuslink:9949(identity)	intact:EBI-16432098(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:lLHOM38DC5g4w13Mv5lvL9Ci6Ec9606	rigid:ckur0mjrtKfJI7kWjGEHJY+zBrc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P31749	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-296087|uniprotkb:Q9BWB6|ensembl:ENSP00000270202|ensembl:ENSP00000384293|ensembl:ENSP00000385326|ensembl:ENSP00000450688|ensembl:ENSP00000451166|ensembl:ENSP00000451828|ensembl:ENSP00000507879|ensembl:ENSP00000497822|uniprotkb:B2RAM5|uniprotkb:B7Z5R1	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:akt1_human(display_long)|uniprotkb:AKT1(gene name)|psi-mi:AKT1(display_short)|uniprotkb:PKB(gene name synonym)|uniprotkb:RAC(gene name synonym)|uniprotkb:RAC-PK-alpha(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym)|uniprotkb:Proto-oncogene c-Akt(gene name synonym)|uniprotkb:Protein kinase B alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464268	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0009408"(response to heat)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0007568"(aging)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|ensembl:ENSG00000142208(gene)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0031982"(vesicle)|go:"GO:0031999"(negative regulation of fatty acid beta-oxidation)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032094"(response to food)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|ensembl:ENST00000349310(transcript)|ensembl:ENST00000402615(transcript)|ensembl:ENST00000407796(transcript)|ensembl:ENST00000554581(transcript)|ensembl:ENST00000554848(transcript)|ensembl:ENST00000555528(transcript)|ensembl:ENST00000649815(transcript)|ensembl:ENST00000683722(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007281"(germ cell development)|go:"GO:0005739"(mitochondrion)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060709"(glycogen cell differentiation involved in embryonic placenta development)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0070141"(response to UV-A)|go:"GO:0070848"(response to growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0098794"(postsynapse)|go:"GO:0099104"(potassium channel activator activity)|go:"GO:0100002"(negative regulation of protein kinase activity by protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034676|interpro:IPR039026|interpro:IPR039027|mint:P31749|rcsb pdb:1H10|rcsb pdb:1UNP|rcsb pdb:1UNQ|reactome:R-HSA-1474151|reactome:R-HSA-165159|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418|reactome:R-HSA-203615|reactome:R-HSA-211163|reactome:R-HSA-354192|reactome:R-HSA-3769402|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-450385|reactome:R-HSA-450604|reactome:R-HSA-5218920|rcsb pdb:6S9X|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-111447|reactome:R-HSA-6785807|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-1445148|reactome:R-HSA-6811558|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8849469|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9009391|rcsb pdb:1UNR|rcsb pdb:2UVM|rcsb pdb:2UZR|rcsb pdb:2UZS|rcsb pdb:3CQU|rcsb pdb:3CQW|rcsb pdb:3MV5|rcsb pdb:3MVH|rcsb pdb:3O96|rcsb pdb:3OCB|rcsb pdb:3OW4|rcsb pdb:3QKK|rcsb pdb:3QKL|rcsb pdb:3QKM|rcsb pdb:4EJN|rcsb pdb:4EKK|rcsb pdb:4EKL|rcsb pdb:4GV1|rcsb pdb:5KCV|rcsb pdb:6BUU|rcsb pdb:6CCY|rcsb pdb:6HHF|rcsb pdb:6HHG|rcsb pdb:6HHH|rcsb pdb:6HHI|rcsb pdb:6HHJ|rcsb pdb:6NPZ|rcsb pdb:6S9W|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|reactome:R-HSA-9604323|refseq:NP_001014431.1|refseq:NP_001014432.1|refseq:NP_005154.2|refseq:XP_005267458.1|dip:DIP-24269N|entrezgene/locuslink:207(identity)	intact:EBI-16440828(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:9bYBB1SbEBm+NM0maKOC5Bx6KlI9606	rigid:ruA0QdGBkyEQDYPkkYEF4UTqqP4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-10177480	uniprotkb:P31749	-	intact:EBI-296087|uniprotkb:Q9BWB6|ensembl:ENSP00000270202|ensembl:ENSP00000384293|ensembl:ENSP00000385326|ensembl:ENSP00000450688|ensembl:ENSP00000451166|ensembl:ENSP00000451828|ensembl:ENSP00000507879|ensembl:ENSP00000497822|uniprotkb:B2RAM5|uniprotkb:B7Z5R1	psi-mi:clone_11897(display_short)|psi-mi:EBI-10177480(display_long)|uniprotkb:Cerebral protein 11(gene name synonym)|uniprotkb:KIAA0481(gene name synonym)|uniprotkb:hucep-11(orf name)|uniprotkb:TMCC2(gene name)|psi-mi:TMCC2(display_short)	psi-mi:akt1_human(display_long)|uniprotkb:AKT1(gene name)|psi-mi:AKT1(display_short)|uniprotkb:PKB(gene name synonym)|uniprotkb:RAC(gene name synonym)|uniprotkb:RAC-PK-alpha(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym)|uniprotkb:Proto-oncogene c-Akt(gene name synonym)|uniprotkb:Protein kinase B alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464252	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:O75069-4(see-also)|intact:EBI-12696212(see-also)|intact:EBI-726731(see-also)|entrezgene/locuslink:9911(identity)	go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0009408"(response to heat)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0007568"(aging)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|ensembl:ENSG00000142208(gene)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0031982"(vesicle)|go:"GO:0031999"(negative regulation of fatty acid beta-oxidation)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032094"(response to food)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|ensembl:ENST00000349310(transcript)|ensembl:ENST00000402615(transcript)|ensembl:ENST00000407796(transcript)|ensembl:ENST00000554581(transcript)|ensembl:ENST00000554848(transcript)|ensembl:ENST00000555528(transcript)|ensembl:ENST00000649815(transcript)|ensembl:ENST00000683722(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007281"(germ cell development)|go:"GO:0005739"(mitochondrion)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060709"(glycogen cell differentiation involved in embryonic placenta development)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0070141"(response to UV-A)|go:"GO:0070848"(response to growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0098794"(postsynapse)|go:"GO:0099104"(potassium channel activator activity)|go:"GO:0100002"(negative regulation of protein kinase activity by protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034676|interpro:IPR039026|interpro:IPR039027|mint:P31749|rcsb pdb:1H10|rcsb pdb:1UNP|rcsb pdb:1UNQ|reactome:R-HSA-1474151|reactome:R-HSA-165159|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418|reactome:R-HSA-203615|reactome:R-HSA-211163|reactome:R-HSA-354192|reactome:R-HSA-3769402|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-450385|reactome:R-HSA-450604|reactome:R-HSA-5218920|rcsb pdb:6S9X|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-111447|reactome:R-HSA-6785807|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-1445148|reactome:R-HSA-6811558|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8849469|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9009391|rcsb pdb:1UNR|rcsb pdb:2UVM|rcsb pdb:2UZR|rcsb pdb:2UZS|rcsb pdb:3CQU|rcsb pdb:3CQW|rcsb pdb:3MV5|rcsb pdb:3MVH|rcsb pdb:3O96|rcsb pdb:3OCB|rcsb pdb:3OW4|rcsb pdb:3QKK|rcsb pdb:3QKL|rcsb pdb:3QKM|rcsb pdb:4EJN|rcsb pdb:4EKK|rcsb pdb:4EKL|rcsb pdb:4GV1|rcsb pdb:5KCV|rcsb pdb:6BUU|rcsb pdb:6CCY|rcsb pdb:6HHF|rcsb pdb:6HHG|rcsb pdb:6HHH|rcsb pdb:6HHI|rcsb pdb:6HHJ|rcsb pdb:6NPZ|rcsb pdb:6S9W|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|reactome:R-HSA-9604323|refseq:NP_001014431.1|refseq:NP_001014432.1|refseq:NP_005154.2|refseq:XP_005267458.1|dip:DIP-24269N|entrezgene/locuslink:207(identity)	intact:EBI-16430472(see-also)	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/22	rogid:hIJ1KAUaIyjszZvvmcTXV6Nox8o9606	rogid:9bYBB1SbEBm+NM0maKOC5Bx6KlI9606	rigid:inJCrqJY5vATY8nElu6HXfZwBCY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P31323	uniprotkb:A0A0S2Z5A1	intact:EBI-2930670|ensembl:ENSP00000265717|ensembl:ENSP00000491687|uniprotkb:A4D0R9	intact:EBI-16464200	psi-mi:kap3_human(display_long)|uniprotkb:PRKAR2B(gene name)|psi-mi:PRKAR2B(display_short)	psi-mi:a0a0s2z5a1_human(display_long)|uniprotkb:AKAP10(gene name)|psi-mi:AKAP10(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464235	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000005249(gene)|ensembl:ENSG00000284096(gene)|ensembl:ENST00000265717(transcript)|ensembl:ENST00000639737(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0007612"(learning)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P31323|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|refseq:NP_002727.2|dip:DIP-554N|entrezgene/locuslink:5577(identity)	go:"GO:0016301"(kinase activity)|entrezgene/locuslink:11216(identity)	intact:EBI-16431706(see-also)|intact:EBI-16431721(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:P643dCCYtpt/EkR7tmZrbo97FLE9606	rogid:xFdTRYl8qw6Ue2e94+e/kOyic3A9606	rigid:5KO+2BTLTOEa6bqNXOG+9D/snAI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:A0A0S2Z551	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-16431716	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:a0a0s2z551_human(display_long)|uniprotkb:AKAP10(gene name)|psi-mi:AKAP10(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464219	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0051018"(protein kinase A binding)|interpro:IPR037719|entrezgene/locuslink:11216(identity)	intact:EBI-16428928(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:O6Li2aTpDpFy7i6Ia/aZ/+E95iE9606	rigid:rUft2z4F9+7j93SKFlsHZk8UPNM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:A0A0S2Z5A1	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-16464200	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:a0a0s2z5a1_human(display_long)|uniprotkb:AKAP10(gene name)|psi-mi:AKAP10(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464203	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	go:"GO:0016301"(kinase activity)|entrezgene/locuslink:11216(identity)	intact:EBI-16428928(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:xFdTRYl8qw6Ue2e94+e/kOyic3A9606	rigid:VghsukR1voK/uKzmq639Jx44fks	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NPC6	uniprotkb:A0A0S2Z3G1	intact:EBI-746712|uniprotkb:O43415|uniprotkb:Q9HB92|ensembl:ENSP00000306997	intact:EBI-16430749	psi-mi:myoz2_human(display_long)|uniprotkb:Calsarcin-1(gene name synonym)|uniprotkb:FATZ-related protein 2(gene name synonym)|uniprotkb:MYOZ2(gene name)|psi-mi:MYOZ2(display_short)|uniprotkb:C4orf5(gene name synonym)	psi-mi:a0a0s2z3g1_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464184	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057683.1|ensembl:ENSG00000172399(gene)|ensembl:ENST00000307128(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003779"(actin binding)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031433"(telethonin binding)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051373"(FATZ binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR008438(Calcineurin-binding)|entrezgene/locuslink:51778(identity)	entrezgene/locuslink:81(identity)	intact:EBI-16439028(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Y2B5tDM2oGscI8xiTwB69hFEhL89606	rogid:cBkc6vvPxaFNKnw/GZkKFkGYW5I9606	rigid:1Rmf3VjG47s27Au2CKav4P+m0fc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:O43707	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-351526|uniprotkb:O76048|uniprotkb:D6PXK4|ensembl:ENSP00000252699|ensembl:ENSP00000489220|uniprotkb:A4K467	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:actn4_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464168	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	refseq:NP_004915.2|ensembl:ENSG00000130402(gene)|ensembl:ENSG00000282844(gene)|ensembl:ENST00000252699(transcript)|ensembl:ENST00000634960(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:O43707|rcsb pdb:1WLX|rcsb pdb:1YDI|rcsb pdb:2R0O|rcsb pdb:6O31|rcsb pdb:6OA6|reactome:R-HSA-114608|reactome:R-HSA-373753|dip:DIP-33179N|entrezgene/locuslink:81(identity)	intact:EBI-16430751(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:kTYezA2lEtL/AQPfCQ8BE79nzow9606	rigid:D/3niI5MABckYB1EwQvY8KlKoWs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VSY0	uniprotkb:A0A0S2Z4X7	intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550	intact:EBI-16464351	psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short)	psi-mi:a0a0s2z4x7_human(display_long)|uniprotkb:AP3B1(gene name)|psi-mi:AP3B1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464354	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N|entrezgene/locuslink:80318(identity)	go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR026739|entrezgene/locuslink:8546(identity)	intact:EBI-16438960(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WPAqDDTftv300tbwXkusTo6tmUo9606	rogid:kjlUsukeYVoZcSb+7MoA5pV5ilg9606	rigid:zJXW/f799yyXUhbV4GUccfGVtbw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14613	intact:EBI-16464370	intact:EBI-3438291|uniprotkb:Q9UNS0|uniprotkb:B2RD85|ensembl:ENSP00000279249|ensembl:ENSP00000431660	-	psi-mi:borg1_human(display_long)|uniprotkb:CDC42EP2(gene name)|psi-mi:CDC42EP2(display_short)|uniprotkb:BORG1(gene name synonym)|uniprotkb:CEP2(gene name synonym)|uniprotkb:Binder of Rho GTPases 1(gene name synonym)	psi-mi:"ccsb isoform id: arhgap26_2"(display_short)|psi-mi:EBI-16464370(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464373	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006770.1|ensembl:ENSG00000149798(gene)|ensembl:ENST00000279249(transcript)|ensembl:ENST00000533419(transcript)|go:"GO:0001515"(opioid peptide activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0012505"(endomembrane system)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR017363(Cdc42 effector protein 2)|interpro:IPR029273|reactome:R-HSA-5687128|reactome:R-HSA-9013148|reactome:R-HSA-9013406|refseq:XP_016872583.1|entrezgene/locuslink:10435(identity)	entrezgene/locuslink:23092(identity)	intact:EBI-16430972(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9oBDq+/9RNfIIl3yJWKUaxKelcs9606	rogid:RizkcONMrxJVxr6OeCJ46Hx8tKU9606	rigid:ATcgQ0tOMWLdWgg+VgHH9OHdT7o	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q53EZ4	uniprotkb:A0A0S2Z543	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	intact:EBI-16464389	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:a0a0s2z543_human(display_long)|uniprotkb:ARHGEF15(gene name)|psi-mi:ARHGEF15(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464398	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR035899|entrezgene/locuslink:22899(identity)	intact:EBI-16434808(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:g+l8vXDSIS++OznFBOdMJnkI30Q9606	rigid:xMFhNM1fWEHcAnUpz3DL9m6rQrk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P41212	uniprotkb:O15169	intact:EBI-1372759|uniprotkb:A3QVP6|uniprotkb:Q9UMF6|uniprotkb:Q9UMF7|uniprotkb:Q9UMG0|uniprotkb:A8K076|ensembl:ENSP00000379658	intact:EBI-710484|uniprotkb:Q4TT26|uniprotkb:Q4TT27|ensembl:ENSP00000262320|uniprotkb:Q86YA7|uniprotkb:Q8WVW6|uniprotkb:Q96S28	psi-mi:etv6_human(display_long)|uniprotkb:ETS translocation variant 6(gene name synonym)|uniprotkb:ETS-related protein Tel1(gene name synonym)|uniprotkb:ETV6(gene name)|psi-mi:ETV6(display_short)|uniprotkb:TEL(gene name synonym)|uniprotkb:TEL1(gene name synonym)	psi-mi:axin1_human(display_long)|uniprotkb:Axis inhibition protein 1(gene name synonym)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:AXIN(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464414	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001978.1|dip:DIP-17028N|ensembl:ENSG00000139083(gene)|ensembl:ENST00000396373(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007296"(vitellogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0097152"(mesenchymal cell apoptotic process)|interpro:IPR000418(Ets)|rcsb pdb:5L0P|rcsb pdb:7JU2|rcsb pdb:7N1O|rcsb pdb:7N2B|reactome:R-HSA-9673768|reactome:R-HSA-9703465|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|mint:P41212|rcsb pdb:1JI7|rcsb pdb:1LKY|rcsb pdb:2DAO|rcsb pdb:2QAR|rcsb pdb:2QB0|rcsb pdb:2QB1|entrezgene/locuslink:2120(identity)	refseq:NP_003493.1|refseq:NP_851393.1|ensembl:ENSG00000103126(gene)|ensembl:ENST00000262320(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034622"|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR029797|interpro:IPR032101|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|mint:O15169|rcsb pdb:1DK8|rcsb pdb:1EMU|rcsb pdb:1O9U|rcsb pdb:3ZDI|rcsb pdb:4B7T|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4NU1|rcsb pdb:5WZZ|rcsb pdb:6JCK|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5689880|reactome:R-HSA-8931987|reactome:R-HSA-8939256|reactome:R-HSA-9018519|dip:DIP-34630N|entrezgene/locuslink:8312(identity)	intact:EBI-16430351(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ekItHLbEk2Expb+mR7jHa6dPBo89606	rogid:uO+LxY/7ibIZqdd5onbfXqGAZeo9606	rigid:Up2GwGxvAWYZ3lN0ev9SV/BX8vA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H257-2	uniprotkb:A0A0S2Z4M1	intact:EBI-11530605|ensembl:ENSP00000360799	intact:EBI-16429430	psi-mi:q9h257-2(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:a0a0s2z4m1_human(display_long)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:Axis inhibition protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464430	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|uniprotkb:Q9H257-2(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000371734(transcript)|entrezgene/locuslink:64170(identity)	go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR038207|interpro:IPR029797|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR032101|interpro:IPR001158(DIX)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR043581|entrezgene/locuslink:8312(identity)	intact:EBI-16435952(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZXH7B3K5NAzF1LZaeK50ciH1RTE9606	rogid:a88vM0ThHyb/x1DAIHx9I86ppFk9606	rigid:p5u4NP8iUvjq1AqyH2ZFVedYWZc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14596-2	uniprotkb:O15169	intact:EBI-11081753|ensembl:ENSP00000467816	intact:EBI-710484|uniprotkb:Q4TT26|uniprotkb:Q4TT27|ensembl:ENSP00000262320|uniprotkb:Q86YA7|uniprotkb:Q8WVW6|uniprotkb:Q96S28	psi-mi:q14596-2(display_long)|uniprotkb:NBR1(gene name)|psi-mi:NBR1(display_short)|uniprotkb:1A13B(gene name synonym)|uniprotkb:Cell migration-inducing gene 19 protein(gene name synonym)|uniprotkb:KIAA0049(gene name synonym)|uniprotkb:M17S2(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 2(gene name synonym)|uniprotkb:Neighbor of BRCA1 gene 1 protein(gene name synonym)|uniprotkb:Protein 1A1-3B(gene name synonym)|uniprotkb:MIG19(orf name)	psi-mi:axin1_human(display_long)|uniprotkb:Axis inhibition protein 1(gene name synonym)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:AXIN(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464446	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742698(isoform-parent)|ensembl:ENSG00000188554(gene)|ensembl:ENST00000589872(transcript)|uniprotkb:Q14596-2(isoform-parent)|entrezgene/locuslink:4077(identity)	refseq:NP_003493.1|refseq:NP_851393.1|ensembl:ENSG00000103126(gene)|ensembl:ENST00000262320(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034622"|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR029797|interpro:IPR032101|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|mint:O15169|rcsb pdb:1DK8|rcsb pdb:1EMU|rcsb pdb:1O9U|rcsb pdb:3ZDI|rcsb pdb:4B7T|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4NU1|rcsb pdb:5WZZ|rcsb pdb:6JCK|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5689880|reactome:R-HSA-8931987|reactome:R-HSA-8939256|reactome:R-HSA-9018519|dip:DIP-34630N|entrezgene/locuslink:8312(identity)	intact:EBI-16437295(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:KrZKoabpN1yOvD3Bt6+CCN9Wv5g9606	rogid:uO+LxY/7ibIZqdd5onbfXqGAZeo9606	rigid:kRH7pDWAN2cnIuUQGo5+hm9S0kU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96C92-2	uniprotkb:O15169	intact:EBI-10178036|ensembl:ENSP00000298537	intact:EBI-710484|uniprotkb:Q4TT26|uniprotkb:Q4TT27|ensembl:ENSP00000262320|uniprotkb:Q86YA7|uniprotkb:Q8WVW6|uniprotkb:Q96S28	psi-mi:q96c92-2(display_long)|uniprotkb:ENTR1(gene name)|psi-mi:ENTR1(display_short)|uniprotkb:Antigen NY-CO-3(gene name synonym)|uniprotkb:SDCCAG3(gene name synonym)|uniprotkb:Serologically defined colon cancer antigen 3(gene name synonym)	psi-mi:axin1_human(display_long)|uniprotkb:Axis inhibition protein 1(gene name synonym)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:AXIN(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464462	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165689(gene)|ensembl:ENST00000298537(transcript)|intact:EBI-717093(isoform-parent)|uniprotkb:Q96C92-2(isoform-parent)|entrezgene/locuslink:10807(identity)	refseq:NP_003493.1|refseq:NP_851393.1|ensembl:ENSG00000103126(gene)|ensembl:ENST00000262320(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034622"|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR029797|interpro:IPR032101|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|mint:O15169|rcsb pdb:1DK8|rcsb pdb:1EMU|rcsb pdb:1O9U|rcsb pdb:3ZDI|rcsb pdb:4B7T|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4NU1|rcsb pdb:5WZZ|rcsb pdb:6JCK|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5689880|reactome:R-HSA-8931987|reactome:R-HSA-8939256|reactome:R-HSA-9018519|dip:DIP-34630N|entrezgene/locuslink:8312(identity)	intact:EBI-16437475(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:U/LI/NOqf74lz75tLcsSMQJAAnE9606	rogid:uO+LxY/7ibIZqdd5onbfXqGAZeo9606	rigid:HVECZLCPSZg03L8BOjsYWr56/IY	true	sufficient binding region:59-412	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96K21-3	uniprotkb:A0A0S2Z4M1	intact:EBI-10187928|ensembl:ENSP00000299173	intact:EBI-16429430	psi-mi:q96k21-3(display_long)|uniprotkb:ZFYVE19(gene name)|psi-mi:ZFYVE19(display_short)|uniprotkb:ANCHR(gene name synonym)|uniprotkb:MLL partner containing FYVE domain(gene name synonym)|uniprotkb:MPFYVE(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 19(gene name synonym)	psi-mi:a0a0s2z4m1_human(display_long)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:Axis inhibition protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464481	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166140(gene)|ensembl:ENST00000299173(transcript)|intact:EBI-6448240(isoform-parent)|entrezgene/locuslink:84936(identity)	go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR038207|interpro:IPR029797|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR032101|interpro:IPR001158(DIX)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR043581|entrezgene/locuslink:8312(identity)	intact:EBI-16439174(see-also)	isoform-comment:No experimental confirmation available. Contains a phosphoserine at position 286.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9uSIHmzDgn4qCPE8iSmYVruIUgY9606	rogid:a88vM0ThHyb/x1DAIHx9I86ppFk9606	rigid:F/6xO2n3U5i58emI0+yzmjvOSY0	true	sufficient binding region:76-403	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12933	uniprotkb:A0A0S2Z4M1	intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668	intact:EBI-16429430	psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym)	psi-mi:a0a0s2z4m1_human(display_long)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:Axis inhibition protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464500	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity)	go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR038207|interpro:IPR029797|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR032101|interpro:IPR001158(DIX)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR043581|entrezgene/locuslink:8312(identity)	intact:EBI-16440624(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606	rogid:a88vM0ThHyb/x1DAIHx9I86ppFk9606	rigid:EWPqB4NXOGu6G8E/SIvjn/vUBRk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:A0A0S2Z3F5	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16464516	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:a0a0s2z3f5_human(display_long)|uniprotkb:BAG1(gene name)|psi-mi:BAG1(display_short)|uniprotkb:hCG_30265(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464519	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	go:"GO:0051087"(chaperone binding)|interpro:IPR029071|interpro:IPR017093(Molecular chaperone regulator BAG-1)|interpro:IPR039773|entrezgene/locuslink:573(identity)	intact:EBI-16429885(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:gGnYMRMOEGnL3NKQfvuAHRMvIS49606	rigid:T833yVID2/ZZX1lu8rLm1fK2fpI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P11142	uniprotkb:A0A0S2Z3F5	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	intact:EBI-16464516	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:a0a0s2z3f5_human(display_long)|uniprotkb:BAG1(gene name)|psi-mi:BAG1(display_short)|uniprotkb:hCG_30265(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464535	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N|entrezgene/locuslink:3312(identity)	go:"GO:0051087"(chaperone binding)|interpro:IPR029071|interpro:IPR017093(Molecular chaperone regulator BAG-1)|interpro:IPR039773|entrezgene/locuslink:573(identity)	intact:EBI-16435304(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	rogid:gGnYMRMOEGnL3NKQfvuAHRMvIS49606	rigid:oe9lFbF+bMDhuR65mxgXnhpm/8A	true	sufficient binding region:61-646	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96LI6	uniprotkb:E9PJI6	intact:EBI-3957665|uniprotkb:Q17RC0|uniprotkb:Q7Z4L8|uniprotkb:Q9BZA2|uniprotkb:Q9BZA3|ensembl:ENSP00000303599|ensembl:ENSP00000306549	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:hsfy1_human(display_long)|uniprotkb:HSFY1(gene name)|psi-mi:HSFY1(display_short)|uniprotkb:HSFY2(gene name)|psi-mi:HSFY2(display_short)|uniprotkb:HSF2L(gene name synonym)|uniprotkb:HSFY(gene name synonym)|uniprotkb:Heat shock transcription factor 2-like protein(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464554	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001877.1|refseq:NP_149099.2|refseq:NP_689797.1|refseq:NP_714927.1|ensembl:ENSG00000169953(gene)|ensembl:ENSG00000172468(gene)|ensembl:ENST00000304790(transcript)|ensembl:ENST00000307393(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR027730|interpro:IPR036388|interpro:IPR036390|refseq:XP_016885520.1|entrezgene/locuslink:86614(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16429303(see-also)|intact:EBI-16429320(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:grGh9Q0MUaspNXflIH6A5orHPEs9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:Riu0x0QOlmHVjtKcbfq0kNfFqfs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96LI6	intact:EBI-16431359	intact:EBI-3957665|uniprotkb:Q17RC0|uniprotkb:Q7Z4L8|uniprotkb:Q9BZA2|uniprotkb:Q9BZA3|ensembl:ENSP00000303599|ensembl:ENSP00000306549	-	psi-mi:hsfy1_human(display_long)|uniprotkb:HSFY1(gene name)|psi-mi:HSFY1(display_short)|uniprotkb:HSFY2(gene name)|psi-mi:HSFY2(display_short)|uniprotkb:HSF2L(gene name synonym)|uniprotkb:HSFY(gene name synonym)|uniprotkb:Heat shock transcription factor 2-like protein(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464571	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001877.1|refseq:NP_149099.2|refseq:NP_689797.1|refseq:NP_714927.1|ensembl:ENSG00000169953(gene)|ensembl:ENSG00000172468(gene)|ensembl:ENST00000304790(transcript)|ensembl:ENST00000307393(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR027730|interpro:IPR036388|interpro:IPR036390|refseq:XP_016885520.1|entrezgene/locuslink:86614(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16429303(see-also)|intact:EBI-16429320(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:grGh9Q0MUaspNXflIH6A5orHPEs9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:0AsA1HYSt8wxzPgsWXtUDNKLQ5k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96LI6	uniprotkb:A0A0S2Z5G4	intact:EBI-3957665|uniprotkb:Q17RC0|uniprotkb:Q7Z4L8|uniprotkb:Q9BZA2|uniprotkb:Q9BZA3|ensembl:ENSP00000303599|ensembl:ENSP00000306549	intact:EBI-16429704	psi-mi:hsfy1_human(display_long)|uniprotkb:HSFY1(gene name)|psi-mi:HSFY1(display_short)|uniprotkb:HSFY2(gene name)|psi-mi:HSFY2(display_short)|uniprotkb:HSF2L(gene name synonym)|uniprotkb:HSFY(gene name synonym)|uniprotkb:Heat shock transcription factor 2-like protein(gene name synonym)	psi-mi:a0a0s2z5g4_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464588	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001877.1|refseq:NP_149099.2|refseq:NP_689797.1|refseq:NP_714927.1|ensembl:ENSG00000169953(gene)|ensembl:ENSG00000172468(gene)|ensembl:ENST00000304790(transcript)|ensembl:ENST00000307393(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR027730|interpro:IPR036388|interpro:IPR036390|refseq:XP_016885520.1|entrezgene/locuslink:86614(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:XP_016878869.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16429303(see-also)|intact:EBI-16429320(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_7 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:grGh9Q0MUaspNXflIH6A5orHPEs9606	rogid:B3CbJKL7yJtM34eeaCkXyqqisnQ9606	rigid:54sfxAW+hFPcqDNjvDPKm3ecPak	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96JM7-2	uniprotkb:E9PJI6	intact:EBI-11985629|ensembl:ENSP00000357121|ensembl:ENSP00000436706|ensembl:ENSP00000437185	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:q96jm7-2(display_long)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:MBT1(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464605	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96JM7-2(isoform-parent)|ensembl:ENSG00000198945(gene)|ensembl:ENST00000368139(transcript)|ensembl:ENST00000526019(transcript)|ensembl:ENST00000533560(transcript)|intact:EBI-2686809(isoform-parent)|entrezgene/locuslink:84456(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16429710(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kyV/W+LGXQyvpNVA8XqVS88scjg9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:p30fRFIYCMlacTWa9gRsmYqWS6k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96JM7-2	intact:EBI-16431359	intact:EBI-11985629|ensembl:ENSP00000357121|ensembl:ENSP00000436706|ensembl:ENSP00000437185	-	psi-mi:q96jm7-2(display_long)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:MBT1(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464621	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96JM7-2(isoform-parent)|ensembl:ENSG00000198945(gene)|ensembl:ENST00000368139(transcript)|ensembl:ENST00000526019(transcript)|ensembl:ENST00000533560(transcript)|intact:EBI-2686809(isoform-parent)|entrezgene/locuslink:84456(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16429710(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kyV/W+LGXQyvpNVA8XqVS88scjg9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:FEqP6w0nijw+nAuN7FKTxG6NQHA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96JM7-2	uniprotkb:Q8N9N5-7	intact:EBI-11985629|ensembl:ENSP00000357121|ensembl:ENSP00000436706|ensembl:ENSP00000437185	intact:EBI-16429296|ensembl:ENSP00000444352	psi-mi:q96jm7-2(display_long)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:MBT1(gene name synonym)	psi-mi:q8n9n5-7(display_long)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEND1(gene name synonym)|uniprotkb:SMAR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464637	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96JM7-2(isoform-parent)|ensembl:ENSG00000198945(gene)|ensembl:ENST00000368139(transcript)|ensembl:ENST00000526019(transcript)|ensembl:ENST00000533560(transcript)|intact:EBI-2686809(isoform-parent)|entrezgene/locuslink:84456(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000538234(transcript)|intact:EBI-744695(isoform-parent)|entrezgene/locuslink:54971(identity)	intact:EBI-16429710(see-also)	-	isoform-comment:No experimental confirmation available.	comment:"Evidence for isoform CCSB isoform ID: BANP_4 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kyV/W+LGXQyvpNVA8XqVS88scjg9606	rogid:t2jbYP8LrjN6XFcera/qV+cHUNg9606	rigid:lo+yzkwx10cVCUSMrRozAnN7R4Y	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z3K3	uniprotkb:E9PJI6	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|intact:EBI-11742841|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464653	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|dip:DIP-38044N|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000143442(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|ensembl:ENST00000271715(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|entrezgene/locuslink:23126(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16429761(see-also)|intact:EBI-16429771(see-also)|intact:EBI-16429781(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:bFzMxsTxvIvA0ZIpzqnUmIe6GSc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96QF0-7	uniprotkb:E9PJI6	intact:EBI-11984839|ensembl:ENSP00000368092	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:q96qf0-7(display_long)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464689	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96QF0-7(isoform-parent)|intact:EBI-747844(isoform-parent)|ensembl:ENSG00000127328(gene)|ensembl:ENST00000378815(transcript)|entrezgene/locuslink:117177(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16429803(see-also)|intact:EBI-16429813(see-also)	isoform-comment:No experimental confirmation available.	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:AbUJj24KJUXc9MOj/FSx+ogmdfI9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:qVwxbL/qtc1gHwsI0/sInluUTQY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z3K3	intact:EBI-16431359	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|intact:EBI-11742841|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715	-	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464671	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|dip:DIP-38044N|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000143442(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|ensembl:ENST00000271715(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|entrezgene/locuslink:23126(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16429761(see-also)|intact:EBI-16429771(see-also)|intact:EBI-16429781(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:ii6NNBDdNySCT3D570TmdMrBs0w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08050-2	uniprotkb:E9PJI6	intact:EBI-5237510|ensembl:ENSP00000354492	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:q08050-2(display_long)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:FOXM1-b(isoform synonym)|uniprotkb:FoxM1B(isoform synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465007	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-866480(isoform-parent)|ensembl:ENSG00000111206(gene)|ensembl:ENST00000361953(transcript)|entrezgene/locuslink:2305(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16434868(see-also)|intact:EBI-16434905(see-also)|intact:EBI-16434915(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OErBT+uyHfgzDn6xI1OC8CATC049606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:ClJeMYYas/DLNOW6abFOHNGUUl8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BUZ4	intact:EBI-16431359	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	-	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464988	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1|entrezgene/locuslink:9618(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16433516(see-also)|intact:EBI-16433526(see-also)|intact:EBI-16433536(see-also)|intact:EBI-16433546(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:1iZBVaBf2RHTlnMFCcxEhlhqYko	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BUZ4	uniprotkb:E9PJI6	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464969	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1|entrezgene/locuslink:9618(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16433516(see-also)|intact:EBI-16433526(see-also)|intact:EBI-16433536(see-also)|intact:EBI-16433546(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:8CCbSDS1Vxm+048AznupzQXW3ds	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	intact:EBI-16431359	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	-	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464950	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16433313(see-also)|intact:EBI-16433323(see-also)|intact:EBI-16433333(see-also)|intact:EBI-16433343(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:C11XXi5gd+6AQlZieuOxrg4LAWs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:E9PJI6	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464931	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16433313(see-also)|intact:EBI-16433323(see-also)|intact:EBI-16433333(see-also)|intact:EBI-16433343(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:tyxCVy+vKP0nDSYB+PgosCXTvtI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5TD97	uniprotkb:A0A0S2Z5G4	intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357	intact:EBI-16429704	psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym)	psi-mi:a0a0s2z5g4_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464915	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68|entrezgene/locuslink:9457(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:XP_016878869.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16432466(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_7 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606	rogid:B3CbJKL7yJtM34eeaCkXyqqisnQ9606	rigid:f1EpXrYmhkBVEXbnKjXen6vO60g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5TD97	uniprotkb:B4DE54	intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357	intact:EBI-16429313	psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym)	psi-mi:b4de54_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464899	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68|entrezgene/locuslink:9457(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:NP_001167010.1|refseq:NP_001167013.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16432466(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_5 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606	rogid:B0JdOqrjin6J5XTIC/0dXs6kRyw9606	rigid:QBD3Rqe4ftOZNMVpav4O3bmxrMk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5TD97	intact:EBI-16431359	intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357	-	psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464883	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68|entrezgene/locuslink:9457(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16432466(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:XLlpUR0/1u2hL1cfaiKN/5Hit8c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5TD97	uniprotkb:E9PJI6	intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464867	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68|entrezgene/locuslink:9457(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16432466(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:NqMj4Xt9CQGHwNDdHWPPY5E2sLI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P50221	uniprotkb:E9PJI6	intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464847	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16431349(see-also)|intact:EBI-16431361(see-also)|intact:EBI-16431371(see-also)|intact:EBI-16431381(see-also)|intact:EBI-16431391(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:w3JmXLU7ivVJwtXtIg0LThX7p7s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H2G9	uniprotkb:A0A0S2Z5G4	intact:EBI-2548012|intact:EBI-28986503|ensembl:ENSP00000327541|ensembl:ENSP00000356782|uniprotkb:O15298|uniprotkb:Q5T531|uniprotkb:Q5T533|uniprotkb:Q9GZX4	intact:EBI-16429704	psi-mi:go45_human(display_long)|uniprotkb:BLZF1(gene name)|psi-mi:BLZF1(display_short)|uniprotkb:JEM1(gene name synonym)|uniprotkb:Basic leucine zipper nuclear factor 1(gene name synonym)|uniprotkb:JEM-1(gene name synonym)|uniprotkb:p45 basic leucine-zipper nuclear factor(gene name synonym)	psi-mi:a0a0s2z5g4_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464831	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508394.1|ensembl:ENSG00000117475(gene)|ensembl:ENST00000329281(transcript)|ensembl:ENST00000367808(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR013183(Protein of unknown function DUF1721, fungi)|interpro:IPR027095|mint:Q9H2G9|reactome:R-HSA-162658|refseq:NP_003657.1|ensembl:ENSP00000327541|ensembl:ENST00000367807|ensembl:ENSP00000356781|ensembl:ENSP00000356782|refseq:NP_001307901.1|refseq:NP_001307902.1|entrezgene/locuslink:8548(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:XP_016878869.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16430992(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_7 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FqMAghbeSRbqLmtaKELM5JZ+H3s9606	rogid:B3CbJKL7yJtM34eeaCkXyqqisnQ9606	rigid:qKyzV4pxzBmU3GbxYqtRnVRMXy0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H2G9	intact:EBI-16431359	intact:EBI-2548012|intact:EBI-28986503|ensembl:ENSP00000327541|ensembl:ENSP00000356782|uniprotkb:O15298|uniprotkb:Q5T531|uniprotkb:Q5T533|uniprotkb:Q9GZX4	-	psi-mi:go45_human(display_long)|uniprotkb:BLZF1(gene name)|psi-mi:BLZF1(display_short)|uniprotkb:JEM1(gene name synonym)|uniprotkb:Basic leucine zipper nuclear factor 1(gene name synonym)|uniprotkb:JEM-1(gene name synonym)|uniprotkb:p45 basic leucine-zipper nuclear factor(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464815	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508394.1|ensembl:ENSG00000117475(gene)|ensembl:ENST00000329281(transcript)|ensembl:ENST00000367808(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR013183(Protein of unknown function DUF1721, fungi)|interpro:IPR027095|mint:Q9H2G9|reactome:R-HSA-162658|refseq:NP_003657.1|ensembl:ENSP00000327541|ensembl:ENST00000367807|ensembl:ENSP00000356781|ensembl:ENSP00000356782|refseq:NP_001307901.1|refseq:NP_001307902.1|entrezgene/locuslink:8548(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16430992(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FqMAghbeSRbqLmtaKELM5JZ+H3s9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:rkLtDvBC2R7FVyBI2um7pITV6mo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H2G9	uniprotkb:E9PJI6	intact:EBI-2548012|intact:EBI-28986503|ensembl:ENSP00000327541|ensembl:ENSP00000356782|uniprotkb:O15298|uniprotkb:Q5T531|uniprotkb:Q5T533|uniprotkb:Q9GZX4	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:go45_human(display_long)|uniprotkb:BLZF1(gene name)|psi-mi:BLZF1(display_short)|uniprotkb:JEM1(gene name synonym)|uniprotkb:Basic leucine zipper nuclear factor 1(gene name synonym)|uniprotkb:JEM-1(gene name synonym)|uniprotkb:p45 basic leucine-zipper nuclear factor(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464799	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508394.1|ensembl:ENSG00000117475(gene)|ensembl:ENST00000329281(transcript)|ensembl:ENST00000367808(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR013183(Protein of unknown function DUF1721, fungi)|interpro:IPR027095|mint:Q9H2G9|reactome:R-HSA-162658|refseq:NP_003657.1|ensembl:ENSP00000327541|ensembl:ENST00000367807|ensembl:ENSP00000356781|ensembl:ENSP00000356782|refseq:NP_001307901.1|refseq:NP_001307902.1|entrezgene/locuslink:8548(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16430992(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FqMAghbeSRbqLmtaKELM5JZ+H3s9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:g16T9KXTyDoEEMofKcOSVtZYRzU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TAP6	intact:EBI-16431359	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	-	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464781	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16430502(see-also)|intact:EBI-16430512(see-also)|intact:EBI-16430522(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:5e1vuQqfY8tSCso7BRxHnZ3FlfE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96QF0-7	intact:EBI-16431359	intact:EBI-11984839|ensembl:ENSP00000368092	-	psi-mi:q96qf0-7(display_long)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464746	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96QF0-7(isoform-parent)|intact:EBI-747844(isoform-parent)|ensembl:ENSG00000127328(gene)|ensembl:ENST00000378815(transcript)|entrezgene/locuslink:117177(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16429803(see-also)|intact:EBI-16429813(see-also)	isoform-comment:No experimental confirmation available.	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:AbUJj24KJUXc9MOj/FSx+ogmdfI9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:SEfKTmI2u6xaTU/4ViZu6iZ4zkE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:E9PJI6	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16464763	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16430502(see-also)|intact:EBI-16430512(see-also)|intact:EBI-16430522(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:EmSSswSXRWuu4+7OZJZA2pHyy5o	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16440472	intact:EBI-16431359	-	-	psi-mi:"ccsb orf id: 9576"(display_short)|psi-mi:EBI-16440472(display_long)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465540	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:57573(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16440474(see-also)|intact:EBI-16440484(see-also)|intact:EBI-16440494(see-also)|intact:EBI-16440534(see-also)|intact:EBI-16440544(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:x1KdEVhuKo5sZGVPBGE9eyTup9w9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:Kjl4ERNshVBdkbDxPPjV/XO6JZw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6P1W5	intact:EBI-16431359	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	-	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465519	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16440388(see-also)|intact:EBI-16440400(see-also)|intact:EBI-16440412(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:EpQQ8lh9BWVISt2FiFU1y/Y7Q0E	true	sufficient binding region:191-598	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6P1W5	uniprotkb:E9PJI6	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465498	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16440388(see-also)|intact:EBI-16440400(see-also)|intact:EBI-16440412(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:CwGh8gLo942BIljrssdHbGHV+Os	true	sufficient binding region:191-598	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:E9PJI6	intact:EBI-16439278	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465478	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16439329(see-also)|intact:EBI-16439339(see-also)|intact:EBI-16439349(see-also)|intact:EBI-16439359(see-also)|intact:EBI-16439369(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:ZJTXeJaR2kS/7ERGf1hIvT2q9A4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NF64	intact:EBI-16431359	intact:EBI-745786|uniprotkb:O94790|uniprotkb:Q0VGB4|uniprotkb:Q659A8|uniprotkb:Q6JKL5|uniprotkb:Q8WTX8|uniprotkb:Q96Q01|uniprotkb:Q9BQH7|uniprotkb:A4D2K7|uniprotkb:D3DVL1|intact:EBI-28976701|ensembl:ENSP00000311778|ensembl:ENSP00000414723	-	psi-mi:zmiz2_human(display_long)|uniprotkb:PIAS-like protein Zimp7(gene name synonym)|uniprotkb:ZMIZ2(gene name)|psi-mi:ZMIZ2(display_short)|uniprotkb:KIAA1886(gene name synonym)|uniprotkb:HRIHFB2007(orf name)|uniprotkb:ZIMP7(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465456	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_113637.3|refseq:NP_777589.2|ensembl:ENST00000265346|ensembl:ENSP00000265346|ensembl:ENSP00000311778|ensembl:ENST00000413916|ensembl:ENSP00000409648|ensembl:ENSP00000414723|refseq:NP_001287888.1|ensembl:ENSG00000122515(gene)|ensembl:ENST00000309315(transcript)|ensembl:ENST00000441627(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:XP_005249926.1|refseq:XP_005249929.1|entrezgene/locuslink:83637(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16439186(see-also)|intact:EBI-16439198(see-also)|intact:EBI-16439210(see-also)|intact:EBI-16439222(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:gkO57EyOLACt/8WYxFQbasiqRro9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:SywWL6wJwqVVQ7SwwBjdZ5K+3pU	true	sufficient binding region:479-920	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NF64	uniprotkb:E9PJI6	intact:EBI-745786|uniprotkb:O94790|uniprotkb:Q0VGB4|uniprotkb:Q659A8|uniprotkb:Q6JKL5|uniprotkb:Q8WTX8|uniprotkb:Q96Q01|uniprotkb:Q9BQH7|uniprotkb:A4D2K7|uniprotkb:D3DVL1|intact:EBI-28976701|ensembl:ENSP00000311778|ensembl:ENSP00000414723	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:zmiz2_human(display_long)|uniprotkb:PIAS-like protein Zimp7(gene name synonym)|uniprotkb:ZMIZ2(gene name)|psi-mi:ZMIZ2(display_short)|uniprotkb:KIAA1886(gene name synonym)|uniprotkb:HRIHFB2007(orf name)|uniprotkb:ZIMP7(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465434	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_113637.3|refseq:NP_777589.2|ensembl:ENST00000265346|ensembl:ENSP00000265346|ensembl:ENSP00000311778|ensembl:ENST00000413916|ensembl:ENSP00000409648|ensembl:ENSP00000414723|refseq:NP_001287888.1|ensembl:ENSG00000122515(gene)|ensembl:ENST00000309315(transcript)|ensembl:ENST00000441627(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:XP_005249926.1|refseq:XP_005249929.1|entrezgene/locuslink:83637(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16439186(see-also)|intact:EBI-16439198(see-also)|intact:EBI-16439210(see-also)|intact:EBI-16439222(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:gkO57EyOLACt/8WYxFQbasiqRro9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:TG6CNLvch64nTfTJklVSe4Eibyw	true	sufficient binding region:479-920	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HAN9	intact:EBI-16431359	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	-	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465416	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N|entrezgene/locuslink:64802(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16438880(see-also)|intact:EBI-16438890(see-also)|intact:EBI-16438900(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:/Ll38steqYxamkTP1HwueCufmMs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HAN9	uniprotkb:E9PJI6	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465398	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N|entrezgene/locuslink:64802(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16438880(see-also)|intact:EBI-16438890(see-also)|intact:EBI-16438900(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:2/Mk2hotNFGkedZ8W815tUibD9I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O60479	intact:EBI-16431359	intact:EBI-3908248|uniprotkb:B3KQL6|ensembl:ENSP00000389870	-	psi-mi:dlx3_human(display_long)|uniprotkb:DLX3(gene name)|psi-mi:DLX3(display_short)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465380	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005211.1|ensembl:ENSG00000064195(gene)|ensembl:ENST00000434704(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|rcsb pdb:4XRS|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0071895"(odontoblast differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|entrezgene/locuslink:1747(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16438402(see-also)|intact:EBI-16438412(see-also)|intact:EBI-16438422(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kU9aTRVuPjo/1OrEyWfyX4PMK9w9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:l+hOzs2ZxPgJo09uitNV34vNDRo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O60479	uniprotkb:E9PJI6	intact:EBI-3908248|uniprotkb:B3KQL6|ensembl:ENSP00000389870	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:dlx3_human(display_long)|uniprotkb:DLX3(gene name)|psi-mi:DLX3(display_short)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465362	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005211.1|ensembl:ENSG00000064195(gene)|ensembl:ENST00000434704(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|rcsb pdb:4XRS|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0071895"(odontoblast differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|entrezgene/locuslink:1747(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16438402(see-also)|intact:EBI-16438412(see-also)|intact:EBI-16438422(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kU9aTRVuPjo/1OrEyWfyX4PMK9w9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:vW37ddjzdRaaUlfle279LowFihQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08050	uniprotkb:A0A0S2Z5G4	intact:EBI-866480|uniprotkb:O43258|uniprotkb:O43259|uniprotkb:O43260|uniprotkb:Q4ZGG7|uniprotkb:Q9BRL2|ensembl:ENSP00000352901	intact:EBI-16429704	psi-mi:foxm1_human(display_long)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym)	psi-mi:a0a0s2z5g4_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465345	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068772.2|refseq:NP_973731.1|refseq:NP_973732.1|refseq:NP_001230017.1|refseq:NP_001230018.1|dip:DIP-36754N|ensembl:ENSG00000111206(gene)|ensembl:ENST00000359843(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|interpro:IPR042839|rcsb pdb:3G73|reactome:R-HSA-156711|reactome:R-HSA-69273|entrezgene/locuslink:2305(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:XP_016878869.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16437890(see-also)|intact:EBI-16437900(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_7 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u1jKIeT/XYuwT7KzYJbwdQXq7hM9606	rogid:B3CbJKL7yJtM34eeaCkXyqqisnQ9606	rigid:d0wWL85AFpJXEeXCyz4drdP3pVk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08050	uniprotkb:B4DE54	intact:EBI-866480|uniprotkb:O43258|uniprotkb:O43259|uniprotkb:O43260|uniprotkb:Q4ZGG7|uniprotkb:Q9BRL2|ensembl:ENSP00000352901	intact:EBI-16429313	psi-mi:foxm1_human(display_long)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym)	psi-mi:b4de54_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465328	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068772.2|refseq:NP_973731.1|refseq:NP_973732.1|refseq:NP_001230017.1|refseq:NP_001230018.1|dip:DIP-36754N|ensembl:ENSG00000111206(gene)|ensembl:ENST00000359843(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|interpro:IPR042839|rcsb pdb:3G73|reactome:R-HSA-156711|reactome:R-HSA-69273|entrezgene/locuslink:2305(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:NP_001167010.1|refseq:NP_001167013.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16437890(see-also)|intact:EBI-16437900(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_5 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u1jKIeT/XYuwT7KzYJbwdQXq7hM9606	rogid:B0JdOqrjin6J5XTIC/0dXs6kRyw9606	rigid:6k3W8FLqpAWGYWUM4YQyc8Rt96o	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08050	intact:EBI-16431359	intact:EBI-866480|uniprotkb:O43258|uniprotkb:O43259|uniprotkb:O43260|uniprotkb:Q4ZGG7|uniprotkb:Q9BRL2|ensembl:ENSP00000352901	-	psi-mi:foxm1_human(display_long)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465311	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068772.2|refseq:NP_973731.1|refseq:NP_973732.1|refseq:NP_001230017.1|refseq:NP_001230018.1|dip:DIP-36754N|ensembl:ENSG00000111206(gene)|ensembl:ENST00000359843(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|interpro:IPR042839|rcsb pdb:3G73|reactome:R-HSA-156711|reactome:R-HSA-69273|entrezgene/locuslink:2305(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16437890(see-also)|intact:EBI-16437900(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u1jKIeT/XYuwT7KzYJbwdQXq7hM9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:x+oS2iSCrlYC7unbRSx9XPqvai0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08050	uniprotkb:E9PJI6	intact:EBI-866480|uniprotkb:O43258|uniprotkb:O43259|uniprotkb:O43260|uniprotkb:Q4ZGG7|uniprotkb:Q9BRL2|ensembl:ENSP00000352901	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:foxm1_human(display_long)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465294	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068772.2|refseq:NP_973731.1|refseq:NP_973732.1|refseq:NP_001230017.1|refseq:NP_001230018.1|dip:DIP-36754N|ensembl:ENSG00000111206(gene)|ensembl:ENST00000359843(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|interpro:IPR042839|rcsb pdb:3G73|reactome:R-HSA-156711|reactome:R-HSA-69273|entrezgene/locuslink:2305(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16437890(see-also)|intact:EBI-16437900(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u1jKIeT/XYuwT7KzYJbwdQXq7hM9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:fxjclG4s540yKAPBau19zsQUuQs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O94842	intact:EBI-16431359	intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0	-	psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465275	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1|entrezgene/locuslink:9878(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16437830(see-also)|intact:EBI-16437840(see-also)|intact:EBI-16437850(see-also)|intact:EBI-16437860(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:bC3VjCDwZN0DROCXFITAFmHsHT4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O94842	uniprotkb:E9PJI6	intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465256	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1|entrezgene/locuslink:9878(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16437830(see-also)|intact:EBI-16437840(see-also)|intact:EBI-16437850(see-also)|intact:EBI-16437860(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:EiDWkcZNRU9NrZCdRoXvrag0oQo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14192	intact:EBI-16431359	intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15	-	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465237	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|entrezgene/locuslink:2274(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16437435(see-also)|intact:EBI-16437445(see-also)|intact:EBI-16437455(see-also)|intact:EBI-16437465(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:ArVONf/tPqxkF5FnpVL0oIF91CQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14192	uniprotkb:E9PJI6	intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465218	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|entrezgene/locuslink:2274(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16437435(see-also)|intact:EBI-16437445(see-also)|intact:EBI-16437455(see-also)|intact:EBI-16437465(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:z+XvVjtUKkSeByz5ElLk9kPZ0+s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P86478	uniprotkb:B4DE54	intact:EBI-12700196|ensembl:ENSP00000404281|uniprotkb:Q8N7V5	intact:EBI-16429313	psi-mi:pr20e_human(display_long)|uniprotkb:PRR20E(gene name)|psi-mi:PRR20E(display_short)	psi-mi:b4de54_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465201	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000234278(gene)|ensembl:ENST00000434815(transcript)|interpro:IPR031439|refseq:NP_001123876.1|refseq:NP_001123877.1|refseq:NP_001123878.1|refseq:NP_001123879.1|refseq:NP_940843.1|refseq:XP_016855016.1|entrezgene/locuslink:122183(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:NP_001167010.1|refseq:NP_001167013.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16436727(see-also)|intact:EBI-16436737(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_5 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2wZckiY1jYSxwgm2NPfkiJDu4Bw9606	rogid:B0JdOqrjin6J5XTIC/0dXs6kRyw9606	rigid:Fl8GdB3MsrIP3VDT6c8M093Yi1w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P86478	intact:EBI-16431359	intact:EBI-12700196|ensembl:ENSP00000404281|uniprotkb:Q8N7V5	-	psi-mi:pr20e_human(display_long)|uniprotkb:PRR20E(gene name)|psi-mi:PRR20E(display_short)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465184	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000234278(gene)|ensembl:ENST00000434815(transcript)|interpro:IPR031439|refseq:NP_001123876.1|refseq:NP_001123877.1|refseq:NP_001123878.1|refseq:NP_001123879.1|refseq:NP_940843.1|refseq:XP_016855016.1|entrezgene/locuslink:122183(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16436727(see-also)|intact:EBI-16436737(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2wZckiY1jYSxwgm2NPfkiJDu4Bw9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:ynnEBv5/cqBJh9ZTjBhXgiqcdgU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P86478	uniprotkb:E9PJI6	intact:EBI-12700196|ensembl:ENSP00000404281|uniprotkb:Q8N7V5	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:pr20e_human(display_long)|uniprotkb:PRR20E(gene name)|psi-mi:PRR20E(display_short)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465167	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000234278(gene)|ensembl:ENST00000434815(transcript)|interpro:IPR031439|refseq:NP_001123876.1|refseq:NP_001123877.1|refseq:NP_001123878.1|refseq:NP_001123879.1|refseq:NP_940843.1|refseq:XP_016855016.1|entrezgene/locuslink:122183(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16436727(see-also)|intact:EBI-16436737(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2wZckiY1jYSxwgm2NPfkiJDu4Bw9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:EOu8xuF/rc7WEpcjTwn869dUJUo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14627	uniprotkb:B4DE54	intact:EBI-10181162|uniprotkb:Q5JS20|uniprotkb:A1A513|ensembl:ENSP00000362613	intact:EBI-16429313	psi-mi:cdx4_human(display_long)|uniprotkb:CDX4(gene name)|psi-mi:CDX4(display_short)|uniprotkb:Caudal-type homeobox protein 4(gene name synonym)	psi-mi:b4de54_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465151	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005184.1|ensembl:ENSG00000131264(gene)|ensembl:ENST00000373514(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:1046(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:NP_001167010.1|refseq:NP_001167013.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16436717(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_5 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VjY+YbGRK+B4KOkI47ekRlWKivE9606	rogid:B0JdOqrjin6J5XTIC/0dXs6kRyw9606	rigid:wBqtU0sX2M51v2L91qJeOjKyA+4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14627	intact:EBI-16431359	intact:EBI-10181162|uniprotkb:Q5JS20|uniprotkb:A1A513|ensembl:ENSP00000362613	-	psi-mi:cdx4_human(display_long)|uniprotkb:CDX4(gene name)|psi-mi:CDX4(display_short)|uniprotkb:Caudal-type homeobox protein 4(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465135	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005184.1|ensembl:ENSG00000131264(gene)|ensembl:ENST00000373514(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:1046(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16436717(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VjY+YbGRK+B4KOkI47ekRlWKivE9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:sypmBy2E5FBONvXS3MKybukBaGI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14627	uniprotkb:E9PJI6	intact:EBI-10181162|uniprotkb:Q5JS20|uniprotkb:A1A513|ensembl:ENSP00000362613	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:cdx4_human(display_long)|uniprotkb:CDX4(gene name)|psi-mi:CDX4(display_short)|uniprotkb:Caudal-type homeobox protein 4(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005184.1|ensembl:ENSG00000131264(gene)|ensembl:ENST00000373514(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:1046(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16436717(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VjY+YbGRK+B4KOkI47ekRlWKivE9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:zuMpXlWCHKcb4unxVXA++V9+CTU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:E9PJI6	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465099	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16435668(see-also)|intact:EBI-16435678(see-also)|intact:EBI-16435688(see-also)|intact:EBI-16435698(see-also)|intact:EBI-16435708(see-also)	isoform-comment:No experimental confirmation available.	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:ifGScY2hev4/H5TLPtC+jPHfVWs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q02446	intact:EBI-16431359	intact:EBI-10198587|uniprotkb:Q32M52|uniprotkb:O60402|ensembl:ENSP00000222584	-	psi-mi:sp4_human(display_long)|uniprotkb:SP4(gene name)|psi-mi:SP4(display_short)|uniprotkb:SPR-1(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465080	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003103.2|refseq:NP_001313472.1|ensembl:ENSP00000222584|ensembl:ENSG00000105866(gene)|ensembl:ENST00000222584(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030453|interpro:IPR036236|entrezgene/locuslink:6671(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16435380(see-also)|intact:EBI-16435390(see-also)|intact:EBI-16435400(see-also)|intact:EBI-16435410(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:DK4Of4EpByHdtSsZb3eAiOlGFNY9606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:xHXnes3iVcxaHxP4otHDvAA+LIA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q02446	uniprotkb:E9PJI6	intact:EBI-10198587|uniprotkb:Q32M52|uniprotkb:O60402|ensembl:ENSP00000222584	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:sp4_human(display_long)|uniprotkb:SP4(gene name)|psi-mi:SP4(display_short)|uniprotkb:SPR-1(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465061	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003103.2|refseq:NP_001313472.1|ensembl:ENSP00000222584|ensembl:ENSG00000105866(gene)|ensembl:ENST00000222584(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030453|interpro:IPR036236|entrezgene/locuslink:6671(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16435380(see-also)|intact:EBI-16435390(see-also)|intact:EBI-16435400(see-also)|intact:EBI-16435410(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:DK4Of4EpByHdtSsZb3eAiOlGFNY9606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:Pd+yVoJd2HfoKZYFYSQ3L2gwAbg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08050-2	uniprotkb:A0A0S2Z5G4	intact:EBI-5237510|ensembl:ENSP00000354492	intact:EBI-16429704	psi-mi:q08050-2(display_long)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:FOXM1-b(isoform synonym)|uniprotkb:FoxM1B(isoform synonym)	psi-mi:a0a0s2z5g4_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465043	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-866480(isoform-parent)|ensembl:ENSG00000111206(gene)|ensembl:ENST00000361953(transcript)|entrezgene/locuslink:2305(identity)	interpro:IPR042343|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|refseq:XP_016878869.1|interpro:IPR018379|entrezgene/locuslink:54971(identity)	intact:EBI-16434868(see-also)|intact:EBI-16434905(see-also)|intact:EBI-16434915(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_7 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OErBT+uyHfgzDn6xI1OC8CATC049606	rogid:B3CbJKL7yJtM34eeaCkXyqqisnQ9606	rigid:nqkpWWaVhlIHhQqKQU6GvZxS/BM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08050-2	intact:EBI-16431359	intact:EBI-5237510|ensembl:ENSP00000354492	-	psi-mi:q08050-2(display_long)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:FOXM1-b(isoform synonym)|uniprotkb:FoxM1B(isoform synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465025	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-866480(isoform-parent)|ensembl:ENSG00000111206(gene)|ensembl:ENST00000361953(transcript)|entrezgene/locuslink:2305(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16434868(see-also)|intact:EBI-16434905(see-also)|intact:EBI-16434915(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OErBT+uyHfgzDn6xI1OC8CATC049606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:A//m5nsV5BKmHEWq5Cbky7XfVUQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12933	uniprotkb:E9PJI6	intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668	intact:EBI-16437731|ensembl:ENSP00000431812	psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym)	psi-mi:e9pji6_human(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465560	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000466197(transcript)|interpro:IPR042343|entrezgene/locuslink:54971(identity)	intact:EBI-16440634(see-also)|intact:EBI-16440644(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_2 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606	rogid:7cRt4IDU8Mehi7xlruMSFkll1zw9606	rigid:BBFTgcm3BI4aGb8Mk+DeygVLNXA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96LC9	uniprotkb:Q07817-2	intact:EBI-3919268|ensembl:ENSP00000346697|ensembl:ENSP00000380703|ensembl:ENSP00000453522|ensembl:ENSP00000453892|uniprotkb:Q7Z7D5|uniprotkb:Q9H7K7|uniprotkb:Q6NT30|uniprotkb:Q6P9F6|uniprotkb:Q6NT56|uniprotkb:Q7Z7D4|uniprotkb:Q2M396	intact:EBI-11091297|ensembl:ENSP00000365223|ensembl:ENSP00000411252	psi-mi:bmf_human(display_long)|uniprotkb:BMF(gene name)|psi-mi:BMF(display_short)	psi-mi:q07817-2(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Bcl-xS(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465594	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104081(gene)|ensembl:ENST00000354670(transcript)|ensembl:ENST00000397573(transcript)|ensembl:ENST00000561282(transcript)|ensembl:ENST00000561360(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016459"(myosin complex)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|interpro:IPR028192|reactome:R-HSA-111453|reactome:R-HSA-139910|refseq:NP_001003940.1|refseq:NP_001003942.1|refseq:NP_001003943.1|refseq:NP_277038.1|entrezgene/locuslink:90427(identity)	ensembl:ENSG00000171552(gene)|ensembl:ENST00000376055(transcript)|ensembl:ENST00000422920(transcript)|intact:EBI-78035(isoform-parent)|uniprotkb:Q07817-2(isoform-parent)|entrezgene/locuslink:598(identity)	intact:EBI-16431439(see-also)|intact:EBI-16431451(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BCL2L1_2 expression is provided in figureS2F."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2i6Tua07jZ3glxnc0ruMueU/JZw9606	rogid:NuCOMqr3shrrS2ILt09VPU3WROU9606	rigid:A1EKQaHkB59ikhPsYdlO4bbrFZk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12933	intact:EBI-16431359	intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668	-	psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym)	psi-mi:"ccsb isoform id: banp_3"(display_short)|psi-mi:EBI-16431359(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465577	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity)	entrezgene/locuslink:54971(identity)	intact:EBI-16440634(see-also)|intact:EBI-16440644(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BANP_3 expression is provided in figureS2G."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606	rogid:phgk1PxCdw0huTZTOM6vU3FYuC89606	rigid:zXWMX7GYzE+rYGqMrK8rI0iYhDw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q92934	uniprotkb:A0A0S2Z3D2	intact:EBI-700771|uniprotkb:O14803|uniprotkb:Q6FH21|ensembl:ENSP00000309103|ensembl:ENSP00000378040	intact:EBI-16431449	psi-mi:bad_human(display_long)|uniprotkb:Bcl-2-binding component 6(gene name synonym)|uniprotkb:Bcl-2-like protein 8(gene name synonym)|uniprotkb:BAD(gene name)|psi-mi:BAD(display_short)|uniprotkb:BBC6(gene name synonym)|uniprotkb:BCL2L8(gene name synonym)|uniprotkb:Bcl-xL/Bcl-2-associated death promoter(gene name synonym)|uniprotkb:Bcl2 antagonist of cell death(gene name synonym)	psi-mi:a0a0s2z3d2_human(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:Bcl-2-like protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465627	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004313.1|refseq:NP_116784.1|dip:DIP-29184N|ensembl:ENSG00000002330(gene)|ensembl:ENST00000309032(transcript)|ensembl:ENST00000394532(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008289"(lipid binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033574"(response to testosterone)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046031"(ADP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0071247"(cellular response to chromate)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901423"(response to benzene)|go:"GO:1902220"(positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1904710"(positive regulation of granulosa cell apoptotic process)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR018868|mint:Q92934|rcsb pdb:1G5J|reactome:R-HSA-111447|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-198323|reactome:R-HSA-5674400|entrezgene/locuslink:572(identity)	go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR026298|interpro:IPR020731|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR013279(Apoptosis regulator, Bcl-X)|interpro:IPR020728|interpro:IPR036834|entrezgene/locuslink:598(identity)	intact:EBI-16433819(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BCL2L1_3 expression is provided in figureS2F."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2c2kSu+3ZHnx458SDbvIcdGV4PA9606	rogid:3qwkOrNcTdGiBthNQHV3qpVD13s9606	rigid:WOzWuD/uK7QBBg8FJwVGoYz8Z1A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q92934	uniprotkb:Q07817-2	intact:EBI-700771|uniprotkb:O14803|uniprotkb:Q6FH21|ensembl:ENSP00000309103|ensembl:ENSP00000378040	intact:EBI-11091297|ensembl:ENSP00000365223|ensembl:ENSP00000411252	psi-mi:bad_human(display_long)|uniprotkb:Bcl-2-binding component 6(gene name synonym)|uniprotkb:Bcl-2-like protein 8(gene name synonym)|uniprotkb:BAD(gene name)|psi-mi:BAD(display_short)|uniprotkb:BBC6(gene name synonym)|uniprotkb:BCL2L8(gene name synonym)|uniprotkb:Bcl-xL/Bcl-2-associated death promoter(gene name synonym)|uniprotkb:Bcl2 antagonist of cell death(gene name synonym)	psi-mi:q07817-2(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Bcl-xS(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465611	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004313.1|refseq:NP_116784.1|dip:DIP-29184N|ensembl:ENSG00000002330(gene)|ensembl:ENST00000309032(transcript)|ensembl:ENST00000394532(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008289"(lipid binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033574"(response to testosterone)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046031"(ADP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0071247"(cellular response to chromate)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901423"(response to benzene)|go:"GO:1902220"(positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1904710"(positive regulation of granulosa cell apoptotic process)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR018868|mint:Q92934|rcsb pdb:1G5J|reactome:R-HSA-111447|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-198323|reactome:R-HSA-5674400|entrezgene/locuslink:572(identity)	ensembl:ENSG00000171552(gene)|ensembl:ENST00000376055(transcript)|ensembl:ENST00000422920(transcript)|intact:EBI-78035(isoform-parent)|uniprotkb:Q07817-2(isoform-parent)|entrezgene/locuslink:598(identity)	intact:EBI-16433819(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BCL2L1_2 expression is provided in figureS2F."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2c2kSu+3ZHnx458SDbvIcdGV4PA9606	rogid:NuCOMqr3shrrS2ILt09VPU3WROU9606	rigid:2NTFzffv7sWgyu+aMlbuPQeksys	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WWW0-2	uniprotkb:A0A0S2Z4Q5	intact:EBI-960502|ensembl:ENSP00000462576	intact:EBI-16465731	psi-mi:q8www0-2(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:RASSF5(gene name)|psi-mi:RASSF5(display_short)|uniprotkb:NORE1(gene name synonym)|uniprotkb:RAPL(gene name synonym)|uniprotkb:New ras effector 1(gene name synonym)|uniprotkb:Regulator for cell adhesion and polarization enriched in lymphoid tissues(gene name synonym)	psi-mi:a0a0s2z4q5_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465752	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-367390(q8www0_human)|ensembl:ENSG00000266094(gene)|ensembl:ENST00000577571(transcript)|uniprotkb:Q8WWW0-2(isoform-parent)|entrezgene/locuslink:83593(identity)	entrezgene/locuslink:8945(identity)	intact:EBI-16430021(see-also)|intact:EBI-16430031(see-also)	isoform-comment:Initiator Met-1 is removed. Contains a N-acetylthreonine at position 2.	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_2 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:zcc13rWLmCPQVfU4D6bvIiAnIbc9606	rogid:/y4SRSYmWMFGSM+YV0H4YbmUGxY9606	rigid:OYpdezIR2SdeuLfywqlB4Y8InAk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9C026	uniprotkb:A0A0S2Z4Q5	intact:EBI-720828|ensembl:ENSP00000298355|uniprotkb:Q92557|uniprotkb:Q96D24|uniprotkb:Q96NI4|uniprotkb:Q9C025|uniprotkb:Q9C027|uniprotkb:D3DSB7|uniprotkb:D3DSB8	intact:EBI-16465731	psi-mi:trim9_human(display_long)|uniprotkb:RING finger protein 91(gene name synonym)|uniprotkb:TRIM9(gene name)|psi-mi:TRIM9(display_short)|uniprotkb:KIAA0282(gene name synonym)|uniprotkb:RNF91(gene name synonym)|uniprotkb:Tripartite motif-containing protein 9(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM9(gene name synonym)	psi-mi:a0a0s2z4q5_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465786	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100505(gene)|ensembl:ENST00000298355(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR036116|interpro:IPR043136|rcsb pdb:2DB8|rcsb pdb:7B2S|reactome:R-HSA-983168|refseq:XP_011534691.1|refseq:NP_055978.4|refseq:NP_443210.1|refseq:XP_016876434.1|entrezgene/locuslink:114088(identity)	entrezgene/locuslink:8945(identity)	intact:EBI-16431493(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_2 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:cWf6NobHVvKBKNqclJsLeoJKfMw9606	rogid:/y4SRSYmWMFGSM+YV0H4YbmUGxY9606	rigid:umZzOXc+BSoh3FXyg6cx6pfeIZ8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00444	uniprotkb:A0A0S2Z4Q5	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	intact:EBI-16465731	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:a0a0s2z4q5_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465802	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|entrezgene/locuslink:10733(identity)	entrezgene/locuslink:8945(identity)	intact:EBI-16432676(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_2 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	rogid:/y4SRSYmWMFGSM+YV0H4YbmUGxY9606	rigid:OwfhuvELWC1WlvvffUkpRIc4WXA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00444	uniprotkb:A0A0S2Z507	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	intact:EBI-16429247	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:a0a0s2z507_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465818	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|entrezgene/locuslink:10733(identity)	go:"GO:0046983"(protein dimerization activity)|interpro:IPR021977|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036047|interpro:IPR036322|entrezgene/locuslink:8945(identity)	intact:EBI-16432676(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_3 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	rogid:MFv+nq3XA7DR61lk2x4jN8sKfCw9606	rigid:HT4+0clf0EvS6FwXkeFXn0WudT4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00444	uniprotkb:B7Z3H4	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	intact:EBI-16429269|ensembl:ENSP00000377088	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:b7z3h4_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)|uniprotkb:hCG_1811016(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465834	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|entrezgene/locuslink:10733(identity)	ensembl:ENSG00000166167(gene)|ensembl:ENST00000393441(transcript)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|refseq:NP_001243785.1|entrezgene/locuslink:8945(identity)	intact:EBI-16432676(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_4 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	rogid:IbM+YU1ikaWXnOc33Set3iX0O+Q9606	rigid:augjcqPlx9PF/mNB8QjLoBzzObY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P18848	uniprotkb:A0A0S2Z4Q5	intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3	intact:EBI-16465731	psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym)	psi-mi:a0a0s2z4q5_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465850	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N|entrezgene/locuslink:468(identity)	entrezgene/locuslink:8945(identity)	intact:EBI-16434975(see-also)|intact:EBI-16434985(see-also)	crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution  removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists."	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_2 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2UolKWXxKFddysaOo70/U/1pI5k9606	rogid:/y4SRSYmWMFGSM+YV0H4YbmUGxY9606	rigid:WVl3z4HbM4ROl58XwRA3gRAw7m4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9C026-5	uniprotkb:A0A0S2Z4Q5	intact:EBI-16437499|ensembl:ENSP00000353561	intact:EBI-16465731	psi-mi:q9c026-5(display_long)|uniprotkb:RING finger protein 91(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM9(gene name synonym)|uniprotkb:Tripartite motif-containing protein 9(gene name synonym)|uniprotkb:TRIM9(gene name)|psi-mi:TRIM9(display_short)|uniprotkb:KIAA0282(gene name synonym)|uniprotkb:RNF91(gene name synonym)	psi-mi:a0a0s2z4q5_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465867	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100505(gene)|ensembl:ENST00000360392(transcript)|intact:EBI-720828(isoform-parent)|uniprotkb:Q9C026-5(isoform-parent)|entrezgene/locuslink:114088(identity)	entrezgene/locuslink:8945(identity)	intact:EBI-16437506(see-also)|intact:EBI-16437516(see-also)|intact:EBI-16437526(see-also)	isoform-comment:May be due to intron retention.	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_2 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:6t1br4sRAyAn+kB91xNFnS/ZhVc9606	rogid:/y4SRSYmWMFGSM+YV0H4YbmUGxY9606	rigid:ie0AUaZRWYs/blB5M4VLgTC3rU0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P18848	uniprotkb:A0A0S2Z4Q5	intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3	intact:EBI-16465731	psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym)	psi-mi:a0a0s2z4q5_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465885	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N|entrezgene/locuslink:468(identity)	entrezgene/locuslink:8945(identity)	intact:EBI-16437999(see-also)|intact:EBI-16438009(see-also)|intact:EBI-16438019(see-also)	crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution  removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists."	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_2 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2UolKWXxKFddysaOo70/U/1pI5k9606	rogid:/y4SRSYmWMFGSM+YV0H4YbmUGxY9606	rigid:WVl3z4HbM4ROl58XwRA3gRAw7m4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:A0A0S2Z5Z3	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-16435510	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:a0a0s2z5z3_human(display_long)|uniprotkb:C6orf142(gene name)|psi-mi:C6orf142(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465903	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	interpro:IPR029331|entrezgene/locuslink:90523(identity)	intact:EBI-16435748(see-also)	isoform-comment:No experimental confirmation available.	-	comment:"Evidence for isoform CCSB isoform ID: C6orf142_6 expression is provided in figureS2A."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:PfQUKaz+GBfRD1ufYrtnB7serb89606	rigid:AqbexUScQYtjqBs/sb4BSv3omcY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O76003	uniprotkb:A0A0S2Z341	intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2	intact:EBI-16465919	psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym)	psi-mi:a0a0s2z341_human(display_long)|uniprotkb:CA9(gene name)|psi-mi:CA9(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465922	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N|entrezgene/locuslink:10539(identity)	go:"GO:0004089"(carbonate dehydratase activity)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR018338|interpro:IPR018429|interpro:IPR023561|interpro:IPR036398|entrezgene/locuslink:768(identity)	intact:EBI-16436308(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606	rogid:EghTBTX6++a4s0rZn43UQmLE2hY9606	rigid:nGdFzILF2SgFRTtJ1UCju3LACAs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P20807-4	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-11532021|ensembl:ENSP00000380384	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:p20807-4(display_long)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465938	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	intact:EBI-5655000(isoform-parent)|uniprotkb:P20807-4(isoform-parent)|ensembl:ENSG00000092529(gene)|ensembl:ENST00000397200(transcript)|entrezgene/locuslink:825(identity)	intact:EBI-16430534(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:6TrGg2jigHr0xYLsxBNCLjAl3J89606	rigid:zbx/WzOE/aQ1Pn576idO9YXdrRI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75410-7	uniprotkb:A0A0S2Z4Q5	intact:EBI-12007872|ensembl:ENSP00000428706	intact:EBI-16465731	psi-mi:o75410-7(display_long)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:KIAA1103(gene name synonym)|uniprotkb:Taxin-1(gene name synonym)	psi-mi:a0a0s2z4q5_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465734	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-624237(isoform-parent)|ensembl:ENSG00000147526(gene)|ensembl:ENST00000518415(transcript)|uniprotkb:O75410-7(isoform-parent)|entrezgene/locuslink:6867(identity)	entrezgene/locuslink:8945(identity)	intact:EBI-16429237(see-also)|intact:EBI-16429259(see-also)|intact:EBI-16429286(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_2 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:l8Qbl9ca/hqZkBKqQ2v6GjaAEgk9606	rogid:/y4SRSYmWMFGSM+YV0H4YbmUGxY9606	rigid:Y1E2GXW8zC78AjPtjK2jUX20nuw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96IJ6	uniprotkb:A0A0S2Z3I5	intact:EBI-750953|uniprotkb:A6NJ74|uniprotkb:A8K3Q6|uniprotkb:Q53GI0|uniprotkb:Q9NWC3|uniprotkb:Q9Y5P5|uniprotkb:B3KMT4|ensembl:ENSP00000315925|ensembl:ENSP00000340760|ensembl:ENSP00000350949|ensembl:ENSP00000363016|ensembl:ENSP00000478700|ensembl:ENSP00000506941	intact:EBI-16465708	psi-mi:gmppa_human(display_long)|uniprotkb:GMPPA(gene name)|psi-mi:GMPPA(display_short)|uniprotkb:GTP-mannose-1-phosphate guanylyltransferase alpha(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase A(gene name synonym)	psi-mi:a0a0s2z3i5_human(display_long)|uniprotkb:BTC(gene name)|psi-mi:BTC(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465715	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037467.2|refseq:NP_995319.1|refseq:XP_005246543.1|refseq:XP_016859398.1|refseq:XP_016859399.1|refseq:XP_016859400.1|ensembl:ENSG00000144591(gene)|ensembl:ENST00000313597(transcript)|ensembl:ENST00000341142(transcript)|ensembl:ENST00000358215(transcript)|ensembl:ENST00000373908(transcript)|ensembl:ENST00000622191(transcript)|ensembl:ENST00000683946(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|mint:Q96IJ6|rcsb pdb:7D72|rcsb pdb:7D73|rcsb pdb:7D74|reactome:R-HSA-446205|entrezgene/locuslink:29926(identity)	go:"GO:0005154"(epidermal growth factor receptor binding)|interpro:IPR015497(Epidermal growth factor receptor ligand)|refseq:NP_001303892.1|entrezgene/locuslink:685(identity)	intact:EBI-16434559(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ASWzJoQB8W+e2OKYEenXpUJxflI9606	rogid:e2V7UBBKhvGhrrNRn8H+4nwIV+o9606	rigid:eXcFmDhYsdGjbCuVNz60c7s5HcE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	uniprotkb:Q07817-2	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	intact:EBI-11091297|ensembl:ENSP00000365223|ensembl:ENSP00000411252	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:q07817-2(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Bcl-xS(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465692	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	ensembl:ENSG00000171552(gene)|ensembl:ENST00000376055(transcript)|ensembl:ENST00000422920(transcript)|intact:EBI-78035(isoform-parent)|uniprotkb:Q07817-2(isoform-parent)|entrezgene/locuslink:598(identity)	intact:EBI-16436941(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BCL2L1_2 expression is provided in figureS2F."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:NuCOMqr3shrrS2ILt09VPU3WROU9606	rigid:uX21Cd9Z84JOwEn7Tevp8AddFM0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	uniprotkb:Q07817	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	intact:EBI-78035|intact:EBI-28978054|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|uniprotkb:Q5TE65|uniprotkb:Q92976|uniprotkb:Q5CZ89|uniprotkb:E1P5L6	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:b2cl1_human(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465676	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	refseq:NP_001182.1|refseq:NP_612815.1|ensembl:ENSG00000171552(gene)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)|ensembl:ENST00000678563(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009566"(fertilization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034097"(response to cytokine)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071839"(apoptotic process in bone marrow cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR004725(Apoptosis regulator Bcl-X protein)|interpro:IPR013279(Apoptosis regulator, Bcl-X)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR020731|interpro:IPR026298|interpro:IPR036834|mint:Q07817|rcsb pdb:1BXL|rcsb pdb:1G5J|rcsb pdb:1LXL|rcsb pdb:1MAZ|rcsb pdb:1R2D|rcsb pdb:1R2E|rcsb pdb:1R2G|rcsb pdb:1R2H|rcsb pdb:1R2I|rcsb pdb:1YSG|rcsb pdb:1YSI|rcsb pdb:1YSN|rcsb pdb:2B48|rcsb pdb:2LP8|rcsb pdb:2LPC|rcsb pdb:2M03|rcsb pdb:2M04|rcsb pdb:2ME8|rcsb pdb:2ME9|rcsb pdb:2MEJ|rcsb pdb:2O1Y|rcsb pdb:2O2M|rcsb pdb:2O2N|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:2YJ1|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:2YXJ|rcsb pdb:3CVA|rcsb pdb:3FDL|rcsb pdb:3FDM|rcsb pdb:3INQ|rcsb pdb:3IO8|rcsb pdb:3PL7|rcsb pdb:3QKD|rcsb pdb:3R85|rcsb pdb:6IJQ|rcsb pdb:6LHD|rcsb pdb:6O0K|rcsb pdb:6O0L|rcsb pdb:6O0M|rcsb pdb:6O0O|rcsb pdb:6O0P|rcsb pdb:6RNU|rcsb pdb:6ST2|rcsb pdb:6UVC|rcsb pdb:6UVD|rcsb pdb:6UVE|rcsb pdb:6UVF|rcsb pdb:6UVG|rcsb pdb:6UVH|rcsb pdb:6VWC|rcsb pdb:6X7I|rcsb pdb:6YLI|rcsb pdb:6ZHC|rcsb pdb:7CA4|rcsb pdb:7JGV|rcsb pdb:7JGW|rcsb pdb:7LH7|reactome:R-HSA-111453|reactome:R-HSA-6785807|reactome:R-HSA-844455|reactome:R-HSA-9648002|reactome:R-HSA-9702518|rcsb pdb:3SP7|rcsb pdb:3SPF|rcsb pdb:3WIZ|rcsb pdb:3ZK6|rcsb pdb:3ZLN|rcsb pdb:6F46|rcsb pdb:6HJL|rcsb pdb:3ZLO|rcsb pdb:3ZLR|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4AQ3|rcsb pdb:4BPK|rcsb pdb:4C52|rcsb pdb:4C5D|rcsb pdb:4CIN|rcsb pdb:4EHR|rcsb pdb:4HNJ|rcsb pdb:4IEH|rcsb pdb:4PPI|rcsb pdb:4QVE|rcsb pdb:4QVF|rcsb pdb:4QVX|rcsb pdb:4TUH|rcsb pdb:4Z9V|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5B1Z|rcsb pdb:5C3G|rcsb pdb:5FMJ|rcsb pdb:5FMK|rcsb pdb:5VAY|rcsb pdb:5VX3|rcsb pdb:6BF2|rcsb pdb:6DCN|rcsb pdb:6DCO|ensembl:ENSP00000365223|ensembl:ENSP00000365230|ensembl:ENSP00000390760|ensembl:ENST00000376055|ensembl:ENST00000422920|ensembl:ENSP00000411252|ensembl:ENSP00000401173|ensembl:ENSP00000389688|ensembl:ENSP00000395545|ensembl:ENSP00000503725|ensembl:ENSP00000504536|ensembl:ENSP00000504387|ensembl:ENSP00000504237|ensembl:ENSP00000302564|refseq:NP_001304848.1|refseq:NP_001304849.1|refseq:NP_001304850.1|refseq:NP_001309168.1|refseq:NP_001309169.1|refseq:NP_001309171.1|refseq:XP_011527266.1|refseq:XP_016883482.1|dip:DIP-30916N|entrezgene/locuslink:598(identity)	intact:EBI-16436941(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BCL2L1_1 expression is provided in figureS2F."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606	rigid:349mrjMS6yPo8eQPu2qSoZiPagM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13323	uniprotkb:Q07817-2	intact:EBI-700794|uniprotkb:Q16582|uniprotkb:Q6FH93|ensembl:ENSP00000216115	intact:EBI-11091297|ensembl:ENSP00000365223|ensembl:ENSP00000411252	psi-mi:bik_human(display_long)|uniprotkb:Apoptosis inducer NBK(gene name synonym)|uniprotkb:BP4(gene name synonym)|uniprotkb:BIP1(gene name synonym)|uniprotkb:BIK(gene name)|psi-mi:BIK(display_short)|uniprotkb:NBK(gene name synonym)	psi-mi:q07817-2(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Bcl-xS(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465659	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188.1|dip:DIP-928N|ensembl:ENSG00000100290(gene)|ensembl:ENST00000216115(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0008584"(male gonad development)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|interpro:IPR020728|interpro:IPR024579|rcsb pdb:2IPE|entrezgene/locuslink:638(identity)	ensembl:ENSG00000171552(gene)|ensembl:ENST00000376055(transcript)|ensembl:ENST00000422920(transcript)|intact:EBI-78035(isoform-parent)|uniprotkb:Q07817-2(isoform-parent)|entrezgene/locuslink:598(identity)	intact:EBI-16433829(see-also)|intact:EBI-16433839(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: BCL2L1_2 expression is provided in figureS2F."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M34Yl66KzkhNSq7e3WKQMb6WDqU9606	rogid:NuCOMqr3shrrS2ILt09VPU3WROU9606	rigid:9pFUlsrK0+X5qdQyZNT821PTDmM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WWW0-2	uniprotkb:B7Z3H4	intact:EBI-960502|ensembl:ENSP00000462576	intact:EBI-16429269|ensembl:ENSP00000377088	psi-mi:q8www0-2(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:RASSF5(gene name)|psi-mi:RASSF5(display_short)|uniprotkb:NORE1(gene name synonym)|uniprotkb:RAPL(gene name synonym)|uniprotkb:New ras effector 1(gene name synonym)|uniprotkb:Regulator for cell adhesion and polarization enriched in lymphoid tissues(gene name synonym)	psi-mi:b7z3h4_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)|uniprotkb:hCG_1811016(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465769	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-367390(q8www0_human)|ensembl:ENSG00000266094(gene)|ensembl:ENST00000577571(transcript)|uniprotkb:Q8WWW0-2(isoform-parent)|entrezgene/locuslink:83593(identity)	ensembl:ENSG00000166167(gene)|ensembl:ENST00000393441(transcript)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|refseq:NP_001243785.1|entrezgene/locuslink:8945(identity)	intact:EBI-16430021(see-also)|intact:EBI-16430031(see-also)	isoform-comment:Initiator Met-1 is removed. Contains a N-acetylthreonine at position 2.	-	comment:"Evidence for isoform CCSB isoform ID: BTRC_4 expression is provided in figure2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:zcc13rWLmCPQVfU4D6bvIiAnIbc9606	rogid:IbM+YU1ikaWXnOc33Set3iX0O+Q9606	rigid:Ldmv65EjGabKFtCADqD1QeRZWZA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9C040	uniprotkb:A0A0S2Z535	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	intact:EBI-16466123	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:a0a0s2z535_human(display_long)|uniprotkb:CDK20(gene name)|psi-mi:CDK20(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466134	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:23321(identity)	go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|entrezgene/locuslink:23552(identity)	intact:EBI-16432961(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	rogid:bNr8fCnUh6JVd1nweyJnl1vRq1U9606	rigid:RAHCkB0+YYLFoW7ICeJTbEGiVtk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9C040	uniprotkb:Q8IZL9-5	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	intact:EBI-16466096|ensembl:ENSP00000365043	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:q8izl9-5(display_long)|uniprotkb:CDK-activating kinase p42(gene name synonym)|uniprotkb:Cell cycle-related kinase(gene name synonym)|uniprotkb:Cell division protein kinase 20(gene name synonym)|uniprotkb:Cyclin-dependent protein kinase H(gene name synonym)|uniprotkb:Cyclin-kinase-activating kinase p42(gene name synonym)|uniprotkb:CDK20(gene name)|psi-mi:CDK20(display_short)|uniprotkb:CCRK(gene name synonym)|uniprotkb:CDCH(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466104	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:23321(identity)	intact:EBI-6128565(isoform-parent)|ensembl:ENSG00000156345(gene)|ensembl:ENST00000375883(transcript)|entrezgene/locuslink:23552(identity)	intact:EBI-16432961(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	rogid:8/Rfk69ifNEUfBSw6ZmO3XtVpR49606	rigid:ln15B++HH1aVtBp2Icj2CUXlMPA	true	-	sufficient binding region:1-284	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9C040	uniprotkb:Q8IZL9-3	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	intact:EBI-16466072|ensembl:ENSP00000474485	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:q8izl9-3(display_long)|uniprotkb:CDK-activating kinase p42(gene name synonym)|uniprotkb:Cell cycle-related kinase(gene name synonym)|uniprotkb:Cell division protein kinase 20(gene name synonym)|uniprotkb:Cyclin-dependent protein kinase H(gene name synonym)|uniprotkb:Cyclin-kinase-activating kinase p42(gene name synonym)|uniprotkb:CDK20(gene name)|psi-mi:CDK20(display_short)|uniprotkb:CCRK(gene name synonym)|uniprotkb:CDCH(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466080	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:23321(identity)	intact:EBI-6128565(isoform-parent)|ensembl:ENSG00000156345(gene)|ensembl:ENST00000605159(transcript)|entrezgene/locuslink:23552(identity)	intact:EBI-16432961(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	rogid:mzVgLqbO3Gx5NNkSScj/30Q6PkI9606	rigid:jHbYac9KDRaDIeBQjd6t/DiRLl0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q8TCZ2	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-2824782|uniprotkb:B3KWG2|uniprotkb:E7EMK5|uniprotkb:A8K2D5|uniprotkb:Q9BQG9|uniprotkb:Q8TCZ0|uniprotkb:Q8TCZ1|uniprotkb:Q8TAW2|uniprotkb:A8K5R0|ensembl:ENSP00000359403|uniprotkb:B4DDL7|uniprotkb:E9PD27	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:c99l2_human(display_long)|uniprotkb:CD99L2(gene name)|psi-mi:CD99L2(display_short)|uniprotkb:MIC2L1(gene name synonym)|uniprotkb:MIC2-like protein 1(gene name synonym)|uniprotkb:UNQ1964/PRO4486(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466056	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:XP_011529504.1|ensembl:ENSG00000102181(gene)|ensembl:ENST00000370377(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|interpro:IPR022078|reactome:R-HSA-202733|refseq:NP_001171737.1|refseq:NP_001229543.1|refseq:NP_113650.2|refseq:NP_604394.1|refseq:NP_604395.1|entrezgene/locuslink:83692(identity)	intact:EBI-16438188(see-also)	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:cOdUpR8H6oxHn9UfccggMMm1Z2Q9606	rigid:LBAu+8JribIhl/WWeNW/Nntefpw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BRI3	uniprotkb:Q8TCZ2	intact:EBI-8644112|ensembl:ENSP00000363396|intact:MINT-8163383|uniprotkb:Q71RC8	intact:EBI-2824782|uniprotkb:B3KWG2|uniprotkb:E7EMK5|uniprotkb:A8K2D5|uniprotkb:Q9BQG9|uniprotkb:Q8TCZ0|uniprotkb:Q8TCZ1|uniprotkb:Q8TAW2|uniprotkb:A8K5R0|ensembl:ENSP00000359403|uniprotkb:B4DDL7|uniprotkb:E9PD27	psi-mi:znt2_human(display_long)|uniprotkb:SLC30A2(gene name)|psi-mi:SLC30A2(display_short)|uniprotkb:Solute carrier family 30 member 2(gene name synonym)|uniprotkb:ZNT2(gene name synonym)	psi-mi:c99l2_human(display_long)|uniprotkb:CD99L2(gene name)|psi-mi:CD99L2(display_short)|uniprotkb:MIC2L1(gene name synonym)|uniprotkb:MIC2-like protein 1(gene name synonym)|uniprotkb:UNQ1964/PRO4486(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466040	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000158014(gene)|ensembl:ENST00000374278(transcript)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0061090"(positive regulation of sequestering of zinc ion)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-HSA-435368|refseq:NP_001004434.1|refseq:NP_115902.1|entrezgene/locuslink:7780(identity)	refseq:XP_011529504.1|ensembl:ENSG00000102181(gene)|ensembl:ENST00000370377(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|interpro:IPR022078|reactome:R-HSA-202733|refseq:NP_001171737.1|refseq:NP_001229543.1|refseq:NP_113650.2|refseq:NP_604394.1|refseq:NP_604395.1|entrezgene/locuslink:83692(identity)	intact:EBI-16434931(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E8UyE30F1s0H0A4awhgqZ6MIEuU9606	rogid:cOdUpR8H6oxHn9UfccggMMm1Z2Q9606	rigid:tf6rjO6yp1ZvueG+S880wOt+Y/0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:A0A0S2Z5R8	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-16434925	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:a0a0s2z5r8_human(display_long)|uniprotkb:CD99L2(gene name)|psi-mi:CD99L2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466024	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	go:"GO:0016021"(integral component of membrane)|interpro:IPR022078|entrezgene/locuslink:83692(identity)	intact:EBI-16434057(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:h2nTTqEOlXrDcArFAaSjcDJDju49606	rigid:brRCihx/XTqw59QsNiqCMTTKe+E	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:A0A0S2Z5R8	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-16434925	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:a0a0s2z5r8_human(display_long)|uniprotkb:CD99L2(gene name)|psi-mi:CD99L2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466008	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	go:"GO:0016021"(integral component of membrane)|interpro:IPR022078|entrezgene/locuslink:83692(identity)	intact:EBI-16432790(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:h2nTTqEOlXrDcArFAaSjcDJDju49606	rigid:P98P5AiwDt/mdctHeYlXN1mHfz8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0-2	uniprotkb:A0A0S2Z5R8	intact:EBI-10173939|ensembl:ENSP00000257468	intact:EBI-16434925	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:a0a0s2z5r8_human(display_long)|uniprotkb:CD99L2(gene name)|psi-mi:CD99L2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465992	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	go:"GO:0016021"(integral component of membrane)|interpro:IPR022078|entrezgene/locuslink:83692(identity)	intact:EBI-16431106(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rogid:h2nTTqEOlXrDcArFAaSjcDJDju49606	rigid:Frs+yUg7yJ0yHSxIQOC/JWh9uZ0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P42575	uniprotkb:A0A0S2Z3I0	intact:EBI-520342|ensembl:ENSP00000312664|uniprotkb:P42576|uniprotkb:D3DXD6|uniprotkb:Q59F21|uniprotkb:Q7KZL6|uniprotkb:Q86UJ3|uniprotkb:Q9BUP7|uniprotkb:Q9BZK9|uniprotkb:A8K5F9|uniprotkb:E9PDN0|uniprotkb:Q9BZL0	intact:EBI-16465973	psi-mi:casp2_human(display_long)|uniprotkb:Protease ICH-1(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 2(gene name synonym)|uniprotkb:CASP2(gene name)|psi-mi:CASP2(display_short)|uniprotkb:ICH1(gene name synonym)|uniprotkb:NEDD2(gene name synonym)	psi-mi:a0a0s2z3i0_human(display_long)|uniprotkb:CASP2(gene name)|psi-mi:CASP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465976	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106144(gene)|ensembl:ENST00000310447(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0003407"(neural retina development)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR035702|rcsb pdb:1PYO|rcsb pdb:2P2C|rcsb pdb:3R5J|rcsb pdb:3R6G|rcsb pdb:3R6L|rcsb pdb:3R7B|rcsb pdb:3R7N|refseq:NP_001215.1|refseq:NP_116764.2|refseq:NP_116765.2|rcsb pdb:3R7S|rcsb pdb:3RJM|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y8B|rcsb pdb:6Y8D|reactome:R-HSA-168638|reactome:R-HSA-205025|reactome:R-HSA-6803207|entrezgene/locuslink:835(identity)	go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|entrezgene/locuslink:835(identity)	intact:EBI-16433486(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3WFvmDoYbW3J84Yd9RVGAOcR8ig9606	rogid:ckpVZUI1KmwvIG8BejUQJBKJ5Zk9606	rigid:wo+/Z9AOwRB5k6/5zbJn1XZZ0rc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P20807-2	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-16433991|ensembl:ENSP00000183936	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:p20807-2(display_long)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:NCL1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16465954	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	intact:EBI-5655000(isoform-parent)|ensembl:ENSG00000092529(gene)|ensembl:ENST00000349748(transcript)|entrezgene/locuslink:825(identity)	intact:EBI-16430534(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:Gp5IWqWrBXlXLtZ/K/fkkGHncHc9606	rigid:NzbxgrxZr704cltpDah83mavur8	true	-	sufficient binding region:465-729	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P30279	uniprotkb:Q00535-2	intact:EBI-748789|uniprotkb:Q13955|uniprotkb:Q5U035|uniprotkb:A8K531|ensembl:ENSP00000261254|ensembl:ENSP00000502597|ensembl:ENSP00000502654	intact:EBI-16466150|ensembl:ENSP00000297518	psi-mi:ccnd2_human(display_long)|uniprotkb:CCND2(gene name)|psi-mi:CCND2(display_short)	psi-mi:q00535-2(display_long)|uniprotkb:Cell division protein kinase 5(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PSSALRE(gene name synonym)|uniprotkb:Tau protein kinase II catalytic subunit(gene name synonym)|uniprotkb:CDK5-SV(isoform synonym)|uniprotkb:CDK5(gene name)|psi-mi:CDK5(display_short)|uniprotkb:CDKN5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466158	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001750.1|ensembl:ENSG00000118971(gene)|ensembl:ENST00000261254(transcript)|ensembl:ENST00000676279(transcript)|ensembl:ENST00000676411(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015451(Cyclin D)|interpro:IPR036915|interpro:IPR039361|mint:P30279|rcsb pdb:6EI2|reactome:R-HSA-69231|reactome:R-HSA-8934593|reactome:R-HSA-9661069|go:"GO:0005829"(cytosol)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|dip:DIP-178N|entrezgene/locuslink:894(identity)	ensembl:ENSG00000164885(gene)|ensembl:ENST00000297518(transcript)|intact:EBI-1041567(isoform-parent)|entrezgene/locuslink:1020(identity)	intact:EBI-16437667(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7DtKJiw07/E5uNvUagbYbcAo7kM9606	rogid:pxKjln6Un7Mq+4T2JOI8igx0S2E9606	rigid:4Vi5IuVIlpqvnkHKxznyiW+w2MA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15645	uniprotkb:P27918	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	intact:EBI-9038570|uniprotkb:O15134|uniprotkb:O15135|uniprotkb:O15136|uniprotkb:O75826|ensembl:ENSP00000247153|ensembl:ENSP00000380189	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:prop_human(display_long)|uniprotkb:CFP(gene name)|psi-mi:CFP(display_short)|uniprotkb:PFC(gene name synonym)|uniprotkb:Complement factor P(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466174	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P|entrezgene/locuslink:9319(identity)	refseq:NP_001138724.1|refseq:NP_002612.1|ensembl:ENSG00000126759(gene)|ensembl:ENST00000247153(transcript)|ensembl:ENST00000396992(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006955"(immune response)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042742"(defense response to bacterium)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR036383|rcsb pdb:1W0R|rcsb pdb:1W0S|rcsb pdb:6RUR|rcsb pdb:6RUS|rcsb pdb:6RUV|rcsb pdb:6RV6|rcsb pdb:6S08|rcsb pdb:6S0A|rcsb pdb:6S0B|rcsb pdb:6SEJ|reactome:R-HSA-173736|reactome:R-HSA-174577|reactome:R-HSA-5083635|reactome:R-HSA-5173214|reactome:R-HSA-6798695|reactome:R-HSA-977606|entrezgene/locuslink:5199(identity)	intact:EBI-16434712(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	rogid:XBExMxbnkfjvnV9zHMRZgxZWKaw9606	rigid:nwEQIo78bTwdV/Ok1tvCtDrSwDY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0-2	uniprotkb:A0A0S2Z3J3	intact:EBI-10173939|ensembl:ENSP00000257468	intact:EBI-16466190	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:a0a0s2z3j3_human(display_long)|uniprotkb:CLCN2(gene name)|psi-mi:CLCN2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466199	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR014743(Chloride channel, core)|interpro:IPR001807(Chloride channel, voltage gated)|entrezgene/locuslink:1181(identity)	intact:EBI-16431121(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rogid:jAqpY5lOQfTB1nAYqNwXBCHTVCk9606	rigid:zMOFtUSqyjld1BSIGh+lhsHWygU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0-2	uniprotkb:A0A0S2Z3G7	intact:EBI-10173939|ensembl:ENSP00000257468	intact:EBI-16466215	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:a0a0s2z3g7_human(display_long)|uniprotkb:CLCN2(gene name)|psi-mi:CLCN2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466224	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR014743(Chloride channel, core)|interpro:IPR001807(Chloride channel, voltage gated)|entrezgene/locuslink:1181(identity)	intact:EBI-16431121(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rogid:JvPbgQ8n9O7hA1kBCmeExmxyX149606	rigid:r5RWj0HuoNITJjrckpCBMzeQ14s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0-2	uniprotkb:A0A0S2Z368	intact:EBI-10173939|ensembl:ENSP00000257468	intact:EBI-16466240	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:a0a0s2z368_human(display_long)|uniprotkb:CLCN2(gene name)|psi-mi:CLCN2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466243	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR014743(Chloride channel, core)|entrezgene/locuslink:1181(identity)	intact:EBI-16431121(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rogid:QqkkEDwGhMlbxJz7AWZzkw7EAeo9606	rigid:SuX5f8lWsI8EFWII9A9VBF+mHv4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13643	uniprotkb:A0A0S2Z3J3	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	intact:EBI-16466190	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:a0a0s2z3j3_human(display_long)|uniprotkb:CLCN2(gene name)|psi-mi:CLCN2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466259	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR014743(Chloride channel, core)|interpro:IPR001807(Chloride channel, voltage gated)|entrezgene/locuslink:1181(identity)	intact:EBI-16435554(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	rogid:jAqpY5lOQfTB1nAYqNwXBCHTVCk9606	rigid:aNozi6GlDkVv3kZ8Bvj+78oweoQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13643	uniprotkb:A0A0S2Z3G7	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	intact:EBI-16466215	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:a0a0s2z3g7_human(display_long)|uniprotkb:CLCN2(gene name)|psi-mi:CLCN2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466275	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR014743(Chloride channel, core)|interpro:IPR001807(Chloride channel, voltage gated)|entrezgene/locuslink:1181(identity)	intact:EBI-16435554(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	rogid:JvPbgQ8n9O7hA1kBCmeExmxyX149606	rigid:sJP/1W3h+/JRFhkCLG4pZgpixxY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13643	uniprotkb:A0A0S2Z368	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	intact:EBI-16466240	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:a0a0s2z368_human(display_long)|uniprotkb:CLCN2(gene name)|psi-mi:CLCN2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466291	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR014743(Chloride channel, core)|entrezgene/locuslink:1181(identity)	intact:EBI-16435554(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	rogid:QqkkEDwGhMlbxJz7AWZzkw7EAeo9606	rigid:eb0f9JZuRlj3xh0JdqES8YczcH0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q86VP1	uniprotkb:A0A0S2Z604	intact:EBI-529518|uniprotkb:O60398|uniprotkb:O95770|uniprotkb:Q13311|uniprotkb:Q9BQG5|uniprotkb:Q9UI88|uniprotkb:B4DKU7|uniprotkb:E7ENV2|uniprotkb:A4D196|ensembl:ENSP00000379612	intact:EBI-16430119	psi-mi:taxb1_human(display_long)|uniprotkb:TRAF6-binding protein(gene name synonym)|uniprotkb:TAX1BP1(gene name)|psi-mi:TAX1BP1(display_short)|uniprotkb:T6BP(gene name synonym)|uniprotkb:PRO0105(orf name)	psi-mi:a0a0s2z604_human(display_long)|uniprotkb:COG7(gene name)|psi-mi:COG7(display_short)|uniprotkb:Conserved oligomeric Golgi complex subunit 7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466307	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001073333.1|refseq:NP_001193830.1|refseq:NP_001193831.1|refseq:NP_006015.4|dip:DIP-33010N|ensembl:ENSG00000106052(gene)|ensembl:ENST00000396319(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0019900"(kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q86VP1|rcsb pdb:2M7Q|rcsb pdb:4BMJ|rcsb pdb:4NLH|rcsb pdb:4Z4K|rcsb pdb:4Z4M|rcsb pdb:5AAS|rcsb pdb:5YT6|rcsb pdb:5Z7G|reactome:R-HSA-5357905|reactome:R-HSA-936440|entrezgene/locuslink:8887(identity)	go:"GO:0000139"(Golgi membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0017119"(Golgi transport complex)|interpro:IPR019335|entrezgene/locuslink:91949(identity)	intact:EBI-16430385(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OJfD9nSzpjJ3bMbHugSDVJ9fj/E9606	rogid:tyBD/wDJzjaIBQVhEFlQTm1Ptec9606	rigid:rHtfEUJEohyewBXuvAuQZJgKwT8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UP83-3	uniprotkb:P83436	intact:EBI-16431689	intact:EBI-389534|uniprotkb:Q6UWU7|ensembl:ENSP00000305442	psi-mi:q9up83-3(display_long)|uniprotkb:13S Golgi transport complex 90 kDa subunit(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 5(gene name synonym)|uniprotkb:Golgi transport complex 1(gene name synonym)|uniprotkb:COG5(gene name)|psi-mi:COG5(display_short)|uniprotkb:GOLTC1(gene name synonym)|uniprotkb:GTC90(gene name synonym)	psi-mi:cog7_human(display_long)|uniprotkb:UNQ3082/PRO10013(orf name)|uniprotkb:COG7(gene name)|psi-mi:COG7(display_short)|uniprotkb:Component of oligomeric Golgi complex 7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466323	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-389502(isoform-parent)|entrezgene/locuslink:10466(identity)	refseq:NP_705831.1|ensembl:ENSG00000168434(gene)|ensembl:ENST00000307149(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050821"(protein stabilization)|interpro:IPR019335|mint:P83436|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|entrezgene/locuslink:91949(identity)	intact:EBI-16431696(see-also)	isoform-comment:No experimental confirmation available.	-	comment:"Evidence for isoform CCSB isoform ID: COG7_1 expression is provided in figureS2C."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8d6Z5Ozyy5EOhcfo2J/n6PKdF409606	rogid:H0hZTc8M4oCkuEUCOMEMJ122BeY9606	rigid:ZefIs3myeOmkHS4UlcNP1U6MkUI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y6C2-2	uniprotkb:P83436	intact:EBI-11748557	intact:EBI-389534|uniprotkb:Q6UWU7|ensembl:ENSP00000305442	psi-mi:q9y6c2-2(display_long)|uniprotkb:EMILIN1(gene name)|psi-mi:EMILIN1(display_short)|uniprotkb:EMI(gene name synonym)|uniprotkb:Elastin microfibril interface-located protein 1(gene name synonym)	psi-mi:cog7_human(display_long)|uniprotkb:UNQ3082/PRO10013(orf name)|uniprotkb:COG7(gene name)|psi-mi:COG7(display_short)|uniprotkb:Component of oligomeric Golgi complex 7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466339	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-744586(isoform-parent)|uniprotkb:Q9Y6C2-2(isoform-parent)|entrezgene/locuslink:11117(identity)	refseq:NP_705831.1|ensembl:ENSG00000168434(gene)|ensembl:ENST00000307149(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050821"(protein stabilization)|interpro:IPR019335|mint:P83436|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|entrezgene/locuslink:91949(identity)	intact:EBI-16440082(see-also)	isoform-comment:No experimental confirmation available.	-	comment:"Evidence for isoform CCSB isoform ID: COG7_1 expression is provided in figureS2C."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:NGDxonJvrK0A9caBPSPej/CS+q89606	rogid:H0hZTc8M4oCkuEUCOMEMJ122BeY9606	rigid:2FiFGR7SstOSLM4pmLXFQXubNco	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6PIL6	uniprotkb:A0A0S2Z3K0	intact:EBI-1051469|uniprotkb:Q4W5G8|uniprotkb:Q8NEU0|uniprotkb:Q9BWT2|uniprotkb:Q9H294|uniprotkb:Q9H2A4|uniprotkb:Q3YAB9|uniprotkb:Q3YAC0|uniprotkb:Q3YAB8|uniprotkb:Q3YAC1|uniprotkb:Q3YAC2|ensembl:ENSP00000371587	intact:EBI-16431143	psi-mi:kcip4_human(display_long)|uniprotkb:A-type potassium channel modulatory protein 4(gene name synonym)|uniprotkb:Potassium channel-interacting protein 4(gene name synonym)|uniprotkb:Calsenilin-like protein(gene name synonym)|uniprotkb:KCNIP4(gene name)|psi-mi:KCNIP4(display_short)|uniprotkb:CALP(gene name synonym)|uniprotkb:KCHIP4(gene name synonym)	psi-mi:a0a0s2z3k0_human(display_long)|uniprotkb:COL1A2(gene name)|psi-mi:COL1A2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466355	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001030176.1|refseq:NP_079497.2|refseq:NP_671710.1|refseq:NP_671711.1|refseq:NP_671712.1|refseq:NP_001030175.1|refseq:XP_016864142.1|ensembl:ENSG00000185774(gene)|ensembl:ENST00000382152(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|reactome:R-HSA-5576894|entrezgene/locuslink:80333(identity)	go:"GO:0005581"(collagen trimer)|interpro:IPR008160(Collagen triple helix repeat)|entrezgene/locuslink:1278(identity)	intact:EBI-16429045(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ihBpvroA94ZQzV1E9Y79lF8xmqc9606	rogid:UpD+NxJv+KzbpC6BW3iMpACMxCk9606	rigid:buponVSb5wkL6KU7M6q8lrgSyrg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:Q9BT78	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-742413|uniprotkb:Q561W7|uniprotkb:Q9NW31|uniprotkb:Q9Y677|uniprotkb:B3KN88|ensembl:ENSP00000264389|uniprotkb:B3KST5	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:csn4_human(display_long)|uniprotkb:COPS4(gene name)|psi-mi:COPS4(display_short)|uniprotkb:CSN4(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466371	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	ensembl:ENSG00000138663(gene)|refseq:NP_057213.2|refseq:NP_001244935.1|go:"GO:0016607"(nuclear speck)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0030054"(cell junction)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406|mint:Q9BT78|rcsb pdb:4D0P|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|ensembl:ENST00000264389(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|refseq:NP_001317656.1|dip:DIP-34516N|entrezgene/locuslink:51138(identity)	intact:EBI-16432802(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: COPS4_1 expression is provided in figureS2E."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:onrZiPzG+bZvycmpDTZMtkPzCfQ9606	rigid:gp4ZN8AgYJUbI9P1dU8sCsbJIyk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P08727	intact:EBI-16432800	intact:EBI-742756|uniprotkb:Q5XG83|uniprotkb:Q6NW33|uniprotkb:Q7L5M9|uniprotkb:Q96A53|uniprotkb:Q96FV1|uniprotkb:Q9BYF9|uniprotkb:Q9P1Y4|uniprotkb:B2R874|ensembl:ENSP00000355124	-	psi-mi:k1c19_human(display_long)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:KRT19(gene name)|psi-mi:KRT19(display_short)	psi-mi:"ccsb isoform id: cops4_2"(display_short)|psi-mi:EBI-16432800(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466387	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002267.2|ensembl:ENSG00000171345(gene)|ensembl:ENST00000361566(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08727|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-35655N|entrezgene/locuslink:3880(identity)	entrezgene/locuslink:51138(identity)	intact:EBI-16435370(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: COPS4_2 expression is provided in figureS2E."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fqsG2nghpcmTtI39LiYVLNYuFIA9606	rogid:vPY3rKRE6kWXbUK0bKK5SHSR+409606	rigid:jtm1QzO9sbkRG7UJfsr+SFXT/V4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N6Y0	intact:EBI-16432800	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	-	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"ccsb isoform id: cops4_2"(display_short)|psi-mi:EBI-16432800(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466403	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	entrezgene/locuslink:51138(identity)	intact:EBI-16439799(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: COPS4_2 expression is provided in figureS2E."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:vPY3rKRE6kWXbUK0bKK5SHSR+409606	rigid:3fBg86Cj6SDpnsGSMo74R8yL5W8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND30	uniprotkb:P46108	intact:EBI-744056|uniprotkb:O75337|uniprotkb:Q8WW26|intact:EBI-28975311|uniprotkb:B7Z433|uniprotkb:E9PK77|ensembl:ENSP00000299492	intact:EBI-886|uniprotkb:B0LPE8|uniprotkb:Q96HJ0|uniprotkb:A8MWE8|uniprotkb:Q96GA9|uniprotkb:D3DTH6|intact:EBI-28974221|ensembl:ENSP00000300574|intact:EBI-16429791	psi-mi:lipb2_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2(gene name synonym)|uniprotkb:PPFIBP2(gene name)|psi-mi:PPFIBP2(display_short)	psi-mi:crk_human(display_long)|uniprotkb:Proto-oncogene c-Crk(gene name synonym)|uniprotkb:CRK(gene name)|psi-mi:CRK(display_short)|uniprotkb:p38(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466419	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003612.2|ensembl:ENSP00000299492|ensembl:ENST00000528883|ensembl:ENSP00000435469|ensembl:ENST00000530181|ensembl:ENSP00000437321|refseq:NP_001243497.1|refseq:XP_016873932.1|dip:DIP-42373N|ensembl:ENSG00000166387(gene)|ensembl:ENST00000299492(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030435|interpro:IPR037617|interpro:IPR037618|interpro:IPR037619|mint:Q8ND30|rcsb pdb:3QH9|reactome:R-HSA-388844|entrezgene/locuslink:8495(identity)	ensembl:ENSP00000300574|ensembl:ENST00000398970|ensembl:ENSP00000381942|refseq:NP_005197.3|refseq:NP_058431.2|ensembl:ENSG00000167193(gene)|ensembl:ENST00000300574(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001878"(response to yeast)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|dip:DIP-199N|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019900"(kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035728"(response to hepatocyte growth factor)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045121"(membrane raft)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902531"(regulation of intracellular signal transduction)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46108|rcsb pdb:1JU5|rcsb pdb:2DVJ|rcsb pdb:2EYV|rcsb pdb:2EYW|rcsb pdb:2EYX|rcsb pdb:2EYY|rcsb pdb:2EYZ|rcsb pdb:2MS4|rcsb pdb:5UL6|rcsb pdb:6ATV|reactome:R-HSA-170984|reactome:R-HSA-186763|reactome:R-HSA-2029482|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-912631|reactome:R-HSA-9664422|entrezgene/locuslink:1398(identity)	intact:EBI-16431778(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:36bMLWHJuGN5eItyc1HvhoLonZA9606	rogid:lIXCzFxFvmvsfPaLQIKV9QS75cw9606	rigid:TVu3IYjzNPduuCgZ4M09VNAei9M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P41970	uniprotkb:P46108	intact:EBI-1758534|uniprotkb:Q6FG57|uniprotkb:Q6GU29|uniprotkb:Q9UD17|uniprotkb:B2R6S6|ensembl:ENSP00000228741	intact:EBI-886|uniprotkb:B0LPE8|uniprotkb:Q96HJ0|uniprotkb:A8MWE8|uniprotkb:Q96GA9|uniprotkb:D3DTH6|intact:EBI-28974221|ensembl:ENSP00000300574|intact:EBI-16429791	psi-mi:elk3_human(display_long)|uniprotkb:ELK3(gene name)|psi-mi:ELK3(display_short)|uniprotkb:NET(gene name synonym)|uniprotkb:SAP2(gene name synonym)|uniprotkb:ETS-related protein NET(gene name synonym)|uniprotkb:ETS-related protein ERP(gene name synonym)|uniprotkb:Serum response factor accessory protein 2(gene name synonym)	psi-mi:crk_human(display_long)|uniprotkb:Proto-oncogene c-Crk(gene name synonym)|uniprotkb:CRK(gene name)|psi-mi:CRK(display_short)|uniprotkb:p38(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466435	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005221.2|refseq:XP_006719338.1|ensembl:ENSG00000111145(gene)|ensembl:ENST00000228741(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0042060"(wound healing)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|entrezgene/locuslink:2004(identity)	ensembl:ENSP00000300574|ensembl:ENST00000398970|ensembl:ENSP00000381942|refseq:NP_005197.3|refseq:NP_058431.2|ensembl:ENSG00000167193(gene)|ensembl:ENST00000300574(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001878"(response to yeast)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|dip:DIP-199N|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019900"(kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035728"(response to hepatocyte growth factor)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045121"(membrane raft)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902531"(regulation of intracellular signal transduction)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46108|rcsb pdb:1JU5|rcsb pdb:2DVJ|rcsb pdb:2EYV|rcsb pdb:2EYW|rcsb pdb:2EYX|rcsb pdb:2EYY|rcsb pdb:2EYZ|rcsb pdb:2MS4|rcsb pdb:5UL6|rcsb pdb:6ATV|reactome:R-HSA-170984|reactome:R-HSA-186763|reactome:R-HSA-2029482|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-912631|reactome:R-HSA-9664422|entrezgene/locuslink:1398(identity)	intact:EBI-16437677(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:iPkf41e5YQWRa3P5QiEz/npvNgM9606	rogid:lIXCzFxFvmvsfPaLQIKV9QS75cw9606	rigid:5RSOtc25JPI6hFuIsiWZKbOMW5M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N205-2	intact:EBI-16466451	intact:EBI-12099160|ensembl:ENSP00000343152	-	psi-mi:q8n205-2(display_long)|uniprotkb:SYNE4(gene name)|psi-mi:SYNE4(display_short)|uniprotkb:C19orf46(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 4(gene name synonym)|uniprotkb:KASH domain-containing protein 4(gene name synonym)	psi-mi:"ccsb isoform id: csgalnact2_3"(display_short)|psi-mi:EBI-16466451(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466454	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181392(gene)|ensembl:ENST00000340477(transcript)|intact:EBI-7131783(isoform-parent)|uniprotkb:Q8N205-2(isoform-parent)|entrezgene/locuslink:163183(identity)	entrezgene/locuslink:55454(identity)	intact:EBI-16434758(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:wZZnrCoICL0cSTPDAK5tBR6uoAk9606	rogid:mpixmCTfLzsS2yiPVxjCibJKsm49606	rigid:nO/VzYfiAqvnynKwjVEV4mqF5H8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:P49682	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-12836456|ensembl:ENSP00000362797|uniprotkb:B2R982|uniprotkb:O15185|uniprotkb:Q7Z710|uniprotkb:Q9P2T4|uniprotkb:Q9P2T5	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:cxcr3_human(display_long)|uniprotkb:CXCR3(gene name)|psi-mi:CXCR3(display_short)|uniprotkb:CKR-L2(gene name synonym)|uniprotkb:G protein-coupled receptor 9(gene name synonym)|uniprotkb:GPR9(gene name synonym)|uniprotkb:Interferon-inducible protein 10 receptor(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466470	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	go:"GO:0038023"(signaling receptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR004070(C-X-C chemokine receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0030155"(regulation of cell adhesion)|ensembl:ENSG00000186810(gene)|ensembl:ENST00000373693(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019956"(chemokine binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|refseq:NP_001136269.1|refseq:NP_001495.1|refseq:XP_016884924.1|dip:DIP-5891N|entrezgene/locuslink:2833(identity)	intact:EBI-16432546(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:P9WxnLkV6IH50a6feWDd6KsoNlA9606	rigid:I7HJgWKXtRx54VBh8CdtdsrF+3U	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NP66	uniprotkb:Q9UJW0	intact:EBI-740641|ensembl:ENSP00000336856|ensembl:ENSP00000371133|uniprotkb:A6NHY3|uniprotkb:Q53G31|uniprotkb:Q9NSF6|uniprotkb:D3DW78	intact:EBI-2134033|uniprotkb:Q8TAN8|uniprotkb:D3DQH0|intact:EBI-2559420|uniprotkb:B3KWW0|uniprotkb:E5RGT5|ensembl:ENSP00000416968	psi-mi:hm20a_human(display_long)|uniprotkb:HMG box-containing protein 20A(gene name synonym)|uniprotkb:HMG domain-containing protein HMGX1(gene name synonym)|uniprotkb:HMG20A(gene name)|psi-mi:HMG20A(display_short)|uniprotkb:HMGX1(gene name synonym)|uniprotkb:HMGXB1(gene name synonym)|uniprotkb:HMG domain-containing protein 1(gene name synonym)	psi-mi:dctn4_human(display_long)|uniprotkb:DCTN4(gene name)|psi-mi:DCTN4(display_short)|uniprotkb:Dynactin subunit p62(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466486	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060670.1|ensembl:ENSG00000140382(gene)|ensembl:ENST00000336216(transcript)|ensembl:ENST00000381714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q9NP66|refseq:NP_001291433.1|refseq:NP_001291434.1|refseq:XP_011519460.1|entrezgene/locuslink:10363(identity)	refseq:XP_011535946.1|refseq:XP_011535947.1|refseq:NP_001129116.1|refseq:NP_057305.1|refseq:NP_001129115.1|ensembl:ENSG00000132912(gene)|ensembl:ENST00000447998(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005869"(dynactin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0030017"(sarcomere)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008603(Dynactin p62)|mint:Q9UJW0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|entrezgene/locuslink:51164(identity)	intact:EBI-16432592(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:LhilayeP+xv97pbYzIA8yMvwUbc9606	rogid:JradQZl06O4u9N3HH+cpvdP05RA9606	rigid:7x1gb+ZU+yl4EAh4l2qfaD0WCGY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NP66	uniprotkb:A0A0S2Z5B8	intact:EBI-740641|ensembl:ENSP00000336856|ensembl:ENSP00000371133|uniprotkb:A6NHY3|uniprotkb:Q53G31|uniprotkb:Q9NSF6|uniprotkb:D3DW78	intact:EBI-16466502	psi-mi:hm20a_human(display_long)|uniprotkb:HMG box-containing protein 20A(gene name synonym)|uniprotkb:HMG domain-containing protein HMGX1(gene name synonym)|uniprotkb:HMG20A(gene name)|psi-mi:HMG20A(display_short)|uniprotkb:HMGX1(gene name synonym)|uniprotkb:HMGXB1(gene name synonym)|uniprotkb:HMG domain-containing protein 1(gene name synonym)	psi-mi:a0a0s2z5b8_human(display_long)|uniprotkb:DCTN4(gene name)|psi-mi:DCTN4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466509	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060670.1|ensembl:ENSG00000140382(gene)|ensembl:ENST00000336216(transcript)|ensembl:ENST00000381714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q9NP66|refseq:NP_001291433.1|refseq:NP_001291434.1|refseq:XP_011519460.1|entrezgene/locuslink:10363(identity)	go:"GO:0005869"(dynactin complex)|interpro:IPR008603(Dynactin p62)|entrezgene/locuslink:51164(identity)	intact:EBI-16432592(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:LhilayeP+xv97pbYzIA8yMvwUbc9606	rogid:YbENGRFyl7aDyzeVH/us/i2mScQ9606	rigid:FuE4sN6NCBNquN9rycqCGPkrRxc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z5D5	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16432590	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z5d5_human(display_long)|uniprotkb:DCTN4(gene name)|psi-mi:DCTN4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466544	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	entrezgene/locuslink:51164(identity)	intact:EBI-16438444(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:c2CExeSJVtEGU1+sUEgWSSI9ZVc9606	rigid:8u1xxfKbuhbcco/xawYSDjLxrLY	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z5B8	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16466502	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z5b8_human(display_long)|uniprotkb:DCTN4(gene name)|psi-mi:DCTN4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466525	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0005869"(dynactin complex)|interpro:IPR008603(Dynactin p62)|entrezgene/locuslink:51164(identity)	intact:EBI-16438444(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:YbENGRFyl7aDyzeVH/us/i2mScQ9606	rigid:lw5Jf/tco3aHGm5BOEvdaasSHvQ	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00471	uniprotkb:Q8WXU2-2	intact:EBI-949824|ensembl:ENSP00000484855|uniprotkb:B2R6C5|intact:EBI-10171392|uniprotkb:Q8IW24	intact:EBI-9381887|ensembl:ENSP00000403412	psi-mi:exoc5_human(display_long)|uniprotkb:Exocyst complex component Sec10(gene name synonym)|uniprotkb:EXOC5(gene name)|psi-mi:EXOC5(display_short)|uniprotkb:SEC10(gene name synonym)|uniprotkb:SEC10L1(gene name synonym)	psi-mi:q8wxu2-2(display_long)|uniprotkb:DNAAF4(gene name)|psi-mi:DNAAF4(display_short)|uniprotkb:DYX1C1(gene name synonym)|uniprotkb:Dyslexia susceptibility 1 candidate gene 1 protein(gene name synonym)|uniprotkb:EKN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466713	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070367(gene)|ensembl:ENST00000621441(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904019"(epithelial cell apoptotic process)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009976(Exocyst complex component Sec10)|interpro:IPR033960|mint:O00471|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:NP_006535.1|entrezgene/locuslink:10640(identity)	ensembl:ENSG00000256061(gene)|ensembl:ENST00000448430(transcript)|uniprotkb:Q8WXU2-2(isoform-parent)|intact:EBI-2946907(isoform-parent)|entrezgene/locuslink:161582(identity)	intact:EBI-16430219(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UaEk0DAH+boE9+hl8z3VUUI78dM9606	rogid:jYtZBqy6D77KSvFPNp8nBddDD1s9606	rigid:/L3X/1o/laqq0ILl5IqndU7Dpx0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UPQ8	uniprotkb:Q9UMX0-2	intact:EBI-8645574|ensembl:ENSP00000361667|uniprotkb:Q5SRE6|intact:MINT-4724096|intact:MINT-8163513	intact:EBI-10173939|ensembl:ENSP00000257468	psi-mi:dolk_human(display_long)|uniprotkb:KIAA1094(gene name synonym)|uniprotkb:UNQ2422/PRO4980(orf name)|uniprotkb:DOLK(gene name)|psi-mi:DOLK(display_short)|uniprotkb:TMEM15(gene name synonym)|uniprotkb:Transmembrane protein 15(gene name synonym)	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466662	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000175283(gene)|ensembl:ENST00000372586(transcript)|go:"GO:0004168"(dolichol kinase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006489"(dolichyl diphosphate biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043048"(dolichyl monophosphate biosynthetic process)|interpro:IPR026566|interpro:IPR032974|reactome:R-HSA-446199|reactome:R-HSA-4755583|refseq:NP_055723.1|entrezgene/locuslink:22845(identity)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	intact:EBI-16431167(see-also)	function:"Defects in TMEM15 are the cause of congenital disorder of glycosylation type 1M (CDG1M) [MIM:610768]; also known as dolichol kinase deficiency. CDGs are a family of severe inherited diseases caused by a defect in glycoprotein biosynthesis. They are characterized by under-glycosylated serum glycoproteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. CDG1M is a very severe disorder with death occurring in early infancy"	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:oVMRd2DWTKCgO7cySF3k2IbBfn09606	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rigid:Q4a0WtyOeUoewKJV4Poln8Y6ELo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P22001	uniprotkb:A0A0S2Z5Y1	intact:EBI-8627664|ensembl:ENSP00000358784|intact:MINT-1528422|uniprotkb:Q5VWN2	intact:EBI-16431159	psi-mi:kcna3_human(display_long)|uniprotkb:KCNA3(gene name)|psi-mi:KCNA3(display_short)|uniprotkb:HGK5(gene name synonym)|uniprotkb:HPCN3(gene name synonym)|uniprotkb:HLK3(gene name synonym)|uniprotkb:"Voltage-gated K(+) channel HuKIII"(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv1.3(gene name synonym)	psi-mi:a0a0s2z5y1_human(display_long)|uniprotkb:DOLK(gene name)|psi-mi:DOLK(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466694	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR004050(Potassium channel, voltage dependent, Kv1.3)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:4BGC|rcsb pdb:7EJ1|rcsb pdb:7EJ2|reactome:R-HSA-1296072|go:"GO:0099056"(integral component of presynaptic membrane)|ensembl:ENST00000369769(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|ensembl:ENSG00000177272(gene)|refseq:NP_002223.3|dip:DIP-44822N|entrezgene/locuslink:3738(identity)	go:"GO:0016301"(kinase activity)|interpro:IPR032974|entrezgene/locuslink:22845(identity)	intact:EBI-16432872(see-also)	comment:mint|function:Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:QH0tUFo3Db+XWLTawQfDhma+3jg9606	rogid:/tQYfLrD7OKrWUFrog22eoJZWhA9606	rigid:bEFS9bMvKsyzh27AZCo0Odr8o70	true	sufficient binding region:53-575	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IZU0	uniprotkb:Q16854	intact:EBI-10175124|uniprotkb:Q8N7Z8|uniprotkb:Q0IJ68|ensembl:ENSP00000318716|ensembl:ENSP00000412606|ensembl:ENSP00000431456|ensembl:ENSP00000498495	intact:EBI-3908194|uniprotkb:P78532|uniprotkb:Q16759|uniprotkb:Q4ZG09|uniprotkb:Q96BC1|uniprotkb:Q7L1W9|intact:EBI-16466603|ensembl:ENSP00000264093	psi-mi:fam9b_human(display_long)|uniprotkb:FAM9B(gene name)|psi-mi:FAM9B(display_short)	psi-mi:dguok_human(display_long)|uniprotkb:DGUOK(gene name)|psi-mi:DGUOK(display_short)|uniprotkb:DGK(gene name synonym)|uniprotkb:Deoxyadenosine kinase, mitochondrial(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466606	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_995321.1|refseq:XP_011543766.1|ensembl:ENSG00000177138(gene)|ensembl:ENST00000327220(transcript)|ensembl:ENST00000428477(transcript)|ensembl:ENST00000472522(transcript)|ensembl:ENST00000651278(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|entrezgene/locuslink:171483(identity)	refseq:NP_550438.1|refseq:NP_550440.1|refseq:NP_001305788.1|refseq:NP_001305789.1|refseq:NP_001305790.1|refseq:NP_001305791.1|refseq:NP_001305792.1|ensembl:ENSG00000114956(gene)|ensembl:ENST00000264093(transcript)|go:"GO:0004136"(deoxyadenosine kinase activity)|go:"GO:0004138"(deoxyguanosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008617"(guanosine metabolic process)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0019136"(deoxynucleoside kinase activity)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046070"(dGTP metabolic process)|go:"GO:0046122"(purine deoxyribonucleoside metabolic process)|interpro:IPR002624(Deoxynucleoside kinase)|interpro:IPR027417|interpro:IPR031314|rcsb pdb:2OCP|reactome:R-HSA-74217|entrezgene/locuslink:1716(identity)	intact:EBI-16436769(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:tEJbrpO7KWcw7izp1VJ+5q6Xces9606	rogid:WTctzYSxFE3aQ1L7s9fNMkw8nII9606	rigid:k3zOQaqmy0R6gUTqoer73JMX4mY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:Q9NR28-3	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-16466622|ensembl:ENSP00000320343	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:q9nr28-3(display_long)|uniprotkb:Direct IAP-binding protein with low pI(gene name synonym)|uniprotkb:Second mitochondria-derived activator of caspase(gene name synonym)|uniprotkb:SMAC3(isoform synonym)|uniprotkb:DIABLO(gene name)|psi-mi:DIABLO(display_short)|uniprotkb:SMAC(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466646	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	intact:EBI-517508(isoform-parent)|ensembl:ENST00000353548(transcript)|ensembl:ENSG00000184047(gene)|entrezgene/locuslink:56616(identity)	intact:EBI-16439070(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:MofZ1Z5vpCxl/pplvbGJlHn9oqQ9606	rigid:QdU3tL6Iyt/N7bEgCfKgh7Jardk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15041	uniprotkb:Q9NR28-3	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	intact:EBI-16466622|ensembl:ENSP00000320343	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:q9nr28-3(display_long)|uniprotkb:Direct IAP-binding protein with low pI(gene name synonym)|uniprotkb:Second mitochondria-derived activator of caspase(gene name synonym)|uniprotkb:SMAC3(isoform synonym)|uniprotkb:DIABLO(gene name)|psi-mi:DIABLO(display_short)|uniprotkb:SMAC(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466630	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	intact:EBI-517508(isoform-parent)|ensembl:ENST00000353548(transcript)|ensembl:ENSG00000184047(gene)|entrezgene/locuslink:56616(identity)	intact:EBI-16432884(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rogid:MofZ1Z5vpCxl/pplvbGJlHn9oqQ9606	rigid:dANcD71avPgXLRaiAk7eR7+oomQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IZU0	uniprotkb:Q16854	intact:EBI-10175124|uniprotkb:Q8N7Z8|uniprotkb:Q0IJ68|ensembl:ENSP00000318716|ensembl:ENSP00000412606|ensembl:ENSP00000431456|ensembl:ENSP00000498495	intact:EBI-3908194|uniprotkb:P78532|uniprotkb:Q16759|uniprotkb:Q4ZG09|uniprotkb:Q96BC1|uniprotkb:Q7L1W9|intact:EBI-16466603|ensembl:ENSP00000264093	psi-mi:fam9b_human(display_long)|uniprotkb:FAM9B(gene name)|psi-mi:FAM9B(display_short)	psi-mi:dguok_human(display_long)|uniprotkb:DGUOK(gene name)|psi-mi:DGUOK(display_short)|uniprotkb:DGK(gene name synonym)|uniprotkb:Deoxyadenosine kinase, mitochondrial(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466587	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_995321.1|refseq:XP_011543766.1|ensembl:ENSG00000177138(gene)|ensembl:ENST00000327220(transcript)|ensembl:ENST00000428477(transcript)|ensembl:ENST00000472522(transcript)|ensembl:ENST00000651278(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|entrezgene/locuslink:171483(identity)	refseq:NP_550438.1|refseq:NP_550440.1|refseq:NP_001305788.1|refseq:NP_001305789.1|refseq:NP_001305790.1|refseq:NP_001305791.1|refseq:NP_001305792.1|ensembl:ENSG00000114956(gene)|ensembl:ENST00000264093(transcript)|go:"GO:0004136"(deoxyadenosine kinase activity)|go:"GO:0004138"(deoxyguanosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008617"(guanosine metabolic process)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0019136"(deoxynucleoside kinase activity)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046070"(dGTP metabolic process)|go:"GO:0046122"(purine deoxyribonucleoside metabolic process)|interpro:IPR002624(Deoxynucleoside kinase)|interpro:IPR027417|interpro:IPR031314|rcsb pdb:2OCP|reactome:R-HSA-74217|entrezgene/locuslink:1716(identity)	intact:EBI-16436769(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:tEJbrpO7KWcw7izp1VJ+5q6Xces9606	rogid:WTctzYSxFE3aQ1L7s9fNMkw8nII9606	rigid:k3zOQaqmy0R6gUTqoer73JMX4mY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UPQ8	uniprotkb:Q9UMX0	intact:EBI-8645574|ensembl:ENSP00000361667|uniprotkb:Q5SRE6|intact:MINT-4724096|intact:MINT-8163513	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:dolk_human(display_long)|uniprotkb:KIAA1094(gene name synonym)|uniprotkb:UNQ2422/PRO4980(orf name)|uniprotkb:DOLK(gene name)|psi-mi:DOLK(display_short)|uniprotkb:TMEM15(gene name synonym)|uniprotkb:Transmembrane protein 15(gene name synonym)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466678	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000175283(gene)|ensembl:ENST00000372586(transcript)|go:"GO:0004168"(dolichol kinase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006489"(dolichyl diphosphate biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043048"(dolichyl monophosphate biosynthetic process)|interpro:IPR026566|interpro:IPR032974|reactome:R-HSA-446199|reactome:R-HSA-4755583|refseq:NP_055723.1|entrezgene/locuslink:22845(identity)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	intact:EBI-16432812(see-also)	function:"Defects in TMEM15 are the cause of congenital disorder of glycosylation type 1M (CDG1M) [MIM:610768]; also known as dolichol kinase deficiency. CDGs are a family of severe inherited diseases caused by a defect in glycoprotein biosynthesis. They are characterized by under-glycosylated serum glycoproteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. CDG1M is a very severe disorder with death occurring in early infancy"	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:oVMRd2DWTKCgO7cySF3k2IbBfn09606	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rigid:sKr41ALojKLKhYejm2Sgr3FdRKo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NF50	uniprotkb:Q9BSJ6	intact:EBI-2548605|uniprotkb:B7ZLP0|uniprotkb:E9PH09|ensembl:ENSP00000394888|uniprotkb:A2A350|uniprotkb:A2BDF2|uniprotkb:A4FU78|uniprotkb:Q3MV16|uniprotkb:Q5JPJ1|uniprotkb:Q8TEP1|uniprotkb:Q8WUY2|uniprotkb:Q9BYJ5|uniprotkb:Q9H1Q2|uniprotkb:Q9H1Q3|uniprotkb:Q9H308|uniprotkb:Q9H7P2|intact:EBI-11070681	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:dock8_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467251	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516347.1|refseq:XP_011516349.1|ensembl:ENSG00000107099(gene)|ensembl:ENST00000432829(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061485"(memory T cell proliferation)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-983231|refseq:XP_011516350.1|refseq:NP_001177387.1|refseq:NP_001180465.1|refseq:NP_982272.2|refseq:XP_016870662.1|entrezgene/locuslink:81704(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16439048(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:4ENO+3IOKfCUicfg8fxFQbwf4fg9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:i9naM6SDUcWAcsgH2HRhBa8mlTI	true	sufficient binding region:1587-2099	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q969L2	uniprotkb:Q9BSJ6	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467235	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240|entrezgene/locuslink:114569(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16437235(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:pyMAWN8gcMG8BvHX07CAvpnaajg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96ED9-2	uniprotkb:Q9BSJ6	intact:EBI-10961706|ensembl:ENSP00000264827	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467219	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)|entrezgene/locuslink:29911(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16437215(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:wfUpZAUpq7k1LmdHp7BlpVVb3Nc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	uniprotkb:Q9BSJ6	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467203	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16436002(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:9PAr5YI/fFfX/lsYbrfx9Ac3lSI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7L4P6	uniprotkb:Q9BSJ6	intact:EBI-724373|ensembl:ENSP00000360899|uniprotkb:D3DQ27|uniprotkb:Q96A62|uniprotkb:Q9HAI3|intact:EBI-3044085	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:bend5_human(display_long)|uniprotkb:BEND5(gene name)|psi-mi:BEND5(display_short)|uniprotkb:C1orf165(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467187	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078879.2|ensembl:ENSG00000162373(gene)|ensembl:ENST00000371833(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR018379|interpro:IPR040391|mint:Q7L4P6|refseq:NP_001289011.1|refseq:XP_011540444.1|refseq:XP_016857823.1|entrezgene/locuslink:79656(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16435214(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:R6OwgNU76FX6tqLRdHVmzEgK8EE9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:o1uK/PjbIh/Aj0MNS94tr4m6VF0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96R06	uniprotkb:Q9BSJ6	intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467171	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N|entrezgene/locuslink:10615(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16434150(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:hqeECR9+Yf/hoSnqtfk93gTEkdQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:Q9BSJ6	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467155	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16432218(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:/fegmfVLdC/MrbExQTRzffBtGYs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q9BSJ6	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467139	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16432128(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:sFiTwQCqGFywSi62MN6Su2krW9M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:Q9BSJ6	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16431852(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:H2JbglrA/LBRiTLx1TPAPMZGtak	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6NUQ1	uniprotkb:Q9BSJ6	intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467104	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N|entrezgene/locuslink:60561(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16431615(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:OWLuKZexqiy3AxvQ+gndUjTF23I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N1B4	uniprotkb:Q9BSJ6	intact:EBI-2799833|ensembl:ENSP00000372697|ensembl:ENSP00000390831|ensembl:ENSP00000391197|ensembl:ENSP00000404016|ensembl:ENSP00000406988|ensembl:ENSP00000409952|uniprotkb:B4DNI9|uniprotkb:Q9NPT5|uniprotkb:Q8IUN6|uniprotkb:Q5JPA0|uniprotkb:Q53GR4|uniprotkb:Q5SQW1|uniprotkb:B0UZZ4|uniprotkb:A2BF38	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:vps52_human(display_long)|uniprotkb:SACM2L(gene name synonym)|uniprotkb:SAC2 suppressor of actin mutations 2-like protein(gene name synonym)|uniprotkb:VPS52(gene name)|psi-mi:VPS52(display_short)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467088	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000223501(gene)|ensembl:ENSG00000224455(gene)|ensembl:ENSG00000225590(gene)|ensembl:ENSG00000228425(gene)|ensembl:ENSG00000236014(gene)|ensembl:ENST00000383210(transcript)|ensembl:ENST00000428608(transcript)|ensembl:ENST00000441058(transcript)|ensembl:ENST00000443860(transcript)|ensembl:ENST00000445902(transcript)|ensembl:ENST00000448042(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007041"(lysosomal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048611"(embryonic ectodermal digestive tract development)|go:"GO:0055037"(recycling endosome)|go:"GO:1990745"(EARP complex)|interpro:IPR007258(Vps52/Sac2)|reactome:R-HSA-6811440|ensembl:ENSG00000206286(gene)|refseq:NP_001276104.1|refseq:NP_072047.4|refseq:NP_001276105.1|refseq:XP_016866667.1|dip:DIP-57843N|entrezgene/locuslink:6293(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16430867(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fMptnw5eMhxv+AzDK/+mSKrL7uY9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:VEYrkRwqIMqNyQ4Gvp4/GHDFjns	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q9BSJ6	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467072	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16429917(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:sFiTwQCqGFywSi62MN6Su2krW9M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95273	uniprotkb:Q9BSJ6	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467056	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16428890(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:oVdy0z/sL8nQY4wVN7pC7eagTxk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P43365	intact:EBI-16467021	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	-	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:"ccsb isoform id: fam54b_2"(display_short)|psi-mi:EBI-16467021(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467040	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	entrezgene/locuslink:56181(identity)	intact:EBI-16440312(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:s6tB/T5PNwpafrH/RLNC5RLnCn89606	rigid:Mg/HXliSSKCiVCZFso95L3Evuv0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NVT9	intact:EBI-16467021	intact:EBI-3506974|uniprotkb:Q9H018|uniprotkb:Q9H820|uniprotkb:B4E2W7|ensembl:ENSP00000276569	-	psi-mi:armc1_human(display_long)|uniprotkb:ARMC1(gene name)|psi-mi:ARMC1(display_short)|uniprotkb:ARCP(gene name synonym)	psi-mi:"ccsb isoform id: fam54b_2"(display_short)|psi-mi:EBI-16467021(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467024	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060590.1|ensembl:ENSG00000104442(gene)|ensembl:ENST00000276569(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0046872"(metal ion binding)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|go:"GO:0048312"(intracellular distribution of mitochondria)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016617(Uncharacterised conserved protein UCP013899, metal binding)|interpro:IPR036163|mint:Q9NVT9|refseq:NP_001273631.1|refseq:XP_016869094.1|entrezgene/locuslink:55156(identity)	entrezgene/locuslink:56181(identity)	intact:EBI-16437325(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WP/jzUyBwj/g9TLQ38jY56DYpRI9606	rogid:s6tB/T5PNwpafrH/RLNC5RLnCn89606	rigid:v0q1K18Q39HeDBm3fFkWnuTYI6Y	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:A0A0S2Z6M9	intact:EBI-16439278	intact:EBI-16428876	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:a0a0s2z6m9_human(display_long)|uniprotkb:FAM126A(gene name)|psi-mi:FAM126A(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467005	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR018619|refseq:XP_005249952.1|entrezgene/locuslink:84668(identity)	intact:EBI-16439442(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:BB9OGAPlTXTKfaNW+w3TSxbbHow9606	rigid:jhHPDW+Yjb8M1tzdjfPBmKP9TZI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:Q9BYI3	intact:EBI-16439278	intact:EBI-11065686|uniprotkb:A0A024RA06|uniprotkb:A4D145|uniprotkb:B8ZZJ1|uniprotkb:Q6N010|uniprotkb:Q75MR4|uniprotkb:Q7LDZ4|uniprotkb:Q96MX1|uniprotkb:Q96NQ6|ensembl:ENSP00000403396|intact:EBI-16428864	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:hycci_human(display_long)|uniprotkb:FAM126A(gene name)|psi-mi:FAM126A(display_short)|uniprotkb:DRCTNNB1A(gene name synonym)|uniprotkb:Down-regulated by CTNNB1 protein A(gene name synonym)|uniprotkb:Protein FAM126A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466989	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	refseq:NP_115970.2|refseq:XP_011513891.1|refseq:XP_005249951.1|ensembl:ENSG00000122591(gene)|ensembl:ENST00000432176(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0042552"(myelination)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR018619|rcsb pdb:5DSE|rcsb pdb:6BQ1|entrezgene/locuslink:84668(identity)	intact:EBI-16439442(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:dQX246o/4bB9UkgG+9Be4mIOfxU9606	rigid:0G52UlOtjbg0zUgTgLNO45HrLg0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13643	uniprotkb:A0A0S2Z6M9	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	intact:EBI-16428876	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:a0a0s2z6m9_human(display_long)|uniprotkb:FAM126A(gene name)|psi-mi:FAM126A(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466973	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR018619|refseq:XP_005249952.1|entrezgene/locuslink:84668(identity)	intact:EBI-16435564(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	rogid:BB9OGAPlTXTKfaNW+w3TSxbbHow9606	rigid:7c68waStcr0Oe7MWzEiDNd0slwg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13557-8	uniprotkb:Q13216-2	intact:EBI-11534483|ensembl:ENSP00000296402|ensembl:ENSP00000369098	intact:EBI-16466949|ensembl:ENSP00000494466|ensembl:ENSP00000502154	psi-mi:q13557-8(display_long)|uniprotkb:CAMKD(gene name synonym)|uniprotkb:CAMK2D(gene name)|psi-mi:CAMK2D(display_short)	psi-mi:q13216-2(display_long)|uniprotkb:ERCC8(gene name)|psi-mi:ERCC8(display_short)|uniprotkb:CKN1(gene name synonym)|uniprotkb:CSA(gene name synonym)|uniprotkb:Cockayne syndrome WD repeat protein CSA(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466957	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-351018(isoform-parent)|ensembl:ENSG00000145349(gene)|ensembl:ENST00000296402(transcript)|ensembl:ENST00000379773(transcript)|uniprotkb:Q13557-8(isoform-parent)|entrezgene/locuslink:817(identity)	intact:EBI-295260(isoform-parent)|uniprotkb:Q13216-2(isoform-parent)|ensembl:ENSG00000049167(gene)|ensembl:ENST00000647486(transcript)|ensembl:ENST00000675229(transcript)|entrezgene/locuslink:1161(identity)	intact:EBI-16440912(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:44T/I8JdalScCNE5Vp/H+PnfdFo9606	rogid:Lf4ue+p6QP9+CoKq1z0j6IbDzk89606	rigid:pNv+PvviwHCd/+Zooh0/L5ioDTc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96D09	uniprotkb:Q8IYU8	intact:EBI-473189|ensembl:ENSP00000339057|ensembl:ENSP00000437394|ensembl:ENSP00000437872|ensembl:ENSP00000507692|ensembl:ENSP00000508139|uniprotkb:Q8NAB4|uniprotkb:D3DXA0	intact:EBI-3197790|ensembl:ENSP00000371811|uniprotkb:Q8N0T6|uniprotkb:Q8NAX8	psi-mi:gasp2_human(display_long)|uniprotkb:GPRASP2(gene name)|psi-mi:GPRASP2(display_short)	psi-mi:micu2_human(display_long)|uniprotkb:MICU2(gene name)|psi-mi:MICU2(display_short)|uniprotkb:EF-hand domain-containing family member A1(gene name synonym)|uniprotkb:EFHA1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466933	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000158301(gene)|ensembl:ENST00000332262(transcript)|ensembl:ENST00000483720(transcript)|ensembl:ENST00000486814(transcript)|ensembl:ENST00000535209(transcript)|ensembl:ENST00000543253(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:NP_001004051.1|refseq:NP_001171803.1|refseq:NP_001171804.1|refseq:NP_001171805.1|refseq:NP_001186747.1|refseq:NP_612446.1|entrezgene/locuslink:114928(identity)	ensembl:ENSG00000165487(gene)|ensembl:ENST00000382374(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0034704"(calcium channel complex)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:1990246"(uniplex complex)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR039800|rcsb pdb:6AGH|rcsb pdb:6IIH|rcsb pdb:6K7Y|rcsb pdb:6LB7|rcsb pdb:6LB8|rcsb pdb:6LE5|rcsb pdb:6WDN|rcsb pdb:6WDO|rcsb pdb:6XJV|rcsb pdb:6XJX|rcsb pdb:6XQN|rcsb pdb:6XQO|reactome:R-HSA-8949215|reactome:R-HSA-8949664|refseq:NP_689939.1|entrezgene/locuslink:221154(identity)	intact:EBI-16439974(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aUbvpCvGto1y4Rqnri7qaKaygQ89606	rogid:qj7nAE+DvoW/RWlr4VWGSbhS6Mc9606	rigid:ksLVZyn2bja1KF48zbJW1U9k2o8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14188-5	uniprotkb:Q2Z196	intact:EBI-12181237|ensembl:ENSP00000418590|ensembl:ENSP00000420599	intact:EBI-16466898|ensembl:ENSP00000389113	psi-mi:q14188-5(display_long)|uniprotkb:TFDP2(gene name)|psi-mi:TFDP2(display_short)|uniprotkb:DP2(gene name synonym)|uniprotkb:E2F dimerization partner 2(gene name synonym)	psi-mi:q2z196_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466917	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-752268(isoform-parent)|uniprotkb:Q14188-5(isoform-parent)|ensembl:ENSG00000114126(gene)|ensembl:ENST00000467072(transcript)|ensembl:ENST00000486111(transcript)|entrezgene/locuslink:7029(identity)	ensembl:ENSG00000169016(gene)|ensembl:ENST00000421117(transcript)|entrezgene/locuslink:1876(identity)	intact:EBI-16439164(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:rdh6QA6IAPo+ksMkB9o5Kn+kKfw9606	rogid:MuHBDwxpZFl1AqkQHVebZ9XMNyc9606	rigid:ktoe5y+VJmI5vUZQvMtOqEOF09s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14186	uniprotkb:Q2Z196	intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519	intact:EBI-16466898|ensembl:ENSP00000389113	psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym)	psi-mi:q2z196_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466901	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|entrezgene/locuslink:7027(identity)	ensembl:ENSG00000169016(gene)|ensembl:ENST00000421117(transcript)|entrezgene/locuslink:1876(identity)	intact:EBI-16438111(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606	rogid:MuHBDwxpZFl1AqkQHVebZ9XMNyc9606	rigid:ZxA4JyRAfkrq/m/0W99OHp1kMYU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96EA4	uniprotkb:A0A0S2Z5X9	intact:EBI-715381|uniprotkb:Q8TEC8|uniprotkb:Q9HD44|uniprotkb:Q9NX97|uniprotkb:C9JS47|ensembl:ENSP00000265295|uniprotkb:B4E393	intact:EBI-16466729	psi-mi:spdly_human(display_long)|uniprotkb:SPDL1(gene name)|psi-mi:SPDL1(display_short)|uniprotkb:Arsenite-related gene 1 protein(gene name synonym)|uniprotkb:CCDC99(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 99(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.4A(gene name synonym)|uniprotkb:Spindle apparatus coiled-coil domain-containing protein 1(gene name synonym)	psi-mi:a0a0s2z5x9_human(display_long)|uniprotkb:DYX1C1(gene name)|psi-mi:DYX1C1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466881	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060255.3|ensembl:ENSG00000040275(gene)|ensembl:ENST00000265295(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051301"(cell division)|interpro:IPR028593|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001316570.1|dip:DIP-47296N|entrezgene/locuslink:54908(identity)	go:"GO:0003341"(cilium movement)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0043005"(neuron projection)|interpro:IPR037894|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|entrezgene/locuslink:161582(identity)	intact:EBI-16437624(see-also)|intact:EBI-16437634(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CzXKB2VOL2ZBmQjyc4vGxQ0cTnY9606	rogid:3LLU6rV0aXiXARV+8aVc7WDqFiQ9606	rigid:X13wQgydSj0ihGCODPcFtZvBg9c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P13646	uniprotkb:A0A0S2Z5X9	intact:EBI-1223876|uniprotkb:Q53G54|uniprotkb:Q6AZK5|uniprotkb:Q8N240|ensembl:ENSP00000246635	intact:EBI-16466729	psi-mi:k1c13_human(display_long)|uniprotkb:KRT13(gene name)|psi-mi:KRT13(display_short)|uniprotkb:Keratin-13(gene name synonym)|uniprotkb:Cytokeratin-13(gene name synonym)	psi-mi:a0a0s2z5x9_human(display_long)|uniprotkb:DYX1C1(gene name)|psi-mi:DYX1C1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466865	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002265.2|refseq:NP_705694.2|ensembl:ENSG00000171401(gene)|ensembl:ENST00000246635(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3860(identity)	go:"GO:0003341"(cilium movement)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0043005"(neuron projection)|interpro:IPR037894|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|entrezgene/locuslink:161582(identity)	intact:EBI-16435900(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u65zix/f6VQ+vmbfMhXWqmiERRY9606	rogid:3LLU6rV0aXiXARV+8aVc7WDqFiQ9606	rigid:mkbsRmqVDmpfjG7UGiH6tEOrU8Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P13646	uniprotkb:Q8WXU2-2	intact:EBI-1223876|uniprotkb:Q53G54|uniprotkb:Q6AZK5|uniprotkb:Q8N240|ensembl:ENSP00000246635	intact:EBI-9381887|ensembl:ENSP00000403412	psi-mi:k1c13_human(display_long)|uniprotkb:KRT13(gene name)|psi-mi:KRT13(display_short)|uniprotkb:Keratin-13(gene name synonym)|uniprotkb:Cytokeratin-13(gene name synonym)	psi-mi:q8wxu2-2(display_long)|uniprotkb:DNAAF4(gene name)|psi-mi:DNAAF4(display_short)|uniprotkb:DYX1C1(gene name synonym)|uniprotkb:Dyslexia susceptibility 1 candidate gene 1 protein(gene name synonym)|uniprotkb:EKN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466849	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002265.2|refseq:NP_705694.2|ensembl:ENSG00000171401(gene)|ensembl:ENST00000246635(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3860(identity)	ensembl:ENSG00000256061(gene)|ensembl:ENST00000448430(transcript)|uniprotkb:Q8WXU2-2(isoform-parent)|intact:EBI-2946907(isoform-parent)|entrezgene/locuslink:161582(identity)	intact:EBI-16435900(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u65zix/f6VQ+vmbfMhXWqmiERRY9606	rogid:jYtZBqy6D77KSvFPNp8nBddDD1s9606	rigid:MOOBusOlEKu1qfDAyOxYX83rDhU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UNE7	intact:EBI-16430217	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	-	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:"ccsb isoform id: dyx1c1_3"(display_short)|psi-mi:EBI-16430217(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466833	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168|entrezgene/locuslink:10273(identity)	entrezgene/locuslink:161582(identity)	intact:EBI-16435264(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	rogid:m0aEcT+ILE0RLI1nuExTVcJ+UO09606	rigid:Y7vI6BZYDvPL+DCb4s/cPbycINc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UNE7	uniprotkb:A0A0S2Z5X9	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	intact:EBI-16466729	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:a0a0s2z5x9_human(display_long)|uniprotkb:DYX1C1(gene name)|psi-mi:DYX1C1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466817	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168|entrezgene/locuslink:10273(identity)	go:"GO:0003341"(cilium movement)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0043005"(neuron projection)|interpro:IPR037894|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|entrezgene/locuslink:161582(identity)	intact:EBI-16435264(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	rogid:3LLU6rV0aXiXARV+8aVc7WDqFiQ9606	rigid:nxm4dB1aWljQHkH4QLAda5itvXk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N4Y2-3	uniprotkb:A0A0S2Z5X9	intact:EBI-11982645|ensembl:ENSP00000409256|ensembl:ENSP00000432334	intact:EBI-16466729	psi-mi:q8n4y2-3(display_long)|uniprotkb:CRACR2B(gene name)|psi-mi:CRACR2B(display_short)|uniprotkb:Calcium release-activated calcium channel regulator 2B(gene name synonym)|uniprotkb:Calcium release-activated channel regulator 2B(gene name synonym)|uniprotkb:EFCAB4A(gene name synonym)	psi-mi:a0a0s2z5x9_human(display_long)|uniprotkb:DYX1C1(gene name)|psi-mi:DYX1C1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466801	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q8N4Y2-3(isoform-parent)|intact:EBI-10267893(isoform-parent)|ensembl:ENSG00000177685(gene)|ensembl:ENST00000528542(transcript)|ensembl:ENST00000450448(transcript)|entrezgene/locuslink:283229(identity)	go:"GO:0003341"(cilium movement)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0043005"(neuron projection)|interpro:IPR037894|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|entrezgene/locuslink:161582(identity)	intact:EBI-16431201(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:76w0B5349e/QlU4aMfv4UAGek8I9606	rogid:3LLU6rV0aXiXARV+8aVc7WDqFiQ9606	rigid:YM5cviATKyPQ/l7HmKlYfbic9FM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N4Y2-3	uniprotkb:Q8WXU2-2	intact:EBI-11982645|ensembl:ENSP00000409256|ensembl:ENSP00000432334	intact:EBI-9381887|ensembl:ENSP00000403412	psi-mi:q8n4y2-3(display_long)|uniprotkb:CRACR2B(gene name)|psi-mi:CRACR2B(display_short)|uniprotkb:Calcium release-activated calcium channel regulator 2B(gene name synonym)|uniprotkb:Calcium release-activated channel regulator 2B(gene name synonym)|uniprotkb:EFCAB4A(gene name synonym)	psi-mi:q8wxu2-2(display_long)|uniprotkb:DNAAF4(gene name)|psi-mi:DNAAF4(display_short)|uniprotkb:DYX1C1(gene name synonym)|uniprotkb:Dyslexia susceptibility 1 candidate gene 1 protein(gene name synonym)|uniprotkb:EKN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466785	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q8N4Y2-3(isoform-parent)|intact:EBI-10267893(isoform-parent)|ensembl:ENSG00000177685(gene)|ensembl:ENST00000528542(transcript)|ensembl:ENST00000450448(transcript)|entrezgene/locuslink:283229(identity)	ensembl:ENSG00000256061(gene)|ensembl:ENST00000448430(transcript)|uniprotkb:Q8WXU2-2(isoform-parent)|intact:EBI-2946907(isoform-parent)|entrezgene/locuslink:161582(identity)	intact:EBI-16431201(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:76w0B5349e/QlU4aMfv4UAGek8I9606	rogid:jYtZBqy6D77KSvFPNp8nBddDD1s9606	rigid:3xkwFesfv7Klef+eJKTwerSQ4hI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:A0A0S2Z5X9	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-16466729	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:a0a0s2z5x9_human(display_long)|uniprotkb:DYX1C1(gene name)|psi-mi:DYX1C1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466769	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	go:"GO:0003341"(cilium movement)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0043005"(neuron projection)|interpro:IPR037894|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|entrezgene/locuslink:161582(identity)	intact:EBI-16430761(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:3LLU6rV0aXiXARV+8aVc7WDqFiQ9606	rigid:s15I2OfpNaW9fEoq6Gy5yhLnXvg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:Q8WXU2-2	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-9381887|ensembl:ENSP00000403412	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:q8wxu2-2(display_long)|uniprotkb:DNAAF4(gene name)|psi-mi:DNAAF4(display_short)|uniprotkb:DYX1C1(gene name synonym)|uniprotkb:Dyslexia susceptibility 1 candidate gene 1 protein(gene name synonym)|uniprotkb:EKN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466753	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	ensembl:ENSG00000256061(gene)|ensembl:ENST00000448430(transcript)|uniprotkb:Q8WXU2-2(isoform-parent)|intact:EBI-2946907(isoform-parent)|entrezgene/locuslink:161582(identity)	intact:EBI-16430761(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:jYtZBqy6D77KSvFPNp8nBddDD1s9606	rigid:gpAgk7W+1I1/WKapQoyOgrTBmlU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00471	uniprotkb:A0A0S2Z5X9	intact:EBI-949824|ensembl:ENSP00000484855|uniprotkb:B2R6C5|intact:EBI-10171392|uniprotkb:Q8IW24	intact:EBI-16466729	psi-mi:exoc5_human(display_long)|uniprotkb:Exocyst complex component Sec10(gene name synonym)|uniprotkb:EXOC5(gene name)|psi-mi:EXOC5(display_short)|uniprotkb:SEC10(gene name synonym)|uniprotkb:SEC10L1(gene name synonym)	psi-mi:a0a0s2z5x9_human(display_long)|uniprotkb:DYX1C1(gene name)|psi-mi:DYX1C1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16466737	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070367(gene)|ensembl:ENST00000621441(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904019"(epithelial cell apoptotic process)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009976(Exocyst complex component Sec10)|interpro:IPR033960|mint:O00471|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:NP_006535.1|entrezgene/locuslink:10640(identity)	go:"GO:0003341"(cilium movement)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0043005"(neuron projection)|interpro:IPR037894|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|entrezgene/locuslink:161582(identity)	intact:EBI-16430219(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UaEk0DAH+boE9+hl8z3VUUI78dM9606	rogid:3LLU6rV0aXiXARV+8aVc7WDqFiQ9606	rigid:L3uoaWobFnPAhT8VaRjD9rj+60Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:Q9BSJ6	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467286	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16439994(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:AmJaI7kgWRgy9LQxEivk42xb6D8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:Q9BSJ6	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467270	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16439080(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:HaL/t9TltJZzvmbvScc+5r7n8qo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14964	uniprotkb:A0A0S2Z3S1	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	intact:EBI-16439494	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:a0a0s2z3s1_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467321	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039684|entrezgene/locuslink:2189(identity)	intact:EBI-16433881(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:mkRCuC2B7qX+asLEBAYHJIHfdbU9606	rigid:d2VOJY77uH0qNeQW1wmIHZwKqgA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14964	uniprotkb:A0A0S2Z3W0	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	intact:EBI-16467337	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:a0a0s2z3w0_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467340	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	entrezgene/locuslink:2189(identity)	intact:EBI-16433881(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:i9+i1HUZHQw91ZxR7+Lqa5h8WF09606	rigid:GVDtFl6K+6dXXDgaa3MvUwGU8Q8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478	uniprotkb:A0A0S2Z3S1	intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016	intact:EBI-16439494	psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)	psi-mi:a0a0s2z3s1_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467356	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity)	go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039684|entrezgene/locuslink:2189(identity)	intact:EBI-16438051(see-also)|intact:EBI-16438061(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606	rogid:mkRCuC2B7qX+asLEBAYHJIHfdbU9606	rigid:sxDBZCrF3FDKBOm77xgOYhVvAJM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478	uniprotkb:A0A0S2Z3W0	intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016	intact:EBI-16467337	psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)	psi-mi:a0a0s2z3w0_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467373	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity)	entrezgene/locuslink:2189(identity)	intact:EBI-16438051(see-also)|intact:EBI-16438061(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606	rogid:i9+i1HUZHQw91ZxR7+Lqa5h8WF09606	rigid:ASs+B/85HSdSkw7dgRt5I8l2tI4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:A0A0S2Z3S1	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-16439494	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:a0a0s2z3s1_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467390	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039684|entrezgene/locuslink:2189(identity)	intact:EBI-16439809(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:mkRCuC2B7qX+asLEBAYHJIHfdbU9606	rigid:udqlk9foab/G3FXs98eGQSjfoJI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:A0A0S2Z3W0	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-16467337	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:a0a0s2z3w0_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467406	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	entrezgene/locuslink:2189(identity)	intact:EBI-16439809(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:i9+i1HUZHQw91ZxR7+Lqa5h8WF09606	rigid:Lriz4YAhPWNVlJipgQsP8YDPb2k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15645	uniprotkb:Q9NRD0	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	intact:EBI-11615366|uniprotkb:B2RB40|uniprotkb:D3DP41|uniprotkb:G5E9Z0|uniprotkb:Q6UWN4|uniprotkb:Q8IWE1|uniprotkb:Q9NRP5|uniprotkb:Q9UKC4|ensembl:ENSP00000377280	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:fbx8_human(display_long)|uniprotkb:FBXO8(gene name)|psi-mi:FBXO8(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBX8(gene name synonym)|uniprotkb:DC10(orf name)|uniprotkb:UNQ1877/PRO4320(orf name)|uniprotkb:F-box/SEC7 protein FBS(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467422	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P|entrezgene/locuslink:9319(identity)	refseq:NP_036312.2|ensembl:ENSG00000164117(gene)|ensembl:ENST00000393674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR023394|interpro:IPR035999|interpro:IPR036047|entrezgene/locuslink:26269(identity)	intact:EBI-16434724(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	rogid:iw1wQu/WnQC2vnge/KH840EAPr89606	rigid:lbiO5UVLUdwL3MTUOM8DxO5IYCw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:Q9BSJ6	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-2568609|uniprotkb:Q96CT4|uniprotkb:Q9NVV1|uniprotkb:Q9NWB5|intact:EBI-16428888|ensembl:ENSP00000250056	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:pimre_human(display_long)|uniprotkb:PICALM-interacting mitotic regulator(gene name synonym)|uniprotkb:PIMREG(gene name)|psi-mi:PIMREG(display_short)|uniprotkb:CALM-interactor expressed in thymus and spleen(gene name synonym)|uniprotkb:CATS(gene name synonym)|uniprotkb:FAM64A(gene name synonym)|uniprotkb:RCS1(gene name synonym)|uniprotkb:Regulator of chromosome segregation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467302	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	refseq:NP_001182157.1|refseq:NP_061886.2|dip:DIP-56370N|ensembl:ENSG00000129195(gene)|ensembl:ENST00000250056(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009932(Protein of unknown function DUF1466)|entrezgene/locuslink:54478(identity)	intact:EBI-16440764(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:BLU00PQAlRtdcBQW2AB7nRFR+iw9606	rigid:veDnZvJLUXdys9unRCLGl4QZc2A	true	sufficient binding region:32-313	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:O14964	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467834	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	intact:EBI-16431864(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rigid:9rOFVAZ6zJQVQJ3FnYuf7dHFnuQ	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:Q8WW76	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-16467458	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:q8ww76_human(display_long)|uniprotkb:FGA(gene name)|psi-mi:FGA(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467470	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	go:"GO:0051258"(protein polymerization)|go:"GO:0030168"(platelet activation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005577"(fibrinogen complex)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR037579|entrezgene/locuslink:2243(identity)	intact:EBI-16439092(see-also)|intact:EBI-16439104(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:KyNpb3Z1gdvzVwZ5muhihBKkF249606	rigid:tRSNnZlta/WnIl+7vG2U6Rcnb5Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:A0A0S2Z3E8	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-16439506	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:a0a0s2z3e8_human(display_long)|uniprotkb:FGA(gene name)|psi-mi:FGA(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467487	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	go:"GO:0005102"(signaling receptor binding)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0030168"(platelet activation)|go:"GO:0051258"(protein polymerization)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR037579|entrezgene/locuslink:2243(identity)	intact:EBI-16439092(see-also)|intact:EBI-16439104(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:SYq0A8PukG7MmEnVdnJftwnVatk9606	rigid:7amqe5BJlpz21IIHbBcf84MkwbM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:Q8WW76	intact:EBI-16439278	intact:EBI-16467458	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:q8ww76_human(display_long)|uniprotkb:FGA(gene name)|psi-mi:FGA(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467504	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	go:"GO:0051258"(protein polymerization)|go:"GO:0030168"(platelet activation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005577"(fibrinogen complex)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR037579|entrezgene/locuslink:2243(identity)	intact:EBI-16439517(see-also)|intact:EBI-16439527(see-also)|intact:EBI-16439537(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:KyNpb3Z1gdvzVwZ5muhihBKkF249606	rigid:iHPGYBhNr/M8cpcqGe5kGV1RIKA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95273	uniprotkb:P07954	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-1050358|uniprotkb:B1ANK7|ensembl:ENSP00000355518	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:fumh_human(display_long)|uniprotkb:FH(gene name)|psi-mi:FH(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467522	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	refseq:NP_000134.2|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000362(Fumarate lyase)|interpro:IPR005677(Fumarate hydratase, class II)|ensembl:ENSG00000091483(gene)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR018951|ensembl:ENST00000366560(transcript)|interpro:IPR020557|interpro:IPR022761|go:"GO:0000050"(urea cycle)|interpro:IPR024083|mint:P07954|rcsb pdb:3E04|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|rcsb pdb:5D6B|go:"GO:0000821"(regulation of arginine metabolic process)|rcsb pdb:5UPP|rcsb pdb:6EBT|rcsb pdb:6V8F|rcsb pdb:6VBE|go:"GO:0004333"(fumarate hydratase activity)|reactome:R-HSA-71403|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|dip:DIP-46920N|entrezgene/locuslink:2271(identity)	intact:EBI-16428911(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:Jukx6wt0vi49nxgaTzdz5x1Q2Mc9606	rigid:bbpYItEBprS5Gc3uLow0s9CPNXg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95273	uniprotkb:A0A0S2Z4H0	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-16467538	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:a0a0s2z4h0_human(display_long)|uniprotkb:FH(gene name)|psi-mi:FH(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467552	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	go:"GO:0004333"(fumarate hydratase activity)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|interpro:IPR005677(Fumarate hydratase, class II)|interpro:IPR024083|interpro:IPR018951|interpro:IPR022761|interpro:IPR008948(L-Aspartase-like)|entrezgene/locuslink:2271(identity)	intact:EBI-16428911(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:ILOCbSyaw1/FI9WqVHCYNaKIB6o9606	rigid:d5Xy2RDBdtkkdwxkRf61SOX8d9A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:Q99259	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-743184|ensembl:ENSP00000350928|uniprotkb:Q53TQ7|uniprotkb:Q9BU91|uniprotkb:Q9UHH4|uniprotkb:Q49AK1	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:dce1_human(display_long)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short)|uniprotkb:GAD(gene name synonym)|uniprotkb:GAD67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467568	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	refseq:NP_000808.2|refseq:NP_038473.2|ensembl:ENSG00000128683(gene)|ensembl:ENST00000358196(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0018352"(protein-pyridoxal-5-phosphate linkage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|mint:Q99259|rcsb pdb:2OKJ|rcsb pdb:3VP6|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927|refseq:XP_011509224.1|refseq:XP_005246501.1|refseq:XP_016859245.1|refseq:XP_016859247.1|dip:DIP-29292N|entrezgene/locuslink:2571(identity)	intact:EBI-16430773(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:tFlqx11D9m3HofJUdpZynm2jKIQ9606	rigid:6yqsQ8P7ioS1J5/wXfT8brutlfo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	intact:EBI-16467584	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	-	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467587	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16430773(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:cyNJsKXk1cCm2d7/hPh83QHFXrU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15654	uniprotkb:Q99259	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	intact:EBI-743184|ensembl:ENSP00000350928|uniprotkb:Q53TQ7|uniprotkb:Q9BU91|uniprotkb:Q9UHH4|uniprotkb:Q49AK1	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:dce1_human(display_long)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short)|uniprotkb:GAD(gene name synonym)|uniprotkb:GAD67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467603	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	refseq:NP_000808.2|refseq:NP_038473.2|ensembl:ENSG00000128683(gene)|ensembl:ENST00000358196(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0018352"(protein-pyridoxal-5-phosphate linkage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|mint:Q99259|rcsb pdb:2OKJ|rcsb pdb:3VP6|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927|refseq:XP_011509224.1|refseq:XP_005246501.1|refseq:XP_016859245.1|refseq:XP_016859247.1|dip:DIP-29292N|entrezgene/locuslink:2571(identity)	intact:EBI-16434433(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:tFlqx11D9m3HofJUdpZynm2jKIQ9606	rigid:99wCOpsohF+jq4jLhPfVr08LoqI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15654	intact:EBI-16467584	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	-	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467619	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16434433(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:hVidg71t0Q6qfqDEBP7oNt3r2jc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	intact:EBI-16467584	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	-	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467635	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16436031(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:Rf3FBuXC3qc6TlA7io6rQ9ycVqA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15323	uniprotkb:Q99259	intact:EBI-948001|uniprotkb:Q9UE12|ensembl:ENSP00000251645|ensembl:ENSP00000460739	intact:EBI-743184|ensembl:ENSP00000350928|uniprotkb:Q53TQ7|uniprotkb:Q9BU91|uniprotkb:Q9UHH4|uniprotkb:Q49AK1	psi-mi:k1h1_human(display_long)|uniprotkb:Hair keratin, type I Ha1(gene name synonym)|uniprotkb:Keratin-31(gene name synonym)|uniprotkb:KRT31(gene name)|psi-mi:KRT31(display_short)|uniprotkb:HHA1(gene name synonym)|uniprotkb:HKA1(gene name synonym)|uniprotkb:KRTHA1(gene name synonym)	psi-mi:dce1_human(display_long)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short)|uniprotkb:GAD(gene name synonym)|uniprotkb:GAD67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467651	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002268.2|ensembl:ENSG00000094796(gene)|ensembl:ENSG00000262993(gene)|ensembl:ENST00000251645(transcript)|ensembl:ENST00000573281(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3881(identity)	refseq:NP_000808.2|refseq:NP_038473.2|ensembl:ENSG00000128683(gene)|ensembl:ENST00000358196(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0018352"(protein-pyridoxal-5-phosphate linkage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|mint:Q99259|rcsb pdb:2OKJ|rcsb pdb:3VP6|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927|refseq:XP_011509224.1|refseq:XP_005246501.1|refseq:XP_016859245.1|refseq:XP_016859247.1|dip:DIP-29292N|entrezgene/locuslink:2571(identity)	intact:EBI-16436605(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ur97LEvtqaqu3wh7iaX4HhN163k9606	rogid:tFlqx11D9m3HofJUdpZynm2jKIQ9606	rigid:IBLUcybnTRx7sP3L7MDdB5238as	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15323	intact:EBI-16467584	intact:EBI-948001|uniprotkb:Q9UE12|ensembl:ENSP00000251645|ensembl:ENSP00000460739	-	psi-mi:k1h1_human(display_long)|uniprotkb:Hair keratin, type I Ha1(gene name synonym)|uniprotkb:Keratin-31(gene name synonym)|uniprotkb:KRT31(gene name)|psi-mi:KRT31(display_short)|uniprotkb:HHA1(gene name synonym)|uniprotkb:HKA1(gene name synonym)|uniprotkb:KRTHA1(gene name synonym)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467667	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002268.2|ensembl:ENSG00000094796(gene)|ensembl:ENSG00000262993(gene)|ensembl:ENST00000251645(transcript)|ensembl:ENST00000573281(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3881(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16436605(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ur97LEvtqaqu3wh7iaX4HhN163k9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:2Oao7SqotMIMaVpKfs0gAU7+oSc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q969L2	intact:EBI-16467584	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	-	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467683	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240|entrezgene/locuslink:114569(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16437245(see-also)|intact:EBI-16437255(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:W+D2Ix09eBLMHyidvMSomz9DasM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6RW13-2	intact:EBI-16467584	intact:EBI-11522760|ensembl:ENSP00000365816	-	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467700	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16439114(see-also)|intact:EBI-16439124(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:bx7WKUrui4ezD7LUl33iICFldWU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96DZ9-2	intact:EBI-16467584	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	-	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467717	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16440004(see-also)|intact:EBI-16440014(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:mmJgBRmD8pdsbpHSBLpzc/+oA9c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYR7	uniprotkb:Q99259	intact:EBI-751260|ensembl:ENSP00000375429|ensembl:ENSP00000459215	intact:EBI-743184|ensembl:ENSP00000350928|uniprotkb:Q53TQ7|uniprotkb:Q9BU91|uniprotkb:Q9UHH4|uniprotkb:Q49AK1	psi-mi:kra32_human(display_long)|uniprotkb:Keratin-associated protein 3.2(gene name synonym)|uniprotkb:High sulfur keratin-associated protein 3.2(gene name synonym)|uniprotkb:KRTAP3-2(gene name)|psi-mi:KRTAP3-2(display_short)|uniprotkb:KAP3.2(gene name synonym)|uniprotkb:KRTAP3.2(gene name synonym)	psi-mi:dce1_human(display_long)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short)|uniprotkb:GAD(gene name synonym)|uniprotkb:GAD67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467734	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114165.1|ensembl:ENSG00000212900(gene)|ensembl:ENSG00000263296(gene)|ensembl:ENST00000391587(transcript)|ensembl:ENST00000575409(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR007659(Keratin, high-sulphur matrix protein)|reactome:R-HSA-6805567|entrezgene/locuslink:83897(identity)	refseq:NP_000808.2|refseq:NP_038473.2|ensembl:ENSG00000128683(gene)|ensembl:ENST00000358196(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0018352"(protein-pyridoxal-5-phosphate linkage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|mint:Q99259|rcsb pdb:2OKJ|rcsb pdb:3VP6|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927|refseq:XP_011509224.1|refseq:XP_005246501.1|refseq:XP_016859245.1|refseq:XP_016859247.1|dip:DIP-29292N|entrezgene/locuslink:2571(identity)	intact:EBI-16440206(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2AFUGT7g1vlyF9kv3x5NYu/bv9c9606	rogid:tFlqx11D9m3HofJUdpZynm2jKIQ9606	rigid:Aa7DC819tqvKCHa/IP8v5fp2gL0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYR7	intact:EBI-16467584	intact:EBI-751260|ensembl:ENSP00000375429|ensembl:ENSP00000459215	-	psi-mi:kra32_human(display_long)|uniprotkb:Keratin-associated protein 3.2(gene name synonym)|uniprotkb:High sulfur keratin-associated protein 3.2(gene name synonym)|uniprotkb:KRTAP3-2(gene name)|psi-mi:KRTAP3-2(display_short)|uniprotkb:KAP3.2(gene name synonym)|uniprotkb:KRTAP3.2(gene name synonym)	psi-mi:"ccsb isoform id: gad1_3"(display_short)|psi-mi:EBI-16467584(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467750	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114165.1|ensembl:ENSG00000212900(gene)|ensembl:ENSG00000263296(gene)|ensembl:ENST00000391587(transcript)|ensembl:ENST00000575409(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR007659(Keratin, high-sulphur matrix protein)|reactome:R-HSA-6805567|entrezgene/locuslink:83897(identity)	entrezgene/locuslink:2571(identity)	intact:EBI-16440206(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2AFUGT7g1vlyF9kv3x5NYu/bv9c9606	rogid:fNm5SveXKCMEljahMF30mQOgf7Y9606	rigid:O2V/Q2pdzf2/oioWEp78lcnPGWs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:Q9BRX5	intact:EBI-16439278	intact:EBI-2857315|uniprotkb:B2RDP3|uniprotkb:Q9H870|uniprotkb:E9PB21|ensembl:ENSP00000318196	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:psf3_human(display_long)|uniprotkb:GINS3(gene name)|psi-mi:GINS3(display_short)|uniprotkb:PSF3(gene name synonym)|uniprotkb:GINS complex subunit 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467766	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	refseq:NP_001119601.1|refseq:NP_001119602.1|refseq:NP_073607.2|dip:DIP-29333N|ensembl:ENSG00000181938(gene)|ensembl:ENST00000318129(transcript)|go:"GO:0000811"(GINS complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|mint:Q9BRX5|rcsb pdb:2E9X|rcsb pdb:2EHO|rcsb pdb:2Q9Q|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176974|entrezgene/locuslink:64785(identity)	intact:EBI-16439547(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:3anXwRLIwu/t1G1v+P1yzhh7QqA9606	rigid:2gdXs5udza36qzmAJeEm2Eys5Xk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P49407	uniprotkb:A0A0S2Z5F2	intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581	intact:EBI-16440982	psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym)	psi-mi:a0a0s2z5f2_human(display_long)|uniprotkb:GNMT(gene name)|psi-mi:GNMT(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467782	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N|entrezgene/locuslink:408(identity)	interpro:IPR041698|go:"GO:0017174"(glycine N-methyltransferase activity)|go:"GO:0032259"(methylation)|refseq:NP_001305794.1|interpro:IPR014369(Glycine N-methyltransferase)|interpro:IPR029063|entrezgene/locuslink:27232(identity)	intact:EBI-16434180(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: GNMT_3 expression is provided in figureS2H."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606	rogid:fJAMGRDcSZgsh1BDT1O6WFgX1mc9606	rigid:2sSYsEZmwNO2BNdo9alDQe6W8K8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P49407	uniprotkb:A0A0S2Z594	intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581	intact:EBI-16467798	psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym)	psi-mi:a0a0s2z594_human(display_long)|uniprotkb:GNMT(gene name)|psi-mi:GNMT(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467801	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N|entrezgene/locuslink:408(identity)	interpro:IPR041698|go:"GO:0017174"(glycine N-methyltransferase activity)|go:"GO:0032259"(methylation)|interpro:IPR014369(Glycine N-methyltransferase)|interpro:IPR029063|entrezgene/locuslink:27232(identity)	intact:EBI-16434180(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: GNMT_4 expression is provided in figureS2H."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606	rogid:ZSlpNMZa5lzAcw3yv60jmgcjt3Y9606	rigid:2WNPXbVX5T+HAHqOJux1Jv3PGkc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14749	uniprotkb:A0A0S2Z594	intact:EBI-744239|uniprotkb:Q9NNZ1|uniprotkb:Q9NS24|uniprotkb:Q5T8W2|ensembl:ENSP00000361894	intact:EBI-16467798	psi-mi:gnmt_human(display_long)|uniprotkb:GNMT(gene name)|psi-mi:GNMT(display_short)	psi-mi:a0a0s2z594_human(display_long)|uniprotkb:GNMT(gene name)|psi-mi:GNMT(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467817	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061833.1|refseq:NP_001305794.1|ensembl:ENSG00000124713(gene)|ensembl:ENST00000372808(transcript)|go:"GO:0005542"(folic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016594"(glycine binding)|go:"GO:0017174"(glycine N-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046498"(S-adenosylhomocysteine metabolic process)|go:"GO:0046500"(S-adenosylmethionine metabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1901052"(sarcosine metabolic process)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR014369(Glycine N-methyltransferase)|interpro:IPR029063|interpro:IPR041698|rcsb pdb:1R74|rcsb pdb:2AZT|reactome:R-HSA-2408508|reactome:R-HSA-389661|entrezgene/locuslink:27232(identity)	interpro:IPR041698|go:"GO:0017174"(glycine N-methyltransferase activity)|go:"GO:0032259"(methylation)|interpro:IPR014369(Glycine N-methyltransferase)|interpro:IPR029063|entrezgene/locuslink:27232(identity)	intact:EBI-16440972(see-also)|intact:EBI-16440990(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: GNMT_4 expression is provided in figureS2H."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:noj0nCgjJ1Dq079ycrwAu30a4AU9606	rogid:ZSlpNMZa5lzAcw3yv60jmgcjt3Y9606	rigid:JYTJqL24YSNOjE9kRFD3CkdMOxk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:A0A0S2Z4Q4	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-16429135	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467853	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16433353(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:8k3uD5Pywqm2uWZisXqdSyH3Uss	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYM8	uniprotkb:O14964	intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467869	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N|entrezgene/locuslink:10616(identity)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	intact:EBI-16433452(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rigid:Z0mzCZAg9K8CUJJB74SEBYnhugY	true	sufficient binding region:11-510	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HD26-2	uniprotkb:Q8WVV9	intact:EBI-11102276|ensembl:ENSP00000052569	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468261	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16430618(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:kGjltN2MVv03cF1uqLykBg3V5Aw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q05519-2	uniprotkb:A0A0S2Z5U3	intact:EBI-11975029|ensembl:ENSP00000359989	intact:EBI-16468000	psi-mi:q05519-2(display_long)|uniprotkb:SRSF11(gene name)|psi-mi:SRSF11(display_short)|uniprotkb:Arginine-rich 54 kDa nuclear protein(gene name synonym)|uniprotkb:SFRS11(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 11(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468181	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q05519-2(isoform-parent)|intact:EBI-1051785(isoform-parent)|ensembl:ENSG00000116754(gene)|ensembl:ENST00000370951(transcript)|entrezgene/locuslink:9295(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16430291(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:jNkAVUlnfT59fvbzTBQJUfR7lxY9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:4AiLxzgWVls10+YcOD1fg0n9uFY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-10177480	uniprotkb:A0A0S2Z5U3	-	intact:EBI-16468000	psi-mi:clone_11897(display_short)|psi-mi:EBI-10177480(display_long)|uniprotkb:Cerebral protein 11(gene name synonym)|uniprotkb:KIAA0481(gene name synonym)|uniprotkb:hucep-11(orf name)|uniprotkb:TMCC2(gene name)|psi-mi:TMCC2(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468245	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:O75069-4(see-also)|intact:EBI-12696212(see-also)|intact:EBI-726731(see-also)|entrezgene/locuslink:9911(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16430482(see-also)	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/22	rogid:hIJ1KAUaIyjszZvvmcTXV6Nox8o9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:taV4yOTGqu/l3SW3S1dG/UyjoJg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-10177480	uniprotkb:Q8WVV9	-	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:clone_11897(display_short)|psi-mi:EBI-10177480(display_long)|uniprotkb:Cerebral protein 11(gene name synonym)|uniprotkb:KIAA0481(gene name synonym)|uniprotkb:hucep-11(orf name)|uniprotkb:TMCC2(gene name)|psi-mi:TMCC2(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468229	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:O75069-4(see-also)|intact:EBI-12696212(see-also)|intact:EBI-726731(see-also)|entrezgene/locuslink:9911(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16430482(see-also)	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/22	rogid:hIJ1KAUaIyjszZvvmcTXV6Nox8o9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:Y5FiPLiIWcjo4UtXHLf/Fscbcqk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VWX1	uniprotkb:A0A0S2Z5U3	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	intact:EBI-16468000	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468213	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468|entrezgene/locuslink:202559(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16430321(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:AMMpyTpv9rdO35EP/DHt2T5v50A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VWX1	uniprotkb:Q8WVV9	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468197	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468|entrezgene/locuslink:202559(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16430321(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:9JNd1rehkJDXrrhJ17mDDGcKbMM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:A0A0S2Z5U3	-	intact:EBI-16468000	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468309	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16430630(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:jAmvjM4nVl1VmNGE/PwQxF+MT3c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:Q8WVV9	-	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468293	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16430630(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:puQ79Hiivev1ih6wdghxHul/fNE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478-2	uniprotkb:A0A0S2Z4Q4	intact:EBI-16433586|ensembl:ENSP00000487973	intact:EBI-16429135	psi-mi:o75478-2(display_long)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467888	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000277104(gene)|ensembl:ENST00000633584(transcript)|intact:EBI-742268(isoform-parent)|uniprotkb:O75478-2(isoform-parent)|entrezgene/locuslink:6871(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16433593(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JHWBurvcalqBr39eeJPqONrU9GM9606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:uFKRuFxYi01Y3VOA7YXm8lp+n3g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:A0A0S2Z4Q4	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-16429135	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467904	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16433603(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:WHrWwh7FiczVvwI6zrwt2IPvSUA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14525	uniprotkb:A0A0S2Z4Q4	intact:EBI-1049638|uniprotkb:O76010|ensembl:ENSP00000251646|ensembl:ENSP00000459509	intact:EBI-16429135	psi-mi:kt33b_human(display_long)|uniprotkb:KRTHA3B(gene name synonym)|uniprotkb:Hair keratin, type I Ha3-II(gene name synonym)|uniprotkb:Keratin-33B(gene name synonym)|uniprotkb:KRT33B(gene name)|psi-mi:KRT33B(display_short)|uniprotkb:HHA3-II(gene name synonym)|uniprotkb:HKA3B(gene name synonym)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467920	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002270.1|ensembl:ENSG00000131738(gene)|ensembl:ENSG00000263012(gene)|ensembl:ENST00000251646(transcript)|ensembl:ENST00000570596(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007568"(aging)|go:"GO:0042633"(hair cycle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:Q14525|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3884(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16437963(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:TDqltAJBdpwMGaQsl0Lznc8Y7Ns9606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:iTmUFxCpN+QYKWQHSszaOTC29QM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96HW7-2	uniprotkb:A0A0S2Z4Q4	intact:EBI-16438029|ensembl:ENSP00000433644	intact:EBI-16429135	psi-mi:q96hw7-2(display_long)|uniprotkb:INTS4(gene name)|psi-mi:INTS4(display_short)|uniprotkb:MSTP093(orf name)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467936	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5663129(isoform-parent)|ensembl:ENSG00000149262(gene)|ensembl:ENST00000529807(transcript)|entrezgene/locuslink:92105(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16438035(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:NDpAzVmN+obi0a3tSH56T4uc2UM9606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:wQcqYNc2k+/uf/q4XzMBRgqh8r0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96MT8-3	uniprotkb:A0A0S2Z4Q4	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	intact:EBI-16429135	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467952	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16438121(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:3vrh/6mkb2kr3zGZnXJUEFa8+ug	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:A0A0S2Z4Q4	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-16429135	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467968	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16439819(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:iRxgkJfqsteoQL1YZwOGUSBtMXs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y577	uniprotkb:A0A0S2Z4Q4	intact:EBI-743894|uniprotkb:B4DVJ2|uniprotkb:Q5VST8|ensembl:ENSP00000295033|ensembl:ENSP00000355658|ensembl:ENSP00000355659|ensembl:ENSP00000493891|ensembl:ENSP00000495842|ensembl:ENSP00000496098	intact:EBI-16429135	psi-mi:tri17_human(display_long)|uniprotkb:Testis RING finger protein(gene name synonym)|uniprotkb:RING finger protein 16(gene name synonym)|uniprotkb:TRIM17(gene name)|psi-mi:TRIM17(display_short)|uniprotkb:RBCC(gene name synonym)|uniprotkb:RNF16(gene name synonym)|uniprotkb:TERF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 17(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM17(gene name synonym)	psi-mi:a0a0s2z4q4_human(display_long)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16467984	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162931(gene)|ensembl:ENSG00000285344(gene)|refseq:NP_001020111.1|refseq:NP_001128327.1|refseq:NP_057186.1|refseq:XP_011542511.1|refseq:XP_011542512.1|refseq:XP_006711842.1|ensembl:ENST00000295033(transcript)|ensembl:ENST00000366697(transcript)|ensembl:ENST00000366698(transcript)|ensembl:ENST00000645562(transcript)|ensembl:ENST00000645958(transcript)|ensembl:ENST00000647385(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045087"(innate immune response)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032918|interpro:IPR035687|interpro:IPR043136|reactome:R-HSA-877300|entrezgene/locuslink:51127(identity)	go:"GO:0016301"(kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR008942(ENTH/VHS)|interpro:IPR024641|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR002014(VHS)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:9146(identity)	intact:EBI-16440922(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:pXiCDkeNMtq9icQduH4MSCM6vSQ9606	rogid:XhaP4mBwH/0sRF59j/8QutLXj+k9606	rigid:FN6B2ICEvGKQvUflEsOsIx+PV3c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:A0A0S2Z5U3	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-16468000	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468015	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16428940(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:C3+DAP61qWkmsKW7qdEia5E3PP4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	uniprotkb:Q8WVV9	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468031	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16429161(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:yQrmAXR0+cabf1LbAvJ9XPbEuEA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	uniprotkb:A0A0S2Z5U3	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	intact:EBI-16468000	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468047	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16429161(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:mgHL3AZ8JlVKhDrFW4hFKutdwFU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:Q8WVV9	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468063	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16429456(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:MBygL8ZauycaqUMbtiMqNNatzGg	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:A0A0S2Z5U3	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-16468000	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468082	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16429456(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:yZy0KIvqvkVjOwiijlWFnVPgnYM	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P12757	uniprotkb:Q8WVV9	intact:EBI-2902468|uniprotkb:A6NGT1|uniprotkb:O00464|uniprotkb:P12756|uniprotkb:Q07501|uniprotkb:B4DT50|ensembl:ENSP00000259119|ensembl:ENSP00000415243	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:skil_human(display_long)|uniprotkb:SKIL(gene name)|psi-mi:SKIL(display_short)|uniprotkb:SNO(gene name synonym)|uniprotkb:Ski-related protein(gene name synonym)|uniprotkb:Ski-related oncogene(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138569.1|refseq:NP_001138570.1|refseq:NP_005405.2|refseq:NP_001234937.1|refseq:XP_005247778.1|ensembl:ENSG00000136603(gene)|ensembl:ENST00000259119(transcript)|ensembl:ENST00000458537(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016605"(PML body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070848"(response to growth factor)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028373|interpro:IPR037000|rcsb pdb:3EQ5|rcsb pdb:5C4V|reactome:R-HSA-2173795|refseq:XP_006713798.1|dip:DIP-42138N|entrezgene/locuslink:6498(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16429642(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CktHHQJKOG+DaY5zwy1U+2YeTmw9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:r6fHbN0gYd+dtTJnxocgCeAez9I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P12757	uniprotkb:A0A0S2Z5U3	intact:EBI-2902468|uniprotkb:A6NGT1|uniprotkb:O00464|uniprotkb:P12756|uniprotkb:Q07501|uniprotkb:B4DT50|ensembl:ENSP00000259119|ensembl:ENSP00000415243	intact:EBI-16468000	psi-mi:skil_human(display_long)|uniprotkb:SKIL(gene name)|psi-mi:SKIL(display_short)|uniprotkb:SNO(gene name synonym)|uniprotkb:Ski-related protein(gene name synonym)|uniprotkb:Ski-related oncogene(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468117	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138569.1|refseq:NP_001138570.1|refseq:NP_005405.2|refseq:NP_001234937.1|refseq:XP_005247778.1|ensembl:ENSG00000136603(gene)|ensembl:ENST00000259119(transcript)|ensembl:ENST00000458537(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016605"(PML body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070848"(response to growth factor)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028373|interpro:IPR037000|rcsb pdb:3EQ5|rcsb pdb:5C4V|reactome:R-HSA-2173795|refseq:XP_006713798.1|dip:DIP-42138N|entrezgene/locuslink:6498(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16429642(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CktHHQJKOG+DaY5zwy1U+2YeTmw9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:o0PM1nakqNixz9cifbKHx9Tj/Zg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q8WVV9	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468133	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16429927(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:IF2wLf8qhyWMxYoj7vQplA0BgTI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:A0A0S2Z5U3	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16468000	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468149	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16429927(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:neNI/e6ct3YS3jVzT6XWIQyDcdA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q05519-2	uniprotkb:Q8WVV9	intact:EBI-11975029|ensembl:ENSP00000359989	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:q05519-2(display_long)|uniprotkb:SRSF11(gene name)|psi-mi:SRSF11(display_short)|uniprotkb:Arginine-rich 54 kDa nuclear protein(gene name synonym)|uniprotkb:SFRS11(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 11(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468165	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q05519-2(isoform-parent)|intact:EBI-1051785(isoform-parent)|ensembl:ENSG00000116754(gene)|ensembl:ENST00000370951(transcript)|entrezgene/locuslink:9295(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16430291(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:jNkAVUlnfT59fvbzTBQJUfR7lxY9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:BjXLWChezvd/7cAA1Pixi4rMixA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HD26-2	uniprotkb:A0A0S2Z5U3	intact:EBI-11102276|ensembl:ENSP00000052569	intact:EBI-16468000	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468277	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16430618(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:dY/uU8Z314KZ5VUZ1icJ+TKFvyY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:A0A0S2Z5U3	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-16468000	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468905	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16437783(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:/Bv7AVHjU5B2AaXT8/yW148GWZI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:Q8WVV9	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468889	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16437783(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:5ySNBJRGIAb8rGX7jYnr6qDFFvA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16437007	uniprotkb:A0A0S2Z5U3	-	intact:EBI-16468000	psi-mi:"ccsb orf id: 56711"(display_short)|psi-mi:EBI-16437007(display_long)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468873	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:386682(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16437039(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TyoW1FiRm0mclGU0YkO2RWsRGo9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:PQ+QADIonnpKZ0gCIaZndEbUpEk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16437007	uniprotkb:Q8WVV9	-	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:"ccsb orf id: 56711"(display_short)|psi-mi:EBI-16437007(display_long)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468857	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:386682(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16437039(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TyoW1FiRm0mclGU0YkO2RWsRGo9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:vgNMG+uKo1MZ8xR04No929MiU5w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	uniprotkb:A0A0S2Z5U3	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	intact:EBI-16468000	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468841	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16436987(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:KEjQcBgeCQrp2HhZ7aNl785Noy8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	uniprotkb:Q8WVV9	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468825	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16436987(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:4lmEAxuhH+R1cx+BJ4y3YRzHN90	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IZU0	uniprotkb:A0A0S2Z5U3	intact:EBI-10175124|uniprotkb:Q8N7Z8|uniprotkb:Q0IJ68|ensembl:ENSP00000318716|ensembl:ENSP00000412606|ensembl:ENSP00000431456|ensembl:ENSP00000498495	intact:EBI-16468000	psi-mi:fam9b_human(display_long)|uniprotkb:FAM9B(gene name)|psi-mi:FAM9B(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468809	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_995321.1|refseq:XP_011543766.1|ensembl:ENSG00000177138(gene)|ensembl:ENST00000327220(transcript)|ensembl:ENST00000428477(transcript)|ensembl:ENST00000472522(transcript)|ensembl:ENST00000651278(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|entrezgene/locuslink:171483(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16436779(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:tEJbrpO7KWcw7izp1VJ+5q6Xces9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:09w7q405In8KRnkaYV68il1z010	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IZU0	uniprotkb:Q8WVV9	intact:EBI-10175124|uniprotkb:Q8N7Z8|uniprotkb:Q0IJ68|ensembl:ENSP00000318716|ensembl:ENSP00000412606|ensembl:ENSP00000431456|ensembl:ENSP00000498495	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:fam9b_human(display_long)|uniprotkb:FAM9B(gene name)|psi-mi:FAM9B(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468793	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_995321.1|refseq:XP_011543766.1|ensembl:ENSG00000177138(gene)|ensembl:ENST00000327220(transcript)|ensembl:ENST00000428477(transcript)|ensembl:ENST00000472522(transcript)|ensembl:ENST00000651278(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|entrezgene/locuslink:171483(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16436779(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:tEJbrpO7KWcw7izp1VJ+5q6Xces9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:1AlS2kOi8iFHCW/E2SJML65Vnl4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15323	uniprotkb:A0A0S2Z5U3	intact:EBI-948001|uniprotkb:Q9UE12|ensembl:ENSP00000251645|ensembl:ENSP00000460739	intact:EBI-16468000	psi-mi:k1h1_human(display_long)|uniprotkb:Hair keratin, type I Ha1(gene name synonym)|uniprotkb:Keratin-31(gene name synonym)|uniprotkb:KRT31(gene name)|psi-mi:KRT31(display_short)|uniprotkb:HHA1(gene name synonym)|uniprotkb:HKA1(gene name synonym)|uniprotkb:KRTHA1(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468777	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002268.2|ensembl:ENSG00000094796(gene)|ensembl:ENSG00000262993(gene)|ensembl:ENST00000251645(transcript)|ensembl:ENST00000573281(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3881(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16436615(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ur97LEvtqaqu3wh7iaX4HhN163k9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:HGdGLl/dTfIGqF+O82zHZx2o7hQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15323	uniprotkb:Q8WVV9	intact:EBI-948001|uniprotkb:Q9UE12|ensembl:ENSP00000251645|ensembl:ENSP00000460739	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:k1h1_human(display_long)|uniprotkb:Hair keratin, type I Ha1(gene name synonym)|uniprotkb:Keratin-31(gene name synonym)|uniprotkb:KRT31(gene name)|psi-mi:KRT31(display_short)|uniprotkb:HHA1(gene name synonym)|uniprotkb:HKA1(gene name synonym)|uniprotkb:KRTHA1(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468761	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002268.2|ensembl:ENSG00000094796(gene)|ensembl:ENSG00000262993(gene)|ensembl:ENST00000251645(transcript)|ensembl:ENST00000573281(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3881(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16436615(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ur97LEvtqaqu3wh7iaX4HhN163k9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:VxPytE6UZRhjO0DKz44TlKx37og	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	uniprotkb:A0A0S2Z5U3	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	intact:EBI-16468000	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468745	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16436051(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:Zz9b0BZXfncU87N4Z4kLLYiPNYI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	uniprotkb:Q8WVV9	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468729	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16436051(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:7/a/HrIlQeAI38isVUxefihNbVc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:A0A0S2Z5U3	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-16468000	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468713	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16435758(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:Du5HIzuPqEj05euUqs/tA1pZIxc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08117-2	uniprotkb:A0A0S2Z5U3	intact:EBI-11741437|ensembl:ENSP00000221561	intact:EBI-16468000	psi-mi:q08117-2(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)|uniprotkb:AES-2(isoform synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468697	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104964(gene)|ensembl:ENST00000221561(transcript)|uniprotkb:Q08117-2(isoform-parent)|intact:EBI-717810(isoform-parent)|entrezgene/locuslink:166(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16435628(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Nrb311r8NRqcGyEJkPxvyjbpt6E9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:IJ6UpnDNCdRzcy9Yh1cP9h0BkpY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08117-2	uniprotkb:Q8WVV9	intact:EBI-11741437|ensembl:ENSP00000221561	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:q08117-2(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)|uniprotkb:AES-2(isoform synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468681	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104964(gene)|ensembl:ENST00000221561(transcript)|uniprotkb:Q08117-2(isoform-parent)|intact:EBI-717810(isoform-parent)|entrezgene/locuslink:166(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16435628(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Nrb311r8NRqcGyEJkPxvyjbpt6E9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:v24Xsp7Z75x5+AYMm7AMmWzc+GU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:A0A0S2Z5U3	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-16468000	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468665	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16435122(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:DAMlqINnTPTpv6NKqJxS98MnPS8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:Q8WVV9	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468649	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16435122(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:FyI9KSjpY7b+U+M4xOLwYRbJ2xA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978-2	uniprotkb:A0A0S2Z5U3	intact:EBI-7060731|ensembl:ENSP00000365439|ensembl:ENSP00000365458|uniprotkb:Q07244-2|intact:MINT-225449	intact:EBI-16468000	psi-mi:p61978-2(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468632	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|ensembl:ENST00000376263(transcript)|ensembl:ENST00000376281(transcript)|intact:EBI-304185(isoform-parent)|uniprotkb:P61978-2(isoform-parent)|entrezgene/locuslink:3190(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16434768(see-also)|intact:EBI-16434778(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FX/iS2YfOhD0ntY2oqpOUetACqg9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:rzNpHAo4KZdPN17UNQJT9LJaXRs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13838	uniprotkb:A0A0S2Z5U3	intact:EBI-348622|uniprotkb:B0S8C0|uniprotkb:Q5STB8|uniprotkb:O43496|uniprotkb:Q0EFA1|uniprotkb:Q2L6F9|uniprotkb:Q53GL9|uniprotkb:Q5RJ64|uniprotkb:Q5RJ66|uniprotkb:Q5ST94|uniprotkb:Q5STB4|uniprotkb:Q5STB5|uniprotkb:Q5STB7|uniprotkb:Q5STU4|uniprotkb:Q5STU5|uniprotkb:Q5STU6|uniprotkb:Q5STU8|uniprotkb:Q71V76|ensembl:ENSP00000373000|ensembl:ENSP00000379475|ensembl:ENSP00000383151|ensembl:ENSP00000383152|ensembl:ENSP00000387994|ensembl:ENSP00000388880|ensembl:ENSP00000390999|ensembl:ENSP00000391463|ensembl:ENSP00000393712|ensembl:ENSP00000394160|ensembl:ENSP00000398775|ensembl:ENSP00000399030|ensembl:ENSP00000400326|ensembl:ENSP00000404695|ensembl:ENSP00000405560|ensembl:ENSP00000407419|ensembl:ENSP00000411136|ensembl:ENSP00000411853|ensembl:ENSP00000416269	intact:EBI-16468000	psi-mi:dx39b_human(display_long)|uniprotkb:UAP56(gene name synonym)|uniprotkb:DDX39B(gene name)|psi-mi:DDX39B(display_short)|uniprotkb:DEAD box protein UAP56(gene name synonym)|uniprotkb:56 kDa U2AF65-associated protein(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p47(gene name synonym)|uniprotkb:HLA-B-associated transcript 1 protein(gene name synonym)|uniprotkb:BAT1(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468616	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004631.1|refseq:NP_542165.1|ensembl:ENSG00000198563(gene)|ensembl:ENSG00000215425(gene)|ensembl:ENSG00000225073(gene)|ensembl:ENSG00000225859(gene)|ensembl:ENSG00000229496(gene)|ensembl:ENSG00000230624(gene)|ensembl:ENSG00000235439(gene)|ensembl:ENST00000383508(transcript)|ensembl:ENST00000396172(transcript)|ensembl:ENST00000400295(transcript)|ensembl:ENST00000400296(transcript)|ensembl:ENST00000412106(transcript)|ensembl:ENST00000412330(transcript)|ensembl:ENST00000413678(transcript)|ensembl:ENST00000414440(transcript)|ensembl:ENST00000415689(transcript)|ensembl:ENST00000416863(transcript)|ensembl:ENST00000430784(transcript)|ensembl:ENST00000431360(transcript)|ensembl:ENST00000441425(transcript)|ensembl:ENST00000445218(transcript)|ensembl:ENST00000448296(transcript)|ensembl:ENST00000453138(transcript)|ensembl:ENST00000456476(transcript)|ensembl:ENST00000456666(transcript)|ensembl:ENST00000458640(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000346"(transcription export complex)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0008380"(RNA splicing)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q13838|rcsb pdb:1T5I|rcsb pdb:1T6N|rcsb pdb:1XTI|rcsb pdb:1XTJ|rcsb pdb:1XTK|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9013418|entrezgene/locuslink:7919(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16433809(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Cl/rf1oq31fZbLHC2foUXu9MBOE9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:Eh7uekCpI3ddTEjTraIG2XjUq70	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13838	uniprotkb:Q8WVV9	intact:EBI-348622|uniprotkb:B0S8C0|uniprotkb:Q5STB8|uniprotkb:O43496|uniprotkb:Q0EFA1|uniprotkb:Q2L6F9|uniprotkb:Q53GL9|uniprotkb:Q5RJ64|uniprotkb:Q5RJ66|uniprotkb:Q5ST94|uniprotkb:Q5STB4|uniprotkb:Q5STB5|uniprotkb:Q5STB7|uniprotkb:Q5STU4|uniprotkb:Q5STU5|uniprotkb:Q5STU6|uniprotkb:Q5STU8|uniprotkb:Q71V76|ensembl:ENSP00000373000|ensembl:ENSP00000379475|ensembl:ENSP00000383151|ensembl:ENSP00000383152|ensembl:ENSP00000387994|ensembl:ENSP00000388880|ensembl:ENSP00000390999|ensembl:ENSP00000391463|ensembl:ENSP00000393712|ensembl:ENSP00000394160|ensembl:ENSP00000398775|ensembl:ENSP00000399030|ensembl:ENSP00000400326|ensembl:ENSP00000404695|ensembl:ENSP00000405560|ensembl:ENSP00000407419|ensembl:ENSP00000411136|ensembl:ENSP00000411853|ensembl:ENSP00000416269	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:dx39b_human(display_long)|uniprotkb:UAP56(gene name synonym)|uniprotkb:DDX39B(gene name)|psi-mi:DDX39B(display_short)|uniprotkb:DEAD box protein UAP56(gene name synonym)|uniprotkb:56 kDa U2AF65-associated protein(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p47(gene name synonym)|uniprotkb:HLA-B-associated transcript 1 protein(gene name synonym)|uniprotkb:BAT1(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468600	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004631.1|refseq:NP_542165.1|ensembl:ENSG00000198563(gene)|ensembl:ENSG00000215425(gene)|ensembl:ENSG00000225073(gene)|ensembl:ENSG00000225859(gene)|ensembl:ENSG00000229496(gene)|ensembl:ENSG00000230624(gene)|ensembl:ENSG00000235439(gene)|ensembl:ENST00000383508(transcript)|ensembl:ENST00000396172(transcript)|ensembl:ENST00000400295(transcript)|ensembl:ENST00000400296(transcript)|ensembl:ENST00000412106(transcript)|ensembl:ENST00000412330(transcript)|ensembl:ENST00000413678(transcript)|ensembl:ENST00000414440(transcript)|ensembl:ENST00000415689(transcript)|ensembl:ENST00000416863(transcript)|ensembl:ENST00000430784(transcript)|ensembl:ENST00000431360(transcript)|ensembl:ENST00000441425(transcript)|ensembl:ENST00000445218(transcript)|ensembl:ENST00000448296(transcript)|ensembl:ENST00000453138(transcript)|ensembl:ENST00000456476(transcript)|ensembl:ENST00000456666(transcript)|ensembl:ENST00000458640(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000346"(transcription export complex)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0008380"(RNA splicing)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q13838|rcsb pdb:1T5I|rcsb pdb:1T6N|rcsb pdb:1XTI|rcsb pdb:1XTJ|rcsb pdb:1XTK|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9013418|entrezgene/locuslink:7919(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16433809(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Cl/rf1oq31fZbLHC2foUXu9MBOE9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:CwITTwo/IdQaJ4Es/pPKgp0TPR4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P98175-4	uniprotkb:A0A0S2Z5U3	intact:EBI-10968858|ensembl:ENSP00000486115	intact:EBI-16468000	psi-mi:p98175-4(display_long)|uniprotkb:RBM10(gene name)|psi-mi:RBM10(display_short)|uniprotkb:DXS8237E(gene name synonym)|uniprotkb:G patch domain-containing protein 9(gene name synonym)|uniprotkb:GPATC9(gene name synonym)|uniprotkb:GPATCH9(gene name synonym)|uniprotkb:KIAA0122(gene name synonym)|uniprotkb:RNA-binding motif protein 10(gene name synonym)|uniprotkb:RNA-binding protein S1-1(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468584	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-721525(isoform-parent)|ensembl:ENSG00000182872(gene)|ensembl:ENST00000628161(transcript)|entrezgene/locuslink:8241(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16433799(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:iKoFJ4bQhvGZ0Kq82Fhif11nCSA9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:4s+ryo4+MB7DAB5XOj8PUuYq/S4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:A0A0S2Z5U3	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-16468000	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468568	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16433739(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:D1ta9nzNlWZpiXef7F3K4tx/sPI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:Q8WVV9	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468552	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16433739(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:5wz5ShuFyIlTYmqnLli1FTU620E	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00148	uniprotkb:A0A0S2Z5U3	intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1	intact:EBI-16468000	psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468536	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1|entrezgene/locuslink:10212(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16433476(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:2+L52NBnsNKHr2x13xXMQG7FxTc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00148	uniprotkb:Q8WVV9	intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468520	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1|entrezgene/locuslink:10212(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16433476(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:/Tnt2ZSOxCm3YzJ0zXDMNo3fwDg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:A0A0S2Z5U3	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-16468000	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468504	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16433047(see-also)	crc64:609B121DA1A9DCB8	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:G/gRHs9KISrMjyqBqzMt7Lgck9Y	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:Q8WVV9	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468488	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16433047(see-also)	crc64:609B121DA1A9DCB8	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:WSVxO54hEznojoFpOz/bZpqWROg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5JST6	uniprotkb:A0A0S2Z5U3	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	intact:EBI-16468000	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468472	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16432726(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:APmJJU6MaltQc/yFXLl1jpZXxqo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:A0A0S2Z5U3	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-16468000	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468456	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16432416(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:S/hUnw+Q3wG1z3rA+Y+LJXvt/4M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:Q8WVV9	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468440	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16432416(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:a4F4s0coAqm1d19Kgl2R8/l+Zgo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:A0A0S2Z5U3	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16468000	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468424	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16432148(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:neNI/e6ct3YS3jVzT6XWIQyDcdA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q8WVV9	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468408	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16432148(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:IF2wLf8qhyWMxYoj7vQplA0BgTI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14503	uniprotkb:A0A0S2Z5U3	intact:EBI-711810|uniprotkb:Q96TD3|ensembl:ENSP00000256495	intact:EBI-16468000	psi-mi:bhe40_human(display_long)|uniprotkb:BHLHE40(gene name)|psi-mi:BHLHE40(display_short)|uniprotkb:Differentially expressed in chondrocytes protein 1(gene name synonym)|uniprotkb:Enhancer-of-split and hairy-related protein 2(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein(gene name synonym)|uniprotkb:BHLHB2(gene name synonym)|uniprotkb:DEC1(gene name synonym)|uniprotkb:SHARP2(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 2(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468392	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134107(gene)|ensembl:ENST00000256495(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_003661.1|dip:DIP-36698N|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:O14503|reactome:R-HSA-1368108|entrezgene/locuslink:8553(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16432088(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JZrZ1Yo2PF33s9Lf8rLTHCqoptk9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:OqvUyfmkBZOInwv6PQlz7miJtjc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14503	uniprotkb:Q8WVV9	intact:EBI-711810|uniprotkb:Q96TD3|ensembl:ENSP00000256495	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:bhe40_human(display_long)|uniprotkb:BHLHE40(gene name)|psi-mi:BHLHE40(display_short)|uniprotkb:Differentially expressed in chondrocytes protein 1(gene name synonym)|uniprotkb:Enhancer-of-split and hairy-related protein 2(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein(gene name synonym)|uniprotkb:BHLHB2(gene name synonym)|uniprotkb:DEC1(gene name synonym)|uniprotkb:SHARP2(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 2(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468376	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134107(gene)|ensembl:ENST00000256495(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_003661.1|dip:DIP-36698N|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:O14503|reactome:R-HSA-1368108|entrezgene/locuslink:8553(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16432088(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JZrZ1Yo2PF33s9Lf8rLTHCqoptk9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:ntBrV/xXX1Bc4+KirPCiXFhoFv8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:A0A0S2Z5U3	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-16468000	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468360	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16430783(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:lFaed2VIrUq3XZEeOXscngJ9kc4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:Q8WVV9	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468344	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16430783(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:++rZAaxmSSyoR4mTJpF4UAhalF0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99836	uniprotkb:F8VVZ1	intact:EBI-447677|uniprotkb:P78397|uniprotkb:Q53XS7|uniprotkb:B4DKH8|uniprotkb:B4DKU4|uniprotkb:J3KPU4|uniprotkb:J3KQ87|uniprotkb:J3KQJ6|uniprotkb:B4DQ60|uniprotkb:B4DQ72|ensembl:ENSP00000379625|ensembl:ENSP00000498360	intact:EBI-16469141|ensembl:ENSP00000448197|ensembl:ENSP00000449553|ensembl:ENSP00000449693|ensembl:ENSP00000449859	psi-mi:myd88_human(display_long)|uniprotkb:MYD88(gene name)|psi-mi:MYD88(display_short)	psi-mi:f8vvz1_human(display_long)|uniprotkb:IRAK4(gene name)|psi-mi:IRAK4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469144	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166037.1|refseq:NP_001166039.1|refseq:NP_001166040.1|refseq:NP_002459.2|dip:DIP-31349N|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032747"(positive regulation of interleukin-23 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034158"(toll-like receptor 8 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0050671"(positive regulation of lymphocyte proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:2000338"("regulation of chemokine (C-X-C motif) ligand 1 production")|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR017281(Myeloid differentiation primary response protein MyD88)|interpro:IPR034249|interpro:IPR035897|mint:Q99836|rcsb pdb:2JS7|rcsb pdb:2Z5V|rcsb pdb:3MOP|rcsb pdb:4DOM|rcsb pdb:4EO7|rcsb pdb:6I3N|rcsb pdb:7BEQ|rcsb pdb:7BER|rcsb pdb:7L6W|reactome:R-HSA-1236974|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-1810476|reactome:R-HSA-209543|reactome:R-HSA-3134963|reactome:R-HSA-5602498|reactome:R-HSA-5602680|reactome:R-HSA-5603037|reactome:R-HSA-5603041|reactome:R-HSA-6811558|reactome:R-HSA-9020702|reactome:R-HSA-975110|reactome:R-HSA-975155|reactome:R-HSA-975871|reactome:R-HSA-975138|ensembl:ENSG00000172936(gene)|ensembl:ENST00000396334(transcript)|ensembl:ENST00000650905(transcript)|go:"GO:0002238"(response to molecule of fungal origin)|go:"GO:0002269"(leukocyte activation involved in inflammatory response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005121"(Toll binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007254"(JNK cascade)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009682"(induced systemic resistance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0070944"(neutrophil-mediated killing of bacterium)|go:"GO:0070976"(TIR domain binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:0050830"(defense response to Gram-positive bacterium)|entrezgene/locuslink:4615(identity)	ensembl:ENSG00000198001(gene)|ensembl:ENST00000547521(transcript)|ensembl:ENST00000550361(transcript)|ensembl:ENST00000550615(transcript)|ensembl:ENST00000552309(transcript)|go:"GO:0016301"(kinase activity)|interpro:IPR011029(DEATH-like)|entrezgene/locuslink:51135(identity)	intact:EBI-16431429(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:B920s5F0eUql/jtwlByyhI7ojGI9606	rogid:tyQt66S4ehIfxE18YIVr6Ylmlak9606	rigid:QVILkOlqjXtQIStSYBQ+ZabZyKI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:P49441	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-725432|ensembl:ENSP00000325423|ensembl:ENSP00000376142	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:inpp_human(display_long)|uniprotkb:INPP1(gene name)|psi-mi:INPP1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469125	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	refseq:NP_001122400.1|refseq:NP_002185.1|refseq:XP_005246589.1|ensembl:ENSG00000151689(gene)|ensembl:ENST00000322522(transcript)|ensembl:ENST00000392329(transcript)|go:"GO:0004441"(inositol-1,4-bisphosphate 1-phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020583|reactome:R-HSA-1855183|entrezgene/locuslink:3628(identity)	intact:EBI-16433613(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:nPr4mBqj4mWyNAWpbA+BY1Z8ZU49606	rigid:PK/xydskR5ISgDMbQ79JdY7CkF4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P20393	uniprotkb:P49441	intact:EBI-2811738|uniprotkb:Q15304|uniprotkb:Q0P5Z4|ensembl:ENSP00000246672	intact:EBI-725432|ensembl:ENSP00000325423|ensembl:ENSP00000376142	psi-mi:nr1d1_human(display_long)|uniprotkb:NR1D1(gene name)|psi-mi:NR1D1(display_short)|uniprotkb:EAR1(gene name synonym)|uniprotkb:HREV(gene name synonym)|uniprotkb:THRAL(gene name synonym)|uniprotkb:Rev-erbA-alpha(gene name synonym)|uniprotkb:V-erbA-related protein 1(gene name synonym)	psi-mi:inpp_human(display_long)|uniprotkb:INPP1(gene name)|psi-mi:INPP1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469109	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068370.1|ensembl:ENSG00000126368(gene)|ensembl:ENST00000246672(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031648"(protein destabilization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043197"(dendritic spine)|go:"GO:0044321"(response to leptin)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0061889"(negative regulation of astrocyte activation)|go:"GO:0070859"(positive regulation of bile acid biosynthetic process)|go:"GO:0070888"(E-box binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0150079"(negative regulation of neuroinflammatory response)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1A6Y|rcsb pdb:1EF6|rcsb pdb:1GA5|rcsb pdb:1HLZ|rcsb pdb:3N00|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-9707616|dip:DIP-48396N|entrezgene/locuslink:9572(identity)	refseq:NP_001122400.1|refseq:NP_002185.1|refseq:XP_005246589.1|ensembl:ENSG00000151689(gene)|ensembl:ENST00000322522(transcript)|ensembl:ENST00000392329(transcript)|go:"GO:0004441"(inositol-1,4-bisphosphate 1-phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020583|reactome:R-HSA-1855183|entrezgene/locuslink:3628(identity)	intact:EBI-16430608(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UfaVQzUQ3wD4xDBh1sjp+eaawY89606	rogid:nPr4mBqj4mWyNAWpbA+BY1Z8ZU49606	rigid:PwAXSbfGyz/hAEX1ymmifS0Eoi4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NHQ1	intact:EBI-16469090	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	-	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"ccsb isoform id: hspd1_4"(display_short)|psi-mi:EBI-16469090(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469093	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	entrezgene/locuslink:3329(identity)	intact:EBI-16432228(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:hhB7/gWvIqi2AaZO0SBi2IWXwio9606	rigid:yVscnBLaZq/kivevgQZnGrCS7cA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NHQ1	intact:EBI-16469071	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	-	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"ccsb isoform id: hspd1_2"(display_short)|psi-mi:EBI-16469071(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469074	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	entrezgene/locuslink:3329(identity)	intact:EBI-16432228(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:h9GgE/V//AvJcuqOedYq2wr49Pc9606	rigid:PDmrtgoijYIWQUUgKcL81vsKSkI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y5V3	uniprotkb:A0A0S2Z5U3	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927	intact:EBI-16468000	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469055	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889|entrezgene/locuslink:9500(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16440594(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:9bGQVleeOW5VRiK3ossnN2APJOA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y5V3	uniprotkb:Q8WVV9	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469039	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889|entrezgene/locuslink:9500(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16440594(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:ZaCwLYCOfLnWFpeH5K7YtKGVOUk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6UY14-3	uniprotkb:A0A0S2Z5U3	intact:EBI-10173507|ensembl:ENSP00000358035|ensembl:ENSP00000501295	intact:EBI-16468000	psi-mi:q6uy14-3(display_long)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469020	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143382(gene)|ensembl:ENST00000369039(transcript)|ensembl:ENST00000674043(transcript)|intact:EBI-742002(isoform-parent)|uniprotkb:Q6UY14-3(isoform-parent)|entrezgene/locuslink:54507(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16440344(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7EB8HdDfZI57O38GQO8ZSygWp2U9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:VoSVGaG0uHvirP/euLfEGmKDnEw	true	sufficient binding region:674-1097	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6UY14-3	uniprotkb:Q8WVV9	intact:EBI-10173507|ensembl:ENSP00000358035|ensembl:ENSP00000501295	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:q6uy14-3(display_long)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469001	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143382(gene)|ensembl:ENST00000369039(transcript)|ensembl:ENST00000674043(transcript)|intact:EBI-742002(isoform-parent)|uniprotkb:Q6UY14-3(isoform-parent)|entrezgene/locuslink:54507(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16440344(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7EB8HdDfZI57O38GQO8ZSygWp2U9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:mgjhHNmKKZzqo5oFO3dErjNy2Qo	true	sufficient binding region:674-1097	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43597	uniprotkb:A0A0S2Z5U3	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	intact:EBI-16468000	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468985	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16438980(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u1omauzisc6MdZlogMotUmtauSI9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:98Rdl7v1gaeTCJVn87bSctg+iPY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43597	uniprotkb:Q8WVV9	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468969	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16438980(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u1omauzisc6MdZlogMotUmtauSI9606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:yU67t0qGg1IRr2FK8STnjK7hywo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978	uniprotkb:A0A0S2Z5U3	intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1	intact:EBI-16468000	psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468953	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N|entrezgene/locuslink:3190(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16438850(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:JvtnlIBDfrD6srCGlwddnIzucVg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478	uniprotkb:A0A0S2Z5U3	intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016	intact:EBI-16468000	psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)	psi-mi:a0a0s2z5u3_human(display_long)|uniprotkb:HNRPLL(gene name)|psi-mi:HNRPLL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468937	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR034985|interpro:IPR034986|interpro:IPR034983|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|interpro:IPR021790|entrezgene/locuslink:92906(identity)	intact:EBI-16438071(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606	rogid:YOsGERoLdlCVJVfYaFThi//U3/k9606	rigid:AwTNFyfZ8etJs2GyihwDcISIKvo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478	uniprotkb:Q8WVV9	intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625	psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16468921	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity)	refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene)|entrezgene/locuslink:92906(identity)	intact:EBI-16438071(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rigid:L7p3ap1/F9hRe1kTAvUqEto5vF8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	uniprotkb:P26440-2	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	intact:EBI-16469190|ensembl:ENSP00000498731	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:p26440-2(display_long)|uniprotkb:Butyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:IVD(gene name)|psi-mi:IVD(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469196	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	intact:EBI-2866408(isoform-parent)|ensembl:ENSG00000128928(gene)|ensembl:ENST00000650656(transcript)|entrezgene/locuslink:3712(identity)	intact:EBI-16429173(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2018/09/18	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:QjW2mNCenQf/Ih5vqq4aG6P1xUU9606	rigid:xupT8yO5GweGyqhVckdBNSqbcJ0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	uniprotkb:P26440	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	intact:EBI-2866408|uniprotkb:J3KR54|uniprotkb:Q53XZ9|uniprotkb:Q96AF6|uniprotkb:B2RCV5|uniprotkb:B3KVI7|ensembl:ENSP00000499074	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:ivd_human(display_long)|uniprotkb:IVD(gene name)|psi-mi:IVD(display_short)|uniprotkb:Butyryl-CoA dehydrogenase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469174	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	refseq:NP_002216.2|refseq:NP_001152980.1|ensembl:ENSG00000128928(gene)|ensembl:ENST00000651168(transcript)|go:"GO:0004085"(butyryl-CoA dehydrogenase activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0008470"(isovaleryl-CoA dehydrogenase activity)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042802"(identical protein binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034183|interpro:IPR036250|interpro:IPR037069|rcsb pdb:1IVH|reactome:R-HSA-70895|entrezgene/locuslink:3712(identity)	intact:EBI-16429173(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2018/09/18	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:GewB1Yyc2EEVepN5e1H068xpjI09606	rigid:V01dUY2LBYA0pDOhCiibH8UgbGg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:A0A0S2Z5P4	intact:EBI-16439278	intact:EBI-16469235	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:a0a0s2z5p4_human(display_long)|uniprotkb:JMJD5(gene name)|psi-mi:JMJD5(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469241	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	interpro:IPR041667|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|entrezgene/locuslink:79831(identity)	intact:EBI-16439577(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:7/IA0JDDT45tTJ9vbsjpiFn5GSk9606	rigid:y04mg9Om7j70bktrA8ZPaoBSIek	true	-	sufficient binding region:1-300	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UHX1-6	uniprotkb:A0A0S2Z5A4	intact:EBI-11085298|ensembl:ENSP00000431960	intact:EBI-16469260	psi-mi:q9uhx1-6(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:a0a0s2z5a4_human(display_long)|uniprotkb:KIAA0907(gene name)|psi-mi:KIAA0907(display_short)|uniprotkb:KH homology domain-containing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469263	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000179950(gene)|ensembl:ENST00000527197(transcript)|intact:EBI-1053259(isoform-parent)|uniprotkb:Q9UHX1-6(isoform-parent)|entrezgene/locuslink:22827(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036612|interpro:IPR031121|entrezgene/locuslink:22889(identity)	intact:EBI-16433440(see-also)	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:rSsTImwmpEAWMCxLzF5Y4zVdeFM9606	rogid:DV9J710SOPNGaqeNv+Gpuyh0Mus9606	rigid:cTkVOaaYUWoS6dUgmNxlyeEDSbo	true	sufficient binding region:15-513	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q14498-3	uniprotkb:A0A0S2Z5A4	intact:EBI-6654703|ensembl:ENSP00000436747	intact:EBI-16469260	psi-mi:q14498-3(display_long)|uniprotkb:RBM39(gene name)|psi-mi:RBM39(display_short)|uniprotkb:HCC1(gene name synonym)|uniprotkb:RNPC2(gene name synonym)|uniprotkb:Hepatocellular carcinoma protein 1(gene name synonym)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Splicing factor HCC1(gene name synonym)|uniprotkb:CAPER alpha(gene name synonym)	psi-mi:a0a0s2z5a4_human(display_long)|uniprotkb:KIAA0907(gene name)|psi-mi:KIAA0907(display_short)|uniprotkb:KH homology domain-containing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469282	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131051(gene)|ensembl:ENST00000528062(transcript)|intact:EBI-395290(isoform-parent)|entrezgene/locuslink:9584(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036612|interpro:IPR031121|entrezgene/locuslink:22889(identity)	intact:EBI-16435466(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:gEOR16XItpn4AN2H+cvwNQW+IUU9606	rogid:DV9J710SOPNGaqeNv+Gpuyh0Mus9606	rigid:E2rejSS7nrL/+ovvfT8hwE5zmFY	true	sufficient binding region:136-508	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UHX1-2	uniprotkb:A0A0S2Z5A4	intact:EBI-11529177|ensembl:ENSP00000322036|ensembl:ENSP00000478495	intact:EBI-16469260	psi-mi:q9uhx1-2(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:a0a0s2z5a4_human(display_long)|uniprotkb:KIAA0907(gene name)|psi-mi:KIAA0907(display_short)|uniprotkb:KH homology domain-containing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469301	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000349157(transcript)|ensembl:ENST00000612237(transcript)|uniprotkb:Q9UHX1-2(isoform-parent)|entrezgene/locuslink:22827(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036612|interpro:IPR031121|entrezgene/locuslink:22889(identity)	intact:EBI-16435982(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:snVN9Lw5+MP2/aiq4z08ANwvr209606	rogid:DV9J710SOPNGaqeNv+Gpuyh0Mus9606	rigid:Hw+S3XiHqNDuxVzCFZ5lL9SGZ/8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UHX1-5	uniprotkb:A0A0S2Z5A4	intact:EBI-11526420|ensembl:ENSP00000395417|ensembl:ENSP00000478209	intact:EBI-16469260	psi-mi:q9uhx1-5(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:a0a0s2z5a4_human(display_long)|uniprotkb:KIAA0907(gene name)|psi-mi:KIAA0907(display_short)|uniprotkb:KH homology domain-containing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469317	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000456095(transcript)|ensembl:ENST00000620953(transcript)|entrezgene/locuslink:22827(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036612|interpro:IPR031121|entrezgene/locuslink:22889(identity)	intact:EBI-16437536(see-also)	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PSbIU++DIL6ysF0ccd3ZHzeJ5rs9606	rogid:DV9J710SOPNGaqeNv+Gpuyh0Mus9606	rigid:9B5t8xjS+JgND1CChJZSmm6eLD0	true	sufficient binding region:15-530	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:A0A0S2Z5A4	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-16469260	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:a0a0s2z5a4_human(display_long)|uniprotkb:KIAA0907(gene name)|psi-mi:KIAA0907(display_short)|uniprotkb:KH homology domain-containing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469336	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036612|interpro:IPR031121|entrezgene/locuslink:22889(identity)	intact:EBI-16440322(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:DV9J710SOPNGaqeNv+Gpuyh0Mus9606	rigid:sWd4ZZwUdD0Cc53eKgU0JtB/aXU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O14964	intact:EBI-16431876	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	-	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"ccsb isoform id: krt6a_2"(display_short)|psi-mi:EBI-16431876(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469352	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	entrezgene/locuslink:3853(identity)	intact:EBI-16433891(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:yW9Icx0fchBmUxpcpz1lpDgBoy09606	rigid:VnT0TSCNeiYE5oreHYVbSzkXmj4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P02538	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-702198|uniprotkb:P48667|uniprotkb:Q08AR4|uniprotkb:Q6NT67|uniprotkb:Q96CL4|uniprotkb:A4QPC1|ensembl:ENSP00000369317	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:k2c6a_human(display_long)|uniprotkb:Cytokeratin-6A(gene name synonym)|uniprotkb:Keratin-6A(gene name synonym)|uniprotkb:Cytokeratin-6D(gene name synonym)|uniprotkb:KRT6A(gene name)|psi-mi:KRT6A(display_short)|uniprotkb:K6A(gene name synonym)|uniprotkb:KRT6D(gene name synonym)|uniprotkb:Type-II keratin Kb6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469368	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	refseq:NP_005545.1|dip:DIP-533N|ensembl:ENSG00000205420(gene)|ensembl:ENST00000330722(transcript)|go:"GO:0001899"(negative regulation of cytolysis by symbiont of host cells)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0042060"(wound healing)|go:"GO:0045095"(keratin filament)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000536"(negative regulation of entry of bacterium into host cell)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P02538|rcsb pdb:5KI0|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3853(identity)	intact:EBI-16440858(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:feIxUFTSMnjattUda5vdGhiL9H89606	rigid:fBRLkKK7sK9U7JyNb2HH6XM9jms	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:Q13751	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-2529833|uniprotkb:O14947|uniprotkb:Q14733|uniprotkb:Q9UJK4|uniprotkb:Q9UJL1|uniprotkb:D3DT88|ensembl:ENSP00000348384|ensembl:ENSP00000355997|ensembl:ENSP00000375778	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:lamb3_human(display_long)|uniprotkb:Epiligrin subunit bata(gene name synonym)|uniprotkb:Kalinin subunit beta(gene name synonym)|uniprotkb:Nicein subunit beta(gene name synonym)|uniprotkb:LAMB3(gene name)|psi-mi:LAMB3(display_short)|uniprotkb:LAMNB1(gene name synonym)|uniprotkb:Laminin-5 subunit beta(gene name synonym)|uniprotkb:Laminin B1k chain(gene name synonym)|uniprotkb:Kalinin B1 chain(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469384	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	ensembl:ENSG00000196878(gene)|ensembl:ENST00000356082(transcript)|ensembl:ENST00000367030(transcript)|ensembl:ENST00000391911(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005610"(laminin-5 complex)|go:"GO:0008544"(epidermis development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043256"(laminin complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|mint:Q13751|reactome:R-HSA-1474228|reactome:R-HSA-2022090|reactome:R-HSA-2214320|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-446107|reactome:R-HSA-8874081|refseq:NP_000219.2|refseq:NP_001017402.1|refseq:NP_001121113.1|refseq:XP_005273181.1|entrezgene/locuslink:3914(identity)	intact:EBI-16435134(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:sZg1IU7enqhMRqryIrBkYRSP8/k9606	rigid:zxam11yPBqnBQzywp8c8fPR4qCE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:I6L996	uniprotkb:A0A0S2Z3Y4	intact:EBI-10181089	intact:EBI-16469400	psi-mi:i6l996_human(display_long)|uniprotkb:PTK2(gene name)|psi-mi:PTK2(display_short)	psi-mi:a0a0s2z3y4_human(display_long)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469416	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036137|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR005189(Focal adhesion targeting region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0007172"(signal complex assembly)|entrezgene/locuslink:5747(identity)	go:"GO:0005886"(plasma membrane)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|refseq:NP_001317397.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR035850|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:3932(identity)	intact:EBI-16432436(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aHSFMTSzdwboAzFgymTQXp0AiP49606	rogid://TSM44HoapvCeNP+Vtuoiu+PlM9606	rigid:oV/7ntFsyUZVpM9MmJUPQn3SWNY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P23771	uniprotkb:P06239-3	intact:EBI-6664760|ensembl:ENSP00000341619|uniprotkb:Q5VWG7|uniprotkb:Q5VWG8|uniprotkb:Q96J16	intact:EBI-13287659|ensembl:ENSP00000328213	psi-mi:gata3_human(display_long)|uniprotkb:GATA3(gene name)|psi-mi:GATA3(display_short)|uniprotkb:GATA-binding factor 3(gene name synonym)	psi-mi:p06239-3(display_long)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:Protein YT16(gene name synonym)|uniprotkb:Proto-oncogene Lck(gene name synonym)|uniprotkb:T cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469432	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107485(gene)|ensembl:ENST00000346208(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001764"(neuron migration)|go:"GO:0001806"(type IV hypersensitivity)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002520"(immune system development)|go:"GO:0002572"(pro-T cell differentiation)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006959"(humoral immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009615"(response to virus)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030856"(regulation of epithelial cell differentiation)|go:"GO:0031929"(TOR signaling)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035799"(ureter maturation)|go:"GO:0035898"(parathyroid hormone secretion)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043583"(ear development)|go:"GO:0043627"(response to estrogen)|go:"GO:0045061"(thymic T cell selection)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045471"(response to ethanol)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0072178"(nephric duct morphogenesis)|go:"GO:0072179"(nephric duct formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072676"(lymphocyte migration)|go:"GO:0090102"(cochlea development)|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|go:"GO:2000607"(negative regulation of cell proliferation involved in mesonephros development)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0072107"(positive regulation of ureteric bud formation)|go:"GO:2000703"(negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation)|go:"GO:2000734"(negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029521|interpro:IPR039355|rcsb pdb:4HC7|rcsb pdb:4HC9|rcsb pdb:4HCA|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-983231|go:"GO:2000683"(regulation of cellular response to X-ray)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060374"(mast cell differentiation)|go:"GO:0060676"(ureteric bud formation)|go:"GO:0061085"(regulation of histone H3-K27 methylation)|go:"GO:0061290"(canonical Wnt signaling pathway involved in metanephric kidney development)|go:"GO:0070888"(E-box binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071442"(positive regulation of histone H3-K14 acetylation)|go:"GO:0071599"(otic vesicle development)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0048589"(developmental growth)|refseq:XP_005252499.1|refseq:XP_005252500.1|refseq:NP_001002295.1|refseq:NP_002042.1|dip:DIP-61302N|entrezgene/locuslink:2625(identity)	uniprotkb:P06239-3(isoform-parent)|intact:EBI-1348(isoform-parent)|ensembl:ENSG00000182866(gene)|ensembl:ENST00000333070(transcript)|entrezgene/locuslink:3932(identity)	intact:EBI-16433643(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CHTPVKH4qSR/pDIf/vMr+kChpzc9606	rogid:AhIzJ3C93NIaoYcShniBSfH0sAI9606	rigid:8dMore1eiVDxzMNBHygQh/w34dQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P23771	uniprotkb:A0A0S2Z3Y4	intact:EBI-6664760|ensembl:ENSP00000341619|uniprotkb:Q5VWG7|uniprotkb:Q5VWG8|uniprotkb:Q96J16	intact:EBI-16469400	psi-mi:gata3_human(display_long)|uniprotkb:GATA3(gene name)|psi-mi:GATA3(display_short)|uniprotkb:GATA-binding factor 3(gene name synonym)	psi-mi:a0a0s2z3y4_human(display_long)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469448	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107485(gene)|ensembl:ENST00000346208(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001764"(neuron migration)|go:"GO:0001806"(type IV hypersensitivity)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002520"(immune system development)|go:"GO:0002572"(pro-T cell differentiation)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006959"(humoral immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009615"(response to virus)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030856"(regulation of epithelial cell differentiation)|go:"GO:0031929"(TOR signaling)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035799"(ureter maturation)|go:"GO:0035898"(parathyroid hormone secretion)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043583"(ear development)|go:"GO:0043627"(response to estrogen)|go:"GO:0045061"(thymic T cell selection)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045471"(response to ethanol)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0072178"(nephric duct morphogenesis)|go:"GO:0072179"(nephric duct formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072676"(lymphocyte migration)|go:"GO:0090102"(cochlea development)|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|go:"GO:2000607"(negative regulation of cell proliferation involved in mesonephros development)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0072107"(positive regulation of ureteric bud formation)|go:"GO:2000703"(negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation)|go:"GO:2000734"(negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029521|interpro:IPR039355|rcsb pdb:4HC7|rcsb pdb:4HC9|rcsb pdb:4HCA|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-983231|go:"GO:2000683"(regulation of cellular response to X-ray)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060374"(mast cell differentiation)|go:"GO:0060676"(ureteric bud formation)|go:"GO:0061085"(regulation of histone H3-K27 methylation)|go:"GO:0061290"(canonical Wnt signaling pathway involved in metanephric kidney development)|go:"GO:0070888"(E-box binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071442"(positive regulation of histone H3-K14 acetylation)|go:"GO:0071599"(otic vesicle development)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0048589"(developmental growth)|refseq:XP_005252499.1|refseq:XP_005252500.1|refseq:NP_001002295.1|refseq:NP_002042.1|dip:DIP-61302N|entrezgene/locuslink:2625(identity)	go:"GO:0005886"(plasma membrane)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|refseq:NP_001317397.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR035850|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:3932(identity)	intact:EBI-16433643(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CHTPVKH4qSR/pDIf/vMr+kChpzc9606	rogid://TSM44HoapvCeNP+Vtuoiu+PlM9606	rigid:mdFYt9kBXJiP1j9KmFxt0RSnGuU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:O75112-5	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-16469464|ensembl:ENSP00000485389	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:o75112-5(display_long)|uniprotkb:Protein cypher(gene name synonym)|uniprotkb:Z-band alternatively spliced PDZ-motif protein(gene name synonym)|uniprotkb:LDB3(gene name)|psi-mi:LDB3(display_short)|uniprotkb:KIAA0613(gene name synonym)|uniprotkb:ZASP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469472	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	intact:EBI-1222667(isoform-parent)|ensembl:ENSG00000122367(gene)|ensembl:ENST00000623007(transcript)|entrezgene/locuslink:11155(identity)	intact:EBI-16434013(see-also)	-	isoform-comment:"Variant in position: 315:R->C (in MFM-ZASP)."	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:27Yip0E8r+OuTAennn+6T2meYQE9606	rigid:vPaTJzDvRdvTrV/QkUu24/aBfaM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6UX01	uniprotkb:P43364	intact:EBI-8640839|ensembl:ENSP00000267102|uniprotkb:Q9NT09|intact:MINT-8163155|uniprotkb:Q969J4|uniprotkb:Q9NVE1|uniprotkb:Q9ULP6|uniprotkb:Q9NVU9|uniprotkb:Q96HN8|uniprotkb:Q96BY8	intact:EBI-739552|uniprotkb:Q5ETU4|uniprotkb:Q6ZRZ5|ensembl:ENSP00000347358	psi-mi:lmbrl_human(display_long)|uniprotkb:LMBR1L(gene name)|psi-mi:LMBR1L(display_short)|uniprotkb:KIAA1174(gene name synonym)|uniprotkb:LIMR(gene name synonym)|uniprotkb:Limb region 1 protein homolog-like(gene name synonym)|uniprotkb:Lipocalin-1-interacting membrane receptor(gene name synonym)|uniprotkb:UNQ458/PRO783(orf name)	psi-mi:magab_human(display_long)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)|uniprotkb:MAGE11(gene name synonym)|uniprotkb:MAGE-11 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.11(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469488	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139636(gene)|ensembl:ENST00000267102(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030217"(T cell differentiation)|go:"GO:0042098"(T cell proliferation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR006876(LMBR1-like conserved region)|interpro:IPR008075(Lipocalin-1 receptor)|refseq:NP_001287679.1|refseq:NP_001287680.1|refseq:NP_060583.2|entrezgene/locuslink:55716(identity)	refseq:NP_001011544.1|refseq:NP_005357.2|ensembl:ENSG00000185247(gene)|ensembl:ENST00000355220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43364|rcsb pdb:6WJH|refseq:XP_016885010.1|refseq:XP_016885011.1|entrezgene/locuslink:4110(identity)	intact:EBI-16434479(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:hPTmAiiZhDiXNLvPvM9io+B6Kqs9606	rogid:S0eOQssWhZCbAvWQCub2H+zQmzs9606	rigid:3PCjy4HhhiMVBtQMJFlGP8nC94E	true	-	sufficient binding region:111-429	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P43364	uniprotkb:A0A0S2Z5M5	intact:EBI-739552|uniprotkb:Q5ETU4|uniprotkb:Q6ZRZ5|ensembl:ENSP00000347358	intact:EBI-16469507	psi-mi:magab_human(display_long)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)|uniprotkb:MAGE11(gene name synonym)|uniprotkb:MAGE-11 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.11(gene name synonym)	psi-mi:a0a0s2z5m5_human(display_long)|uniprotkb:LMBR1L(gene name)|psi-mi:LMBR1L(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469510	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|refseq:NP_005357.2|ensembl:ENSG00000185247(gene)|ensembl:ENST00000355220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43364|rcsb pdb:6WJH|refseq:XP_016885010.1|refseq:XP_016885011.1|entrezgene/locuslink:4110(identity)	go:"GO:0016021"(integral component of membrane)|interpro:IPR008075(Lipocalin-1 receptor)|entrezgene/locuslink:55716(identity)	intact:EBI-16434479(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S0eOQssWhZCbAvWQCub2H+zQmzs9606	rogid:VN/wMhanEGUoiY78scdDRr5a2Ys9606	rigid:36lT4Sak9mM0vbjcqzC+KRMoeYM	true	sufficient binding region:111-429	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P43364	uniprotkb:Q6UX01-3	intact:EBI-739552|uniprotkb:Q5ETU4|uniprotkb:Q6ZRZ5|ensembl:ENSP00000347358	intact:EBI-16469529|ensembl:ENSP00000447329	psi-mi:magab_human(display_long)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)|uniprotkb:MAGE11(gene name synonym)|uniprotkb:MAGE-11 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.11(gene name synonym)	psi-mi:q6ux01-3(display_long)|uniprotkb:Limb region 1 protein homolog-like(gene name synonym)|uniprotkb:Lipocalin-1-interacting membrane receptor(gene name synonym)|uniprotkb:UNQ458/PRO783(orf name)|uniprotkb:LMBR1L(gene name)|psi-mi:LMBR1L(display_short)|uniprotkb:KIAA1174(gene name synonym)|uniprotkb:LIMR(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469538	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|refseq:NP_005357.2|ensembl:ENSG00000185247(gene)|ensembl:ENST00000355220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43364|rcsb pdb:6WJH|refseq:XP_016885010.1|refseq:XP_016885011.1|entrezgene/locuslink:4110(identity)	ensembl:ENSG00000139636(gene)|ensembl:ENST00000547382(transcript)|intact:EBI-8640839(isoform-parent)|entrezgene/locuslink:55716(identity)	intact:EBI-16434479(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S0eOQssWhZCbAvWQCub2H+zQmzs9606	rogid:j+AtYdU3X6My8X28WV4PPrTgIXw9606	rigid:TxbwyjO2qdNc46eiRUBGaNqWL60	true	sufficient binding region:111-429	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P43364	intact:EBI-16469557	intact:EBI-739552|uniprotkb:Q5ETU4|uniprotkb:Q6ZRZ5|ensembl:ENSP00000347358	-	psi-mi:magab_human(display_long)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)|uniprotkb:MAGE11(gene name synonym)|uniprotkb:MAGE-11 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.11(gene name synonym)	psi-mi:"ccsb isoform id: lmbr1l_5"(display_short)|psi-mi:EBI-16469557(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469560	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|refseq:NP_005357.2|ensembl:ENSG00000185247(gene)|ensembl:ENST00000355220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43364|rcsb pdb:6WJH|refseq:XP_016885010.1|refseq:XP_016885011.1|entrezgene/locuslink:4110(identity)	entrezgene/locuslink:55716(identity)	intact:EBI-16434479(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S0eOQssWhZCbAvWQCub2H+zQmzs9606	rogid:zpgJSFTm9M5ifWUxZG6m5y5PJSc9606	rigid:MqUNjQLoc3UCaM8ajRag+KkciFM	true	sufficient binding region:111-429	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:O15116	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469579	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body)|entrezgene/locuslink:27257(identity)	intact:EBI-16434025(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606	rigid:ylmuTENcglrvN8kvbbsELy/J0tc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:A0A0S2Z5P8	intact:EBI-16439278	intact:EBI-16469212	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:a0a0s2z5p8_human(display_long)|uniprotkb:JMJD5(gene name)|psi-mi:JMJD5(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469219	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	interpro:IPR041667|refseq:XP_016879165.1|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|entrezgene/locuslink:79831(identity)	intact:EBI-16439577(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:wBYujY+67BXE12wI+WLXxpSjeFU9606	rigid:prrEDH9RNJuC1bV1rgsFvceYnA0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NRG1	intact:EBI-16469675	intact:EBI-739759|uniprotkb:Q53HA7|uniprotkb:Q59EL9|uniprotkb:Q5VV18|uniprotkb:Q5VV20|uniprotkb:B7Z1Z3|ensembl:ENSP00000318602	-	psi-mi:prdc1_human(display_long)|uniprotkb:PRTFDC1(gene name)|psi-mi:PRTFDC1(display_short)|uniprotkb:HHGP(gene name synonym)	psi-mi:"ccsb isoform id: mcmbp_3"(display_short)|psi-mi:EBI-16469675(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469694	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269715.1|refseq:NP_064585.1|ensembl:ENSG00000099256(gene)|ensembl:ENST00000320152(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|rcsb pdb:2JBH|entrezgene/locuslink:56952(identity)	entrezgene/locuslink:79892(identity)	intact:EBI-16433217(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:grTZnSalFILRSeeZBjM1mTtF0xo9606	rogid:jlwzNIgLbSOvwlOEzQbiAfIAaM89606	rigid:47oIqZDLyHmWxpqlk0PzyxDGFKQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P04424	intact:EBI-16469675	intact:EBI-750131|uniprotkb:Q6LDS5|uniprotkb:Q96HS2|uniprotkb:E7EMI0|uniprotkb:E9PE48|ensembl:ENSP00000307188|ensembl:ENSP00000378741	-	psi-mi:arly_human(display_long)|uniprotkb:Arginosuccinase(gene name synonym)|uniprotkb:ASL(gene name)|psi-mi:ASL(display_short)	psi-mi:"ccsb isoform id: mcmbp_3"(display_short)|psi-mi:EBI-16469675(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469678	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000039.2|refseq:NP_001020114.1|refseq:NP_001020115.1|ensembl:ENSG00000126522(gene)|ensembl:ENST00000304874(transcript)|ensembl:ENST00000395332(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0004056"(argininosuccinate lyase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042450"(arginine biosynthetic process via ornithine)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000362(Fumarate lyase)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR009049(Argininosuccinate lyase)|interpro:IPR020557|interpro:IPR022761|interpro:IPR024083|interpro:IPR029419|rcsb pdb:1AOS|rcsb pdb:1K62|reactome:R-HSA-70635|entrezgene/locuslink:435(identity)	entrezgene/locuslink:79892(identity)	intact:EBI-16433007(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/jjoPEHb9KDFHkiMHccy73q2dGc9606	rogid:jlwzNIgLbSOvwlOEzQbiAfIAaM89606	rigid:o22mfKaQ3PC/gBanelJQGN7quF8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:P33993	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469659	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N|entrezgene/locuslink:4176(identity)	intact:EBI-16438686(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: MCM7_1 expression is provided in figureS2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606	rigid:UKrOJI8cGWl4ds7kKhcu/4qAO38	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BTE3-2	intact:EBI-16431221	intact:EBI-9384556|ensembl:ENSP00000358073	-	psi-mi:q9bte3-2(display_long)|uniprotkb:MCMBP(gene name)|psi-mi:MCMBP(display_short)|uniprotkb:C10orf119(gene name synonym)	psi-mi:"ccsb isoform id: mcm7_2"(display_short)|psi-mi:EBI-16431221(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469643	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-749378(isoform-parent)|uniprotkb:Q9BTE3-2(isoform-parent)|ensembl:ENSG00000197771(gene)|ensembl:ENST00000369077(transcript)|entrezgene/locuslink:79892(identity)	entrezgene/locuslink:4176(identity)	intact:EBI-16435274(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: MCM7_2 expression is provided in figureS2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nJOq6jis1maK+M/X0TcR44HlxRw9606	rogid:SqFBX8NXgEirtGEAtrDOEdPxPU89606	rigid:dIXZQfAFmfMP0OZbwm7bvY/ZzL0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NQM4	uniprotkb:P33993	intact:EBI-10239299|uniprotkb:Q86WE1|uniprotkb:D3DUX5|ensembl:ENSP00000337757|ensembl:ENSP00000361531|ensembl:ENSP00000441930	intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288	psi-mi:daaf6_human(display_long)|uniprotkb:DNAAF6(gene name)|psi-mi:DNAAF6(display_short)|uniprotkb:CXorf41(gene name synonym)|uniprotkb:PIH1 domain-containing protein 3(gene name synonym)|uniprotkb:PIH1D3(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-97(gene name synonym)	psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469627	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001162625.1|refseq:NP_775765.1|refseq:XP_011529157.1|ensembl:ENSG00000080572(gene)|ensembl:ENST00000336387(transcript)|ensembl:ENST00000372453(transcript)|ensembl:ENST00000535523(transcript)|go:"GO:0003341"(cilium movement)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0036158"(outer dynein arm assembly)|go:"GO:0036159"(inner dynein arm assembly)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070286"(axonemal dynein complex assembly)|interpro:IPR026697|interpro:IPR041442|entrezgene/locuslink:139212(identity)	refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N|entrezgene/locuslink:4176(identity)	intact:EBI-16434369(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: MCM7_1 expression is provided in figureS2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9mwmzVB9qiOuJQxcSddINet79iE9606	rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606	rigid:ai4LQIpw9uje25/3lxDN6Y4qQ1U	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P43360	uniprotkb:P33993	intact:EBI-1045155|uniprotkb:A8IF93|uniprotkb:Q6NW44|ensembl:ENSP00000329199|ensembl:ENSP00000480637	intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288	psi-mi:maga6_human(display_long)|uniprotkb:MAGE-6 antigen(gene name synonym)|uniprotkb:MAGE3B antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.6(gene name synonym)|uniprotkb:MAGEA6(gene name)|psi-mi:MAGEA6(display_short)|uniprotkb:MAGE6(gene name synonym)	psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469611	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005354.1|refseq:NP_787064.1|ensembl:ENSG00000197172(gene)|ensembl:ENST00000329342(transcript)|ensembl:ENST00000616035(transcript)|go:"GO:0010507"(negative regulation of autophagy)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030097|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4105(identity)	refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N|entrezgene/locuslink:4176(identity)	intact:EBI-16431223(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: MCM7_1 expression is provided in figureS2B."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Ag4IF8+k8aF+zuiB7NwjRrGGH6E9606	rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606	rigid:MXP+YjwUgwSzlYx7BcLr7pVYGAA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P62310	intact:EBI-16434023	intact:EBI-348239|ensembl:ENSP00000302160|uniprotkb:Q9Y4Z1|uniprotkb:Q6IAH0	-	psi-mi:lsm3_human(display_long)|uniprotkb:MDS017(orf name)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short)	psi-mi:"ccsb isoform id: lsm1_3"(display_short)|psi-mi:EBI-16434023(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469595	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000170860(gene)|ensembl:ENST00000306024(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030629"(U6 snRNA 3'-end binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|mint:P62310|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:NP_055278.1|dip:DIP-31218N|entrezgene/locuslink:27258(identity)	entrezgene/locuslink:27257(identity)	intact:EBI-16436871(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+OnRI9eJcsd1xJe+cUCP7Y/9tt09606	rogid:0XwAa+GObi6yt/UTcyBxxvUrqW09606	rigid:+08TQ0rQJoHqBsOS+S63ewpE1u4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P50221	uniprotkb:Q02078-6	intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684	intact:EBI-16437973|ensembl:ENSP00000337202|ensembl:ENSP00000453441	psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym)	psi-mi:q02078-6(display_long)|uniprotkb:Serum response factor-like protein 1(gene name synonym)|uniprotkb:MEF2A(gene name)|psi-mi:MEF2A(display_short)|uniprotkb:MEF2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469710	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity)	ensembl:ENSG00000068305(gene)|ensembl:ENST00000338042(transcript)|ensembl:ENST00000557785(transcript)|intact:EBI-2656305(isoform-parent)|entrezgene/locuslink:4205(identity)	intact:EBI-16431407(see-also)	-	isoform-comment:No experimental confirmation available. Contains a phosphoserine at position 98.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606	rogid:amqLoUTbFoxuByvSeiZrS7zXJRc9606	rigid:I/4qsh5j5GiGjRPFEPIVkcP/OzM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13164	intact:EBI-16469726	intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|intact:EBI-28979986|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968	-	psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym)	psi-mi:"ccsb isoform id: mef2a_5"(display_short)|psi-mi:EBI-16469726(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469729	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|ensembl:ENST00000299612|ensembl:ENSP00000299612|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968|refseq:XP_011522259.1|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|ensembl:ENSG00000166484(gene)|ensembl:ENST00000308406(transcript)|ensembl:ENST00000395602(transcript)|ensembl:ENST00000395604(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030154"(cell differentiation)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|entrezgene/locuslink:5598(identity)	entrezgene/locuslink:4205(identity)	intact:EBI-16437979(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606	rogid:Zyb8qTETXCdDyqhP6DLA9B0ZWyU9606	rigid:q8nRbJJ6IilcNnrH6E4vFcgWhKM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	intact:EBI-16469745	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	-	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469748	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16429183(see-also)|intact:EBI-16429193(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:c+4pheGSd14rM4+J6fXYk3Kem9c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	intact:EBI-16469745	intact:EBI-10172526|ensembl:ENSP00000413976	-	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469765	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16429468(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:oCPVLDzjCDnJhJohx2tDLNvaj4w	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13077	intact:EBI-16469745	intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183	-	psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469784	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956|entrezgene/locuslink:7185(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16430823(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:+pV9nU6WznCfgBsxc2xb08a0HdE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NHQ1	intact:EBI-16469745	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	-	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469800	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16432238(see-also)|intact:EBI-16432248(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:/Fl+Uydtdbu/uiwOEptFbxB178k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NA61-2	intact:EBI-16469745	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	-	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469817	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16432374(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:2pQI36dP6mTQO95RlD+F8DWxi9s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:Q9H7H0	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-749353|intact:EBI-948255|uniprotkb:Q9BSH1|uniprotkb:Q9BZH2|uniprotkb:Q9BZH3|ensembl:ENSP00000343041	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:met17_human(display_long)|uniprotkb:METT11D1(gene name synonym)|uniprotkb:Protein RSM22 homolog, mitochondrial(gene name synonym)|uniprotkb:METTL17(gene name)|psi-mi:METTL17(display_short)|uniprotkb:Methyltransferase 11 domain-containing protein 1(gene name synonym)|uniprotkb:False p73 target gene protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469833	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	refseq:NP_001025162.1|refseq:NP_073571.1|ensembl:ENSG00000165792(gene)|ensembl:ENST00000339374(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006412"(translation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR015324(Ribosomal protein Rsm22, bacterial-type)|interpro:IPR029063|mint:Q9H7H0|entrezgene/locuslink:64745(identity)	intact:EBI-16432374(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:RAj8jOqwthd7a0Xzi5FWhVKc8OI9606	rigid:5sB+y8Q6ab17+OOk+oAn/zIJcww	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13137	intact:EBI-16469745	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	-	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469849	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16433057(see-also)|intact:EBI-16433067(see-also)	crc64:609B121DA1A9DCB8	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:APpXW2U8lKd9qXsNeDYVnZbcjLA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	intact:EBI-16469745	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	-	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469866	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16435144(see-also)|intact:EBI-16435154(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:BGoFHOIeIMEYX0Hpv1Ro1DzAAgE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	intact:EBI-16469745	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	-	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469883	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16436091(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:dQ4U+TGlgqigz4PY5SEwdD3l05I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	intact:EBI-16469745	intact:EBI-16439278	-	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:"ccsb isoform id: mettl17_2"(display_short)|psi-mi:EBI-16469745(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469899	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	entrezgene/locuslink:64745(identity)	intact:EBI-16439599(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:uT1dtTkdfrpZul27BTW+kR8NpBg9606	rigid:yQrUCLhR275/2NMgWMcRth7S6/s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:Q9H7H0	intact:EBI-16439278	intact:EBI-749353|intact:EBI-948255|uniprotkb:Q9BSH1|uniprotkb:Q9BZH2|uniprotkb:Q9BZH3|ensembl:ENSP00000343041	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:met17_human(display_long)|uniprotkb:METT11D1(gene name synonym)|uniprotkb:Protein RSM22 homolog, mitochondrial(gene name synonym)|uniprotkb:METTL17(gene name)|psi-mi:METTL17(display_short)|uniprotkb:Methyltransferase 11 domain-containing protein 1(gene name synonym)|uniprotkb:False p73 target gene protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469915	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	refseq:NP_001025162.1|refseq:NP_073571.1|ensembl:ENSG00000165792(gene)|ensembl:ENST00000339374(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006412"(translation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR015324(Ribosomal protein Rsm22, bacterial-type)|interpro:IPR029063|mint:Q9H7H0|entrezgene/locuslink:64745(identity)	intact:EBI-16439599(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:RAj8jOqwthd7a0Xzi5FWhVKc8OI9606	rigid:20mDHO3cOxGtL6l+081R7o7eaT4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H892-2	uniprotkb:A0A0S2Z5W4	intact:EBI-10274410|ensembl:ENSP00000315160|ensembl:ENSP00000435291	intact:EBI-16469931	psi-mi:q9h892-2(display_long)|uniprotkb:TTC12(gene name)|psi-mi:TTC12(display_short)	psi-mi:a0a0s2z5w4_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469937	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000149292(gene)|ensembl:ENST00000314756(transcript)|ensembl:ENST00000494714(transcript)|intact:EBI-2548354(isoform-parent)|uniprotkb:Q9H892-2(isoform-parent)|entrezgene/locuslink:54970(identity)	interpro:IPR026175|entrezgene/locuslink:145282(identity)	intact:EBI-16440740(see-also)	isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OEjSVGC92wY/pn1l/B1t3wDa3s89606	rogid:3ejDpH+ibC5NXUABPjgilPVDuOA9606	rigid:01j3he4KV8yuWO6WFv9Jckhm0Ns	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H892-2	uniprotkb:A0A0S2Z674	intact:EBI-10274410|ensembl:ENSP00000315160|ensembl:ENSP00000435291	intact:EBI-16469953	psi-mi:q9h892-2(display_long)|uniprotkb:TTC12(gene name)|psi-mi:TTC12(display_short)	psi-mi:a0a0s2z674_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469959	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000149292(gene)|ensembl:ENST00000314756(transcript)|ensembl:ENST00000494714(transcript)|intact:EBI-2548354(isoform-parent)|uniprotkb:Q9H892-2(isoform-parent)|entrezgene/locuslink:54970(identity)	interpro:IPR026175|entrezgene/locuslink:145282(identity)	intact:EBI-16440740(see-also)	isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OEjSVGC92wY/pn1l/B1t3wDa3s89606	rogid:W+FeO28V8BN0eE1ebJT62PET4eQ9606	rigid:svcsSDHSgwkryM2lgzWuJbqTeEQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P43364	intact:EBI-16439609	intact:EBI-739552|uniprotkb:Q5ETU4|uniprotkb:Q6ZRZ5|ensembl:ENSP00000347358	-	psi-mi:magab_human(display_long)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)|uniprotkb:MAGE11(gene name synonym)|uniprotkb:MAGE-11 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.11(gene name synonym)	psi-mi:"ccsb isoform id: mlf1_5"(display_short)|psi-mi:EBI-16439609(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469975	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|refseq:NP_005357.2|ensembl:ENSG00000185247(gene)|ensembl:ENST00000355220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43364|rcsb pdb:6WJH|refseq:XP_016885010.1|refseq:XP_016885011.1|entrezgene/locuslink:4110(identity)	entrezgene/locuslink:4291(identity)	intact:EBI-16434491(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S0eOQssWhZCbAvWQCub2H+zQmzs9606	rogid:ZMtj2W+VOGl/FinhPqOSkd7clFg9606	rigid:RuwsOkEq4H9Sz3fz+9GZhyWyRYM	true	sufficient binding region:111-429	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:P58340	intact:EBI-16439278	intact:EBI-721328|intact:EBI-767466|uniprotkb:E9PEU9|uniprotkb:Q2TLE5|uniprotkb:Q8N8F8|uniprotkb:Q96MH1|uniprotkb:Q2TLE3|ensembl:ENSP00000348157	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:mlf1_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 1(gene name synonym)|uniprotkb:MLF1(gene name)|psi-mi:MLF1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16469994	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	refseq:NP_071888.1|refseq:NP_001182361.1|refseq:NP_001182362.1|refseq:NP_001182363.1|refseq:XP_011511154.1|refseq:NP_001123628.1|refseq:NP_001123629.1|ensembl:ENSP00000348157|ensembl:ENST00000359117|ensembl:ENSP00000352025|ensembl:ENST00000392822|ensembl:ENSP00000376568|ensembl:ENST00000469452|ensembl:ENSP00000418595|ensembl:ENST00000471745|ensembl:ENSP00000420134|ensembl:ENST00000477042|ensembl:ENSP00000419637|ensembl:ENST00000478894|ensembl:ENSP00000417777|ensembl:ENST00000482628|ensembl:ENSP00000417141|ensembl:ENST00000484955|ensembl:ENSP00000417835|ensembl:ENST00000618075|ensembl:ENSP00000484169|ensembl:ENST00000651874|ensembl:ENSP00000498363|refseq:XP_011511155.1|refseq:XP_005247537.1|ensembl:ENSG00000178053(gene)|ensembl:ENST00000355893(transcript)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR019376|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6Y8E|entrezgene/locuslink:4291(identity)	intact:EBI-16439611(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:czY64xaocTjgRFAtZU19jvH4MIo9606	rigid:sFu5Ult2L5Eh5EF0jhwiWPkqwFs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z414	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16470010	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z414_human(display_long)|uniprotkb:MNAT1(gene name)|psi-mi:MNAT1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470013	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0005694"(chromosome)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|entrezgene/locuslink:4331(identity)	intact:EBI-16438504(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:A3QD1f7tkTcEwQiMnqHb9RjcmYQ9606	rigid:KtcEI8qUAWlXyqSkM6pgDWn5kmI	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16434391	uniprotkb:Q13875-3	-	intact:EBI-12013470|ensembl:ENSP00000373261|ensembl:ENSP00000388148|ensembl:ENSP00000401312|ensembl:ENSP00000405549|ensembl:ENSP00000409730	psi-mi:"ccsb orf id: 4214"(display_short)|psi-mi:EBI-16434391(display_long)	psi-mi:q13875-3(display_long)|uniprotkb:MOBP(gene name)|psi-mi:MOBP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470032	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:51322(identity)	intact:EBI-10230628(isoform-parent)|ensembl:ENSG00000168314(gene)|ensembl:ENST00000383754(transcript)|ensembl:ENST00000415443(transcript)|ensembl:ENST00000428261(transcript)|ensembl:ENST00000447324(transcript)|ensembl:ENST00000452959(transcript)|uniprotkb:Q13875-3(isoform-parent)|uniprotkb:Q13875(isoform-parent)|entrezgene/locuslink:4336(identity)	intact:EBI-16434393(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1lJ64iBkqUGKNB4Lz3jsp7Xu2nE9606	rogid:5ggi9FWhAQgAnqMbLGQbSC+v4049606	rigid:sMEq5sDRgc1BIo/pVMobTPUDwwY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N0S2	uniprotkb:A0A0S2Z469	intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3	intact:EBI-16470048	psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short)	psi-mi:a0a0s2z469_human(display_long)|uniprotkb:MPV17(gene name)|psi-mi:MPV17(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470055	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1|entrezgene/locuslink:93426(identity)	go:"GO:0016021"(integral component of membrane)|interpro:IPR007248(Mpv17/PMP22)|entrezgene/locuslink:4358(identity)	intact:EBI-16440288(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606	rogid:JSwozIrhGB4JPZnxPDsiRGVjL+89606	rigid:8lLiIwAHlHeqFUi3K8+gmslds10	true	sufficient binding region:37-351	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q03426	uniprotkb:F5H8H2	intact:EBI-740630|ensembl:ENSP00000228510|ensembl:ENSP00000443551	intact:EBI-16470096|ensembl:ENSP00000376487|ensembl:ENSP00000486846	psi-mi:kime_human(display_long)|uniprotkb:MVK(gene name)|psi-mi:MVK(display_short)	psi-mi:f5h8h2_human(display_long)|uniprotkb:MVK(gene name)|psi-mi:MVK(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470118	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001288111.1|ensembl:ENSG00000110921(gene)|ensembl:ENST00000228510(transcript)|ensembl:ENST00000539575(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004496"(mevalonate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0019287"(isopentenyl diphosphate biosynthetic process, mevalonate pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050728"(negative regulation of inflammatory response)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006205(Mevalonate kinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR036554|rcsb pdb:2R3V|reactome:R-HSA-191273|reactome:R-HSA-2426168|refseq:NP_000422.1|refseq:NP_001107657.1|refseq:XP_016874803.1|entrezgene/locuslink:4598(identity)	ensembl:ENSG00000110921(gene)|ensembl:ENST00000392727(transcript)|ensembl:ENST00000625889(transcript)|go:"GO:0004496"(mevalonate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0019287"(isopentenyl diphosphate biosynthetic process, mevalonate pathway)|interpro:IPR006204(GHMP kinase)|interpro:IPR006205(Mevalonate kinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR036554|refseq:NP_001288111.1|refseq:XP_016874802.1|entrezgene/locuslink:4598(identity)	intact:EBI-16433177(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aNoNx1GxznUy5Sha8pg9q6SK5lw9606	rogid:QARRM7Sfrh7jiH0zmK2l+jxt+QI9606	rigid:uqdqbhKldFKUClmHgdG1q0l8Ass	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N0S2	uniprotkb:A0A0S2Z466	intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3	intact:EBI-16470074	psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short)	psi-mi:a0a0s2z466_human(display_long)|uniprotkb:MPV17(gene name)|psi-mi:MPV17(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470077	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1|entrezgene/locuslink:93426(identity)	entrezgene/locuslink:4358(identity)	intact:EBI-16440288(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606	rogid:wN9MhGWk8flcmGtr/0RWiUlpcEM9606	rigid:oqCM61cj5e7y3d1o4ARPwMmX9UU	true	sufficient binding region:37-351	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HB07	uniprotkb:A0A0S2Z442	intact:EBI-709754|ensembl:ENSP00000267103|uniprotkb:Q86UA3|intact:EBI-10258793	intact:EBI-16435864	psi-mi:myg1_human(display_long)|uniprotkb:MYG1(gene name)|psi-mi:MYG1(display_short)|uniprotkb:C12orf10(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470699	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139637(gene)|ensembl:ENST00000267103(transcript)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0035641"(locomotory exploration behavior)|interpro:IPR003226(Metal-dependent protein hydrolase)|mint:Q9HB07|refseq:NP_067653.3|entrezgene/locuslink:60314(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429853(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/18	rogid:k6ea0h/OMRODp3PQjed6sdxw44I9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:jSjRfyqDbFwiXsH6TXLS2TQQyA4	true	sufficient binding region:156-376	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HB07	uniprotkb:A0A0S2Z3Y6	intact:EBI-709754|ensembl:ENSP00000267103|uniprotkb:Q86UA3|intact:EBI-10258793	intact:EBI-16435852	psi-mi:myg1_human(display_long)|uniprotkb:MYG1(gene name)|psi-mi:MYG1(display_short)|uniprotkb:C12orf10(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470680	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139637(gene)|ensembl:ENST00000267103(transcript)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0035641"(locomotory exploration behavior)|interpro:IPR003226(Metal-dependent protein hydrolase)|mint:Q9HB07|refseq:NP_067653.3|entrezgene/locuslink:60314(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429853(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/18	rogid:k6ea0h/OMRODp3PQjed6sdxw44I9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:WuDbM+/C6DnUkGotxqXQll9zlvA	true	sufficient binding region:156-376	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:I6L9F6	uniprotkb:A0A0S2Z3Z2	intact:EBI-10178578|intact:EBI-21999896	intact:EBI-16470607	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470664	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429843(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:Xb9uUHPqxlN/6C8piYbCyb381t4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:I6L9F6	uniprotkb:A0A0S2Z442	intact:EBI-10178578|intact:EBI-21999896	intact:EBI-16435864	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470648	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429843(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:N4j7TlsIbAF5/Cy9XQP72ATsh9Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:I6L9F6	uniprotkb:A0A0S2Z3Y6	intact:EBI-10178578|intact:EBI-21999896	intact:EBI-16435852	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470632	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429843(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:GoqpYqO+OMp0FHa5qk9j488CwkA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:A0A0S2Z3Z2	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-16470607	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470616	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429057(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:YTLpq1Knw/S8c88BWpHrRytf5lk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:A0A0S2Z442	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-16435864	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470591	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429057(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:4kuxEZ0wVittNCmgL7YpvAJonME	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:A0A0S2Z3Y6	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-16435852	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470575	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429057(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:OIo+ShkxGvm5lfSMs4eBirlq7P0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:E7ERP6	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-16429362|ensembl:ENSP00000410428|ensembl:ENSP00000431109	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:e7erp6_human(display_long)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470559	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	ensembl:ENSG00000071051(gene)|ensembl:ENST00000451463(transcript)|ensembl:ENST00000522586(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030222|interpro:IPR036028|interpro:IPR039801|refseq:NP_001004722.1|refseq:XP_011510294.2|entrezgene/locuslink:8440(identity)	intact:EBI-16438716(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:4MirIo4vpZDMGWlDnofHnGzCUJ89606	rigid:UTKF+NwN5khzlfjxhnrXC8lSsAw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13191	uniprotkb:E7ERP6	intact:EBI-744027|uniprotkb:Q63Z43|uniprotkb:A8K9S7|uniprotkb:Q13192|uniprotkb:Q13193|uniprotkb:Q3LIC0|uniprotkb:Q8IVC5|uniprotkb:B7WNM4|intact:EBI-28969458|ensembl:ENSP00000377598|intact:EBI-8051403|intact:MINT-7907019	intact:EBI-16429362|ensembl:ENSP00000410428|ensembl:ENSP00000431109	psi-mi:cblb_human(display_long)|uniprotkb:Signal transduction protein CBL-B(gene name synonym)|uniprotkb:SH3-binding protein CBL-B(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene b(gene name synonym)|uniprotkb:RING finger protein 56(gene name synonym)|uniprotkb:CBLB(gene name)|psi-mi:CBLB(display_short)|uniprotkb:RNF56(gene name synonym)|uniprotkb:Nbla00127(orf name)|uniprotkb:RING-type E3 ubiquitin transferase CBL-B(gene name synonym)	psi-mi:e7erp6_human(display_long)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470543	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_733762.2|refseq:NP_001308717.1|ensembl:ENSP00000377598|ensembl:ENST00000403724|ensembl:ENSP00000384816|ensembl:ENST00000405772|ensembl:ENSP00000384938|refseq:XP_011511559.1|ensembl:ENSG00000114423(gene)|ensembl:ENST00000394030(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018193"(peptidyl-amino acid modification)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042110"(T cell activation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:Q13191|rcsb pdb:2AK5|rcsb pdb:2BZ8|rcsb pdb:2DO6|rcsb pdb:2J6F|rcsb pdb:2JNH|rcsb pdb:2LDR|rcsb pdb:2OOA|rcsb pdb:2OOB|rcsb pdb:3PFV|rcsb pdb:3VGO|rcsb pdb:3ZNI|reactome:R-HSA-983168|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|dip:DIP-33091N|entrezgene/locuslink:868(identity)	ensembl:ENSG00000071051(gene)|ensembl:ENST00000451463(transcript)|ensembl:ENST00000522586(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030222|interpro:IPR036028|interpro:IPR039801|refseq:NP_001004722.1|refseq:XP_011510294.2|entrezgene/locuslink:8440(identity)	intact:EBI-16432612(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:cJ5eLH0TMyM6OtmS1sM3rhsrsIk9606	rogid:4MirIo4vpZDMGWlDnofHnGzCUJ89606	rigid:SMSIHxvJ8eIs+x5jb3fFHgrL2As	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:A6PVS8	uniprotkb:E7ERP6	intact:EBI-10184751|uniprotkb:Q6P5P7|uniprotkb:A6PVS9|uniprotkb:Q8WUE0|uniprotkb:Q6ZMV4|ensembl:ENSP00000346414|ensembl:ENSP00000378524	intact:EBI-16429362|ensembl:ENSP00000410428|ensembl:ENSP00000431109	psi-mi:lriq3_human(display_long)|uniprotkb:LRRIQ3(gene name)|psi-mi:LRRIQ3(display_short)|uniprotkb:LRRC44(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 44(gene name synonym)	psi-mi:e7erp6_human(display_long)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470524	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001099129.1|ensembl:ENSG00000162620(gene)|ensembl:ENST00000354431(transcript)|ensembl:ENST00000395089(transcript)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR032675|entrezgene/locuslink:127255(identity)	ensembl:ENSG00000071051(gene)|ensembl:ENST00000451463(transcript)|ensembl:ENST00000522586(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030222|interpro:IPR036028|interpro:IPR039801|refseq:NP_001004722.1|refseq:XP_011510294.2|entrezgene/locuslink:8440(identity)	intact:EBI-16431818(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:tKMDvvd6Ewj8c0zCALo+pv6+el89606	rogid:4MirIo4vpZDMGWlDnofHnGzCUJ89606	rigid:Z1GXHWl+OzewT4eDVnDB6NPzmlk	true	sufficient binding region:404-624	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BRK4	uniprotkb:E7ERP6	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	intact:EBI-16429362|ensembl:ENSP00000410428|ensembl:ENSP00000431109	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:e7erp6_human(display_long)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470508	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	ensembl:ENSG00000071051(gene)|ensembl:ENST00000451463(transcript)|ensembl:ENST00000522586(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030222|interpro:IPR036028|interpro:IPR039801|refseq:NP_001004722.1|refseq:XP_011510294.2|entrezgene/locuslink:8440(identity)	intact:EBI-16430556(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	rogid:4MirIo4vpZDMGWlDnofHnGzCUJ89606	rigid:Vlh3x4+vOEhpTDE3+X3NiJW8j8E	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13094	uniprotkb:E7ERP6	intact:EBI-346946|uniprotkb:Q53XV4|uniprotkb:A8KA25|ensembl:ENSP00000046794	intact:EBI-16429362|ensembl:ENSP00000410428|ensembl:ENSP00000431109	psi-mi:lcp2_human(display_long)|uniprotkb:LCP2(gene name)|psi-mi:LCP2(display_short)|uniprotkb:SH2 domain-containing leukocyte protein of 76 kDa(gene name synonym)|uniprotkb:SLP-76 tyrosine phosphoprotein(gene name synonym)	psi-mi:e7erp6_human(display_long)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470492	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005556.1|dip:DIP-31812N|ensembl:ENSG00000043462(gene)|ensembl:ENST00000046794(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036398"(TCR signalosome)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045576"(mast cell activation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000980(SH2 motif)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036860|mint:Q13094|rcsb pdb:1H3H|rcsb pdb:1YWO|rcsb pdb:2EAP|rcsb pdb:2ROR|rcsb pdb:6ZCJ|reactome:R-HSA-114604|reactome:R-HSA-202433|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|entrezgene/locuslink:3937(identity)	ensembl:ENSG00000071051(gene)|ensembl:ENST00000451463(transcript)|ensembl:ENST00000522586(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030222|interpro:IPR036028|interpro:IPR039801|refseq:NP_001004722.1|refseq:XP_011510294.2|entrezgene/locuslink:8440(identity)	intact:EBI-16430051(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:lZa+nAuqvGDrNe3Jhxn/JQaU5ug9606	rogid:4MirIo4vpZDMGWlDnofHnGzCUJ89606	rigid:mFHT8DhRg5rm3Ofb3ypiuwbjCcE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P48023	uniprotkb:A0A0S2Z4E4	intact:EBI-495538|uniprotkb:Q9BZP9|ensembl:ENSP00000356694	intact:EBI-16432934	psi-mi:tnfl6_human(display_long)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:CD95L(gene name synonym)|uniprotkb:Apoptosis antigen ligand(gene name synonym)|uniprotkb:FASLG(gene name)|psi-mi:FASLG(display_short)|uniprotkb:APT1LG1(gene name synonym)|uniprotkb:FASL(gene name synonym)|uniprotkb:TNFSF6(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:a0a0s2z4e4_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470476	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000630.1|refseq:NP_001289675.1|dip:DIP-2997N|ensembl:ENSG00000117560(gene)|ensembl:ENST00000367721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|mint:P48023|rcsb pdb:1BZI|rcsb pdb:4MSV|rcsb pdb:5L19|rcsb pdb:5L36|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6785807|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-8862803|reactome:R-HSA-9614657|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|entrezgene/locuslink:356(identity)	interpro:IPR035562|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR028526|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:4690(identity)	intact:EBI-16438840(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:jz8jH0vq1IWFKlMxIBl83KGgXoE9606	rigid:uAFKSL/tdogltHdlU75kSFmdTh8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P48023	uniprotkb:P16333	intact:EBI-495538|uniprotkb:Q9BZP9|ensembl:ENSP00000356694	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:tnfl6_human(display_long)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:CD95L(gene name synonym)|uniprotkb:Apoptosis antigen ligand(gene name synonym)|uniprotkb:FASLG(gene name)|psi-mi:FASLG(display_short)|uniprotkb:APT1LG1(gene name synonym)|uniprotkb:FASL(gene name synonym)|uniprotkb:TNFSF6(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470460	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000630.1|refseq:NP_001289675.1|dip:DIP-2997N|ensembl:ENSG00000117560(gene)|ensembl:ENST00000367721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|mint:P48023|rcsb pdb:1BZI|rcsb pdb:4MSV|rcsb pdb:5L19|rcsb pdb:5L36|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6785807|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-8862803|reactome:R-HSA-9614657|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|entrezgene/locuslink:356(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16438840(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:4wlsxTeTgH4bxnTfUv4IhlAUSdU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:P16333	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470443	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16438696(see-also)|intact:EBI-16438706(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:x9YY/TRt5pxM+zUMiwe6vlUM2OY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O60504	uniprotkb:A0A0S2Z4E4	intact:EBI-741237|ensembl:ENSP00000240123|uniprotkb:Q5BJE4|uniprotkb:Q6NX54|uniprotkb:Q9UQE4|intact:EBI-1222937|uniprotkb:Q96FY4	intact:EBI-16432934	psi-mi:vinex_human(display_long)|uniprotkb:SCAM1(gene name synonym)|uniprotkb:SH3-containing adapter molecule 1(gene name synonym)|uniprotkb:Sorbin and SH3 domain-containing protein 3(gene name synonym)|uniprotkb:SORBS3(gene name)|psi-mi:SORBS3(display_short)	psi-mi:a0a0s2z4e4_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470427	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120896(gene)|ensembl:ENST00000240123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0017166"(vinculin binding)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR028510|interpro:IPR035607|interpro:IPR035608|interpro:IPR035609|interpro:IPR036028|mint:O60504|rcsb pdb:2CT3|rcsb pdb:2DLM|rcsb pdb:2NWM|rcsb pdb:2YUP|reactome:R-HSA-445355|refseq:NP_001018003.1|refseq:NP_005766.3|refseq:XP_005273428.1|refseq:XP_016868433.1|refseq:XP_016868434.1|refseq:XP_016868435.1|entrezgene/locuslink:10174(identity)	interpro:IPR035562|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR028526|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:4690(identity)	intact:EBI-16436478(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Mq3VXduU/1gqfUwliO9sBBOb/Vc9606	rogid:jz8jH0vq1IWFKlMxIBl83KGgXoE9606	rigid:Wf1uzrybzAXR1LzrSPjLOkeI7vQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O60504	uniprotkb:P16333	intact:EBI-741237|ensembl:ENSP00000240123|uniprotkb:Q5BJE4|uniprotkb:Q6NX54|uniprotkb:Q9UQE4|intact:EBI-1222937|uniprotkb:Q96FY4	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:vinex_human(display_long)|uniprotkb:SCAM1(gene name synonym)|uniprotkb:SH3-containing adapter molecule 1(gene name synonym)|uniprotkb:Sorbin and SH3 domain-containing protein 3(gene name synonym)|uniprotkb:SORBS3(gene name)|psi-mi:SORBS3(display_short)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470411	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120896(gene)|ensembl:ENST00000240123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0017166"(vinculin binding)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR028510|interpro:IPR035607|interpro:IPR035608|interpro:IPR035609|interpro:IPR036028|mint:O60504|rcsb pdb:2CT3|rcsb pdb:2DLM|rcsb pdb:2NWM|rcsb pdb:2YUP|reactome:R-HSA-445355|refseq:NP_001018003.1|refseq:NP_005766.3|refseq:XP_005273428.1|refseq:XP_016868433.1|refseq:XP_016868434.1|refseq:XP_016868435.1|entrezgene/locuslink:10174(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16436478(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Mq3VXduU/1gqfUwliO9sBBOb/Vc9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:I4uCeo4E/G8vGrD0IMgM7xlXbDc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:A0A0C3SFZ9	uniprotkb:P16333	intact:EBI-11977403|ensembl:ENSP00000473001	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:a0a0c3sfz9_human(display_long)|uniprotkb:FCHO1(gene name)|psi-mi:FCHO1(display_short)|uniprotkb:hCG_2000568(orf name)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470395	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000130475(gene)|ensembl:ENST00000594202(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|interpro:IPR030121|interpro:IPR031160|interpro:IPR042735|go:"GO:0005829"(cytosol)|refseq:NP_001154829.1|entrezgene/locuslink:23149(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16436448(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:YfVbZHntDpLjsmnH0GM2eaqEGjY9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:eDeiXjBy+He+BuOAMKbvG6mviMU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16436244	uniprotkb:A0A0S2Z4E4	-	intact:EBI-16432934	psi-mi:"ccsb orf id: 54692"(display_short)|psi-mi:EBI-16436244(display_long)	psi-mi:a0a0s2z4e4_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470379	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:57594(identity)	interpro:IPR035562|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR028526|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:4690(identity)	intact:EBI-16436266(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:pQLRUATtfhRxD9ugVFmKu+SJGB89606	rogid:jz8jH0vq1IWFKlMxIBl83KGgXoE9606	rigid:jE/cw+SX7GCVty4cbfcqtDzUYdo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16436244	uniprotkb:P16333	-	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:"ccsb orf id: 54692"(display_short)|psi-mi:EBI-16436244(display_long)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470363	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:57594(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16436266(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:pQLRUATtfhRxD9ugVFmKu+SJGB89606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:GJPGM470jq0/0dfrDmntV0/qtY4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:B7ZLH0	uniprotkb:A0A0S2Z4E4	intact:EBI-10220102|intact:EBI-11975495|intact:EBI-12742387	intact:EBI-16432934	psi-mi:b7zlh0_human(display_long)|uniprotkb:FAM22F(gene name)|psi-mi:FAM22F(display_short)	psi-mi:a0a0s2z4e4_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470347	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR024309|interpro:IPR024310|entrezgene/locuslink:54754(identity)	interpro:IPR035562|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR028526|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:4690(identity)	intact:EBI-16436234(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:0MIH/bAcmcr+6BUiuF4G+9qCEEE9606	rogid:jz8jH0vq1IWFKlMxIBl83KGgXoE9606	rigid:aGXhP/KV6A4wlPTFn+r36fpgAZw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:B7ZLH0	uniprotkb:P16333	intact:EBI-10220102|intact:EBI-11975495|intact:EBI-12742387	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:b7zlh0_human(display_long)|uniprotkb:FAM22F(gene name)|psi-mi:FAM22F(display_short)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470331	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR024309|interpro:IPR024310|entrezgene/locuslink:54754(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16436234(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:0MIH/bAcmcr+6BUiuF4G+9qCEEE9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:DeMqfVFzzvr3oPz65o2pJ0gpslo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96IJ6	uniprotkb:A0A0S2Z4E4	intact:EBI-750953|uniprotkb:A6NJ74|uniprotkb:A8K3Q6|uniprotkb:Q53GI0|uniprotkb:Q9NWC3|uniprotkb:Q9Y5P5|uniprotkb:B3KMT4|ensembl:ENSP00000315925|ensembl:ENSP00000340760|ensembl:ENSP00000350949|ensembl:ENSP00000363016|ensembl:ENSP00000478700|ensembl:ENSP00000506941	intact:EBI-16432934	psi-mi:gmppa_human(display_long)|uniprotkb:GMPPA(gene name)|psi-mi:GMPPA(display_short)|uniprotkb:GTP-mannose-1-phosphate guanylyltransferase alpha(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase A(gene name synonym)	psi-mi:a0a0s2z4e4_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470315	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037467.2|refseq:NP_995319.1|refseq:XP_005246543.1|refseq:XP_016859398.1|refseq:XP_016859399.1|refseq:XP_016859400.1|ensembl:ENSG00000144591(gene)|ensembl:ENST00000313597(transcript)|ensembl:ENST00000341142(transcript)|ensembl:ENST00000358215(transcript)|ensembl:ENST00000373908(transcript)|ensembl:ENST00000622191(transcript)|ensembl:ENST00000683946(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|mint:Q96IJ6|rcsb pdb:7D72|rcsb pdb:7D73|rcsb pdb:7D74|reactome:R-HSA-446205|entrezgene/locuslink:29926(identity)	interpro:IPR035562|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR028526|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:4690(identity)	intact:EBI-16434569(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ASWzJoQB8W+e2OKYEenXpUJxflI9606	rogid:jz8jH0vq1IWFKlMxIBl83KGgXoE9606	rigid:CenXYIo74famgMzD41k/PsIs35o	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96IJ6	uniprotkb:P16333	intact:EBI-750953|uniprotkb:A6NJ74|uniprotkb:A8K3Q6|uniprotkb:Q53GI0|uniprotkb:Q9NWC3|uniprotkb:Q9Y5P5|uniprotkb:B3KMT4|ensembl:ENSP00000315925|ensembl:ENSP00000340760|ensembl:ENSP00000350949|ensembl:ENSP00000363016|ensembl:ENSP00000478700|ensembl:ENSP00000506941	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:gmppa_human(display_long)|uniprotkb:GMPPA(gene name)|psi-mi:GMPPA(display_short)|uniprotkb:GTP-mannose-1-phosphate guanylyltransferase alpha(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase A(gene name synonym)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470299	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037467.2|refseq:NP_995319.1|refseq:XP_005246543.1|refseq:XP_016859398.1|refseq:XP_016859399.1|refseq:XP_016859400.1|ensembl:ENSG00000144591(gene)|ensembl:ENST00000313597(transcript)|ensembl:ENST00000341142(transcript)|ensembl:ENST00000358215(transcript)|ensembl:ENST00000373908(transcript)|ensembl:ENST00000622191(transcript)|ensembl:ENST00000683946(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|mint:Q96IJ6|rcsb pdb:7D72|rcsb pdb:7D73|rcsb pdb:7D74|reactome:R-HSA-446205|entrezgene/locuslink:29926(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16434569(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ASWzJoQB8W+e2OKYEenXpUJxflI9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:BOXpuyxBW2RxwkpFnIt9wPZj5xA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43281-2	uniprotkb:P16333	intact:EBI-11525448|ensembl:ENSP00000340607	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:o43281-2(display_long)|uniprotkb:CASS3(gene name synonym)|uniprotkb:Cas scaffolding protein family member 3(gene name synonym)|uniprotkb:EFS(gene name)|psi-mi:EFS(display_short)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470282	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-718488(isoform-parent)|ensembl:ENSG00000100842(gene)|ensembl:ENST00000351354(transcript)|uniprotkb:O43281-2(isoform-parent)|entrezgene/locuslink:10278(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16432924(see-also)|intact:EBI-16432941(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JdV6uL2+FglKvl/B+OVXk/eIIKQ9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:Ue22dEliW3KgLlZrqlU1CDNleUc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00401	uniprotkb:A0A0S2Z4E4	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	intact:EBI-16432934	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:a0a0s2z4e4_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470266	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N|entrezgene/locuslink:8976(identity)	interpro:IPR035562|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR028526|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|entrezgene/locuslink:4690(identity)	intact:EBI-16429342(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	rogid:jz8jH0vq1IWFKlMxIBl83KGgXoE9606	rigid:j4wkcZae4jxzlwhg2a0wp2/w6tQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00401	uniprotkb:P16333	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470250	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N|entrezgene/locuslink:8976(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|entrezgene/locuslink:4690(identity)	intact:EBI-16429342(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rigid:lqCI+ofXwzz8oM7+qVUNjwqgiuw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q92845	intact:EBI-16470212	intact:EBI-954040|ensembl:ENSP00000354560|uniprotkb:Q8NHU7|uniprotkb:Q9H416|uniprotkb:B2RDL1|uniprotkb:B1AKU4|uniprotkb:B7Z8A3|uniprotkb:F5H591|uniprotkb:B1AKU5	-	psi-mi:kifa3_human(display_long)|uniprotkb:Smg GDS-associated protein(gene name synonym)|uniprotkb:KIFAP3(gene name)|psi-mi:KIFAP3(display_short)|uniprotkb:SMAP(gene name synonym)|uniprotkb:KIF3AP(gene name synonym)	psi-mi:"ccsb isoform id: ncf2_3"(display_short)|psi-mi:EBI-16470212(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470234	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000075945(gene)|ensembl:ENST00000361580(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016939"(kinesin II complex)|go:"GO:0019894"(kinesin binding)|go:"GO:1990075"(periciliary membrane compartment)|interpro:IPR000225(Armadillo)|go:"GO:0019903"(protein phosphatase binding)|interpro:IPR008658(Kinesin-associated)|interpro:IPR016024(Armadillo-type fold)|reactome:R-HSA-1445148|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035869"(ciliary transition zone)|reactome:R-HSA-2132295|reactome:R-HSA-5620924|go:"GO:0036064"(ciliary basal body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044782"(cilium organization)|go:"GO:0046587"(positive regulation of calcium-dependent cell-cell adhesion)|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0097542"(ciliary tip)|go:"GO:0120170"(intraciliary transport particle B binding)|refseq:NP_001191443.1|refseq:NP_001191445.1|refseq:NP_001191446.1|refseq:NP_055785.2|entrezgene/locuslink:22920(identity)	entrezgene/locuslink:4688(identity)	intact:EBI-16432208(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:pEcMuA/HlGJKpLQzlt1/R00TZ3Q9606	rogid:XHifaKiQX9T73M8hI3zbprOvASg9606	rigid:gRX/2d+g9jgtNS4XYuuN0OtCSok	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	intact:EBI-16470212	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	-	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"ccsb isoform id: ncf2_3"(display_short)|psi-mi:EBI-16470212(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470215	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	entrezgene/locuslink:4688(identity)	intact:EBI-16431890(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:XHifaKiQX9T73M8hI3zbprOvASg9606	rigid:mzuItcr2fPE1sjLqbGj9Mu5ukUs	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P12814	uniprotkb:Q9UBF9	intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403	intact:EBI-296701|uniprotkb:A0A4R6|uniprotkb:B4DT79	psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:myoti_human(display_long)|uniprotkb:MYOT(gene name)|psi-mi:MYOT(display_short)|uniprotkb:TTID(gene name synonym)|uniprotkb:Titin immunoglobulin domain protein(gene name synonym)|uniprotkb:Myofibrillar titin-like Ig domains protein(gene name synonym)|uniprotkb:57 kDa cytoskeletal protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470196	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001093.1|refseq:NP_001123477.1|refseq:NP_001123476.1|dip:DIP-33184N|ensembl:ENSG00000072110(gene)|ensembl:ENST00000193403(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034|entrezgene/locuslink:87(identity)	go:"GO:0030424"(axon)|go:"GO:0042383"(sarcolemma)|go:"GO:0043025"(neuronal cell body)|go:"GO:0050808"(synapse organization)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0030018"(Z disc)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001129412.1|refseq:NP_006781.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|rcsb pdb:2KDG|rcsb pdb:2KKQ|refseq:NP_001287840.1|interpro:IPR036179|entrezgene/locuslink:9499(identity)	intact:EBI-16433911(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:guTURyt26f1ort4NAlYyabNc+WE9606	rogid:y7p/HY416pf0hNjpo0B5cRolBAk9606	rigid:bPkL3/qVP9rAJ+56DZMs54ZxeYs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:A0A0S2Z429	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-16470161|ensembl:ENSP00000498474	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:a0a0s2z429_human(display_long)|uniprotkb:MXI1(gene name)|psi-mi:MXI1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470180	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	ensembl:ENSG00000119950(gene)|ensembl:ENST00000651557(transcript)|entrezgene/locuslink:4601(identity)	intact:EBI-16439829(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:GxWoSYidUugRrliIv8jOCRLaqec9606	rigid:We5nCqyAcseJwfFSxlKThfrGeRs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	uniprotkb:A0A0S2Z429	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	intact:EBI-16470161|ensembl:ENSP00000498474	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:a0a0s2z429_human(display_long)|uniprotkb:MXI1(gene name)|psi-mi:MXI1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470164	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	ensembl:ENSG00000119950(gene)|ensembl:ENST00000651557(transcript)|entrezgene/locuslink:4601(identity)	intact:EBI-16436117(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:GxWoSYidUugRrliIv8jOCRLaqec9606	rigid:+byfwSBoGfuWEiylGHDnE40/CV0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WVE0	uniprotkb:A0A0S2Z3Y6	intact:EBI-16430415|ensembl:ENSP00000372202|ensembl:ENSP00000372206|uniprotkb:B5G4V1	intact:EBI-16435852	psi-mi:efmt1_human(display_long)|uniprotkb:"N(6)-adenine-specific DNA methyltransferase 2"(gene name synonym)|uniprotkb:Protein-lysine N-methyltransferase N6AMT2(gene name synonym)|uniprotkb:EEF1AKMT1(gene name)|psi-mi:EEF1AKMT1(display_short)|uniprotkb:N6AMT2(gene name synonym)|uniprotkb:eEF1A-KMT(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470753	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150456(gene)|ensembl:ENST00000382754(transcript)|ensembl:ENST00000382758(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018022"(peptidyl-lysine methylation)|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR019369|interpro:IPR029063|interpro:IPR041370|reactome:R-HSA-8876725|refseq:NP_001305868.1|refseq:NP_777588.1|refseq:XP_016875921.1|entrezgene/locuslink:221143(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430440(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qKNqMbQPejzDNq5IswwsVDIUopY9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:xIi4jLqGVri0ZDYas3uvhZkiyAE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WVE0	uniprotkb:Q99608	intact:EBI-16430415|ensembl:ENSP00000372202|ensembl:ENSP00000372206|uniprotkb:B5G4V1	intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916	psi-mi:efmt1_human(display_long)|uniprotkb:"N(6)-adenine-specific DNA methyltransferase 2"(gene name synonym)|uniprotkb:Protein-lysine N-methyltransferase N6AMT2(gene name synonym)|uniprotkb:EEF1AKMT1(gene name)|psi-mi:EEF1AKMT1(display_short)|uniprotkb:N6AMT2(gene name synonym)|uniprotkb:eEF1A-KMT(gene name synonym)	psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470737	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150456(gene)|ensembl:ENST00000382754(transcript)|ensembl:ENST00000382758(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018022"(peptidyl-lysine methylation)|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR019369|interpro:IPR029063|interpro:IPR041370|reactome:R-HSA-8876725|refseq:NP_001305868.1|refseq:NP_777588.1|refseq:XP_016875921.1|entrezgene/locuslink:221143(identity)	refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity)	intact:EBI-16430440(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qKNqMbQPejzDNq5IswwsVDIUopY9606	rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606	rigid:F0O+chgUWIVbxDe6PC02n/pi9kM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HB07	uniprotkb:A0A0S2Z3Z2	intact:EBI-709754|ensembl:ENSP00000267103|uniprotkb:Q86UA3|intact:EBI-10258793	intact:EBI-16470607	psi-mi:myg1_human(display_long)|uniprotkb:MYG1(gene name)|psi-mi:MYG1(display_short)|uniprotkb:C12orf10(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470718	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139637(gene)|ensembl:ENST00000267103(transcript)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0035641"(locomotory exploration behavior)|interpro:IPR003226(Metal-dependent protein hydrolase)|mint:Q9HB07|refseq:NP_067653.3|entrezgene/locuslink:60314(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16429853(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/18	rogid:k6ea0h/OMRODp3PQjed6sdxw44I9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:5woGWhpP0CAQzSXoPaX+o/YYnsU	true	sufficient binding region:156-376	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IWV1-3	uniprotkb:A0A0S2Z3Z2	intact:EBI-12327415|ensembl:ENSP00000356186	intact:EBI-16470607	psi-mi:q8iwv1-3(display_long)|uniprotkb:LAX1(gene name)|psi-mi:LAX1(display_short)|uniprotkb:LAX(gene name synonym)|uniprotkb:Linker for activation of X cells(gene name synonym)|uniprotkb:Membrane-associated adapter protein LAX(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470992	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10232942(isoform-parent)|ensembl:ENSG00000122188(gene)|ensembl:ENST00000367217(transcript)|uniprotkb:Q8IWV1-3(isoform-parent)|entrezgene/locuslink:54900(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16431471(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fIN9VFNBayQpxaE9ntgA2qgoFJU9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:9ecBaKx8wUYyC8iQA4YqcWCZXsY	true	sufficient binding region:61-382	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IWV1-3	uniprotkb:A0A0S2Z442	intact:EBI-12327415|ensembl:ENSP00000356186	intact:EBI-16435864	psi-mi:q8iwv1-3(display_long)|uniprotkb:LAX1(gene name)|psi-mi:LAX1(display_short)|uniprotkb:LAX(gene name synonym)|uniprotkb:Linker for activation of X cells(gene name synonym)|uniprotkb:Membrane-associated adapter protein LAX(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470973	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10232942(isoform-parent)|ensembl:ENSG00000122188(gene)|ensembl:ENST00000367217(transcript)|uniprotkb:Q8IWV1-3(isoform-parent)|entrezgene/locuslink:54900(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16431471(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fIN9VFNBayQpxaE9ntgA2qgoFJU9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:tcH28S8R7Ptj9D9vKthA5Fmxs1s	true	sufficient binding region:61-382	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IWV1-3	uniprotkb:A0A0S2Z3Y6	intact:EBI-12327415|ensembl:ENSP00000356186	intact:EBI-16435852	psi-mi:q8iwv1-3(display_long)|uniprotkb:LAX1(gene name)|psi-mi:LAX1(display_short)|uniprotkb:LAX(gene name synonym)|uniprotkb:Linker for activation of X cells(gene name synonym)|uniprotkb:Membrane-associated adapter protein LAX(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470954	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10232942(isoform-parent)|ensembl:ENSG00000122188(gene)|ensembl:ENST00000367217(transcript)|uniprotkb:Q8IWV1-3(isoform-parent)|entrezgene/locuslink:54900(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16431471(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fIN9VFNBayQpxaE9ntgA2qgoFJU9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:uZ7mhNZJ7A83Wa2NH/CFzgrmP9I	true	sufficient binding region:61-382	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q01081-2	uniprotkb:A0A0S2Z3Z2	intact:EBI-10176676|ensembl:ENSP00000369629	intact:EBI-16470607	psi-mi:q01081-2(display_long)|uniprotkb:U2 auxiliary factor 35 kDa subunit(gene name synonym)|uniprotkb:U2 small nuclear RNA auxiliary factor 1(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor small subunit(gene name synonym)|uniprotkb:U2AF35(gene name synonym)|uniprotkb:U2AFBP(gene name synonym)|uniprotkb:FP793(orf name)|uniprotkb:U2AF35b(isoform synonym)|uniprotkb:U2AF1(gene name)|psi-mi:U2AF1(display_short)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470935	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160201(gene)|ensembl:ENST00000380276(transcript)|intact:EBI-632461(isoform-parent)|uniprotkb:Q01081-2(isoform-parent)|entrezgene/locuslink:7307(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16431062(see-also)	isoform-comment:Interacts with U2AF2 and stimulates U2AF splicing activity in vitro. Less efficient than isoform 1. Contains a N6-methyllysine at position 39.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:I2H9SB2+JgQhbwqaM8J+IE55xNg9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:WQ6UrZX4pCLZ6NDfN6Wy0gdFkZw	true	sufficient binding region:74-240	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q01081-2	uniprotkb:A0A0S2Z442	intact:EBI-10176676|ensembl:ENSP00000369629	intact:EBI-16435864	psi-mi:q01081-2(display_long)|uniprotkb:U2 auxiliary factor 35 kDa subunit(gene name synonym)|uniprotkb:U2 small nuclear RNA auxiliary factor 1(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor small subunit(gene name synonym)|uniprotkb:U2AF35(gene name synonym)|uniprotkb:U2AFBP(gene name synonym)|uniprotkb:FP793(orf name)|uniprotkb:U2AF35b(isoform synonym)|uniprotkb:U2AF1(gene name)|psi-mi:U2AF1(display_short)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470916	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160201(gene)|ensembl:ENST00000380276(transcript)|intact:EBI-632461(isoform-parent)|uniprotkb:Q01081-2(isoform-parent)|entrezgene/locuslink:7307(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16431062(see-also)	isoform-comment:Interacts with U2AF2 and stimulates U2AF splicing activity in vitro. Less efficient than isoform 1. Contains a N6-methyllysine at position 39.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:I2H9SB2+JgQhbwqaM8J+IE55xNg9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:/+yoHs1uVYi535kxEHc07BQnGAg	true	sufficient binding region:74-240	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q01081-2	uniprotkb:A0A0S2Z3Y6	intact:EBI-10176676|ensembl:ENSP00000369629	intact:EBI-16435852	psi-mi:q01081-2(display_long)|uniprotkb:U2 auxiliary factor 35 kDa subunit(gene name synonym)|uniprotkb:U2 small nuclear RNA auxiliary factor 1(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor small subunit(gene name synonym)|uniprotkb:U2AF35(gene name synonym)|uniprotkb:U2AFBP(gene name synonym)|uniprotkb:FP793(orf name)|uniprotkb:U2AF35b(isoform synonym)|uniprotkb:U2AF1(gene name)|psi-mi:U2AF1(display_short)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470897	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160201(gene)|ensembl:ENST00000380276(transcript)|intact:EBI-632461(isoform-parent)|uniprotkb:Q01081-2(isoform-parent)|entrezgene/locuslink:7307(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16431062(see-also)	isoform-comment:Interacts with U2AF2 and stimulates U2AF splicing activity in vitro. Less efficient than isoform 1. Contains a N6-methyllysine at position 39.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:I2H9SB2+JgQhbwqaM8J+IE55xNg9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:RuBM0BsVo6w8+UpQ5FFd+yDPXoo	true	sufficient binding region:74-240	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:A0A0S2Z3Z2	-	intact:EBI-16470607	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470881	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430640(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:qPyYNf3AW/o45LnJgoaqQtGMh/c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:A0A0S2Z442	-	intact:EBI-16435864	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470865	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430640(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:7KfI/IuxpOVxNsQnM+rFT+OqMFY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:A0A0S2Z3Y6	-	intact:EBI-16435852	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470849	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430640(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:0cd2qAiRvZB5gz4DYRNYLlVpPdQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2K1	uniprotkb:A0A0S2Z3Z2	intact:EBI-2682961|uniprotkb:Q86SW8|uniprotkb:A8K6S8|ensembl:ENSP00000451000|ensembl:ENSP00000506911	intact:EBI-16470607	psi-mi:zbtb1_human(display_long)|uniprotkb:KIAA0997(gene name synonym)|uniprotkb:ZBTB1(gene name)|psi-mi:ZBTB1(display_short)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470833	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011534868.1|refseq:XP_011534870.1|refseq:XP_005267467.1|refseq:NP_001116801.1|refseq:NP_055765.2|refseq:XP_016876583.1|refseq:XP_016876584.1|ensembl:ENSG00000126804(gene)|ensembl:ENST00000554015(transcript)|ensembl:ENST00000683701(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002711"(positive regulation of T cell mediated immunity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048538"(thymus development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000176"(positive regulation of pro-T cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:22890(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430450(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:63ZwzhNK0fJBMGUMPfeRJnGqrcE9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:iuDRKMAIvngxSYEmJd9FucPNML4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2K1	uniprotkb:A0A0S2Z442	intact:EBI-2682961|uniprotkb:Q86SW8|uniprotkb:A8K6S8|ensembl:ENSP00000451000|ensembl:ENSP00000506911	intact:EBI-16435864	psi-mi:zbtb1_human(display_long)|uniprotkb:KIAA0997(gene name synonym)|uniprotkb:ZBTB1(gene name)|psi-mi:ZBTB1(display_short)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470817	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011534868.1|refseq:XP_011534870.1|refseq:XP_005267467.1|refseq:NP_001116801.1|refseq:NP_055765.2|refseq:XP_016876583.1|refseq:XP_016876584.1|ensembl:ENSG00000126804(gene)|ensembl:ENST00000554015(transcript)|ensembl:ENST00000683701(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002711"(positive regulation of T cell mediated immunity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048538"(thymus development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000176"(positive regulation of pro-T cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:22890(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430450(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:63ZwzhNK0fJBMGUMPfeRJnGqrcE9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:2R8mLyLilSQ8PzxNivVTUxy1Jcs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2K1	uniprotkb:A0A0S2Z3Y6	intact:EBI-2682961|uniprotkb:Q86SW8|uniprotkb:A8K6S8|ensembl:ENSP00000451000|ensembl:ENSP00000506911	intact:EBI-16435852	psi-mi:zbtb1_human(display_long)|uniprotkb:KIAA0997(gene name synonym)|uniprotkb:ZBTB1(gene name)|psi-mi:ZBTB1(display_short)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470801	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011534868.1|refseq:XP_011534870.1|refseq:XP_005267467.1|refseq:NP_001116801.1|refseq:NP_055765.2|refseq:XP_016876583.1|refseq:XP_016876584.1|ensembl:ENSG00000126804(gene)|ensembl:ENST00000554015(transcript)|ensembl:ENST00000683701(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002711"(positive regulation of T cell mediated immunity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048538"(thymus development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000176"(positive regulation of pro-T cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:22890(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430450(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:63ZwzhNK0fJBMGUMPfeRJnGqrcE9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:N8UsnHnLD2V5Yvg3pKpJxC/YKqA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WVE0	uniprotkb:A0A0S2Z3Z2	intact:EBI-16430415|ensembl:ENSP00000372202|ensembl:ENSP00000372206|uniprotkb:B5G4V1	intact:EBI-16470607	psi-mi:efmt1_human(display_long)|uniprotkb:"N(6)-adenine-specific DNA methyltransferase 2"(gene name synonym)|uniprotkb:Protein-lysine N-methyltransferase N6AMT2(gene name synonym)|uniprotkb:EEF1AKMT1(gene name)|psi-mi:EEF1AKMT1(display_short)|uniprotkb:N6AMT2(gene name synonym)|uniprotkb:eEF1A-KMT(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470785	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150456(gene)|ensembl:ENST00000382754(transcript)|ensembl:ENST00000382758(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018022"(peptidyl-lysine methylation)|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR019369|interpro:IPR029063|interpro:IPR041370|reactome:R-HSA-8876725|refseq:NP_001305868.1|refseq:NP_777588.1|refseq:XP_016875921.1|entrezgene/locuslink:221143(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430440(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qKNqMbQPejzDNq5IswwsVDIUopY9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:ShScts8C1x7m12Qnrh19n2ggep4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WVE0	uniprotkb:A0A0S2Z442	intact:EBI-16430415|ensembl:ENSP00000372202|ensembl:ENSP00000372206|uniprotkb:B5G4V1	intact:EBI-16435864	psi-mi:efmt1_human(display_long)|uniprotkb:"N(6)-adenine-specific DNA methyltransferase 2"(gene name synonym)|uniprotkb:Protein-lysine N-methyltransferase N6AMT2(gene name synonym)|uniprotkb:EEF1AKMT1(gene name)|psi-mi:EEF1AKMT1(display_short)|uniprotkb:N6AMT2(gene name synonym)|uniprotkb:eEF1A-KMT(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16470769	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150456(gene)|ensembl:ENST00000382754(transcript)|ensembl:ENST00000382758(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018022"(peptidyl-lysine methylation)|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR019369|interpro:IPR029063|interpro:IPR041370|reactome:R-HSA-8876725|refseq:NP_001305868.1|refseq:NP_777588.1|refseq:XP_016875921.1|entrezgene/locuslink:221143(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16430440(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qKNqMbQPejzDNq5IswwsVDIUopY9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:vbODVokgUFMGiO+NXwcesmVGLoE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15156-2	uniprotkb:A0A0S2Z3Z2	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-16470607	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471440	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438334(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:e+8ppS7I8y+QjONDJF0qi6zD+yI	true	sufficient binding region:35-573	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H000	uniprotkb:A0A0S2Z442	intact:EBI-2341005|uniprotkb:A6NIA2|uniprotkb:Q9BUY2|uniprotkb:B3KRC5|uniprotkb:Q96BD4|uniprotkb:Q8N391|uniprotkb:Q9NRY1|uniprotkb:B4DPR4|intact:EBI-11126681|ensembl:ENSP00000170447|ensembl:ENSP00000502893	intact:EBI-16435864	psi-mi:mkrn2_human(display_long)|uniprotkb:MKRN2(gene name)|psi-mi:MKRN2(display_short)|uniprotkb:RNF62(gene name synonym)|uniprotkb:RING finger protein 62(gene name synonym)|uniprotkb:HSPC070(orf name)|uniprotkb:RING-type E3 ubiquitin transferase makorin-2(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471048	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054879.3|refseq:NP_001258636.1|ensembl:ENSG00000075975(gene)|ensembl:ENST00000170447(transcript)|ensembl:ENST00000677816(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026293|interpro:IPR036855|interpro:IPR041367|mint:Q9H000|entrezgene/locuslink:23609(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16432997(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZI7Jr4Fd52sQnfeNXXcZ0NscyD89606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:06FbNpECo08K4ooOSd9T7gkz45s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H000	uniprotkb:A0A0S2Z3Z2	intact:EBI-2341005|uniprotkb:A6NIA2|uniprotkb:Q9BUY2|uniprotkb:B3KRC5|uniprotkb:Q96BD4|uniprotkb:Q8N391|uniprotkb:Q9NRY1|uniprotkb:B4DPR4|intact:EBI-11126681|ensembl:ENSP00000170447|ensembl:ENSP00000502893	intact:EBI-16470607	psi-mi:mkrn2_human(display_long)|uniprotkb:MKRN2(gene name)|psi-mi:MKRN2(display_short)|uniprotkb:RNF62(gene name synonym)|uniprotkb:RING finger protein 62(gene name synonym)|uniprotkb:HSPC070(orf name)|uniprotkb:RING-type E3 ubiquitin transferase makorin-2(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471064	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054879.3|refseq:NP_001258636.1|ensembl:ENSG00000075975(gene)|ensembl:ENST00000170447(transcript)|ensembl:ENST00000677816(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026293|interpro:IPR036855|interpro:IPR041367|mint:Q9H000|entrezgene/locuslink:23609(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16432997(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZI7Jr4Fd52sQnfeNXXcZ0NscyD89606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:aEw8vlMRdLtPsdTUtL2KCsyBCzY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P04637	uniprotkb:A0A0S2Z3Y6	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5	intact:EBI-16435852	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471080	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|entrezgene/locuslink:7157(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16433901(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:Liqj0Ux345wGV+oUgnf+BiIWHnk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P04637	uniprotkb:A0A0S2Z442	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5	intact:EBI-16435864	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471096	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|entrezgene/locuslink:7157(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16433901(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:7tKVcq/DsQho2jq5cVGNSsRdNmQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P04637	uniprotkb:A0A0S2Z3Z2	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5	intact:EBI-16470607	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471112	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|entrezgene/locuslink:7157(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16433901(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:RHTJT2pyAVS5RjL1jkpF5wDkHzo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y6B2	uniprotkb:A0A0S2Z3Y6	intact:EBI-1049975|uniprotkb:Q8N7I4|uniprotkb:Q9BZT9|uniprotkb:B2RD11|ensembl:ENSP00000431162	intact:EBI-16435852	psi-mi:eid1_human(display_long)|uniprotkb:EID1(gene name)|psi-mi:EID1(display_short)|uniprotkb:C15orf3(gene name synonym)|uniprotkb:CRI1(gene name synonym)|uniprotkb:RBP21(gene name synonym)|uniprotkb:PNAS-22(orf name)|uniprotkb:PTD014(orf name)|uniprotkb:E1A-like inhibitor of differentiation 1(gene name synonym)|uniprotkb:CREBBP/EP300 inhibitory protein 1(gene name synonym)|uniprotkb:21 kDa pRb-associated protein(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471128	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055150.1|ensembl:ENSG00000255302(gene)|ensembl:ENST00000530028(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0035034"(histone acetyltransferase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR033255|interpro:IPR033258|mint:Q9Y6B2|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|entrezgene/locuslink:23741(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16435244(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VPSCn0cgSMX+Pl+QwutWWqZseLQ9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:peJopJ5DCJxPIP9eoi34XYmyL/w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y6B2	uniprotkb:A0A0S2Z442	intact:EBI-1049975|uniprotkb:Q8N7I4|uniprotkb:Q9BZT9|uniprotkb:B2RD11|ensembl:ENSP00000431162	intact:EBI-16435864	psi-mi:eid1_human(display_long)|uniprotkb:EID1(gene name)|psi-mi:EID1(display_short)|uniprotkb:C15orf3(gene name synonym)|uniprotkb:CRI1(gene name synonym)|uniprotkb:RBP21(gene name synonym)|uniprotkb:PNAS-22(orf name)|uniprotkb:PTD014(orf name)|uniprotkb:E1A-like inhibitor of differentiation 1(gene name synonym)|uniprotkb:CREBBP/EP300 inhibitory protein 1(gene name synonym)|uniprotkb:21 kDa pRb-associated protein(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471144	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055150.1|ensembl:ENSG00000255302(gene)|ensembl:ENST00000530028(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0035034"(histone acetyltransferase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR033255|interpro:IPR033258|mint:Q9Y6B2|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|entrezgene/locuslink:23741(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16435244(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VPSCn0cgSMX+Pl+QwutWWqZseLQ9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:Xc7a+I1GsQMmOQz2E6An9nKuDDM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y6B2	uniprotkb:A0A0S2Z3Z2	intact:EBI-1049975|uniprotkb:Q8N7I4|uniprotkb:Q9BZT9|uniprotkb:B2RD11|ensembl:ENSP00000431162	intact:EBI-16470607	psi-mi:eid1_human(display_long)|uniprotkb:EID1(gene name)|psi-mi:EID1(display_short)|uniprotkb:C15orf3(gene name synonym)|uniprotkb:CRI1(gene name synonym)|uniprotkb:RBP21(gene name synonym)|uniprotkb:PNAS-22(orf name)|uniprotkb:PTD014(orf name)|uniprotkb:E1A-like inhibitor of differentiation 1(gene name synonym)|uniprotkb:CREBBP/EP300 inhibitory protein 1(gene name synonym)|uniprotkb:21 kDa pRb-associated protein(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471160	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055150.1|ensembl:ENSG00000255302(gene)|ensembl:ENST00000530028(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0035034"(histone acetyltransferase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR033255|interpro:IPR033258|mint:Q9Y6B2|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|entrezgene/locuslink:23741(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16435244(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VPSCn0cgSMX+Pl+QwutWWqZseLQ9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:u2NqjNKAFDrBTFN17/yCl0lw8zI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16435328	uniprotkb:A0A0S2Z3Y6	-	intact:EBI-16435852	psi-mi:"ccsb orf id: 52859"(display_short)|psi-mi:EBI-16435328(display_long)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471176	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:64753(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16435350(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FWTUx0ZMr4g1buyVnmwu2LBoxaU9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:B5fg2g+1/hWoGsxKwS5gB6HuaZ0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16435328	uniprotkb:A0A0S2Z442	-	intact:EBI-16435864	psi-mi:"ccsb orf id: 52859"(display_short)|psi-mi:EBI-16435328(display_long)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471192	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:64753(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16435350(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FWTUx0ZMr4g1buyVnmwu2LBoxaU9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:hZ83uoTR5BFLbqnXFrvLuEdU8+Y	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16435328	uniprotkb:A0A0S2Z3Z2	-	intact:EBI-16470607	psi-mi:"ccsb orf id: 52859"(display_short)|psi-mi:EBI-16435328(display_long)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471208	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:64753(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16435350(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FWTUx0ZMr4g1buyVnmwu2LBoxaU9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:eCMl4DnwjTG3V1AhgAmfP8CXyAE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z4N8	intact:EBI-16429055	intact:EBI-10181968|uniprotkb:Q5JPA9|uniprotkb:Q5EBL3|uniprotkb:A0AV13|uniprotkb:B4DUD3|ensembl:ENSP00000332170	-	psi-mi:p4ha3_human(display_long)|uniprotkb:P4HA3(gene name)|psi-mi:P4HA3(display_short)|uniprotkb:Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3(gene name synonym)|uniprotkb:UNQ711/PRO1374(orf name)	psi-mi:"ccsb isoform id: ndn_2"(display_short)|psi-mi:EBI-16429055(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471224	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001275677.1|refseq:NP_878907.1|ensembl:ENSG00000149380(gene)|ensembl:ENST00000331597(transcript)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013547(Prolyl 4-hydroxylase alpha-subunit, N-terminal)|reactome:R-HSA-1650814|entrezgene/locuslink:283208(identity)	entrezgene/locuslink:4692(identity)	intact:EBI-16435854(see-also)|intact:EBI-16435866(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:d1yT0nxg2GYPUs3YnYr4MkodoAU9606	rogid:3/K9NpgPU43gRAJpUk7hAthiupg9606	rigid:xH+hDsYeO4A66g5TJ7EKs7XBREw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z4N8	uniprotkb:A0A0S2Z3Z2	intact:EBI-10181968|uniprotkb:Q5JPA9|uniprotkb:Q5EBL3|uniprotkb:A0AV13|uniprotkb:B4DUD3|ensembl:ENSP00000332170	intact:EBI-16470607	psi-mi:p4ha3_human(display_long)|uniprotkb:P4HA3(gene name)|psi-mi:P4HA3(display_short)|uniprotkb:Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3(gene name synonym)|uniprotkb:UNQ711/PRO1374(orf name)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471241	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001275677.1|refseq:NP_878907.1|ensembl:ENSG00000149380(gene)|ensembl:ENST00000331597(transcript)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013547(Prolyl 4-hydroxylase alpha-subunit, N-terminal)|reactome:R-HSA-1650814|entrezgene/locuslink:283208(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16435854(see-also)|intact:EBI-16435866(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:d1yT0nxg2GYPUs3YnYr4MkodoAU9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:vJmNkxCaD9AB4v1X17w+jg+SX/g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UBB9	uniprotkb:A0A0S2Z3Y6	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0	intact:EBI-16435852	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471258	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16437355(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:AgCCJLUnduhIDoGJIbH8wVF646w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UBB9	uniprotkb:A0A0S2Z442	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0	intact:EBI-16435864	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471274	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16437355(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:FTrbG0AueCyEW+GgOfjieFqqRoc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UBB9	uniprotkb:A0A0S2Z3Z2	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0	intact:EBI-16470607	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471290	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16437355(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:vH7e01MRnuWDuiMOuZXGkHKI6XM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96EV8	uniprotkb:A0A0S2Z3Y6	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	intact:EBI-16435852	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471306	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|entrezgene/locuslink:84062(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438141(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:V9mXo3hkQfeZjGJNjrnB38cMbCc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96EV8	uniprotkb:A0A0S2Z442	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	intact:EBI-16435864	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471322	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|entrezgene/locuslink:84062(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438141(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:m6XiPoCb8/HojF7eoWUgaDD92XM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96EV8	uniprotkb:A0A0S2Z3Z2	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	intact:EBI-16470607	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471338	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|entrezgene/locuslink:84062(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438141(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:PFF6wCF50EPVQZxAGojaafO+lAs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VSY0	uniprotkb:A0A0S2Z3Y6	intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550	intact:EBI-16435852	psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471516	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N|entrezgene/locuslink:80318(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438970(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WPAqDDTftv300tbwXkusTo6tmUo9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:Hr1GjDtiDD55g1ntJJTXFLKboDY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z3Z2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16470607	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471497	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438516(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:qe5/7IhbXMNx7a7SBBoJcYMjIgk	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z442	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16435864	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471478	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438516(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:Q1CiV2ABAf0ewp332ott921uKmw	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z3Y6	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16435852	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471459	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438516(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:6FVyLEzkeikI8kbrexzbhQcam74	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H000	uniprotkb:A0A0S2Z3Y6	intact:EBI-2341005|uniprotkb:A6NIA2|uniprotkb:Q9BUY2|uniprotkb:B3KRC5|uniprotkb:Q96BD4|uniprotkb:Q8N391|uniprotkb:Q9NRY1|uniprotkb:B4DPR4|intact:EBI-11126681|ensembl:ENSP00000170447|ensembl:ENSP00000502893	intact:EBI-16435852	psi-mi:mkrn2_human(display_long)|uniprotkb:MKRN2(gene name)|psi-mi:MKRN2(display_short)|uniprotkb:RNF62(gene name synonym)|uniprotkb:RING finger protein 62(gene name synonym)|uniprotkb:HSPC070(orf name)|uniprotkb:RING-type E3 ubiquitin transferase makorin-2(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471032	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054879.3|refseq:NP_001258636.1|ensembl:ENSG00000075975(gene)|ensembl:ENST00000170447(transcript)|ensembl:ENST00000677816(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026293|interpro:IPR036855|interpro:IPR041367|mint:Q9H000|entrezgene/locuslink:23609(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16432997(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZI7Jr4Fd52sQnfeNXXcZ0NscyD89606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:37DBiLChfJ+UBRTYncymw4krzRw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15156-2	uniprotkb:A0A0S2Z442	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-16435864	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471421	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438334(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:pOaR2PPXAgKBIE16pFKKltITeZg	true	sufficient binding region:35-573	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15156-2	uniprotkb:A0A0S2Z3Y6	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-16435852	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471402	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438334(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:bHrUnHclUs5jhzhQ69Vtxpb1qtM	true	sufficient binding region:35-573	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJW9	uniprotkb:A0A0S2Z442	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	intact:EBI-16435864	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471386	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585|entrezgene/locuslink:29946(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438151(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:VxSXjE4wMZN5XOh9B8/nNncbFAA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJW9	uniprotkb:A0A0S2Z3Y6	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	intact:EBI-16435852	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471370	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585|entrezgene/locuslink:29946(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438151(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:RJ3Z27h+TApsYKOxHcrcRDijYX8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJW9	uniprotkb:Q99608	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471354	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585|entrezgene/locuslink:29946(identity)	refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity)	intact:EBI-16438151(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606	rigid:e8Y5pNDzRW8thoBokvAfadbTYIs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VSY0	uniprotkb:A0A0S2Z442	intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550	intact:EBI-16435864	psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471532	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N|entrezgene/locuslink:80318(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438970(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WPAqDDTftv300tbwXkusTo6tmUo9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:7Yicyok3J9X9AqzSVhv7EWfSVtE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BQQ3	uniprotkb:I6L9F6	intact:EBI-2561458|uniprotkb:Q3SYG7|uniprotkb:Q96H42|uniprotkb:Q8N272|uniprotkb:B3KWC8|ensembl:ENSP00000313869	intact:EBI-10178578|intact:EBI-21999896	psi-mi:gors1_human(display_long)|uniprotkb:GORASP1(gene name)|psi-mi:GORASP1(display_short)|uniprotkb:GOLPH5(gene name synonym)|uniprotkb:GRASP65(gene name synonym)|uniprotkb:Golgi reassembly-stacking protein of 65 kDa(gene name synonym)|uniprotkb:Golgi peripheral membrane protein p65(gene name synonym)|uniprotkb:Golgi phosphoprotein 5(gene name synonym)	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471845	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114105.1|refseq:NP_001265718.1|refseq:NP_001265719.1|ensembl:ENSG00000114745(gene)|ensembl:ENST00000319283(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|rcsb pdb:4REY|rcsb pdb:6G8T|rcsb pdb:6G8W|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|entrezgene/locuslink:64689(identity)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	intact:EBI-16431564(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:gCTXn0H+UPamtVxyvChrMrcQvCA9606	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rigid:DhJtcihLIRS5IOBuY2fwRZB7o/I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96AQ9	uniprotkb:A0A0S2Z3Y6	intact:EBI-741921|ensembl:ENSP00000364814|uniprotkb:Q5T5Q5|uniprotkb:Q8N3X3|uniprotkb:Q8N9P9	intact:EBI-16435852	psi-mi:f131c_human(display_long)|uniprotkb:FAM131C(gene name)|psi-mi:FAM131C(display_short)|uniprotkb:C1orf117(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471564	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185519(gene)|ensembl:ENST00000375662(transcript)|interpro:IPR026782|refseq:NP_872429.2|entrezgene/locuslink:348487(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16439018(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:C85G7ipvJKdcueTSbK+r4W2cboM9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:L63AWUaZ3D8IxO+R2hYNjYxLQUA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96AQ9	uniprotkb:A0A0S2Z442	intact:EBI-741921|ensembl:ENSP00000364814|uniprotkb:Q5T5Q5|uniprotkb:Q8N3X3|uniprotkb:Q8N9P9	intact:EBI-16435864	psi-mi:f131c_human(display_long)|uniprotkb:FAM131C(gene name)|psi-mi:FAM131C(display_short)|uniprotkb:C1orf117(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471580	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185519(gene)|ensembl:ENST00000375662(transcript)|interpro:IPR026782|refseq:NP_872429.2|entrezgene/locuslink:348487(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16439018(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:C85G7ipvJKdcueTSbK+r4W2cboM9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:ps/0XkdLC04mDDNvhYbsHi/3ZjQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96AQ9	uniprotkb:A0A0S2Z3Z2	intact:EBI-741921|ensembl:ENSP00000364814|uniprotkb:Q5T5Q5|uniprotkb:Q8N3X3|uniprotkb:Q8N9P9	intact:EBI-16470607	psi-mi:f131c_human(display_long)|uniprotkb:FAM131C(gene name)|psi-mi:FAM131C(display_short)|uniprotkb:C1orf117(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471596	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185519(gene)|ensembl:ENST00000375662(transcript)|interpro:IPR026782|refseq:NP_872429.2|entrezgene/locuslink:348487(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16439018(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:C85G7ipvJKdcueTSbK+r4W2cboM9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:7+rowNxaDGFRYy/hGzu2lIbCb+g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N344	uniprotkb:A0A0S2Z3Y6	intact:EBI-3504938|uniprotkb:Q9ULM7|intact:EBI-28983418|ensembl:ENSP00000264819	intact:EBI-16435852	psi-mi:mier2_human(display_long)|uniprotkb:MIER2(gene name)|psi-mi:MIER2(display_short)|uniprotkb:KIAA1193(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471612	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060020.1|ensembl:ENSP00000264819|ensembl:ENSG00000105556(gene)|ensembl:ENST00000264819(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR040138|entrezgene/locuslink:54531(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440460(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:hedPKzh11QzR2oqkwIv/Frvg5Yc9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:7z+v8/JSsMFCR4gWeQxZQJbVD6I	true	sufficient binding region:37-545	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N344	uniprotkb:A0A0S2Z442	intact:EBI-3504938|uniprotkb:Q9ULM7|intact:EBI-28983418|ensembl:ENSP00000264819	intact:EBI-16435864	psi-mi:mier2_human(display_long)|uniprotkb:MIER2(gene name)|psi-mi:MIER2(display_short)|uniprotkb:KIAA1193(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471631	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060020.1|ensembl:ENSP00000264819|ensembl:ENSG00000105556(gene)|ensembl:ENST00000264819(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR040138|entrezgene/locuslink:54531(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440460(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:hedPKzh11QzR2oqkwIv/Frvg5Yc9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:cXAj0FINYnsqmRG96OYLX6wuXKo	true	sufficient binding region:37-545	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N344	uniprotkb:A0A0S2Z3Z2	intact:EBI-3504938|uniprotkb:Q9ULM7|intact:EBI-28983418|ensembl:ENSP00000264819	intact:EBI-16470607	psi-mi:mier2_human(display_long)|uniprotkb:MIER2(gene name)|psi-mi:MIER2(display_short)|uniprotkb:KIAA1193(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471650	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060020.1|ensembl:ENSP00000264819|ensembl:ENSG00000105556(gene)|ensembl:ENST00000264819(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR040138|entrezgene/locuslink:54531(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440460(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:hedPKzh11QzR2oqkwIv/Frvg5Yc9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:xfXGKJ58Y01Q83U9AwsLKHeShv4	true	sufficient binding region:37-545	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P51116	uniprotkb:A0A0S2Z3Y6	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	intact:EBI-16435852	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471669	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440932(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:k+VUn7DWy+h7HoOB2ikhqBSsq4Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P51116	uniprotkb:A0A0S2Z442	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	intact:EBI-16435864	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471685	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440932(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:hxoe3gEUnTjYpC3OZX/0lg6JhoY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P51116	uniprotkb:A0A0S2Z3Z2	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	intact:EBI-16470607	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471701	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440932(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:sC7wJQRTHctX69GRJRcDOYPPOTs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z5R6-2	uniprotkb:A0A0S2Z3Y6	intact:EBI-12059807|ensembl:ENSP00000349237	intact:EBI-16435852	psi-mi:q7z5r6-2(display_long)|uniprotkb:APBB1IP(gene name)|psi-mi:APBB1IP(display_short)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:PREL1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 73(gene name synonym)|uniprotkb:RARP1(gene name synonym)|uniprotkb:RIAM(gene name synonym)|uniprotkb:Rap1-GTP-interacting adapter molecule(gene name synonym)|uniprotkb:Retinoic acid-responsive proline-rich protein 1(gene name synonym)	psi-mi:a0a0s2z3y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471717	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000077420(gene)|ensembl:ENST00000356785(transcript)|intact:EBI-2818084(isoform-parent)|uniprotkb:Q7Z5R6-2(isoform-parent)|entrezgene/locuslink:54518(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440942(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yY1eNRBlY6dtad7mPNj7QYlnAqY9606	rogid:eaey9dmevR+Hh3wFZFVagdsh+WU9606	rigid:qdJM4ej6WvLabEGLiLf5aKPQyWk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z5R6-2	uniprotkb:A0A0S2Z442	intact:EBI-12059807|ensembl:ENSP00000349237	intact:EBI-16435864	psi-mi:q7z5r6-2(display_long)|uniprotkb:APBB1IP(gene name)|psi-mi:APBB1IP(display_short)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:PREL1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 73(gene name synonym)|uniprotkb:RARP1(gene name synonym)|uniprotkb:RIAM(gene name synonym)|uniprotkb:Rap1-GTP-interacting adapter molecule(gene name synonym)|uniprotkb:Retinoic acid-responsive proline-rich protein 1(gene name synonym)	psi-mi:a0a0s2z442_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471733	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000077420(gene)|ensembl:ENST00000356785(transcript)|intact:EBI-2818084(isoform-parent)|uniprotkb:Q7Z5R6-2(isoform-parent)|entrezgene/locuslink:54518(identity)	go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440942(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yY1eNRBlY6dtad7mPNj7QYlnAqY9606	rogid:DmTa/VoRh5gsCh1JN8IsJUP5+Qk9606	rigid:+HCzlLeEAOP8NlDPcUGkpjhnz7s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z5R6-2	uniprotkb:A0A0S2Z3Z2	intact:EBI-12059807|ensembl:ENSP00000349237	intact:EBI-16470607	psi-mi:q7z5r6-2(display_long)|uniprotkb:APBB1IP(gene name)|psi-mi:APBB1IP(display_short)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:PREL1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 73(gene name synonym)|uniprotkb:RARP1(gene name synonym)|uniprotkb:RIAM(gene name synonym)|uniprotkb:Rap1-GTP-interacting adapter molecule(gene name synonym)|uniprotkb:Retinoic acid-responsive proline-rich protein 1(gene name synonym)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471749	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000077420(gene)|ensembl:ENST00000356785(transcript)|intact:EBI-2818084(isoform-parent)|uniprotkb:Q7Z5R6-2(isoform-parent)|entrezgene/locuslink:54518(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16440942(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yY1eNRBlY6dtad7mPNj7QYlnAqY9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:gbyyLawO06xWFds+nmZeHgI552g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96HR9-2	uniprotkb:Q9ULP0	intact:EBI-14065960|ensembl:ENSP00000233596	intact:EBI-10323810|uniprotkb:Q96PL9|uniprotkb:Q9GZX0|uniprotkb:H7C600|uniprotkb:B3KNU2|uniprotkb:Q6ZNE7|uniprotkb:Q9GZN3|uniprotkb:Q9GZM1|uniprotkb:Q6ZTI7|uniprotkb:B4DK66|uniprotkb:B4DSW5|ensembl:ENSP00000457659	psi-mi:q96hr9-2(display_long)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)	psi-mi:ndrg4_human(display_long)|uniprotkb:NDRG4(gene name)|psi-mi:NDRG4(display_short)|uniprotkb:BDM1(gene name synonym)|uniprotkb:Brain development-related molecule 1(gene name synonym)|uniprotkb:KIAA1180(gene name synonym)|uniprotkb:N-myc downstream-regulated gene 4 protein(gene name synonym)|uniprotkb:Vascular smooth muscle cell-associated protein 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471765	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96HR9-2(isoform-parent)|intact:EBI-750345(isoform-parent)|ensembl:ENSG00000115255(gene)|ensembl:ENST00000233596(transcript)|entrezgene/locuslink:92840(identity)	refseq:NP_001123959.1|refseq:NP_001229762.1|refseq:NP_001229763.1|refseq:NP_001229764.1|refseq:NP_001229765.1|refseq:NP_065198.1|refseq:NP_075061.1|ensembl:ENSG00000103034(gene)|ensembl:ENST00000570248(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008542"(visual learning)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0048278"(vesicle docking)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060973"(cell migration involved in heart development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2001135"(regulation of endocytic recycling)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030695|mint:Q9ULP0|refseq:XP_016879079.1|entrezgene/locuslink:65009(identity)	intact:EBI-16433207(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:YbC7anRtL9P0N9fSlSCGcFjb6yk9606	rogid:66xDAShV6u8TldB/nbR5ru0h7A49606	rigid:3Srcpa/KoPZf1X73TBB7G128U9I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95197-3	uniprotkb:Q9ULP0	intact:EBI-11525735|ensembl:ENSP00000440874	intact:EBI-10323810|uniprotkb:Q96PL9|uniprotkb:Q9GZX0|uniprotkb:H7C600|uniprotkb:B3KNU2|uniprotkb:Q6ZNE7|uniprotkb:Q9GZN3|uniprotkb:Q9GZM1|uniprotkb:Q6ZTI7|uniprotkb:B4DK66|uniprotkb:B4DSW5|ensembl:ENSP00000457659	psi-mi:o95197-3(display_long)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:A1(isoform synonym)|uniprotkb:B1(isoform synonym)	psi-mi:ndrg4_human(display_long)|uniprotkb:NDRG4(gene name)|psi-mi:NDRG4(display_short)|uniprotkb:BDM1(gene name synonym)|uniprotkb:Brain development-related molecule 1(gene name synonym)|uniprotkb:KIAA1180(gene name synonym)|uniprotkb:N-myc downstream-regulated gene 4 protein(gene name synonym)|uniprotkb:Vascular smooth muscle cell-associated protein 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471781	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133318(gene)|ensembl:ENST00000537981(transcript)|intact:EBI-740467(isoform-parent)|uniprotkb:O95197-3(isoform-parent)|entrezgene/locuslink:10313(identity)	refseq:NP_001123959.1|refseq:NP_001229762.1|refseq:NP_001229763.1|refseq:NP_001229764.1|refseq:NP_001229765.1|refseq:NP_065198.1|refseq:NP_075061.1|ensembl:ENSG00000103034(gene)|ensembl:ENST00000570248(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008542"(visual learning)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0048278"(vesicle docking)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060973"(cell migration involved in heart development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2001135"(regulation of endocytic recycling)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030695|mint:Q9ULP0|refseq:XP_016879079.1|entrezgene/locuslink:65009(identity)	intact:EBI-16434190(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TJnANu85CM52dRZ6s+hYMlUABE9606	rogid:66xDAShV6u8TldB/nbR5ru0h7A49606	rigid:PQvYRWtCv7LBKSjuANpFJemZWaQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:Q9ULP0	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-10323810|uniprotkb:Q96PL9|uniprotkb:Q9GZX0|uniprotkb:H7C600|uniprotkb:B3KNU2|uniprotkb:Q6ZNE7|uniprotkb:Q9GZN3|uniprotkb:Q9GZM1|uniprotkb:Q6ZTI7|uniprotkb:B4DK66|uniprotkb:B4DSW5|ensembl:ENSP00000457659	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:ndrg4_human(display_long)|uniprotkb:NDRG4(gene name)|psi-mi:NDRG4(display_short)|uniprotkb:BDM1(gene name synonym)|uniprotkb:Brain development-related molecule 1(gene name synonym)|uniprotkb:KIAA1180(gene name synonym)|uniprotkb:N-myc downstream-regulated gene 4 protein(gene name synonym)|uniprotkb:Vascular smooth muscle cell-associated protein 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471797	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	refseq:NP_001123959.1|refseq:NP_001229762.1|refseq:NP_001229763.1|refseq:NP_001229764.1|refseq:NP_001229765.1|refseq:NP_065198.1|refseq:NP_075061.1|ensembl:ENSG00000103034(gene)|ensembl:ENST00000570248(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008542"(visual learning)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0048278"(vesicle docking)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060973"(cell migration involved in heart development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2001135"(regulation of endocytic recycling)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030695|mint:Q9ULP0|refseq:XP_016879079.1|entrezgene/locuslink:65009(identity)	intact:EBI-16440024(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:66xDAShV6u8TldB/nbR5ru0h7A49606	rigid:Whl1LFBMHS1e0hKwYCPAPHFExlo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P12757	uniprotkb:I6L9F6	intact:EBI-2902468|uniprotkb:A6NGT1|uniprotkb:O00464|uniprotkb:P12756|uniprotkb:Q07501|uniprotkb:B4DT50|ensembl:ENSP00000259119|ensembl:ENSP00000415243	intact:EBI-10178578|intact:EBI-21999896	psi-mi:skil_human(display_long)|uniprotkb:SKIL(gene name)|psi-mi:SKIL(display_short)|uniprotkb:SNO(gene name synonym)|uniprotkb:Ski-related protein(gene name synonym)|uniprotkb:Ski-related oncogene(gene name synonym)	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471813	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138569.1|refseq:NP_001138570.1|refseq:NP_005405.2|refseq:NP_001234937.1|refseq:XP_005247778.1|ensembl:ENSG00000136603(gene)|ensembl:ENST00000259119(transcript)|ensembl:ENST00000458537(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016605"(PML body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070848"(response to growth factor)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028373|interpro:IPR037000|rcsb pdb:3EQ5|rcsb pdb:5C4V|reactome:R-HSA-2173795|refseq:XP_006713798.1|dip:DIP-42138N|entrezgene/locuslink:6498(identity)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	intact:EBI-16429652(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CktHHQJKOG+DaY5zwy1U+2YeTmw9606	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rigid:60YrFHcyh/IuhDlXROG86Rww+ZI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P17661	uniprotkb:I6L9F6	intact:EBI-1055572|uniprotkb:Q15787|uniprotkb:Q8IZR1|uniprotkb:Q8IZR6|uniprotkb:Q8NES2|uniprotkb:Q8NEU6|uniprotkb:Q8TAC4|uniprotkb:Q8TCX2|uniprotkb:Q8TD99|uniprotkb:Q9UHN5|uniprotkb:Q9UJ80|uniprotkb:Q549R7|uniprotkb:Q549R8|uniprotkb:Q549R9|ensembl:ENSP00000363071	intact:EBI-10178578|intact:EBI-21999896	psi-mi:desm_human(display_long)|uniprotkb:DES(gene name)|psi-mi:DES(display_short)	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471829	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001918.3|ensembl:ENSG00000175084(gene)|ensembl:ENST00000373960(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005916"(fascia adherens)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0014704"(intercalated disc)|go:"GO:0030018"(Z disc)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|mint:P17661|reactome:R-HSA-390522|entrezgene/locuslink:1674(identity)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	intact:EBI-16430919(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:htjPzLKLLbRXxfKz9NUgMYMuIaY9606	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rigid:U3N9F/Nm/jKEf3xoRz7ivTa+OA4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VSY0	uniprotkb:A0A0S2Z3Z2	intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550	intact:EBI-16470607	psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short)	psi-mi:a0a0s2z3z2_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471548	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N|entrezgene/locuslink:80318(identity)	interpro:IPR041899|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|entrezgene/locuslink:4692(identity)	intact:EBI-16438970(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WPAqDDTftv300tbwXkusTo6tmUo9606	rogid:tdC5Yz4OKJZ+hnYBognHHMlFpzo9606	rigid:FM0lsi06TLZ9lpAj6yZ0mnKyB14	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P63098	uniprotkb:Q08209	intact:EBI-915984|uniprotkb:B5MDU4|uniprotkb:P06705|uniprotkb:P15117|uniprotkb:Q08044|uniprotkb:Q53SL0|uniprotkb:B2RC10|ensembl:ENSP00000234310	intact:EBI-352922|uniprotkb:Q8TAW9|uniprotkb:A8K3B7|uniprotkb:B5BUA2|uniprotkb:A1A441|uniprotkb:A8W6Z7|ensembl:ENSP00000378323|uniprotkb:A8W6Z8	psi-mi:canb1_human(display_long)|uniprotkb:PPP3R1(gene name)|psi-mi:PPP3R1(display_short)|uniprotkb:CNA2(gene name synonym)|uniprotkb:CNB(gene name synonym)|uniprotkb:Protein phosphatase 2B regulatory subunit 1(gene name synonym)|uniprotkb:Protein phosphatase 3 regulatory subunit B alpha isoform 1(gene name synonym)	psi-mi:pp2ba_human(display_long)|uniprotkb:PPP3CA(gene name)|psi-mi:PPP3CA(display_short)|uniprotkb:CALNA(gene name synonym)|uniprotkb:CNA(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit alpha isoform(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472290	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000936.1|dip:DIP-6096N|ensembl:ENSG00000221823(gene)|ensembl:ENST00000234310(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0004723"(calcium-dependent protein serine/threonine phosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007507"(heart development)|go:"GO:0008597"(calcium-dependent protein serine/threonine phosphatase regulator activity)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0042383"(sarcolemma)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015757(Calcineurin B protein)|interpro:IPR018247|mint:P63098|rcsb pdb:1AUI|rcsb pdb:1M63|rcsb pdb:1MF8|rcsb pdb:2P6B|rcsb pdb:3LL8|rcsb pdb:4F0Z|rcsb pdb:4OR9|rcsb pdb:4ORA|rcsb pdb:4ORC|rcsb pdb:5SVE|rcsb pdb:6NUC|rcsb pdb:6NUF|rcsb pdb:6NUU|reactome:R-HSA-111447|reactome:R-HSA-180024|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-5607763|entrezgene/locuslink:5534(identity)	go:"GO:1905205"(positive regulation of connective tissue replacement)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|mint:Q08209|rcsb pdb:1AUI|rcsb pdb:1M63|rcsb pdb:1MF8|rcsb pdb:2JOG|rcsb pdb:2JZI|rcsb pdb:2P6B|rcsb pdb:2R28|rcsb pdb:2W73|rcsb pdb:3LL8|rcsb pdb:4F0Z|rcsb pdb:4Q5U|rcsb pdb:5C1V|rcsb pdb:5SVE|rcsb pdb:6NUC|rcsb pdb:6NUF|rcsb pdb:6NUU|rcsb pdb:6UUQ|reactome:R-HSA-180024|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-5607763|reactome:R-HSA-2025928|refseq:NP_000935.1|refseq:NP_001124163.1|refseq:NP_001124164.1|go:"GO:0043197"(dendritic spine)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903244"(positive regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000138814(gene)|ensembl:ENST00000394854(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0036057"(slit diaphragm)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042383"(sarcolemma)|dip:DIP-6095N|entrezgene/locuslink:5530(identity)	intact:EBI-16439789(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RqM4Q9x8EiLx7CyoF2Rvjl5RddM9606	rogid:kYtl+Yk39rbcDp5vIjH8WLsZysU9606	rigid:TBMBRaQOIBs3sHBRkxKucLjJI8U	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6P597-2	uniprotkb:I6L9F6	intact:EBI-11033402|ensembl:ENSP00000466067	intact:EBI-10178578|intact:EBI-21999896	psi-mi:q6p597-2(display_long)|uniprotkb:KLC3(gene name)|psi-mi:KLC3(display_short)|uniprotkb:KLC2(gene name synonym)|uniprotkb:KLC2-like(gene name synonym)|uniprotkb:KLC2L(gene name synonym)|uniprotkb:kinesin light chain 2(gene name synonym)	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471874	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1643885(isoform-parent)|uniprotkb:Q6P597-2(isoform-parent)|ensembl:ENSG00000104892(gene)|ensembl:ENST00000585434(transcript)|entrezgene/locuslink:147700(identity)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	intact:EBI-16431586(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:zVaRhvX9+4Aehqcmowox73QTJIM9606	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rigid:A6QyR1rBN8hJrbSre9es50TL0H8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96HD9	intact:EBI-16472255	intact:EBI-3916242|ensembl:ENSP00000255082	-	psi-mi:acy3_human(display_long)|uniprotkb:ACY3(gene name)|psi-mi:ACY3(display_short)|uniprotkb:Aspartoacylase-2(gene name synonym)|uniprotkb:ASPA2(gene name synonym)|uniprotkb:Acylase III(gene name synonym)|uniprotkb:Aminoacylase-3(gene name synonym)|uniprotkb:Hepatitis C virus core-binding protein 1(gene name synonym)	psi-mi:"ccsb isoform id: pmm2_2"(display_short)|psi-mi:EBI-16472255(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472258	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_542389.1|ensembl:ENSG00000132744(gene)|ensembl:ENST00000255082(transcript)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|mint:Q96HD9|reactome:R-HSA-5423646|go:"GO:0005829"(cytosol)|entrezgene/locuslink:91703(identity)	entrezgene/locuslink:5373(identity)	intact:EBI-16433187(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Zjs7m7GTDeoVuV1/ggtGOu1LRhM9606	rogid:0YDh3c3stuQYjWrXuET8c1cw22E9606	rigid:u/mZ+BNuVWxcL4y4dvFNAZolHFY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P60201	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-8653150|uniprotkb:P06905|uniprotkb:P04400|intact:MINT-8164000|uniprotkb:Q502Y1|uniprotkb:Q6FHZ6|ensembl:ENSP00000481006|ensembl:ENSP00000484450	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:mypr_human(display_long)|uniprotkb:PLP1(gene name)|psi-mi:PLP1(display_short)|uniprotkb:Lipophilin(gene name synonym)|uniprotkb:PLP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472239	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_001291933.1|refseq:NP_955772.1|refseq:NP_000524.3|refseq:NP_001122306.1|ensembl:ENSG00000123560(gene)|ensembl:ENST00000612423(transcript)|ensembl:ENST00000621218(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008366"(axon ensheathment)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014002"(astrocyte development)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0034683"(integrin alphav-beta3 complex)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0061564"(axon development)|go:"GO:0098990"(AMPA selective glutamate receptor signaling pathway)|go:"GO:1904427"(positive regulation of calcium ion transmembrane transport)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|mint:P60201|rcsb pdb:2XPG|entrezgene/locuslink:5354(identity)	intact:EBI-16438810(see-also)	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	comment:mint	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:b7pt7FJVt10Iu1tTMeiVYEu5r/k9606	rigid:iwOcglLOmsndgtDROLLCVL52mmo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P60201	uniprotkb:Q16849-3	intact:EBI-8653150|uniprotkb:P06905|uniprotkb:P04400|intact:MINT-8164000|uniprotkb:Q502Y1|uniprotkb:Q6FHZ6|ensembl:ENSP00000481006|ensembl:ENSP00000484450	intact:EBI-10200782|ensembl:ENSP00000392598	psi-mi:mypr_human(display_long)|uniprotkb:PLP1(gene name)|psi-mi:PLP1(display_short)|uniprotkb:Lipophilin(gene name synonym)|uniprotkb:PLP(gene name synonym)	psi-mi:q16849-3(display_long)|uniprotkb:ICA3(gene name synonym)|uniprotkb:ICA512(gene name synonym)|uniprotkb:Islet cell antigen 512(gene name synonym)|uniprotkb:Islet cell autoantigen 3(gene name synonym)|uniprotkb:PTP IA-2(gene name synonym)|uniprotkb:PTPRN(gene name)|psi-mi:PTPRN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472220	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291933.1|refseq:NP_955772.1|refseq:NP_000524.3|refseq:NP_001122306.1|ensembl:ENSG00000123560(gene)|ensembl:ENST00000612423(transcript)|ensembl:ENST00000621218(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008366"(axon ensheathment)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014002"(astrocyte development)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0034683"(integrin alphav-beta3 complex)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0061564"(axon development)|go:"GO:0098990"(AMPA selective glutamate receptor signaling pathway)|go:"GO:1904427"(positive regulation of calcium ion transmembrane transport)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|mint:P60201|rcsb pdb:2XPG|entrezgene/locuslink:5354(identity)	intact:EBI-728153(isoform-parent)|ensembl:ENSG00000054356(gene)|ensembl:ENST00000423636(transcript)|uniprotkb:Q16849-3(isoform-parent)|entrezgene/locuslink:5798(identity)	intact:EBI-16434953(see-also)	comment:mint	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:b7pt7FJVt10Iu1tTMeiVYEu5r/k9606	rogid:i147CXtVMOlCBDl3Wto2zw6GSPU9606	rigid:5se/Z0tdMjX2p6qCjvM39i7JpqI	true	-	sufficient binding region:299-889	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9P2K3-2	uniprotkb:Q96EK2	intact:EBI-1504830|ensembl:ENSP00000355973	intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0	psi-mi:q9p2k3-2(display_long)|uniprotkb:RCOR3(gene name)|psi-mi:RCOR3(display_short)|uniprotkb:KIAA1343(gene name synonym)	psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472203	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000117625(gene)|ensembl:ENST00000367006(transcript)|intact:EBI-743428(isoform-parent)|uniprotkb:Q9P2K3-2(isoform-parent)|entrezgene/locuslink:55758(identity)	ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1|entrezgene/locuslink:112885(identity)	intact:EBI-16440174(see-also)|intact:EBI-16440184(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RU9KkQB+JnxYVfG5IlAeNKnVFjw9606	rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606	rigid:tmtF2t8tQ5EsOCjtO44Y/bx6pJY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:Q96EK2	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472186	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1|entrezgene/locuslink:112885(identity)	intact:EBI-16437800(see-also)|intact:EBI-16437810(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606	rigid:DOVGuKuwNdi0gREbZoVxrSYJppo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:Q96EK2-3	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-16437793|ensembl:ENSP00000487086	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:q96ek2-3(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym)|uniprotkb:3(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472170	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	ensembl:ENST00000629843(transcript)|ensembl:ENSG00000056487(gene)|intact:EBI-16472119(isoform-parent)|uniprotkb:Q96EK2-3(isoform-parent)|entrezgene/locuslink:112885(identity)	intact:EBI-16434037(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:9SKSd1jo6PtvaF/ASqHgPFhu8aA9606	rigid:j1oPjYc7jmKeaQKidkQQlq/2GZI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:Q96EK2	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472154	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1|entrezgene/locuslink:112885(identity)	intact:EBI-16434037(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606	rigid:Uos2STIXhb3b4aMIQYQls3Uv5ns	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NWT1	uniprotkb:Q04864-2	intact:EBI-7641942|ensembl:ENSP00000368887|ensembl:ENSP00000496482|uniprotkb:Q5T4J2|uniprotkb:Q96T87|intact:MINT-3057412|uniprotkb:Q96QJ8	intact:EBI-10829018|ensembl:ENSP00000377989	psi-mi:pk1ip_human(display_long)|uniprotkb:PAK1IP1(gene name)|psi-mi:PAK1IP1(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:WDR84(gene name synonym)|uniprotkb:PAK1-interacting protein 1(gene name synonym)|uniprotkb:PAK/PLC-interacting protein 1(gene name synonym)|uniprotkb:WD repeat-containing protein 84(gene name synonym)	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000111845(gene)|ensembl:ENSG00000285226(gene)|ensembl:ENST00000379568(transcript)|ensembl:ENST00000644756(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NWT1|refseq:NP_060376.2|entrezgene/locuslink:55003(identity)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	intact:EBI-16435768(see-also)	comment:mint|function:Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nAGXksSPZ1aDBtcWOP59JX/lQGA9606	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rigid:+iNGwo1wK5QcKqQ4zUPD6I63vj4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NWT1	uniprotkb:P31323	intact:EBI-7641942|ensembl:ENSP00000368887|ensembl:ENSP00000496482|uniprotkb:Q5T4J2|uniprotkb:Q96T87|intact:MINT-3057412|uniprotkb:Q96QJ8	intact:EBI-2930670|ensembl:ENSP00000265717|ensembl:ENSP00000491687|uniprotkb:A4D0R9	psi-mi:pk1ip_human(display_long)|uniprotkb:PAK1IP1(gene name)|psi-mi:PAK1IP1(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:WDR84(gene name synonym)|uniprotkb:PAK1-interacting protein 1(gene name synonym)|uniprotkb:PAK/PLC-interacting protein 1(gene name synonym)|uniprotkb:WD repeat-containing protein 84(gene name synonym)	psi-mi:kap3_human(display_long)|uniprotkb:PRKAR2B(gene name)|psi-mi:PRKAR2B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472087	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000111845(gene)|ensembl:ENSG00000285226(gene)|ensembl:ENST00000379568(transcript)|ensembl:ENST00000644756(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NWT1|refseq:NP_060376.2|entrezgene/locuslink:55003(identity)	ensembl:ENSG00000005249(gene)|ensembl:ENSG00000284096(gene)|ensembl:ENST00000265717(transcript)|ensembl:ENST00000639737(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0007612"(learning)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P31323|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|refseq:NP_002727.2|dip:DIP-554N|entrezgene/locuslink:5577(identity)	intact:EBI-16431733(see-also)	comment:mint|function:Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nAGXksSPZ1aDBtcWOP59JX/lQGA9606	rogid:P643dCCYtpt/EkR7tmZrbo97FLE9606	rigid:h4XXAW4XX4GP4DPWk7kg7yghHRA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q86SE8-2	uniprotkb:P06748	intact:EBI-12193061|ensembl:ENSP00000370941|ensembl:ENSP00000481018	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755	psi-mi:q86se8-2(display_long)|uniprotkb:NPM2(gene name)|psi-mi:NPM2(display_short)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472071	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6658150(isoform-parent)|ensembl:ENSG00000158806(gene)|ensembl:ENST00000381530(transcript)|ensembl:ENST00000615914(transcript)|uniprotkb:Q86SE8-2(isoform-parent)|entrezgene/locuslink:10361(identity)	refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|entrezgene/locuslink:4869(identity)	intact:EBI-16431830(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/shy9sQPj5fdrbQSf7adFExPv509606	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	rigid:Eu7F8xODXGCQodPaIdotgvqU9aU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15942	uniprotkb:P56597	intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7	intact:EBI-740667|ensembl:ENSP00000265191|uniprotkb:B2R5G7	psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:ndk5_human(display_long)|uniprotkb:nm23-H5(gene name synonym)|uniprotkb:Testis-specific nm23 homolog(gene name synonym)|uniprotkb:Inhibitor of p53-induced apoptosis-beta(gene name synonym)|uniprotkb:NME5(gene name)|psi-mi:NME5(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472055	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1|entrezgene/locuslink:7791(identity)	refseq:NP_003542.1|ensembl:ENSG00000112981(gene)|ensembl:ENST00000265191(transcript)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005929"(cilium)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0021591"(ventricular system development)|go:"GO:0036126"(sperm flagellum)|go:"GO:0060271"(cilium assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR007858(Dpy-30)|interpro:IPR012410(Nucleoside-diphosphate kinase-like NDK-H5)|interpro:IPR034907|interpro:IPR036850|entrezgene/locuslink:8382(identity)	intact:EBI-16434589(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606	rogid:flqa+tg4JH0cBA5svsCSdmuGYys9606	rigid:lSGJdFmVd3xO/S/6vPO3jtF/Jvo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P56597	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-740667|ensembl:ENSP00000265191|uniprotkb:B2R5G7	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:ndk5_human(display_long)|uniprotkb:nm23-H5(gene name synonym)|uniprotkb:Testis-specific nm23 homolog(gene name synonym)|uniprotkb:Inhibitor of p53-induced apoptosis-beta(gene name synonym)|uniprotkb:NME5(gene name)|psi-mi:NME5(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472039	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	refseq:NP_003542.1|ensembl:ENSG00000112981(gene)|ensembl:ENST00000265191(transcript)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005929"(cilium)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0021591"(ventricular system development)|go:"GO:0036126"(sperm flagellum)|go:"GO:0060271"(cilium assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR007858(Dpy-30)|interpro:IPR012410(Nucleoside-diphosphate kinase-like NDK-H5)|interpro:IPR034907|interpro:IPR036850|entrezgene/locuslink:8382(identity)	intact:EBI-16430546(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:flqa+tg4JH0cBA5svsCSdmuGYys9606	rigid:GE1IIt+yVfHQh11pD8DxPa0imMc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0-2	uniprotkb:Q9NZ94-2	intact:EBI-10173939|ensembl:ENSP00000257468	intact:EBI-16423037	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472023	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent)|entrezgene/locuslink:54413(identity)	intact:EBI-16431179(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rogid:zJAbB1paiNIkvVmQQT638+rczN49606	rigid:v/e5UXz62BGKyIqA+6CxC44kTjQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P07196	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472004	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|entrezgene/locuslink:4747(identity)	intact:EBI-16440868(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606	rigid:/jMaClIPjc+ha5XXS/pnkXE3rKg	true	-	sufficient binding region:1-377	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P0C7W6	uniprotkb:I6L9F6	intact:EBI-2548868|ensembl:ENSP00000329860	intact:EBI-10178578|intact:EBI-21999896	psi-mi:cc172_human(display_long)|uniprotkb:CCDC172(gene name)|psi-mi:CCDC172(display_short)|uniprotkb:C10orf96(gene name synonym)	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471988	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_940917.1|ensembl:ENSG00000182645(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0097225"(sperm midpiece)|interpro:IPR029618|mint:P0C7W6|ensembl:ENST00000333254(transcript)|refseq:XP_016871695.1|entrezgene/locuslink:374355(identity)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	intact:EBI-16440694(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JAaMYXob1bjFtiCvHmuzgCvq+FU9606	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rigid:bqt5fey0jbY+6v3HCfGp1oRV1NM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16439879	uniprotkb:I6L9F6	-	intact:EBI-10178578|intact:EBI-21999896	psi-mi:"ccsb orf id: 8359"(display_short)|psi-mi:EBI-16439879(display_long)	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471972	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:80125(identity)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	intact:EBI-16439881(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:poddy6+Qr+z8s1U2xyFnXJ05O6Y9606	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rigid:8QaA/MJgLnCNAFv2+GUWm1wL1rQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:P07196	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471953	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|entrezgene/locuslink:4747(identity)	intact:EBI-16439839(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606	rigid:40LNdlMQMqMBRSwO1sTKaSPtIJQ	true	-	sufficient binding region:1-377	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P07196	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471931	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|entrezgene/locuslink:4747(identity)	intact:EBI-16438528(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606	rigid:gVbM/IrSNp1AIb2n/qpYN8tIadc	true	sufficient binding region:383-1002	sufficient binding region:1-377	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IYF3-3	uniprotkb:P07196	intact:EBI-11523345|ensembl:ENSP00000363453	intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471909	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|entrezgene/locuslink:4747(identity)	intact:EBI-16432766(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606	rigid:FVfBArJib5IuVn0U1Lt/RjVHkA8	true	sufficient binding region:9-925	sufficient binding region:1-377	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:I6L9F6	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-10178578|intact:EBI-21999896	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:i6l9f6_human(display_long)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16471890	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR027692|go:"GO:0005883"(neurofilament)|go:"GO:0061564"(axon development)|entrezgene/locuslink:4747(identity)	intact:EBI-16431902(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:iummVkzByLKqPeBNfjI32TYXy1k9606	rigid:v8+T373idqYQsdVrdh3nra4+znk	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P62140	uniprotkb:O60237-2	intact:EBI-352350|uniprotkb:P37140|uniprotkb:Q5U087|uniprotkb:Q6FG45|uniprotkb:D6W565|uniprotkb:B2R5V4|ensembl:ENSP00000296122|ensembl:ENSP00000351298|ensembl:ENSP00000378769	intact:EBI-10700351|ensembl:ENSP00000349206	psi-mi:pp1b_human(display_long)|uniprotkb:PPP1CB(gene name)|psi-mi:PPP1CB(display_short)	psi-mi:o60237-2(display_long)|uniprotkb:PPP1R12B(gene name)|psi-mi:PPP1R12B(display_short)|uniprotkb:MYPT2(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472274	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002700.1|refseq:NP_996759.1|ensembl:ENSG00000213639(gene)|ensembl:ENST00000296122(transcript)|ensembl:ENST00000358506(transcript)|ensembl:ENST00000395366(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62140|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2565942|reactome:R-HSA-400253|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5673000|reactome:R-HSA-9660537|dip:DIP-33220N|entrezgene/locuslink:5500(identity)	ensembl:ENSG00000077157(gene)|ensembl:ENST00000356764(transcript)|intact:EBI-2558026(isoform-parent)|uniprotkb:O60237-2(isoform-parent)|entrezgene/locuslink:4660(identity)	intact:EBI-16434212(see-also)	-	isoform-comment:Produced by alternative splicing of isoform 1. No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VtNJVyimeiEuRDDWtGswTqoSOH89606	rogid:vroZRva3UhIrZLt/UaNvIhLoZWI9606	rigid:uJwnf7n0u3j9E9KKWB24k9OT1Jk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978	uniprotkb:Q96PK6	intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1	intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484	psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472535	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N|entrezgene/locuslink:3190(identity)	ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N|entrezgene/locuslink:10432(identity)	intact:EBI-16438860(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606	rigid:fa6T4f9JDRgzDWRZ/khZMqSSRMo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978-2	uniprotkb:Q96PK6	intact:EBI-7060731|ensembl:ENSP00000365439|ensembl:ENSP00000365458|uniprotkb:Q07244-2|intact:MINT-225449	intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484	psi-mi:p61978-2(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472519	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|ensembl:ENST00000376263(transcript)|ensembl:ENST00000376281(transcript)|intact:EBI-304185(isoform-parent)|uniprotkb:P61978-2(isoform-parent)|entrezgene/locuslink:3190(identity)	ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N|entrezgene/locuslink:10432(identity)	intact:EBI-16434788(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:FX/iS2YfOhD0ntY2oqpOUetACqg9606	rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606	rigid:3KhOScmBqaMU84aGSRt2Vsb7oNQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978-2	uniprotkb:Q96PK6	intact:EBI-7060731|ensembl:ENSP00000365439|ensembl:ENSP00000365458|uniprotkb:Q07244-2|intact:MINT-225449	intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484	psi-mi:p61978-2(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472503	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|ensembl:ENST00000376263(transcript)|ensembl:ENST00000376281(transcript)|intact:EBI-304185(isoform-parent)|uniprotkb:P61978-2(isoform-parent)|entrezgene/locuslink:3190(identity)	ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N|entrezgene/locuslink:10432(identity)	intact:EBI-16434788(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:FX/iS2YfOhD0ntY2oqpOUetACqg9606	rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606	rigid:3KhOScmBqaMU84aGSRt2Vsb7oNQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUI8	uniprotkb:Q96PK6	intact:EBI-2872414|ensembl:ENSP00000318804|uniprotkb:Q2MLY7|uniprotkb:A6NJF3|uniprotkb:B2R8C3|uniprotkb:Q9Y6M8|uniprotkb:Q9UNI3	intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484	psi-mi:crlf3_human(display_long)|uniprotkb:CRLF3(gene name)|psi-mi:CRLF3(display_short)|uniprotkb:CRLM9(gene name synonym)|uniprotkb:CREME9(gene name synonym)|uniprotkb:CYTOR4(gene name synonym)|uniprotkb:P48(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 9(gene name synonym)|uniprotkb:Cytokine receptor-related protein 4(gene name synonym)|uniprotkb:Type I cytokine receptor-like factor p48(gene name synonym)	psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472487	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000176390(gene)|ensembl:ENST00000324238(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:Q8IUI8|refseq:NP_057070.3|entrezgene/locuslink:51379(identity)	ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N|entrezgene/locuslink:10432(identity)	intact:EBI-16430857(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/20	rogid:iUxgX/ff546WqMhszXxotEhEZ3c9606	rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606	rigid:H5kn/JCSrCdjmf1C41W93OtKoyw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUI8	uniprotkb:Q96PK6	intact:EBI-2872414|ensembl:ENSP00000318804|uniprotkb:Q2MLY7|uniprotkb:A6NJF3|uniprotkb:B2R8C3|uniprotkb:Q9Y6M8|uniprotkb:Q9UNI3	intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484	psi-mi:crlf3_human(display_long)|uniprotkb:CRLF3(gene name)|psi-mi:CRLF3(display_short)|uniprotkb:CRLM9(gene name synonym)|uniprotkb:CREME9(gene name synonym)|uniprotkb:CYTOR4(gene name synonym)|uniprotkb:P48(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 9(gene name synonym)|uniprotkb:Cytokine receptor-related protein 4(gene name synonym)|uniprotkb:Type I cytokine receptor-like factor p48(gene name synonym)	psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472468	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000176390(gene)|ensembl:ENST00000324238(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:Q8IUI8|refseq:NP_057070.3|entrezgene/locuslink:51379(identity)	ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N|entrezgene/locuslink:10432(identity)	intact:EBI-16430857(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:iUxgX/ff546WqMhszXxotEhEZ3c9606	rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606	rigid:H5kn/JCSrCdjmf1C41W93OtKoyw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P05783	uniprotkb:Q9H939-2	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487|ensembl:ENSP00000373489	intact:EBI-16472446|ensembl:ENSP00000468622	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:q9h939-2(display_long)|uniprotkb:PSTPIP2(gene name)|psi-mi:PSTPIP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472452	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005912"(adherens junction)|go:"GO:0007049"(cell cycle)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009750"(response to fructose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0072497"(mesenchymal stem cell differentiation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1902488"(cholangiocyte apoptotic process)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR027695|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|ensembl:ENSG00000111057(gene)|ensembl:ENST00000388835(transcript)|ensembl:ENST00000388837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|refseq:NP_000215.1|refseq:NP_954657.1|dip:DIP-633N|entrezgene/locuslink:3875(identity)	ensembl:ENSG00000152229(gene)|ensembl:ENST00000589328(transcript)|intact:EBI-2609610(isoform-parent)|entrezgene/locuslink:9050(identity)	intact:EBI-16437711(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	rogid:RH1ReONZZRaeyckEt4RrJM7+Y6o9606	rigid:Z6T8ysweiEL3Fm5Rve8vetolld0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NTZ6	uniprotkb:P55345-4	intact:EBI-310707|uniprotkb:E1P5R6|uniprotkb:B3KRU2|uniprotkb:O94865|uniprotkb:Q8N3B1|uniprotkb:Q9H196|ensembl:ENSP00000352668|ensembl:ENSP00000363217|ensembl:ENSP00000363228	intact:EBI-16472326|ensembl:ENSP00000411984	psi-mi:rbm12_human(display_long)|uniprotkb:HRIHFB2091(orf name)|uniprotkb:RBM12(gene name)|psi-mi:RBM12(display_short)|uniprotkb:KIAA0765(gene name synonym)|uniprotkb:RNA-binding motif protein 12(gene name synonym)|uniprotkb:SH3/WW domain anchor protein in the nucleus(gene name synonym)	psi-mi:p55345-4(display_long)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472426	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185767.1|refseq:NP_001185769.1|refseq:NP_006038.2|refseq:NP_690051.1|ensembl:ENSG00000244462(gene)|ensembl:ENST00000359646(transcript)|ensembl:ENST00000374104(transcript)|ensembl:ENST00000374114(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034591|interpro:IPR034594|interpro:IPR034854|interpro:IPR034855|interpro:IPR034856|interpro:IPR035979|mint:Q9NTZ6|rcsb pdb:1WEL|rcsb pdb:2CPY|rcsb pdb:2DNN|rcsb pdb:2EK1|rcsb pdb:2EK6|entrezgene/locuslink:10137(identity)	ensembl:ENSG00000160310(gene)|ensembl:ENST00000451211(transcript)|intact:EBI-78458(isoform-parent)|entrezgene/locuslink:3275(identity)	intact:EBI-16437870(see-also)|intact:EBI-16437880(see-also)	-	isoform-comment:Higher expression in breast cancer tissues.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Hcz7OUumWYuRnRNMjwFYUZBquVo9606	rogid:s+e1GGHPoCi3o58rrtF923d2mos9606	rigid:XgfZ/RRHPs7PoKp4qJMnC8ihfRY	true	-	sufficient binding region:1-286	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYN7	uniprotkb:P55345-4	intact:EBI-9089622|uniprotkb:Q5JXM8|uniprotkb:B7ZM09|uniprotkb:B2RXE5|uniprotkb:Q96ST5|uniprotkb:A2RUF4|ensembl:ENSP00000364346	intact:EBI-16472326|ensembl:ENSP00000411984	psi-mi:zn341_human(display_long)|uniprotkb:ZNF341(gene name)|psi-mi:ZNF341(display_short)	psi-mi:p55345-4(display_long)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472407	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269862.1|refseq:NP_001269864.1|refseq:NP_116208.3|ensembl:ENSG00000131061(gene)|ensembl:ENST00000375200(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:84905(identity)	ensembl:ENSG00000160310(gene)|ensembl:ENST00000451211(transcript)|intact:EBI-78458(isoform-parent)|entrezgene/locuslink:3275(identity)	intact:EBI-16436358(see-also)	-	isoform-comment:Higher expression in breast cancer tissues.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dEc17LamYWGrumF7ngc3Ayq4Q5E9606	rogid:s+e1GGHPoCi3o58rrtF923d2mos9606	rigid:oI6V8T9YE+aB+BUPjd/6KuACB4o	true	-	sufficient binding region:1-286	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYN7-2	uniprotkb:P55345-4	intact:EBI-16435478|ensembl:ENSP00000344308	intact:EBI-16472326|ensembl:ENSP00000411984	psi-mi:q9byn7-2(display_long)|uniprotkb:ZNF341(gene name)|psi-mi:ZNF341(display_short)	psi-mi:p55345-4(display_long)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472388	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-9089622(isoform-parent)|uniprotkb:Q9BYN7-2(isoform-parent)|ensembl:ENSG00000131061(gene)|ensembl:ENST00000342427(transcript)|entrezgene/locuslink:84905(identity)	ensembl:ENSG00000160310(gene)|ensembl:ENST00000451211(transcript)|intact:EBI-78458(isoform-parent)|entrezgene/locuslink:3275(identity)	intact:EBI-16435483(see-also)	isoform-comment:Gene prediction based on EST data.	isoform-comment:Higher expression in breast cancer tissues.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7vGJ+B6pyJ7Sog6LMmkaucXK7wI9606	rogid:s+e1GGHPoCi3o58rrtF923d2mos9606	rigid:YWgJMZcF6cB9o7e4GjZbzfphqgk	true	-	sufficient binding region:1-286	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13191	intact:EBI-16429374	intact:EBI-744027|uniprotkb:Q63Z43|uniprotkb:A8K9S7|uniprotkb:Q13192|uniprotkb:Q13193|uniprotkb:Q3LIC0|uniprotkb:Q8IVC5|uniprotkb:B7WNM4|intact:EBI-28969458|ensembl:ENSP00000377598|intact:EBI-8051403|intact:MINT-7907019	-	psi-mi:cblb_human(display_long)|uniprotkb:Signal transduction protein CBL-B(gene name synonym)|uniprotkb:SH3-binding protein CBL-B(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene b(gene name synonym)|uniprotkb:RING finger protein 56(gene name synonym)|uniprotkb:CBLB(gene name)|psi-mi:CBLB(display_short)|uniprotkb:RNF56(gene name synonym)|uniprotkb:Nbla00127(orf name)|uniprotkb:RING-type E3 ubiquitin transferase CBL-B(gene name synonym)	psi-mi:"ccsb isoform id: prmt2_3"(display_short)|psi-mi:EBI-16429374(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472372	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_733762.2|refseq:NP_001308717.1|ensembl:ENSP00000377598|ensembl:ENST00000403724|ensembl:ENSP00000384816|ensembl:ENST00000405772|ensembl:ENSP00000384938|refseq:XP_011511559.1|ensembl:ENSG00000114423(gene)|ensembl:ENST00000394030(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018193"(peptidyl-amino acid modification)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042110"(T cell activation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:Q13191|rcsb pdb:2AK5|rcsb pdb:2BZ8|rcsb pdb:2DO6|rcsb pdb:2J6F|rcsb pdb:2JNH|rcsb pdb:2LDR|rcsb pdb:2OOA|rcsb pdb:2OOB|rcsb pdb:3PFV|rcsb pdb:3VGO|rcsb pdb:3ZNI|reactome:R-HSA-983168|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|dip:DIP-33091N|entrezgene/locuslink:868(identity)	entrezgene/locuslink:3275(identity)	intact:EBI-16432622(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:cJ5eLH0TMyM6OtmS1sM3rhsrsIk9606	rogid:OAAEKxGVtSlipjL4kONluFkiFFg9606	rigid:EtjRioy0w8WnVMUnPX01HgGZl5w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13191	uniprotkb:P55345-4	intact:EBI-744027|uniprotkb:Q63Z43|uniprotkb:A8K9S7|uniprotkb:Q13192|uniprotkb:Q13193|uniprotkb:Q3LIC0|uniprotkb:Q8IVC5|uniprotkb:B7WNM4|intact:EBI-28969458|ensembl:ENSP00000377598|intact:EBI-8051403|intact:MINT-7907019	intact:EBI-16472326|ensembl:ENSP00000411984	psi-mi:cblb_human(display_long)|uniprotkb:Signal transduction protein CBL-B(gene name synonym)|uniprotkb:SH3-binding protein CBL-B(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene b(gene name synonym)|uniprotkb:RING finger protein 56(gene name synonym)|uniprotkb:CBLB(gene name)|psi-mi:CBLB(display_short)|uniprotkb:RNF56(gene name synonym)|uniprotkb:Nbla00127(orf name)|uniprotkb:RING-type E3 ubiquitin transferase CBL-B(gene name synonym)	psi-mi:p55345-4(display_long)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472353	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_733762.2|refseq:NP_001308717.1|ensembl:ENSP00000377598|ensembl:ENST00000403724|ensembl:ENSP00000384816|ensembl:ENST00000405772|ensembl:ENSP00000384938|refseq:XP_011511559.1|ensembl:ENSG00000114423(gene)|ensembl:ENST00000394030(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018193"(peptidyl-amino acid modification)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042110"(T cell activation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:Q13191|rcsb pdb:2AK5|rcsb pdb:2BZ8|rcsb pdb:2DO6|rcsb pdb:2J6F|rcsb pdb:2JNH|rcsb pdb:2LDR|rcsb pdb:2OOA|rcsb pdb:2OOB|rcsb pdb:3PFV|rcsb pdb:3VGO|rcsb pdb:3ZNI|reactome:R-HSA-983168|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|dip:DIP-33091N|entrezgene/locuslink:868(identity)	ensembl:ENSG00000160310(gene)|ensembl:ENST00000451211(transcript)|intact:EBI-78458(isoform-parent)|entrezgene/locuslink:3275(identity)	intact:EBI-16432622(see-also)	-	isoform-comment:Higher expression in breast cancer tissues.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:cJ5eLH0TMyM6OtmS1sM3rhsrsIk9606	rogid:s+e1GGHPoCi3o58rrtF923d2mos9606	rigid:O/0EvqF3PUmC9iQkzv6Bal0w+KM	true	-	sufficient binding region:1-286	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00401	uniprotkb:P55345-4	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	intact:EBI-16472326|ensembl:ENSP00000411984	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:p55345-4(display_long)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472334	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N|entrezgene/locuslink:8976(identity)	ensembl:ENSG00000160310(gene)|ensembl:ENST00000451211(transcript)|intact:EBI-78458(isoform-parent)|entrezgene/locuslink:3275(identity)	intact:EBI-16429376(see-also)	-	isoform-comment:Higher expression in breast cancer tissues.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	rogid:s+e1GGHPoCi3o58rrtF923d2mos9606	rigid:7b1WLlb2BvwvxA2JxNzrUQ9dI5I	true	-	sufficient binding region:1-286	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NSC5	intact:EBI-16472306	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	-	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:"ccsb isoform id: prcc_2"(display_short)|psi-mi:EBI-16472306(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472309	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	entrezgene/locuslink:5546(identity)	intact:EBI-16438346(see-also)|intact:EBI-16438362(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:j9XRhH4ZEG79gSUCXnZokfMSv6E9606	rigid:0a5vrJ7qgMSW3cO+ihYPmNYiChY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UBB9	uniprotkb:Q9Y252	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472771	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16437375(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:z4HqwWorXLwNu5gG2mw/NVyf/nU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P15884-3	uniprotkb:Q9Y252	intact:EBI-13636688|ensembl:ENSP00000346440|ensembl:ENSP00000486670	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:p15884-3(display_long)|uniprotkb:Class B basic helix-loop-helix protein 19(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:B+(isoform synonym)|uniprotkb:TCF4(gene name)|psi-mi:TCF4(display_short)|uniprotkb:BHLHB19(gene name synonym)|uniprotkb:ITF2(gene name synonym)|uniprotkb:SEF2(gene name synonym)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472755	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-533224(isoform-parent)|ensembl:ENSG00000196628(gene)|ensembl:ENST00000354452(transcript)|ensembl:ENST00000629387(transcript)|uniprotkb:P15884-3(isoform-parent)|entrezgene/locuslink:6925(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16436891(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZNbTMfCK9F8zDtvfNHuHnQpJM7w9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:sG1I2ULJ6yENOLVLKQQpgkE9jic	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q63HR2	uniprotkb:Q9Y252	intact:EBI-949753|ensembl:ENSP00000319684|uniprotkb:A2VDF2|uniprotkb:A2VDF3|uniprotkb:A2VDI8|uniprotkb:Q2NL80|uniprotkb:Q76MW6|uniprotkb:Q7Z5T9|uniprotkb:Q8NFF9|uniprotkb:Q8NFG0|uniprotkb:Q96P25|uniprotkb:Q9NT29|uniprotkb:Q9UPS7|uniprotkb:A5PKY4	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:tns2_human(display_long)|uniprotkb:TNS2(gene name)|psi-mi:TNS2(display_short)|uniprotkb:C1 domain-containing phosphatase and tensin homolog(gene name synonym)|uniprotkb:KIAA1075(gene name synonym)|uniprotkb:TENC1(gene name synonym)|uniprotkb:Tensin-like C1 domain-containing phosphatase(gene name synonym)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472736	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000314250(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014850"(response to muscle activity)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0019900"(kinase binding)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048871"(multicellular organismal homeostasis)|interpro:IPR000980(SH2 motif)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|interpro:IPR029023|interpro:IPR033929|interpro:IPR035012|interpro:IPR035892|interpro:IPR036860|mint:Q63HR2|rcsb pdb:2DKQ|rcsb pdb:2KNO|rcsb pdb:2L6K|rcsb pdb:2LOZ|rcsb pdb:3HQC|ensembl:ENSG00000111077(gene)|refseq:NP_056134.2|refseq:NP_736610.2|refseq:NP_938072.1|entrezgene/locuslink:23371(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16436693(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:uobqTi6g78V5Iib3uRGGhqjSt7o9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:3uSAK59lF8WFNAzRmUQ/fBz4584	true	sufficient binding region:125-1409	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43865	uniprotkb:Q9Y252	intact:EBI-2371423|uniprotkb:Q2TAJ6|uniprotkb:Q502W8|uniprotkb:Q5VSM0|uniprotkb:Q6P171|uniprotkb:Q96PK4|uniprotkb:Q9UG84|uniprotkb:B4E168|ensembl:ENSP00000358814	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:sahh2_human(display_long)|uniprotkb:AHCYL1(gene name)|psi-mi:AHCYL1(display_short)|uniprotkb:DCAL(gene name synonym)|uniprotkb:XPVKONA(gene name synonym)|uniprotkb:S-adenosyl-L-homocysteine hydrolase 2(gene name synonym)|uniprotkb:DC-expressed AHCY-like molecule(gene name synonym)|uniprotkb:Putative adenosylhomocysteinase 2(gene name synonym)|uniprotkb:"IP(3)Rs binding protein released with IP(3)"(gene name synonym)|uniprotkb:IRBIT(gene name synonym)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472720	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229602.1|refseq:NP_001229603.1|refseq:NP_001229604.1|refseq:NP_001229605.1|refseq:NP_006612.2|ensembl:ENSG00000168710(gene)|ensembl:ENST00000369799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0032412"(regulation of ion transmembrane transporter activity)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:O43865|rcsb pdb:3MTG|reactome:R-HSA-112043|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695|entrezgene/locuslink:10768(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16436468(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:uwZ+P9SdKadoVn01p/b8qHp6egk9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:PgrpiW1OCByu9NHS6FKoylD/I04	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:Q9Y252	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472704	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16432268(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:vxetvP2lyRMxdj6+r1ZcYeYMfSQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6NUQ1	uniprotkb:Q9Y252	intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472688	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N|entrezgene/locuslink:60561(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16431645(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:1q8DgnV/tWtOKqV3mV+Dt8o+ZlE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UL42	uniprotkb:Q9Y252	intact:EBI-302355|uniprotkb:O94959|uniprotkb:O95145|uniprotkb:Q49A18|uniprotkb:Q9UL43|ensembl:ENSP00000429344|uniprotkb:B3KNY9	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:pnma2_human(display_long)|uniprotkb:PNMA2(gene name)|psi-mi:PNMA2(display_short)|uniprotkb:KIAA0883(gene name synonym)|uniprotkb:MA2(gene name synonym)|uniprotkb:Onconeuronal antigen Ma2(gene name synonym)|uniprotkb:Paraneoplastic neuronal antigen MM2(gene name synonym)|uniprotkb:40 kDa neuronal protein(gene name synonym)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472672	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009188.1|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026525|mint:Q9UL42|ensembl:ENSG00000240694(gene)|ensembl:ENST00000522362(transcript)|go:"GO:0005730"(nucleolus)|refseq:XP_011542667.1|entrezgene/locuslink:10687(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16431267(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GeMwoq69tYJJJc5lI0/bSAGlsCQ9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:uSCHHG1cINwFT94V5/XhfGR9HXA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TD10	uniprotkb:Q9Y252	intact:EBI-2548751|ensembl:ENSP00000333539|ensembl:ENSP00000379589|ensembl:ENSP00000444254|ensembl:ENSP00000506738|uniprotkb:Q7Z3J0|uniprotkb:Q8IV14|uniprotkb:D3DSA4	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:mipo1_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472653	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151338(gene)|ensembl:ENST00000327441(transcript)|ensembl:ENST00000396294(transcript)|ensembl:ENST00000537471(transcript)|ensembl:ENST00000684589(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR026175|mint:Q8TD10|refseq:NP_001182225.1|refseq:NP_001182226.1|refseq:NP_620059.1|refseq:XP_016876492.1|refseq:XP_016876493.1|refseq:XP_016876494.1|entrezgene/locuslink:145282(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16430073(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:X4gY7nzDtnrS2yil7QhmLH968Ug9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:ovtR6kTbGzC+XWCuMyhRoRmPbzs	true	sufficient binding region:182-442	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	intact:EBI-16472634	intact:EBI-16439278	-	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:"ccsb isoform id: rnf40_2"(display_short)|psi-mi:EBI-16472634(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472637	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	entrezgene/locuslink:9810(identity)	intact:EBI-16439693(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:c3Cz6BGjD9iUCGN9Dqytq3QCQZQ9606	rigid:fXEnWosXfBN6dNWtN7/WekbqMiA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16435576	uniprotkb:Q13671-2	-	intact:EBI-366034	psi-mi:"ccsb orf id: 53744"(display_short)|psi-mi:EBI-16435576(display_long)	psi-mi:q13671-2(display_long)|uniprotkb:RIN1(gene name)|psi-mi:RIN1(display_short)|uniprotkb:Ras inhibitor JC99(gene name synonym)|uniprotkb:Ras interaction/interference protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472618	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:140258(identity)	intact:EBI-366017(rin1_human)|entrezgene/locuslink:9610(identity)	intact:EBI-16435578(see-also)	-	isoform-comment:Shows reduced ability to bind to Ras and 14-3-3 proteins.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:z0z+FcvFPqhBOHUsErdmi55IjpY9606	rogid:6g4wEXS1EKGBUMTrLAbbjPWsmZw9606	rigid:SU2IKHXFIaFeGS7yExue9rQWOxc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16435576	uniprotkb:Q13671	-	intact:EBI-366017|uniprotkb:O15010|uniprotkb:Q00427|uniprotkb:Q96CC8|ensembl:ENSP00000310406	psi-mi:"ccsb orf id: 53744"(display_short)|psi-mi:EBI-16435576(display_long)	psi-mi:rin1_human(display_long)|uniprotkb:RIN1(gene name)|psi-mi:RIN1(display_short)|uniprotkb:Ras interaction/interference protein 1(gene name synonym)|uniprotkb:Ras inhibitor JC99(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472602	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:140258(identity)	ensembl:ENSG00000174791(gene)|ensembl:ENST00000311320(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR036860|interpro:IPR037191|reactome:R-HSA-8876198|refseq:NP_004283.2|dip:DIP-117N|entrezgene/locuslink:9610(identity)	intact:EBI-16435578(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:z0z+FcvFPqhBOHUsErdmi55IjpY9606	rogid:oj/ZbyM0Oqe0wDMlFbJHCtGzMwA9606	rigid:5MT0e4/X6I+9DYJieCkkvGjPJLU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BRK4	intact:EBI-16435574	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	-	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"ccsb isoform id: rin1_3"(display_short)|psi-mi:EBI-16435574(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472586	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	entrezgene/locuslink:9610(identity)	intact:EBI-16430576(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	rogid:RW4Tn3lN56PIlLIZX5QTF7MoqSI9606	rigid:F0WfAz0iEC65wWmO6Z5NFCMkoRo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BRK4	uniprotkb:Q13671-2	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	intact:EBI-366034	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:q13671-2(display_long)|uniprotkb:RIN1(gene name)|psi-mi:RIN1(display_short)|uniprotkb:Ras inhibitor JC99(gene name synonym)|uniprotkb:Ras interaction/interference protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472570	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	intact:EBI-366017(rin1_human)|entrezgene/locuslink:9610(identity)	intact:EBI-16430576(see-also)	-	isoform-comment:Shows reduced ability to bind to Ras and 14-3-3 proteins.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	rogid:6g4wEXS1EKGBUMTrLAbbjPWsmZw9606	rigid:G7+Vl1dIbtY5woNwEVB3hDbghUY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P50221	uniprotkb:P52756	intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684	intact:EBI-714003|uniprotkb:Q93021|uniprotkb:Q9BU14|uniprotkb:Q9UKY8|uniprotkb:Q9UL24|ensembl:ENSP00000343054|uniprotkb:B2RA45|uniprotkb:B4DM16|uniprotkb:B4DMF9|uniprotkb:B4DZ63|uniprotkb:Q9HDA6|intact:EBI-16431417	psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym)	psi-mi:rbm5_human(display_long)|uniprotkb:RNA-binding motif protein 5(gene name synonym)|uniprotkb:Putative tumor suppressor LUCA15(gene name synonym)|uniprotkb:Protein G15(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-9(gene name synonym)|uniprotkb:RBM5(gene name)|psi-mi:RBM5(display_short)|uniprotkb:H37(orf name)|uniprotkb:LUCA15(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472551	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity)	ensembl:ENSG00000003756(gene)|ensembl:ENST00000347869(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033094|interpro:IPR034991|interpro:IPR034993|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P52756|rcsb pdb:2LK0|rcsb pdb:2LK1|rcsb pdb:2LKZ|rcsb pdb:5MF9|rcsb pdb:5MFY|reactome:R-HSA-72163|refseq:NP_005769.1|refseq:XP_016860992.1|dip:DIP-47277N|entrezgene/locuslink:10181(identity)	intact:EBI-16431419(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606	rogid:LsPTpaKrGY2xtpYofHbFVXjSi/A9606	rigid:Z4fe4FjpH6sV3b5q4MwUIAn8ibM	true	-	sufficient binding region:1-546	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478	uniprotkb:Q9Y252	intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472834	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16438081(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:+1ryNgVk4q6063M6hCWnP0D29iU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:P23297	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-743686|uniprotkb:Q5T7Y3|uniprotkb:B2R5D9|ensembl:ENSP00000292169	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:s10a1_human(display_long)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100A1(gene name)|psi-mi:S100A1(display_short)|uniprotkb:S100A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473636	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	refseq:NP_006262.1|ensembl:ENSG00000160678(gene)|ensembl:ENST00000292169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|mint:P23297|rcsb pdb:2L0P|rcsb pdb:2LHL|rcsb pdb:2LLS|rcsb pdb:2LLT|rcsb pdb:2LLU|rcsb pdb:2LP2|rcsb pdb:2LP3|rcsb pdb:2LUX|rcsb pdb:2M3W|rcsb pdb:5K89|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|interpro:IPR018247|entrezgene/locuslink:6271(identity)	intact:EBI-16435790(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:cELa51qDGFnYHPBnpUhMDGYPfOk9606	rigid:uoTkRbs7ghXmE55qKOGNhCpzmuw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:A0A0S2Z4M5	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-16436147	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473617	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16440776(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:jh27oDnUQKxs0Vy9E9v4HAMHGaI	true	sufficient binding region:32-313	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:P28702	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473598	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16440776(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:pvjQ5rxty4G2+HiWcuNGK4zwLJM	true	sufficient binding region:32-313	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q2TAC2-2	uniprotkb:A0A0S2Z4M5	intact:EBI-10961624|ensembl:ENSP00000376154	intact:EBI-16436147	psi-mi:q2tac2-2(display_long)|uniprotkb:CCDC57(gene name)|psi-mi:CCDC57(display_short)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473582	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000176155(gene)|ensembl:ENST00000392343(transcript)|uniprotkb:Q2TAC2-2(isoform-parent)|intact:EBI-2808286(isoform-parent)|entrezgene/locuslink:284001(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16440246(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RWcF0hgb1geIY959JUKrLK13Jx09606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:FPIzT2OQ0XZynyzI+Z6sVnMz41I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q2TAC2-2	uniprotkb:P28702	intact:EBI-10961624|ensembl:ENSP00000376154	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:q2tac2-2(display_long)|uniprotkb:CCDC57(gene name)|psi-mi:CCDC57(display_short)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473566	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000176155(gene)|ensembl:ENST00000392343(transcript)|uniprotkb:Q2TAC2-2(isoform-parent)|intact:EBI-2808286(isoform-parent)|entrezgene/locuslink:284001(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16440246(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RWcF0hgb1geIY959JUKrLK13Jx09606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:TDnp1Dh/4VhZE0wtAoxbgXMSrb0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P28702	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473545	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16438564(see-also)|intact:EBI-16438576(see-also)|intact:EBI-16438588(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:Spwo90i0Ld+LLwwP0aq/5kexDUg	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75528	intact:EBI-16429002	intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83	-	psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473526	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1|entrezgene/locuslink:10474(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16437487(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:SWzNpDZAfZVLb+X0gEtmIZJuNiQ	true	sufficient binding region:1-369	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75528	uniprotkb:A0A0S2Z4M5	intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83	intact:EBI-16436147	psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473507	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1|entrezgene/locuslink:10474(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16437487(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:E3+0nhwqTZfRp7+KTbyTGkYkGs0	true	sufficient binding region:1-369	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75528	uniprotkb:P28702	intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473488	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1|entrezgene/locuslink:10474(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16437487(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:nLqJGLGUZLBB7TIqEA4y84A5WBc	true	sufficient binding region:1-369	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UBB9	intact:EBI-16429002	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0	-	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473472	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16437385(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:ZDB/qV1GOGb9d+JzT3ELg3BneZg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UBB9	uniprotkb:A0A0S2Z4M5	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0	intact:EBI-16436147	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473456	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16437385(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:ut+BYEf5zg2MUBg+9+6JiZE6zsE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UBB9	uniprotkb:P28702	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473440	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16437385(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:D8Nto/SRm+viLYuc46jpPDZmq1A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q05BL1	uniprotkb:P28702	intact:EBI-11952721|intact:EBI-12700013	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:q05bl1_human(display_long)|uniprotkb:TP53BP2(gene name)|psi-mi:TP53BP2(display_short)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473423	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005737"(cytoplasm)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|entrezgene/locuslink:7159(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16436408(see-also)|intact:EBI-16436418(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:LA1UvPUs8vUyy7hDTxjj8DevaY89606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:nRoiusv6Em8hw9MlOBP0Z8uhb0E	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96RI1-1	intact:EBI-16429002	intact:EBI-12417284|ensembl:ENSP00000376712|ensembl:ENSP00000496908	-	psi-mi:q96ri1-1(display_long)|uniprotkb:NR1H4(gene name)|psi-mi:NR1H4(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:FXR(gene name synonym)|uniprotkb:Farnesoid X-activated receptor(gene name synonym)|uniprotkb:Farnesol receptor HRR-1(gene name synonym)|uniprotkb:HRR1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 4(gene name synonym)|uniprotkb:RIP14(gene name synonym)|uniprotkb:FXRalpha1(isoform synonym)|uniprotkb:"FXRalpha1(+)"(isoform synonym)|uniprotkb:Retinoid X receptor-interacting protein 14(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473406	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1250177(isoform-parent)|uniprotkb:Q96RI1-1(isoform-parent)|ensembl:ENSG00000012504(gene)|ensembl:ENST00000392986(transcript)|ensembl:ENST00000648861(transcript)|entrezgene/locuslink:9971(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16436328(see-also)|intact:EBI-16436338(see-also)	isoform-comment:Produced by alternative promoter usage.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Xpym/8iahj3FgUKjQK3nt2XJZVI9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:ecEh8cm1qV5iC9MPFjh2twRJz3s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96RI1-1	uniprotkb:A0A0S2Z4M5	intact:EBI-12417284|ensembl:ENSP00000376712|ensembl:ENSP00000496908	intact:EBI-16436147	psi-mi:q96ri1-1(display_long)|uniprotkb:NR1H4(gene name)|psi-mi:NR1H4(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:FXR(gene name synonym)|uniprotkb:Farnesoid X-activated receptor(gene name synonym)|uniprotkb:Farnesol receptor HRR-1(gene name synonym)|uniprotkb:HRR1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 4(gene name synonym)|uniprotkb:RIP14(gene name synonym)|uniprotkb:FXRalpha1(isoform synonym)|uniprotkb:"FXRalpha1(+)"(isoform synonym)|uniprotkb:Retinoid X receptor-interacting protein 14(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473389	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1250177(isoform-parent)|uniprotkb:Q96RI1-1(isoform-parent)|ensembl:ENSG00000012504(gene)|ensembl:ENST00000392986(transcript)|ensembl:ENST00000648861(transcript)|entrezgene/locuslink:9971(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16436328(see-also)|intact:EBI-16436338(see-also)	isoform-comment:Produced by alternative promoter usage.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Xpym/8iahj3FgUKjQK3nt2XJZVI9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:Ak/Z1is5XBeKdEbgm2u+MxnL9T4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	uniprotkb:P28702	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473371	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16436137(see-also)|intact:EBI-16436162(see-also)|intact:EBI-16436172(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:4wWlT9MpE6l6Alp+lV9d8wZ0VTw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96S82	intact:EBI-16429002	intact:EBI-348604|uniprotkb:Q96I03|ensembl:ENSP00000378518|ensembl:ENSP00000454828|ensembl:ENSP00000457703|ensembl:ENSP00000457708|ensembl:ENSP00000500164|ensembl:ENSP00000500266|ensembl:ENSP00000500442|ensembl:ENSP00000500520|ensembl:ENSP00000500882|ensembl:ENSP00000354883|uniprotkb:D3DW57	-	psi-mi:ubl7_human(display_long)|uniprotkb:Ubiquitin-like protein SB132(gene name synonym)|uniprotkb:Bone marrow stromal cell ubiquitin-like protein(gene name synonym)|uniprotkb:UBL7(gene name)|psi-mi:UBL7(display_short)|uniprotkb:BMSCUBP(gene name synonym)|uniprotkb:SB132(orf name)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473355	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116296.1|refseq:NP_957717.1|ensembl:ENST00000361351(transcript)|ensembl:ENST00000395081(transcript)|ensembl:ENST00000564488(transcript)|ensembl:ENST00000565335(transcript)|ensembl:ENST00000567435(transcript)|ensembl:ENST00000673054(transcript)|ensembl:ENST00000673073(transcript)|ensembl:ENST00000673120(transcript)|ensembl:ENST00000673153(transcript)|ensembl:ENST00000673461(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|rcsb pdb:2CWB|rcsb pdb:2DEN|ensembl:ENSG00000138629(gene)|ensembl:ENSG00000288408(gene)|refseq:NP_001273668.1|refseq:NP_001273669.1|refseq:NP_001273670.1|refseq:NP_001273671.1|entrezgene/locuslink:84993(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16435254(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:4E0ErEIkP/AQb+OHRuOd5wbXU/s9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:ps4+jCqwt8yRLmrACxwQ/gL9BTA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96S82	uniprotkb:A0A0S2Z4M5	intact:EBI-348604|uniprotkb:Q96I03|ensembl:ENSP00000378518|ensembl:ENSP00000454828|ensembl:ENSP00000457703|ensembl:ENSP00000457708|ensembl:ENSP00000500164|ensembl:ENSP00000500266|ensembl:ENSP00000500442|ensembl:ENSP00000500520|ensembl:ENSP00000500882|ensembl:ENSP00000354883|uniprotkb:D3DW57	intact:EBI-16436147	psi-mi:ubl7_human(display_long)|uniprotkb:Ubiquitin-like protein SB132(gene name synonym)|uniprotkb:Bone marrow stromal cell ubiquitin-like protein(gene name synonym)|uniprotkb:UBL7(gene name)|psi-mi:UBL7(display_short)|uniprotkb:BMSCUBP(gene name synonym)|uniprotkb:SB132(orf name)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473339	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116296.1|refseq:NP_957717.1|ensembl:ENST00000361351(transcript)|ensembl:ENST00000395081(transcript)|ensembl:ENST00000564488(transcript)|ensembl:ENST00000565335(transcript)|ensembl:ENST00000567435(transcript)|ensembl:ENST00000673054(transcript)|ensembl:ENST00000673073(transcript)|ensembl:ENST00000673120(transcript)|ensembl:ENST00000673153(transcript)|ensembl:ENST00000673461(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|rcsb pdb:2CWB|rcsb pdb:2DEN|ensembl:ENSG00000138629(gene)|ensembl:ENSG00000288408(gene)|refseq:NP_001273668.1|refseq:NP_001273669.1|refseq:NP_001273670.1|refseq:NP_001273671.1|entrezgene/locuslink:84993(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16435254(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:4E0ErEIkP/AQb+OHRuOd5wbXU/s9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:s68nk+FBO2Y8ApqAtE08fYGBfNM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96S82	uniprotkb:P28702	intact:EBI-348604|uniprotkb:Q96I03|ensembl:ENSP00000378518|ensembl:ENSP00000454828|ensembl:ENSP00000457703|ensembl:ENSP00000457708|ensembl:ENSP00000500164|ensembl:ENSP00000500266|ensembl:ENSP00000500442|ensembl:ENSP00000500520|ensembl:ENSP00000500882|ensembl:ENSP00000354883|uniprotkb:D3DW57	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:ubl7_human(display_long)|uniprotkb:Ubiquitin-like protein SB132(gene name synonym)|uniprotkb:Bone marrow stromal cell ubiquitin-like protein(gene name synonym)|uniprotkb:UBL7(gene name)|psi-mi:UBL7(display_short)|uniprotkb:BMSCUBP(gene name synonym)|uniprotkb:SB132(orf name)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473323	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116296.1|refseq:NP_957717.1|ensembl:ENST00000361351(transcript)|ensembl:ENST00000395081(transcript)|ensembl:ENST00000564488(transcript)|ensembl:ENST00000565335(transcript)|ensembl:ENST00000567435(transcript)|ensembl:ENST00000673054(transcript)|ensembl:ENST00000673073(transcript)|ensembl:ENST00000673120(transcript)|ensembl:ENST00000673153(transcript)|ensembl:ENST00000673461(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|rcsb pdb:2CWB|rcsb pdb:2DEN|ensembl:ENSG00000138629(gene)|ensembl:ENSG00000288408(gene)|refseq:NP_001273668.1|refseq:NP_001273669.1|refseq:NP_001273670.1|refseq:NP_001273671.1|entrezgene/locuslink:84993(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16435254(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:4E0ErEIkP/AQb+OHRuOd5wbXU/s9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:DsdsCLGE5OF2EhbnASThoaDjZB8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P10276	intact:EBI-16429002	intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649	-	psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473306	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|entrezgene/locuslink:5914(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16434599(see-also)|intact:EBI-16434609(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:4kDCKtuLkf0wlVGM7fEYPAz7XSo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12800	intact:EBI-16429002	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	-	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473290	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16434047(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:W2N8aPS3ik2EnT7ofcHvXTjVB7w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:A0A0S2Z4M5	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-16436147	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473274	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16434047(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:dkX0qokVhXCSmRLytr7irJxVpbY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:P28702	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473258	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16434047(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:/8DA4bc0MGrP1CpV9e/rTTBNITQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43586	uniprotkb:A0A0S2Z4M5	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	intact:EBI-16436147	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473242	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|entrezgene/locuslink:9051(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16433157(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:kI0whDKhu286XxONvjj+s6UKf6Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43586	uniprotkb:P28702	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473226	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|entrezgene/locuslink:9051(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16433157(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:uBeZTkrOBp4shfWG8lV/0Ae7ZIs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:A0A0S2Z4M5	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-16436147	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473209	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16433077(see-also)|intact:EBI-16433127(see-also)	crc64:609B121DA1A9DCB8	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:uAIlDYWyMrVKSYPWod9ATFWEIoQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:P28702	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473192	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16433077(see-also)|intact:EBI-16433127(see-also)	crc64:609B121DA1A9DCB8	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:1tjfvuf55zFLgyCA1QSmVJ5YATI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O94972	intact:EBI-16429002	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	-	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473176	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N|entrezgene/locuslink:4591(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16432716(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:Mv9GtBXuxejzdxuHcQp/C1q+U5k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O94972	uniprotkb:A0A0S2Z4M5	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	intact:EBI-16436147	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473160	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N|entrezgene/locuslink:4591(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16432716(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:6kN7yvvmOiOtfe/Pa78YVhghKy4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O94972	uniprotkb:P28702	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473144	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N|entrezgene/locuslink:4591(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16432716(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:iIJP/lkfE26iqBS8D0xGMnSZTNc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P28702	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473127	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16432168(see-also)|intact:EBI-16432178(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:plQD6GfJY3DxjVu8Coe02DnYpGg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	intact:EBI-16429002	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	-	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473108	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16431928(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:iFK2kTzkm8fWn4N9OtvK9Pn2vG4	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z4M5	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16436147	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473089	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16431928(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:OuNrcSL5T8+ryouUcMai+OWWHiE	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P28702	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473070	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16431928(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:Spwo90i0Ld+LLwwP0aq/5kexDUg	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P10276-2	intact:EBI-16429002	intact:EBI-10197061|ensembl:ENSP00000377643	-	psi-mi:p10276-2(display_long)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473054	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-413374(isoform-parent)|ensembl:ENSG00000131759(gene)|ensembl:ENST00000394081(transcript)|uniprotkb:P10276-2(isoform-parent)|entrezgene/locuslink:5914(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16431576(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N94HvF3F7xteoDkwcGx1TS7x+Qw9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:j4DuGIoAMgKiX61Eo9ke8ZAoWDQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96B26	intact:EBI-16429002	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	-	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473038	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N|entrezgene/locuslink:11340(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16431042(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y/cReHiPMubzNruyETohBjbRick9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:gNqubSiOBgV1QPdW910/QhgiGF8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96B26	uniprotkb:A0A0S2Z4M5	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	intact:EBI-16436147	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473022	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N|entrezgene/locuslink:11340(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16431042(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y/cReHiPMubzNruyETohBjbRick9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:l9rbsZs0kLHD1/BwsWRmNlmQAiI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96B26	uniprotkb:P28702	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473006	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N|entrezgene/locuslink:11340(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16431042(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:y/cReHiPMubzNruyETohBjbRick9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:PEjzYiZ3QgzCdr39ib9C57V7OsU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13133-3	intact:EBI-16429002	intact:EBI-11952806|ensembl:ENSP00000378793	-	psi-mi:q13133-3(display_long)|uniprotkb:NR1H3(gene name)|psi-mi:NR1H3(display_short)|uniprotkb:LXRA(gene name synonym)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472989	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-781356(isoform-parent)|uniprotkb:Q13133-3(isoform-parent)|ensembl:ENSG00000025434(gene)|ensembl:ENST00000395397(transcript)|entrezgene/locuslink:10062(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16430261(see-also)|intact:EBI-16430271(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:goIAjD2Xf+TWijq46YePOb3130s9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:jXEenehpAij/qbGbo4xfZXbKnjM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P10826-2	intact:EBI-16429002	intact:EBI-8583223|ensembl:ENSP00000332296|intact:MINT-2768912	-	psi-mi:p10826-2(display_long)|uniprotkb:RARB(gene name)|psi-mi:RARB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:HBV-activated protein(gene name synonym)|uniprotkb:NR1B2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym)|uniprotkb:RAR-epsilon(gene name synonym)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472972	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:P10826-2(isoform-parent)|ensembl:ENSG00000077092(gene)|ensembl:ENST00000330688(transcript)|intact:EBI-2568838(isoform-parent)|entrezgene/locuslink:5915(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16429684(see-also)|intact:EBI-16429694(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:SZ7/AxxaSSb8WNWvH8y4jq0Mv8g9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:ZPEwmvIE0yArGfssE3AU5UCQH74	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P10826-2	uniprotkb:A0A0S2Z4M5	intact:EBI-8583223|ensembl:ENSP00000332296|intact:MINT-2768912	intact:EBI-16436147	psi-mi:p10826-2(display_long)|uniprotkb:RARB(gene name)|psi-mi:RARB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:HBV-activated protein(gene name synonym)|uniprotkb:NR1B2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym)|uniprotkb:RAR-epsilon(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472955	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:P10826-2(isoform-parent)|ensembl:ENSG00000077092(gene)|ensembl:ENST00000330688(transcript)|intact:EBI-2568838(isoform-parent)|entrezgene/locuslink:5915(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16429684(see-also)|intact:EBI-16429694(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:SZ7/AxxaSSb8WNWvH8y4jq0Mv8g9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:pIqpOpn9mMe94H9jcCbFdkD0F/w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	intact:EBI-16429002	intact:EBI-10172526|ensembl:ENSP00000413976	-	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"ccsb isoform id: rxrb_4"(display_short)|psi-mi:EBI-16429002(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472936	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	entrezgene/locuslink:6257(identity)	intact:EBI-16429498(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:Vq69a0rJ8Ic7TwJaNhgz3BF/BL09606	rigid:l90SdhBXVORV0RX+oyPrIx0vICM	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:A0A0S2Z4M5	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-16436147	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472917	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16429498(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:U/bGqc8FqDTsJzm6AGe9yy5Bxqc	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P28702	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472898	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16429498(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:uk8sqgJ7JAIRxXYfMYMiXx2IhUQ	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15162	uniprotkb:A0A0S2Z4M5	intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8	intact:EBI-16436147	psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym)	psi-mi:a0a0s2z4m5_human(display_long)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472882	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|entrezgene/locuslink:6257(identity)	intact:EBI-16429004(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:ahP5N+EM8WYJC9d1uayPKhpH9gI9606	rigid:Mkn2AgMP1/SKgiO2ffOJmB56j40	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15162	uniprotkb:P28702	intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8	intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199	psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym)	psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472866	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity)	refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity)	intact:EBI-16429004(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606	rigid:8mbSyibJVly/ouHGbeptZwsiyVU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:Q9Y252	intact:EBI-16439278	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16472850	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168|entrezgene/locuslink:6049(identity)	intact:EBI-16439703(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	rigid:zLRXOfUDZX9OmdtNFfhnoRB8c18	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96B96	uniprotkb:P04271	intact:EBI-7055862|ensembl:ENSP00000233047|ensembl:ENSP00000261388|ensembl:ENSP00000460687|ensembl:ENSP00000492164|ensembl:ENSP00000492501|ensembl:ENSP00000491056|intact:MINT-8163962|intact:MINT-8201794|uniprotkb:A6NMA9|uniprotkb:O00323|uniprotkb:B4DEC1	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	psi-mi:ldaf1_human(display_long)|uniprotkb:LDAF1(gene name)|psi-mi:LDAF1(display_short)|uniprotkb:Promethin(gene name synonym)|uniprotkb:TMEM159(gene name synonym)|uniprotkb:Transmembrane protein 159(gene name synonym)	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473668	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001288698.1|refseq:NP_001288700.1|refseq:NP_001288702.1|refseq:NP_001288703.1|refseq:NP_001288704.1|ensembl:ENSG00000011638(gene)|ensembl:ENSG00000283997(gene)|ensembl:ENST00000233047(transcript)|ensembl:ENST00000261388(transcript)|ensembl:ENST00000572599(transcript)|ensembl:ENST00000638934(transcript)|ensembl:ENST00000640188(transcript)|ensembl:ENST00000640514(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140042"(lipid droplet formation)|interpro:IPR029709|mint:Q96B96|refseq:NP_065155.3|refseq:XP_005255496.1|refseq:XP_006721129.1|entrezgene/locuslink:57146(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1|entrezgene/locuslink:6285(identity)	intact:EBI-16433197(see-also)	comment:mint	-	comment:"Evidence for isoform CCSB isoform ID: S100B_1 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qDMjn8OVxY8eRUFJTc8hxD3Tk0c9606	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	rigid:0BTil7T0QqJyCIlGs0FUbTjzOgg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WW34-2	uniprotkb:P04271	intact:EBI-11528917|ensembl:ENSP00000369959	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	psi-mi:q8ww34-2(display_long)|uniprotkb:TMEM239(gene name)|psi-mi:TMEM239(display_short)	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473652	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-9675724(isoform-parent)|uniprotkb:Q8WW34-2(isoform-parent)|ensembl:ENSG00000198326(gene)|ensembl:ENST00000380585(transcript)|entrezgene/locuslink:100288797(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1|entrezgene/locuslink:6285(identity)	intact:EBI-16432656(see-also)	isoform-comment:No experimental confirmation available.	-	comment:"Evidence for isoform CCSB isoform ID: S100B_1 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1VqWIwPpWs6WjW8eDoJUHz2pegw9606	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	rigid:vo0sxxLMrrw40b4ACaH0jA5OcP0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P0C7W6	uniprotkb:A0A0S2Z4E5	intact:EBI-2548868|ensembl:ENSP00000329860	intact:EBI-16432288	psi-mi:cc172_human(display_long)|uniprotkb:CCDC172(gene name)|psi-mi:CCDC172(display_short)|uniprotkb:C10orf96(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474588	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_940917.1|ensembl:ENSG00000182645(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0097225"(sperm midpiece)|interpro:IPR029618|mint:P0C7W6|ensembl:ENST00000333254(transcript)|refseq:XP_016871695.1|entrezgene/locuslink:374355(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16440716(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JAaMYXob1bjFtiCvHmuzgCvq+FU9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:HJRl3l20mQQ31+TuorpRv/6xzDs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P29034	uniprotkb:A8MRB1	intact:EBI-752230|uniprotkb:O00266|uniprotkb:Q3KRB9|uniprotkb:Q5RHS8|uniprotkb:Q9BU83|ensembl:ENSP00000357697|ensembl:ENSP00000357698|ensembl:ENSP00000357699|ensembl:ENSP00000473260	intact:EBI-16432654|ensembl:ENSP00000356038	psi-mi:s10a2_human(display_long)|uniprotkb:S100 calcium-binding protein A2(gene name synonym)|uniprotkb:CAN19(gene name synonym)|uniprotkb:S100A2(gene name)|psi-mi:S100A2(display_short)|uniprotkb:S100L(gene name synonym)|uniprotkb:Protein S-100L(gene name synonym)	psi-mi:a8mrb1_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473714	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005969.1|ensembl:ENSG00000196754(gene)|ensembl:ENST00000368708(transcript)|ensembl:ENST00000368709(transcript)|ensembl:ENST00000368710(transcript)|ensembl:ENST00000487430(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR034325|mint:P29034|rcsb pdb:2RGI|rcsb pdb:4DUQ|entrezgene/locuslink:6273(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000367071(transcript)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR026790|entrezgene/locuslink:6285(identity)	intact:EBI-16434379(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: S100B_2 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:QcJWxtqLrbXj++33nNw9nHxj5oE9606	rogid:YQrqesg+7sfVz8LrMVmDv6yU0lI9606	rigid:CqF/wkpANeHcXuhJVWYTy+nPryM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z4E5	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16432288	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474553	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16438600(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:6tEx4D9xL4/iiA5+4O3Ca+I1epM	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z4F2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16429215	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z4f2_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474534	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR038096|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16438600(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:g9OLRu1IBFwrYMH4lg6jqGaQoPA9606	rigid:1sbTnPwVeX2VeHR7zNDxytGnjMI	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16437007	uniprotkb:Q15561	-	intact:EBI-747736|ensembl:ENSP00000352926|uniprotkb:Q92883|uniprotkb:Q96BK2|uniprotkb:Q6MZR9|uniprotkb:H0Y308|uniprotkb:Q8NEV5	psi-mi:"ccsb orf id: 56711"(display_short)|psi-mi:EBI-16437007(display_long)	psi-mi:tead4_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)|uniprotkb:RTEF1(gene name synonym)|uniprotkb:TCF13L1(gene name synonym)|uniprotkb:TEF3(gene name synonym)|uniprotkb:TEA domain family member 4(gene name synonym)|uniprotkb:Transcription factor RTEF-1(gene name synonym)|uniprotkb:Transcription factor 13-like 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474514	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:386682(identity)	refseq:NP_003204.2|refseq:NP_958849.1|refseq:NP_958851.1|ensembl:ENSG00000197905(gene)|ensembl:ENST00000359864(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0035329"(hippo signaling)|go:"GO:0048568"(embryonic organ development)|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|interpro:IPR027255|interpro:IPR038096|interpro:IPR041086|rcsb pdb:5GZB|rcsb pdb:5NO6|rcsb pdb:5OAQ|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6Q2X|rcsb pdb:6Q36|rcsb pdb:6SEN|reactome:R-HSA-2032785|rcsb pdb:6SEO|reactome:R-HSA-8951671|dip:DIP-61626N|entrezgene/locuslink:7004(identity)	intact:EBI-16437079(see-also)|intact:EBI-16437089(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TyoW1FiRm0mclGU0YkO2RWsRGo9606	rogid:DSb1zdydvEWM1RQ8uRwOJ7dX6AE9606	rigid:dyzmVQ3eU6SSsv0eMArtihg57FQ	true	-	sufficient binding region:74-434	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:Q15561	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-747736|ensembl:ENSP00000352926|uniprotkb:Q92883|uniprotkb:Q96BK2|uniprotkb:Q6MZR9|uniprotkb:H0Y308|uniprotkb:Q8NEV5	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:tead4_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)|uniprotkb:RTEF1(gene name synonym)|uniprotkb:TCF13L1(gene name synonym)|uniprotkb:TEF3(gene name synonym)|uniprotkb:TEA domain family member 4(gene name synonym)|uniprotkb:Transcription factor RTEF-1(gene name synonym)|uniprotkb:Transcription factor 13-like 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474494	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	refseq:NP_003204.2|refseq:NP_958849.1|refseq:NP_958851.1|ensembl:ENSG00000197905(gene)|ensembl:ENST00000359864(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0035329"(hippo signaling)|go:"GO:0048568"(embryonic organ development)|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|interpro:IPR027255|interpro:IPR038096|interpro:IPR041086|rcsb pdb:5GZB|rcsb pdb:5NO6|rcsb pdb:5OAQ|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6Q2X|rcsb pdb:6Q36|rcsb pdb:6SEN|reactome:R-HSA-2032785|rcsb pdb:6SEO|reactome:R-HSA-8951671|dip:DIP-61626N|entrezgene/locuslink:7004(identity)	intact:EBI-16435184(see-also)|intact:EBI-16435194(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:DSb1zdydvEWM1RQ8uRwOJ7dX6AE9606	rigid:arzo3ovF4ZwlmJBGKatYntV/TPs	true	-	sufficient binding region:74-434	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q59EK9-3	uniprotkb:A0A0S2Z4E5	intact:EBI-11957366|ensembl:ENSP00000225441	intact:EBI-16432288	psi-mi:q59ek9-3(display_long)|uniprotkb:RUNDC3A(gene name)|psi-mi:RUNDC3A(display_short)|uniprotkb:RAP2IP(gene name synonym)|uniprotkb:RPIP8(gene name synonym)|uniprotkb:Rap2-interacting protein 8(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474477	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000108309(gene)|ensembl:ENST00000225441(transcript)|intact:EBI-747225(isoform-parent)|uniprotkb:Q59EK9-3(isoform-parent)|entrezgene/locuslink:10900(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16434527(see-also)|intact:EBI-16434539(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:KM1XwGq52oeYft6Ywt8DsEdrsE49606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:4/giA48KAix4up6LAK6oX0dtUgk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IX15-3	uniprotkb:A0A0S2Z4E5	intact:EBI-10172004|ensembl:ENSP00000453979	intact:EBI-16432288	psi-mi:q8ix15-3(display_long)|uniprotkb:HOMEZ(gene name)|psi-mi:HOMEZ(display_short)|uniprotkb:Homeodomain leucine zipper-containing factor(gene name synonym)|uniprotkb:KIAA1443(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474458	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10742083(isoform-parent)|ensembl:ENSG00000215271(gene)|ensembl:ENST00000561013(transcript)|entrezgene/locuslink:57594(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16431540(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M8cGyd/inWQJqBNkUtEfmFNDDoA9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:eKQykkdjSsLLfWGtNxicRaV5lGo	true	sufficient binding region:27-552	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IX15-3	uniprotkb:A0A0S2Z4F2	intact:EBI-10172004|ensembl:ENSP00000453979	intact:EBI-16429215	psi-mi:q8ix15-3(display_long)|uniprotkb:HOMEZ(gene name)|psi-mi:HOMEZ(display_short)|uniprotkb:Homeodomain leucine zipper-containing factor(gene name synonym)|uniprotkb:KIAA1443(gene name synonym)	psi-mi:a0a0s2z4f2_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474439	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10742083(isoform-parent)|ensembl:ENSG00000215271(gene)|ensembl:ENST00000561013(transcript)|entrezgene/locuslink:57594(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR038096|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16431540(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M8cGyd/inWQJqBNkUtEfmFNDDoA9606	rogid:g9OLRu1IBFwrYMH4lg6jqGaQoPA9606	rigid:pGudwovWrjP0v1qaFgPYK8Kb1Ow	true	sufficient binding region:27-552	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N1B4	uniprotkb:A0A0S2Z4E5	intact:EBI-2799833|ensembl:ENSP00000372697|ensembl:ENSP00000390831|ensembl:ENSP00000391197|ensembl:ENSP00000404016|ensembl:ENSP00000406988|ensembl:ENSP00000409952|uniprotkb:B4DNI9|uniprotkb:Q9NPT5|uniprotkb:Q8IUN6|uniprotkb:Q5JPA0|uniprotkb:Q53GR4|uniprotkb:Q5SQW1|uniprotkb:B0UZZ4|uniprotkb:A2BF38	intact:EBI-16432288	psi-mi:vps52_human(display_long)|uniprotkb:SACM2L(gene name synonym)|uniprotkb:SAC2 suppressor of actin mutations 2-like protein(gene name synonym)|uniprotkb:VPS52(gene name)|psi-mi:VPS52(display_short)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474423	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000223501(gene)|ensembl:ENSG00000224455(gene)|ensembl:ENSG00000225590(gene)|ensembl:ENSG00000228425(gene)|ensembl:ENSG00000236014(gene)|ensembl:ENST00000383210(transcript)|ensembl:ENST00000428608(transcript)|ensembl:ENST00000441058(transcript)|ensembl:ENST00000443860(transcript)|ensembl:ENST00000445902(transcript)|ensembl:ENST00000448042(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007041"(lysosomal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048611"(embryonic ectodermal digestive tract development)|go:"GO:0055037"(recycling endosome)|go:"GO:1990745"(EARP complex)|interpro:IPR007258(Vps52/Sac2)|reactome:R-HSA-6811440|ensembl:ENSG00000206286(gene)|refseq:NP_001276104.1|refseq:NP_072047.4|refseq:NP_001276105.1|refseq:XP_016866667.1|dip:DIP-57843N|entrezgene/locuslink:6293(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16430897(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fMptnw5eMhxv+AzDK/+mSKrL7uY9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:gYZF+lJvCRZjD1jk6qSSa7jZohY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N1B4	uniprotkb:A0A0S2Z4F2	intact:EBI-2799833|ensembl:ENSP00000372697|ensembl:ENSP00000390831|ensembl:ENSP00000391197|ensembl:ENSP00000404016|ensembl:ENSP00000406988|ensembl:ENSP00000409952|uniprotkb:B4DNI9|uniprotkb:Q9NPT5|uniprotkb:Q8IUN6|uniprotkb:Q5JPA0|uniprotkb:Q53GR4|uniprotkb:Q5SQW1|uniprotkb:B0UZZ4|uniprotkb:A2BF38	intact:EBI-16429215	psi-mi:vps52_human(display_long)|uniprotkb:SACM2L(gene name synonym)|uniprotkb:SAC2 suppressor of actin mutations 2-like protein(gene name synonym)|uniprotkb:VPS52(gene name)|psi-mi:VPS52(display_short)	psi-mi:a0a0s2z4f2_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474407	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000223501(gene)|ensembl:ENSG00000224455(gene)|ensembl:ENSG00000225590(gene)|ensembl:ENSG00000228425(gene)|ensembl:ENSG00000236014(gene)|ensembl:ENST00000383210(transcript)|ensembl:ENST00000428608(transcript)|ensembl:ENST00000441058(transcript)|ensembl:ENST00000443860(transcript)|ensembl:ENST00000445902(transcript)|ensembl:ENST00000448042(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007041"(lysosomal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048611"(embryonic ectodermal digestive tract development)|go:"GO:0055037"(recycling endosome)|go:"GO:1990745"(EARP complex)|interpro:IPR007258(Vps52/Sac2)|reactome:R-HSA-6811440|ensembl:ENSG00000206286(gene)|refseq:NP_001276104.1|refseq:NP_072047.4|refseq:NP_001276105.1|refseq:XP_016866667.1|dip:DIP-57843N|entrezgene/locuslink:6293(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR038096|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16430897(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:fMptnw5eMhxv+AzDK/+mSKrL7uY9606	rogid:g9OLRu1IBFwrYMH4lg6jqGaQoPA9606	rigid:QVeTek1yNAzu2uahVTzex68k6Z4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13077	uniprotkb:A0A0S2Z4E5	intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183	intact:EBI-16432288	psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474391	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956|entrezgene/locuslink:7185(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16430833(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:7Z/E9Nq+ZayfyPhe5vxk1vAg6W0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13077	uniprotkb:A0A0S2Z4F2	intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183	intact:EBI-16429215	psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym)	psi-mi:a0a0s2z4f2_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474375	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956|entrezgene/locuslink:7185(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR038096|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16430833(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606	rogid:g9OLRu1IBFwrYMH4lg6jqGaQoPA9606	rigid:TbloL6KVdY/cHhkYjicUjHSenuA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:A0A0S2Z4E5	-	intact:EBI-16432288	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474359	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16430660(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:9m0vty/XdtQQKCxHj6gXzJKDVo4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:A0A0S2Z4F2	-	intact:EBI-16429215	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:a0a0s2z4f2_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474343	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR038096|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16430660(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:g9OLRu1IBFwrYMH4lg6jqGaQoPA9606	rigid:jIdyl8cDQiZUY/G8ce12XqoScYk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:A0A0S2Z4E5	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16432288	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474327	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16429947(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:qZQcuFygKbrzwDrWf6Dr1ZjvNFg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:A0A0S2Z4F2	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16429215	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:a0a0s2z4f2_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474311	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR038096|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16429947(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:g9OLRu1IBFwrYMH4lg6jqGaQoPA9606	rigid:b+SLibk/KTH66WNZnAyrfMmG/FA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	uniprotkb:A0A0S2Z4E5	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	intact:EBI-16432288	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474294	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16429203(see-also)|intact:EBI-16429217(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:d9rkrGrlqzsnkxCFhth2gGO0ZjE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:A0A0S2Z511	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-16474234	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:a0a0s2z511_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474278	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	go:"GO:0000166"(nucleotide binding)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0016874"(ligase activity)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR017866|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR016102(Succinyl-CoA synthetase-like)|entrezgene/locuslink:8803(identity)	intact:EBI-16440044(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:HWHnBEzhPqGDot2oEDnj/1wEcf49606	rigid:ZoDhhl3GA5scdWNTnqp2m4dMHh0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:A0A0S2Z511	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-16474234	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:a0a0s2z511_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474262	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	go:"GO:0000166"(nucleotide binding)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0016874"(ligase activity)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR017866|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR016102(Succinyl-CoA synthetase-like)|entrezgene/locuslink:8803(identity)	intact:EBI-16439154(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:HWHnBEzhPqGDot2oEDnj/1wEcf49606	rigid:VKpBZfOOkbuSd8E6N4VBzyDxkbo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15041	uniprotkb:A0A0S2Z511	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	intact:EBI-16474234	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:a0a0s2z511_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474246	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	go:"GO:0000166"(nucleotide binding)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0016874"(ligase activity)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR017866|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR016102(Succinyl-CoA synthetase-like)|entrezgene/locuslink:8803(identity)	intact:EBI-16432904(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rogid:HWHnBEzhPqGDot2oEDnj/1wEcf49606	rigid:+EPk1Rz5UUzWkWGu6DZ4pqJ1A3w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:O00506-2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16474172|ensembl:ENSP00000384444|ensembl:ENSP00000385541	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:o00506-2(display_long)|uniprotkb:Ste20-like kinase(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474215	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	ensembl:ENSG00000115694(gene)|ensembl:ENST00000405585(transcript)|ensembl:ENST00000405883(transcript)|intact:EBI-618295(isoform-parent)|entrezgene/locuslink:10494(identity)	intact:EBI-16431986(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:pwb8CAj6GQUnAHoo11bcPTR91IM9606	rigid:ada10D0vs6KmRZXt48GiUbcuSgM	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z503	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16474153	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z503_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474196	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|entrezgene/locuslink:10494(identity)	intact:EBI-16431986(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:tvI0cMppiIA52VqBLfnbNVmtGDk9606	rigid:s9BgdiT+YbugS65tUAcUxG9k1SM	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:A0A0S2Z503	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16474153	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:a0a0s2z503_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474156	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|entrezgene/locuslink:10494(identity)	intact:EBI-16429937(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:tvI0cMppiIA52VqBLfnbNVmtGDk9606	rigid:ZB5ecBUUkZlld1C59/9+pEsgfxo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:O00506-2	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-16474172|ensembl:ENSP00000384444|ensembl:ENSP00000385541	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:o00506-2(display_long)|uniprotkb:Ste20-like kinase(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474180	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	ensembl:ENSG00000115694(gene)|ensembl:ENST00000405585(transcript)|ensembl:ENST00000405883(transcript)|intact:EBI-618295(isoform-parent)|entrezgene/locuslink:10494(identity)	intact:EBI-16429937(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:pwb8CAj6GQUnAHoo11bcPTR91IM9606	rigid:ynmpe821OEJySWD5QvOQH0f+bRw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q00013	uniprotkb:O75494	intact:EBI-711788|uniprotkb:B4DZV5|uniprotkb:Q5J7V5|uniprotkb:G3XAI1|uniprotkb:Q2TSB6|ensembl:ENSP00000358547	intact:EBI-353655|uniprotkb:Q5JRI3|uniprotkb:Q5JRI4|uniprotkb:A6NFM6|uniprotkb:A6NI42|uniprotkb:A6NIU7|uniprotkb:Q5JRH9|uniprotkb:Q5JRI2|uniprotkb:O60572|uniprotkb:Q96G09|uniprotkb:Q96P17|uniprotkb:Q5JRI0|intact:EBI-11103259|ensembl:ENSP00000420195|uniprotkb:B4DJP9	psi-mi:em55_human(display_long)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)|uniprotkb:MPP1(gene name)|psi-mi:MPP1(display_short)|uniprotkb:EMP55(gene name synonym)|uniprotkb:DXS552E(gene name synonym)	psi-mi:srs10_human(display_long)|uniprotkb:FUSIP1(gene name synonym)|uniprotkb:TASR(gene name synonym)|uniprotkb:FUS-interacting serine-arginine-rich protein 1(gene name synonym)|uniprotkb:FUSIP2(gene name synonym)|uniprotkb:TLS-associated protein with Ser-Arg repeats(gene name synonym)|uniprotkb:TLS-associated serine-arginine protein(gene name synonym)|uniprotkb:40 kDa SR-repressor protein(gene name synonym)|uniprotkb:SRSF10(gene name)|psi-mi:SRSF10(display_short)|uniprotkb:Splicing factor SRp38(gene name synonym)|uniprotkb:SFRS13A(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 13A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474137	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159932.1|refseq:NP_001159933.1|refseq:NP_001159934.1|refseq:NP_002427.1|ensembl:ENSG00000130830(gene)|ensembl:ENST00000369534(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:Q00013|rcsb pdb:2EJY|rcsb pdb:2EV8|rcsb pdb:3NEY|reactome:R-HSA-9662361|entrezgene/locuslink:4354(identity)	refseq:NP_001177936.1|refseq:NP_001177934.1|refseq:NP_001177935.1|refseq:NP_006616.1|refseq:NP_473357.1|ensembl:ENSG00000188529(gene)|ensembl:ENST00000492112(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016482"(cytosolic transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034476|interpro:IPR035979|mint:O75494|reactome:R-HSA-72163|refseq:NP_001177938.1|entrezgene/locuslink:10772(identity)	intact:EBI-16433466(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:b9QmIlmQ5SZHnOQfGSezmcvaDls9606	rogid:abrRZLYWl3wlG2rHzVZMgej5EWk9606	rigid:rhiG6mhrXwlZbpF+HggFdX+Op2w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P12757	uniprotkb:Q53HV7-2	intact:EBI-2902468|uniprotkb:A6NGT1|uniprotkb:O00464|uniprotkb:P12756|uniprotkb:Q07501|uniprotkb:B4DT50|ensembl:ENSP00000259119|ensembl:ENSP00000415243	intact:EBI-12275818|ensembl:ENSP00000243112|ensembl:ENSP00000421139|ensembl:ENSP00000421206|ensembl:ENSP00000423629	psi-mi:skil_human(display_long)|uniprotkb:SKIL(gene name)|psi-mi:SKIL(display_short)|uniprotkb:SNO(gene name synonym)|uniprotkb:Ski-related protein(gene name synonym)|uniprotkb:Ski-related oncogene(gene name synonym)	psi-mi:q53hv7-2(display_long)|uniprotkb:SMUG1(gene name)|psi-mi:SMUG1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474121	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138569.1|refseq:NP_001138570.1|refseq:NP_005405.2|refseq:NP_001234937.1|refseq:XP_005247778.1|ensembl:ENSG00000136603(gene)|ensembl:ENST00000259119(transcript)|ensembl:ENST00000458537(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016605"(PML body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070848"(response to growth factor)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028373|interpro:IPR037000|rcsb pdb:3EQ5|rcsb pdb:5C4V|reactome:R-HSA-2173795|refseq:XP_006713798.1|dip:DIP-42138N|entrezgene/locuslink:6498(identity)	uniprotkb:Q53HV7-2(isoform-parent)|intact:EBI-749970(isoform-parent)|ensembl:ENSG00000123415(gene)|ensembl:ENST00000243112(transcript)|ensembl:ENST00000506595(transcript)|ensembl:ENST00000513838(transcript)|ensembl:ENST00000514685(transcript)|uniprotkb:Q53HV7(isoform-parent)|entrezgene/locuslink:23583(identity)	intact:EBI-16429664(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CktHHQJKOG+DaY5zwy1U+2YeTmw9606	rogid:m1cNtgPOvISKrGW4fehXpyQZRrw9606	rigid:SamHd3CHkfhSOqvtd8AZg9OYfaI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJX2	uniprotkb:Q53HV7-2	intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350	intact:EBI-12275818|ensembl:ENSP00000243112|ensembl:ENSP00000421139|ensembl:ENSP00000421206|ensembl:ENSP00000423629	psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym)	psi-mi:q53hv7-2(display_long)|uniprotkb:SMUG1(gene name)|psi-mi:SMUG1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474102	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|entrezgene/locuslink:8697(identity)	uniprotkb:Q53HV7-2(isoform-parent)|intact:EBI-749970(isoform-parent)|ensembl:ENSG00000123415(gene)|ensembl:ENST00000243112(transcript)|ensembl:ENST00000506595(transcript)|ensembl:ENST00000513838(transcript)|ensembl:ENST00000514685(transcript)|uniprotkb:Q53HV7(isoform-parent)|entrezgene/locuslink:23583(identity)	intact:EBI-16429123(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	rogid:m1cNtgPOvISKrGW4fehXpyQZRrw9606	rigid:M2FVQbV3Ne8s8FbTB0r5hIJMwA4	true	sufficient binding region:7-597	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:A0A0S2Z3I3	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-16474045	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:a0a0s2z3i3_human(display_long)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474086	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395|entrezgene/locuslink:1468(identity)	intact:EBI-16435174(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:FisbtsXIhWmngIvwcYU9gLLuTwM9606	rigid:n0I1bK9llI+wGGq40vTV9PRROQY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:Q9UBX3	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-750394|uniprotkb:Q96BA1|uniprotkb:Q96IP1|uniprotkb:Q542Z3|ensembl:ENSP00000345580	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:dic_human(display_long)|uniprotkb:Solute carrier family 25 member 10(gene name synonym)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)|uniprotkb:DIC(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474070	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	refseq:NP_036272.2|refseq:NP_001257817.1|refseq:NP_001257882.1|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0071422"(succinate transmembrane transport)|ensembl:ENSG00000183048(gene)|ensembl:ENST00000350690(transcript)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006811"(ion transport)|go:"GO:0006835"(dicarboxylic acid transport)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|reactome:R-HSA-70263|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR002030(Mitochondrial brown fat uncoupling protein)|interpro:IPR018108|interpro:IPR023395|mint:Q9UBX3|reactome:R-HSA-1614517|reactome:R-HSA-428643|entrezgene/locuslink:1468(identity)	intact:EBI-16435174(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:Z9a7UxJbOLZqoCyz+5L+mbkXFqk9606	rigid:Ld3t/lXV+Iil7z3Vet3JzPctoiM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P26371	uniprotkb:A0A0S2Z3I3	intact:EBI-3958099|ensembl:ENSP00000431443|uniprotkb:Q14564|uniprotkb:Q3MIP8	intact:EBI-16474045	psi-mi:kra59_human(display_long)|uniprotkb:KRTAP5-9(gene name)|psi-mi:KRTAP5-9(display_short)|uniprotkb:KAP5.9(gene name synonym)|uniprotkb:KRN1(gene name synonym)|uniprotkb:KRTAP5.9(gene name synonym)|uniprotkb:UHSK1(gene name synonym)|uniprotkb:Keratin, cuticle, ultrahigh sulfur 1(gene name synonym)|uniprotkb:Keratin, ultra high-sulfur matrix protein A(gene name synonym)|uniprotkb:Keratin-associated protein 5.9(gene name synonym)|uniprotkb:UHS keratin A(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 5.9(gene name synonym)	psi-mi:a0a0s2z3i3_human(display_long)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474054	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000254997(gene)|ensembl:ENST00000528743(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|mint:P26371|reactome:R-HSA-6805567|refseq:NP_005544.4|entrezgene/locuslink:3846(identity)	go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395|entrezgene/locuslink:1468(identity)	intact:EBI-16431297(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:B6s6+/WKO8MfrhEgj4xz7BH/jqE9606	rogid:FisbtsXIhWmngIvwcYU9gLLuTwM9606	rigid:3B170fxEebUlWjYENXFBKQCd3Dc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P26371	uniprotkb:Q9UBX3	intact:EBI-3958099|ensembl:ENSP00000431443|uniprotkb:Q14564|uniprotkb:Q3MIP8	intact:EBI-750394|uniprotkb:Q96BA1|uniprotkb:Q96IP1|uniprotkb:Q542Z3|ensembl:ENSP00000345580	psi-mi:kra59_human(display_long)|uniprotkb:KRTAP5-9(gene name)|psi-mi:KRTAP5-9(display_short)|uniprotkb:KAP5.9(gene name synonym)|uniprotkb:KRN1(gene name synonym)|uniprotkb:KRTAP5.9(gene name synonym)|uniprotkb:UHSK1(gene name synonym)|uniprotkb:Keratin, cuticle, ultrahigh sulfur 1(gene name synonym)|uniprotkb:Keratin, ultra high-sulfur matrix protein A(gene name synonym)|uniprotkb:Keratin-associated protein 5.9(gene name synonym)|uniprotkb:UHS keratin A(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 5.9(gene name synonym)	psi-mi:dic_human(display_long)|uniprotkb:Solute carrier family 25 member 10(gene name synonym)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)|uniprotkb:DIC(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474029	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000254997(gene)|ensembl:ENST00000528743(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|mint:P26371|reactome:R-HSA-6805567|refseq:NP_005544.4|entrezgene/locuslink:3846(identity)	refseq:NP_036272.2|refseq:NP_001257817.1|refseq:NP_001257882.1|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0071422"(succinate transmembrane transport)|ensembl:ENSG00000183048(gene)|ensembl:ENST00000350690(transcript)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006811"(ion transport)|go:"GO:0006835"(dicarboxylic acid transport)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|reactome:R-HSA-70263|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR002030(Mitochondrial brown fat uncoupling protein)|interpro:IPR018108|interpro:IPR023395|mint:Q9UBX3|reactome:R-HSA-1614517|reactome:R-HSA-428643|entrezgene/locuslink:1468(identity)	intact:EBI-16431297(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:B6s6+/WKO8MfrhEgj4xz7BH/jqE9606	rogid:Z9a7UxJbOLZqoCyz+5L+mbkXFqk9606	rigid:6ys05+5fCYjheBxSzCOSNXp612U	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96DZ9-2	intact:EBI-16473978	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	-	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:"ccsb isoform id: shmt2_2"(display_short)|psi-mi:EBI-16473978(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474013	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	entrezgene/locuslink:6472(identity)	intact:EBI-16440034(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:w1DYwSuUWWCqD/w2TqGF3jPNAws9606	rigid:9/k/y6HP4Vf4qZWs+v9PrgSSDkc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q969L2	intact:EBI-16473978	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	-	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:"ccsb isoform id: shmt2_2"(display_short)|psi-mi:EBI-16473978(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473997	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240|entrezgene/locuslink:114569(identity)	entrezgene/locuslink:6472(identity)	intact:EBI-16437285(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	rogid:w1DYwSuUWWCqD/w2TqGF3jPNAws9606	rigid:t022CSVW7dkPY0AY5mixkNGVF6k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15041	intact:EBI-16473978	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	-	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"ccsb isoform id: shmt2_2"(display_short)|psi-mi:EBI-16473978(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473981	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	entrezgene/locuslink:6472(identity)	intact:EBI-16432894(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rogid:w1DYwSuUWWCqD/w2TqGF3jPNAws9606	rigid:97WVEXwq2wi+PFFoa+IQ9csMnP4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BRI3	uniprotkb:A0A0S2Z333	intact:EBI-8644112|ensembl:ENSP00000363396|intact:MINT-8163383|uniprotkb:Q71RC8	intact:EBI-16473949	psi-mi:znt2_human(display_long)|uniprotkb:SLC30A2(gene name)|psi-mi:SLC30A2(display_short)|uniprotkb:Solute carrier family 30 member 2(gene name synonym)|uniprotkb:ZNT2(gene name synonym)	psi-mi:a0a0s2z333_human(display_long)|uniprotkb:SERPING1(gene name)|psi-mi:SERPING1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473962	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000158014(gene)|ensembl:ENST00000374278(transcript)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0061090"(positive regulation of sequestering of zinc ion)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-HSA-435368|refseq:NP_001004434.1|refseq:NP_115902.1|entrezgene/locuslink:7780(identity)	go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0045916"(negative regulation of complement activation)|interpro:IPR015553(Protease inhibitor I4, serpin C1)|interpro:IPR023795|interpro:IPR023796|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR036186|entrezgene/locuslink:710(identity)	intact:EBI-16434943(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E8UyE30F1s0H0A4awhgqZ6MIEuU9606	rogid:1jC9AiVsX+YrqhHm6Iui/gFSeMQ9606	rigid:CTrhJ+M02FMnL7B3BmJVoMUFp/o	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BRI3	uniprotkb:P05155	intact:EBI-8644112|ensembl:ENSP00000363396|intact:MINT-8163383|uniprotkb:Q71RC8	intact:EBI-1223454|uniprotkb:Q547W3|uniprotkb:Q59EI5|uniprotkb:Q96FE0|uniprotkb:A6NMU0|uniprotkb:A8KAI9|uniprotkb:B2R6L5|uniprotkb:Q16304|uniprotkb:Q7Z455|uniprotkb:Q9UC49|uniprotkb:Q9UCF9|uniprotkb:B4E1F0|uniprotkb:B4E1H2|ensembl:ENSP00000278407|ensembl:ENSP00000504807	psi-mi:znt2_human(display_long)|uniprotkb:SLC30A2(gene name)|psi-mi:SLC30A2(display_short)|uniprotkb:Solute carrier family 30 member 2(gene name synonym)|uniprotkb:ZNT2(gene name synonym)	psi-mi:ic1_human(display_long)|uniprotkb:SERPING1(gene name)|psi-mi:SERPING1(display_short)|uniprotkb:C1IN(gene name synonym)|uniprotkb:C1NH(gene name synonym)|uniprotkb:C1 esterase inhibitor(gene name synonym)|uniprotkb:C1-inhibiting factor(gene name synonym)|uniprotkb:Serpin G1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473933	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000158014(gene)|ensembl:ENST00000374278(transcript)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0061090"(positive regulation of sequestering of zinc ion)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-HSA-435368|refseq:NP_001004434.1|refseq:NP_115902.1|entrezgene/locuslink:7780(identity)	refseq:NP_000053.2|refseq:NP_001027466.1|dip:DIP-45635N|ensembl:ENSG00000149131(gene)|ensembl:ENST00000278407(transcript)|ensembl:ENST00000676670(transcript)|go:"GO:0001869"(negative regulation of complement activation, lectin pathway)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007568"(aging)|go:"GO:0007596"(blood coagulation)|go:"GO:0008015"(blood circulation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045087"(innate immune response)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR015553(Protease inhibitor I4, serpin C1)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P05155|rcsb pdb:1M6Q|rcsb pdb:2OAY|rcsb pdb:5DU3|rcsb pdb:5DUQ|rcsb pdb:7AKV|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-9657689|reactome:R-HSA-977606|entrezgene/locuslink:710(identity)	intact:EBI-16434943(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E8UyE30F1s0H0A4awhgqZ6MIEuU9606	rogid:Y7cqCZ6Ryz51dsi6jM86EXdfeWc9606	rigid:cUaBrTAao5GFuvhyMqx42LdOvHc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:A0A0S2Z4S8	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-16473914	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:a0a0s2z4s8_human(display_long)|uniprotkb:SEC22C(gene name)|psi-mi:SEC22C(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473917	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	go:"GO:0005737"(cytoplasm)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|interpro:IPR011012(Longin-like)|interpro:IPR043546|entrezgene/locuslink:9117(identity)	intact:EBI-16432558(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:qtheyub4kGDZY6MAK9tpWjCdiHI9606	rigid:7l4spnIGyrZKKf4i9pFc89XAA+A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:A0A0S2Z4S0	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-16473895	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:a0a0s2z4s0_human(display_long)|uniprotkb:SEC22C(gene name)|psi-mi:SEC22C(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473898	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR043546|entrezgene/locuslink:9117(identity)	intact:EBI-16432558(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:8Jep7RaAGYriguPiEBULdHp3FkI9606	rigid:l2tQuoo8uhCb+kZsjX9ufHBMuAo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16437007	uniprotkb:D3DPN2	-	intact:EBI-16473816|ensembl:ENSP00000338346|uniprotkb:A0A0S2Z540	psi-mi:"ccsb orf id: 56711"(display_short)|psi-mi:EBI-16437007(display_long)	psi-mi:d3dpn2_human(display_long)|uniprotkb:SDC3(gene name)|psi-mi:SDC3(display_short)|uniprotkb:hCG_15913(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473879	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:386682(identity)	ensembl:ENSG00000162512(gene)|ensembl:ENST00000336798(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|interpro:IPR031194|entrezgene/locuslink:9672(identity)	intact:EBI-16437069(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TyoW1FiRm0mclGU0YkO2RWsRGo9606	rogid:gaGvolZm8Z3tcSA8ynlCh7iTu8g9606	rigid:ZkDxy8rz4lLud216K9KZJHn86SQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYR5	uniprotkb:D3DPN2	intact:EBI-10172511|uniprotkb:A0JP64|ensembl:ENSP00000366955	intact:EBI-16473816|ensembl:ENSP00000338346|uniprotkb:A0A0S2Z540	psi-mi:kra42_human(display_long)|uniprotkb:KRTAP4-2(gene name)|psi-mi:KRTAP4-2(display_short)|uniprotkb:KAP4.2(gene name synonym)|uniprotkb:KRTAP4.2(gene name synonym)|uniprotkb:Keratin-associated protein 4.2(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.2(gene name synonym)	psi-mi:d3dpn2_human(display_long)|uniprotkb:SDC3(gene name)|psi-mi:SDC3(display_short)|uniprotkb:hCG_15913(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473863	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149051.1|ensembl:ENSG00000244537(gene)|ensembl:ENST00000377726(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|reactome:R-HSA-6805567|entrezgene/locuslink:85291(identity)	ensembl:ENSG00000162512(gene)|ensembl:ENST00000336798(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|interpro:IPR031194|entrezgene/locuslink:9672(identity)	intact:EBI-16436585(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8Ecqy++IpYBBxTj/kQBOfnGxoiM9606	rogid:gaGvolZm8Z3tcSA8ynlCh7iTu8g9606	rigid://5f+bH76hol0GiGyo5Pjun0TLs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYR9	uniprotkb:D3DPN2	intact:EBI-14065470|ensembl:ENSP00000377583|ensembl:ENSP00000458927|uniprotkb:Q495J2	intact:EBI-16473816|ensembl:ENSP00000338346|uniprotkb:A0A0S2Z540	psi-mi:kra24_human(display_long)|uniprotkb:KRTAP2-4(gene name)|psi-mi:KRTAP2-4(display_short)|uniprotkb:High sulfur keratin-associated protein 2.4(gene name synonym)|uniprotkb:KAP2.4(gene name synonym)|uniprotkb:KRTAP2.4(gene name synonym)|uniprotkb:Keratin-associated protein 2.4(gene name synonym)	psi-mi:d3dpn2_human(display_long)|uniprotkb:SDC3(gene name)|psi-mi:SDC3(display_short)|uniprotkb:hCG_15913(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473847	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000213417(gene)|ensembl:ENSG00000263091(gene)|ensembl:ENST00000394015(transcript)|ensembl:ENST00000572903(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|reactome:R-HSA-6805567|refseq:NP_001158724.1|refseq:NP_149440.1|entrezgene/locuslink:85294(identity)	ensembl:ENSG00000162512(gene)|ensembl:ENST00000336798(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|interpro:IPR031194|entrezgene/locuslink:9672(identity)	intact:EBI-16436488(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:QSitkYej4+CJRhx3YsYNjKB15FY9606	rogid:gaGvolZm8Z3tcSA8ynlCh7iTu8g9606	rigid:9qfsPxReeUG1q3JdK3qDxRgyO10	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P26371	uniprotkb:D3DPN2	intact:EBI-3958099|ensembl:ENSP00000431443|uniprotkb:Q14564|uniprotkb:Q3MIP8	intact:EBI-16473816|ensembl:ENSP00000338346|uniprotkb:A0A0S2Z540	psi-mi:kra59_human(display_long)|uniprotkb:KRTAP5-9(gene name)|psi-mi:KRTAP5-9(display_short)|uniprotkb:KAP5.9(gene name synonym)|uniprotkb:KRN1(gene name synonym)|uniprotkb:KRTAP5.9(gene name synonym)|uniprotkb:UHSK1(gene name synonym)|uniprotkb:Keratin, cuticle, ultrahigh sulfur 1(gene name synonym)|uniprotkb:Keratin, ultra high-sulfur matrix protein A(gene name synonym)|uniprotkb:Keratin-associated protein 5.9(gene name synonym)|uniprotkb:UHS keratin A(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 5.9(gene name synonym)	psi-mi:d3dpn2_human(display_long)|uniprotkb:SDC3(gene name)|psi-mi:SDC3(display_short)|uniprotkb:hCG_15913(orf name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473831	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000254997(gene)|ensembl:ENST00000528743(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|mint:P26371|reactome:R-HSA-6805567|refseq:NP_005544.4|entrezgene/locuslink:3846(identity)	ensembl:ENSG00000162512(gene)|ensembl:ENST00000336798(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|interpro:IPR031194|entrezgene/locuslink:9672(identity)	intact:EBI-16431287(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:B6s6+/WKO8MfrhEgj4xz7BH/jqE9606	rogid:gaGvolZm8Z3tcSA8ynlCh7iTu8g9606	rigid:aoxfE18ZyWzdELK/CelrH783Itw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8WZ60	intact:EBI-16473794	intact:EBI-6426464|ensembl:ENSP00000341342|uniprotkb:D3DNS8|uniprotkb:Q8N5I1|uniprotkb:B2RB31|uniprotkb:Q8N892	-	psi-mi:klhl6_human(display_long)|uniprotkb:KLHL6(gene name)|psi-mi:KLHL6(display_short)	psi-mi:"ccsb isoform id: sbds_3"(display_short)|psi-mi:EBI-16473794(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473797	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172578(gene)|ensembl:ENST00000341319(transcript)|go:"GO:0002467"(germinal center formation)|go:"GO:0050853"(B cell receptor signaling pathway)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR029851|refseq:NP_569713.2|entrezgene/locuslink:89857(identity)	entrezgene/locuslink:51119(identity)	intact:EBI-16440728(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3HSrMq8OrULpGu1i53jA+tFs+xA9606	rogid:KXnpJUs1hkhqKmAUGHAutje9X2A9606	rigid:v0m4QtLF9Vq7zpk993tm+08F0h8	true	sufficient binding region:12-621	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:P04271	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473778	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1|entrezgene/locuslink:6285(identity)	intact:EBI-16439144(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: S100B_1 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	rigid:wUErtfCHTW8i4XaTH+TuzLyXNL8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P23297	uniprotkb:A8MRB1	intact:EBI-743686|uniprotkb:Q5T7Y3|uniprotkb:B2R5D9|ensembl:ENSP00000292169	intact:EBI-16432654|ensembl:ENSP00000356038	psi-mi:s10a1_human(display_long)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100A1(gene name)|psi-mi:S100A1(display_short)|uniprotkb:S100A(gene name synonym)	psi-mi:a8mrb1_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473762	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006262.1|ensembl:ENSG00000160678(gene)|ensembl:ENST00000292169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|mint:P23297|rcsb pdb:2L0P|rcsb pdb:2LHL|rcsb pdb:2LLS|rcsb pdb:2LLT|rcsb pdb:2LLU|rcsb pdb:2LP2|rcsb pdb:2LP3|rcsb pdb:2LUX|rcsb pdb:2M3W|rcsb pdb:5K89|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|interpro:IPR018247|entrezgene/locuslink:6271(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000367071(transcript)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR026790|entrezgene/locuslink:6285(identity)	intact:EBI-16437425(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: S100B_2 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:cELa51qDGFnYHPBnpUhMDGYPfOk9606	rogid:YQrqesg+7sfVz8LrMVmDv6yU0lI9606	rigid:2lNJRKvHaeoQVkyr61lU9xqBm1k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q969L2	uniprotkb:P04271	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473746	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240|entrezgene/locuslink:114569(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1|entrezgene/locuslink:6285(identity)	intact:EBI-16437275(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: S100B_1 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	rigid:gqly5ZxlKoVphTaFsHZQerGoj/A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UI14	uniprotkb:P04271	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473730	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1|entrezgene/locuslink:6285(identity)	intact:EBI-16434838(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: S100B_1 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	rigid:bEKr9JIJIFO+ykQKqUdThHicWK8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P04271	uniprotkb:A8MRB1	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	intact:EBI-16432654|ensembl:ENSP00000356038	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:a8mrb1_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16473698	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1|entrezgene/locuslink:6285(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000367071(transcript)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR026790|entrezgene/locuslink:6285(identity)	intact:EBI-16433849(see-also)	-	-	comment:"Evidence for isoform CCSB isoform ID: S100B_2 expression is provided in figureS2D."|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	rogid:YQrqesg+7sfVz8LrMVmDv6yU0lI9606	rigid:kvj3OmJXQiVuC0X4nkYTb0DenjQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P0C7W6	uniprotkb:A0A0S2Z4F2	intact:EBI-2548868|ensembl:ENSP00000329860	intact:EBI-16429215	psi-mi:cc172_human(display_long)|uniprotkb:CCDC172(gene name)|psi-mi:CCDC172(display_short)|uniprotkb:C10orf96(gene name synonym)	psi-mi:a0a0s2z4f2_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474572	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_940917.1|ensembl:ENSG00000182645(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0097225"(sperm midpiece)|interpro:IPR029618|mint:P0C7W6|ensembl:ENST00000333254(transcript)|refseq:XP_016871695.1|entrezgene/locuslink:374355(identity)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR038096|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16440716(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JAaMYXob1bjFtiCvHmuzgCvq+FU9606	rogid:g9OLRu1IBFwrYMH4lg6jqGaQoPA9606	rigid:A7n5cU4PnLzy30cEMoC9cuvtOvc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HA47-2	uniprotkb:Q9HA47-2	intact:EBI-16434682|ensembl:ENSP00000361282	intact:EBI-16434682|ensembl:ENSP00000361282	psi-mi:q9ha47-2(display_long)|uniprotkb:Cytidine monophosphokinase 1(gene name synonym)|uniprotkb:Uridine monophosphokinase 1(gene name synonym)|uniprotkb:UCK1(gene name)|psi-mi:UCK1(display_short)|uniprotkb:URK1(gene name synonym)	psi-mi:q9ha47-2(display_long)|uniprotkb:Cytidine monophosphokinase 1(gene name synonym)|uniprotkb:Uridine monophosphokinase 1(gene name synonym)|uniprotkb:UCK1(gene name)|psi-mi:UCK1(display_short)|uniprotkb:URK1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474809	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000130717(gene)|ensembl:ENST00000372208(transcript)|intact:EBI-717582(isoform-parent)|uniprotkb:Q9HA47-2(isoform-parent)|entrezgene/locuslink:83549(identity)	ensembl:ENSG00000130717(gene)|ensembl:ENST00000372208(transcript)|intact:EBI-717582(isoform-parent)|uniprotkb:Q9HA47-2(isoform-parent)|entrezgene/locuslink:83549(identity)	intact:EBI-16434688(see-also)	isoform-comment:"Ref.8 (AAH15547) sequence is in conflict in position: 180:A->T."	isoform-comment:"Ref.8 (AAH15547) sequence is in conflict in position: 180:A->T."	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZBmfkyHv6PVOkOa7ZJtebWdEOtQ9606	rogid:ZBmfkyHv6PVOkOa7ZJtebWdEOtQ9606	rigid:tiBFlDEcc4567EuaagBAdO4XKf4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	intact:EBI-16474742	-	-	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:"ccsb isoform id: tstd2_2"(display_short)|psi-mi:EBI-16474742(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474793	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	entrezgene/locuslink:158427(identity)	intact:EBI-16430672(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:AYA+VA0eqnWNNe0jPVVL7D/EY2E9606	rigid:+T8K3qdBKP8Eg18p9TvxlXtWn+s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96JM7-2	intact:EBI-16474742	intact:EBI-11985629|ensembl:ENSP00000357121|ensembl:ENSP00000436706|ensembl:ENSP00000437185	-	psi-mi:q96jm7-2(display_long)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:MBT1(gene name synonym)	psi-mi:"ccsb isoform id: tstd2_2"(display_short)|psi-mi:EBI-16474742(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474777	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96JM7-2(isoform-parent)|ensembl:ENSG00000198945(gene)|ensembl:ENST00000368139(transcript)|ensembl:ENST00000526019(transcript)|ensembl:ENST00000533560(transcript)|intact:EBI-2686809(isoform-parent)|entrezgene/locuslink:84456(identity)	entrezgene/locuslink:158427(identity)	intact:EBI-16429720(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kyV/W+LGXQyvpNVA8XqVS88scjg9606	rogid:AYA+VA0eqnWNNe0jPVVL7D/EY2E9606	rigid:6DpVutyXiUillZFxkuEI22mCI/c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2D8	intact:EBI-16474742	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	-	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"ccsb isoform id: tstd2_2"(display_short)|psi-mi:EBI-16474742(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474761	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	entrezgene/locuslink:158427(identity)	intact:EBI-16429067(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:AYA+VA0eqnWNNe0jPVVL7D/EY2E9606	rigid:5wdlBkDr2x3nWF6FFonvXYzFYv4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UKT9	intact:EBI-16474742	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	-	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"ccsb isoform id: tstd2_2"(display_short)|psi-mi:EBI-16474742(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474745	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	entrezgene/locuslink:158427(identity)	intact:EBI-16428962(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:AYA+VA0eqnWNNe0jPVVL7D/EY2E9606	rigid:b8HvF5MMUT1Iup9uvxri9+PASH0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0-2	uniprotkb:A0A0S2Z611	intact:EBI-10173939|ensembl:ENSP00000257468	intact:EBI-16474723	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:a0a0s2z611_human(display_long)|uniprotkb:TMEM67(gene name)|psi-mi:TMEM67(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474726	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	go:"GO:0016021"(integral component of membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0060271"(cilium assembly)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR019170|entrezgene/locuslink:91147(identity)	intact:EBI-16431191(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rogid:T+MPKb/Ekjn5/2LbWj6xoHUd8+I9606	rigid:WnNq68CO5tOnH7UP9KhrsNq/uzM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UMX0-2	uniprotkb:Q5HYA8	intact:EBI-10173939|ensembl:ENSP00000257468	intact:EBI-11334880|uniprotkb:B3KRU5|uniprotkb:Q8IZ06|uniprotkb:Q7Z5T8|uniprotkb:G5E9H2|uniprotkb:Q3ZCX3|uniprotkb:B3KT47|ensembl:ENSP00000314488|ensembl:ENSP00000389998	psi-mi:q9umx0-2(display_long)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)	psi-mi:mks3_human(display_long)|uniprotkb:TMEM67(gene name)|psi-mi:TMEM67(display_short)|uniprotkb:MKS3(gene name synonym)|uniprotkb:Meckel syndrome type 3 protein(gene name synonym)|uniprotkb:Transmembrane protein 67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474704	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135018(gene)|ensembl:ENST00000257468(transcript)|intact:EBI-741480(isoform-parent)|uniprotkb:Q9UMX0-2(isoform-parent)|entrezgene/locuslink:29979(identity)	go:"GO:0005813"(centrosome)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031005"(filamin binding)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR019170|reactome:R-HSA-5620912|ensembl:ENSG00000164953(gene)|ensembl:ENST00000323130(transcript)|ensembl:ENST00000453321(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|entrezgene/locuslink:91147(identity)	intact:EBI-16431191(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:CTO0JDVzIxV1y8UKs5MKuCbrAdY9606	rogid:4YrnhWM1UaytyidG1L/ikUBHZlY9606	rigid:Ev8k2ZpADf6AEO2kT6jy2JGU+/E	true	-	sufficient binding region:11-995	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96HH9	intact:EBI-16474685	intact:EBI-2832937|uniprotkb:Q9H753|uniprotkb:D3DSZ3|uniprotkb:B7Z1F2|uniprotkb:B7Z3R1|uniprotkb:B7Z6D8|uniprotkb:B7Z8T2|ensembl:ENSP00000285689	-	psi-mi:grm2b_human(display_long)|uniprotkb:GRAMD2B(gene name)|psi-mi:GRAMD2B(display_short)|uniprotkb:GRAMD3(gene name synonym)|uniprotkb:HCV NS3-transactivated protein 2(gene name synonym)|uniprotkb:NS3TP2(gene name synonym)	psi-mi:"ccsb isoform id: tmem43_2"(display_short)|psi-mi:EBI-16474685(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474688	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016865274.1|refseq:NP_001139791.1|refseq:NP_001139792.1|refseq:NP_001139793.1|refseq:NP_001139794.1|refseq:NP_076416.2|refseq:XP_005272120.1|ensembl:ENSG00000155324(gene)|ensembl:ENST00000285689(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0042802"(identical protein binding)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|entrezgene/locuslink:65983(identity)	entrezgene/locuslink:79188(identity)	intact:EBI-16433789(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:6UkVJddV5/mHpLX/rk00jMwCA+k9606	rogid:uxAcxqfUYh0DNraC4u9Jyz52/wg9606	rigid:lS0vtbmEF6jvcmGkCl8c76LN3Ec	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z6S1	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16474646	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z6s1_human(display_long)|uniprotkb:TEX9(gene name)|psi-mi:TEX9(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474665	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	entrezgene/locuslink:374618(identity)	intact:EBI-16438614(see-also)|intact:EBI-16438626(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:6fh/qjSn0/Yy9eZsqEm3hGVB8gY9606	rigid:q+FO9YM9b7P/jvVHKERhC+bXkVs	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6NUQ1	uniprotkb:A0A0S2Z6S1	intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700	intact:EBI-16474646	psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short)	psi-mi:a0a0s2z6s1_human(display_long)|uniprotkb:TEX9(gene name)|psi-mi:TEX9(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474649	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N|entrezgene/locuslink:60561(identity)	entrezgene/locuslink:374618(identity)	intact:EBI-16431659(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606	rogid:6fh/qjSn0/Yy9eZsqEm3hGVB8gY9606	rigid:0hXrLxWRcA4cTPV332DiYyhDGFw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:A0A0S2Z4E5	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-16432288	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:a0a0s2z4e5_human(display_long)|uniprotkb:TEAD4(gene name)|psi-mi:TEAD4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474629	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	interpro:IPR041086|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR000818(TEA/ATTS)|entrezgene/locuslink:7004(identity)	intact:EBI-16440888(see-also)|intact:EBI-16440900(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:C79mELdRSQO+6g3EsushmznVLBg9606	rigid:Z45z5aT8PwryAC9bG0bFDtR/WJY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q04864-2	uniprotkb:P54577	intact:EBI-10829018|ensembl:ENSP00000377989	intact:EBI-1048893|uniprotkb:O43276|uniprotkb:Q53EN1|uniprotkb:B3KWK4|uniprotkb:D3DPQ4|ensembl:ENSP00000362576	psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:syyc_human(display_long)|uniprotkb:YARS1(gene name)|psi-mi:YARS1(display_short)|uniprotkb:Tyrosyl-tRNA synthetase(gene name synonym)|uniprotkb:YARS(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475111	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity)	refseq:NP_003671.1|ensembl:ENSG00000134684(gene)|ensembl:ENST00000373477(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004831"(tyrosine-tRNA ligase activity)|go:"GO:0005153"(interleukin-8 receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006437"(tyrosyl-tRNA aminoacylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0016604"(nuclear body)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR002307(Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|rcsb pdb:1N3L|rcsb pdb:1NTG|rcsb pdb:1Q11|rcsb pdb:4Q93|rcsb pdb:4QBT|rcsb pdb:5THH|rcsb pdb:5THL|reactome:R-HSA-379716|dip:DIP-50415N|entrezgene/locuslink:8565(identity)	intact:EBI-16435802(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606	rogid:y/0Qs8iOgW5w5LVLWnCvowVpEu89606	rigid:pXubpguM35D63KpLdhNImXjQDbM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15025	uniprotkb:A0A0S2Z555	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-16475060	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:a0a0s2z555_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475095	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	interpro:IPR036045|interpro:IPR043154|entrezgene/locuslink:26276(identity)	intact:EBI-16438372(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:ihNrx9Ir+4ZSDi9Uolbp1fXCV8E9606	rigid:mUBSeXoE3g/zv8CpWHTZXpIo7q4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15025	uniprotkb:A0A0S2Z589	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-16475041	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:a0a0s2z589_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475079	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	entrezgene/locuslink:26276(identity)	intact:EBI-16438372(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:YB3/q1I8N7Ggx8pqaUE76hdAbPg9606	rigid:MThsbLDIv7OQwe22IZnHqe5Zgi4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H9C1	uniprotkb:A0A0S2Z555	intact:EBI-749080|uniprotkb:O95434|uniprotkb:Q9H7E1|uniprotkb:Q9H9I9|uniprotkb:B4DPI6|ensembl:ENSP00000339122|ensembl:ENSP00000452181|ensembl:ENSP00000452191	intact:EBI-16475060	psi-mi:spe39_human(display_long)|uniprotkb:VIPAS39(gene name)|psi-mi:VIPAS39(display_short)|uniprotkb:C14orf133(gene name synonym)|uniprotkb:SPE39(gene name synonym)|uniprotkb:VIPAR(gene name synonym)|uniprotkb:VPS33B-interacting protein in apical-basolateral polarity regulator(gene name synonym)|uniprotkb:VPS33B-interacting protein in polarity and apical restriction(gene name synonym)	psi-mi:a0a0s2z555_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475063	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180243.1|refseq:NP_001180244.1|refseq:NP_001180246.1|refseq:NP_071350.2|refseq:NP_001180245.1|ensembl:ENSG00000151445(gene)|ensembl:ENST00000343765(transcript)|ensembl:ENST00000553888(transcript)|ensembl:ENST00000557658(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR038132|interpro:IPR040057|mint:Q9H9C1|entrezgene/locuslink:63894(identity)	interpro:IPR036045|interpro:IPR043154|entrezgene/locuslink:26276(identity)	intact:EBI-16433017(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Th3K4elgRIPP7DHwIRBN+GKNOXM9606	rogid:ihNrx9Ir+4ZSDi9Uolbp1fXCV8E9606	rigid:KCIooJumEuwOCsZDypZEOZ+Of6E	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H9C1	uniprotkb:A0A0S2Z589	intact:EBI-749080|uniprotkb:O95434|uniprotkb:Q9H7E1|uniprotkb:Q9H9I9|uniprotkb:B4DPI6|ensembl:ENSP00000339122|ensembl:ENSP00000452181|ensembl:ENSP00000452191	intact:EBI-16475041	psi-mi:spe39_human(display_long)|uniprotkb:VIPAS39(gene name)|psi-mi:VIPAS39(display_short)|uniprotkb:C14orf133(gene name synonym)|uniprotkb:SPE39(gene name synonym)|uniprotkb:VIPAR(gene name synonym)|uniprotkb:VPS33B-interacting protein in apical-basolateral polarity regulator(gene name synonym)|uniprotkb:VPS33B-interacting protein in polarity and apical restriction(gene name synonym)	psi-mi:a0a0s2z589_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475044	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180243.1|refseq:NP_001180244.1|refseq:NP_001180246.1|refseq:NP_071350.2|refseq:NP_001180245.1|ensembl:ENSG00000151445(gene)|ensembl:ENST00000343765(transcript)|ensembl:ENST00000553888(transcript)|ensembl:ENST00000557658(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR038132|interpro:IPR040057|mint:Q9H9C1|entrezgene/locuslink:63894(identity)	entrezgene/locuslink:26276(identity)	intact:EBI-16433017(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Th3K4elgRIPP7DHwIRBN+GKNOXM9606	rogid:YB3/q1I8N7Ggx8pqaUE76hdAbPg9606	rigid:GAYzdWonLhs0Zj6OwhbTSDFQhH4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:A0A0S2Z5H5	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-16475012	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a0s2z5h5_human(display_long)|uniprotkb:VPS28(gene name)|psi-mi:VPS28(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475022	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0000813"(ESCRT I complex)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|interpro:IPR038358|refseq:XP_005272381.1|interpro:IPR007143(Vacuolar protein sorting-associated, VPS28)|interpro:IPR017899|interpro:IPR017898|interpro:IPR037202|interpro:IPR037206|entrezgene/locuslink:51160(identity)	intact:EBI-16438638(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:I1oHVgmyOif0+MUSGRncDDdOMDI9606	rigid:qmVhq0+Kp2TVlvSCADIOYt1ixzA	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:A0A0S2Z698	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-16474860	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:a0a0s2z698_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474991	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009166"(nucleotide catabolic process)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR035994|entrezgene/locuslink:151531(identity)	intact:EBI-16440788(see-also)|intact:EBI-16440802(see-also)|intact:EBI-16440816(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:fT+je8uPSr2lrYO4Tv4+T0O0SJ49606	rigid:vN1ipA4gQFDraWrnX06T1nviL8Q	true	sufficient binding region:32-313	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:A0A0S2Z639	intact:EBI-16439278	intact:EBI-16440814	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:a0a0s2z639_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474975	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	interpro:IPR035994|go:"GO:0003824"(catalytic activity)|go:"GO:0009116"(nucleoside metabolic process)|entrezgene/locuslink:151531(identity)	intact:EBI-16439735(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:u91e0/um6Z08kXAtXkSv8NXLOcg9606	rigid:DHHYoNcOb37ulcBGTeAl8G53sfE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:A0A0S2Z698	intact:EBI-16439278	intact:EBI-16474860	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:a0a0s2z698_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474959	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009166"(nucleotide catabolic process)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR035994|entrezgene/locuslink:151531(identity)	intact:EBI-16439735(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:fT+je8uPSr2lrYO4Tv4+T0O0SJ49606	rigid:5smZGw0i6+TQaD6i/7SDUpGfajI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	uniprotkb:A0A0S2Z6U5	intact:EBI-16439278	intact:EBI-16432858	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:a0a0s2z6u5_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474943	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0044206"(UMP salvage)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|refseq:XP_005246416.1|interpro:IPR035994|entrezgene/locuslink:151531(identity)	intact:EBI-16439735(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:VyzKKO5ec+Y8bdAeaJtLyApjOak9606	rigid:gqQDw5h56p3GTIZV2Ba9yJ5QYBQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95045-2	uniprotkb:A0A0S2Z639	intact:EBI-11528386|ensembl:ENSP00000474090	intact:EBI-16440814	psi-mi:o95045-2(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:a0a0s2z639_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474923	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10191025(isoform-parent)|ensembl:ENSG00000007001(gene)|ensembl:ENST00000605860(transcript)|uniprotkb:O95045-2(isoform-parent)|entrezgene/locuslink:151531(identity)	interpro:IPR035994|go:"GO:0003824"(catalytic activity)|go:"GO:0009116"(nucleoside metabolic process)|entrezgene/locuslink:151531(identity)	intact:EBI-16432844(see-also)|intact:EBI-16432860(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:owY6a3SJ4JVsFePCTPW+NLGK6QQ9606	rogid:u91e0/um6Z08kXAtXkSv8NXLOcg9606	rigid:pp8sXtmY1T4sW/eDS2wew/+BpBQ	true	sufficient binding region:58-374	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95045-2	uniprotkb:A0A0S2Z698	intact:EBI-11528386|ensembl:ENSP00000474090	intact:EBI-16474860	psi-mi:o95045-2(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:a0a0s2z698_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474903	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10191025(isoform-parent)|ensembl:ENSG00000007001(gene)|ensembl:ENST00000605860(transcript)|uniprotkb:O95045-2(isoform-parent)|entrezgene/locuslink:151531(identity)	go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009166"(nucleotide catabolic process)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR035994|entrezgene/locuslink:151531(identity)	intact:EBI-16432844(see-also)|intact:EBI-16432860(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:owY6a3SJ4JVsFePCTPW+NLGK6QQ9606	rogid:fT+je8uPSr2lrYO4Tv4+T0O0SJ49606	rigid:Lh/fLgss+AWGNNNNfvnAj2LugJg	true	sufficient binding region:58-374	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:A0A0S2Z639	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-16440814	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:a0a0s2z639_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474887	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	interpro:IPR035994|go:"GO:0003824"(catalytic activity)|go:"GO:0009116"(nucleoside metabolic process)|entrezgene/locuslink:151531(identity)	intact:EBI-16430061(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:u91e0/um6Z08kXAtXkSv8NXLOcg9606	rigid:TIivXsRUj8ALRNOIb/WB0GYTb84	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:A0A0S2Z698	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-16474860	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:a0a0s2z698_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474871	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009166"(nucleotide catabolic process)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR035994|entrezgene/locuslink:151531(identity)	intact:EBI-16430061(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:fT+je8uPSr2lrYO4Tv4+T0O0SJ49606	rigid:vN1ipA4gQFDraWrnX06T1nviL8Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:A0A0S2Z6U5	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-16432858	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:a0a0s2z6u5_human(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474844	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0044206"(UMP salvage)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|refseq:XP_005246416.1|interpro:IPR035994|entrezgene/locuslink:151531(identity)	intact:EBI-16430061(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:VyzKKO5ec+Y8bdAeaJtLyApjOak9606	rigid:oC4nKqUXADb9RQFLJQzVRVVcvrA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9HA47-2	uniprotkb:Q9HA47	intact:EBI-16434682|ensembl:ENSP00000361282	intact:EBI-717582|uniprotkb:Q5JT12|uniprotkb:Q6IA74|uniprotkb:Q5JT09|uniprotkb:Q5JT13|uniprotkb:Q96BJ0|uniprotkb:Q5JT10|ensembl:ENSP00000361289	psi-mi:q9ha47-2(display_long)|uniprotkb:Cytidine monophosphokinase 1(gene name synonym)|uniprotkb:Uridine monophosphokinase 1(gene name synonym)|uniprotkb:UCK1(gene name)|psi-mi:UCK1(display_short)|uniprotkb:URK1(gene name synonym)	psi-mi:uck1_human(display_long)|uniprotkb:Uridine monophosphokinase 1(gene name synonym)|uniprotkb:Cytidine monophosphokinase 1(gene name synonym)|uniprotkb:UCK1(gene name)|psi-mi:UCK1(display_short)|uniprotkb:URK1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16474825	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000130717(gene)|ensembl:ENST00000372208(transcript)|intact:EBI-717582(isoform-parent)|uniprotkb:Q9HA47-2(isoform-parent)|entrezgene/locuslink:83549(identity)	refseq:NP_001129426.1|refseq:NP_113620.1|refseq:NP_001305448.1|refseq:NP_001248379.1|refseq:NP_001248380.1|ensembl:ENSG00000130717(gene)|ensembl:ENST00000372215(transcript)|go:"GO:0004849"(uridine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0044206"(UMP salvage)|go:"GO:0044211"(CTP salvage)|interpro:IPR000764(Uridine kinase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417|interpro:IPR029920|rcsb pdb:2JEO|rcsb pdb:2UVQ|reactome:R-HSA-73614|entrezgene/locuslink:83549(identity)	intact:EBI-16434688(see-also)	isoform-comment:"Ref.8 (AAH15547) sequence is in conflict in position: 180:A->T."	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZBmfkyHv6PVOkOa7ZJtebWdEOtQ9606	rogid:SPTYxIH9wm04Tx4T1A+EV7HZ4Yk9606	rigid:mU8ztoEQaxor3Y/WJQBUe1bVML4	true	-	sufficient binding region:1-232	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P0C7X2	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475501	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16429588(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:13DNDdpoLi9/tB8ON/n2pUOPSyw	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BQY4	uniprotkb:A0A0S2Z564	intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441	intact:EBI-16475127	psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym)	psi-mi:a0a0s2z564_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475134	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|entrezgene/locuslink:27033(identity)	intact:EBI-16432666(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606	rogid:dXjoGOAoXzVBI3tXnuT+/JmnJIM9606	rigid:aS1+FX83Ip8ZX9aWsk02EQem6/I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	uniprotkb:P0C7X2	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475469	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16429227(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:E4vr9aj5p7CCi/53FLdmZPadu4g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:A0A0S2Z6P0	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-16429989	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475453	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16429089(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:iCF5+8S6UpoHwjr/vLJ9+G2sEJI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:P0C7X2	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475437	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16429089(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:d2EC12ai7pLHxgPaxeCvObrf+IQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75525	uniprotkb:A0A0S2Z6P0	intact:EBI-722504|uniprotkb:Q6NUL8|uniprotkb:Q9UPA8|ensembl:ENSP00000348108	intact:EBI-16429989	psi-mi:khdr3_human(display_long)|uniprotkb:Sam68-like mammalian protein 2(gene name synonym)|uniprotkb:Sam68-like phosphotyrosine protein(gene name synonym)|uniprotkb:RNA-binding protein T-Star(gene name synonym)|uniprotkb:KHDRBS3(gene name)|psi-mi:KHDRBS3(display_short)|uniprotkb:SALP(gene name synonym)|uniprotkb:SLM2(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475421	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006549.1|ensembl:ENSG00000131773(gene)|ensembl:ENST00000355849(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:O75525|rcsb pdb:5EL3|rcsb pdb:5ELR|rcsb pdb:5ELS|rcsb pdb:5ELT|rcsb pdb:5EMO|reactome:R-HSA-8849468|entrezgene/locuslink:10656(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16429035(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9ZoB3JVp0Q9nxeFRsmWhNThzWoE9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:efCBE+x1hLNa4AQxrv3yLIz/l4s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75525	uniprotkb:P0C7X2	intact:EBI-722504|uniprotkb:Q6NUL8|uniprotkb:Q9UPA8|ensembl:ENSP00000348108	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:khdr3_human(display_long)|uniprotkb:Sam68-like mammalian protein 2(gene name synonym)|uniprotkb:Sam68-like phosphotyrosine protein(gene name synonym)|uniprotkb:RNA-binding protein T-Star(gene name synonym)|uniprotkb:KHDRBS3(gene name)|psi-mi:KHDRBS3(display_short)|uniprotkb:SALP(gene name synonym)|uniprotkb:SLM2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475405	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006549.1|ensembl:ENSG00000131773(gene)|ensembl:ENST00000355849(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:O75525|rcsb pdb:5EL3|rcsb pdb:5ELR|rcsb pdb:5ELS|rcsb pdb:5ELT|rcsb pdb:5EMO|reactome:R-HSA-8849468|entrezgene/locuslink:10656(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16429035(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9ZoB3JVp0Q9nxeFRsmWhNThzWoE9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:0LyYoJdbIGqZ6fgrBwqqpyElgfI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15162	uniprotkb:A0A0S2Z6P0	intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8	intact:EBI-16429989	psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475389	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16429025(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:jRHI67I5lOmWoOXVBatytEwalGs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15162	uniprotkb:P0C7X2	intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475373	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16429025(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:eCuRq+1r0BQmzAhW61hLbDO29CM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P17040-4	uniprotkb:Q969J2	intact:EBI-16440054|ensembl:ENSP00000362512	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	psi-mi:p17040-4(display_long)|uniprotkb:Zinc finger protein 31(gene name synonym)|uniprotkb:Zinc finger protein 360(gene name synonym)|uniprotkb:Zinc finger protein KOX29(gene name synonym)|uniprotkb:ZSCAN20(gene name)|psi-mi:ZSCAN20(display_short)|uniprotkb:KOX29(gene name synonym)|uniprotkb:ZNF31(gene name synonym)|uniprotkb:ZNF360(gene name synonym)	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475357	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000121903(gene)|ensembl:ENST00000373413(transcript)|intact:EBI-745838(isoform-parent)|entrezgene/locuslink:7579(identity)	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1|entrezgene/locuslink:387032(identity)	intact:EBI-16440062(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:qHCR8fgETOY4paUgFW7PPM/aGT89606	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	rigid:yktMyOELVtXF00ECaS9/pFP2Tj4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O15151	uniprotkb:Q969J2	intact:EBI-398437|uniprotkb:Q32SL2|uniprotkb:Q6GS18|uniprotkb:Q8IV83|intact:EBI-3932059|uniprotkb:Q2M2Y2|intact:EBI-28988565|ensembl:ENSP00000356150	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	psi-mi:mdm4_human(display_long)|uniprotkb:MDM4(gene name)|psi-mi:MDM4(display_short)|uniprotkb:MDMX(gene name synonym)|uniprotkb:p53-binding protein Mdm4(gene name synonym)|uniprotkb:Mdm2-like p53-binding protein(gene name synonym)|uniprotkb:Protein Mdmx(gene name synonym)|uniprotkb:Double minute 4 protein(gene name synonym)	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475341	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002384.2|refseq:NP_001191101.1|refseq:NP_001191100.1|ensembl:ENSP00000356150|ensembl:ENST00000367183|ensembl:ENSP00000356151|ensembl:ENST00000454264|ensembl:ENSP00000396840|refseq:NP_001265445.1|refseq:NP_001265446.1|refseq:NP_001265447.1|refseq:NP_001265448.1|dip:DIP-24199N|reactome:R-HSA-69541|reactome:R-HSA-6804760|ensembl:ENSG00000198625(gene)|ensembl:ENST00000367182(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003170"(heart valve development)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015458(MDM4/MDMX protein)|interpro:IPR016495(p53 negative regulator Mdm2/Mdm4)|interpro:IPR036443|interpro:IPR036885|mint:O15151|rcsb pdb:2CR8|rcsb pdb:2MWY|rcsb pdb:2N06|rcsb pdb:2N0U|rcsb pdb:2N0W|rcsb pdb:2N14|rcsb pdb:2VJE|rcsb pdb:2VJF|rcsb pdb:2VYR|rcsb pdb:3DAB|rcsb pdb:3EQY|rcsb pdb:3FDO|rcsb pdb:3FE7|rcsb pdb:3FEA|rcsb pdb:3JZO|rcsb pdb:3JZP|rcsb pdb:3JZQ|rcsb pdb:3LBJ|rcsb pdb:3MQR|rcsb pdb:3U15|rcsb pdb:4RXZ|rcsb pdb:5MNJ|rcsb pdb:5UML|rcsb pdb:5VK1|rcsb pdb:6Q9Q|rcsb pdb:6Q9S|rcsb pdb:6Q9U|rcsb pdb:6Q9W|rcsb pdb:6Q9Y|rcsb pdb:7C3Q|rcsb pdb:7C3Y|rcsb pdb:7C44|rcsb pdb:7EL4|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-5689880|reactome:R-HSA-6804756|reactome:R-HSA-6804757|entrezgene/locuslink:4194(identity)	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1|entrezgene/locuslink:387032(identity)	intact:EBI-16431554(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:zAL03wG+qlPT5folNjx1ZUJhx/A9606	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	rigid:1D5tAwqqnvalY143E54lkEONOCE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6P088	uniprotkb:Q969J2	intact:EBI-10196963|ensembl:ENSP00000438048	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	psi-mi:q6p088_human(display_long)|uniprotkb:ZNF483(gene name)|psi-mi:ZNF483(display_short)	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475325	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016869828.1|ensembl:ENSG00000173258(gene)|ensembl:ENST00000355824(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR036051|interpro:IPR038269|entrezgene/locuslink:158399(identity)	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1|entrezgene/locuslink:387032(identity)	intact:EBI-16431096(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:SXAiqzd6g4YN0PLaLlPAbSnBTMU9606	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	rigid:CjDEwT5mY3l5+Tln8Xtmx0gBdmA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	uniprotkb:A0A0S2Z6H0	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	intact:EBI-16428984	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:a0a0s2z6h0_human(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475309	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	interpro:IPR041367|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002999(Tudor)|interpro:IPR036855|interpro:IPR043560|entrezgene/locuslink:84619(identity)	intact:EBI-16436214(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:ezg+DgS3ra4uCIomSOVb3WD4oxU9606	rigid:5Z0yNONIUHLT6bUuHxBeQPDQRz4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7L4P6	uniprotkb:Q8N5A5-2	intact:EBI-724373|ensembl:ENSP00000360899|uniprotkb:D3DQ27|uniprotkb:Q96A62|uniprotkb:Q9HAI3|intact:EBI-3044085	intact:EBI-10183064|ensembl:ENSP00000348242|ensembl:ENSP00000358984|ensembl:ENSP00000391176	psi-mi:bend5_human(display_long)|uniprotkb:BEND5(gene name)|psi-mi:BEND5(display_short)|uniprotkb:C1orf165(gene name synonym)	psi-mi:q8n5a5-2(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)|uniprotkb:G patch domain-containing protein 6(gene name synonym)|uniprotkb:GPATC6(gene name synonym)|uniprotkb:GPATCH6(gene name synonym)|uniprotkb:KIAA1847(gene name synonym)|uniprotkb:ZC3H9(gene name synonym)|uniprotkb:ZC3HDC9(gene name synonym)|uniprotkb:ZIP(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 9(gene name synonym)|uniprotkb:Zinc finger and G patch domain-containing protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475293	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078879.2|ensembl:ENSG00000162373(gene)|ensembl:ENST00000371833(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR018379|interpro:IPR040391|mint:Q7L4P6|refseq:NP_001289011.1|refseq:XP_011540444.1|refseq:XP_016857823.1|entrezgene/locuslink:79656(identity)	intact:EBI-3439227(isoform-parent)|ensembl:ENSG00000197114(gene)|ensembl:ENST00000355969(transcript)|ensembl:ENST00000369967(transcript)|ensembl:ENST00000448100(transcript)|uniprotkb:Q8N5A5-2(isoform-parent)|entrezgene/locuslink:84619(identity)	intact:EBI-16435224(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:R6OwgNU76FX6tqLRdHVmzEgK8EE9606	rogid:DoBoYNv5QTlYVrPNdQvRKrcyeqA9606	rigid:2q8uLKQ1+8gLn/nJa6JM6jdeycc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6FHY5	intact:EBI-16475183	intact:EBI-16439278	-	psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)	psi-mi:"ccsb isoform id: zcwpw1_5"(display_short)|psi-mi:EBI-16475183(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475275	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity)	entrezgene/locuslink:55063(identity)	intact:EBI-16439747(see-also)|intact:EBI-16439759(see-also)|intact:EBI-16439769(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606	rogid:CH+EjdC75gRp4VN7ew7pFgp2WsU9606	rigid:6eFBKinLIBak/o2vAtYUyuKrDNM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	intact:EBI-16475183	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	-	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:"ccsb isoform id: zcwpw1_5"(display_short)|psi-mi:EBI-16475183(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475259	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	entrezgene/locuslink:55063(identity)	intact:EBI-16436997(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:CH+EjdC75gRp4VN7ew7pFgp2WsU9606	rigid:oIgQrd9USLLOff06/8w/7mXXRVw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	uniprotkb:A0A0S2Z5E1	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	intact:EBI-16439757	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:a0a0s2z5e1_human(display_long)|uniprotkb:ZCWPW1(gene name)|psi-mi:ZCWPW1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475243	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	go:"GO:0008270"(zinc ion binding)|interpro:IPR000313(PWWP)|interpro:IPR011124(Zinc finger, CW-type)|interpro:IPR042778|entrezgene/locuslink:55063(identity)	intact:EBI-16436997(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:kd2aWGkvURF0tE0/nLpaz7LijXc9606	rigid:vhpu/2MbKHxQh4pQzVQ0H7e2NW0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	uniprotkb:A0A0S2Z5J5	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	intact:EBI-16475219	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:a0a0s2z5j5_human(display_long)|uniprotkb:ZCWPW1(gene name)|psi-mi:ZCWPW1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475227	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	go:"GO:0008270"(zinc ion binding)|interpro:IPR000313(PWWP)|interpro:IPR011124(Zinc finger, CW-type)|interpro:IPR042778|entrezgene/locuslink:55063(identity)	intact:EBI-16436997(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:p//ETQJAR8nI0LAzxAcx/GOpaJA9606	rigid:zweV7vJSqTb6rapt8bHCXadtp2U	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08AM6	uniprotkb:Q9H0M4-4	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	intact:EBI-16429732|ensembl:ENSP00000419187	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:q9h0m4-4(display_long)|uniprotkb:ZCWPW1(gene name)|psi-mi:ZCWPW1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475203	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity)	ensembl:ENST00000490721(transcript)|ensembl:ENSG00000078487(gene)|intact:EBI-8659823(isoform-parent)|entrezgene/locuslink:55063(identity)	intact:EBI-16436997(see-also)	-	isoform-comment:No experimental confirmation available.	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rogid:pfDCuBoXLZLhuU/JiaUzpFUAmbU9606	rigid:r8+ua2OWvjHqCjqpkcjmBnzU5WU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96JM7-2	intact:EBI-16475183	intact:EBI-11985629|ensembl:ENSP00000357121|ensembl:ENSP00000436706|ensembl:ENSP00000437185	-	psi-mi:q96jm7-2(display_long)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:MBT1(gene name synonym)	psi-mi:"ccsb isoform id: zcwpw1_5"(display_short)|psi-mi:EBI-16475183(display_long)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475186	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96JM7-2(isoform-parent)|ensembl:ENSG00000198945(gene)|ensembl:ENST00000368139(transcript)|ensembl:ENST00000526019(transcript)|ensembl:ENST00000533560(transcript)|intact:EBI-2686809(isoform-parent)|entrezgene/locuslink:84456(identity)	entrezgene/locuslink:55063(identity)	intact:EBI-16429737(see-also)|intact:EBI-16429749(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kyV/W+LGXQyvpNVA8XqVS88scjg9606	rogid:CH+EjdC75gRp4VN7ew7pFgp2WsU9606	rigid:tjq25KMBU4bcScfnO2ItbNfnIZs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96JM7-2	uniprotkb:A0A0S2Z5E1	intact:EBI-11985629|ensembl:ENSP00000357121|ensembl:ENSP00000436706|ensembl:ENSP00000437185	intact:EBI-16439757	psi-mi:q96jm7-2(display_long)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:MBT1(gene name synonym)	psi-mi:a0a0s2z5e1_human(display_long)|uniprotkb:ZCWPW1(gene name)|psi-mi:ZCWPW1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475166	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q96JM7-2(isoform-parent)|ensembl:ENSG00000198945(gene)|ensembl:ENST00000368139(transcript)|ensembl:ENST00000526019(transcript)|ensembl:ENST00000533560(transcript)|intact:EBI-2686809(isoform-parent)|entrezgene/locuslink:84456(identity)	go:"GO:0008270"(zinc ion binding)|interpro:IPR000313(PWWP)|interpro:IPR011124(Zinc finger, CW-type)|interpro:IPR042778|entrezgene/locuslink:55063(identity)	intact:EBI-16429737(see-also)|intact:EBI-16429749(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:kyV/W+LGXQyvpNVA8XqVS88scjg9606	rogid:kd2aWGkvURF0tE0/nLpaz7LijXc9606	rigid:IbsqEGGpNVP7kelfNACKtxgAS+M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:A0A0S2Z564	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-16475127	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:a0a0s2z564_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475150	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|entrezgene/locuslink:27033(identity)	intact:EBI-16433779(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:dXjoGOAoXzVBI3tXnuT+/JmnJIM9606	rigid:TCjVm5G4ehiG2PWbM1wIXS89oFc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8ND90	uniprotkb:A0A0S2Z6P0	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	intact:EBI-16429989	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475485	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16429227(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:N/C6x8xI+eqpBTTZ0Rq/d14UIhQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:A0A0S2Z6P0	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-16429989	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476070	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16432394(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:rgDgdU4CKWdBP7IZcD3lve7pp0Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:A0A0S2Z6P0	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-16429989	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475541	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16429588(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:Ke0tNxslAf5HvHAmhu86mWKedok	true	sufficient binding region:21-705	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:A0A0S2Z6P0	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-16429989	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476038	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16432324(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:flMUDK2T89keoZpeHqsABAH6ECA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P0C7X2	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476022	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432324(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:VGjafZth0tz0qhwBEq3uyhHTUec	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P0C7X2	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476005	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432188(see-also)|intact:EBI-16432198(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:zt+Cd+Sd/TKTSyCodArGTl6Zato	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6NT76	uniprotkb:A0A0S2Z6P0	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	intact:EBI-16429989	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475989	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1|entrezgene/locuslink:79618(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16432078(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:fl+dfcxwO4iyM+RwRA197GEvfW0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6NT76	uniprotkb:P0C7X2	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475973	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1|entrezgene/locuslink:79618(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432078(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:o8mReh9jULlmd8ynRSpt5OF4fEw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P0C7X2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475953	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432034(see-also)|intact:EBI-16432046(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:Q6vQ35jSx5hOsBoj1ho5wRdaZqk	true	sufficient binding region:13-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H257-3	uniprotkb:A0A0S2Z6P0	intact:EBI-16431743|ensembl:ENSP00000451368	intact:EBI-16429989	psi-mi:q9h257-3(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475937	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000489932(transcript)|uniprotkb:Q9H257-3(isoform-parent)|entrezgene/locuslink:64170(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16431768(see-also)	isoform-comment:No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8ZrBhVHfPbIFpll5feiFDiUdyYs9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:i3vd8GNtaQve3GdAnon6OMv1ICw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H257-3	uniprotkb:P0C7X2	intact:EBI-16431743|ensembl:ENSP00000451368	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q9h257-3(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475921	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000489932(transcript)|uniprotkb:Q9H257-3(isoform-parent)|entrezgene/locuslink:64170(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16431768(see-also)	isoform-comment:No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8ZrBhVHfPbIFpll5feiFDiUdyYs9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:KchmooM8U5tY8LsmQlNnKxtKLd8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6NUQ1	uniprotkb:P0C7X2	intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475904	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N|entrezgene/locuslink:60561(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16431669(see-also)|intact:EBI-16431679(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:4/SghshfxNAL4xsGLS03RMul0iU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UL42	uniprotkb:A0A0S2Z6P0	intact:EBI-302355|uniprotkb:O94959|uniprotkb:O95145|uniprotkb:Q49A18|uniprotkb:Q9UL43|ensembl:ENSP00000429344|uniprotkb:B3KNY9	intact:EBI-16429989	psi-mi:pnma2_human(display_long)|uniprotkb:PNMA2(gene name)|psi-mi:PNMA2(display_short)|uniprotkb:KIAA0883(gene name synonym)|uniprotkb:MA2(gene name synonym)|uniprotkb:Onconeuronal antigen Ma2(gene name synonym)|uniprotkb:Paraneoplastic neuronal antigen MM2(gene name synonym)|uniprotkb:40 kDa neuronal protein(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475888	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009188.1|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026525|mint:Q9UL42|ensembl:ENSG00000240694(gene)|ensembl:ENST00000522362(transcript)|go:"GO:0005730"(nucleolus)|refseq:XP_011542667.1|entrezgene/locuslink:10687(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16431277(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GeMwoq69tYJJJc5lI0/bSAGlsCQ9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:zLYaqQvfwYpaWaekWC/G3CIPeC4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9UL42	uniprotkb:P0C7X2	intact:EBI-302355|uniprotkb:O94959|uniprotkb:O95145|uniprotkb:Q49A18|uniprotkb:Q9UL43|ensembl:ENSP00000429344|uniprotkb:B3KNY9	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:pnma2_human(display_long)|uniprotkb:PNMA2(gene name)|psi-mi:PNMA2(display_short)|uniprotkb:KIAA0883(gene name synonym)|uniprotkb:MA2(gene name synonym)|uniprotkb:Onconeuronal antigen Ma2(gene name synonym)|uniprotkb:Paraneoplastic neuronal antigen MM2(gene name synonym)|uniprotkb:40 kDa neuronal protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475872	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009188.1|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026525|mint:Q9UL42|ensembl:ENSG00000240694(gene)|ensembl:ENST00000522362(transcript)|go:"GO:0005730"(nucleolus)|refseq:XP_011542667.1|entrezgene/locuslink:10687(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16431277(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GeMwoq69tYJJJc5lI0/bSAGlsCQ9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:2nqrQQJspQh0TL/GPftu1VW6xz0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13064	uniprotkb:P0C7X2	intact:EBI-2340269|ensembl:ENSP00000313881	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475856	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064|entrezgene/locuslink:7681(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16431211(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:8E9WSXM0Q/gy1GONMK86aT6bsP0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P25788	uniprotkb:A0A0S2Z6P0	intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6	intact:EBI-16429989	psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475840	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N|entrezgene/locuslink:5684(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16431052(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:hzjmqAWpB+oZzYFunTdyg/Cr8ck	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P25788	uniprotkb:P0C7X2	intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475824	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N|entrezgene/locuslink:5684(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16431052(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:wGdY4FpDC58/zsuuw2uQ5u+NOic	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H2G9	uniprotkb:P0C7X2	intact:EBI-2548012|intact:EBI-28986503|ensembl:ENSP00000327541|ensembl:ENSP00000356782|uniprotkb:O15298|uniprotkb:Q5T531|uniprotkb:Q5T533|uniprotkb:Q9GZX4	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:go45_human(display_long)|uniprotkb:BLZF1(gene name)|psi-mi:BLZF1(display_short)|uniprotkb:JEM1(gene name synonym)|uniprotkb:Basic leucine zipper nuclear factor 1(gene name synonym)|uniprotkb:JEM-1(gene name synonym)|uniprotkb:p45 basic leucine-zipper nuclear factor(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475808	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508394.1|ensembl:ENSG00000117475(gene)|ensembl:ENST00000329281(transcript)|ensembl:ENST00000367808(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR013183(Protein of unknown function DUF1721, fungi)|interpro:IPR027095|mint:Q9H2G9|reactome:R-HSA-162658|refseq:NP_003657.1|ensembl:ENSP00000327541|ensembl:ENST00000367807|ensembl:ENSP00000356781|ensembl:ENSP00000356782|refseq:NP_001307901.1|refseq:NP_001307902.1|entrezgene/locuslink:8548(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16431032(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FqMAghbeSRbqLmtaKELM5JZ+H3s9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:uDGhrqK40w/fBOobCh1W8yjbGXQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:P0C7X2	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475775	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430803(see-also)|intact:EBI-16430813(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:l+HZW6vSyq/CXOgwcXjw+4B1BQo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13077	uniprotkb:P0C7X2	intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475792	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956|entrezgene/locuslink:7185(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430845(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:T0BvUp+TsPvdfaIv3PAgDcArVV4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:A0A0S2Z6P0	-	intact:EBI-16429989	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475759	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16430684(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:4wbmY9haTpGLGiF65PdGFILWjhE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16430628	uniprotkb:P0C7X2	-	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:"ccsb orf id: 12191"(display_short)|psi-mi:EBI-16430628(display_long)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475743	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:117178(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430684(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:cITdTpjhYrWVbcYmNy3ApoXa1jc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-10177480	uniprotkb:A0A0S2Z6P0	-	intact:EBI-16429989	psi-mi:clone_11897(display_short)|psi-mi:EBI-10177480(display_long)|uniprotkb:Cerebral protein 11(gene name synonym)|uniprotkb:KIAA0481(gene name synonym)|uniprotkb:hucep-11(orf name)|uniprotkb:TMCC2(gene name)|psi-mi:TMCC2(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475727	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:O75069-4(see-also)|intact:EBI-12696212(see-also)|intact:EBI-726731(see-also)|entrezgene/locuslink:9911(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16430492(see-also)	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/22	rogid:hIJ1KAUaIyjszZvvmcTXV6Nox8o9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:CGSWlgBvvWrDD/MkcjPa5hdEKCY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-10177480	uniprotkb:P0C7X2	-	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:clone_11897(display_short)|psi-mi:EBI-10177480(display_long)|uniprotkb:Cerebral protein 11(gene name synonym)|uniprotkb:KIAA0481(gene name synonym)|uniprotkb:hucep-11(orf name)|uniprotkb:TMCC2(gene name)|psi-mi:TMCC2(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475711	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:O75069-4(see-also)|intact:EBI-12696212(see-also)|intact:EBI-726731(see-also)|entrezgene/locuslink:9911(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430492(see-also)	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2020/06/22	rogid:hIJ1KAUaIyjszZvvmcTXV6Nox8o9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:k9xBdvcTuWhfoCM/f+IqfCtwVSI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99081-3	uniprotkb:A0A0S2Z5X4	intact:EBI-11952764|ensembl:ENSP00000331057|ensembl:ENSP00000388940	intact:EBI-16429014	psi-mi:q99081-3(display_long)|uniprotkb:TCF12(gene name)|psi-mi:TCF12(display_short)|uniprotkb:BHLHB20(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 20(gene name synonym)|uniprotkb:DNA-binding protein HTF4(gene name synonym)|uniprotkb:E-box-binding protein(gene name synonym)|uniprotkb:HEB(gene name synonym)|uniprotkb:HTF4(gene name synonym)|uniprotkb:Transcription factor HTF-4(gene name synonym)|uniprotkb:c(isoform synonym)	psi-mi:a0a0s2z5x4_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475695	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-722877(isoform-parent)|uniprotkb:Q99081-3(isoform-parent)|ensembl:ENSG00000140262(gene)|ensembl:ENST00000333725(transcript)|ensembl:ENST00000438423(transcript)|entrezgene/locuslink:6938(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|entrezgene/locuslink:146542(identity)	intact:EBI-16430405(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Sz84TChPfDPpa01k4znWJvWbQWU9606	rogid:amQX5Qvpa+WepWcjfBDWTIMjx+s9606	rigid:Ah2u0nterhlZNw+r4ahYcydVd1g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99081-3	uniprotkb:P0C7X2	intact:EBI-11952764|ensembl:ENSP00000331057|ensembl:ENSP00000388940	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q99081-3(display_long)|uniprotkb:TCF12(gene name)|psi-mi:TCF12(display_short)|uniprotkb:BHLHB20(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 20(gene name synonym)|uniprotkb:DNA-binding protein HTF4(gene name synonym)|uniprotkb:E-box-binding protein(gene name synonym)|uniprotkb:HEB(gene name synonym)|uniprotkb:HTF4(gene name synonym)|uniprotkb:Transcription factor HTF-4(gene name synonym)|uniprotkb:c(isoform synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475679	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-722877(isoform-parent)|uniprotkb:Q99081-3(isoform-parent)|ensembl:ENSG00000140262(gene)|ensembl:ENST00000333725(transcript)|ensembl:ENST00000438423(transcript)|entrezgene/locuslink:6938(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430405(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Sz84TChPfDPpa01k4znWJvWbQWU9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:I0iaNPLLKKRTgC5rBx2xBiX/3wA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VWX1	uniprotkb:A0A0S2Z6P0	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	intact:EBI-16429989	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475663	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468|entrezgene/locuslink:202559(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16430341(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:hEtwBrRwBgMRdH4hHxnZ03CUt7Q	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5VWX1	uniprotkb:P0C7X2	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475647	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468|entrezgene/locuslink:202559(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430341(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:HOx8CJU2bEk4EvY4N4ZuA2BB5jg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BVG8-5	uniprotkb:A0A0S2Z6P0	intact:EBI-14069005|ensembl:ENSP00000396399|ensembl:ENSP00000454659|ensembl:ENSP00000456239	intact:EBI-16429989	psi-mi:q9bvg8-5(display_long)|uniprotkb:KIFC3(gene name)|psi-mi:KIFC3(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475631	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2125614(isoform-parent)|uniprotkb:Q9BVG8-5(isoform-parent)|ensembl:ENSG00000140859(gene)|ensembl:ENST00000421376(transcript)|ensembl:ENST00000465878(transcript)|ensembl:ENST00000562903(transcript)|entrezgene/locuslink:3801(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16430207(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:0+/OISIWq43SLdciB0TI/JqsEUo9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:EugJlqVDotRHFcg2W7wEUSpjr5s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BVG8-5	uniprotkb:P0C7X2	intact:EBI-14069005|ensembl:ENSP00000396399|ensembl:ENSP00000454659|ensembl:ENSP00000456239	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q9bvg8-5(display_long)|uniprotkb:KIFC3(gene name)|psi-mi:KIFC3(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475615	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2125614(isoform-parent)|uniprotkb:Q9BVG8-5(isoform-parent)|ensembl:ENSG00000140859(gene)|ensembl:ENST00000421376(transcript)|ensembl:ENST00000465878(transcript)|ensembl:ENST00000562903(transcript)|entrezgene/locuslink:3801(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430207(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:0+/OISIWq43SLdciB0TI/JqsEUo9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:R00a+plrL+SLBzXjTjNF/pLhTJI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TD10	uniprotkb:A0A0S2Z6P0	intact:EBI-2548751|ensembl:ENSP00000333539|ensembl:ENSP00000379589|ensembl:ENSP00000444254|ensembl:ENSP00000506738|uniprotkb:Q7Z3J0|uniprotkb:Q8IV14|uniprotkb:D3DSA4	intact:EBI-16429989	psi-mi:mipo1_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475596	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151338(gene)|ensembl:ENST00000327441(transcript)|ensembl:ENST00000396294(transcript)|ensembl:ENST00000537471(transcript)|ensembl:ENST00000684589(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR026175|mint:Q8TD10|refseq:NP_001182225.1|refseq:NP_001182226.1|refseq:NP_620059.1|refseq:XP_016876492.1|refseq:XP_016876493.1|refseq:XP_016876494.1|entrezgene/locuslink:145282(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16430097(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:X4gY7nzDtnrS2yil7QhmLH968Ug9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:XVnx74tl2VYyKZ4yPL1knPdITfU	true	sufficient binding region:182-442	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8TD10	uniprotkb:P0C7X2	intact:EBI-2548751|ensembl:ENSP00000333539|ensembl:ENSP00000379589|ensembl:ENSP00000444254|ensembl:ENSP00000506738|uniprotkb:Q7Z3J0|uniprotkb:Q8IV14|uniprotkb:D3DSA4	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:mipo1_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475577	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151338(gene)|ensembl:ENST00000327441(transcript)|ensembl:ENST00000396294(transcript)|ensembl:ENST00000537471(transcript)|ensembl:ENST00000684589(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR026175|mint:Q8TD10|refseq:NP_001182225.1|refseq:NP_001182226.1|refseq:NP_620059.1|refseq:XP_016876492.1|refseq:XP_016876493.1|refseq:XP_016876494.1|entrezgene/locuslink:145282(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16430097(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:X4gY7nzDtnrS2yil7QhmLH968Ug9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:Xb4tmt4nlMWTvdG8dalXJU7xY3o	true	sufficient binding region:182-442	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P0C7X2	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16475560	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16429991(see-also)|intact:EBI-16430001(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:zt+Cd+Sd/TKTSyCodArGTl6Zato	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:P0C7X2	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476054	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432394(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:LkFVSjeY6uLv/OYA04FCAWk0Zr8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q5TD97	uniprotkb:P0C7X2	intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476118	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68|entrezgene/locuslink:9457(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432476(see-also)|intact:EBI-16432486(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:ZTNcIGu+3T43kPeJASd6dLO18Lw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9C0F1	uniprotkb:A0A0S2Z6P0	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	intact:EBI-16429989	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476102	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16432446(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:YWssy0Jqv+6UHsgD7n4hELdDUBg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9C0F1	uniprotkb:P0C7X2	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476086	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432446(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:KTK4s8ioGirDukR27WnKAkc5urs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BUZ4	uniprotkb:P0C7X2	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476355	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1|entrezgene/locuslink:9618(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16433576(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:b3tDKzmIWmhnNFRD+K5pnYIOFmw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00308	uniprotkb:A0A0S2Z6P0	intact:EBI-743923|uniprotkb:H3BRF3|uniprotkb:Q6ZTQ5|uniprotkb:A6NEP1|uniprotkb:Q96CZ2|uniprotkb:Q9BWN6|uniprotkb:B2R706|uniprotkb:B4DTL5|uniprotkb:F5H213|uniprotkb:I3RSG8|ensembl:ENSP00000352069	intact:EBI-16429989	psi-mi:wwp2_human(display_long)|uniprotkb:WW domain-containing protein 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 2(gene name synonym)|uniprotkb:WWP2(gene name)|psi-mi:WWP2(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase WWP2(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476339	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008945.2|refseq:NP_001257383.1|refseq:NP_001257384.1|refseq:XP_011521125.1|refseq:XP_011521127.1|refseq:XP_011521128.1|refseq:NP_001257382.1|refseq:NP_955456.1|refseq:XP_016878368.1|refseq:XP_016878369.1|refseq:XP_016878370.1|ensembl:ENSG00000198373(gene)|ensembl:ENST00000359154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006858"(extracellular transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051224"(negative regulation of protein transport)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:O00308|rcsb pdb:4Y07|rcsb pdb:5TJ7|rcsb pdb:5TJ8|rcsb pdb:5TJQ|rcsb pdb:6J1Z|rcsb pdb:6RSS|reactome:R-HSA-8948751|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013507|entrezgene/locuslink:11060(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16433496(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Xj0Xssn75HP9sp/tHNe4n83eHPE9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:jRoX2n7Mbh2ndU1Pa9Reeg1h34k	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O00308	uniprotkb:P0C7X2	intact:EBI-743923|uniprotkb:H3BRF3|uniprotkb:Q6ZTQ5|uniprotkb:A6NEP1|uniprotkb:Q96CZ2|uniprotkb:Q9BWN6|uniprotkb:B2R706|uniprotkb:B4DTL5|uniprotkb:F5H213|uniprotkb:I3RSG8|ensembl:ENSP00000352069	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:wwp2_human(display_long)|uniprotkb:WW domain-containing protein 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 2(gene name synonym)|uniprotkb:WWP2(gene name)|psi-mi:WWP2(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase WWP2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476323	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008945.2|refseq:NP_001257383.1|refseq:NP_001257384.1|refseq:XP_011521125.1|refseq:XP_011521127.1|refseq:XP_011521128.1|refseq:NP_001257382.1|refseq:NP_955456.1|refseq:XP_016878368.1|refseq:XP_016878369.1|refseq:XP_016878370.1|ensembl:ENSG00000198373(gene)|ensembl:ENST00000359154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006858"(extracellular transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051224"(negative regulation of protein transport)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:O00308|rcsb pdb:4Y07|rcsb pdb:5TJ7|rcsb pdb:5TJ8|rcsb pdb:5TJQ|rcsb pdb:6J1Z|rcsb pdb:6RSS|reactome:R-HSA-8948751|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013507|entrezgene/locuslink:11060(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16433496(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Xj0Xssn75HP9sp/tHNe4n83eHPE9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:5CCISQbZQ//OlFza0wPMKo39X8A	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:A0A0S2Z5X4	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-16429014	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:a0a0s2z5x4_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476307	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|entrezgene/locuslink:146542(identity)	intact:EBI-16433373(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:amQX5Qvpa+WepWcjfBDWTIMjx+s9606	rigid:QPWtG8mtDAMb8UTb+KXt33b2zis	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:P0C7X2	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476291	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16433373(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:A1ZgkSRFNjr4bIgAqc9yX3nYKHU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O43586	uniprotkb:P0C7X2	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476275	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|entrezgene/locuslink:9051(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16433167(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:hK/IxWTd2IWCIiNHCyJWHHTSOE8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:A0A0S2Z6P0	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-16429989	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476259	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16433137(see-also)	crc64:609B121DA1A9DCB8	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:Ow8Wv+fHTFOxrjD/XHDj66D+v6g	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:P0C7X2	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476243	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16433137(see-also)	crc64:609B121DA1A9DCB8	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:MAw+gpA0lm9atJBEEimpyKG5qy0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96KQ7	uniprotkb:A0A0S2Z6P0	intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957	intact:EBI-16429989	psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476224	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|entrezgene/locuslink:10919(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16432973(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:InmNGe5ecE4/MzcxWZdtX8Kk5BQ	true	sufficient binding region:210-1210	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96KQ7	uniprotkb:P0C7X2	intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476205	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|entrezgene/locuslink:10919(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432973(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:3jPCjDToxPCKN6oju6XA5RLLuxw	true	sufficient binding region:210-1210	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:A0A0S2Z6P0	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-16429989	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476186	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16432832(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:YKrZRPvBQPtzKXBx/HaiFIknZ2U	true	sufficient binding region:11-594	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:P0C7X2	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476167	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432832(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:q/LHZYbjm8Nk2ZKixm3WNRbW13c	true	sufficient binding region:11-594	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8HWS3	uniprotkb:A0A0S2Z6P0	intact:EBI-746118|uniprotkb:Q5T6B3|ensembl:ENSP00000332208	intact:EBI-16429989	psi-mi:rfx6_human(display_long)|uniprotkb:RFX6(gene name)|psi-mi:RFX6(display_short)|uniprotkb:RFXDC1(gene name synonym)|uniprotkb:Regulatory factor X 6(gene name synonym)|uniprotkb:Regulatory factor X domain-containing protein 1(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476151	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_775831.2|ensembl:ENSG00000185002(gene)|ensembl:ENST00000332958(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003311"(pancreatic D cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0090104"(pancreatic epsilon cell differentiation)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|reactome:R-HSA-210745|entrezgene/locuslink:222546(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16432756(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:R+QlHzmQeSg5ysiHPI4G8+NSYhE9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:zucX9mNZ1DLFnMMhTONa4D4z424	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8HWS3	uniprotkb:P0C7X2	intact:EBI-746118|uniprotkb:Q5T6B3|ensembl:ENSP00000332208	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:rfx6_human(display_long)|uniprotkb:RFX6(gene name)|psi-mi:RFX6(display_short)|uniprotkb:RFXDC1(gene name synonym)|uniprotkb:Regulatory factor X 6(gene name synonym)|uniprotkb:Regulatory factor X domain-containing protein 1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476135	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_775831.2|ensembl:ENSG00000185002(gene)|ensembl:ENST00000332958(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003311"(pancreatic D cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0090104"(pancreatic epsilon cell differentiation)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|reactome:R-HSA-210745|entrezgene/locuslink:222546(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16432756(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:R+QlHzmQeSg5ysiHPI4G8+NSYhE9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:nuxUn8iRe6JuWcR6omqlz7J4U5M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H257-2	uniprotkb:P0C7X2	intact:EBI-11530605|ensembl:ENSP00000360799	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q9h257-2(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476784	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|uniprotkb:Q9H257-2(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000371734(transcript)|entrezgene/locuslink:64170(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16435972(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZXH7B3K5NAzF1LZaeK50ciH1RTE9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:qW1oJ40QhcW5KgpcASLmqoB7ZNY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:P0C7X2	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476400	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16433633(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:cIJG+vN56IGKvufmyqZB9RmhJQU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:A0A0S2Z6P0	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-16429989	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476416	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16433633(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:XH3NHdAwFxuQPZudHw1lJZ2Jd/M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15654	uniprotkb:P0C7X2	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476432	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16433971(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:vyxSQmZH8l1nomX53OAlZ8vo7Oo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:A2RRN7	uniprotkb:P0C7X2	intact:EBI-10179719|intact:EBI-12002280|intact:EBI-12753183	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:a2rrn7_human(display_long)|uniprotkb:CADPS(gene name)|psi-mi:CADPS(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477112	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR033227|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014770(Munc13 homology 1)|go:"GO:0015031"(protein transport)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0098793"(presynapse)|go:"GO:1990504"(dense core granule exocytosis)|entrezgene/locuslink:8618(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16437185(see-also)|intact:EBI-16437195(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:N5Akbv6I+Z6ng6fGGng679DVg9U9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:3L6u/BQOBN01TD0uSXsVXD4To1I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16437007	uniprotkb:A0A0S2Z6P0	-	intact:EBI-16429989	psi-mi:"ccsb orf id: 56711"(display_short)|psi-mi:EBI-16437007(display_long)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477096	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:386682(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16437099(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TyoW1FiRm0mclGU0YkO2RWsRGo9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:tC1rxWIvqfufMI2CCOW3asbBtfA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16437007	uniprotkb:P0C7X2	-	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:"ccsb orf id: 56711"(display_short)|psi-mi:EBI-16437007(display_long)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477080	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:386682(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16437099(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:+TyoW1FiRm0mclGU0YkO2RWsRGo9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:Rj51Sm51x1jb4F/OwhBCPjO7tf0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P15884-3	uniprotkb:P0C7X2	intact:EBI-13636688|ensembl:ENSP00000346440|ensembl:ENSP00000486670	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:p15884-3(display_long)|uniprotkb:Class B basic helix-loop-helix protein 19(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:B+(isoform synonym)|uniprotkb:TCF4(gene name)|psi-mi:TCF4(display_short)|uniprotkb:BHLHB19(gene name synonym)|uniprotkb:ITF2(gene name synonym)|uniprotkb:SEF2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477063	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-533224(isoform-parent)|ensembl:ENSG00000196628(gene)|ensembl:ENST00000354452(transcript)|ensembl:ENST00000629387(transcript)|uniprotkb:P15884-3(isoform-parent)|entrezgene/locuslink:6925(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436901(see-also)|intact:EBI-16436911(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZNbTMfCK9F8zDtvfNHuHnQpJM7w9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:TuXBhajKajlEwZ0fAKz48OuXZF8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P60411	uniprotkb:A0A0S2Z6P0	intact:EBI-10172052|uniprotkb:A2RRG1|uniprotkb:Q70LJ1|uniprotkb:A6NIR9|ensembl:ENSP00000381009	intact:EBI-16429989	psi-mi:kr109_human(display_long)|uniprotkb:KRTAP10-9(gene name)|psi-mi:KRTAP10-9(display_short)|uniprotkb:High sulfur keratin-associated protein 10.9(gene name synonym)|uniprotkb:KAP10.9(gene name synonym)|uniprotkb:KAP18-9(gene name synonym)|uniprotkb:KRTAP10.9(gene name synonym)|uniprotkb:KRTAP18-9(gene name synonym)|uniprotkb:KRTAP18.9(gene name synonym)|uniprotkb:Keratin-associated protein 10.9(gene name synonym)|uniprotkb:Keratin-associated protein 18-9(gene name synonym)|uniprotkb:Keratin-associated protein 18.9(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477047	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_941963.2|ensembl:ENSG00000221837(gene)|ensembl:ENST00000397911(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|reactome:R-HSA-6805567|refseq:NP_941965.2|entrezgene/locuslink:386676(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16436841(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Nh6MH4M6TUhmqNrV+Oj14IwKk389606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:txRtkDQ8Sh0q3cx5p85pywUnXc8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P60411	uniprotkb:P0C7X2	intact:EBI-10172052|uniprotkb:A2RRG1|uniprotkb:Q70LJ1|uniprotkb:A6NIR9|ensembl:ENSP00000381009	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:kr109_human(display_long)|uniprotkb:KRTAP10-9(gene name)|psi-mi:KRTAP10-9(display_short)|uniprotkb:High sulfur keratin-associated protein 10.9(gene name synonym)|uniprotkb:KAP10.9(gene name synonym)|uniprotkb:KAP18-9(gene name synonym)|uniprotkb:KRTAP10.9(gene name synonym)|uniprotkb:KRTAP18-9(gene name synonym)|uniprotkb:KRTAP18.9(gene name synonym)|uniprotkb:Keratin-associated protein 10.9(gene name synonym)|uniprotkb:Keratin-associated protein 18-9(gene name synonym)|uniprotkb:Keratin-associated protein 18.9(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477031	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_941963.2|ensembl:ENSG00000221837(gene)|ensembl:ENST00000397911(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|reactome:R-HSA-6805567|refseq:NP_941965.2|entrezgene/locuslink:386676(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436841(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Nh6MH4M6TUhmqNrV+Oj14IwKk389606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:eeu43XxUpcpxMrVS7hCrcf007uM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P59991	uniprotkb:A0A0S2Z6P0	intact:EBI-10176379|uniprotkb:Q0VAS4|uniprotkb:A6NIS1|uniprotkb:A6NMS9|ensembl:ENSP00000354001	intact:EBI-16429989	psi-mi:kr122_human(display_long)|uniprotkb:KRTAP12-2(gene name)|psi-mi:KRTAP12-2(display_short)|uniprotkb:High sulfur keratin-associated protein 12.2(gene name synonym)|uniprotkb:KAP12.2(gene name synonym)|uniprotkb:KRTAP12.2(gene name synonym)|uniprotkb:Keratin-associated protein 12.2(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477015	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_859012.1|ensembl:ENSG00000221864(gene)|ensembl:ENST00000360770(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567|entrezgene/locuslink:353323(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16436757(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:No3kGE8TWTn4MyHaXXBiGmc5LIk9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:y84+U58Mka0QoBejo9AkkeuTB+c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P59991	uniprotkb:P0C7X2	intact:EBI-10176379|uniprotkb:Q0VAS4|uniprotkb:A6NIS1|uniprotkb:A6NMS9|ensembl:ENSP00000354001	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:kr122_human(display_long)|uniprotkb:KRTAP12-2(gene name)|psi-mi:KRTAP12-2(display_short)|uniprotkb:High sulfur keratin-associated protein 12.2(gene name synonym)|uniprotkb:KAP12.2(gene name synonym)|uniprotkb:KRTAP12.2(gene name synonym)|uniprotkb:Keratin-associated protein 12.2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476999	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_859012.1|ensembl:ENSG00000221864(gene)|ensembl:ENST00000360770(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567|entrezgene/locuslink:353323(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436757(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:No3kGE8TWTn4MyHaXXBiGmc5LIk9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:7aBfaFtYmsN3f4d+Vuf3Lbwi+NY	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q63HR2	uniprotkb:A0A0S2Z6P0	intact:EBI-949753|ensembl:ENSP00000319684|uniprotkb:A2VDF2|uniprotkb:A2VDF3|uniprotkb:A2VDI8|uniprotkb:Q2NL80|uniprotkb:Q76MW6|uniprotkb:Q7Z5T9|uniprotkb:Q8NFF9|uniprotkb:Q8NFG0|uniprotkb:Q96P25|uniprotkb:Q9NT29|uniprotkb:Q9UPS7|uniprotkb:A5PKY4	intact:EBI-16429989	psi-mi:tns2_human(display_long)|uniprotkb:TNS2(gene name)|psi-mi:TNS2(display_short)|uniprotkb:C1 domain-containing phosphatase and tensin homolog(gene name synonym)|uniprotkb:KIAA1075(gene name synonym)|uniprotkb:TENC1(gene name synonym)|uniprotkb:Tensin-like C1 domain-containing phosphatase(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476980	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000314250(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014850"(response to muscle activity)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0019900"(kinase binding)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048871"(multicellular organismal homeostasis)|interpro:IPR000980(SH2 motif)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|interpro:IPR029023|interpro:IPR033929|interpro:IPR035012|interpro:IPR035892|interpro:IPR036860|mint:Q63HR2|rcsb pdb:2DKQ|rcsb pdb:2KNO|rcsb pdb:2L6K|rcsb pdb:2LOZ|rcsb pdb:3HQC|ensembl:ENSG00000111077(gene)|refseq:NP_056134.2|refseq:NP_736610.2|refseq:NP_938072.1|entrezgene/locuslink:23371(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16436705(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:uobqTi6g78V5Iib3uRGGhqjSt7o9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:jXQO23obzinqUYhUBOAwC/gtENk	true	sufficient binding region:125-1409	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q63HR2	uniprotkb:P0C7X2	intact:EBI-949753|ensembl:ENSP00000319684|uniprotkb:A2VDF2|uniprotkb:A2VDF3|uniprotkb:A2VDI8|uniprotkb:Q2NL80|uniprotkb:Q76MW6|uniprotkb:Q7Z5T9|uniprotkb:Q8NFF9|uniprotkb:Q8NFG0|uniprotkb:Q96P25|uniprotkb:Q9NT29|uniprotkb:Q9UPS7|uniprotkb:A5PKY4	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:tns2_human(display_long)|uniprotkb:TNS2(gene name)|psi-mi:TNS2(display_short)|uniprotkb:C1 domain-containing phosphatase and tensin homolog(gene name synonym)|uniprotkb:KIAA1075(gene name synonym)|uniprotkb:TENC1(gene name synonym)|uniprotkb:Tensin-like C1 domain-containing phosphatase(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476961	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000314250(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014850"(response to muscle activity)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0019900"(kinase binding)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048871"(multicellular organismal homeostasis)|interpro:IPR000980(SH2 motif)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|interpro:IPR029023|interpro:IPR033929|interpro:IPR035012|interpro:IPR035892|interpro:IPR036860|mint:Q63HR2|rcsb pdb:2DKQ|rcsb pdb:2KNO|rcsb pdb:2L6K|rcsb pdb:2LOZ|rcsb pdb:3HQC|ensembl:ENSG00000111077(gene)|refseq:NP_056134.2|refseq:NP_736610.2|refseq:NP_938072.1|entrezgene/locuslink:23371(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436705(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:uobqTi6g78V5Iib3uRGGhqjSt7o9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:9qsWCUZQggcDE5GSjc6Jr42XbmM	true	sufficient binding region:125-1409	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15323	uniprotkb:P0C7X2	intact:EBI-948001|uniprotkb:Q9UE12|ensembl:ENSP00000251645|ensembl:ENSP00000460739	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:k1h1_human(display_long)|uniprotkb:Hair keratin, type I Ha1(gene name synonym)|uniprotkb:Keratin-31(gene name synonym)|uniprotkb:KRT31(gene name)|psi-mi:KRT31(display_short)|uniprotkb:HHA1(gene name synonym)|uniprotkb:HKA1(gene name synonym)|uniprotkb:KRTHA1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476944	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002268.2|ensembl:ENSG00000094796(gene)|ensembl:ENSG00000262993(gene)|ensembl:ENST00000251645(transcript)|ensembl:ENST00000573281(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3881(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436625(see-also)|intact:EBI-16436635(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ur97LEvtqaqu3wh7iaX4HhN163k9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:wN8CXYYsHSn5nNZJiYKdUbfd5Hw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYR5	uniprotkb:A0A0S2Z6P0	intact:EBI-10172511|uniprotkb:A0JP64|ensembl:ENSP00000366955	intact:EBI-16429989	psi-mi:kra42_human(display_long)|uniprotkb:KRTAP4-2(gene name)|psi-mi:KRTAP4-2(display_short)|uniprotkb:KAP4.2(gene name synonym)|uniprotkb:KRTAP4.2(gene name synonym)|uniprotkb:Keratin-associated protein 4.2(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.2(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476928	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149051.1|ensembl:ENSG00000244537(gene)|ensembl:ENST00000377726(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|reactome:R-HSA-6805567|entrezgene/locuslink:85291(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16436595(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8Ecqy++IpYBBxTj/kQBOfnGxoiM9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:ePjNApUmS5w/hVmBBaokNkT3mMs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BYR5	uniprotkb:P0C7X2	intact:EBI-10172511|uniprotkb:A0JP64|ensembl:ENSP00000366955	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:kra42_human(display_long)|uniprotkb:KRTAP4-2(gene name)|psi-mi:KRTAP4-2(display_short)|uniprotkb:KAP4.2(gene name synonym)|uniprotkb:KRTAP4.2(gene name synonym)|uniprotkb:Keratin-associated protein 4.2(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476912	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149051.1|ensembl:ENSG00000244537(gene)|ensembl:ENST00000377726(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|reactome:R-HSA-6805567|entrezgene/locuslink:85291(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436595(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:8Ecqy++IpYBBxTj/kQBOfnGxoiM9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:3ZlUWoa3t9ay5DCVia0zxqhcmWk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:A0A0C3SFZ9	uniprotkb:A0A0S2Z6P0	intact:EBI-11977403|ensembl:ENSP00000473001	intact:EBI-16429989	psi-mi:a0a0c3sfz9_human(display_long)|uniprotkb:FCHO1(gene name)|psi-mi:FCHO1(display_short)|uniprotkb:hCG_2000568(orf name)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476896	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000130475(gene)|ensembl:ENST00000594202(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|interpro:IPR030121|interpro:IPR031160|interpro:IPR042735|go:"GO:0005829"(cytosol)|refseq:NP_001154829.1|entrezgene/locuslink:23149(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16436458(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:YfVbZHntDpLjsmnH0GM2eaqEGjY9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:FfE0QV0usCjiDfoltzZdBvHfs6I	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:A0A0C3SFZ9	uniprotkb:P0C7X2	intact:EBI-11977403|ensembl:ENSP00000473001	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:a0a0c3sfz9_human(display_long)|uniprotkb:FCHO1(gene name)|psi-mi:FCHO1(display_short)|uniprotkb:hCG_2000568(orf name)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476880	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000130475(gene)|ensembl:ENST00000594202(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|interpro:IPR030121|interpro:IPR031160|interpro:IPR042735|go:"GO:0005829"(cytosol)|refseq:NP_001154829.1|entrezgene/locuslink:23149(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436458(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:YfVbZHntDpLjsmnH0GM2eaqEGjY9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:Kt7CK+ltILCt5uiP2wV9EUEd6Eg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z3S9	uniprotkb:A0A0S2Z6P0	intact:EBI-945833|intact:EBI-2859688|uniprotkb:Q5BKT8|uniprotkb:Q5VTG9|uniprotkb:Q5XG84|uniprotkb:Q6P192|uniprotkb:Q8NC23|uniprotkb:Q8WUQ9|uniprotkb:Q96FY1|ensembl:ENSP00000354929	intact:EBI-16429989	psi-mi:nt2na_human(display_long)|uniprotkb:NOTCH2NLA(gene name)|psi-mi:NOTCH2NLA(display_short)|uniprotkb:N2N(gene name synonym)|uniprotkb:NOTCH2NL(gene name synonym)|uniprotkb:Notch homolog 2 N-terminal-like protein(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476864	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_982283.2|refseq:XP_016855384.1|refseq:XP_016855385.1|refseq:XP_016855386.1|refseq:XP_016855387.1|refseq:XP_016858537.1|refseq:XP_016858538.1|refseq:XP_016858539.1|refseq:XP_016858540.1|dip:DIP-47315N|refseq:XP_006711766.1|refseq:XP_006726418.1|ensembl:ENSG00000264343(gene)|ensembl:ENST00000362074(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|mint:Q7Z3S9|entrezgene/locuslink:388677(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16436368(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FYOai/KkVz8zMsxjNnyZ6FNfcTU9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:IdzTEBf5+nD10VTZVl4gAXXQy/Y	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7Z3S9	uniprotkb:P0C7X2	intact:EBI-945833|intact:EBI-2859688|uniprotkb:Q5BKT8|uniprotkb:Q5VTG9|uniprotkb:Q5XG84|uniprotkb:Q6P192|uniprotkb:Q8NC23|uniprotkb:Q8WUQ9|uniprotkb:Q96FY1|ensembl:ENSP00000354929	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:nt2na_human(display_long)|uniprotkb:NOTCH2NLA(gene name)|psi-mi:NOTCH2NLA(display_short)|uniprotkb:N2N(gene name synonym)|uniprotkb:NOTCH2NL(gene name synonym)|uniprotkb:Notch homolog 2 N-terminal-like protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476848	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_982283.2|refseq:XP_016855384.1|refseq:XP_016855385.1|refseq:XP_016855386.1|refseq:XP_016855387.1|refseq:XP_016858537.1|refseq:XP_016858538.1|refseq:XP_016858539.1|refseq:XP_016858540.1|dip:DIP-47315N|refseq:XP_006711766.1|refseq:XP_006726418.1|ensembl:ENSG00000264343(gene)|ensembl:ENST00000362074(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|mint:Q7Z3S9|entrezgene/locuslink:388677(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436368(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FYOai/KkVz8zMsxjNnyZ6FNfcTU9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:NrGsIS6oMvf2aYZLC7jt2dfq+3c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16436244	uniprotkb:P0C7X2	-	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:"ccsb orf id: 54692"(display_short)|psi-mi:EBI-16436244(display_long)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476832	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:57594(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436298(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:pQLRUATtfhRxD9ugVFmKu+SJGB89606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:mh/NGgpgao9T98FXX6UkVbfhel0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q6A162	uniprotkb:P0C7X2	intact:EBI-10171697|uniprotkb:Q6IFU5|ensembl:ENSP00000366984|ensembl:ENSP00000381500|ensembl:ENSP00000459621|ensembl:ENSP00000479080|ensembl:ENSP00000506768	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:k1c40_human(display_long)|uniprotkb:KRT40(gene name)|psi-mi:KRT40(display_short)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:KA36(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476816	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872303.2|ensembl:ENSG00000204889(gene)|ensembl:ENSG00000262845(gene)|ensembl:ENST00000377755(transcript)|ensembl:ENST00000398486(transcript)|ensembl:ENST00000576967(transcript)|ensembl:ENST00000610983(transcript)|ensembl:ENST00000684280(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:125115(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16436224(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:93lmDGFUau1S1lpef2rBMQpkkOA9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:SOBH7IjCC5Y3wO3BbsNut37uQ9s	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9H257-2	uniprotkb:A0A0S2Z6P0	intact:EBI-11530605|ensembl:ENSP00000360799	intact:EBI-16429989	psi-mi:q9h257-2(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476800	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|uniprotkb:Q9H257-2(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000371734(transcript)|entrezgene/locuslink:64170(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16435972(see-also)	isoform-comment:No experimental confirmation available.	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ZXH7B3K5NAzF1LZaeK50ciH1RTE9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:XAFfqfxiU0tIgTccebE4AYcg2m8	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9BUZ4	uniprotkb:A0A0S2Z6P0	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	intact:EBI-16429989	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476384	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1|entrezgene/locuslink:9618(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16433576(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:VsaqY3aJ9KVOei9PsSePvhAQD7M	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P13646	uniprotkb:P0C7X2	intact:EBI-1223876|uniprotkb:Q53G54|uniprotkb:Q6AZK5|uniprotkb:Q8N240|ensembl:ENSP00000246635	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:k1c13_human(display_long)|uniprotkb:KRT13(gene name)|psi-mi:KRT13(display_short)|uniprotkb:Keratin-13(gene name synonym)|uniprotkb:Cytokeratin-13(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476768	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002265.2|refseq:NP_705694.2|ensembl:ENSG00000171401(gene)|ensembl:ENST00000246635(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3860(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16435942(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:u65zix/f6VQ+vmbfMhXWqmiERRY9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:nwBAtGil8HP8t+0mN+IGpRTyBB4	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16435328	uniprotkb:A0A0S2Z6P0	-	intact:EBI-16429989	psi-mi:"ccsb orf id: 52859"(display_short)|psi-mi:EBI-16435328(display_long)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476752	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:64753(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16435360(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FWTUx0ZMr4g1buyVnmwu2LBoxaU9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:s1z0l/6danZtuf0i7ju31YfUexI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16435328	uniprotkb:P0C7X2	-	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:"ccsb orf id: 52859"(display_short)|psi-mi:EBI-16435328(display_long)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476736	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:64753(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16435360(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FWTUx0ZMr4g1buyVnmwu2LBoxaU9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:rrvFm9J4EO0cnnTkV/Hcd6j94eo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q7L4P6	uniprotkb:P0C7X2	intact:EBI-724373|ensembl:ENSP00000360899|uniprotkb:D3DQ27|uniprotkb:Q96A62|uniprotkb:Q9HAI3|intact:EBI-3044085	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:bend5_human(display_long)|uniprotkb:BEND5(gene name)|psi-mi:BEND5(display_short)|uniprotkb:C1orf165(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476720	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078879.2|ensembl:ENSG00000162373(gene)|ensembl:ENST00000371833(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR018379|interpro:IPR040391|mint:Q7L4P6|refseq:NP_001289011.1|refseq:XP_011540444.1|refseq:XP_016857823.1|entrezgene/locuslink:79656(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16435234(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:R6OwgNU76FX6tqLRdHVmzEgK8EE9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:+PX85qwwZmmTrA2a+gl6dlMUOqo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:A0A0S2Z6P0	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-16429989	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476704	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16435204(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:h5z7rIqXNdf+bribtgzjbSQliqA	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:P0C7X2	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476688	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16435204(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:rmcgY77p9F5FpfsQ5m61pbbhtQo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61457	uniprotkb:A0A0S2Z6P0	intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930	intact:EBI-16429989	psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476672	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16434965(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:GhdzrvjxQ8rgdat+QclPPnhwTZg	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61457	uniprotkb:P0C7X2	intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476656	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434965(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:K2alx7GmGgdoSQW3QINW5teW+bw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978-2	uniprotkb:P0C7X2	intact:EBI-7060731|ensembl:ENSP00000365439|ensembl:ENSP00000365458|uniprotkb:Q07244-2|intact:MINT-225449	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:p61978-2(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476640	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|ensembl:ENST00000376263(transcript)|ensembl:ENST00000376281(transcript)|intact:EBI-304185(isoform-parent)|uniprotkb:P61978-2(isoform-parent)|entrezgene/locuslink:3190(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434798(see-also)	comment:mint	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:FX/iS2YfOhD0ntY2oqpOUetACqg9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:1IoMiuFRC9b7n4FJYsPSlBWI4Os	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96IJ6	uniprotkb:A0A0S2Z5X4	intact:EBI-750953|uniprotkb:A6NJ74|uniprotkb:A8K3Q6|uniprotkb:Q53GI0|uniprotkb:Q9NWC3|uniprotkb:Q9Y5P5|uniprotkb:B3KMT4|ensembl:ENSP00000315925|ensembl:ENSP00000340760|ensembl:ENSP00000350949|ensembl:ENSP00000363016|ensembl:ENSP00000478700|ensembl:ENSP00000506941	intact:EBI-16429014	psi-mi:gmppa_human(display_long)|uniprotkb:GMPPA(gene name)|psi-mi:GMPPA(display_short)|uniprotkb:GTP-mannose-1-phosphate guanylyltransferase alpha(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase A(gene name synonym)	psi-mi:a0a0s2z5x4_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476624	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037467.2|refseq:NP_995319.1|refseq:XP_005246543.1|refseq:XP_016859398.1|refseq:XP_016859399.1|refseq:XP_016859400.1|ensembl:ENSG00000144591(gene)|ensembl:ENST00000313597(transcript)|ensembl:ENST00000341142(transcript)|ensembl:ENST00000358215(transcript)|ensembl:ENST00000373908(transcript)|ensembl:ENST00000622191(transcript)|ensembl:ENST00000683946(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|mint:Q96IJ6|rcsb pdb:7D72|rcsb pdb:7D73|rcsb pdb:7D74|reactome:R-HSA-446205|entrezgene/locuslink:29926(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|entrezgene/locuslink:146542(identity)	intact:EBI-16434579(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ASWzJoQB8W+e2OKYEenXpUJxflI9606	rogid:amQX5Qvpa+WepWcjfBDWTIMjx+s9606	rigid:6EqiMiHgeiTW2hjizeeOqornido	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96IJ6	uniprotkb:P0C7X2	intact:EBI-750953|uniprotkb:A6NJ74|uniprotkb:A8K3Q6|uniprotkb:Q53GI0|uniprotkb:Q9NWC3|uniprotkb:Q9Y5P5|uniprotkb:B3KMT4|ensembl:ENSP00000315925|ensembl:ENSP00000340760|ensembl:ENSP00000350949|ensembl:ENSP00000363016|ensembl:ENSP00000478700|ensembl:ENSP00000506941	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:gmppa_human(display_long)|uniprotkb:GMPPA(gene name)|psi-mi:GMPPA(display_short)|uniprotkb:GTP-mannose-1-phosphate guanylyltransferase alpha(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase A(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476608	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037467.2|refseq:NP_995319.1|refseq:XP_005246543.1|refseq:XP_016859398.1|refseq:XP_016859399.1|refseq:XP_016859400.1|ensembl:ENSG00000144591(gene)|ensembl:ENST00000313597(transcript)|ensembl:ENST00000341142(transcript)|ensembl:ENST00000358215(transcript)|ensembl:ENST00000373908(transcript)|ensembl:ENST00000622191(transcript)|ensembl:ENST00000683946(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|mint:Q96IJ6|rcsb pdb:7D72|rcsb pdb:7D73|rcsb pdb:7D74|reactome:R-HSA-446205|entrezgene/locuslink:29926(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434579(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:ASWzJoQB8W+e2OKYEenXpUJxflI9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:FcKoOUU3Hb8rKBvBGhuM85J4bK0	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NQZ6	uniprotkb:P0C7X2	intact:EBI-747993|uniprotkb:Q5JTF9|uniprotkb:Q9H9C3|uniprotkb:Q9H9H7|uniprotkb:Q9ULQ4|uniprotkb:B2RDC2|uniprotkb:B4DED0|uniprotkb:E7EM74|uniprotkb:B3KVZ5|uniprotkb:G3V1L3|uniprotkb:Q53H73|ensembl:ENSP00000363972	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:zc4h2_human(display_long)|uniprotkb:ZC4H2(gene name)|psi-mi:ZC4H2(display_short)|uniprotkb:KIAA1166(gene name synonym)|uniprotkb:HCA127(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 127(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476592	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171503.1|refseq:NP_061154.1|refseq:NP_001230733.1|refseq:NP_001171504.1|ensembl:ENSG00000126970(gene)|ensembl:ENST00000374839(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR018482|interpro:IPR044069|entrezgene/locuslink:55906(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434453(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:lQr6Z1Cs3RuhckvFry86sAyycBE9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:2qN6drLUEjFlAgq2Fpq3APaZqHw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15654	uniprotkb:A0A0S2Z6P0	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	intact:EBI-16429989	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476576	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16434443(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:eLDSTWw0N2lP8Yu14kKBGu8cles	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15654	uniprotkb:P0C7X2	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476560	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434443(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:vyxSQmZH8l1nomX53OAlZ8vo7Oo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:A0A0S2Z6P0	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-16429989	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476544	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16434327(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:2K/3rD3Eplvwqs+g+pTYt+RF4hM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P0C7X2	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476528	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434327(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:oOX8OE9qQ8E7HaXkJrl/zimTAvI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9P209	uniprotkb:A0A0S2Z6P0	intact:EBI-739498|uniprotkb:Q9BV03|uniprotkb:Q9BWM3|uniprotkb:Q9NVR4|uniprotkb:B4DR26|ensembl:ENSP00000264935	intact:EBI-16429989	psi-mi:cep72_human(display_long)|uniprotkb:CEP72(gene name)|psi-mi:CEP72(display_short)|uniprotkb:KIAA1519(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476512	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060610.2|ensembl:ENSG00000112877(gene)|ensembl:ENST00000264935(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0033566"(gamma-tubulin complex localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:1904779"(regulation of protein localization to centrosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR040146|mint:Q9P209|reactome:R-HSA-2565942|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|refseq:XP_011512365.1|dip:DIP-54272N|entrezgene/locuslink:55722(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16434170(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:c00WdgE2iudiQUz3kXNZL5d0nuQ9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:16uA93uouFfVYDws8Qr4YPXbfKs	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9P209	uniprotkb:P0C7X2	intact:EBI-739498|uniprotkb:Q9BV03|uniprotkb:Q9BWM3|uniprotkb:Q9NVR4|uniprotkb:B4DR26|ensembl:ENSP00000264935	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:cep72_human(display_long)|uniprotkb:CEP72(gene name)|psi-mi:CEP72(display_short)|uniprotkb:KIAA1519(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476496	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060610.2|ensembl:ENSG00000112877(gene)|ensembl:ENST00000264935(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0033566"(gamma-tubulin complex localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:1904779"(regulation of protein localization to centrosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR040146|mint:Q9P209|reactome:R-HSA-2565942|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|refseq:XP_011512365.1|dip:DIP-54272N|entrezgene/locuslink:55722(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434170(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:c00WdgE2iudiQUz3kXNZL5d0nuQ9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:1QtWoRNWUzLGcuL2k/sILgRyaUM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96R06	uniprotkb:A0A0S2Z6P0	intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300	intact:EBI-16429989	psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476480	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N|entrezgene/locuslink:10615(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16434160(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:Ydkc93ODUO3H1cXfizUyKtDyQDc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96R06	uniprotkb:P0C7X2	intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476464	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N|entrezgene/locuslink:10615(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16434160(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:6WFNPDQhXctyR5/nAricutmgofc	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q15654	uniprotkb:A0A0S2Z6P0	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	intact:EBI-16429989	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16476448	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16433971(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:eLDSTWw0N2lP8Yu14kKBGu8cles	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478	uniprotkb:P0C7X2	intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477129	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16438091(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:NeA5Bhr8f7g12DW1wO7ZFWRhqoo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:O75478	uniprotkb:A0A0S2Z6P0	intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016	intact:EBI-16429989	psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477145	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16438091(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:7l6zAgauzuru4ydPeS/6aR2ibTo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P0C7X2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477161	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16438674(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:Q6vQ35jSx5hOsBoj1ho5wRdaZqk	true	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:P0C7X2	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477180	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16438726(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:pTKXz4eljW6tWkORjUMcjh45XbE	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978	uniprotkb:P0C7X2	intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477225	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N|entrezgene/locuslink:3190(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16438870(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:dYkYWT4q876ZLYSXiTx6UWw/y0U	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:P61978	uniprotkb:A0A0S2Z6P0	intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1	intact:EBI-16429989	psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477241	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N|entrezgene/locuslink:3190(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16438870(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:fYS0vFFT6sY7eIA0xtMJWiVhTbM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:P0C7X2	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477257	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16439859(see-also)|intact:EBI-16439869(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:368jHYgp+2WnbT2Vgm8V0kRse58	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
intact:EBI-16439879	uniprotkb:P0C7X2	-	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:"ccsb orf id: 8359"(display_short)|psi-mi:EBI-16439879(display_long)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477274	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:80125(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16439913(see-also)|intact:EBI-16439923(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:poddy6+Qr+z8s1U2xyFnXJ05O6Y9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:SjA8oAebTiqkQOA72Zv4uE/G3Qw	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:A0A0S2Z6P0	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-16429989	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477209	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16438726(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:8PYvyU0aZ//Lc9FgVXGORn9LI0w	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q2TAC2-2	uniprotkb:P0C7X2	intact:EBI-10961624|ensembl:ENSP00000376154	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q2tac2-2(display_long)|uniprotkb:CCDC57(gene name)|psi-mi:CCDC57(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477323	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000176155(gene)|ensembl:ENST00000392343(transcript)|uniprotkb:Q2TAC2-2(isoform-parent)|intact:EBI-2808286(isoform-parent)|entrezgene/locuslink:284001(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16440256(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:RWcF0hgb1geIY959JUKrLK13Jx09606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:jRgMz45OsmRxhwuw0jwjsnCKgJk	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96D09	uniprotkb:P0C7X2	intact:EBI-473189|ensembl:ENSP00000339057|ensembl:ENSP00000437394|ensembl:ENSP00000437872|ensembl:ENSP00000507692|ensembl:ENSP00000508139|uniprotkb:Q8NAB4|uniprotkb:D3DXA0	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:gasp2_human(display_long)|uniprotkb:GPRASP2(gene name)|psi-mi:GPRASP2(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477291	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000158301(gene)|ensembl:ENST00000332262(transcript)|ensembl:ENST00000483720(transcript)|ensembl:ENST00000486814(transcript)|ensembl:ENST00000535209(transcript)|ensembl:ENST00000543253(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:NP_001004051.1|refseq:NP_001171803.1|refseq:NP_001171804.1|refseq:NP_001171805.1|refseq:NP_001186747.1|refseq:NP_612446.1|entrezgene/locuslink:114928(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16439984(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aUbvpCvGto1y4Rqnri7qaKaygQ89606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:WcECaDS6pZZZ8+Vb9HneFem3VFI	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96KN7-4	uniprotkb:P0C7X2	intact:EBI-11525164|ensembl:ENSP00000372391	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477339	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)|entrezgene/locuslink:57096(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16440378(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:R0V6KxExeohKy5kGOmnD7rgvHMo	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96KN7-4	uniprotkb:A0A0S2Z6P0	intact:EBI-11525164|ensembl:ENSP00000372391	intact:EBI-16429989	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477355	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)|entrezgene/locuslink:57096(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16440378(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:P+kfyheVI4t6gP5Z0sGMikFjAzM	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y5V3	uniprotkb:P0C7X2	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477371	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889|entrezgene/locuslink:9500(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16440614(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:i0IxYizsKcOrZmpc581iL27GK2c	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q9Y5V3	uniprotkb:A0A0S2Z6P0	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927	intact:EBI-16429989	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477387	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889|entrezgene/locuslink:9500(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16440614(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:xi6Kz7sJEQBF9vRcrmhn9aU4QHQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q12933	uniprotkb:P0C7X2	intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668	intact:EBI-4395732|uniprotkb:B3KV51|uniprotkb:O75701|uniprotkb:Q8IW91|uniprotkb:Q8WV14|uniprotkb:Q96MN0|uniprotkb:A8MV39|ensembl:ENSP00000223459	psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym)	psi-mi:zn688_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477403	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity)	refseq:NP_001019854.1|refseq:NP_660314.1|ensembl:ENSG00000229809(gene)|ensembl:ENST00000223459(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146542(identity)	intact:EBI-16440684(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606	rogid:ZP8beTaWW/kLZHt0j6Qu5d9Prsg9606	rigid:4QAt3KNBBXWuCCqRIrlbUHcsOCU	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)
uniprotkb:Q96D09	uniprotkb:A0A0S2Z6P0	intact:EBI-473189|ensembl:ENSP00000339057|ensembl:ENSP00000437394|ensembl:ENSP00000437872|ensembl:ENSP00000507692|ensembl:ENSP00000508139|uniprotkb:Q8NAB4|uniprotkb:D3DXA0	intact:EBI-16429989	psi-mi:gasp2_human(display_long)|uniprotkb:GPRASP2(gene name)|psi-mi:GPRASP2(display_short)	psi-mi:a0a0s2z6p0_human(display_long)|uniprotkb:ZNF688(gene name)|psi-mi:ZNF688(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2016)	pubmed:26871637|imex:IM-25013|doi:10.1016/j.cell.2016.01.029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16477307	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000158301(gene)|ensembl:ENST00000332262(transcript)|ensembl:ENST00000483720(transcript)|ensembl:ENST00000486814(transcript)|ensembl:ENST00000535209(transcript)|ensembl:ENST00000543253(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:NP_001004051.1|refseq:NP_001171803.1|refseq:NP_001171804.1|refseq:NP_001171805.1|refseq:NP_001186747.1|refseq:NP_612446.1|entrezgene/locuslink:114928(identity)	go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|entrezgene/locuslink:146542(identity)	intact:EBI-16439984(see-also)	-	-	caution:No direct evidence for expression of this isoform is given in the publication, but overall expression of the clones in the dataset has been tested in selected random clones in figures 2B and S2A-H, with 100% success ratio.|negative:The interaction does not occur under these experimental conditions.|figure legend:Supplementary table S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/02/15	2017/10/19	rogid:aUbvpCvGto1y4Rqnri7qaKaygQ89606	rogid:tJYK2TjSjpKqq8LuNRTxP0k/29s9606	rigid:my4AO1HKqtFHUmVaqCVNPLBoBIQ	true	-	-	-	-	psi-mi:"MI:1179"(partial nucleotide sequence identification)	psi-mi:"MI:1179"(partial nucleotide sequence identification)