#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q15078	uniprotkb:O89053	intact:EBI-746189|uniprotkb:Q5U0G3|uniprotkb:E1P664|ensembl:ENSP00000318486	intact:EBI-6665847|ensembl:ENSMUSP00000032949|ensembl:ENSMUSP00000101972|uniprotkb:Q7TMU0|uniprotkb:Q9R1Y8|uniprotkb:Q9R288	psi-mi:cd5r1_human(display_long)|uniprotkb:Cyclin-dependent kinase 5 regulatory subunit 1(gene name synonym)|uniprotkb:TPKII regulatory subunit(gene name synonym)|uniprotkb:CDK5R1(gene name)|psi-mi:CDK5R1(display_short)|uniprotkb:CDK5R(gene name synonym)|uniprotkb:NCK5A(gene name synonym)	psi-mi:cor1a_mouse(display_long)|uniprotkb:Coro1a(gene name)|psi-mi:Coro1a(display_short)|uniprotkb:Coro1(gene name synonym)|uniprotkb:Coronin-like protein A(gene name synonym)|uniprotkb:Coronin-like protein p57(gene name synonym)|uniprotkb:Tryptophan aspartate-containing coat protein(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Liu et al. (2016)	imex:IM-25026|pubmed:26823173	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-11600074|imex:IM-25026-1	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003876.1|refseq:XP_011523740.1|ensembl:ENSG00000176749(gene)|ensembl:ENST00000313401(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0002020"(protease binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016533"(protein kinase 5 complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021722"(superior olivary nucleus maturation)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042501"(serine phosphorylation of STAT protein)|go:"GO:0043005"(neuron projection)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0043292"(contractile fiber)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:2000273"(positive regulation of signaling receptor activity)|interpro:IPR004944(Cyclin-dependent kinase 5 activator)|interpro:IPR036915|rcsb pdb:1H4L|rcsb pdb:1UNG|rcsb pdb:1UNH|rcsb pdb:1UNL|rcsb pdb:3O0G|rcsb pdb:6LDP|rcsb pdb:7CNG|reactome:R-HSA-399956|reactome:R-HSA-6804756|reactome:R-HSA-8862803|reactome:R-HSA-9031628|reactome:R-HSA-9032845|refseq:XP_016880770.1|dip:DIP-24222N	refseq:NP_001288303.1|ensembl:ENSMUSG00000030707(gene)|ensembl:ENSMUST00000032949(transcript)|ensembl:ENSMUST00000106364(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031339"(negative regulation of vesicle fusion)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032796"(uropod organization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0061502"(early endosome to recycling endosome transport)|go:"GO:0005769"(early endosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015049(Region of unknown function DUF1900)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029508|interpro:IPR036322|mint:O89053|rcsb pdb:2AKF|rcsb pdb:2AQ5|rcsb pdb:2B4E|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_006507347.1|refseq:XP_006507348.1|refseq:NP_034028.1	-	-	-	figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/02/19	2016/02/19	rogid:v4E2UWg0EgZM8lUhSUpirwaIONw9606	rogid:vHdYGwxsKBH6rjydlvwYZ54AweQ10090	rigid:8Shl5d/RFMwruiq/oZzPNnwv70M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:O89053	uniprotkb:P63092	intact:EBI-6665847|ensembl:ENSMUSP00000032949|ensembl:ENSMUSP00000101972|uniprotkb:Q7TMU0|uniprotkb:Q9R1Y8|uniprotkb:Q9R288	intact:EBI-1047114|uniprotkb:P04895|uniprotkb:Q12927|uniprotkb:Q5JWD2|uniprotkb:Q5JWD4|uniprotkb:Q5JWD5|uniprotkb:Q6NR75|uniprotkb:Q6NXS0|uniprotkb:Q8TBC0|uniprotkb:Q96H70|uniprotkb:Q14433|uniprotkb:Q32P26|uniprotkb:E1P5G5|ensembl:ENSP00000360126|uniprotkb:A6NI00|intact:EBI-10977858	psi-mi:cor1a_mouse(display_long)|uniprotkb:Coro1a(gene name)|psi-mi:Coro1a(display_short)|uniprotkb:Coro1(gene name synonym)|uniprotkb:Coronin-like protein A(gene name synonym)|uniprotkb:Coronin-like protein p57(gene name synonym)|uniprotkb:Tryptophan aspartate-containing coat protein(gene name synonym)	psi-mi:gnas2_human(display_long)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:GNAS1(gene name synonym)|uniprotkb:GSP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2016)	imex:IM-25026|pubmed:26823173	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11600181|imex:IM-25026-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001288303.1|ensembl:ENSMUSG00000030707(gene)|ensembl:ENSMUST00000032949(transcript)|ensembl:ENSMUST00000106364(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031339"(negative regulation of vesicle fusion)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032796"(uropod organization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0061502"(early endosome to recycling endosome transport)|go:"GO:0005769"(early endosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015049(Region of unknown function DUF1900)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029508|interpro:IPR036322|mint:O89053|rcsb pdb:2AKF|rcsb pdb:2AQ5|rcsb pdb:2B4E|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_006507347.1|refseq:XP_006507348.1|refseq:NP_034028.1	refseq:NP_001070958.1|refseq:NP_001296769.1|refseq:NP_536350.2|refseq:NP_000507.1|refseq:NP_001070956.1|refseq:NP_001070957.1|ensembl:ENSG00000087460(gene)|ensembl:ENST00000371085(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0048589"(developmental growth)|go:"GO:0050890"(cognition)|go:"GO:0060348"(bone development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63092|rcsb pdb:5G53|rcsb pdb:5UZ7|rcsb pdb:5VAI|rcsb pdb:6AU6|rcsb pdb:6B3J|rcsb pdb:6E3Y|rcsb pdb:6E67|rcsb pdb:6EG8|rcsb pdb:6GDG|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LPB|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6ORV|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VN7|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XOX|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7BPH|rcsb pdb:7BW0|rcsb pdb:7BZ2|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX3|rcsb pdb:7CX4|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7D7M|rcsb pdb:7DHI|rcsb pdb:7DHR|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7KH0|rcsb pdb:7LCI|rcsb pdb:7LJC|rcsb pdb:7LJD|rcsb pdb:7MBX|reactome:R-HSA-163359|reactome:R-HSA-164378|reactome:R-HSA-381676|reactome:R-HSA-392851|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-432040|reactome:R-HSA-5610787|reactome:R-HSA-9660821|refseq:NP_536351.1	-	-	-	figure legend:f2c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mel_juso)|taxid:9606(Homo sapiens)	-	2016/02/19	2016/02/19	rogid:vHdYGwxsKBH6rjydlvwYZ54AweQ10090	rogid:fUnrdxwx4bBAqE3iO2cCB3UInyg9606	rigid:rNR6bOaZk5n1x/BF/NHJzto3qQE	false	mutation decreasing interaction:418-418|mutation decreasing interaction:424-424|mutation disrupting interaction:418-418,424-424	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O89053	uniprotkb:P63092	intact:EBI-6665847|ensembl:ENSMUSP00000032949|ensembl:ENSMUSP00000101972|uniprotkb:Q7TMU0|uniprotkb:Q9R1Y8|uniprotkb:Q9R288	intact:EBI-1047114|uniprotkb:P04895|uniprotkb:Q12927|uniprotkb:Q5JWD2|uniprotkb:Q5JWD4|uniprotkb:Q5JWD5|uniprotkb:Q6NR75|uniprotkb:Q6NXS0|uniprotkb:Q8TBC0|uniprotkb:Q96H70|uniprotkb:Q14433|uniprotkb:Q32P26|uniprotkb:E1P5G5|ensembl:ENSP00000360126|uniprotkb:A6NI00|intact:EBI-10977858	psi-mi:cor1a_mouse(display_long)|uniprotkb:Coro1a(gene name)|psi-mi:Coro1a(display_short)|uniprotkb:Coro1(gene name synonym)|uniprotkb:Coronin-like protein A(gene name synonym)|uniprotkb:Coronin-like protein p57(gene name synonym)|uniprotkb:Tryptophan aspartate-containing coat protein(gene name synonym)	psi-mi:gnas2_human(display_long)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:GNAS1(gene name synonym)|uniprotkb:GSP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2016)	imex:IM-25026|pubmed:26823173	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11600249|imex:IM-25026-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001288303.1|ensembl:ENSMUSG00000030707(gene)|ensembl:ENSMUST00000032949(transcript)|ensembl:ENSMUST00000106364(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031339"(negative regulation of vesicle fusion)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032796"(uropod organization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0061502"(early endosome to recycling endosome transport)|go:"GO:0005769"(early endosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015049(Region of unknown function DUF1900)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029508|interpro:IPR036322|mint:O89053|rcsb pdb:2AKF|rcsb pdb:2AQ5|rcsb pdb:2B4E|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_006507347.1|refseq:XP_006507348.1|refseq:NP_034028.1	refseq:NP_001070958.1|refseq:NP_001296769.1|refseq:NP_536350.2|refseq:NP_000507.1|refseq:NP_001070956.1|refseq:NP_001070957.1|ensembl:ENSG00000087460(gene)|ensembl:ENST00000371085(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0048589"(developmental growth)|go:"GO:0050890"(cognition)|go:"GO:0060348"(bone development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63092|rcsb pdb:5G53|rcsb pdb:5UZ7|rcsb pdb:5VAI|rcsb pdb:6AU6|rcsb pdb:6B3J|rcsb pdb:6E3Y|rcsb pdb:6E67|rcsb pdb:6EG8|rcsb pdb:6GDG|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LPB|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6ORV|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VN7|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XOX|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7BPH|rcsb pdb:7BW0|rcsb pdb:7BZ2|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX3|rcsb pdb:7CX4|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7D7M|rcsb pdb:7DHI|rcsb pdb:7DHR|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7KH0|rcsb pdb:7LCI|rcsb pdb:7LJC|rcsb pdb:7LJD|rcsb pdb:7MBX|reactome:R-HSA-163359|reactome:R-HSA-164378|reactome:R-HSA-381676|reactome:R-HSA-392851|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-432040|reactome:R-HSA-5610787|reactome:R-HSA-9660821|refseq:NP_536351.1	-	-	-	figure legend:f3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mel_juso)|taxid:9606(Homo sapiens)	-	2016/02/19	2016/02/19	rogid:vHdYGwxsKBH6rjydlvwYZ54AweQ10090	rogid:fUnrdxwx4bBAqE3iO2cCB3UInyg9606	rigid:rNR6bOaZk5n1x/BF/NHJzto3qQE	false	mutation decreasing interaction:418-418|mutation decreasing interaction:424-424|mutation disrupting interaction:418-418,424-424	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)