#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P26570	uniprotkb:P36024	intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8	intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C	psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name)	psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683439|imex:IM-25082-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N	refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024	-	crc64:8B7F009521F72C15	-	figure legend:Fig 2A|comment:The E. coli DnaK chaperone copurifies with the PPZ1 bait as a contaminant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/04/04	2016/04/04	rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292	rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292	rigid:u4cf20lMa8VKz3P+Y3/CNTQFeoo	false	sufficient binding region:345-692|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P26570	uniprotkb:P36024	intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8	intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C	psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name)	psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683456|imex:IM-25082-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N	refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024	-	crc64:8B7F009521F72C15	-	figure legend:Fig 2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2016/04/04	2016/04/08	rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292	rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292	rigid:u4cf20lMa8VKz3P+Y3/CNTQFeoo	false	sufficient binding region:345-692|his tag:n-n	-	1	1	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q08438	uniprotkb:P36076	intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C	intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W	psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name)	psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short)	psi-mi:"MI:0096"(pull down)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683489|imex:IM-25082-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551	refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783	-	crc64:A97623473CB6F605	-	figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2016/04/04	2016/04/04	rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292	rogid:Li7vZOassm4PC5fW111/j5ivgEc559292	rigid:qp11f8iSzWs2ko+M67OFV8ETXt8	false	sufficient binding region:288-577(IPR003382)|his tag:n-n	sufficient binding region:305-508(IPR003382)	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q08438	uniprotkb:P36024	intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C	intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C	psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name)	psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683489|imex:IM-25082-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551	refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024	-	crc64:A97623473CB6F605	-	figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2016/04/04	2016/04/04	rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292	rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292	rigid:qp11f8iSzWs2ko+M67OFV8ETXt8	false	sufficient binding region:288-577(IPR003382)|his tag:n-n	sufficient binding region:256-480(IPR003382)|his tag:n-n	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P36076	uniprotkb:P36024	intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W	intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C	psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short)	psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683507|imex:IM-25082-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783	refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024	-	-	-	figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2016/04/04	2016/04/04	rogid:Li7vZOassm4PC5fW111/j5ivgEc559292	rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292	rigid:w+Dyw0kudYkd6B6rHxz3iztH/AA	false	sufficient binding region:305-508(IPR003382)	sufficient binding region:256-480(IPR003382)|his tag:n-n	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P36076	uniprotkb:Q08438	intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W	intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C	psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short)	psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name)	psi-mi:"MI:0096"(pull down)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683519|imex:IM-25082-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783	refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551	-	-	crc64:A97623473CB6F605	figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2016/04/04	2016/04/04	rogid:Li7vZOassm4PC5fW111/j5ivgEc559292	rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292	rigid:g8JD/Rsz9EvbVR6Upimp3T8UhJQ	false	sufficient binding region:305-508(IPR003382)	sufficient binding region:288-577(IPR003382)|his tag:n-n	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
chebi:"CHEBI:15769"	uniprotkb:P36076	intact:EBI-11707792|chebi:"CHEBI:10987"|chebi:"CHEBI:12438"|chebi:"CHEBI:328"|chebi:"CHEBI:21461"	intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W	psi-mi:"n-[(r)-4-phosphopantothenoyl]-l-cysteine"(display_short)|psi-mi:"CHEBI:15769"(display_long)|intact:"(R)-4'-Phosphopantothenoyl-L-cysteine"(synonym)|intact:"N-((R)-4'-phosphopantothenoyl)-L-cysteine"(synonym)|intact:"N-[(R)-4'-Phosphopantothenoyl]-L-cysteine"(synonym)|intact:"N-{N-[(2R)-2-hydroxy-3,3-dimethyl-4-phosphonooxybutanoyl]-beta-alanyl}-L-cysteine"(iupac name)	psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short)	psi-mi:"MI:1138"(decarboxylation assay)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:1140"(decarboxylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683582|imex:IM-25082-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783	go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/04/04	2016/05/26	-	rogid:Li7vZOassm4PC5fW111/j5ivgEc559292	-	false	-	sufficient binding region:305-508(IPR003382)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36076	uniprotkb:Q08438	intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W	intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C	psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short)	psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name)	psi-mi:"MI:1138"(decarboxylation assay)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:1140"(decarboxylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683582|imex:IM-25082-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783	refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551	go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)	-	crc64:A97623473CB6F605	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/04/04	2016/05/26	rogid:Li7vZOassm4PC5fW111/j5ivgEc559292	rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292	-	false	sufficient binding region:305-508(IPR003382)	sufficient binding region:288-577(IPR003382)|his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15769"	uniprotkb:P36076	intact:EBI-11707792|chebi:"CHEBI:10987"|chebi:"CHEBI:12438"|chebi:"CHEBI:328"|chebi:"CHEBI:21461"	intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W	psi-mi:"n-[(r)-4-phosphopantothenoyl]-l-cysteine"(display_short)|psi-mi:"CHEBI:15769"(display_long)|intact:"(R)-4'-Phosphopantothenoyl-L-cysteine"(synonym)|intact:"N-((R)-4'-phosphopantothenoyl)-L-cysteine"(synonym)|intact:"N-[(R)-4'-Phosphopantothenoyl]-L-cysteine"(synonym)|intact:"N-{N-[(2R)-2-hydroxy-3,3-dimethyl-4-phosphonooxybutanoyl]-beta-alanyl}-L-cysteine"(iupac name)	psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short)	psi-mi:"MI:1138"(decarboxylation assay)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:1140"(decarboxylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683570|imex:IM-25082-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783	go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/04/04	2016/05/26	-	rogid:Li7vZOassm4PC5fW111/j5ivgEc559292	-	false	-	sufficient binding region:305-508(IPR003382)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36076	uniprotkb:P36024	intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W	intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C	psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short)	psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym)	psi-mi:"MI:1138"(decarboxylation assay)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:1140"(decarboxylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683570|imex:IM-25082-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783	refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024	go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/04/04	2016/05/26	rogid:Li7vZOassm4PC5fW111/j5ivgEc559292	rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292	-	false	sufficient binding region:305-508(IPR003382)	sufficient binding region:256-480(IPR003382)|his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15769"	intenz:4.1.1.36	intact:EBI-11707792|chebi:"CHEBI:10987"|chebi:"CHEBI:12438"|chebi:"CHEBI:328"|chebi:"CHEBI:21461"	intact:EBI-11683595	psi-mi:"n-[(r)-4-phosphopantothenoyl]-l-cysteine"(display_short)|psi-mi:"CHEBI:15769"(display_long)|intact:"(R)-4'-Phosphopantothenoyl-L-cysteine"(synonym)|intact:"N-((R)-4'-phosphopantothenoyl)-L-cysteine"(synonym)|intact:"N-[(R)-4'-Phosphopantothenoyl]-L-cysteine"(synonym)|intact:"N-{N-[(2R)-2-hydroxy-3,3-dimethyl-4-phosphonooxybutanoyl]-beta-alanyl}-L-cysteine"(iupac name)	psi-mi:ppcdc_yeast(display_short)|psi-mi:4.1.1.36(display_long)|intact:Phosphopantothenoylcysteine decarboxylase complex(complex recommended name)|intact:PPCDC complex(complex synonym)|intact:"CAB3:SIS2:VHS3"(complex systematic name)|intact:PPC-DC complex(complex synonym)|intact:CoaC complex(complex synonym)|intact:CoA caroxylase complex(complex synonym)|intact:Hal3-Vhs3-Cab3 complex(complex synonym)	psi-mi:"MI:1138"(decarboxylation assay)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:1140"(decarboxylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683552|imex:IM-25082-18	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:1302"(stable complex)	-	go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|evidence ontology:"ECO:0000353"|go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)|go:"GO:0015937"(coenzyme A biosynthetic process)|intact:EBI-11683921(exp-evidence)|pubmed:26514574(see-also)|complex portal:CPX-393(complex-primary)	go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)	-	curated-complex:"Catalyses the third step of the coenzyme A (CoA) biosynthetic pathway, namely the decarboxylation of 4'-phosphopantothenoylcysteine to form 4′-phosphopantetheine. May potentially be part of a larger Coenzyme A-synthesizing protein complex (CPX-396) but this is not yet clear.    The synthesis of CoA involves the phosphorylation of pantothenate (vitamin B5) to 4'-phosphopantothenate, to which a cysteine is then added to form   4'-phospho-N-pantothenoylcysteine (PCC). PPC is decarboxylated to 4'-phosphopantetheine by phosphopantothenoylcysteine decarboxylase (this complex). 4'-phosphopantetheine is adenylylated to form dephospho-CoA which is then phosphorylated to form coenzyme A."|complex-properties:"Two catalytically essential residues are required - His that is required for the first step of the enzyme’s two-step mechanism (an oxidative decarboxylation), and a Cys that is necessary for the second step (the reduction of the reaction intermediate). These are found on opposite sides of the active site, with VHS3 contributing the His residue whilst CAB3 contributes the Cys residue to give a complex with a single functional active site."|complex-assembly:Heterotrimer	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/04/04	2016/05/26	-	-	-	false	-	sufficient binding region:305-508|sufficient binding region:256-480|sufficient binding region:288-577|his tag:n-n|his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15769"	uniprotkb:Q96CD2	intact:EBI-11707792|chebi:"CHEBI:10987"|chebi:"CHEBI:12438"|chebi:"CHEBI:328"|chebi:"CHEBI:21461"	intact:EBI-724333|uniprotkb:Q96SX0|ensembl:ENSP00000343190|uniprotkb:Q9HC17	psi-mi:"n-[(r)-4-phosphopantothenoyl]-l-cysteine"(display_short)|psi-mi:"CHEBI:15769"(display_long)|intact:"(R)-4'-Phosphopantothenoyl-L-cysteine"(synonym)|intact:"N-((R)-4'-phosphopantothenoyl)-L-cysteine"(synonym)|intact:"N-[(R)-4'-Phosphopantothenoyl]-L-cysteine"(synonym)|intact:"N-{N-[(2R)-2-hydroxy-3,3-dimethyl-4-phosphonooxybutanoyl]-beta-alanyl}-L-cysteine"(iupac name)	psi-mi:coac_human(display_long)|uniprotkb:CoaC(gene name synonym)|uniprotkb:PPCDC(gene name)|psi-mi:PPCDC(display_short)|uniprotkb:COAC(gene name synonym)|uniprotkb:MDS018(orf name)|uniprotkb:UNQ9365/PRO34154(orf name)	psi-mi:"MI:1138"(decarboxylation assay)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:1140"(decarboxylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683668|imex:IM-25082-8	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_068595.3|rcsb pdb:1QZU|reactome:R-HSA-196783|mint:Q96CD2|ensembl:ENSG00000138621(gene)|ensembl:ENST00000342932(transcript)|go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|refseq:NP_001288030.1|refseq:NP_001288031.1|refseq:NP_001288032.1|refseq:NP_001288033.1|refseq:NP_001288034.1	go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/04/04	2016/05/26	-	rogid:2d686R1m4jA5uWpf/8O6rI6/Olo9606	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36024	uniprotkb:P36024	intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C	intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C	psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym)	psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683697|imex:IM-25082-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024	refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024	-	-	-	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/04/04	2016/04/04	rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292	rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292	rigid:M9aWLbS9+G+XDSvaqUqEX6Lmy6Y	false	sufficient binding region:256-480(IPR003382)|his tag:n-n	sufficient binding region:256-480(IPR003382)|his tag:n-n	3	0	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P36024	uniprotkb:P36024	intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C	intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C	psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym)	psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683709|imex:IM-25082-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024	refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024	-	-	-	figure legend:Fig. 4A|comment:The presence of dimers is assumed to be due to incomplete crosslinking.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/04/04	2016/04/04	rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292	rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292	rigid:M9aWLbS9+G+XDSvaqUqEX6Lmy6Y	false	sufficient binding region:256-480(IPR003382)|his tag:n-n	sufficient binding region:256-480(IPR003382)|his tag:n-n	2	0	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q08438	uniprotkb:Q08438	intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C	intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C	psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name)	psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name)	psi-mi:"MI:0030"(cross-linking study)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683721|imex:IM-25082-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551	refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551	-	crc64:A97623473CB6F605	crc64:A97623473CB6F605	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/04/04	2016/04/04	rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292	rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292	rigid:tdN5FWSwwl/hXmG5+BiZ73qCKjI	false	sufficient binding region:288-577(IPR003382)|his tag:n-n	sufficient binding region:288-577(IPR003382)|his tag:n-n	3	0	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q08438	uniprotkb:Q08438	intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C	intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C	psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name)	psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name)	psi-mi:"MI:0030"(cross-linking study)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683740|imex:IM-25082-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551	refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551	-	crc64:A97623473CB6F605	crc64:A97623473CB6F605	figure legend:Fig. 4A|comment:The presence of dimers is assumed to be due to incomplete crosslinking.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/04/04	2016/04/04	rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292	rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292	rigid:tdN5FWSwwl/hXmG5+BiZ73qCKjI	false	sufficient binding region:288-577(IPR003382)|his tag:n-n	sufficient binding region:288-577(IPR003382)|his tag:n-n	2	0	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q96CD2	uniprotkb:Q96CD2	intact:EBI-724333|uniprotkb:Q96SX0|ensembl:ENSP00000343190|uniprotkb:Q9HC17	intact:EBI-724333|uniprotkb:Q96SX0|ensembl:ENSP00000343190|uniprotkb:Q9HC17	psi-mi:coac_human(display_long)|uniprotkb:CoaC(gene name synonym)|uniprotkb:PPCDC(gene name)|psi-mi:PPCDC(display_short)|uniprotkb:COAC(gene name synonym)|uniprotkb:MDS018(orf name)|uniprotkb:UNQ9365/PRO34154(orf name)	psi-mi:coac_human(display_long)|uniprotkb:CoaC(gene name synonym)|uniprotkb:PPCDC(gene name)|psi-mi:PPCDC(display_short)|uniprotkb:COAC(gene name synonym)|uniprotkb:MDS018(orf name)|uniprotkb:UNQ9365/PRO34154(orf name)	psi-mi:"MI:0071"(molecular sieving)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683768|imex:IM-25082-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068595.3|rcsb pdb:1QZU|reactome:R-HSA-196783|mint:Q96CD2|ensembl:ENSG00000138621(gene)|ensembl:ENST00000342932(transcript)|go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|refseq:NP_001288030.1|refseq:NP_001288031.1|refseq:NP_001288032.1|refseq:NP_001288033.1|refseq:NP_001288034.1	refseq:NP_068595.3|rcsb pdb:1QZU|reactome:R-HSA-196783|mint:Q96CD2|ensembl:ENSG00000138621(gene)|ensembl:ENST00000342932(transcript)|go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|refseq:NP_001288030.1|refseq:NP_001288031.1|refseq:NP_001288032.1|refseq:NP_001288033.1|refseq:NP_001288034.1	-	-	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2016/04/04	2016/04/04	rogid:2d686R1m4jA5uWpf/8O6rI6/Olo9606	rogid:2d686R1m4jA5uWpf/8O6rI6/Olo9606	rigid:VayK/IjDSqQv/WRgInHe3Ls5iyo	false	-	-	3	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36024	uniprotkb:P36024	intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C	intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C	psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym)	psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683847|imex:IM-25082-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024	refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024	-	-	-	figure legend:Fig. 4C|comment:Additional higher molecular weight oligomers appear to form.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2016/04/04	2016/04/04	rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292	rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292	rigid:M9aWLbS9+G+XDSvaqUqEX6Lmy6Y	false	sufficient binding region:256-480(IPR003382)	sufficient binding region:256-480(IPR003382)	3	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08438	uniprotkb:Q08438	intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C	intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C	psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name)	psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name)	psi-mi:"MI:0071"(molecular sieving)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683855|imex:IM-25082-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551	refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551	-	crc64:A97623473CB6F605	crc64:A97623473CB6F605	figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2016/04/04	2016/04/04	rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292	rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292	rigid:tdN5FWSwwl/hXmG5+BiZ73qCKjI	false	sufficient binding region:288-577(IPR003382)	sufficient binding region:288-577(IPR003382)	3	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36076	uniprotkb:P36024	intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W	intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C	psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short)	psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683909|imex:IM-25082-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783	refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024	-	-	-	figure legend:Fig. 4E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2016/04/04	2016/04/04	rogid:Li7vZOassm4PC5fW111/j5ivgEc559292	rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292	rigid:w+Dyw0kudYkd6B6rHxz3iztH/AA	false	sufficient binding region:305-508(IPR003382)	sufficient binding region:256-480(IPR003382)	3	3	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36076	uniprotkb:P36024	intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W	intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C	psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short)	psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683921|imex:IM-25082-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783	refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024	-	-	-	figure legend:Fig. 4F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2016/04/04	2016/04/04	rogid:Li7vZOassm4PC5fW111/j5ivgEc559292	rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292	rigid:qp11f8iSzWs2ko+M67OFV8ETXt8	false	sufficient binding region:305-508(IPR003382)	sufficient binding region:256-480(IPR003382)	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36076	uniprotkb:Q08438	intact:EBI-26778|uniprotkb:D6VXK0|ensemblfungi:YKL088W	intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C	psi-mi:cab3_yeast(display_long)|uniprotkb:YKL088W(locus name)|uniprotkb:CAB3(gene name)|psi-mi:CAB3(display_short)	psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name)	psi-mi:"MI:0071"(molecular sieving)	Abrie et al. (2014)	pubmed:26514574|imex:IM-25082	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11683921|imex:IM-25082-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012835.1|sgd:S000001571|mint:P36076|dip:DIP-4475N|ensemblfungi:YKL088W(gene)|ensemblfungi:YKL088W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|reactome:R-SCE-196783	refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551	-	-	crc64:A97623473CB6F605	figure legend:Fig. 4F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2016/04/04	2016/04/04	rogid:Li7vZOassm4PC5fW111/j5ivgEc559292	rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292	rigid:qp11f8iSzWs2ko+M67OFV8ETXt8	false	sufficient binding region:305-508(IPR003382)	sufficient binding region:288-577(IPR003382)	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)