#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12464 uniprotkb:P38768 intact:EBI-31814|uniprotkb:D6W3D5|ensemblfungi:YPL235W intact:EBI-24499|uniprotkb:D3DKY1|ensemblfungi:YHR034C psi-mi:ruvb2_yeast(display_long)|uniprotkb:TIP49-homology protein 2(gene name synonym)|uniprotkb:TIP49b homolog(gene name synonym)|uniprotkb:RVB2(gene name)|psi-mi:RVB2(display_short)|uniprotkb:TIH2(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:YPL235W(locus name)|uniprotkb:P1060(orf name) psi-mi:pih1_yeast(display_long)|uniprotkb:PIH1(gene name)|psi-mi:PIH1(display_short)|uniprotkb:NOP17(gene name synonym)|uniprotkb:Nucleolar protein 17(gene name synonym)|uniprotkb:YHR034C(locus name) psi-mi:"MI:0018"(two hybrid) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11660661|imex:IM-25111-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015089.1|sgd:S000006156|dip:DIP-5207N|mint:Q12464|ensemblfungi:YPL235W(gene)|ensemblfungi:YPL235W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0070209"(ASTRA complex)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|rcsb pdb:5OUN|rcsb pdb:6GEJ|rcsb pdb:6GEN refseq:NP_011899.1|sgd:S000001076|dip:DIP-807N|mint:P38768|ensemblfungi:YHR034C(gene)|ensemblfungi:YHR034C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008380"(RNA splicing)|go:"GO:0097255"(R2TP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012981(Nop17p)|interpro:IPR041441|rcsb pdb:2MNJ|rcsb pdb:4CGU|rcsb pdb:4CHH - crc64:0D8EFBA7EC711AB8 crc64:02C06D0A113B1B3B figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/03/18 2016/03/21 rogid:+msMK6AgZ+aJt0cpuIV7g6JtWr4559292 rogid:5z/tmH0iorWwa2yX80ZUuQAZEQw559292 rigid:cIvs5NMek0tMcrT3DgLr0l72dz8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25359 uniprotkb:Q08962 intact:EBI-1773|uniprotkb:Q8NKJ5|ensemblfungi:YCR035C|uniprotkb:D6VR45 intact:EBI-12067|uniprotkb:D6W3F9|ensemblfungi:YPL211W psi-mi:rrp43_yeast(display_long)|uniprotkb:RRP43(gene name)|psi-mi:RRP43(display_short)|uniprotkb:YCR035C(locus name)|uniprotkb:YCR35C(orf name)|uniprotkb:YCR522(orf name)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym) psi-mi:nip7_yeast(display_long)|uniprotkb:YPL211W(locus name)|uniprotkb:NIP7(gene name)|psi-mi:NIP7(display_short)|uniprotkb:Nuclear import protein 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11660696|imex:IM-25111-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR035C(gene)|ensemblfungi:YCR035C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016072"(rRNA metabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|refseq:NP_009964.2|sgd:S000000631|dip:DIP-5485N|mint:P25359|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 ensemblfungi:YPL211W(gene)|ensemblfungi:YPL211W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR002478(PUA)|interpro:IPR005155(Ribosome biogenesis factor NIP7-like)|interpro:IPR015947(PUA-like)|interpro:IPR016686(Ribosome biogenesis factor, NIP7)|interpro:IPR036974|interpro:IPR040598|rcsb pdb:6ELZ|go:"GO:0003723"(RNA binding)|rcsb pdb:6EM5|refseq:NP_015113.1|sgd:S000006132|mint:Q08962|dip:DIP-1456N - crc64:8801837B8184134D crc64:82EAE8E4B2FCC31A figure legend:Fig 1A, C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/03/18 2016/03/21 rogid:htGDTlKKMq7OdwcfGUKgfWCjJ1k559292 rogid:VVPB1u3oRbh7O35Bzm6G7yHRLsE559292 rigid:KSfikmexYcOhaBRXq8Z/SHPhdmc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03940 uniprotkb:P38768 intact:EBI-30712|uniprotkb:D6VSH3|ensemblfungi:YDR190C intact:EBI-24499|uniprotkb:D3DKY1|ensemblfungi:YHR034C psi-mi:ruvb1_yeast(display_long)|uniprotkb:RVB1(gene name)|psi-mi:RVB1(display_short)|uniprotkb:TIP49-homology protein 1(gene name synonym)|uniprotkb:TIP49a homolog(gene name synonym)|uniprotkb:TIH1(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:YDR190C(locus name) psi-mi:pih1_yeast(display_long)|uniprotkb:PIH1(gene name)|psi-mi:PIH1(display_short)|uniprotkb:NOP17(gene name synonym)|uniprotkb:Nucleolar protein 17(gene name synonym)|uniprotkb:YHR034C(locus name) psi-mi:"MI:0018"(two hybrid) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11660876|imex:IM-25111-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010476.1|sgd:S000002598|dip:DIP-4896N|mint:Q03940|ensemblfungi:YDR190C(gene)|ensemblfungi:YDR190C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0070209"(ASTRA complex)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|rcsb pdb:6GEJ|rcsb pdb:6GEN|reactome:R-SCE-5689880 refseq:NP_011899.1|sgd:S000001076|dip:DIP-807N|mint:P38768|ensemblfungi:YHR034C(gene)|ensemblfungi:YHR034C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008380"(RNA splicing)|go:"GO:0097255"(R2TP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012981(Nop17p)|interpro:IPR041441|rcsb pdb:2MNJ|rcsb pdb:4CGU|rcsb pdb:4CHH - crc64:93D6ECB7006AF0F2 crc64:02C06D0A113B1B3B figure legend:Fig 1 A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/03/18 2016/03/21 rogid:tVQiqr2rPrfXb1Wb/2XUOTBBXIQ559292 rogid:5z/tmH0iorWwa2yX80ZUuQAZEQw559292 rigid:lwmdz7iQ5sC6UDYFSHwRaLTd98A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08287 uniprotkb:Q08962 intact:EBI-12135|uniprotkb:D6W1S5|ensemblfungi:YOL144W intact:EBI-12067|uniprotkb:D6W3F9|ensemblfungi:YPL211W psi-mi:nop8_yeast(display_long)|uniprotkb:YOL144W(locus name)|uniprotkb:Nucleolar protein 8(gene name synonym)|uniprotkb:NOP8(gene name)|psi-mi:NOP8(display_short) psi-mi:nip7_yeast(display_long)|uniprotkb:YPL211W(locus name)|uniprotkb:NIP7(gene name)|psi-mi:NIP7(display_short)|uniprotkb:Nuclear import protein 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11660881|imex:IM-25111-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034138|interpro:IPR035979|ensemblfungi:YOL144W(gene)|ensemblfungi:YOL144W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|refseq:NP_014497.1|sgd:S000005504|dip:DIP-4206N|mint:Q08287 ensemblfungi:YPL211W(gene)|ensemblfungi:YPL211W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR002478(PUA)|interpro:IPR005155(Ribosome biogenesis factor NIP7-like)|interpro:IPR015947(PUA-like)|interpro:IPR016686(Ribosome biogenesis factor, NIP7)|interpro:IPR036974|interpro:IPR040598|rcsb pdb:6ELZ|go:"GO:0003723"(RNA binding)|rcsb pdb:6EM5|refseq:NP_015113.1|sgd:S000006132|mint:Q08962|dip:DIP-1456N - - crc64:82EAE8E4B2FCC31A figure legend:Fig 1A, C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/03/18 2016/03/21 rogid:PR7N6gE4Il6ofUCopWK8ztDDVFo559292 rogid:VVPB1u3oRbh7O35Bzm6G7yHRLsE559292 rigid:Yr/ZabWZkR6r/K6AfrlPlas+1eM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03940 uniprotkb:P38768 intact:EBI-30712|uniprotkb:D6VSH3|ensemblfungi:YDR190C intact:EBI-24499|uniprotkb:D3DKY1|ensemblfungi:YHR034C psi-mi:ruvb1_yeast(display_long)|uniprotkb:RVB1(gene name)|psi-mi:RVB1(display_short)|uniprotkb:TIP49-homology protein 1(gene name synonym)|uniprotkb:TIP49a homolog(gene name synonym)|uniprotkb:TIH1(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:YDR190C(locus name) psi-mi:pih1_yeast(display_long)|uniprotkb:PIH1(gene name)|psi-mi:PIH1(display_short)|uniprotkb:NOP17(gene name synonym)|uniprotkb:Nucleolar protein 17(gene name synonym)|uniprotkb:YHR034C(locus name) psi-mi:"MI:0018"(two hybrid) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11660941|imex:IM-25111-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010476.1|sgd:S000002598|dip:DIP-4896N|mint:Q03940|ensemblfungi:YDR190C(gene)|ensemblfungi:YDR190C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0070209"(ASTRA complex)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|rcsb pdb:6GEJ|rcsb pdb:6GEN|reactome:R-SCE-5689880 refseq:NP_011899.1|sgd:S000001076|dip:DIP-807N|mint:P38768|ensemblfungi:YHR034C(gene)|ensemblfungi:YHR034C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008380"(RNA splicing)|go:"GO:0097255"(R2TP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012981(Nop17p)|interpro:IPR041441|rcsb pdb:2MNJ|rcsb pdb:4CGU|rcsb pdb:4CHH - crc64:93D6ECB7006AF0F2 crc64:02C06D0A113B1B3B figure legend:Fig 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/03/18 2016/03/21 rogid:tVQiqr2rPrfXb1Wb/2XUOTBBXIQ559292 rogid:5z/tmH0iorWwa2yX80ZUuQAZEQw559292 rigid:lwmdz7iQ5sC6UDYFSHwRaLTd98A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12464 uniprotkb:Q03940 intact:EBI-31814|uniprotkb:D6W3D5|ensemblfungi:YPL235W intact:EBI-30712|uniprotkb:D6VSH3|ensemblfungi:YDR190C psi-mi:ruvb2_yeast(display_long)|uniprotkb:TIP49-homology protein 2(gene name synonym)|uniprotkb:TIP49b homolog(gene name synonym)|uniprotkb:RVB2(gene name)|psi-mi:RVB2(display_short)|uniprotkb:TIH2(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:YPL235W(locus name)|uniprotkb:P1060(orf name) psi-mi:ruvb1_yeast(display_long)|uniprotkb:RVB1(gene name)|psi-mi:RVB1(display_short)|uniprotkb:TIP49-homology protein 1(gene name synonym)|uniprotkb:TIP49a homolog(gene name synonym)|uniprotkb:TIH1(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:YDR190C(locus name) psi-mi:"MI:0018"(two hybrid) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11660945|imex:IM-25111-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015089.1|sgd:S000006156|dip:DIP-5207N|mint:Q12464|ensemblfungi:YPL235W(gene)|ensemblfungi:YPL235W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0070209"(ASTRA complex)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|rcsb pdb:5OUN|rcsb pdb:6GEJ|rcsb pdb:6GEN refseq:NP_010476.1|sgd:S000002598|dip:DIP-4896N|mint:Q03940|ensemblfungi:YDR190C(gene)|ensemblfungi:YDR190C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0070209"(ASTRA complex)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|rcsb pdb:6GEJ|rcsb pdb:6GEN|reactome:R-SCE-5689880 - crc64:0D8EFBA7EC711AB8 crc64:93D6ECB7006AF0F2 figure legend:Fig 1 A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/03/18 2016/03/21 rogid:+msMK6AgZ+aJt0cpuIV7g6JtWr4559292 rogid:tVQiqr2rPrfXb1Wb/2XUOTBBXIQ559292 rigid:aiD+5PyCVug+doNtNHVVgpUQKio false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12464 uniprotkb:Q03940 intact:EBI-31814|uniprotkb:D6W3D5|ensemblfungi:YPL235W intact:EBI-30712|uniprotkb:D6VSH3|ensemblfungi:YDR190C psi-mi:ruvb2_yeast(display_long)|uniprotkb:TIP49-homology protein 2(gene name synonym)|uniprotkb:TIP49b homolog(gene name synonym)|uniprotkb:RVB2(gene name)|psi-mi:RVB2(display_short)|uniprotkb:TIH2(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:YPL235W(locus name)|uniprotkb:P1060(orf name) psi-mi:ruvb1_yeast(display_long)|uniprotkb:RVB1(gene name)|psi-mi:RVB1(display_short)|uniprotkb:TIP49-homology protein 1(gene name synonym)|uniprotkb:TIP49a homolog(gene name synonym)|uniprotkb:TIH1(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:YDR190C(locus name) psi-mi:"MI:0018"(two hybrid) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11660956|imex:IM-25111-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015089.1|sgd:S000006156|dip:DIP-5207N|mint:Q12464|ensemblfungi:YPL235W(gene)|ensemblfungi:YPL235W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0070209"(ASTRA complex)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|rcsb pdb:5OUN|rcsb pdb:6GEJ|rcsb pdb:6GEN refseq:NP_010476.1|sgd:S000002598|dip:DIP-4896N|mint:Q03940|ensemblfungi:YDR190C(gene)|ensemblfungi:YDR190C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0070209"(ASTRA complex)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|rcsb pdb:6GEJ|rcsb pdb:6GEN|reactome:R-SCE-5689880 - crc64:0D8EFBA7EC711AB8 crc64:93D6ECB7006AF0F2 figure legend:Fig 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/03/18 2016/03/21 rogid:+msMK6AgZ+aJt0cpuIV7g6JtWr4559292 rogid:tVQiqr2rPrfXb1Wb/2XUOTBBXIQ559292 rigid:aiD+5PyCVug+doNtNHVVgpUQKio false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25638 uniprotkb:P38768 intact:EBI-21956|uniprotkb:D6VR65|ensemblfungi:YCR060W intact:EBI-24499|uniprotkb:D3DKY1|ensemblfungi:YHR034C psi-mi:tah1_yeast(display_long)|uniprotkb:YCR60W(orf name)|uniprotkb:YCR060W(locus name)|uniprotkb:TAH1(gene name)|psi-mi:TAH1(display_short) psi-mi:pih1_yeast(display_long)|uniprotkb:PIH1(gene name)|psi-mi:PIH1(display_short)|uniprotkb:NOP17(gene name synonym)|uniprotkb:Nucleolar protein 17(gene name synonym)|uniprotkb:YHR034C(locus name) psi-mi:"MI:0018"(two hybrid) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11660963|imex:IM-25111-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009986.1|sgd:S000000656|mint:P25638|dip:DIP-5000N|ensemblfungi:YCR060W(gene)|ensemblfungi:YCR060W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051087"(chaperone binding)|go:"GO:0097255"(R2TP complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:2L6J|rcsb pdb:2LSU|rcsb pdb:2LSV|rcsb pdb:2MNJ|rcsb pdb:4CGQ|rcsb pdb:4CGU refseq:NP_011899.1|sgd:S000001076|dip:DIP-807N|mint:P38768|ensemblfungi:YHR034C(gene)|ensemblfungi:YHR034C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008380"(RNA splicing)|go:"GO:0097255"(R2TP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012981(Nop17p)|interpro:IPR041441|rcsb pdb:2MNJ|rcsb pdb:4CGU|rcsb pdb:4CHH - crc64:3738DE6F227F803A crc64:02C06D0A113B1B3B figure legend:Fig 1 C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/03/18 2016/03/21 rogid:DXXWcBPtKzTtK2Hp7l4g0ukIZPQ559292 rogid:5z/tmH0iorWwa2yX80ZUuQAZEQw559292 rigid:VBUdaJGGLRcprUaaxewhH3RKeJg false - mutation disrupting interaction:306-306 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12499 uniprotkb:P38768 intact:EBI-12126|uniprotkb:D6W309|ensemblfungi:YOR310C intact:EBI-24499|uniprotkb:D3DKY1|ensemblfungi:YHR034C psi-mi:nop58_yeast(display_long)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOP5(gene name synonym)|uniprotkb:YOR310C(locus name)|uniprotkb:O6108(orf name) psi-mi:pih1_yeast(display_long)|uniprotkb:PIH1(gene name)|psi-mi:PIH1(display_short)|uniprotkb:NOP17(gene name synonym)|uniprotkb:Nucleolar protein 17(gene name synonym)|uniprotkb:YHR034C(locus name) psi-mi:"MI:0018"(two hybrid) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11664110|imex:IM-25111-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR310C(gene)|ensemblfungi:YOR310C_mRNA(transcript)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0017069"(snRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-4570464|reactome:R-SCE-6791226|rcsb pdb:6ZQC|refseq:NP_014955.1|sgd:S000005837|dip:DIP-5843N|mint:Q12499 refseq:NP_011899.1|sgd:S000001076|dip:DIP-807N|mint:P38768|ensemblfungi:YHR034C(gene)|ensemblfungi:YHR034C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008380"(RNA splicing)|go:"GO:0097255"(R2TP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012981(Nop17p)|interpro:IPR041441|rcsb pdb:2MNJ|rcsb pdb:4CGU|rcsb pdb:4CHH - crc64:8A2889448B2A19E2 crc64:02C06D0A113B1B3B figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/03/18 2016/03/21 rogid:Dtk1A6GOVO3KgTak8cTHjO+eDQ4559292 rogid:5z/tmH0iorWwa2yX80ZUuQAZEQw559292 rigid:DCZTgb3NggktqIeGdhZtIesmWHM false sufficient binding region:324-511 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03940 uniprotkb:P38768 intact:EBI-30712|uniprotkb:D6VSH3|ensemblfungi:YDR190C intact:EBI-24499|uniprotkb:D3DKY1|ensemblfungi:YHR034C psi-mi:ruvb1_yeast(display_long)|uniprotkb:RVB1(gene name)|psi-mi:RVB1(display_short)|uniprotkb:TIP49-homology protein 1(gene name synonym)|uniprotkb:TIP49a homolog(gene name synonym)|uniprotkb:TIH1(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:YDR190C(locus name) psi-mi:pih1_yeast(display_long)|uniprotkb:PIH1(gene name)|psi-mi:PIH1(display_short)|uniprotkb:NOP17(gene name synonym)|uniprotkb:Nucleolar protein 17(gene name synonym)|uniprotkb:YHR034C(locus name) psi-mi:"MI:0096"(pull down) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11661015|imex:IM-25111-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010476.1|sgd:S000002598|dip:DIP-4896N|mint:Q03940|ensemblfungi:YDR190C(gene)|ensemblfungi:YDR190C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0070209"(ASTRA complex)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|rcsb pdb:6GEJ|rcsb pdb:6GEN|reactome:R-SCE-5689880 refseq:NP_011899.1|sgd:S000001076|dip:DIP-807N|mint:P38768|ensemblfungi:YHR034C(gene)|ensemblfungi:YHR034C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008380"(RNA splicing)|go:"GO:0097255"(R2TP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012981(Nop17p)|interpro:IPR041441|rcsb pdb:2MNJ|rcsb pdb:4CGU|rcsb pdb:4CHH - crc64:93D6ECB7006AF0F2 crc64:02C06D0A113B1B3B figure legend:Fig1B|antagonist:"CHEBI:15422 -ATP"|antagonist:"CHEBI:16761 -ADP"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/03/18 2016/04/06 rogid:tVQiqr2rPrfXb1Wb/2XUOTBBXIQ559292 rogid:5z/tmH0iorWwa2yX80ZUuQAZEQw559292 rigid:lwmdz7iQ5sC6UDYFSHwRaLTd98A false his tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q12464 uniprotkb:P38768 intact:EBI-31814|uniprotkb:D6W3D5|ensemblfungi:YPL235W intact:EBI-24499|uniprotkb:D3DKY1|ensemblfungi:YHR034C psi-mi:ruvb2_yeast(display_long)|uniprotkb:TIP49-homology protein 2(gene name synonym)|uniprotkb:TIP49b homolog(gene name synonym)|uniprotkb:RVB2(gene name)|psi-mi:RVB2(display_short)|uniprotkb:TIH2(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:YPL235W(locus name)|uniprotkb:P1060(orf name) psi-mi:pih1_yeast(display_long)|uniprotkb:PIH1(gene name)|psi-mi:PIH1(display_short)|uniprotkb:NOP17(gene name synonym)|uniprotkb:Nucleolar protein 17(gene name synonym)|uniprotkb:YHR034C(locus name) psi-mi:"MI:0096"(pull down) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11662118|imex:IM-25111-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015089.1|sgd:S000006156|dip:DIP-5207N|mint:Q12464|ensemblfungi:YPL235W(gene)|ensemblfungi:YPL235W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0070209"(ASTRA complex)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|rcsb pdb:5OUN|rcsb pdb:6GEJ|rcsb pdb:6GEN refseq:NP_011899.1|sgd:S000001076|dip:DIP-807N|mint:P38768|ensemblfungi:YHR034C(gene)|ensemblfungi:YHR034C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008380"(RNA splicing)|go:"GO:0097255"(R2TP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012981(Nop17p)|interpro:IPR041441|rcsb pdb:2MNJ|rcsb pdb:4CGU|rcsb pdb:4CHH - crc64:0D8EFBA7EC711AB8 crc64:02C06D0A113B1B3B figure legend:Fig1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/03/18 2016/04/06 rogid:+msMK6AgZ+aJt0cpuIV7g6JtWr4559292 rogid:5z/tmH0iorWwa2yX80ZUuQAZEQw559292 rigid:cIvs5NMek0tMcrT3DgLr0l72dz8 false his tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P15646 uniprotkb:P39990 intact:EBI-6838|uniprotkb:P89890|uniprotkb:D6VRX5|ensemblfungi:YDL014W intact:EBI-12032|ensemblfungi:YEL026W|uniprotkb:D3DLM2 psi-mi:fbrl_yeast(display_long)|uniprotkb:NOP1(gene name)|psi-mi:NOP1(display_short)|uniprotkb:LOT3(gene name synonym)|uniprotkb:YDL014W(locus name)|uniprotkb:D2870(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein NOP1(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym) psi-mi:snu13_yeast(display_long)|uniprotkb:YEL026W(locus name)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:Small nuclear ribonucleoprotein-associated protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11664012|imex:IM-25111-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010270.1|sgd:S000002172|mint:P15646|dip:DIP-698N|ensemblfungi:YDL014W(gene)|ensemblfungi:YDL014W_mRNA(transcript)|go:"GO:0000451"(rRNA 2'-O-methylation)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006364"(rRNA processing)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0030686"(90S preribosome)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0043144"("sno(s)RNA processing")|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 ensemblfungi:YEL026W(gene)|ensemblfungi:YEL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1905216"(positive regulation of RNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:1ZWZ|rcsb pdb:2ALE|rcsb pdb:3JCM|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:4NUT|reactome:R-SCE-6791226|refseq:NP_010888.1|sgd:S000000752|mint:P39990|dip:DIP-2870N - crc64:56A8B958A7B6066E crc64:4489780153E8F182 figure legend:Fig 6 A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/03/18 2016/03/21 rogid:zc81RbHf8PxId/8oPXPD3/MpmBU559292 rogid:4C07wkvZ4Nts4Oxw4/L7QMkwcmE559292 rigid:A3Ap9NHCHyCKpAjAxo3CPLN/yqY false his tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P39990 uniprotkb:P38768 intact:EBI-12032|ensemblfungi:YEL026W|uniprotkb:D3DLM2 intact:EBI-24499|uniprotkb:D3DKY1|ensemblfungi:YHR034C psi-mi:snu13_yeast(display_long)|uniprotkb:YEL026W(locus name)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:Small nuclear ribonucleoprotein-associated protein 1(gene name synonym) psi-mi:pih1_yeast(display_long)|uniprotkb:PIH1(gene name)|psi-mi:PIH1(display_short)|uniprotkb:NOP17(gene name synonym)|uniprotkb:Nucleolar protein 17(gene name synonym)|uniprotkb:YHR034C(locus name) psi-mi:"MI:0096"(pull down) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11664067|imex:IM-25111-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YEL026W(gene)|ensemblfungi:YEL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1905216"(positive regulation of RNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:1ZWZ|rcsb pdb:2ALE|rcsb pdb:3JCM|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:4NUT|reactome:R-SCE-6791226|refseq:NP_010888.1|sgd:S000000752|mint:P39990|dip:DIP-2870N refseq:NP_011899.1|sgd:S000001076|dip:DIP-807N|mint:P38768|ensemblfungi:YHR034C(gene)|ensemblfungi:YHR034C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008380"(RNA splicing)|go:"GO:0097255"(R2TP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012981(Nop17p)|interpro:IPR041441|rcsb pdb:2MNJ|rcsb pdb:4CGU|rcsb pdb:4CHH - crc64:4489780153E8F182 crc64:02C06D0A113B1B3B figure legend:Fig 6 A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/03/18 2016/04/20 rogid:4C07wkvZ4Nts4Oxw4/L7QMkwcmE559292 rogid:5z/tmH0iorWwa2yX80ZUuQAZEQw559292 rigid:ltgvjgpib0ASMS5pODysQPK8vtQ false glutathione s tranferase tag:n-n his tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P39990 uniprotkb:P15646 intact:EBI-12032|ensemblfungi:YEL026W|uniprotkb:D3DLM2 intact:EBI-6838|uniprotkb:P89890|uniprotkb:D6VRX5|ensemblfungi:YDL014W psi-mi:snu13_yeast(display_long)|uniprotkb:YEL026W(locus name)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:Small nuclear ribonucleoprotein-associated protein 1(gene name synonym) psi-mi:fbrl_yeast(display_long)|uniprotkb:NOP1(gene name)|psi-mi:NOP1(display_short)|uniprotkb:LOT3(gene name synonym)|uniprotkb:YDL014W(locus name)|uniprotkb:D2870(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein NOP1(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym) psi-mi:"MI:0096"(pull down) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11664067|imex:IM-25111-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YEL026W(gene)|ensemblfungi:YEL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1905216"(positive regulation of RNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:1ZWZ|rcsb pdb:2ALE|rcsb pdb:3JCM|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:4NUT|reactome:R-SCE-6791226|refseq:NP_010888.1|sgd:S000000752|mint:P39990|dip:DIP-2870N refseq:NP_010270.1|sgd:S000002172|mint:P15646|dip:DIP-698N|ensemblfungi:YDL014W(gene)|ensemblfungi:YDL014W_mRNA(transcript)|go:"GO:0000451"(rRNA 2'-O-methylation)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006364"(rRNA processing)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0030686"(90S preribosome)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0043144"("sno(s)RNA processing")|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226 - crc64:4489780153E8F182 crc64:56A8B958A7B6066E figure legend:Fig 6 A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/03/18 2016/04/20 rogid:4C07wkvZ4Nts4Oxw4/L7QMkwcmE559292 rogid:zc81RbHf8PxId/8oPXPD3/MpmBU559292 rigid:ltgvjgpib0ASMS5pODysQPK8vtQ false glutathione s tranferase tag:n-n his tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q12499 intact:EBI-10821792 intact:EBI-12126|uniprotkb:D6W309|ensemblfungi:YOR310C rnacentral:URS0000444F9B_559292 psi-mi:nop58_yeast(display_long)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOP5(gene name synonym)|uniprotkb:YOR310C(locus name)|uniprotkb:O6108(orf name) psi-mi:snru3a yeast(display_short)|psi-mi:EBI-10821792(display_long) psi-mi:"MI:0004"(affinity chromatography technology) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11663958|imex:IM-25111-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0607"(small nuclear rna) ensemblfungi:YOR310C(gene)|ensemblfungi:YOR310C_mRNA(transcript)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0017069"(snRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-4570464|reactome:R-SCE-6791226|rcsb pdb:6ZQC|refseq:NP_014955.1|sgd:S000005837|dip:DIP-5843N|mint:Q12499 - - crc64:8A2889448B2A19E2 - figure legend:Fig 4, Fig 5B|comment:The interaction between U3 and Nop58 was increased in the presence of Nop17|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/03/18 2016/03/31 rogid:Dtk1A6GOVO3KgTak8cTHjO+eDQ4559292 - - false protein a tag:n-n - - - psi-mi:"MI:0929"(northern blot) psi-mi:"MI:0929"(northern blot) uniprotkb:Q12499 intact:EBI-10825186 intact:EBI-12126|uniprotkb:D6W309|ensemblfungi:YOR310C rnacentral:URS000055688D_559292 psi-mi:nop58_yeast(display_long)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOP5(gene name synonym)|uniprotkb:YOR310C(locus name)|uniprotkb:O6108(orf name) psi-mi:rrna 5s yeast(display_short)|psi-mi:EBI-10825186(display_long) psi-mi:"MI:0004"(affinity chromatography technology) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11663958|imex:IM-25111-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0608"(ribosomal rna) ensemblfungi:YOR310C(gene)|ensemblfungi:YOR310C_mRNA(transcript)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0017069"(snRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-4570464|reactome:R-SCE-6791226|rcsb pdb:6ZQC|refseq:NP_014955.1|sgd:S000005837|dip:DIP-5843N|mint:Q12499 - - crc64:8A2889448B2A19E2 - figure legend:Fig 4, Fig 5B|comment:The interaction between U3 and Nop58 was increased in the presence of Nop17|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/03/18 2016/03/31 rogid:Dtk1A6GOVO3KgTak8cTHjO+eDQ4559292 - - false protein a tag:n-n - - - psi-mi:"MI:0929"(northern blot) psi-mi:"MI:0929"(northern blot) intact:EBI-11687991 uniprotkb:Q12499 sgd:S000007294 intact:EBI-12126|uniprotkb:D6W309|ensemblfungi:YOR310C psi-mi:snr17a_yeast_gene(display_short)|psi-mi:EBI-11687991(display_long) psi-mi:nop58_yeast(display_long)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOP5(gene name synonym)|uniprotkb:YOR310C(locus name)|uniprotkb:O6108(orf name) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Prieto et al. (2014) imex:IM-25111|pubmed:25888478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11684915|imex:IM-25111-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - ensemblfungi:YOR310C(gene)|ensemblfungi:YOR310C_mRNA(transcript)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0017069"(snRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-4570464|reactome:R-SCE-6791226|rcsb pdb:6ZQC|refseq:NP_014955.1|sgd:S000005837|dip:DIP-5843N|mint:Q12499 - - crc64:8A2889448B2A19E2 figure legend:fig4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/03/18 2016/04/21 - rogid:Dtk1A6GOVO3KgTak8cTHjO+eDQ4559292 - false - protein a tag:n-n - - psi-mi:"MI:1196"(quantitative reverse transcription pcr) psi-mi:"MI:1196"(quantitative reverse transcription pcr)