#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P04004	uniprotkb:Q4KTX9	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218	intact:EBI-12501515	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:q4ktx9_haeif(display_long)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12501510|imex:IM-26237-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	-	-	-	figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2017/11/27	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:80-396|his tag:c-c	sufficient binding region:429-652|his tag:c-c|binding-associated region:1047-1751|sufficient binding region:1536-2031|sufficient binding region:265-376	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q4KTX9	uniprotkb:Q4KTX9	intact:EBI-12501515	intact:EBI-12501515	psi-mi:q4ktx9_haeif(display_long)	psi-mi:q4ktx9_haeif(display_long)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12501546|imex:IM-26237-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	-	-	-	figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2017/11/28	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:54-2300|his tag:c-c	sufficient binding region:54-608	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12501546|imex:IM-26237-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N	-	-	-	figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2017/11/28	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:54-2300|his tag:c-c	sufficient binding region:80-396|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P04004	uniprotkb:Q4KTX9	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218	intact:EBI-12501515	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:q4ktx9_haeif(display_long)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12511305|imex:IM-26237-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	-	-	-	figure legend:3F & 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2017/11/27	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	necessary binding region:352-374|his tag:c-c	sufficient binding region:54-2300|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P04004	uniprotkb:Q4KTX9	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218	intact:EBI-12501515	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:q4ktx9_haeif(display_long)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12511389|imex:IM-26237-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	-	-	-	figure legend:S3|comment:Multimeric Vn had a  higher Hsf-binding capacity than monomeric  Vn.|comment:Experiment for this interaction it not stated to be an ELISA, but probably is.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2016/08/22	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	his tag:c-c	sufficient binding region:54-2300|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P04004	uniprotkb:Q4KTX9	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218	intact:EBI-12501515	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:q4ktx9_haeif(display_long)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12513499|imex:IM-26237-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	-	-	-	figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2017/11/27	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	his tag:c-c	his tag:n-n	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P04004	uniprotkb:Q4KTX9	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218	intact:EBI-12501515	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:q4ktx9_haeif(display_long)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-16631450|imex:IM-26237-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	-	-	-	figure legend:2C and 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2017/11/27	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:80-396|his tag:c-c	sufficient binding region:54-2300|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
chebi:"CHEBI:28304"	uniprotkb:Q4KTX9	intact:EBI-1379423	intact:EBI-12501515	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:q4ktx9_haeif(display_long)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-16631467|imex:IM-26237-22	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	-	-	-	figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2017/11/27	-	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	-	false	-	sufficient binding region:54-2300|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-16631467|imex:IM-26237-22	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N	-	-	-	figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2017/11/27	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	-	false	sufficient binding region:54-2300|his tag:c-c	sufficient binding region:80-396|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q4KTX9	uniprotkb:Q4KTX9	intact:EBI-12501515	intact:EBI-12501515	psi-mi:q4ktx9_haeif(display_long)	psi-mi:q4ktx9_haeif(display_long)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-16631480|imex:IM-26237-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	-	-	-	figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2017/11/28	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:54-2300|his tag:c-c	sufficient binding region:54-2300	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-16631480|imex:IM-26237-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N	-	-	-	figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2017/11/28	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:54-2300|his tag:c-c	sufficient binding region:80-396|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q4KTX9	uniprotkb:Q4KTX9	intact:EBI-12501515	intact:EBI-12501515	psi-mi:q4ktx9_haeif(display_long)	psi-mi:q4ktx9_haeif(display_long)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-16631495|imex:IM-26237-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	-	-	-	figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2017/11/28	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:54-2300|his tag:c-c	sufficient binding region:429-652	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-16631495|imex:IM-26237-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N	-	-	-	figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2017/11/28	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:54-2300|his tag:c-c	sufficient binding region:80-396|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P04004	uniprotkb:Q4KTX9	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218	intact:EBI-12501515	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:q4ktx9_haeif(display_long)	psi-mi:"MI:0107"(surface plasmon resonance)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12501572|imex:IM-26237-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	-	-	-	figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.39x10^-8(molar)	2016/08/09	2017/11/27	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:80-396|his tag:c-c	sufficient binding region:54-2300|his tag:c-c	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04004	uniprotkb:Q4KTX9	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218	intact:EBI-12501515	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:q4ktx9_haeif(display_long)	psi-mi:"MI:0107"(surface plasmon resonance)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12501582|imex:IM-26237-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	-	-	-	figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.58x10^-8(molar)	2016/08/09	2017/11/27	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:80-396|his tag:c-c	sufficient binding region:429-652|his tag:c-c	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04004	uniprotkb:Q4KTX9	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218	intact:EBI-12501515	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:q4ktx9_haeif(display_long)	psi-mi:"MI:0054"(fluorescence-activated cell sorting)	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12511425|imex:IM-26237-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N	go:"GO:0009279"(cell outer membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174	-	-	-	figure legend:S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2016/08/25	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	-	his tag:n-n	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)