#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q14094 uniprotkb:Q00536 intact:EBI-1104653|ensembl:ENSP00000237654|uniprotkb:B7Z6X4|uniprotkb:B2R6M0 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:ccni_human(display_long)|uniprotkb:CCNI(gene name)|psi-mi:CCNI(display_short) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615332|imex:IM-25032-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006826.1|ensembl:ENSG00000118816(gene)|ensembl:ENST00000237654(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044772"(mitotic cell cycle phase transition)|interpro:IPR013763(Cyclin-related)|interpro:IPR028856|interpro:IPR036915|interpro:IPR039361|interpro:IPR006671(Cyclin, N-terminal)|refseq:NP_001335061.1|refseq:NP_001335062.1|refseq:NP_001335063.1 refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/02/26 2016/02/26 rogid:lsO+Zg9Xf/S6JoMy7kmo4IT9Nts9606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:QveUHb6KJiGHqgjQ1JxpHr3B5HY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75909 uniprotkb:Q00536 intact:EBI-739806|uniprotkb:Q96B63|uniprotkb:Q9NNY9|uniprotkb:Q59FT6|uniprotkb:Q86U16|ensembl:ENSP00000374529 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:ccnk_human(display_long)|uniprotkb:CCNK(gene name)|psi-mi:CCNK(display_short)|uniprotkb:CPR4(gene name synonym) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615337|imex:IM-25032-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001092872.1|ensembl:ENSG00000090061(gene)|ensembl:ENST00000389879(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0002944"(cyclin K-CDK12 complex)|go:"GO:0002945"(cyclin K-CDK13 complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|rcsb pdb:2I53|rcsb pdb:4CXA|rcsb pdb:4NST|rcsb pdb:4UN0|rcsb pdb:5ACB|rcsb pdb:5EFQ|rcsb pdb:6B3E|rcsb pdb:6CKX|rcsb pdb:6TD3|rcsb pdb:7NXJ|rcsb pdb:7NXK|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|refseq:XP_005268211.1|refseq:XP_011535577.1|dip:DIP-50081N refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/02/26 2016/02/26 rogid:GwKOLtYbHmvvuRXSwfW4pffSDpE9606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:I+tvVgdyNiMSBVVn/qVOzs6DgSI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8ND76 uniprotkb:Q00536 intact:EBI-1049189|uniprotkb:Q2M3V4|uniprotkb:Q2TU96|uniprotkb:Q6NT86|uniprotkb:Q7Z4U7|uniprotkb:Q8TEX2|uniprotkb:Q8TEX3|uniprotkb:Q96M99|uniprotkb:Q96P45|uniprotkb:B7ZKX9|uniprotkb:D3DRY9|ensembl:ENSP00000363836 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:ccny_human(display_long)|uniprotkb:Cyclin fold protein 1(gene name synonym)|uniprotkb:Cyclin box protein 1(gene name synonym)|uniprotkb:CCNY(gene name)|psi-mi:CCNY(display_short)|uniprotkb:C10orf9(gene name synonym)|uniprotkb:CBCP1(gene name synonym)|uniprotkb:CFP1(gene name synonym)|uniprotkb:cyclin-X(gene name synonym) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615342|imex:IM-25032-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659449.3|refseq:NP_859049.2|refseq:NP_001269781.1|refseq:NP_001269782.1|refseq:NP_001269783.1|refseq:XP_011517660.1|refseq:XP_011517662.1|refseq:XP_011517663.1|refseq:XP_011517664.1|refseq:XP_011517665.1|refseq:XP_011517666.1|refseq:XP_011517667.1|refseq:XP_011517668.1|refseq:XP_011517669.1|refseq:XP_011517670.1|refseq:XP_016871328.1|refseq:XP_016871329.1|refseq:XP_016871330.1|ensembl:ENSG00000108100(gene)|ensembl:ENST00000374704(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000308"(cytoplasmic cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR012399(Uncharacterised conserved protein CG14939, cyclin region)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|mint:Q8ND76 refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/02/26 2016/02/26 rogid:HilQRrRscMCl9sjGletD/fYyTI89606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:eAwa9eMl+2fVz4LQlo86RHLOzDc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N7R7 uniprotkb:Q00536 intact:EBI-10103094|uniprotkb:Q6NX60|ensembl:ENSP00000295414 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:ccyl1_human(display_long)|uniprotkb:CCNYL1(gene name)|psi-mi:CCNYL1(display_short) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615347|imex:IM-25032-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135772.1|refseq:NP_689736.1|ensembl:ENSG00000163249(gene)|ensembl:ENST00000295414(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR012399(Uncharacterised conserved protein CG14939, cyclin region)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|refseq:NP_001317147.1 refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/02/26 2016/02/26 rogid:PA78awP4glVJu4c+J2tUBdr6uPQ9606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:M1ES1rXKC1tyNricdd3S6a8Gy1I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5MJ70 uniprotkb:Q00536 intact:EBI-7125479|ensembl:ENSP00000335628|ensembl:ENSP00000368898|uniprotkb:Q53R05|uniprotkb:Q5MJ69|intact:MINT-7226374 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:spdya_human(display_long)|uniprotkb:SPDYA(gene name)|psi-mi:SPDYA(display_short)|uniprotkb:SPDY1(gene name synonym)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Speedy-1(gene name synonym)|uniprotkb:Rapid inducer of G2/M progression in oocytes A(gene name synonym) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615362|imex:IM-25032-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|interpro:IPR020984|mint:Q5MJ70|rcsb pdb:5UQ1|rcsb pdb:5UQ2|rcsb pdb:5UQ3|rcsb pdb:7E34|ensembl:ENSG00000163806(gene)|ensembl:ENST00000334056(transcript)|ensembl:ENST00000379579(transcript)|refseq:NP_877433.2|refseq:NP_001136106.1|refseq:NP_001008779.1 refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - comment:mint - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/02/26 2016/02/26 rogid:n/OYB/DuWzjOFsJeW00hzAz3zbM9606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:RqtXsbC6etsIP5KsphQTIith6L4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NRD0 uniprotkb:Q00536 intact:EBI-11615366|uniprotkb:B2RB40|uniprotkb:D3DP41|uniprotkb:G5E9Z0|uniprotkb:Q6UWN4|uniprotkb:Q8IWE1|uniprotkb:Q9NRP5|uniprotkb:Q9UKC4|ensembl:ENSP00000377280 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:fbx8_human(display_long)|uniprotkb:FBXO8(gene name)|psi-mi:FBXO8(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBX8(gene name synonym)|uniprotkb:DC10(orf name)|uniprotkb:UNQ1877/PRO4320(orf name)|uniprotkb:F-box/SEC7 protein FBS(gene name synonym) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615399|imex:IM-25032-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036312.2|ensembl:ENSG00000164117(gene)|ensembl:ENST00000393674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR023394|interpro:IPR035999|interpro:IPR036047 refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/02/26 2016/02/26 rogid:iw1wQu/WnQC2vnge/KH840EAPr89606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:ea3iaHW+bYkrDxWyRAo6FZ3Ex80 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A9UHW6 uniprotkb:Q00536 intact:EBI-373498|uniprotkb:Q8N4Q5|intact:EBI-946774|uniprotkb:B4DUM7|uniprotkb:Q9HBL5|ensembl:ENSP00000321625|ensembl:ENSP00000484245 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:mi4gd_human(display_long)|uniprotkb:SLIP1(gene name synonym)|uniprotkb:SLBP-interacting protein 1(gene name synonym)|uniprotkb:MIF4GD(gene name)|psi-mi:MIF4GD(display_short) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615403|imex:IM-25032-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125457(gene)|ensembl:ENST00000325102(transcript)|ensembl:ENST00000618645(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008494"(translation activator activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|mint:A9UHW6|refseq:NP_001229427.1|refseq:NP_001229429.1|refseq:NP_001229430.1|refseq:NP_065730.2|refseq:XP_005257589.1|refseq:XP_005257590.1|refseq:XP_016880382.1|refseq:XP_016880383.1|refseq:XP_005257587.1 refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/02/26 2016/02/26 rogid:fVJrdaWCxDp4EBdc1QyA0lECSGE9606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:kolFHBh5J5rOLzqj02ycUkDoIpw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6ZVT6 uniprotkb:Q00536 intact:EBI-11615407|uniprotkb:B9EKV6|uniprotkb:Q6ZV69 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:cf20d_human(display_long)|uniprotkb:CFAP20DC(gene name)|psi-mi:CFAP20DC(display_short)|uniprotkb:C3orf67(gene name synonym)|uniprotkb:Uncharacterized protein C3orf67(gene name synonym) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615425|imex:IM-25032-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940865.1|refseq:XP_011531758.1|refseq:XP_011531759.1|refseq:XP_011531760.1|interpro:IPR030467|interpro:IPR007714(Protein of unknown function DUF667)|interpro:IPR040441 refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/02/26 2016/02/26 rogid:RxLyUgN5h4+Mgu5KMo1pZ+diYzQ9606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:pwipSf8GETy81mmq+ECfDDjJq2M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03393 uniprotkb:Q00536 intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615429|imex:IM-25032-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151 refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/02/26 2016/02/26 rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:P1heHRfR1nGRGiVpg5g7SfCBOGQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N816 uniprotkb:Q00536 intact:EBI-11615433|uniprotkb:B4DQ34|uniprotkb:Q96BP9 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:tmm99_human(display_long)|uniprotkb:KRT10-AS1(gene name)|psi-mi:KRT10-AS1(display_short)|uniprotkb:TMEM99(gene name synonym)|uniprotkb:Transmembrane protein 99(gene name synonym) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615451|imex:IM-25032-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001182315.1|refseq:NP_001182316.1|refseq:NP_660317.2|refseq:XP_005257146.1|go:"GO:0016021"(integral component of membrane)|refseq:XP_016879742.1 refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/02/26 2016/02/26 rogid:2OxPqELrB0ko7989QAzKoH5eZLg9606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:P6nllElZxnorVkLlNbDzcoY2kSk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16222 uniprotkb:Q00536 intact:EBI-10237564|uniprotkb:Q5VTB0|uniprotkb:Q5VTA9|uniprotkb:B2R6R8|uniprotkb:Q96GM2|uniprotkb:Q5VTB1|ensembl:ENSP00000271469|ensembl:ENSP00000356902 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:uap1_human(display_long)|uniprotkb:UAP1(gene name)|psi-mi:UAP1(display_short)|uniprotkb:Antigen X(gene name synonym)|uniprotkb:SPAG2(gene name synonym)|uniprotkb:Sperm-associated antigen 2(gene name synonym) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615455|imex:IM-25032-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001311042.1|refseq:NP_001311043.1|refseq:NP_001311044.1|refseq:NP_001311045.1|refseq:NP_001311046.1|refseq:NP_003106.3|refseq:XP_011508215.1|refseq:XP_011508216.1|ensembl:ENSG00000117143(gene)|ensembl:ENST00000271469(transcript)|ensembl:ENST00000367925(transcript)|go:"GO:0003977"(UDP-N-acetylglucosamine diphosphorylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0052630"(UDP-N-acetylgalactosamine diphosphorylase activity)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR029044|interpro:IPR039741|rcsb pdb:1JV1|rcsb pdb:1JV3|rcsb pdb:1JVD|rcsb pdb:1JVG|rcsb pdb:6Z2F|reactome:R-HSA-446210 refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/02/26 2016/02/26 rogid:E9VKe3V7wF1ZoUYkQtOucXnlu6w9606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:TzxIXFscgeSUf5L09GzvPXPY7mo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8ND76-1 uniprotkb:Q00536 intact:EBI-11615526|ensembl:ENSP00000363836 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:q8nd76-1(display_long)|uniprotkb:Cyclin box protein 1(gene name synonym)|uniprotkb:Cyclin fold protein 1(gene name synonym)|uniprotkb:cyclin-X(gene name synonym)|uniprotkb:b(isoform synonym)|uniprotkb:CCNY(gene name)|psi-mi:CCNY(display_short)|uniprotkb:C10orf9(gene name synonym)|uniprotkb:CBCP1(gene name synonym)|uniprotkb:CFP1(gene name synonym) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615466|imex:IM-25032-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1049189(isoform-parent)|ensembl:ENSG00000108100(gene)|ensembl:ENST00000374704(transcript) refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 intact:EBI-11620018(see-also) - - figure legend:Fig. 1B, 1C, 2C, 2D, 2E, 3B, 6D, 7A|agonist:"Staurosporine (CHEBI:15738)"|antagonist:"Forskolin (CHEBI:42471)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2016/02/26 2016/02/26 rogid:HilQRrRscMCl9sjGletD/fYyTI89606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:eAwa9eMl+2fVz4LQlo86RHLOzDc false necessary binding region:1-54|yellow fluorescent protein tag:n-n|mutation decreasing interaction strength:222-224 flag tag:n-n|necessary binding region:106-121|sufficient binding region:106-476|necessary binding region:461-476|mutation disrupting interaction strength:119-119|mutation increasing interaction strength:153-153|mutation disrupting interaction strength:153-153|mutation disrupting interaction strength:158-158|mutation disrupting interaction strength:209-209|mutation disrupting interaction strength:216-216|O-phospho-L-serine:153-153 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8ND76-1 uniprotkb:Q00536 intact:EBI-11615526|ensembl:ENSP00000363836 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:q8nd76-1(display_long)|uniprotkb:Cyclin box protein 1(gene name synonym)|uniprotkb:Cyclin fold protein 1(gene name synonym)|uniprotkb:cyclin-X(gene name synonym)|uniprotkb:b(isoform synonym)|uniprotkb:CCNY(gene name)|psi-mi:CCNY(display_short)|uniprotkb:C10orf9(gene name synonym)|uniprotkb:CBCP1(gene name synonym)|uniprotkb:CFP1(gene name synonym) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615474|imex:IM-25032-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1049189(isoform-parent)|ensembl:ENSG00000108100(gene)|ensembl:ENST00000374704(transcript) refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - - - figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2016/02/26 2016/02/26 rogid:HilQRrRscMCl9sjGletD/fYyTI89606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:eAwa9eMl+2fVz4LQlo86RHLOzDc false binding-associated region:1-54|yellow fluorescent protein tag:n-n|sufficient binding region:1-320|mutation disrupting interaction strength:222-224 flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8ND76-1 uniprotkb:Q00536 intact:EBI-11615526|ensembl:ENSP00000363836 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:q8nd76-1(display_long)|uniprotkb:Cyclin box protein 1(gene name synonym)|uniprotkb:Cyclin fold protein 1(gene name synonym)|uniprotkb:cyclin-X(gene name synonym)|uniprotkb:b(isoform synonym)|uniprotkb:CCNY(gene name)|psi-mi:CCNY(display_short)|uniprotkb:C10orf9(gene name synonym)|uniprotkb:CBCP1(gene name synonym)|uniprotkb:CFP1(gene name synonym) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615500|imex:IM-25032-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1049189(isoform-parent)|ensembl:ENSG00000108100(gene)|ensembl:ENST00000374704(transcript) refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 intact:EBI-11615543(see-also) - - figure legend:Fig. 1B, 1C, 2C, 2D, 2E.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2016/02/26 2016/02/26 rogid:HilQRrRscMCl9sjGletD/fYyTI89606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:eAwa9eMl+2fVz4LQlo86RHLOzDc false yellow fluorescent protein tag:n-n flag tag:n-n|necessary binding region:106-121|sufficient binding region:106-476|necessary binding region:461-476|mutation disrupting interaction strength:119-119|mutation increasing interaction strength:153-153|mutation disrupting interaction strength:153-153|mutation disrupting interaction strength:158-158|mutation disrupting interaction strength:209-209|mutation disrupting interaction strength:216-216 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8ND76-1 uniprotkb:Q00536 intact:EBI-11615526|ensembl:ENSP00000363836 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:q8nd76-1(display_long)|uniprotkb:Cyclin box protein 1(gene name synonym)|uniprotkb:Cyclin fold protein 1(gene name synonym)|uniprotkb:cyclin-X(gene name synonym)|uniprotkb:b(isoform synonym)|uniprotkb:CCNY(gene name)|psi-mi:CCNY(display_short)|uniprotkb:C10orf9(gene name synonym)|uniprotkb:CBCP1(gene name synonym)|uniprotkb:CFP1(gene name synonym) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615570|imex:IM-25032-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1049189(isoform-parent)|ensembl:ENSG00000108100(gene)|ensembl:ENST00000374704(transcript) refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - - - figure legend:Fig. 6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2016/02/26 2016/02/26 rogid:HilQRrRscMCl9sjGletD/fYyTI89606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:eAwa9eMl+2fVz4LQlo86RHLOzDc false flag tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8ND76-1 uniprotkb:Q00536 intact:EBI-11615526|ensembl:ENSP00000363836 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:q8nd76-1(display_long)|uniprotkb:Cyclin box protein 1(gene name synonym)|uniprotkb:Cyclin fold protein 1(gene name synonym)|uniprotkb:cyclin-X(gene name synonym)|uniprotkb:b(isoform synonym)|uniprotkb:CCNY(gene name)|psi-mi:CCNY(display_short)|uniprotkb:C10orf9(gene name synonym)|uniprotkb:CBCP1(gene name synonym)|uniprotkb:CFP1(gene name synonym) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11620000|imex:IM-25032-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1049189(isoform-parent)|ensembl:ENSG00000108100(gene)|ensembl:ENST00000374704(transcript) refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2016/02/26 2016/03/08 rogid:HilQRrRscMCl9sjGletD/fYyTI89606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:eAwa9eMl+2fVz4LQlo86RHLOzDc false yellow fluorescent protein tag:c-c flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q00536 uniprotkb:Q8ND76-1 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 intact:EBI-11615526|ensembl:ENSP00000363836 psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:q8nd76-1(display_long)|uniprotkb:Cyclin box protein 1(gene name synonym)|uniprotkb:Cyclin fold protein 1(gene name synonym)|uniprotkb:cyclin-X(gene name synonym)|uniprotkb:b(isoform synonym)|uniprotkb:CCNY(gene name)|psi-mi:CCNY(display_short)|uniprotkb:C10orf9(gene name synonym)|uniprotkb:CBCP1(gene name synonym)|uniprotkb:CFP1(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11615591|imex:IM-25032-31 - - psi-mi:"MI:0898"(putative self) psi-mi:"MI:1343"(enzyme regulator) psi-mi:"MI:0898"(putative self) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 intact:EBI-1049189(isoform-parent)|ensembl:ENSG00000108100(gene)|ensembl:ENST00000374704(transcript) go:"GO:0004672"(protein kinase activity) - - figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/26 2016/03/08 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rogid:HilQRrRscMCl9sjGletD/fYyTI89606 rigid:eAwa9eMl+2fVz4LQlo86RHLOzDc false sufficient binding region:107-496|his tag:?-?|mutation:153-153 maltose binding protein tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q00536 uniprotkb:Q8ND76-1 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 intact:EBI-11615526|ensembl:ENSP00000363836 psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:q8nd76-1(display_long)|uniprotkb:Cyclin box protein 1(gene name synonym)|uniprotkb:Cyclin fold protein 1(gene name synonym)|uniprotkb:cyclin-X(gene name synonym)|uniprotkb:b(isoform synonym)|uniprotkb:CCNY(gene name)|psi-mi:CCNY(display_short)|uniprotkb:C10orf9(gene name synonym)|uniprotkb:CBCP1(gene name synonym)|uniprotkb:CFP1(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11615614|imex:IM-25032-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:1343"(enzyme regulator) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 intact:EBI-1049189(isoform-parent)|ensembl:ENSG00000108100(gene)|ensembl:ENST00000374704(transcript) go:"GO:0004672"(protein kinase activity) - - figure legend:Fig. 7Bi|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/26 2016/03/08 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rogid:HilQRrRscMCl9sjGletD/fYyTI89606 rigid:eAwa9eMl+2fVz4LQlo86RHLOzDc false sufficient binding region:107-496|his tag:?-?|mutation:153-153 maltose binding protein tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q00536 uniprotkb:Q8ND76-1 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 intact:EBI-11615526|ensembl:ENSP00000363836 psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:q8nd76-1(display_long)|uniprotkb:Cyclin box protein 1(gene name synonym)|uniprotkb:Cyclin fold protein 1(gene name synonym)|uniprotkb:cyclin-X(gene name synonym)|uniprotkb:b(isoform synonym)|uniprotkb:CCNY(gene name)|psi-mi:CCNY(display_short)|uniprotkb:C10orf9(gene name synonym)|uniprotkb:CBCP1(gene name synonym)|uniprotkb:CFP1(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11615614|imex:IM-25032-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 intact:EBI-1049189(isoform-parent)|ensembl:ENSG00000108100(gene)|ensembl:ENST00000374704(transcript) go:"GO:0004672"(protein kinase activity) - - figure legend:Fig. 7Bi|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/26 2016/03/08 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rogid:HilQRrRscMCl9sjGletD/fYyTI89606 rigid:eAwa9eMl+2fVz4LQlo86RHLOzDc false sufficient binding region:107-496|his tag:?-?|mutation:153-153 maltose binding protein tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q04735 uniprotkb:Q8BGU5 intact:EBI-11615670|ensembl:ENSMUSP00000033380 intact:EBI-772904|uniprotkb:Q8CI87|uniprotkb:Q9CYN5|ensembl:ENSMUSP00000050001 psi-mi:cdk16_mouse(display_long)|uniprotkb:CRK5(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cdk16(gene name)|psi-mi:Cdk16(display_short)|uniprotkb:Crk5(gene name synonym)|uniprotkb:Pctaire1(gene name synonym)|uniprotkb:Pctk1(gene name synonym) psi-mi:ccny_mouse(display_long)|uniprotkb:Cyclin fold protein 1(gene name synonym)|uniprotkb:Ccny(gene name)|psi-mi:Ccny(display_short)|uniprotkb:Cfp1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615668|imex:IM-25032-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001297385.1|refseq:NP_035179.1|refseq:XP_006527633.1|ensembl:ENSMUSG00000031065(gene)|ensembl:ENSMUST00000033380(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) refseq:NP_080760.2|ensembl:ENSMUSG00000024286(gene)|ensembl:ENSMUST00000053917(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000308"(cytoplasmic cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR012399(Uncharacterised conserved protein CG14939, cyclin region)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|mint:Q8BGU5 - - - figure legend:Fig. 8C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2016/02/26 2016/02/26 rogid:IKtGg8vKACWQ8wChXgdVtoHGKlU10090 rogid:Ngxe55AQU1MZAYMVF8jtHDSyMPI10090 rigid:Qmmuq6uIQDzbn9/Bz3tAxX4qWLM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q04735 uniprotkb:Q8BGU5 intact:EBI-11615670|ensembl:ENSMUSP00000033380 intact:EBI-772904|uniprotkb:Q8CI87|uniprotkb:Q9CYN5|ensembl:ENSMUSP00000050001 psi-mi:cdk16_mouse(display_long)|uniprotkb:CRK5(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cdk16(gene name)|psi-mi:Cdk16(display_short)|uniprotkb:Crk5(gene name synonym)|uniprotkb:Pctaire1(gene name synonym)|uniprotkb:Pctk1(gene name synonym) psi-mi:ccny_mouse(display_long)|uniprotkb:Cyclin fold protein 1(gene name synonym)|uniprotkb:Ccny(gene name)|psi-mi:Ccny(display_short)|uniprotkb:Cfp1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mikolcevic et al. (2012) imex:IM-25032|pubmed:22184064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11615716|imex:IM-25032-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001297385.1|refseq:NP_035179.1|refseq:XP_006527633.1|ensembl:ENSMUSG00000031065(gene)|ensembl:ENSMUST00000033380(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) refseq:NP_080760.2|ensembl:ENSMUSG00000024286(gene)|ensembl:ENSMUST00000053917(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000308"(cytoplasmic cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR012399(Uncharacterised conserved protein CG14939, cyclin region)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|mint:Q8BGU5 - - - figure legend:Fig. 8C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2016/02/26 2016/02/26 rogid:IKtGg8vKACWQ8wChXgdVtoHGKlU10090 rogid:Ngxe55AQU1MZAYMVF8jtHDSyMPI10090 rigid:Qmmuq6uIQDzbn9/Bz3tAxX4qWLM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)