#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O00165 uniprotkb:Q68871 intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002 intact:EBI-12522528 psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym) psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Johns et al. (2010) pubmed:20631090|imex:IM-26141 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-12518818|imex:IM-26141-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165 go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128 - - - figure legend:results|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/09/13 2016/10/27 rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606 rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769 rigid:4tPnBcpvqfZUtw4JnTwz6GH+/IA false - binding-associated region:1..1-168..168 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O00165 uniprotkb:Q68871 intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002 intact:EBI-12522528 psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym) psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Johns et al. (2010) pubmed:20631090|imex:IM-26141 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-12518910|imex:IM-26141-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165 go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128 - - - figure legend:1A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/09/13 2016/10/27 rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606 rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769 rigid:4tPnBcpvqfZUtw4JnTwz6GH+/IA false - binding-associated region:1..1-168..168 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00165 uniprotkb:Q68871 intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002 intact:EBI-12522528 psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym) psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym) psi-mi:"MI:0096"(pull down) Johns et al. (2010) pubmed:20631090|imex:IM-26141 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-12518971|imex:IM-26141-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165 go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128 - - - figure legend:1B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9823(pig-max)|taxid:9823(Max kidney cell line) - 2016/09/13 2016/10/27 rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606 rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769 rigid:4tPnBcpvqfZUtw4JnTwz6GH+/IA false - glutathione s tranferase tag:?-?|necessary binding region:1-70|binding-associated region:1..1-168..168 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:F1RGL0 uniprotkb:Q68871 intact:EBI-12519897|ensembl:ENSSSCP00000006984 intact:EBI-12522528 psi-mi:f1rgl0_pig(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1-associating protein X-1(gene name synonym) psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym) psi-mi:"MI:0096"(pull down) Johns et al. (2010) pubmed:20631090|imex:IM-26141 taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-12518981|imex:IM-26141-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSSSCG00000006552(gene)|ensembl:ENSSSCT00000007177(transcript)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1) go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128 - - - figure legend:1C-D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9823(pig-max)|taxid:9823(Max kidney cell line) - 2016/09/13 2020/01/08 rogid:6H7BAs0ch27sjTImAPCwtW5z3Gw9823 rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769 rigid:OwZTH/7Iov7pDPM3OsO/+I0T22k false glutathione s tranferase tag:?-? binding-associated region:1..1-168..168 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:F1RGL0 uniprotkb:Q68871 intact:EBI-12519897|ensembl:ENSSSCP00000006984 intact:EBI-12522528 psi-mi:f1rgl0_pig(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1-associating protein X-1(gene name synonym) psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym) psi-mi:"MI:0096"(pull down) Johns et al. (2010) pubmed:20631090|imex:IM-26141 taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-12518988|imex:IM-26141-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSSSCG00000006552(gene)|ensembl:ENSSSCT00000007177(transcript)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1) go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128 - - - figure legend:5C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9823(pig-max)|taxid:9823(Max kidney cell line) - 2016/09/13 2020/01/08 rogid:6H7BAs0ch27sjTImAPCwtW5z3Gw9823 rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769 rigid:OwZTH/7Iov7pDPM3OsO/+I0T22k false - sufficient binding region:106-143|glutathione s tranferase tag:?-?|binding-associated region:1..1-168..168 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q68871 uniprotkb:F1RGL0 intact:EBI-12522528 intact:EBI-12519897|ensembl:ENSSSCP00000006984 psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym) psi-mi:f1rgl0_pig(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1-associating protein X-1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Johns et al. (2010) pubmed:20631090|imex:IM-26141 taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-12519006|imex:IM-26141-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128 ensembl:ENSSSCG00000006552(gene)|ensembl:ENSSSCT00000007177(transcript)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1) go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9823(pig-max)|taxid:9823(Max kidney cell line) - 2016/09/13 2020/01/08 rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769 rogid:6H7BAs0ch27sjTImAPCwtW5z3Gw9823 rigid:OwZTH/7Iov7pDPM3OsO/+I0T22k false green fluorescent protein tag:?-?|binding-associated region:1..1-168..168 - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q68871 uniprotkb:F1RGL0 intact:EBI-12522528 intact:EBI-12519897|ensembl:ENSSSCP00000006984 psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym) psi-mi:f1rgl0_pig(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1-associating protein X-1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Johns et al. (2010) pubmed:20631090|imex:IM-26141 taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-12589815|imex:IM-26141-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128 ensembl:ENSSSCG00000006552(gene)|ensembl:ENSSSCT00000007177(transcript)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1) go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0005783"(endoplasmic reticulum) - - figure legend:6|comment:In figure 6 co-localization was seen in both peri-nuclear and cytoplasmic puncta;the authors suggest these puncta may be mitochondrial.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9823(pig-max)|taxid:9823(Max kidney cell line) - 2016/09/13 2020/01/08 rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769 rogid:6H7BAs0ch27sjTImAPCwtW5z3Gw9823 rigid:OwZTH/7Iov7pDPM3OsO/+I0T22k false green fluorescent protein tag:?-?|sufficient binding region:106-143|binding-associated region:1..1-168..168 - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0422"(immunostaining)