#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q6KF10-PRO_0000042253	uniprotkb:P98066	intact:EBI-11710019	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:q6kf10-pro_0000042253(display_long)|uniprotkb:GDF6(gene name)|psi-mi:GDF6(display_short)|uniprotkb:BMP13(gene name synonym)|uniprotkb:GDF16(gene name synonym)|uniprotkb:Bone morphogenetic protein 13(gene name synonym)|uniprotkb:Growth/differentiation factor 16(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11709976|imex:IM-25292-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11709984(chain-parent)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	chain-seq-start:336|chain-seq-end:455	-	figure legend:6,7,8|comment:"The Link domain (aas36-133 of pre-protein) and Cub_C (aas 129-277) region of TSG6 have a much lower level of binding as compared to full-length TSG-6."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/11	2016/06/01	rogid:1Y9GzD5Gjl1scV97dvkWeoKHiQU9606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:VwATak+vfuyRL0AEt1p+SdTGubQ	false	-	v5 tag:c-c|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P18075-PRO_0000033877	uniprotkb:P98066	intact:EBI-11710035	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:p18075-pro_0000033877(display_long)|uniprotkb:Osteogenic protein 1(gene name synonym)|uniprotkb:BMP7(gene name)|psi-mi:BMP7(display_short)|uniprotkb:OP1(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11710027|imex:IM-25292-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1035195(chain-parent)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	chain-seq-start:293|chain-seq-end:431	-	figure legend:6-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/11	2016/06/01	rogid:F7ectRt4DaLo4DGNhSrQHnhKBTk9606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:yFtnCjGVOT3uBG+9xwyIoj9hHRY	false	-	v5 tag:c-c|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P12643-PRO_0000033825	uniprotkb:P98066	intact:EBI-9697918	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:p12643-pro_0000033825(display_long)|uniprotkb:BMP2(gene name)|psi-mi:BMP2(display_short)|uniprotkb:BMP2A(gene name synonym)|uniprotkb:Bone morphogenetic protein 2A(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11710041|imex:IM-25292-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1029262(chain-parent)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	chain-seq-start:283|chain-seq-end:396	-	figure legend:6, 7,8|comment:"The Link domain  (aas36-133 of pre-protein)  and Cub_C (aas 129-277) region  of TSG6  have a much lower level of binding as  compared to full-length TSG-6."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/11	2016/06/01	rogid:2Wbw1lWxXHyuTq0kaOwvhTVgQJ09606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:gIpzyYVusuOmv1cYWz+ypjMoMBY	false	L-methionine residue:n-n	v5 tag:c-c|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P22003-PRO_0000033867	uniprotkb:P98066	intact:EBI-11710109	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:p22003-pro_0000033867(display_long)|uniprotkb:BMP5(gene name)|psi-mi:BMP5(display_short)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11710055|imex:IM-25292-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11710063(chain-parent)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	chain-seq-start:317|chain-seq-end:454	-	figure legend:6-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/11	2016/06/01	rogid:k5Ecolyt1CedpXAmgCgtKyupJr09606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:ieKakLkNgZsX8f1e5IP5s4Qqkbc	false	-	v5 tag:c-c|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P12644-PRO_0000033857	uniprotkb:P98066	intact:EBI-11710391	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:p12644-pro_0000033857(display_long)|uniprotkb:BMP4(gene name)|psi-mi:BMP4(display_short)|uniprotkb:BMP2B(gene name synonym)|uniprotkb:DVR4(gene name synonym)|uniprotkb:Bone morphogenetic protein 2B(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11710382|imex:IM-25292-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1998134(chain-parent)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	chain-seq-start:293|chain-seq-end:408	-	figure legend:6-5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/11	2016/06/01	rogid:A9qmhE6T/f7eP2EgZdkz+cj6Wf49606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:jr2mhe4q0lZPIgk4vMJikR19NDU	false	-	v5 tag:c-c|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P22004	uniprotkb:P98066	intact:EBI-11710407|uniprotkb:Q5TCP3|ensembl:ENSP00000283147	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:bmp6_human(display_long)|uniprotkb:BMP6(gene name)|psi-mi:BMP6(display_short)|uniprotkb:VGR(gene name synonym)|uniprotkb:VG-1-related protein(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11710398|imex:IM-25292-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001709.1|ensembl:ENSG00000153162(gene)|ensembl:ENST00000283147(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001822"(kidney development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0014823"(response to activity)|go:"GO:0043117"(positive regulation of vascular permeability)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030539"(male genitalia development)|go:"GO:0051216"(cartilage development)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0031982"(vesicle)|go:"GO:0060586"(multicellular organismal iron ion homeostasis)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1903392"(negative regulation of adherens junction organization)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000860"(positive regulation of aldosterone secretion)|interpro:IPR001111("Transforming growth factor beta (TGFb), N-terminal")|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR017948|go:"GO:0032026"(response to magnesium ion)|interpro:IPR029034|rcsb pdb:2QCW|rcsb pdb:2R52|rcsb pdb:2R53|rcsb pdb:6OMO|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032349"(positive regulation of aldosterone biosynthetic process)|dip:DIP-5797N	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	-	-	figure legend:6-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/11	2016/06/01	rogid:bqVFwReIU4gqfuTZnSkFMenyUuk9606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:7CIFde5PuOqFIbDwodLS5DyNnV0	false	sufficient binding region:382-513(IPR001839)	v5 tag:c-c|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P43026-PRO_0000033913	uniprotkb:P98066	intact:EBI-11710512	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:p43026-pro_0000033913(display_long)|uniprotkb:GDF5(gene name)|psi-mi:GDF5(display_short)|uniprotkb:BMP14(gene name synonym)|uniprotkb:CDMP1(gene name synonym)|uniprotkb:Bone morphogenetic protein 14(gene name synonym)|uniprotkb:Cartilage-derived morphogenetic protein 1(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 4(gene name synonym)|uniprotkb:Radotermin(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11710502|imex:IM-25292-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8571476(chain-parent)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	chain-seq-start:382|chain-seq-end:501	-	figure legend:6,7i|comment:"The Link domain (aas36-133 of pre-protein) and Cub_C (aas 129-277) region of TSG6 have a much lower level of binding as compared to full-length TSG-6."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/11	2016/06/01	rogid:yCmpDeLzsiaeDaxgGyvUS53NRRg9606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:4d7Fi8peINU+5ywWg+kF5iOkXjA	false	-	v5 tag:c-c|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:O14788	uniprotkb:P98066	intact:EBI-7404021|intact:MINT-8247611|uniprotkb:Q96Q17|uniprotkb:Q9P2Q3|uniprotkb:O14723|ensembl:ENSP00000381775	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:tnf11_human(display_long)|uniprotkb:TNFSF11(gene name)|psi-mi:TNFSF11(display_short)|uniprotkb:OPGL(gene name synonym)|uniprotkb:Osteoclast differentiation factor(gene name synonym)|uniprotkb:Osteoprotegerin ligand(gene name synonym)|uniprotkb:RANKL(gene name synonym)|uniprotkb:Receptor activator of nuclear factor kappa-B ligand(gene name synonym)|uniprotkb:TNF-related activation-induced cytokine(gene name synonym)|uniprotkb:TRANCE(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11710639|imex:IM-25292-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011533582.1|refseq:NP_143026.1|refseq:NP_003692.1|refseq:XP_016876292.1|ensembl:ENSG00000120659(gene)|ensembl:ENST00000398795(transcript)|go:"GO:0001503"(ossification)|go:"GO:0002158"(osteoclast proliferation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0036035"(osteoclast development)|go:"GO:0038001"(paracrine signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044691"(tooth eruption)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051466"(positive regulation of corticotropin-releasing hormone secretion)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0071847"(TNFSF11-mediated signaling pathway)|go:"GO:0071848"(positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1904616"(regulation of actin binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR017355(Tumour necrosis factor ligand superfamily member, 10/11)|rcsb pdb:3URF|rcsb pdb:5BNQ|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|go:"GO:0071812"(positive regulation of fever generation by positive regulation of prostaglandin secretion)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	comment:mint|comment:homomint	-	figure legend:8B|comment:No result  was obtained with CUB_C_TSG6 construct.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/11	2016/06/01	rogid:ckHu030pHQr694G3Eyrl8HmHFqM9606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:+DPvs2QXC5Vph+/kRY7u6n8YJy8	false	sufficient binding region:142-317(IPR006052)|mutation:142-142	binding-associated region:36-133	1	1	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:O14788	uniprotkb:P98066	intact:EBI-7404021|intact:MINT-8247611|uniprotkb:Q96Q17|uniprotkb:Q9P2Q3|uniprotkb:O14723|ensembl:ENSP00000381775	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:tnf11_human(display_long)|uniprotkb:TNFSF11(gene name)|psi-mi:TNFSF11(display_short)|uniprotkb:OPGL(gene name synonym)|uniprotkb:Osteoclast differentiation factor(gene name synonym)|uniprotkb:Osteoprotegerin ligand(gene name synonym)|uniprotkb:RANKL(gene name synonym)|uniprotkb:Receptor activator of nuclear factor kappa-B ligand(gene name synonym)|uniprotkb:TNF-related activation-induced cytokine(gene name synonym)|uniprotkb:TRANCE(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16357824|imex:IM-25292-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011533582.1|refseq:NP_143026.1|refseq:NP_003692.1|refseq:XP_016876292.1|ensembl:ENSG00000120659(gene)|ensembl:ENST00000398795(transcript)|go:"GO:0001503"(ossification)|go:"GO:0002158"(osteoclast proliferation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0036035"(osteoclast development)|go:"GO:0038001"(paracrine signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044691"(tooth eruption)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051466"(positive regulation of corticotropin-releasing hormone secretion)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0071847"(TNFSF11-mediated signaling pathway)|go:"GO:0071848"(positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1904616"(regulation of actin binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR017355(Tumour necrosis factor ligand superfamily member, 10/11)|rcsb pdb:3URF|rcsb pdb:5BNQ|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|go:"GO:0071812"(positive regulation of fever generation by positive regulation of prostaglandin secretion)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	comment:mint|comment:homomint	-	figure legend:8 A/B|comment:No significant  result  was obtained with CUB_C_TSG6 or Link constructs.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/11	2017/09/08	rogid:ckHu030pHQr694G3Eyrl8HmHFqM9606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:+DPvs2QXC5Vph+/kRY7u6n8YJy8	false	sufficient binding region:142-317(IPR006052)|mutation:142-142	v5 tag:c-c|his tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:O14788	uniprotkb:P98066	intact:EBI-7404021|intact:MINT-8247611|uniprotkb:Q96Q17|uniprotkb:Q9P2Q3|uniprotkb:O14723|ensembl:ENSP00000381775	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:tnf11_human(display_long)|uniprotkb:TNFSF11(gene name)|psi-mi:TNFSF11(display_short)|uniprotkb:OPGL(gene name synonym)|uniprotkb:Osteoclast differentiation factor(gene name synonym)|uniprotkb:Osteoprotegerin ligand(gene name synonym)|uniprotkb:RANKL(gene name synonym)|uniprotkb:Receptor activator of nuclear factor kappa-B ligand(gene name synonym)|uniprotkb:TNF-related activation-induced cytokine(gene name synonym)|uniprotkb:TRANCE(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16357855|imex:IM-25292-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011533582.1|refseq:NP_143026.1|refseq:NP_003692.1|refseq:XP_016876292.1|ensembl:ENSG00000120659(gene)|ensembl:ENST00000398795(transcript)|go:"GO:0001503"(ossification)|go:"GO:0002158"(osteoclast proliferation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0036035"(osteoclast development)|go:"GO:0038001"(paracrine signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044691"(tooth eruption)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051466"(positive regulation of corticotropin-releasing hormone secretion)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0071847"(TNFSF11-mediated signaling pathway)|go:"GO:0071848"(positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1904616"(regulation of actin binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR017355(Tumour necrosis factor ligand superfamily member, 10/11)|rcsb pdb:3URF|rcsb pdb:5BNQ|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|go:"GO:0071812"(positive regulation of fever generation by positive regulation of prostaglandin secretion)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	comment:mint|comment:homomint	-	figure legend:8C|comment:the extent of binding to Link_TSG6 and CUB_C_TSG6 was lower than that seen for the full-length protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/11	2017/08/14	rogid:ckHu030pHQr694G3Eyrl8HmHFqM9606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:+DPvs2QXC5Vph+/kRY7u6n8YJy8	false	sufficient binding region:142-317(IPR006052)|mutation:142-142|biotin tag:?-?	binding-associated region:129-277|binding-associated region:36-133	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q6KF10-PRO_0000042253	uniprotkb:P98066	intact:EBI-11710019	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:q6kf10-pro_0000042253(display_long)|uniprotkb:GDF6(gene name)|psi-mi:GDF6(display_short)|uniprotkb:BMP13(gene name synonym)|uniprotkb:GDF16(gene name synonym)|uniprotkb:Bone morphogenetic protein 13(gene name synonym)|uniprotkb:Growth/differentiation factor 16(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11710174|imex:IM-25292-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11709984(chain-parent)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	chain-seq-start:336|chain-seq-end:455	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.236x10^-6(molar)	2016/05/11	2016/06/01	rogid:1Y9GzD5Gjl1scV97dvkWeoKHiQU9606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:VwATak+vfuyRL0AEt1p+SdTGubQ	false	-	v5 tag:c-c|his tag:c-c	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12643-PRO_0000033825	uniprotkb:P98066	intact:EBI-9697918	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:p12643-pro_0000033825(display_long)|uniprotkb:BMP2(gene name)|psi-mi:BMP2(display_short)|uniprotkb:BMP2A(gene name synonym)|uniprotkb:Bone morphogenetic protein 2A(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11710183|imex:IM-25292-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1029262(chain-parent)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	chain-seq-start:283|chain-seq-end:396	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.22x10^-6(molar)	2016/05/11	2016/06/01	rogid:2Wbw1lWxXHyuTq0kaOwvhTVgQJ09606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:gIpzyYVusuOmv1cYWz+ypjMoMBY	false	L-methionine residue:n-n	v5 tag:c-c|his tag:c-c	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14788	uniprotkb:P98066	intact:EBI-7404021|intact:MINT-8247611|uniprotkb:Q96Q17|uniprotkb:Q9P2Q3|uniprotkb:O14723|ensembl:ENSP00000381775	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:tnf11_human(display_long)|uniprotkb:TNFSF11(gene name)|psi-mi:TNFSF11(display_short)|uniprotkb:OPGL(gene name synonym)|uniprotkb:Osteoclast differentiation factor(gene name synonym)|uniprotkb:Osteoprotegerin ligand(gene name synonym)|uniprotkb:RANKL(gene name synonym)|uniprotkb:Receptor activator of nuclear factor kappa-B ligand(gene name synonym)|uniprotkb:TNF-related activation-induced cytokine(gene name synonym)|uniprotkb:TRANCE(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11710530|imex:IM-25292-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011533582.1|refseq:NP_143026.1|refseq:NP_003692.1|refseq:XP_016876292.1|ensembl:ENSG00000120659(gene)|ensembl:ENST00000398795(transcript)|go:"GO:0001503"(ossification)|go:"GO:0002158"(osteoclast proliferation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0036035"(osteoclast development)|go:"GO:0038001"(paracrine signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044691"(tooth eruption)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051466"(positive regulation of corticotropin-releasing hormone secretion)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0071847"(TNFSF11-mediated signaling pathway)|go:"GO:0071848"(positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1904616"(regulation of actin binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR017355(Tumour necrosis factor ligand superfamily member, 10/11)|rcsb pdb:3URF|rcsb pdb:5BNQ|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|go:"GO:0071812"(positive regulation of fever generation by positive regulation of prostaglandin secretion)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	comment:mint|comment:homomint	-	figure legend:Table 2|comment:No result  was obtained with CUB_C_TSG6 construct.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.97x10^-6(molar)	2016/05/11	2016/06/01	rogid:ckHu030pHQr694G3Eyrl8HmHFqM9606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:+DPvs2QXC5Vph+/kRY7u6n8YJy8	false	sufficient binding region:142-317(IPR006052)|mutation:142-142	v5 tag:c-c|his tag:c-c	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12643-PRO_0000033825	uniprotkb:P98066	intact:EBI-9697918	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:p12643-pro_0000033825(display_long)|uniprotkb:BMP2(gene name)|psi-mi:BMP2(display_short)|uniprotkb:BMP2A(gene name synonym)|uniprotkb:Bone morphogenetic protein 2A(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11710589|imex:IM-25292-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1029262(chain-parent)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	chain-seq-start:283|chain-seq-end:396	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/11	2016/06/01	rogid:2Wbw1lWxXHyuTq0kaOwvhTVgQJ09606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:gIpzyYVusuOmv1cYWz+ypjMoMBY	false	L-methionine residue:n-n	binding-associated region:36-133(IPR000538)|binding-associated region:129-277	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6KF10-PRO_0000042253	uniprotkb:P98066	intact:EBI-11710019	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:q6kf10-pro_0000042253(display_long)|uniprotkb:GDF6(gene name)|psi-mi:GDF6(display_short)|uniprotkb:BMP13(gene name synonym)|uniprotkb:GDF16(gene name synonym)|uniprotkb:Bone morphogenetic protein 13(gene name synonym)|uniprotkb:Growth/differentiation factor 16(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11710608|imex:IM-25292-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11709984(chain-parent)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	chain-seq-start:336|chain-seq-end:455	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/11	2016/06/01	rogid:1Y9GzD5Gjl1scV97dvkWeoKHiQU9606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:VwATak+vfuyRL0AEt1p+SdTGubQ	false	-	binding-associated region:36-133(IPR000538)|binding-associated region:129-277	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43026-PRO_0000033913	uniprotkb:P98066	intact:EBI-11710512	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:p43026-pro_0000033913(display_long)|uniprotkb:GDF5(gene name)|psi-mi:GDF5(display_short)|uniprotkb:BMP14(gene name synonym)|uniprotkb:CDMP1(gene name synonym)|uniprotkb:Bone morphogenetic protein 14(gene name synonym)|uniprotkb:Cartilage-derived morphogenetic protein 1(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 4(gene name synonym)|uniprotkb:Radotermin(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16357875|imex:IM-25292-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8571476(chain-parent)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	chain-seq-start:382|chain-seq-end:501	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.18x10^-6(molar)	2016/05/11	2017/08/14	rogid:yCmpDeLzsiaeDaxgGyvUS53NRRg9606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:4d7Fi8peINU+5ywWg+kF5iOkXjA	false	-	v5 tag:c-c|his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43026-PRO_0000033913	uniprotkb:P98066	intact:EBI-11710512	intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347	psi-mi:p43026-pro_0000033913(display_long)|uniprotkb:GDF5(gene name)|psi-mi:GDF5(display_short)|uniprotkb:BMP14(gene name synonym)|uniprotkb:CDMP1(gene name synonym)|uniprotkb:Bone morphogenetic protein 14(gene name synonym)|uniprotkb:Cartilage-derived morphogenetic protein 1(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 4(gene name synonym)|uniprotkb:Radotermin(gene name synonym)	psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Mahoney et al. (2008)	imex:IM-25292|pubmed:18586671	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16357886|imex:IM-25292-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8571476(chain-parent)	refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695	-	chain-seq-start:382|chain-seq-end:501	-	figure legend:Table 2i|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/11	2017/08/14	rogid:yCmpDeLzsiaeDaxgGyvUS53NRRg9606	rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606	rigid:4d7Fi8peINU+5ywWg+kF5iOkXjA	false	-	binding-associated region:36-133|binding-associated region:129-277	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)