#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q62187 uniprotkb:Q9UIF9 intact:EBI-11705418|uniprotkb:Q9JKK5|ensembl:ENSMUSP00000097809 intact:EBI-934890|uniprotkb:O00536|uniprotkb:O15030|uniprotkb:Q96H26|uniprotkb:B3KN66|uniprotkb:Q68DI8|ensembl:ENSP00000446880 psi-mi:ttf1_mouse(display_long)|uniprotkb:Ttf1(gene name)|psi-mi:Ttf1(display_short)|uniprotkb:RNA polymerase I termination factor(gene name synonym)|uniprotkb:Transcription termination factor I(gene name synonym) psi-mi:baz2a_human(display_long)|uniprotkb:BAZ2A(gene name)|psi-mi:BAZ2A(display_short)|uniprotkb:KIAA0314(gene name synonym)|uniprotkb:TIP5(gene name synonym)|uniprotkb:Transcription termination factor I-interacting protein 5(gene name synonym)|uniprotkb:hWALp3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Strohner et al. (2001) imex:IM-25315|pubmed:11532953 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11705450|imex:IM-25315-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033468.2|refseq:XP_006497915.1|ensembl:ENSMUSG00000026803(gene)|ensembl:ENSMUST00000100237(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0008156"(negative regulation of DNA replication)|interpro:IPR001005(SANT, DNA-binding)|reactome:R-MMU-5683826|reactome:R-MMU-73762|reactome:R-MMU-73863 refseq:NP_038477.2|ensembl:ENSG00000076108(gene)|ensembl:ENST00000551812(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017956|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028940|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF9|rcsb pdb:4LZ2|rcsb pdb:4Q6F|rcsb pdb:4QBM|rcsb pdb:4QF2|rcsb pdb:5AGQ|rcsb pdb:5MGJ|rcsb pdb:5MGK|rcsb pdb:5MGL|rcsb pdb:5MGM|rcsb pdb:5OR8|rcsb pdb:5T8R|rcsb pdb:6FAP|rcsb pdb:6FG6|rcsb pdb:6FGF|rcsb pdb:6FGG|rcsb pdb:6FGH|rcsb pdb:6FGI|rcsb pdb:6FGL|rcsb pdb:6FGV|rcsb pdb:6FGW|rcsb pdb:6FHU|rcsb pdb:6FI0|rcsb pdb:6FKP|reactome:R-HSA-427413 go:"GO:0005730"(nucleolus) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/05/20 2016/05/23 rogid:hXmFu51e7lwHfu7WzAHHIAz+doA10090 rogid:KfCpUyqOdz/VMjAKhvKyV9Ft1vs9606 rigid:3ViH0/PpR9D2s3paeGCb3qmG2qw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UIF9 uniprotkb:Q62187 intact:EBI-934890|uniprotkb:O00536|uniprotkb:O15030|uniprotkb:Q96H26|uniprotkb:B3KN66|uniprotkb:Q68DI8|ensembl:ENSP00000446880 intact:EBI-11705418|uniprotkb:Q9JKK5|ensembl:ENSMUSP00000097809 psi-mi:baz2a_human(display_long)|uniprotkb:BAZ2A(gene name)|psi-mi:BAZ2A(display_short)|uniprotkb:KIAA0314(gene name synonym)|uniprotkb:TIP5(gene name synonym)|uniprotkb:Transcription termination factor I-interacting protein 5(gene name synonym)|uniprotkb:hWALp3(gene name synonym) psi-mi:ttf1_mouse(display_long)|uniprotkb:Ttf1(gene name)|psi-mi:Ttf1(display_short)|uniprotkb:RNA polymerase I termination factor(gene name synonym)|uniprotkb:Transcription termination factor I(gene name synonym) psi-mi:"MI:0096"(pull down) Strohner et al. (2001) imex:IM-25315|pubmed:11532953 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11705551|imex:IM-25315-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038477.2|ensembl:ENSG00000076108(gene)|ensembl:ENST00000551812(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017956|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028940|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF9|rcsb pdb:4LZ2|rcsb pdb:4Q6F|rcsb pdb:4QBM|rcsb pdb:4QF2|rcsb pdb:5AGQ|rcsb pdb:5MGJ|rcsb pdb:5MGK|rcsb pdb:5MGL|rcsb pdb:5MGM|rcsb pdb:5OR8|rcsb pdb:5T8R|rcsb pdb:6FAP|rcsb pdb:6FG6|rcsb pdb:6FGF|rcsb pdb:6FGG|rcsb pdb:6FGH|rcsb pdb:6FGI|rcsb pdb:6FGL|rcsb pdb:6FGV|rcsb pdb:6FGW|rcsb pdb:6FHU|rcsb pdb:6FI0|rcsb pdb:6FKP|reactome:R-HSA-427413 refseq:NP_033468.2|refseq:XP_006497915.1|ensembl:ENSMUSG00000026803(gene)|ensembl:ENSMUST00000100237(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0008156"(negative regulation of DNA replication)|interpro:IPR001005(SANT, DNA-binding)|reactome:R-MMU-5683826|reactome:R-MMU-73762|reactome:R-MMU-73863 - - - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/20 2016/05/23 rogid:KfCpUyqOdz/VMjAKhvKyV9Ft1vs9606 rogid:hXmFu51e7lwHfu7WzAHHIAz+doA10090 rigid:3ViH0/PpR9D2s3paeGCb3qmG2qw false necessary binding region:332-726|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UIF9 uniprotkb:Q62187 intact:EBI-934890|uniprotkb:O00536|uniprotkb:O15030|uniprotkb:Q96H26|uniprotkb:B3KN66|uniprotkb:Q68DI8|ensembl:ENSP00000446880 intact:EBI-11705418|uniprotkb:Q9JKK5|ensembl:ENSMUSP00000097809 psi-mi:baz2a_human(display_long)|uniprotkb:BAZ2A(gene name)|psi-mi:BAZ2A(display_short)|uniprotkb:KIAA0314(gene name synonym)|uniprotkb:TIP5(gene name synonym)|uniprotkb:Transcription termination factor I-interacting protein 5(gene name synonym)|uniprotkb:hWALp3(gene name synonym) psi-mi:ttf1_mouse(display_long)|uniprotkb:Ttf1(gene name)|psi-mi:Ttf1(display_short)|uniprotkb:RNA polymerase I termination factor(gene name synonym)|uniprotkb:Transcription termination factor I(gene name synonym) psi-mi:"MI:0096"(pull down) Strohner et al. (2001) imex:IM-25315|pubmed:11532953 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11705564|imex:IM-25315-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038477.2|ensembl:ENSG00000076108(gene)|ensembl:ENST00000551812(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017956|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028940|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF9|rcsb pdb:4LZ2|rcsb pdb:4Q6F|rcsb pdb:4QBM|rcsb pdb:4QF2|rcsb pdb:5AGQ|rcsb pdb:5MGJ|rcsb pdb:5MGK|rcsb pdb:5MGL|rcsb pdb:5MGM|rcsb pdb:5OR8|rcsb pdb:5T8R|rcsb pdb:6FAP|rcsb pdb:6FG6|rcsb pdb:6FGF|rcsb pdb:6FGG|rcsb pdb:6FGH|rcsb pdb:6FGI|rcsb pdb:6FGL|rcsb pdb:6FGV|rcsb pdb:6FGW|rcsb pdb:6FHU|rcsb pdb:6FI0|rcsb pdb:6FKP|reactome:R-HSA-427413 refseq:NP_033468.2|refseq:XP_006497915.1|ensembl:ENSMUSG00000026803(gene)|ensembl:ENSMUST00000100237(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0008156"(negative regulation of DNA replication)|interpro:IPR001005(SANT, DNA-binding)|reactome:R-MMU-5683826|reactome:R-MMU-73762|reactome:R-MMU-73863 - - - figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/20 2016/05/23 rogid:KfCpUyqOdz/VMjAKhvKyV9Ft1vs9606 rogid:hXmFu51e7lwHfu7WzAHHIAz+doA10090 rigid:3ViH0/PpR9D2s3paeGCb3qmG2qw false necessary binding region:332-726 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9Z2E1 intact:EBI-11705942 intact:EBI-5716946|uniprotkb:E9QMV9|uniprotkb:Q811D9|uniprotkb:Q9Z2D9|ensembl:ENSMUSP00000073701 - psi-mi:mbd2_mouse(display_long)|uniprotkb:Mbd2(gene name)|psi-mi:Mbd2(display_short)|uniprotkb:Methyl-CpG-binding protein MBD2(gene name synonym) psi-mi:gam12(display_short)|psi-mi:EBI-11705942(display_long) psi-mi:"MI:0892"(solid phase assay) Strohner et al. (2001) imex:IM-25315|pubmed:11532953 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:32630(synthetic construct)|taxid:32630(synthetic construct) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11705880|imex:IM-25315-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0318"(nucleic acid) refseq:NP_034903.2|refseq:NP_001298000.1|ensembl:ENSMUSG00000024513(gene)|ensembl:ENSMUST00000074058(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042711"(maternal behavior)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0048568"(embryonic organ development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025884|interpro:IPR032343|mint:Q9Z2E1|reactome:R-MMU-427413|reactome:R-MMU-73728 pubmed:9774669(see-also)|pubmed:9774669(see-also) - - comment:"MBD2 only binds the methylated oligonucleotide (all the C are methylated except for the first one and the last one)" figure legend:Fig. 4B|comment:"MBD2 only binds the oligonucleotide when it is methylated (GAM12)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/20 2016/05/24 rogid:WxzH0gNkMXwFmBK/RWr2/RqWjXM10090 - - false - 32p radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-11706198 uniprotkb:Q9UIF9 - intact:EBI-934890|uniprotkb:O00536|uniprotkb:O15030|uniprotkb:Q96H26|uniprotkb:B3KN66|uniprotkb:Q68DI8|ensembl:ENSP00000446880 psi-mi:gac(display_short)|psi-mi:EBI-11706198(display_long) psi-mi:baz2a_human(display_long)|uniprotkb:BAZ2A(gene name)|psi-mi:BAZ2A(display_short)|uniprotkb:KIAA0314(gene name synonym)|uniprotkb:TIP5(gene name synonym)|uniprotkb:Transcription termination factor I-interacting protein 5(gene name synonym)|uniprotkb:hWALp3(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Strohner et al. (2001) imex:IM-25315|pubmed:11532953 taxid:32630(synthetic construct)|taxid:32630(synthetic construct) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11706196|imex:IM-25315-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) pubmed:9774669(see-also) refseq:NP_038477.2|ensembl:ENSG00000076108(gene)|ensembl:ENST00000551812(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017956|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028940|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF9|rcsb pdb:4LZ2|rcsb pdb:4Q6F|rcsb pdb:4QBM|rcsb pdb:4QF2|rcsb pdb:5AGQ|rcsb pdb:5MGJ|rcsb pdb:5MGK|rcsb pdb:5MGL|rcsb pdb:5MGM|rcsb pdb:5OR8|rcsb pdb:5T8R|rcsb pdb:6FAP|rcsb pdb:6FG6|rcsb pdb:6FGF|rcsb pdb:6FGG|rcsb pdb:6FGH|rcsb pdb:6FGI|rcsb pdb:6FGL|rcsb pdb:6FGV|rcsb pdb:6FGW|rcsb pdb:6FHU|rcsb pdb:6FI0|rcsb pdb:6FKP|reactome:R-HSA-427413 - - - figure legend:Fig.4B|comment:DNA methylation doesn't alter the DNA binding properties of TIP5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/20 2016/05/24 - rogid:KfCpUyqOdz/VMjAKhvKyV9Ft1vs9606 - false 32p radiolabel:?-? sufficient binding region:510-611|his tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9UIF9 intact:EBI-11706784 intact:EBI-934890|uniprotkb:O00536|uniprotkb:O15030|uniprotkb:Q96H26|uniprotkb:B3KN66|uniprotkb:Q68DI8|ensembl:ENSP00000446880 - psi-mi:baz2a_human(display_long)|uniprotkb:BAZ2A(gene name)|psi-mi:BAZ2A(display_short)|uniprotkb:KIAA0314(gene name synonym)|uniprotkb:TIP5(gene name synonym)|uniprotkb:Transcription termination factor I-interacting protein 5(gene name synonym)|uniprotkb:hWALp3(gene name synonym) psi-mi:oligonucleotide(display_short)|psi-mi:EBI-11706784(display_long) psi-mi:"MI:0892"(solid phase assay) Strohner et al. (2001) imex:IM-25315|pubmed:11532953 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:32630(synthetic construct)|taxid:32630(synthetic construct) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11706792|imex:IM-25315-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0318"(nucleic acid) refseq:NP_038477.2|ensembl:ENSG00000076108(gene)|ensembl:ENST00000551812(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017956|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028940|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF9|rcsb pdb:4LZ2|rcsb pdb:4Q6F|rcsb pdb:4QBM|rcsb pdb:4QF2|rcsb pdb:5AGQ|rcsb pdb:5MGJ|rcsb pdb:5MGK|rcsb pdb:5MGL|rcsb pdb:5MGM|rcsb pdb:5OR8|rcsb pdb:5T8R|rcsb pdb:6FAP|rcsb pdb:6FG6|rcsb pdb:6FGF|rcsb pdb:6FGG|rcsb pdb:6FGH|rcsb pdb:6FGI|rcsb pdb:6FGL|rcsb pdb:6FGV|rcsb pdb:6FGW|rcsb pdb:6FHU|rcsb pdb:6FI0|rcsb pdb:6FKP|reactome:R-HSA-427413 pubmed:11532953(see-also) - - comment:It harbors the upstream control element of the murine rDNA promoter figure legend:Fig. 4C|comment:"If TAM domain was fused to two AT-hooks (510aa-723aa) the DNA binding efficiency increased by almost two orders of magnitude."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/20 2016/05/25 rogid:KfCpUyqOdz/VMjAKhvKyV9Ft1vs9606 - - false sufficient binding region:510-611|his tag:?-? 32p radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q91ZW3 uniprotkb:Q91YE5 intact:EBI-927547|uniprotkb:Q8C791|uniprotkb:Q8CA22|uniprotkb:Q8VDG1|uniprotkb:Q925M9|ensembl:ENSMUSP00000044361 intact:EBI-11705475|uniprotkb:Q3U235|uniprotkb:Q80U42 psi-mi:smca5_mouse(display_long)|uniprotkb:Smarca5(gene name)|psi-mi:Smarca5(display_short)|uniprotkb:Snf2h(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:baz2a_mouse(display_long)|uniprotkb:Baz2a(gene name)|psi-mi:Baz2a(display_short)|uniprotkb:Kiaa0314(gene name synonym)|uniprotkb:Tip5(gene name synonym)|uniprotkb:Transcription termination factor I-interacting protein 5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Strohner et al. (2001) imex:IM-25315|pubmed:11532953 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11706831|imex:IM-25315-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_444354.2|dip:DIP-36073N|ensembl:ENSMUSG00000031715(gene)|ensembl:ENSMUST00000043359(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031010"(ISWI-type complex)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:Q91ZW3|reactome:R-MMU-5250924|reactome:R-MMU-5693565|reactome:R-MMU-606279 interpro:IPR017956|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR018501|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR028940|interpro:IPR028942|interpro:IPR028941|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR019787|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034770"(histone H4-K20 methylation)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0006338"(chromatin remodeling)|interpro:IPR036427|interpro:IPR037374 - - - figure legend:Fig.5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2016/05/20 2016/05/25 rogid:+HXPfdDGqKssFXooxGP7gM+u8Oc10090 rogid:aZTBEOQMUwyd4QK1SxxjTciF/9M10090 rigid:VGeSUIRYa+Mdc6UixXG5IicwFT8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)