#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P48039	uniprotkb:Q60770	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-8430169|uniprotkb:Q3U2S2|uniprotkb:Q3TE73|uniprotkb:Q3U8D9|uniprotkb:Q3UUB0|intact:MINT-4136068|uniprotkb:Q3UA91|intact:UNK-5404274|ensembl:ENSMUSP00000099681	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:stxb3_mouse(display_long)|uniprotkb:Stxbp3(gene name)|psi-mi:Stxbp3(display_short)|uniprotkb:Stxbp3a(gene name synonym)|uniprotkb:Unc18c(gene name synonym)|uniprotkb:Protein unc-18 homolog 3(gene name synonym)|uniprotkb:Protein unc-18 homolog C(gene name synonym)|uniprotkb:Mammalian homolog of Unc-18c(gene name synonym)|uniprotkb:MUNC-18-3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11566110|imex:IM-24624-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_035634.1|dip:DIP-60305N|ensembl:ENSMUSG00000027882(gene)|ensembl:ENSMUST00000102621(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007420"(brain development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030073"(insulin secretion)|go:"GO:0030141"(secretory granule)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0032868"(response to insulin)|go:"GO:0042581"(specific granule)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070820"(tertiary granule)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098793"(presynapse)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|mint:Q60770|rcsb pdb:3PUK|reactome:R-MMU-114516	-	-	comment:mint	figure legend:2A, 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2016/02/10	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:oaYdMOhLTEvPV/ZBlzK7Uj1rxk810090	rigid:+JBK427bTgbq0wj1CFQyBkCt+wI	false	his tag:c-c|sufficient binding region:296-315	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:O55017	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-770881|uniprotkb:Q60609|ensembl:ENSMUSP00000037416	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:cac1b_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 5(gene name synonym)|uniprotkb:Brain calcium channel III(gene name synonym)|uniprotkb:Cacna1b(gene name)|psi-mi:Cacna1b(display_short)|uniprotkb:Cach5(gene name synonym)|uniprotkb:Cacnl1a5(gene name synonym)|uniprotkb:Cchn1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11566110|imex:IM-24624-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001035993.1|ensembl:ENSMUSG00000004113(gene)|ensembl:ENSMUST00000041342(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043679"(axon terminus)|go:"GO:0048265"(response to pain)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005447(Voltage-dependent calcium channel, N-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR043203|mint:O55017|reactome:R-MMU-112308	-	-	-	figure legend:2A, 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2016/02/10	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:yTkuOwWJbxQkfOPg/TA8cPvpH+Q10090	rigid:+JBK427bTgbq0wj1CFQyBkCt+wI	false	his tag:c-c|sufficient binding region:296-315	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:Q64332-2	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-775682|ensembl:ENSMUSP00000133121|ensembl:ENSMUSP00000144921	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:q64332-2(display_long)|uniprotkb:Syn2(gene name)|psi-mi:Syn2(display_short)|uniprotkb:Synapsin II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11566110|imex:IM-24624-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	intact:EBI-775668(syn2_mouse)|ensembl:ENSMUSG00000009394(gene)|ensembl:ENSMUST00000169345(transcript)|ensembl:ENSMUST00000203450(transcript)	-	-	-	figure legend:2A, 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2016/02/10	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:rzQAitKID3S24crR+QnwAgo1ynI10090	rigid:+JBK427bTgbq0wj1CFQyBkCt+wI	false	his tag:c-c|sufficient binding region:296-315	N-phosphorylated residue:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:Q64332-1	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11566113|ensembl:ENSMUSP00000009538	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:q64332-1(display_long)|uniprotkb:Synapsin II(gene name synonym)|uniprotkb:Syn2(gene name)|psi-mi:Syn2(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11566110|imex:IM-24624-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	intact:EBI-775668(isoform-parent)|ensembl:ENSMUSG00000009394(gene)|ensembl:ENSMUST00000009538(transcript)	-	-	-	figure legend:2A, 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2016/02/10	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:Y/RYUSlblGo1/3HGeKJmfS5yX+M10090	rigid:+JBK427bTgbq0wj1CFQyBkCt+wI	false	his tag:c-c|sufficient binding region:296-315	N-phosphorylated residue:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:P60879	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11566110|imex:IM-24624-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N	-	-	-	figure legend:2A, 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2016/02/10	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090	rigid:+JBK427bTgbq0wj1CFQyBkCt+wI	false	his tag:c-c|sufficient binding region:296-315	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:O88935	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-775644|uniprotkb:Q62279|uniprotkb:Q8QZT8|ensembl:ENSMUSP00000080568	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:syn1_mouse(display_long)|uniprotkb:Synapsin I(gene name synonym)|uniprotkb:Syn1(gene name)|psi-mi:Syn1(display_short)|uniprotkb:Syn-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11566110|imex:IM-24624-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001104250.1|refseq:NP_038708.3|ensembl:ENSMUSG00000037217(gene)|ensembl:ENSMUST00000081893(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045202"(synapse)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060203"(clathrin-sculpted glutamate transport vesicle membrane)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099504"(synaptic vesicle cycle)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028713|mint:O88935|reactome:R-MMU-181429|reactome:R-MMU-212676	-	-	-	figure legend:2A, 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2016/02/10	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:z48y84jWlS6gOiBDyvxI+aRYzdY10090	rigid:+JBK427bTgbq0wj1CFQyBkCt+wI	false	his tag:c-c|sufficient binding region:296-315	N-phosphorylated residue:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q60770	uniprotkb:P49286	intact:EBI-8430169|uniprotkb:Q3U2S2|uniprotkb:Q3TE73|uniprotkb:Q3U8D9|uniprotkb:Q3UUB0|intact:MINT-4136068|uniprotkb:Q3UA91|intact:UNK-5404274|ensembl:ENSMUSP00000099681	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:stxb3_mouse(display_long)|uniprotkb:Stxbp3(gene name)|psi-mi:Stxbp3(display_short)|uniprotkb:Stxbp3a(gene name synonym)|uniprotkb:Unc18c(gene name synonym)|uniprotkb:Protein unc-18 homolog 3(gene name synonym)|uniprotkb:Protein unc-18 homolog C(gene name synonym)|uniprotkb:Mammalian homolog of Unc-18c(gene name synonym)|uniprotkb:MUNC-18-3(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11572228|imex:IM-24624-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035634.1|dip:DIP-60305N|ensembl:ENSMUSG00000027882(gene)|ensembl:ENSMUST00000102621(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007420"(brain development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030073"(insulin secretion)|go:"GO:0030141"(secretory granule)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0032868"(response to insulin)|go:"GO:0042581"(specific granule)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070820"(tertiary granule)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098793"(presynapse)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|mint:Q60770|rcsb pdb:3PUK|reactome:R-MMU-114516	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	comment:mint	-	figure legend:2A, 2Btonta|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2016/02/10	rogid:oaYdMOhLTEvPV/ZBlzK7Uj1rxk810090	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rigid:GHM+M+5bhzwPo9LB5SPIAoZ+7dU	false	-	his tag:c-c|sufficient binding region:305-362	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:Q60770	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-8430169|uniprotkb:Q3U2S2|uniprotkb:Q3TE73|uniprotkb:Q3U8D9|uniprotkb:Q3UUB0|intact:MINT-4136068|uniprotkb:Q3UA91|intact:UNK-5404274|ensembl:ENSMUSP00000099681	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:stxb3_mouse(display_long)|uniprotkb:Stxbp3(gene name)|psi-mi:Stxbp3(display_short)|uniprotkb:Stxbp3a(gene name synonym)|uniprotkb:Unc18c(gene name synonym)|uniprotkb:Protein unc-18 homolog 3(gene name synonym)|uniprotkb:Protein unc-18 homolog C(gene name synonym)|uniprotkb:Mammalian homolog of Unc-18c(gene name synonym)|uniprotkb:MUNC-18-3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11572241|imex:IM-24624-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_035634.1|dip:DIP-60305N|ensembl:ENSMUSG00000027882(gene)|ensembl:ENSMUST00000102621(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007420"(brain development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030073"(insulin secretion)|go:"GO:0030141"(secretory granule)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0032868"(response to insulin)|go:"GO:0042581"(specific granule)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070820"(tertiary granule)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098793"(presynapse)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|mint:Q60770|rcsb pdb:3PUK|reactome:R-MMU-114516	-	-	comment:mint	figure legend:2A, 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2016/02/10	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:oaYdMOhLTEvPV/ZBlzK7Uj1rxk810090	rigid:YgNXV9tHCGXqbiyusC0tdiYFwqA	false	his tag:c-c|sufficient binding region:307-350	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:O88935	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-775644|uniprotkb:Q62279|uniprotkb:Q8QZT8|ensembl:ENSMUSP00000080568	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:syn1_mouse(display_long)|uniprotkb:Synapsin I(gene name synonym)|uniprotkb:Syn1(gene name)|psi-mi:Syn1(display_short)|uniprotkb:Syn-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11572241|imex:IM-24624-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001104250.1|refseq:NP_038708.3|ensembl:ENSMUSG00000037217(gene)|ensembl:ENSMUST00000081893(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045202"(synapse)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060203"(clathrin-sculpted glutamate transport vesicle membrane)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099504"(synaptic vesicle cycle)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028713|mint:O88935|reactome:R-MMU-181429|reactome:R-MMU-212676	-	-	-	figure legend:2A, 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2016/02/10	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:z48y84jWlS6gOiBDyvxI+aRYzdY10090	rigid:YgNXV9tHCGXqbiyusC0tdiYFwqA	false	his tag:c-c|sufficient binding region:307-350	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q00975	uniprotkb:P48039	intact:EBI-1055161|uniprotkb:B1AQK5|ensembl:ENSP00000360423	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:cac1b_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 5(gene name synonym)|uniprotkb:Brain calcium channel III(gene name synonym)|uniprotkb:CACNA1B(gene name)|psi-mi:CACNA1B(display_short)|uniprotkb:CACH5(gene name synonym)|uniprotkb:CACNL1A5(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11572258|imex:IM-24624-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000709.1|refseq:NP_001230741.1|ensembl:ENSG00000148408(gene)|ensembl:ENST00000371372(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045202"(synapse)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005447(Voltage-dependent calcium channel, N-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR043203|rcsb pdb:2LCM|reactome:R-HSA-112308	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/09/22	2016/02/10	rogid:R7OVT/57HywIdiczIgCa+cjqifA9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rigid:d3kNAqc9LwcGsYb3FqHTygpS+yg	false	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P60879	uniprotkb:P49286	intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11572298|imex:IM-24624-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2015/09/22	2016/02/10	rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rigid:a0Xh4yfsQK5AkK39m+IL5mTaP+k	false	ha tag:c-c	myc tag:n-n	-	-	psi-mi:"MI:1199"(anti-tag immunohistochemistry)	psi-mi:"MI:1199"(anti-tag immunohistochemistry)
uniprotkb:P60879	uniprotkb:P48039	intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11572308|imex:IM-24624-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	go:"GO:0044309"(neuron spine)	-	-	figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2015/09/22	2016/02/10	rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rigid:XfEMFcpgNLzM0CldmqBZ6zUKdmA	false	ha tag:c-c	myc tag:n-n	-	-	psi-mi:"MI:1199"(anti-tag immunohistochemistry)	psi-mi:"MI:1199"(anti-tag immunohistochemistry)
uniprotkb:Q60770	uniprotkb:P48039	intact:EBI-8430169|uniprotkb:Q3U2S2|uniprotkb:Q3TE73|uniprotkb:Q3U8D9|uniprotkb:Q3UUB0|intact:MINT-4136068|uniprotkb:Q3UA91|intact:UNK-5404274|ensembl:ENSMUSP00000099681	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:stxb3_mouse(display_long)|uniprotkb:Stxbp3(gene name)|psi-mi:Stxbp3(display_short)|uniprotkb:Stxbp3a(gene name synonym)|uniprotkb:Unc18c(gene name synonym)|uniprotkb:Protein unc-18 homolog 3(gene name synonym)|uniprotkb:Protein unc-18 homolog C(gene name synonym)|uniprotkb:Mammalian homolog of Unc-18c(gene name synonym)|uniprotkb:MUNC-18-3(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11572317|imex:IM-24624-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035634.1|dip:DIP-60305N|ensembl:ENSMUSG00000027882(gene)|ensembl:ENSMUST00000102621(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007420"(brain development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030073"(insulin secretion)|go:"GO:0030141"(secretory granule)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0032868"(response to insulin)|go:"GO:0042581"(specific granule)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070820"(tertiary granule)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098793"(presynapse)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|mint:Q60770|rcsb pdb:3PUK|reactome:R-MMU-114516	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	go:"GO:0043679"(axon terminus)	comment:mint	-	figure legend:4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2015/09/22	2016/02/10	rogid:oaYdMOhLTEvPV/ZBlzK7Uj1rxk810090	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rigid:gMv35cQ0H4foGR88x94uCjCmh+0	false	myc tag:n-n|flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:1199"(anti-tag immunohistochemistry)	psi-mi:"MI:1199"(anti-tag immunohistochemistry)
uniprotkb:P48039	uniprotkb:O75381	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-594898|uniprotkb:Q8WX51|uniprotkb:B2R7N1|uniprotkb:B3KML6|uniprotkb:B7Z1N2|intact:EBI-28983483|ensembl:ENSP00000349016	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:pex14_human(display_long)|uniprotkb:Peroxisomal membrane anchor protein PEX14(gene name synonym)|uniprotkb:PTS1 receptor-docking protein(gene name synonym)|uniprotkb:PEX14(gene name)|psi-mi:PEX14(display_short)|uniprotkb:Peroxin-14(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575798|imex:IM-24624-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_004556.1|refseq:XP_011539882.1|ensembl:ENSP00000349016|ensembl:ENSG00000142655(gene)|ensembl:ENST00000356607(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0016561"(protein import into peroxisome matrix, translocation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036250"(peroxisome transport along microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044721"(protein import into peroxisome matrix, substrate release)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|mint:O75381|rcsb pdb:2W84|rcsb pdb:2W85|rcsb pdb:4BXU|reactome:R-HSA-8866654|reactome:R-HSA-9033241|reactome:R-HSA-9603798	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:9RXZ+bR4fRStCHsMQihNHBhqmCo9606	intact-crc:245FB07BD396AF36|rigid:IR7Py0aX7NPUc4SWsdFxPuZAMLg	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q12841	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2349801|uniprotkb:Q549Z0|uniprotkb:A8K523|uniprotkb:B4DTT5|uniprotkb:D3DN90|ensembl:ENSP00000295633	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:fstl1_human(display_long)|uniprotkb:FSTL1(gene name)|psi-mi:FSTL1(display_short)|uniprotkb:FRP(gene name synonym)|uniprotkb:Follistatin-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575807|imex:IM-24624-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_009016.1|ensembl:ENSG00000163430(gene)|ensembl:ENST00000295633(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0008201"(heparin binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR011992(EF-Hand type)|interpro:IPR015369(Follistatin)|interpro:IPR036058|reactome:R-HSA-201451|reactome:R-HSA-381426|reactome:R-HSA-8957275	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:2Y10WyTpml76Ksjw+X7dXUozFg09606	intact-crc:AD20671BC52924DC|rigid:gpxQA0qjFv3H92Cnv3R78otfn2E	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11169	uniprotkb:P48039	intact:EBI-725116|uniprotkb:Q6I9U2|uniprotkb:Q9UG15|uniprotkb:D3DUU6|uniprotkb:B2R606|ensembl:ENSP00000075120	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:gtr3_human(display_long)|uniprotkb:Glucose transporter type 3, brain(gene name synonym)|uniprotkb:SLC2A3(gene name)|psi-mi:SLC2A3(display_short)|uniprotkb:GLUT3(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575816|imex:IM-24624-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008862.1|ensembl:ENSG00000059804(gene)|ensembl:ENST00000075120(transcript)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005536"(glucose binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019852"(L-ascorbic acid metabolic process)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043204"(perikaryon)|interpro:IPR020846|interpro:IPR036259|mint:P11169|rcsb pdb:4ZW9|rcsb pdb:4ZWB|rcsb pdb:4ZWC|rcsb pdb:5C65|rcsb pdb:7CRZ|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-6798695|reactome:R-HSA-9022699|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002945(Glucose transporter GLUT3, type 3)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:4lvD/2COzfHcIKxN1l9FsXOJWnk9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:610DDB962E292F50|rigid:QYE6i1DUYamEB72WYx66vLfGl9o	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P31946	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575852|imex:IM-24624-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	intact-crc:3C194EC1DB55D861|rigid:bqUZLTNXpvDhlEjkmXz5+jTFWmQ	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P50402	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575834|imex:IM-24624-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	intact-crc:0869814F8B312A54|rigid:GqGcJwEqPUXMWv2mMkD2wgaDHs8	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:B2RTY4	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-355398|uniprotkb:B0I1T5|uniprotkb:Q14787|uniprotkb:Q3YLD7|uniprotkb:Q3YLD8|uniprotkb:Q6P986|uniprotkb:Q9H8T5|uniprotkb:Q9NTG2|uniprotkb:Q9NUY2|uniprotkb:Q9UEP3|intact:EBI-720284|uniprotkb:Q9UNJ2|uniprotkb:C9IYB3|uniprotkb:C9JA86|intact:EBI-28974247|ensembl:ENSP00000348349|ensembl:ENSP00000398250	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:myo9a_human(display_long)|uniprotkb:MYO9A(gene name)|psi-mi:MYO9A(display_short)|uniprotkb:MYR7(gene name synonym)|uniprotkb:Unconventional myosin-9a(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575825|imex:IM-24624-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_008832.2|ensembl:ENSP00000348349|ensembl:ENST00000424560|ensembl:ENSP00000399162|ensembl:ENSP00000398250|refseq:XP_006720602.1|ensembl:ENSG00000066933(gene)|ensembl:ENST00000356056(transcript)|ensembl:ENST00000444904(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0034329"(cell junction assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028558|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013424	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:xiEo+vK0qu9k1RrBjoOrgp7Wm+g9606	intact-crc:336E88A60688817B|rigid:w1NXnJCHjmmkvvZo6E+IaJNdtqI	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15260	uniprotkb:P48039	intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575843|imex:IM-24624-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:09DC9FDCC9B5493A|rigid:337Mo4lgbQIBxYnCPEsyIiA1L0Q	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23468	uniprotkb:P48039	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575880|imex:IM-24624-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/16	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:A591A32E4BAF2D42|rigid:w/ds+m+XZ5C6a9iIHBhQR41ZM14	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P30519	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-712096|uniprotkb:I3L430|ensembl:ENSP00000219700|ensembl:ENSP00000381595|ensembl:ENSP00000385100|ensembl:ENSP00000391637|ensembl:ENSP00000394103|ensembl:ENSP00000459214|ensembl:ENSP00000478785|ensembl:ENSP00000481295|ensembl:ENSP00000481811|ensembl:ENSP00000483319|ensembl:ENSP00000484422|ensembl:ENSP00000484423|ensembl:ENSP00000484467|ensembl:ENSP00000487673|ensembl:ENSP00000488579|ensembl:ENSP00000488880|uniprotkb:O60605|uniprotkb:A8MT35|uniprotkb:D3DUD5	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:hmox2_human(display_long)|uniprotkb:HMOX2(gene name)|psi-mi:HMOX2(display_short)|uniprotkb:HO2(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575889|imex:IM-24624-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001273196.1|refseq:NP_001273197.1|refseq:NP_001273198.1|refseq:NP_001273199.1|refseq:NP_001273200.1|ensembl:ENSG00000103415(gene)|ensembl:ENSG00000277424(gene)|ensembl:ENST00000219700(transcript)|ensembl:ENST00000398595(transcript)|ensembl:ENST00000406590(transcript)|ensembl:ENST00000414777(transcript)|ensembl:ENST00000458134(transcript)|ensembl:ENST00000570646(transcript)|ensembl:ENST00000612525(transcript)|ensembl:ENST00000615778(transcript)|ensembl:ENST00000619528(transcript)|ensembl:ENST00000619913(transcript)|ensembl:ENST00000620445(transcript)|ensembl:ENST00000621065(transcript)|ensembl:ENST00000622146(transcript)|ensembl:ENST00000631540(transcript)|ensembl:ENST00000631677(transcript)|ensembl:ENST00000632458(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006788"(heme oxidation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042167"(heme catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|rcsb pdb:4WMH|rcsb pdb:5UC8|rcsb pdb:5UC9|rcsb pdb:5UCA|reactome:R-HSA-189483|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-917937|reactome:R-HSA-9707564|mint:P30519|rcsb pdb:2Q32|rcsb pdb:2QPP|rcsb pdb:2RGZ|refseq:NP_001120676.1|refseq:NP_001120677.1|refseq:NP_001120678.1|refseq:NP_002125.3|refseq:XP_016878685.1|refseq:XP_016878686.1|dip:DIP-53564N	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:yTwXdEjnQgfiFBvl5fhcCwDOJWo9606	intact-crc:171931962E292EA4|rigid:TFV1WSV2Xelil/n3I4smF2FVe5M	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:O15321	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1390491|uniprotkb:Q96FI8|uniprotkb:D3DS65|uniprotkb:Q86SZ6|intact:EBI-28976916|ensembl:ENSP00000261789|ensembl:ENSP00000494320	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:tm9s1_human(display_long)|uniprotkb:TM9SF1(gene name)|psi-mi:TM9SF1(display_short)|uniprotkb:MP70 protein family member(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575861|imex:IM-24624-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001014842.1|refseq:NP_006396.2|ensembl:ENSP00000494320|ensembl:ENSP00000261789|ensembl:ENST00000396854|ensembl:ENSP00000380063|ensembl:ENST00000646500|ensembl:ENSP00000494851|refseq:NP_001275935.1|ensembl:ENSG00000100926(gene)|ensembl:ENSG00000285465(gene)|ensembl:ENST00000261789(transcript)|ensembl:ENST00000646762(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)")	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:y4t2+OC3qVXBRLxyH65ywVx8Ja09606	intact-crc:8F47A66F528CB12E|rigid:Tp8D0vhDFKLRp8TBdt+kJRGZCFE	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q6GSK2	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11572624	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:q6gsk2_human(display_long)|uniprotkb:FDXR(gene name)|psi-mi:FDXR(display_short)|uniprotkb:hCG_29834(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575925|imex:IM-24624-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR021163|interpro:IPR023753|go:"GO:0005739"(mitochondrion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015039"(NADPH-adrenodoxin reductase activity)|interpro:IPR036188	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:92GnZ67Hkkcric4CcYdICc5kRHE9606	intact-crc:A15DDEBEFB24CA05|rigid:zdHq1a/adpEmMtFZoBxYrzHFRhk	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q6LEU9	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11572650	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:q6leu9_human(display_long)|uniprotkb:ATP5G3(gene name)|psi-mi:ATP5G3(display_short)|uniprotkb:ATPase protein 9(gene name synonym)|uniprotkb:ATPase subunit c(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575916|imex:IM-24624-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR000454(ATPase, F0 complex, subunit C)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR020537|interpro:IPR038662|go:"GO:0008289"(lipid binding)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|interpro:IPR035921	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:7IrEJL32MinpK5AKxKgbBDtyQg49606	intact-crc:A0951CC98FDD8457|rigid:57iL6iXWdol7g9onAjUUs3t9AKc	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6IBP4	uniprotkb:P48039	intact:EBI-11572637|uniprotkb:D6W522	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:q6ibp4_human(display_long)|uniprotkb:LAPTM4A(gene name)|psi-mi:LAPTM4A(display_short)|uniprotkb:hCG_32086(orf name)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575907|imex:IM-24624-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004687(Golgi 4-transmembrane spanning transporter)|interpro:IPR018396|refseq:NP_055528.1|go:"GO:0016021"(integral component of membrane)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:dPn0OwVfUAs214sLqb7eZHTViNk9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:15F913C20623841C|rigid:Ak1SDuELWcdOSSmg/pmM8sYBz3E	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P04406	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575898|imex:IM-24624-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism)	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606	intact-crc:4256AE3E24AA26B7|rigid:N7ONly90aRuXc3rvKu++MXa+jsQ	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q93052	uniprotkb:P48039	intact:EBI-718388|uniprotkb:D3DNV6|uniprotkb:Q8NFX5|uniprotkb:A1L4L6|ensembl:ENSP00000478901|ensembl:ENSP00000491657	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:lpp_human(display_long)|uniprotkb:LIM domain-containing preferred translocation partner in lipoma(gene name synonym)|uniprotkb:LPP(gene name)|psi-mi:LPP(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575943|imex:IM-24624-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001161143.1|refseq:NP_005569.1|refseq:XP_011511122.1|refseq:XP_011511129.1|refseq:XP_011511130.1|refseq:XP_011511133.1|refseq:XP_011511135.1|refseq:XP_016861866.1|refseq:XP_016861867.1|refseq:XP_016861868.1|refseq:XP_016861869.1|refseq:XP_011511136.1|refseq:XP_005247503.1|refseq:XP_005247507.1|refseq:XP_005247508.1|refseq:XP_005247510.1|ensembl:ENSG00000145012(gene)|ensembl:ENST00000617246(transcript)|ensembl:ENST00000640853(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0046872"(metal ion binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028771|mint:Q93052	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:1gZYhWdxZ0ogIkf0xrCOKZiAiyE9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:F905F83FBB60C4BC|rigid:LJHb25ifvr89csLlIVHgFGFW1tk	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q93077	uniprotkb:P48039	intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575952|imex:IM-24624-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:m00IdooZksbNGKHSsaVvGFVpcko9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:614528C8AFC744AC|rigid:INRRy48GcyBj/cxEfF4jMv43vX4	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q969W1	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11572692|uniprotkb:D3DR54|uniprotkb:Q8N4Z6|uniprotkb:D3DR52|uniprotkb:Q8WY84|uniprotkb:Q9BSV3|uniprotkb:D3DR53|uniprotkb:Q5JTH0|uniprotkb:Q5JTG7|ensembl:ENSP00000359891|ensembl:ENSP00000377357	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:zdh16_human(display_long)|uniprotkb:ZDHHC16(gene name)|psi-mi:ZDHHC16(display_short)|uniprotkb:Zinc finger DHHC domain-containing protein 16(gene name synonym)|uniprotkb:UNQ2570/PRO6258(orf name)|uniprotkb:APH2(gene name synonym)|uniprotkb:Abl-philin 2(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575961|imex:IM-24624-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:XP_016872255.1|refseq:XP_016872257.1|refseq:NP_001274732.1|refseq:NP_001274733.1|refseq:NP_115703.2|refseq:NP_932160.1|refseq:NP_932161.1|refseq:NP_932162.1|refseq:NP_932163.1|ensembl:ENSG00000171307(gene)|ensembl:ENST00000370854(transcript)|ensembl:ENST00000393760(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007507"(heart development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0021537"(telencephalon development)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR039859	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:hY2LEaNJ5yAfdDG1g6O/5gpZhlc9606	intact-crc:54FE5420E21ED328|rigid:P3IZSTD7TZ/rIguidPDZeBWXdOs	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q96A57	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-723971|uniprotkb:D3DVZ9|uniprotkb:Q0VGC8|uniprotkb:Q5TDS5|uniprotkb:Q96ES2|uniprotkb:Q9P0A7|uniprotkb:B2RDM8|ensembl:ENSP00000202834|ensembl:ENSP00000368579|ensembl:ENSP00000368581|ensembl:ENSP00000368585|ensembl:ENSP00000368588|ensembl:ENSP00000368601	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:tm230_human(display_long)|uniprotkb:TMEM230(gene name)|psi-mi:TMEM230(display_short)|uniprotkb:C20orf30(gene name synonym)|uniprotkb:HSPC274(orf name)|uniprotkb:UNQ2432/PRO4992(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575970|imex:IM-24624-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001009923.1|refseq:NP_001009924.1|refseq:NP_001009925.1|refseq:NP_054864.3|refseq:NP_001317913.1|refseq:NP_001317914.1|refseq:NP_001317915.1|refseq:XP_016883325.1|ensembl:ENSG00000089063(gene)|ensembl:ENST00000202834(transcript)|ensembl:ENST00000379277(transcript)|ensembl:ENST00000379279(transcript)|ensembl:ENST00000379283(transcript)|ensembl:ENST00000379286(transcript)|ensembl:ENST00000379299(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0055037"(recycling endosome)|interpro:IPR008590(Protein of unknown function DUF872, eukaryotic)|interpro:IPR044234	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:n9vIcFyub2Fl+lSnmvcQ1DrA7PE9606	intact-crc:A8332CC0E9899297|rigid:jsAbgS/jU+iap5Ono6azZSUb6NE	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q4G0S4	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11572612|uniprotkb:Q6ZNI7|uniprotkb:A0A590UJ17	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:c27c1_human(display_long)|uniprotkb:CYP27C1(gene name)|psi-mi:CYP27C1(display_short)|uniprotkb:All-trans retinol 3,4-desaturase(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575979|imex:IM-24624-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|refseq:NP_001001665.3|go:"GO:0001972"(retinoic acid binding)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005503"(all-trans retinal binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0020037"(heme binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042573"(retinoic acid metabolic process)|go:"GO:0042574"(retinal metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061896"(all-trans retinol 3,4-desaturase activity)|go:"GO:0061897"(all-trans retinal 3,4-desaturase activity)|go:"GO:0061898"(all-trans retinoic acid 3,4-desaturase activity)|go:"GO:0061899"(11-cis-retinal 3,4-desaturase activity)|go:"GO:1904768"(all-trans-retinol binding)|interpro:IPR036396	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2021/02/12	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:O3qaUORErbgbQqQ5wBcvcLS288I9606	intact-crc:574C41FF1201ED38|rigid:vbrZl2P21lm+yYdTjIyqxXO/Iek	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13495-3	uniprotkb:P48039	intact:EBI-11572588|ensembl:ENSP00000414517	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:q13495-3(display_long)|uniprotkb:MAMLD1(gene name)|psi-mi:MAMLD1(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:CXorf6(gene name synonym)|uniprotkb:F18(gene name synonym)|uniprotkb:Protein CG1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575934|imex:IM-24624-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11597050(isoform-parent)|ensembl:ENSG00000013619(gene)|ensembl:ENST00000432680(transcript)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:sAkM0BgBTAsChYJUfoeAJFQbMCw9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:1A901587B2199CF4|rigid:Cj54wnjZfmx9e6dTDPCoxHntvJk	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P21964	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-372265|uniprotkb:Q6IB07|uniprotkb:Q6ICE6|uniprotkb:A8MPV9|intact:EBI-743305|uniprotkb:Q9BWC7|intact:EBI-11576026|ensembl:ENSP00000354511|ensembl:ENSP00000384654|ensembl:ENSP00000385150|ensembl:ENSP00000385917|ensembl:ENSP00000503583|ensembl:ENSP00000503719|ensembl:ENSP00000504402	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:comt_human(display_long)|uniprotkb:COMT(gene name)|psi-mi:COMT(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576024|imex:IM-24624-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_000745.1|refseq:NP_001128633.1|refseq:NP_001128634.1|refseq:NP_009294.1|refseq:XP_016884083.1|refseq:XP_016884084.1|ensembl:ENSG00000093010(gene)|ensembl:ENST00000361682(transcript)|ensembl:ENST00000403710(transcript)|ensembl:ENST00000406520(transcript)|ensembl:ENST00000407537(transcript)|ensembl:ENST00000676678(transcript)|ensembl:ENST00000678255(transcript)|ensembl:ENST00000678868(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007565"(female pregnancy)|go:"GO:0007612"(learning)|go:"GO:0007614"(short-term memory)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|go:"GO:0016206"(catechol O-methyltransferase activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032259"(methylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032502"(developmental process)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042424"(catecholamine catabolic process)|go:"GO:0042493"|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043627"(response to estrogen)|go:"GO:0044297"(cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:0048265"(response to pain)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050668"(positive regulation of homocysteine metabolic process)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102084"(L-dopa O-methyltransferase activity)|go:"GO:0102938"(orcinol O-methyltransferase activity)|interpro:IPR002935(O-methyltransferase, family 3)|interpro:IPR017128(Catechol O-methyltransferase, eukaryotic)|interpro:IPR029063|mint:P21964|rcsb pdb:3A7E|rcsb pdb:3BWM|rcsb pdb:3BWY|rcsb pdb:4PYI|rcsb pdb:4PYJ|rcsb pdb:4PYK|rcsb pdb:4XUD|rcsb pdb:4XUE|rcsb pdb:5LSA|rcsb pdb:6I3C|rcsb pdb:6I3D|reactome:R-HSA-156581|reactome:R-HSA-379397|reactome:R-HSA-379398|reactome:R-HSA-9679191|rcsb pdb:4XUC	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/16	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:3Fnq8iVqPpOWNX6QQuiNRSsTFN09606	intact-crc:BF9081A5914EBE03|rigid:U0mkimDUFY25Y2sxsB3tjwxKA/0	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96D05	uniprotkb:P48039	intact:EBI-2548784|ensembl:ENSP00000362376	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:f241b_human(display_long)|uniprotkb:FAM241B(gene name)|psi-mi:FAM241B(display_short)|uniprotkb:C10orf35(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575988|imex:IM-24624-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171224(gene)|ensembl:ENST00000373279(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR027953|mint:Q96D05|refseq:XP_011537757.1|refseq:NP_660349.1|refseq:XP_005269663.1|refseq:XP_005269665.1|refseq:XP_016871325.1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:2Iylns4G5knUSJCXAPnLUE9laUU9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:75029E782307D8C1|rigid:KVgPcCZOfsxBN/Z3fm+ZB7bfosE	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75074	uniprotkb:P48039	intact:EBI-7866286|ensembl:ENSP00000253193|uniprotkb:B3KQD6|intact:MINT-201005|uniprotkb:B4DKF2	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:lrp3_human(display_long)|uniprotkb:LRP3(gene name)|psi-mi:LRP3(display_short)|uniprotkb:105 kDa low-density lipoprotein receptor-related protein(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11575997|imex:IM-24624-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000130881(gene)|ensembl:ENST00000253193(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|refseq:NP_002324.2	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	function:"Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro"|comment:mint	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:lUM1ZazzWN3c7hGaGfDnGZ1KgJU9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:51FFF1C9C8E476E5|rigid:mzYZzZKC4wk0NaC8FpYDZ42NfDc	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96NT1	uniprotkb:P48039	intact:EBI-713627|ensembl:ENSP00000320488|intact:EBI-5774422	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:np1l5_human(display_long)|uniprotkb:NAP1L5(gene name)|psi-mi:NAP1L5(display_short)|uniprotkb:DRLM(gene name synonym)|uniprotkb:Down-regulated in liver malignancy(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576006|imex:IM-24624-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177432(gene)|ensembl:ENST00000323061(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q96NT1|refseq:NP_715638.1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:VI8GuGWxjsUbTX2Yhi+57eb/hj49606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:8FF4296F368014B7|rigid:ixZ+Nvd1JgkIjlI2bXYHo86Sngw	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BT63	uniprotkb:P48039	intact:EBI-11572740	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:q9bt63_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576015|imex:IM-24624-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:XqY9SQoQp76ZO49U+lvfxXPCzCM9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:227D968AF1FB2504|rigid:pMMscdnG8ygrp8RfdyaS5P8Z0rs	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P05204	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1758689|uniprotkb:Q0VGD5|uniprotkb:Q6FGI5|uniprotkb:Q96C64|ensembl:ENSP00000355228|ensembl:ENSP00000481160	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:hmgn2_human(display_long)|uniprotkb:HMGN2(gene name)|psi-mi:HMGN2(display_short)|uniprotkb:HMG17(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 2(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576041|imex:IM-24624-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_005508.1|ensembl:ENSG00000198830(gene)|ensembl:ENST00000361427(transcript)|ensembl:ENST00000619352(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05204	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:j8Khsp7BUJh0L9SicpVNR8LP6ZU9606	intact-crc:9F2D96DDAA925072|rigid:KWZe63QSXwuKKEo9TyjwV70cYWo	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9NPA0	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576077|imex:IM-24624-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	intact-crc:53F228B4150A027E|rigid:1kyRm2tJufCggePLvTdwg/crUnw	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H4P4	uniprotkb:P48039	intact:EBI-2130266|uniprotkb:B2RBT8|uniprotkb:O75598|intact:EBI-2563208|intact:EBI-11576203|uniprotkb:A6NFW0|ensembl:ENSP00000342755|ensembl:ENSP00000447303|ensembl:ENSP00000484671	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:rnf41_human(display_long)|uniprotkb:RNF41(gene name)|psi-mi:RNF41(display_short)|uniprotkb:FLRF(gene name synonym)|uniprotkb:NRDP1(gene name synonym)|uniprotkb:RING finger protein 41(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NRDP1(gene name synonym)|uniprotkb:SBBI03(orf name)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576068|imex:IM-24624-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011536036.1|refseq:XP_011536037.1|refseq:NP_001229755.1|refseq:NP_005776.1|refseq:NP_919340.1|refseq:NP_919339.1|refseq:XP_005268618.1|ensembl:ENSG00000181852(gene)|ensembl:ENST00000345093(transcript)|ensembl:ENST00000552656(transcript)|ensembl:ENST00000615206(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015036(USP8 interacting)|interpro:IPR017907|interpro:IPR037255|rcsb pdb:2FZP|rcsb pdb:2GWF|reactome:R-HSA-1358803|reactome:R-HSA-983168	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:jthVZwxUECSdqeJ2jZQ5UL28kDY9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:FD8AEC7D67339CB3|rigid:zqofrrefZS//EnIY5mu6yd3PY8I	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P07437	uniprotkb:P48039	intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576050|imex:IM-24624-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:383119B55C1DE7B5|rigid:T5VC9v4afSqOA0L6bazgBLBh1Ec	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86VP6	uniprotkb:P48039	intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576059|imex:IM-24624-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060918.2|dip:DIP-31608N|ensembl:ENSG00000111530(gene)|ensembl:ENST00000545606(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|interpro:IPR016024(Armadillo-type fold)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:B9C14787D361DEA6|rigid:hV3IMcAlKI+UoSdnqZeDo2d2Y+8	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P35716	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11572540|uniprotkb:Q4ZFV8|ensembl:ENSP00000322568	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:sox11_human(display_long)|uniprotkb:SOX11(gene name)|psi-mi:SOX11(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576131|imex:IM-24624-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_003099.1|ensembl:ENSG00000176887(gene)|ensembl:ENST00000322002(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001822"(kidney development)|go:"GO:0001841"(neural tube formation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003211"(cardiac ventricle formation)|go:"GO:0003357"(noradrenergic neuron differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0021510"(spinal cord development)|go:"GO:0021782"(glial cell development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0050672"(negative regulation of lymphocyte proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060174"(limb bud formation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061053"(somite development)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0061386"(closure of optic fissure)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001111"(positive regulation of lens epithelial cell proliferation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017386(SOX-12/11/4a)|interpro:IPR029551|interpro:IPR036910|rcsb pdb:6T78|rcsb pdb:6T7A|rcsb pdb:6T7C|rcsb pdb:6T7D|go:"GO:0060563"(neuroepithelial cell differentiation)	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:IXRk1kjS4+gOT/MfchWginwvEKo9606	intact-crc:FD5F07E5491CFD90|rigid:9Ph7K+vnZWLz2euohksbrZlJSWU	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96M02	uniprotkb:P48039	intact:EBI-6152728|uniprotkb:Q8WU75|uniprotkb:Q5JRP6|uniprotkb:Q5T023|uniprotkb:B9EIQ9|uniprotkb:Q8NCV5|ensembl:ENSP00000284694	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:cj090_human(display_long)|uniprotkb:FATS(gene name synonym)|uniprotkb:Fragile-site associated tumor suppressor homolog(gene name synonym)|uniprotkb:C10orf90(gene name)|psi-mi:C10orf90(display_short)|uniprotkb:Centrosomal protein C10orf90(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase FATS(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576122|imex:IM-24624-42	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001004298.2|ensembl:ENSG00000154493(gene)|ensembl:ENST00000284694(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008017"(microtubule binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR029299|interpro:IPR029561|interpro:IPR041179	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:naG3fB3XXfhnbCczHW8FaDcX42c9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:B061BD13BFF81B88|rigid:SvCUpPizsOpisiZ6jeUjyeyDr3M	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P0B6	uniprotkb:P48039	intact:EBI-9083477|uniprotkb:Q5T7F7|uniprotkb:Q9BTQ9|ensembl:ENSP00000362507	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:cc167_human(display_long)|uniprotkb:CCDC167(gene name)|psi-mi:CCDC167(display_short)|uniprotkb:C6orf129(gene name synonym)|uniprotkb:HSPC265(orf name)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576113|imex:IM-24624-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612502.1|ensembl:ENSG00000198937(gene)|ensembl:ENST00000373408(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR028194	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:el6K1I4AQwH3OgjfL0EgIJmQjVc9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:95824B95C43F125A|rigid:dAabEaqZzpTAoBa+eaLf/vrxMso	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NYZ1	uniprotkb:P48039	intact:EBI-11343401|uniprotkb:A8K448|uniprotkb:Q9Y3E6|uniprotkb:Q96HK5|ensembl:ENSP00000305654	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:tv23b_human(display_long)|uniprotkb:TVP23B(gene name)|psi-mi:TVP23B(display_short)|uniprotkb:FAM18B(gene name synonym)|uniprotkb:FAM18B1(gene name synonym)|uniprotkb:CGI-148(orf name)|uniprotkb:NPD008(orf name)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576104|imex:IM-24624-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001303848.1|refseq:NP_001303849.1|refseq:NP_001303850.1|refseq:NP_001303851.1|refseq:NP_001303852.1|refseq:NP_001303853.1|refseq:NP_057162.4|ensembl:ENSG00000171928(gene)|ensembl:ENST00000307767(transcript)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR008564(Protein of unknown function DUF846, eukaryotic)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:gxyJHSx9RYFnyhZFDzRLW8QwzmU9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:9439469A830E867E|rigid:Cm1KvqVqHZnhRcGo+YAEZz0QP0U	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9NRF8	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-740874|ensembl:ENSP00000352222|ensembl:ENSP00000369590|ensembl:ENSP00000401264|uniprotkb:Q9BRI0|uniprotkb:Q9H809|uniprotkb:Q9H8K9|uniprotkb:B3KWM2	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:pyrg2_human(display_long)|uniprotkb:UTP--ammonia ligase 2(gene name synonym)|uniprotkb:CTP synthetase 2(gene name synonym)|uniprotkb:CTPS2(gene name)|psi-mi:CTPS2(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576086|imex:IM-24624-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000047230(gene)|refseq:NP_001137474.1|refseq:NP_062831.3|refseq:NP_787055.1|ensembl:ENST00000359276(transcript)|ensembl:ENST00000380241(transcript)|ensembl:ENST00000443824(transcript)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|rcsb pdb:2V4U|rcsb pdb:2VKT|rcsb pdb:3IHL|rcsb pdb:6PK4|rcsb pdb:6PK7|reactome:R-HSA-499943|refseq:XP_006724566.1|refseq:XP_005274619.1	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:BU/tvZTUS1d42+j0qSGAg7ND25Y9606	intact-crc:501EF491972DAD85|rigid:2pl0E9N7dBbQTxa4fm6zu0wTR6E	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23508	uniprotkb:P48039	intact:EBI-307531|intact:EBI-28976081|ensembl:ENSP00000305617|uniprotkb:Q6ZR04|uniprotkb:D3DT05	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:crcm_human(display_long)|uniprotkb:MCC(gene name)|psi-mi:MCC(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576095|imex:IM-24624-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171444(gene)|ensembl:ENST00000302475(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR019536|interpro:IPR040171|mint:P23508|rcsb pdb:6MTU|rcsb pdb:6MTV|ensembl:ENSP00000305617|ensembl:ENST00000408903|ensembl:ENSP00000386227|refseq:NP_001078846.1|refseq:NP_002378.1|dip:DIP-27599N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:zvmoD6/L4gqN193+FUqkECxbiTQ9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:36BB584FE3B5BD86|rigid:S6uUvUrex7v7zXT2oKrgSj5ELmU	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y255	uniprotkb:P48039	intact:EBI-11572796|uniprotkb:Q9UI13|uniprotkb:B2R5F7|uniprotkb:Q9UJS9|uniprotkb:D6RD25|uniprotkb:Q549N2|ensembl:ENSP00000302114	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:prld1_human(display_long)|uniprotkb:25 kDa protein of relevant evolutionary and lymphoid interest(gene name synonym)|uniprotkb:PRELI(gene name synonym)|uniprotkb:Px19-like protein(gene name synonym)|uniprotkb:CGI-106(orf name)|uniprotkb:SBBI12(orf name)|uniprotkb:PRELID1(gene name)|psi-mi:PRELID1(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576167|imex:IM-24624-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001258757.1|refseq:NP_037369.1|go:"GO:0015914"(phospholipid transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097035"(regulation of membrane lipid distribution)|go:"GO:0120009"(intermembrane lipid transfer)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:2001140"(positive regulation of phospholipid transport)|interpro:IPR006797(MSF1)|interpro:IPR037365|rcsb pdb:6I3V|rcsb pdb:6I3Y|reactome:R-HSA-6803204|go:"GO:0010950"(positive regulation of endopeptidase activity)|ensembl:ENSG00000169230(gene)|ensembl:ENST00000303204(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007275"(multicellular organism development)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:OoXfGISGnKv3t2Ge2bKS7bg5ViM9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:D82F15D961C47471|rigid:geh+0pvaxQTl27XBzlvozG3rJe4	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q01959	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-6661445|ensembl:ENSP00000270349|ensembl:ENSP00000479597|uniprotkb:A2RUN4|uniprotkb:Q14996	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:sc6a3_human(display_long)|uniprotkb:SLC6A3(gene name)|psi-mi:SLC6A3(display_short)|uniprotkb:DAT1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576158|imex:IM-24624-46	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|mint:Q01959|reactome:R-HSA-379401|reactome:R-HSA-442660|reactome:R-HSA-5619081|reactome:R-HSA-5660724|ensembl:ENSG00000142319(gene)|ensembl:ENSG00000276996(gene)|ensembl:ENST00000270349(transcript)|ensembl:ENST00000621716(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|refseq:NP_001035.1|dip:DIP-41827N	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:mQKSGpeovNv4Sg8T2E3A8rVB2aY9606	intact-crc:60DC729404604655|rigid:IEygMzAmJEB3dKhb2fH+rh4h13E	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UN67	uniprotkb:P48039	intact:EBI-6308942|ensembl:ENSP00000239446|uniprotkb:Q96T99	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:pcdba_human(display_long)|uniprotkb:PCDHB10(gene name)|psi-mi:PCDHB10(display_short)|uniprotkb:UNQ1906/PRO4352(orf name)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576140|imex:IM-24624-44	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120324(gene)|ensembl:ENST00000239446(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0045202"(synapse)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR032455|refseq:NP_061753.1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:eDBO6rRJdTj1TzDUyXxX+iDJywo9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:3C8C9FDD5C683447|rigid:tVv6aeU1+RpbXuse39a8AK4ct9M	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63244	uniprotkb:P48039	intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576149|imex:IM-24624-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:D99ADE27EDA7A0D4|rigid:78AvZuJPIW6HqW17s+xNp6OMMRE	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H4P4	uniprotkb:P49286	intact:EBI-2130266|uniprotkb:B2RBT8|uniprotkb:O75598|intact:EBI-2563208|intact:EBI-11576203|uniprotkb:A6NFW0|ensembl:ENSP00000342755|ensembl:ENSP00000447303|ensembl:ENSP00000484671	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:rnf41_human(display_long)|uniprotkb:RNF41(gene name)|psi-mi:RNF41(display_short)|uniprotkb:FLRF(gene name synonym)|uniprotkb:NRDP1(gene name synonym)|uniprotkb:RING finger protein 41(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NRDP1(gene name synonym)|uniprotkb:SBBI03(orf name)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576210|imex:IM-24624-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011536036.1|refseq:XP_011536037.1|refseq:NP_001229755.1|refseq:NP_005776.1|refseq:NP_919340.1|refseq:NP_919339.1|refseq:XP_005268618.1|ensembl:ENSG00000181852(gene)|ensembl:ENST00000345093(transcript)|ensembl:ENST00000552656(transcript)|ensembl:ENST00000615206(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015036(USP8 interacting)|interpro:IPR017907|interpro:IPR037255|rcsb pdb:2FZP|rcsb pdb:2GWF|reactome:R-HSA-1358803|reactome:R-HSA-983168	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/16	rogid:jthVZwxUECSdqeJ2jZQ5UL28kDY9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:8465A35C075E170F|rigid:llCOnH0gin6PLk8dDDZprkGDzws	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q14055	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-714971|uniprotkb:B2RMP9|ensembl:ENSP00000361834	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:co9a2_human(display_long)|uniprotkb:COL9A2(gene name)|psi-mi:COL9A2(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576194|imex:IM-24624-50	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001843.1|ensembl:ENSG00000049089(gene)|ensembl:ENST00000372748(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005594"(collagen type IX trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|interpro:IPR008160(Collagen triple helix repeat)|rcsb pdb:5CTD|rcsb pdb:5CTI|rcsb pdb:5CVA|rcsb pdb:5CVB|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000178|reactome:R-HSA-419037|reactome:R-HSA-8948216|go:"GO:0062023"(collagen-containing extracellular matrix)|refseq:XP_006710428.1	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:0Kx1jiNZX2rCxsEjRo/tAh5E9c89606	intact-crc:1AAD186F87929ABB|rigid:91h+D8zUkWvjHIBFHnXR/d9oyzQ	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9Y6G1	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2800360|uniprotkb:B2R552|ensembl:ENSP00000211314	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:tm14a_human(display_long)|uniprotkb:C6orf73(gene name synonym)|uniprotkb:PTD011(orf name)|uniprotkb:TMEM14A(gene name)|psi-mi:TMEM14A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576185|imex:IM-24624-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENST00000211314(transcript)|refseq:NP_054770.1|ensembl:ENSG00000096092(gene)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|interpro:IPR005349(Protein of unknown function UPF0136, Transmembrane)|interpro:IPR044890|mint:Q9Y6G1|rcsb pdb:2LOO|rcsb pdb:2LOP|go:"GO:0005789"(endoplasmic reticulum membrane)	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:nrvzpoAjkgMJIDiqVIVa5b3jLsQ9606	intact-crc:35C054B0B34D5A0F|rigid:JKNMTc0NbRljXnOB4eo1gm6gsPo	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P11169	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-725116|uniprotkb:Q6I9U2|uniprotkb:Q9UG15|uniprotkb:D3DUU6|uniprotkb:B2R606|ensembl:ENSP00000075120	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:gtr3_human(display_long)|uniprotkb:Glucose transporter type 3, brain(gene name synonym)|uniprotkb:SLC2A3(gene name)|psi-mi:SLC2A3(display_short)|uniprotkb:GLUT3(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576219|imex:IM-24624-52	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_008862.1|ensembl:ENSG00000059804(gene)|ensembl:ENST00000075120(transcript)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005536"(glucose binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019852"(L-ascorbic acid metabolic process)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043204"(perikaryon)|interpro:IPR020846|interpro:IPR036259|mint:P11169|rcsb pdb:4ZW9|rcsb pdb:4ZWB|rcsb pdb:4ZWC|rcsb pdb:5C65|rcsb pdb:7CRZ|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-6798695|reactome:R-HSA-9022699|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002945(Glucose transporter GLUT3, type 3)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:4lvD/2COzfHcIKxN1l9FsXOJWnk9606	intact-crc:D73E79BFE3325C92|rigid:BsJCgSYSp/OLd7qj7Luyt32tkdA	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y320	uniprotkb:P48039	intact:EBI-6447886|ensembl:ENSP00000278422|uniprotkb:B7Z4R4|uniprotkb:Q8NBP9|uniprotkb:Q5J7Q7|uniprotkb:Q561W0|uniprotkb:Q53G73|uniprotkb:Q9H3L1|intact:EBI-7128726|intact:MINT-6945923	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:tmx2_human(display_long)|uniprotkb:Cell proliferation-inducing gene 26 protein(gene name synonym)|uniprotkb:TXNDC14(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 14(gene name synonym)|uniprotkb:CGI-31(orf name)|uniprotkb:My009(orf name)|uniprotkb:PIG26(orf name)|uniprotkb:PSEC0045(orf name)|uniprotkb:UNQ237/PRO270(orf name)|uniprotkb:TMX2(gene name)|psi-mi:TMX2(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576176|imex:IM-24624-48	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000213593(gene)|ensembl:ENST00000278422(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007420"(brain development)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR037463|interpro:IPR039101|mint:Q9Y320|rcsb pdb:2DJ0|refseq:NP_001137484.1|refseq:NP_057043.1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:5YbR806GhogQ2yI3r9uo8i97MzY9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:49156655DC033D10|rigid:ifdQCjRZqF0hNROm8gna+FAHZmA	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:E1B2J3	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11572841	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:e1b2j3_human(display_long)|uniprotkb:MECP2(gene name)|psi-mi:MECP2(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576228|imex:IM-24624-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:L/L6TXdPZgpBFFd0r0Rt4ok2AO09606	intact-crc:91E5D33F8C2678E3|rigid:loJ0eJmVOuTX0z2TXV0zUKY/RD4	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14521	uniprotkb:P49286	intact:EBI-1224553|uniprotkb:Q6IRW2|uniprotkb:A6ND90|uniprotkb:Q53XW5|uniprotkb:B3KQQ8|uniprotkb:E9PIG3|uniprotkb:E9PQI9|uniprotkb:E9PIC0|ensembl:ENSP00000364699	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:dhsd_human(display_long)|uniprotkb:SDHD(gene name)|psi-mi:SDHD(display_short)|uniprotkb:SDH4(gene name synonym)|uniprotkb:Succinate-ubiquinone reductase membrane anchor subunit(gene name synonym)|uniprotkb:QPs3(gene name synonym)|uniprotkb:CII-4(gene name synonym)|uniprotkb:Succinate dehydrogenase complex subunit D(gene name synonym)|uniprotkb:Succinate-ubiquinone oxidoreductase cytochrome b small subunit(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576237|imex:IM-24624-54	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002993.1|refseq:NP_001263432.1|refseq:NP_001263433.1|refseq:NP_001263435.1|ensembl:ENSG00000204370(gene)|ensembl:ENST00000375549(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|interpro:IPR007992(CybS)|interpro:IPR034804|reactome:R-HSA-611105|reactome:R-HSA-71403	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:2JucMsDipYcRTQDCAO+aHdMrV709606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:2DC2A07CDC33F8AE|rigid:V1x0McMtyWY56h7//KKMNT6iHzo	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96A57	uniprotkb:P49286	intact:EBI-723971|uniprotkb:D3DVZ9|uniprotkb:Q0VGC8|uniprotkb:Q5TDS5|uniprotkb:Q96ES2|uniprotkb:Q9P0A7|uniprotkb:B2RDM8|ensembl:ENSP00000202834|ensembl:ENSP00000368579|ensembl:ENSP00000368581|ensembl:ENSP00000368585|ensembl:ENSP00000368588|ensembl:ENSP00000368601	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:tm230_human(display_long)|uniprotkb:TMEM230(gene name)|psi-mi:TMEM230(display_short)|uniprotkb:C20orf30(gene name synonym)|uniprotkb:HSPC274(orf name)|uniprotkb:UNQ2432/PRO4992(orf name)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576246|imex:IM-24624-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009923.1|refseq:NP_001009924.1|refseq:NP_001009925.1|refseq:NP_054864.3|refseq:NP_001317913.1|refseq:NP_001317914.1|refseq:NP_001317915.1|refseq:XP_016883325.1|ensembl:ENSG00000089063(gene)|ensembl:ENST00000202834(transcript)|ensembl:ENST00000379277(transcript)|ensembl:ENST00000379279(transcript)|ensembl:ENST00000379283(transcript)|ensembl:ENST00000379286(transcript)|ensembl:ENST00000379299(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0055037"(recycling endosome)|interpro:IPR008590(Protein of unknown function DUF872, eukaryotic)|interpro:IPR044234	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:n9vIcFyub2Fl+lSnmvcQ1DrA7PE9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:C3E83A31C798D160|rigid:Zm+52bkP01JTE8E02AyOT5qznBo	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P31946	uniprotkb:P49286	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576255|imex:IM-24624-56	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:8A2AECE8164EABA3|rigid:26mAaxT+2Rb/hqqM15O7YBAngH8	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P08195	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576273|imex:IM-24624-58	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	intact-crc:60631BB693A629FE|rigid:XdWbqPqhhwnALmSs+ihYTZvROto	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9UJ14	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1058791|ensembl:ENSP00000338964|uniprotkb:Q8N899|uniprotkb:Q8NF66|uniprotkb:Q9BYP5|uniprotkb:Q9BYP6	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ggt7_human(display_long)|uniprotkb:GGT7(gene name)|psi-mi:GGT7(display_short)|uniprotkb:GGTL3(gene name synonym)|uniprotkb:GGTL5(gene name synonym)|uniprotkb:Gamma-glutamyltranspeptidase 7(gene name synonym)|uniprotkb:Gamma-glutamyltransferase-like 3(gene name synonym)|uniprotkb:Gamma-glutamyltransferase-like 5(gene name synonym)|uniprotkb:Gamma-glutamyltransferase 7(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576264|imex:IM-24624-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_821158.2|ensembl:ENSG00000131067(gene)|ensembl:ENST00000336431(transcript)|go:"GO:0000048"(peptidyltransferase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0006751"(glutathione catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0036374"(glutathione hydrolase activity)|go:"GO:0102953"(hypoglycin A gamma-glutamyl transpeptidase activity)|go:"GO:0103068"(leukotriene C4 gamma-glutamyl transferase activity)|go:"GO:1901750"(leukotriene D4 biosynthetic process)|go:"GO:1902883"(negative regulation of response to oxidative stress)|interpro:IPR000101(Gamma-glutamyltranspeptidase)|interpro:IPR029055|interpro:IPR043137|interpro:IPR043138|reactome:R-HSA-174403|reactome:R-HSA-5423646	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:gAPBdehRHCbx1QWo/NmujxXx9hc9606	intact-crc:761C62B5F0C0B36E|rigid:VoQRHV7f0lLvEywyuf3yf0CNZY8	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9GZU8	uniprotkb:P49286	intact:EBI-2371956|ensembl:ENSP00000335808|ensembl:ENSP00000374098|ensembl:ENSP00000456211|ensembl:ENSP00000457740|ensembl:ENSP00000457850	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:pip30_human(display_long)|uniprotkb:PSME3IP1(gene name)|psi-mi:PSME3IP1(display_short)|uniprotkb:C16orf94(gene name synonym)|uniprotkb:FAM192A(gene name synonym)|uniprotkb:NEFA-interacting nuclear protein NIP30(gene name synonym)|uniprotkb:NIP30(gene name synonym)|uniprotkb:PA28G-interacting protein(gene name synonym)|uniprotkb:PIP30(gene name synonym)|uniprotkb:CDA018(orf name)|uniprotkb:CDA10(orf name)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576291|imex:IM-24624-60	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011521645.1|refseq:NP_079222.1|refseq:XP_005256217.1|refseq:XP_005256220.1|refseq:XP_005256221.1|refseq:XP_005256222.1|refseq:XP_016879171.1|refseq:XP_016879172.1|refseq:XP_016879173.1|refseq:XP_016879174.1|refseq:XP_016879175.1|refseq:XP_016879176.1|refseq:XP_016879177.1|refseq:XP_016879178.1|refseq:XP_016879179.1|refseq:XP_016879180.1|refseq:XP_016879181.1|refseq:XP_016879182.1|refseq:XP_016879183.1|refseq:XP_016879184.1|refseq:XP_016879185.1|refseq:XP_016879186.1|refseq:XP_016879187.1|refseq:XP_016879188.1|refseq:XP_016879189.1|refseq:XP_016879190.1|refseq:XP_016879191.1|refseq:XP_016879192.1|refseq:XP_016879193.1|ensembl:ENSG00000172775(gene)|ensembl:ENST00000309137(transcript)|ensembl:ENST00000389447(transcript)|ensembl:ENST00000564108(transcript)|ensembl:ENST00000567439(transcript)|ensembl:ENST00000569266(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR019331|interpro:IPR039845|mint:Q9GZU8	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:L6twOcOqRARWRz4Em7oxxyLGsL09606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:355182000EF28FB1|rigid:k/OKhNwYExGaT2CK1zA9T/3msb4	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UN67	uniprotkb:P49286	intact:EBI-6308942|ensembl:ENSP00000239446|uniprotkb:Q96T99	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:pcdba_human(display_long)|uniprotkb:PCDHB10(gene name)|psi-mi:PCDHB10(display_short)|uniprotkb:UNQ1906/PRO4352(orf name)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576282|imex:IM-24624-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120324(gene)|ensembl:ENST00000239446(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0045202"(synapse)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR032455|refseq:NP_061753.1	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:eDBO6rRJdTj1TzDUyXxX+iDJywo9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:5757892C727977B0|rigid:oGg96zN2ccZqa4CrztlMYRfhWgo	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9GZY8	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11420856|uniprotkb:Q567U1|uniprotkb:Q658R6|uniprotkb:Q9BVZ1|uniprotkb:Q9H690|uniprotkb:Q9NRG8|ensembl:ENSP00000302037	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:mff_human(display_long)|uniprotkb:MFF(gene name)|psi-mi:MFF(display_short)|uniprotkb:C2orf33(gene name synonym)|uniprotkb:AD030(orf name)|uniprotkb:AD033(orf name)|uniprotkb:GL004(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576300|imex:IM-24624-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001263990.1|refseq:NP_001263991.1|refseq:NP_001263992.1|refseq:NP_001263993.1|refseq:NP_001263994.1|refseq:NP_001263995.1|refseq:NP_001263996.1|refseq:NP_001263997.1|refseq:NP_064579.3|refseq:XP_006712701.1|refseq:XP_006712702.1|refseq:XP_011509802.1|ensembl:ENSG00000168958(gene)|ensembl:ENST00000353339(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR008518(Protein of unknown function DUF800)|interpro:IPR039433|refseq:XP_016860004.1	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:TwZhnkjdZZZrKu3VDUd4BvgXmRc9606	intact-crc:4EDF2F79DF494BCC|rigid:0uZItT1icpl5DaAW5D/XmKuY+kI	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9Y6G1	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-2800360|uniprotkb:B2R552|ensembl:ENSP00000211314	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:tm14a_human(display_long)|uniprotkb:C6orf73(gene name synonym)|uniprotkb:PTD011(orf name)|uniprotkb:TMEM14A(gene name)|psi-mi:TMEM14A(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576327|imex:IM-24624-64	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENST00000211314(transcript)|refseq:NP_054770.1|ensembl:ENSG00000096092(gene)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|interpro:IPR005349(Protein of unknown function UPF0136, Transmembrane)|interpro:IPR044890|mint:Q9Y6G1|rcsb pdb:2LOO|rcsb pdb:2LOP|go:"GO:0005789"(endoplasmic reticulum membrane)	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:nrvzpoAjkgMJIDiqVIVa5b3jLsQ9606	intact-crc:5E1B42419D5C19F8|rigid:XcKO4PrfU9aiuMRMhTfsU8t9RGg	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q15125	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-3915253|uniprotkb:Q6IBI9|uniprotkb:Q6FGL3|ensembl:ENSP00000417052	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ebp_human(display_long)|uniprotkb:EBP(gene name)|psi-mi:EBP(display_short)|uniprotkb:Cholestenol Delta-isomerase(gene name synonym)|uniprotkb:"Delta(8)-Delta(7) sterol isomerase"(gene name synonym)|uniprotkb:Emopamil-binding protein(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576336|imex:IM-24624-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_006570.1|ensembl:ENSG00000147155(gene)|ensembl:ENST00000495186(transcript)|go:"GO:0000247"(C-8 sterol isomerase activity)|go:"GO:0001501"(skeletal system development)|go:"GO:0004769"(steroid delta-isomerase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0047750"(cholestenol delta-isomerase activity)|interpro:IPR007905(Emopamil-binding)|interpro:IPR033118|rcsb pdb:6OHT|rcsb pdb:6OHU|reactome:R-HSA-6807047|reactome:R-HSA-6807062	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:7XfeeD/twqYll0Hv4YuJUbmAVJ09606	intact-crc:532FC1D03E62620D|rigid:wxmPx2LKdhifQdoiShK0lhWdTWc	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6FII3	uniprotkb:P49286	intact:EBI-11572930	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:q6fii3_human(display_long)|uniprotkb:hCG_21643(orf name)|uniprotkb:C14orf1(gene name)|psi-mi:C14orf1(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576345|imex:IM-24624-66	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR005352(Erg28-like)|refseq:NP_009107.1|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:byHFBrxoQGC/b8Lcd+ey5ibxZCM9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:C49731C1A9E0CDD9|rigid:pi+E9kBF44Nyt76zoyL5pK+ICF8	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9NY35	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-4319704|uniprotkb:B3KQR1|uniprotkb:D3DN36|uniprotkb:Q502Y8|uniprotkb:Q6UVX2|uniprotkb:Q9BUZ9|uniprotkb:Q9NZZ5|uniprotkb:Q9Y4S9|uniprotkb:F2Z2D9|ensembl:ENSP00000340247|ensembl:ENSP00000377734|ensembl:ENSP00000377739|ensembl:ENSP00000421226|ensembl:ENSP00000423590|ensembl:ENSP00000426869	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:cldn1_human(display_long)|uniprotkb:CLDND1(gene name)|psi-mi:CLDND1(display_short)|uniprotkb:C3orf4(gene name synonym)|uniprotkb:Membrane protein GENX-3745(gene name synonym)|uniprotkb:HSPC174(orf name)|uniprotkb:PSEC0054(orf name)|uniprotkb:UNQ2511/PRO6000(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576309|imex:IM-24624-62	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001035271.1|refseq:NP_001035272.1|refseq:NP_001035273.1|refseq:NP_001035289.1|refseq:NP_063948.1|refseq:NP_001035290.1|ensembl:ENSG00000080822(gene)|ensembl:ENST00000341181(transcript)|ensembl:ENST00000394180(transcript)|ensembl:ENST00000394185(transcript)|ensembl:ENST00000503004(transcript)|ensembl:ENST00000510545(transcript)|ensembl:ENST00000513287(transcript)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|mint:Q9NY35|interpro:IPR042356	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:CNmeJrYJHY7m8TRdvFpUcASQujk9606	intact-crc:3E8A9ACB7FC0FB51|rigid:C+7ntm8XWsUZ7WmSQszbc0Upuxs	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P10827	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-286285|uniprotkb:P21205|uniprotkb:Q8N6A1|uniprotkb:Q96H73|uniprotkb:A8K3B5|ensembl:ENSP00000264637|ensembl:ENSP00000377679	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:tha_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group A member 1(gene name synonym)|uniprotkb:EAR7(gene name synonym)|uniprotkb:c-erbA-1(gene name synonym)|uniprotkb:c-erbA-alpha(gene name synonym)|uniprotkb:THRA(gene name)|psi-mi:THRA(display_short)|uniprotkb:ERBA1(gene name synonym)|uniprotkb:NR1A1(gene name synonym)|uniprotkb:THRA1(gene name synonym)|uniprotkb:THRA2(gene name synonym)|uniprotkb:V-erbA-related protein 7(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576318|imex:IM-24624-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001177847.1|refseq:NP_001177848.1|refseq:NP_003241.2|refseq:NP_955366.1|dip:DIP-31452N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007611"(learning or memory)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008050"(female courtship behavior)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009409"(response to cold)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0033032"(regulation of myeloid cell apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000143"(negative regulation of DNA-templated transcription, initiation)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1NAV|rcsb pdb:2H77|rcsb pdb:2H79|rcsb pdb:3HZF|rcsb pdb:3ILZ|rcsb pdb:3JZB|rcsb pdb:4LNW|rcsb pdb:4LNX|reactome:R-HSA-383280|reactome:R-HSA-4090294|ensembl:ENSG00000126351(gene)|ensembl:ENST00000264637(transcript)|ensembl:ENST00000394121(transcript)	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:u1B3u6XbEyC3OKOWr25s9qZYe4o9606	intact-crc:D243F1376BB93FC4|rigid:+XnS4d06QCiRkIlTQojdN+twng0	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P23468	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576354|imex:IM-24624-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/16	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	intact-crc:CE4AB5DF65BE6EB5|rigid:nposymtRTkkASnQCbhEQbl+ZsjY	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q4VBN9	uniprotkb:P49286	intact:EBI-11572919	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:q4vbn9_human(display_long)|uniprotkb:DARC(gene name)|psi-mi:DARC(display_short)|uniprotkb:Duffy antigen/chemokine receptor(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576378|imex:IM-24624-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR005384(Duffy antigen/chemokine receptor)|go:"GO:0006954"(inflammatory response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019956"(chemokine binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0070098"(chemokine-mediated signaling pathway)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:MoB2vImJG0RdvCZ+uPCeP51r8Ow9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:3C2FF5462A44D693|rigid:AUf2LdbTGTw4SPV9NgXYIjG/5RE	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13491	uniprotkb:P49286	intact:EBI-4397339|uniprotkb:O76077|uniprotkb:Q86X43|uniprotkb:Q8N956|ensembl:ENSP00000349420	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:gpm6b_human(display_long)|uniprotkb:GPM6B(gene name)|psi-mi:GPM6B(display_short)|uniprotkb:M6B(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576387|imex:IM-24624-70	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001994.1|refseq:NP_001001995.1|refseq:NP_001001996.1|refseq:NP_005269.1|ensembl:ENSG00000046653(gene)|ensembl:ENST00000356942(transcript)|go:"GO:0001503"(ossification)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0051612"(negative regulation of serotonin uptake)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0085029"(extracellular matrix assembly)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|go:"GO:0015031"(protein transport)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:eNSbjdvVOvvLIowS7p8EZ9TIj0Q9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:AF3E955509BD9BBD|rigid:64dhyETCsUtgLaE1n5KehYWV23g	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9H169	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-722971|uniprotkb:B7Z2Z7|uniprotkb:Q2TAB9|uniprotkb:D3DSS8|uniprotkb:D3DSS9|uniprotkb:B7Z4I9|uniprotkb:G5EA16|ensembl:ENSP00000265770	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:stmn4_human(display_long)|uniprotkb:Stathmin-like protein B3(gene name synonym)|uniprotkb:STMN4(gene name)|psi-mi:STMN4(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576396|imex:IM-24624-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001269983.1|refseq:NP_110422.2|refseq:NP_001269982.1|refseq:NP_001269984.1|ensembl:ENSG00000015592(gene)|ensembl:ENST00000265770(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0015631"(tubulin binding)|go:"GO:0030426"(growth cone)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|interpro:IPR000956(Stathmin)|interpro:IPR028834|interpro:IPR030514|interpro:IPR036002|mint:Q9H169|rcsb pdb:6BR1|rcsb pdb:6BRF|rcsb pdb:6BRY|rcsb pdb:6NNG|rcsb pdb:6O5M|rcsb pdb:6O5N|rcsb pdb:6O61|rcsb pdb:6PC4	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:Nz8GpnGi0yiq5hg9L9dn/eI10ag9606	intact-crc:132389BBD4633B4E|rigid:fR1cuR1FqFAl9T9jCFSoj0HzMkM	false	cub:?-?	nubg:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UNA4	uniprotkb:P49286	intact:EBI-741774|ensembl:ENSP00000462664|uniprotkb:Q8N590|uniprotkb:Q9H0S1|uniprotkb:Q9NYH6	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:poli_human(display_long)|uniprotkb:Eta2(gene name synonym)|uniprotkb:RAD30 homolog B(gene name synonym)|uniprotkb:POLI(gene name)|psi-mi:POLI(display_short)|uniprotkb:RAD30B(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576405|imex:IM-24624-72	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1T3N|rcsb pdb:1ZET|rcsb pdb:2ALZ|rcsb pdb:2DPI|rcsb pdb:2DPJ|rcsb pdb:2FLL|rcsb pdb:2FLN|rcsb pdb:2FLP|rcsb pdb:2KHU|rcsb pdb:2KHW|rcsb pdb:2KTF|rcsb pdb:2L0F|rcsb pdb:2L0G|rcsb pdb:2MBB|rcsb pdb:3EPG|rcsb pdb:3EPI|rcsb pdb:3G6V|rcsb pdb:3G6X|rcsb pdb:3G6Y|rcsb pdb:3GV5|rcsb pdb:3GV7|rcsb pdb:3GV8|rcsb pdb:3H40|rcsb pdb:3H4B|rcsb pdb:3H4D|ensembl:ENSG00000101751(gene)|ensembl:ENST00000579534(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0016607"(nuclear speck)|go:"GO:0019985"(translesion synthesis)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR017961|interpro:IPR036775|interpro:IPR043128|interpro:IPR043502|mint:Q9UNA4|refseq:NP_009126.2|rcsb pdb:3NGD|rcsb pdb:3OSN|rcsb pdb:3Q8P|rcsb pdb:3Q8Q|rcsb pdb:3Q8R|rcsb pdb:3Q8S|rcsb pdb:4EBC|rcsb pdb:4EBD|rcsb pdb:4EBE|rcsb pdb:4EYI|rcsb pdb:4FS1|rcsb pdb:4FS2|rcsb pdb:5KT2|rcsb pdb:5KT3|rcsb pdb:5KT4|rcsb pdb:5KT5|rcsb pdb:5KT6|rcsb pdb:5KT7|rcsb pdb:5ULW|rcsb pdb:5ULX|reactome:R-HSA-5656121|reactome:R-HSA-5656169|rcsb pdb:4EYH	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:iH6WfDK+UIzw5XQSHo9wWSfnrJU9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:3D2AC6F8ECBEE832|rigid:hirj/DnbTeiN64WRAkDZltVTfZI	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99437	uniprotkb:P49286	intact:EBI-3904417|intact:EBI-11576363|uniprotkb:Q6IB32|uniprotkb:D3DPY5|ensembl:ENSP00000431605	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:vato_human(display_long)|uniprotkb:ATP6V0B(gene name)|psi-mi:ATP6V0B(display_short)|uniprotkb:ATP6F(gene name synonym)|uniprotkb:Vacuolar proton pump 21 kDa proteolipid subunit(gene name synonym)|uniprotkb:hATPL(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576369|imex:IM-24624-68	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001034546.1|refseq:NP_004038.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|mint:Q99437|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|ensembl:ENSG00000117410(gene)|ensembl:ENST00000472174(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0010008"(endosome membrane)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/17	rogid:p4ukhUJl2n4EOj6IOXmYz2zjm0Y9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:5C315FF1772A3514|rigid:JcionqKrNJXGjWfr3uc1B0va7R4	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z5L9	uniprotkb:P49286	intact:EBI-2857769|uniprotkb:B1AM36|uniprotkb:Q7Z5L8|uniprotkb:Q6P083|uniprotkb:Q8N351|uniprotkb:B1AM35|uniprotkb:Q8WUH8|ensembl:ENSP00000355568	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:i2bp2_human(display_long)|uniprotkb:IRF2BP2(gene name)|psi-mi:IRF2BP2(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576423|imex:IM-24624-74	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001070865.1|refseq:NP_892017.2|ensembl:ENSG00000168264(gene)|ensembl:ENST00000366609(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR022750|interpro:IPR044882	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:D7vDkesEqSEgGURqQ0LM7XhXdRk9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:2948385063D2CE36|rigid:hP3Yxfp0ox4tS2cRmxxbG+1VVPE	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P2K9	uniprotkb:P49286	intact:EBI-721461|uniprotkb:Q5VTU9|uniprotkb:Q9UJD6|ensembl:ENSP00000294484	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:disp3_human(display_long)|uniprotkb:DISP3(gene name)|psi-mi:DISP3(display_short)|uniprotkb:KIAA1337(gene name synonym)|uniprotkb:PTCHD2(gene name synonym)|uniprotkb:Patched domain-containing protein 2(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576414|imex:IM-24624-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065831.1|ensembl:ENSG00000204624(gene)|ensembl:ENST00000294484(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045834"(positive regulation of lipid metabolic process)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|interpro:IPR042480|refseq:XP_011540130.1	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:gKyA0p0/3iGiOKqyX8tc+Ml4HD89606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:6349976819B4505F|rigid:HyC+iFOjYHCpy1EoAAML0VTcy44	false	nubg:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P47199	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-8317381|ensembl:ENSMUSP00000029850|ensembl:ENSMUSP00000142105|uniprotkb:Q62508|intact:MINT-1862605|uniprotkb:Q99L63	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:qor_mouse(display_long)|uniprotkb:Cryz(gene name)|psi-mi:Cryz(display_short)|uniprotkb:"NADPH:quinone reductase"(gene name synonym)|uniprotkb:Zeta-crystallin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:XP_011238308.1|ensembl:ENSMUSG00000028199(gene)|ensembl:ENSMUST00000192462(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003960"("NADPH:quinone reductase activity")|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0050661"(NADP binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070402"(NADPH binding)|interpro:IPR002364(Quinone oxidoreductase/zeta-crystallin, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|mint:P47199|ensembl:ENSMUST00000029850(transcript)|refseq:NP_034098.1|refseq:XP_006501036.1	-	-	function:Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones are the best substrates. May act in the detoxification of xenobiotics|comment:mint	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:LurWfJoJpkY1t2H0OFtOk5+uNhQ10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9D358	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-8318198|ensembl:ENSMUSP00000106509|intact:MINT-1855654|uniprotkb:O88740|uniprotkb:O88739|uniprotkb:Q9QWF5	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:ppac_mouse(display_long)|uniprotkb:Acp1(gene name)|psi-mi:Acp1(display_short)|uniprotkb:Low molecular weight cytosolic acid phosphatase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSMUSG00000044573(gene)|ensembl:ENSMUST00000062740(transcript)|go:"GO:0003993"(acid phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0042383"(sarcolemma)|interpro:IPR002115(Protein-tyrosine phosphatase, low molecular weight, mammalian)|interpro:IPR017867|interpro:IPR023485|interpro:IPR036196|mint:Q9D358|rcsb pdb:2P4U|rcsb pdb:5JNU|refseq:NP_001103709.1|refseq:NP_067305.2	-	-	comment:mint|function:Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:kXRd56UxJ8VuIvs5bn7fmluGd+g10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P56399	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-8028688|intact:MINT-220667|ensembl:ENSMUSP00000041299	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:ubp5_mouse(display_long)|uniprotkb:Usp5(gene name)|psi-mi:Usp5(display_short)|uniprotkb:Isot(gene name synonym)|uniprotkb:Ubiquitin thioesterase 5(gene name synonym)|uniprotkb:Deubiquitinating enzyme 5(gene name synonym)|uniprotkb:Isopeptidase T(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001313523.1|refseq:NP_038728.1|ensembl:ENSMUSG00000038429(gene)|ensembl:ENSMUST00000047510(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0071108"(protein K48-linked deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR009060(UBA-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016652(Ubiquitinyl hydrolase)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|interpro:IPR041432|interpro:IPR041812|mint:P56399|reactome:R-MMU-5689880|reactome:R-MMU-8866652	-	-	comment:mint|function:Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:8ZmR4obS31RhQIm3bd2fZYAFZ8U10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P23298	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-8400924|uniprotkb:Q8K2K8|intact:MINT-4100035|ensembl:ENSMUSP00000021527	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:kpcl_mouse(display_long)|uniprotkb:Prkch(gene name)|psi-mi:Prkch(display_short)|uniprotkb:Pkch(gene name synonym)|uniprotkb:nPKC-eta(gene name synonym)|uniprotkb:PKC-L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001300906.1|refseq:NP_032882.2|ensembl:ENSMUSG00000021108(gene)|ensembl:ENSMUST00000021527(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050861"(positive regulation of B cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027431|interpro:IPR034665|interpro:IPR035892|mint:P23298|reactome:R-MMU-114508	-	-	comment:mint|function:PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters|function:This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:s3JUfxmbABf5gHbXKnlMrKCEcmg10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P45591	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-8313728|ensembl:ENSMUSP00000077262|intact:MINT-1869247	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:cof2_mouse(display_long)|uniprotkb:Cfl2(gene name)|psi-mi:Cfl2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSMUSG00000062929(gene)|ensembl:ENSMUST00000078124(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:P45591|refseq:NP_031714.1	-	-	comment:mint|function:"Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods"	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:IGCzZg3kPYp44b0TRKSQJxsE5QA10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9D7X3	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-8320546|intact:MINT-4093702|ensembl:ENSMUSP00000003612|ensembl:ENSMUSP00000102790	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:dus3_mouse(display_long)|uniprotkb:Dusp3(gene name)|psi-mi:Dusp3(display_short)|uniprotkb:T-DSP11(gene name synonym)|uniprotkb:Vaccinia H1-related phosphatase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_082483.1|ensembl:ENSMUSG00000003518(gene)|ensembl:ENSMUST00000003612(transcript)|ensembl:ENSMUST00000107172(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001772"(immunological synapse)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033549"(MAP kinase phosphatase activity)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050868"(negative regulation of T cell activation)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020405|interpro:IPR020422|interpro:IPR029021|mint:Q9D7X3|reactome:R-MMU-202670|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)	-	-	comment:mint|function:This protein shows activity both toward tyrosine-protein phosphate as well as with serine-protein phosphate	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:CPkFDe9SCv4Nq8Dwl5NRteIKckg10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q99KV1	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-8328260|uniprotkb:Q8VHB1|uniprotkb:Q8VCY1|intact:MINT-1847287|uniprotkb:A6X957|uniprotkb:Q543I7|uniprotkb:Q8BK79|ensembl:ENSMUSP00000004574|ensembl:ENSMUSP00000126828|ensembl:ENSMUSP00000137542	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:djb11_mouse(display_long)|uniprotkb:Dnajb11(gene name)|psi-mi:Dnajb11(display_short)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_080676.3|refseq:NP_001177733.1|refseq:NP_001177734.1|dip:DIP-60531N|ensembl:ENSMUSG00000004460(gene)|ensembl:ENSMUST00000004574(transcript)|ensembl:ENSMUST00000166487(transcript)|ensembl:ENSMUST00000178320(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016556"(mRNA modification)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q99KV1	-	-	comment:mint	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:AwepE58LUoN43LmBMkof6jEPNCA10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9WUP7	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-8820873|ensembl:ENSMUSP00000140106|uniprotkb:Q9CVJ4|uniprotkb:Q9CXZ3|uniprotkb:Q9R107	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:uchl5_mouse(display_long)|uniprotkb:Uchl5(gene name)|psi-mi:Uchl5(display_short)|uniprotkb:Uch37(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSMUSG00000018189(gene)|ensembl:ENSMUST00000189936(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|rcsb pdb:4WLQ|rcsb pdb:4WLR|reactome:R-MMU-5689603|mint:Q9WUP7|refseq:NP_001153338.1|refseq:NP_062508.2	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:beQW0dMxUbBMmUuqIkLPRvRVNH410090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q05512	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-771728|uniprotkb:Q3T9L3|uniprotkb:Q6PDR4|uniprotkb:Q8BR95	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:mark2_mouse(display_long)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:Mark2(gene name)|psi-mi:Mark2(display_short)|uniprotkb:Emk(gene name synonym)|uniprotkb:PAR1 homolog(gene name synonym)|uniprotkb:PAR1 homolog b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001073857.1|refseq:NP_001073858.1|refseq:NP_001073859.1|refseq:NP_031954.2|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028375|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001764"(neuron migration)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008289"(lipid binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030425"(dendrite)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045180"(basal cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097427"(microtubule bundle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904526"(regulation of microtubule binding)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:RiipGX3uA3cvQACWclxzpLcJQVU10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9ERD7	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2255594|uniprotkb:Q3UF42|uniprotkb:Q5I036|ensembl:ENSMUSP00000071134	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:tbb3_mouse(display_long)|uniprotkb:Tubb3(gene name)|psi-mi:Tubb3(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_075768.1|dip:DIP-48419N|ensembl:ENSMUSG00000062380(gene)|ensembl:ENSMUST00000071134(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9ERD7|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:KhUQ3YFdcJvjwoHGykl7dv90vX810090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P03995	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1634365|uniprotkb:Q80VX6|uniprotkb:Q925K2|uniprotkb:Q925K3|uniprotkb:A1E2H7|uniprotkb:A2AH87|uniprotkb:Q09J71|uniprotkb:Q3USS4|uniprotkb:Q496R4|uniprotkb:Q496S3|uniprotkb:Q7TQ30|ensembl:ENSMUSP00000064691|uniprotkb:B2RTI7	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:gfap_mouse(display_long)|uniprotkb:Gfap(gene name)|psi-mi:Gfap(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001124492.1|refseq:NP_034407.2|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|ensembl:ENSMUSG00000020932(gene)|ensembl:ENSMUST00000067444(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0044297"(cell body)|go:"GO:0045103"(intermediate filament-based process)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097386"(glial cell projection)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|dip:DIP-1084N|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P03995	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:y7+aINs6vTxOHokkQCqgejlZfh010090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q8R570	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11573117|uniprotkb:Q3UNK4|uniprotkb:Q8BK87|ensembl:ENSMUSP00000010038	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:snp47_mouse(display_long)|uniprotkb:Synaptosomal-associated 47 kDa protein(gene name synonym)|uniprotkb:Snap47(gene name)|psi-mi:Snap47(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_653104.1|refseq:XP_006534084.1|refseq:XP_006534085.1|refseq:XP_006534086.1|refseq:XP_006534087.1|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR011993(Pleckstrin homology-type)|ensembl:ENSMUSG00000009894(gene)|ensembl:ENSMUST00000010038(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:wqRTlsj5F7kMg80mENjwhqw6FlU10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q02053	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2310520|uniprotkb:A6H6S6|uniprotkb:P31253|uniprotkb:Q542H8|ensembl:ENSMUSP00000001989|ensembl:ENSMUSP00000086626	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:uba1_mouse(display_long)|uniprotkb:Uba1(gene name)|psi-mi:Uba1(display_short)|uniprotkb:Sbx(gene name synonym)|uniprotkb:Ube1(gene name synonym)|uniprotkb:Ube1ax(gene name synonym)|uniprotkb:Ube1x(gene name synonym)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Ubiquitin-like modifier-activating enzyme 1 X(gene name synonym)|uniprotkb:Ubiquitin-activating enzyme E1 X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001129557.1|refseq:NP_001263245.1|refseq:NP_001263246.1|refseq:NP_033483.2|ensembl:ENSMUSG00000001924(gene)|ensembl:ENSMUST00000001989(transcript)|ensembl:ENSMUST00000089217(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030057"(desmosome)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0032446"(protein modification by small protein conjugation)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:Q02053|rcsb pdb:1Z7L|rcsb pdb:2LZJ|rcsb pdb:2V31|reactome:R-MMU-8866652|reactome:R-MMU-983168|interpro:IPR019572	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:358Lm1CC2dWXeDL+IXAM2KaOlqM10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:O89058	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11573062	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:o89058_mouse(display_long)|uniprotkb:Impdh2(gene name)|psi-mi:Impdh2(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|go:"GO:0016491"(oxidoreductase activity)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:KqX5kBYmRN0sR4fL0WHMD2j6u8g10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q61768	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-776129|uniprotkb:Q5BL10|uniprotkb:O08711|uniprotkb:Q61580|ensembl:ENSMUSP00000025083	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:kinh_mouse(display_long)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)|uniprotkb:Kif5b(gene name)|psi-mi:Kif5b(display_short)|uniprotkb:Khcs(gene name synonym)|uniprotkb:Kns1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_032474.2|dip:DIP-32053N|ensembl:ENSMUSG00000006740(gene)|ensembl:ENSMUST00000025083(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0021766"(hippocampus development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q61768|rcsb pdb:6IGN|rcsb pdb:6IGV|reactome:R-MMU-2132295|reactome:R-MMU-5625970|reactome:R-MMU-6811434|reactome:R-MMU-983189	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:11aePhwWZOqqAabjyanVgdHQQso10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q61177	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1216438	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:q61177_mouse(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:WjL03qwk8iDJOV9w6r6n4vazPis10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9R0Y5	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-777466|uniprotkb:A2AK80|uniprotkb:Q542C5|uniprotkb:Q9R0Y4|ensembl:ENSMUSP00000108902|ensembl:ENSMUSP00000108903	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:kad1_mouse(display_long)|uniprotkb:ATP-AMP transphosphorylase 1(gene name synonym)|uniprotkb:Myokinase(gene name synonym)|uniprotkb:Ak1(gene name)|psi-mi:Ak1(display_short)|uniprotkb:"ATP:AMP phosphotransferase"(gene name synonym)|uniprotkb:Adenylate monophosphate kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001185719.1|refseq:NP_001185720.1|refseq:NP_001185721.1|refseq:NP_067490.1|refseq:XP_006497687.1|ensembl:ENSMUSG00000026817(gene)|ensembl:ENSMUST00000113277(transcript)|ensembl:ENSMUST00000113278(transcript)|go:"GO:0001520"(outer dense fiber)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0030017"(sarcomere)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043005"(neuron projection)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046103"(inosine biosynthetic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006267(Adenylate kinase, isozyme 1)|interpro:IPR027417|interpro:IPR028582|interpro:IPR033690|mint:Q9R0Y5|reactome:R-MMU-499943	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:HTydMeIFNEaVZDs7sEN7aLieuVg10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9QZB1	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11573082|uniprotkb:Q9CUV8|uniprotkb:Q9QZB2|uniprotkb:Q3TY63|uniprotkb:Q14A97|ensembl:ENSMUSP00000002533	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:rgs20_mouse(display_long)|uniprotkb:Regulator of G-protein signaling Z1(gene name synonym)|uniprotkb:Rgsz1(gene name synonym)|uniprotkb:Rgs20(gene name)|psi-mi:Rgs20(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001277301.1|refseq:NP_067349.2|refseq:XP_011236702.1|ensembl:ENSMUSG00000002459(gene)|ensembl:ENSMUST00000002533(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016020"(membrane)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR036305|reactome:R-MMU-418594|reactome:R-MMU-418597	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:RxpGDWuzGbGro6QR1hSLUmIQl1M10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q7TSN6	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11573110|uniprotkb:Q80UD8|uniprotkb:Q8BX88|uniprotkb:Q0VBS2|ensembl:ENSMUSP00000058887	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:gp151_mouse(display_long)|uniprotkb:GPCR-2037(gene name synonym)|uniprotkb:Pgr7(gene name synonym)|uniprotkb:G-protein coupled receptor PGR7(gene name synonym)|uniprotkb:Gpr151(gene name)|psi-mi:Gpr151(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_853521.1|ensembl:ENSMUSG00000042816(gene)|ensembl:ENSMUST00000054738(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010447"(response to acidic pH)|go:"GO:0042802"(identical protein binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:fDb7Cr/pD+XWxHt3H5sPKlr6Yqk10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P68369	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P38647	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q64302	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11573099|uniprotkb:Q3TP49|ensembl:ENSMUSP00000029376|ensembl:ENSMUSP00000130999|ensembl:ENSMUSP00000143652	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:t4s1_mouse(display_long)|uniprotkb:M3s1(gene name synonym)|uniprotkb:Membrane component chromosome 3 surface marker 1 homolog(gene name synonym)|uniprotkb:Tumor-associated antigen L6(gene name synonym)|uniprotkb:Tm4sf1(gene name)|psi-mi:Tm4sf1(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_032562.1|refseq:XP_006501143.1|ensembl:ENSMUSG00000027800(gene)|ensembl:ENSMUST00000029376(transcript)|ensembl:ENSMUST00000171384(transcript)|ensembl:ENSMUST00000196979(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008661(L6 membrane)|mint:Q64302	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:aJlYmpFY6wLdlqqmerFp3V4kR4E10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P97427	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-773110|uniprotkb:O08554|uniprotkb:O35097|ensembl:ENSMUSP00000031004	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:dpyl1_mouse(display_long)|uniprotkb:Collapsin response mediator protein 1(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 3(gene name synonym)|uniprotkb:Crmp1(gene name)|psi-mi:Crmp1(display_short)|uniprotkb:Dpysl1(gene name synonym)|uniprotkb:Ulip3(gene name synonym)|uniprotkb:Inactive dihydropyrimidinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_031791.3|ensembl:ENSMUSG00000029121(gene)|ensembl:ENSMUST00000031004(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007411"(axon guidance)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031005"(filamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1904530"(negative regulation of actin filament binding)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030624|interpro:IPR032466|mint:P97427|rcsb pdb:1KCX|reactome:R-MMU-399956	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:/fpPxm3SNtnLKjXWrWOuG0QO3Nk10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9CWE0	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11573071|uniprotkb:Q8BTP7|uniprotkb:Q3UJK3|ensembl:ENSMUSP00000099609|ensembl:ENSMUSP00000111983	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:mfr1l_mouse(display_long)|uniprotkb:Fam54b(gene name synonym)|uniprotkb:Mtfr1l(gene name)|psi-mi:Mtfr1l(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001243041.1|refseq:NP_084035.1|refseq:XP_006539319.1|refseq:XP_006539320.1|refseq:XP_006539321.1|ensembl:ENSMUSG00000046671(gene)|ensembl:ENSMUST00000102550(transcript)|ensembl:ENSMUST00000116279(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0009060"(aerobic respiration)|interpro:IPR007972(Protein of unknown function DUF729)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:90UvllQuVVlBEImCkCYRDTiUycU10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q8VED4	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11573106	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:q8ved4_mouse(display_long)|uniprotkb:Ppp2cb(gene name)|psi-mi:Ppp2cb(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|go:"GO:0106306"|go:"GO:0106307"	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:fZfbboNz4ugxrdL1XezkFsyw17E10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P18760	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1183994|ensembl:ENSMUSP00000147514	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:cof1_mouse(display_long)|uniprotkb:Cfl1(gene name)|psi-mi:Cfl1(display_short)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_031713.1|ensembl:ENSMUSG00000056201(gene)|ensembl:ENSMUST00000209469(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001842"(neural fold formation)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030175"(filopodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051511"(negative regulation of unidimensional cell growth)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090732"(cofilin-actin rod)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|go:"GO:1905873"(positive regulation of protein localization to cell leading edge)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|go:"GO:2000814"(positive regulation of barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P18760|dip:DIP-38073N	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:nw/9u2+2nq9Ef43SapV43MeOtjE10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9R0P9	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1635245|uniprotkb:Q9R122|ensembl:ENSMUSP00000031131	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:uchl1_mouse(display_long)|uniprotkb:Uchl1(gene name)|psi-mi:Uchl1(display_short)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_035800.2|ensembl:ENSMUSG00000029223(gene)|ensembl:ENSMUST00000031131(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007409"(axonogenesis)|go:"GO:0007412"(axon target recognition)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030424"(axon)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0035690"|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0050905"(neuromuscular process)|go:"GO:0055001"(muscle cell development)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR030297|interpro:IPR036959|interpro:IPR038765|mint:Q9R0P9|reactome:R-MMU-5689603|go:"GO:0019233"(sensory perception of pain)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:OwNZHaBcqFPb5UKgm9WtL6AXn/o10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9JL90	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11576443	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:q9jl90_mouse(display_long)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035629|go:"GO:0003779"(actin binding)|interpro:IPR036028	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:LhehUdXs0rAEY3dydjBBiTccDnU10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9D6F9	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-911077|uniprotkb:Q62364|uniprotkb:Q80Y54|ensembl:ENSMUSP00000071135	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:tbb4a_mouse(display_long)|uniprotkb:Tubb4a(gene name)|psi-mi:Tubb4a(display_short)|uniprotkb:Tubb4(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_033477.2|ensembl:ENSMUSG00000062591(gene)|ensembl:ENSMUST00000071135(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0030030"(cell projection organization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0033269"(internode region of axon)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR037103|mint:Q9D6F9|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|interpro:IPR036525	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:mMveBNZkQs2x0dyHm/ghVWBe4/410090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P05213	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:A0A0B4J1F4	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11576447|uniprotkb:Q8VD69|ensembl:ENSMUSP00000044578	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:arrd4_mouse(display_long)|uniprotkb:Arrdc4(gene name)|psi-mi:Arrdc4(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001036057.1|refseq:NP_079825.2|ensembl:ENSMUSG00000042659(gene)|ensembl:ENSMUST00000048068(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0140112"(extracellular vesicle biogenesis)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:FsyKxF31/PmEqJ3Qtp/dJbWjIOs10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:O88343	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-771342|uniprotkb:Q3USE4|uniprotkb:Q8BUG0|uniprotkb:Q8QZR9|uniprotkb:Q9R1C4|ensembl:ENSMUSP00000119325	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:s4a4_mouse(display_long)|uniprotkb:"Na(+)/HCO3(-) cotransporter"(gene name synonym)|uniprotkb:Solute carrier family 4 member 4(gene name synonym)|uniprotkb:Slc4a4(gene name)|psi-mi:Slc4a4(display_short)|uniprotkb:Nbc1(gene name synonym)|uniprotkb:Nbce1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001129732.1|refseq:NP_061230.2|ensembl:ENSMUSG00000060961(gene)|ensembl:ENSMUST00000148750(transcript)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0008510"("sodium:bicarbonate symporter activity")|go:"GO:0009986"(cell surface)|go:"GO:0015293"(symporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR003024(Sodium bicarbonate cotransporter)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|mint:O88343|reactome:R-MMU-425381	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:gZhNv38fjd32y3e6d63+ixWY5g810090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q61483	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-297125|ensembl:ENSMUSP00000014917|uniprotkb:Q6PFV7	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:dll1_mouse(display_long)|uniprotkb:Dll1(gene name)|psi-mi:Dll1(display_short)|uniprotkb:Drosophila Delta homolog 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	go:"GO:0014002"(astrocyte development)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021510"(spinal cord development)|go:"GO:0021688"(cerebellar molecular layer formation)|go:"GO:0021693"(cerebellar Purkinje cell layer structural organization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0035265"(organ growth)|go:"GO:0040008"(regulation of growth)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0045121"(membrane raft)|go:"GO:0045596"(negative regulation of cell differentiation)|ensembl:ENSMUSG00000014773(gene)|ensembl:ENSMUST00000014917(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0001947"(heart looping)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007399"(nervous system development)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|reactome:R-MMU-9013507|go:"GO:0045608"(negative regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048630"(skeletal muscle tissue growth)|go:"GO:0048631"(regulation of skeletal muscle tissue growth)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0048665"(neuron fate specification)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0060853"(Notch signaling pathway involved in arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0072006"(nephron development)|go:"GO:0072014"(proximal tubule development)|go:"GO:0072070"(loop of Henle development)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097009"(energy homeostasis)|go:"GO:0097102"(endothelial tip cell fate specification)|go:"GO:0048839"(inner ear development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098773"(skin epidermis development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:1900746"(regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|refseq:NP_031891.2|dip:DIP-32600N	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:XF72rbPhGwtIVtvryYqH8opo5Fc10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9Z0H8	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-775282|uniprotkb:Q7TSI9|uniprotkb:Q8CHU1|uniprotkb:Q9EP81|ensembl:ENSMUSP00000098212	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:clip2_mouse(display_long)|uniprotkb:Cytoplasmic linker protein 2(gene name synonym)|uniprotkb:Cytoplasmic linker protein 115(gene name synonym)|uniprotkb:Clip2(gene name)|psi-mi:Clip2(display_short)|uniprotkb:Kiaa0291(gene name synonym)|uniprotkb:Cyln2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001034251.1|refseq:NP_034120.2|ensembl:ENSMUSG00000063146(gene)|ensembl:ENSMUST00000100647(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042599"(lamellar body)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1901588"(dendritic microtubule)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR028394|interpro:IPR036859|mint:Q9Z0H8	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:XOvAwO1BpspbwnEPfothhJzQ7ns10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q80TV8	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-908322|uniprotkb:Q505G6|uniprotkb:Q6DI75|uniprotkb:Q6PG14|uniprotkb:Q8BNS4|uniprotkb:Q99JH5|uniprotkb:Q99JI2|uniprotkb:Q9CVU1	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:clap1_mouse(display_long)|uniprotkb:Clasp1(gene name)|psi-mi:Clasp1(display_short)|uniprotkb:Cytoplasmic linker-associated protein 1(gene name synonym)|uniprotkb:Kiaa0622(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001280229.1|refseq:NP_001280230.1|refseq:NP_083985.2|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024395|interpro:IPR021133|interpro:IPR028399|interpro:IPR034085|mint:Q80TV8|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031111"(negative regulation of microtubule polymerization or depolymerization)|go:"GO:0031592"(centrosomal corona)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045180"(basal cortex)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|reactome:R-MMU-2500257	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:HwJCOu/w9CSWzqLB7WEjrC4a3bg10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q02956	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-642057|uniprotkb:A2AD76|ensembl:ENSMUSP00000030922|intact:EBI-11573047|uniprotkb:Q3UHM5|uniprotkb:Q7TST7	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:kpcz_mouse(display_long)|uniprotkb:nPKC-zeta(gene name synonym)|uniprotkb:Prkcz(gene name)|psi-mi:Prkcz(display_short)|uniprotkb:Pkcz(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_032886.2|ensembl:ENSMUSG00000029053(gene)|ensembl:ENSMUST00000030922(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001725"(stress fiber)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0016477"(cell migration)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045179"(apical cortex)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043203"(axon hillock)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990138"(neuron projection extension)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051899"(membrane depolarization)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012233(Protein kinase C, zeta/iota)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034877|mint:Q02956|reactome:R-MMU-2173791|reactome:R-MMU-5218921|reactome:R-MMU-5668599|reactome:R-MMU-9634635	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:MYpdSZCYytyavjkeOeTCG21yEYg10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P68368	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2642970|uniprotkb:Q3TY31|uniprotkb:P05215|ensembl:ENSMUSP00000140657	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:tba4a_mouse(display_long)|uniprotkb:Tuba4a(gene name)|psi-mi:Tuba4a(display_short)|uniprotkb:Tuba4(gene name synonym)|uniprotkb:Tubulin alpha-4 chain(gene name synonym)|uniprotkb:Alpha-tubulin 4(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_033473.1|ensembl:ENSMUSG00000026202(gene)|ensembl:ENSMUST00000186213(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68368|reactome:R-MMU-114608|reactome:R-MMU-190840|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|reactome:R-MMU-2132295	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P63017	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P68373	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-3647590|uniprotkb:P05216|uniprotkb:Q9CSE9|ensembl:ENSMUSP00000051033	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:tba1c_mouse(display_long)|uniprotkb:Tuba1c(gene name)|psi-mi:Tuba1c(display_short)|uniprotkb:Tuba6(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_033474.1|ensembl:ENSMUSG00000043091(gene)|ensembl:ENSMUST00000058914(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045121"(membrane raft)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68373|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|go:"GO:0005881"(cytoplasmic microtubule)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:/v0eESwae8IubY6sq0wcTeeXHaQ10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q91Z83	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-299920|ensembl:ENSMUSP00000099867|ensembl:ENSMUSP00000126840|uniprotkb:Q3TGM2|uniprotkb:Q3TZN2	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:myh7_mouse(display_long)|uniprotkb:Myh7(gene name)|psi-mi:Myh7(display_short)|uniprotkb:Myosin heavy chain 7(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle beta isoform(gene name synonym)|uniprotkb:Myosin heavy chain slow isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSMUSG00000053093(gene)|ensembl:ENSMUST00000102803(transcript)|ensembl:ENSMUST00000168485(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0014728"(regulation of the force of skeletal muscle contraction)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031449"(regulation of slow-twitch skeletal muscle fiber contraction)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q91Z83|refseq:NP_542766.1|refseq:XP_017171330.1|refseq:XP_017171331.1	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:bU/7TlAhyFe1cU0W5ljnnrelgMs10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P60879	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q8CI94	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-773709|uniprotkb:Q8K283|ensembl:ENSMUSP00000035743	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:pygb_mouse(display_long)|uniprotkb:Pygb(gene name)|psi-mi:Pygb(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_722476.1|ensembl:ENSMUSG00000033059(gene)|ensembl:ENSMUST00000045441(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q8CI94|reactome:R-MMU-6798695	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:sX820CE/XNwY/LEnJx/j4IF44Lk10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P39053	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-397785|ensembl:ENSMUSP00000122679|uniprotkb:A2AN50|uniprotkb:A2AN51|uniprotkb:A2AN54|uniprotkb:A2AN55|uniprotkb:Q3UNM1|uniprotkb:Q5DTN7|uniprotkb:Q61358|uniprotkb:Q61359|uniprotkb:Q61360|uniprotkb:Q6PDM5|uniprotkb:Q8JZZ4|uniprotkb:Q9CSY7|uniprotkb:Q9QXX1	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:dyn1_mouse(display_long)|uniprotkb:Dnm1(gene name)|psi-mi:Dnm1(display_short)|uniprotkb:Dnm(gene name synonym)|uniprotkb:Kiaa4093(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_034195.2|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR027741|interpro:IPR030381|mint:P39053|reactome:R-MMU-166016|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2132295|reactome:R-MMU-437239|reactome:R-MMU-8856828|ensembl:ENSMUSG00000026825(gene)|ensembl:ENSMUST00000139624(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043196"(varicosity)|go:"GO:0043209"(myelin sheath)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1901998"(toxin transport)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1904645"(response to amyloid-beta)|refseq:NP_001288666.1|refseq:XP_006497721.2|refseq:XP_006497722.2|refseq:XP_006497723.2|refseq:XP_006497724.2|refseq:XP_006497718.2|refseq:XP_017170817.1	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:wtPz3gwyxU6tAgh5091LQpt099I10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q7TQI3	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2309876|uniprotkb:Q3ULV9|uniprotkb:Q3V408|uniprotkb:Q8C326|uniprotkb:Q8R5F2|ensembl:ENSMUSP00000025679	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:otub1_mouse(display_long)|uniprotkb:Otub1(gene name)|psi-mi:Otub1(display_short)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_598911.1|ensembl:ENSMUSG00000024767(gene)|ensembl:ENSMUST00000025679(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q7TQI3|reactome:R-MMU-5689880|reactome:R-MMU-5689896	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:8wyAgdbYnbsj8QYkhuruP2tdw5Q10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q768S4	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11573051|uniprotkb:Q9D353|ensembl:ENSMUSP00000064202|ensembl:ENSMUSP00000113869	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:rph3l_mouse(display_long)|uniprotkb:Gm1753(gene name synonym)|uniprotkb:No C2 domains protein(gene name synonym)|uniprotkb:Noc2(gene name synonym)|uniprotkb:Rabphilin-3A-like protein(gene name synonym)|uniprotkb:Rph3al(gene name)|psi-mi:Rph3al(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001278088.1|refseq:NP_083824.1|refseq:XP_006533700.1|refseq:XP_006533701.1|refseq:XP_006533702.1|refseq:XP_006533703.1|refseq:XP_006533704.1|refseq:XP_006533705.1|refseq:XP_011247403.1|refseq:XP_011247404.1|ensembl:ENSMUSG00000020847(gene)|ensembl:ENSMUST00000066504(transcript)|ensembl:ENSMUST00000121287(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0030141"(secretory granule)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|interpro:IPR010911(Rab-binding)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR030538|interpro:IPR041282|interpro:IPR041857|interpro:IPR043566	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:tM5oiXDjsUgvEUTF45YFYaV1lPw10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:O70255	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11573095	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:mpzl2_mouse(display_long)|uniprotkb:Epithelial V-like antigen 1(gene name synonym)|uniprotkb:Eva(gene name synonym)|uniprotkb:Eva1(gene name synonym)|uniprotkb:Mpzl2(gene name)|psi-mi:Mpzl2(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR000920(Myelin P0 protein)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029863|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR036179	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:P1X4aT4c/dDFn+tHiSxr6IF/Lj810090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P80316	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-772379|uniprotkb:Q3TIE0|uniprotkb:Q3U530|uniprotkb:Q3UCU4|uniprotkb:Q3UJK9|uniprotkb:Q3UWA9|uniprotkb:Q542K3|uniprotkb:Q6ZQJ1|ensembl:ENSMUSP00000022842	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:tcpe_mouse(display_long)|uniprotkb:CCT-epsilon(gene name synonym)|uniprotkb:Cct5(gene name)|psi-mi:Cct5(display_short)|uniprotkb:Ccte(gene name synonym)|uniprotkb:Kiaa0098(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_031663.1|refseq:NP_001334964.1|ensembl:ENSMUSG00000022234(gene)|ensembl:ENSMUST00000022842(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012718(T-complex protein 1, epsilon subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80316|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:UpEEjKLyd92Zl4VnOTTlziuwAGA10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P46735	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-400887|uniprotkb:P70244|uniprotkb:Q80VD8|ensembl:ENSMUSP00000040447	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:myo1b_mouse(display_long)|uniprotkb:Myo1b(gene name)|psi-mi:Myo1b(display_short)|uniprotkb:Myosin I alpha(gene name synonym)|uniprotkb:MIH-L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_034993.2|ensembl:ENSMUSG00000018417(gene)|ensembl:ENSMUST00000046390(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030175"(filopodium)|go:"GO:0031982"(vesicle)|go:"GO:0033572"(transferrin transport)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:P46735	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:GStJH3DUQORwMi1ow0mHcBAf4io10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9R0P5	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1184008|ensembl:ENSMUSP00000099461	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:dest_mouse(display_long)|uniprotkb:Dstn(gene name)|psi-mi:Dstn(display_short)|uniprotkb:Dsn(gene name synonym)|uniprotkb:Sid23(gene name synonym)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Sid 23(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_062745.1|ensembl:ENSMUSG00000015932(gene)|ensembl:ENSMUST00000103172(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|interpro:IPR029924|mint:Q9R0P5	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:hqPae8VWEKvGPITqHtrSs78yI4M10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:B5X0E4	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11576437|uniprotkb:W5QLL5|ensembl:ENSMUSP00000046177	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:abcb5_mouse(display_long)|uniprotkb:ABCB5 P-gp(gene name synonym)|uniprotkb:P-glycoprotein ABCB5(gene name synonym)|uniprotkb:Abcb5(gene name)|psi-mi:Abcb5(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_084237.1|ensembl:ENSMUSG00000072791(gene)|ensembl:ENSMUST00000035515(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|reactome:R-MMU-382556	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:RKISECcMcLNqXHys9ZFnCUo5XrI10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:O08553	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-446064|uniprotkb:Q6P5D0|ensembl:ENSMUSP00000022629	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:dpyl2_mouse(display_long)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)|uniprotkb:Crmp2(gene name synonym)|uniprotkb:Ulip2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_034085.2|ensembl:ENSMUSG00000022048(gene)|ensembl:ENSMUST00000022629(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:O08553|rcsb pdb:5UQC|reactome:R-MMU-399956|reactome:R-MMU-437239	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P14602	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-299023|ensembl:ENSMUSP00000005077	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:hspb1_mouse(display_long)|uniprotkb:Hspb1(gene name)|psi-mi:Hspb1(display_short)|uniprotkb:Hsp25(gene name synonym)|uniprotkb:Hsp27(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Heat shock 25 kDa protein(gene name synonym)|uniprotkb:Growth-related 25 kDa protein(gene name synonym)|uniprotkb:p25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSMUSG00000004951(gene)|ensembl:ENSMUST00000005077(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043292"(contractile fiber)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045202"(synapse)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P14602|reactome:R-MMU-4420097|reactome:R-MMU-450408|reactome:R-MMU-5687128|reactome:R-MMU-9009391|refseq:NP_038588.2	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:c79cDHl0WGQlEO7vGeDaZfr2oAE10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:O55017	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-770881|uniprotkb:Q60609|ensembl:ENSMUSP00000037416	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:cac1b_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 5(gene name synonym)|uniprotkb:Brain calcium channel III(gene name synonym)|uniprotkb:Cacna1b(gene name)|psi-mi:Cacna1b(display_short)|uniprotkb:Cach5(gene name synonym)|uniprotkb:Cacnl1a5(gene name synonym)|uniprotkb:Cchn1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001035993.1|ensembl:ENSMUSG00000004113(gene)|ensembl:ENSMUST00000041342(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043679"(axon terminus)|go:"GO:0048265"(response to pain)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005447(Voltage-dependent calcium channel, N-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR043203|mint:O55017|reactome:R-MMU-112308	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:yTkuOwWJbxQkfOPg/TA8cPvpH+Q10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q64332	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-775668|uniprotkb:Q6NZR0|uniprotkb:Q9QWV7|ensembl:ENSMUSP00000009538	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:syn2_mouse(display_long)|uniprotkb:Synapsin II(gene name synonym)|uniprotkb:Syn2(gene name)|psi-mi:Syn2(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001104485.1|refseq:NP_038709.1|ensembl:ENSMUSG00000009394(gene)|ensembl:ENSMUST00000009538(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099504"(synaptic vesicle cycle)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028712|mint:Q64332|reactome:R-MMU-181429|reactome:R-MMU-212676	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:Y/RYUSlblGo1/3HGeKJmfS5yX+M10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:O88544	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-646659|ensembl:ENSMUSP00000048416	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:csn4_mouse(display_long)|uniprotkb:JAB1-containing signalosome subunit 4(gene name synonym)|uniprotkb:Cops4(gene name)|psi-mi:Cops4(display_short)|uniprotkb:Csn4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_036131.1|ensembl:ENSMUSG00000035297(gene)|ensembl:ENSMUST00000045993(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406|mint:O88544|rcsb pdb:1UFM|reactome:R-MMU-5696394|reactome:R-MMU-6781823|reactome:R-MMU-8856825|reactome:R-MMU-8951664|reactome:R-MMU-9013422	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:oD7xaeBArd5bKxdEAWM/r+5KMb010090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9WU84	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11573066|uniprotkb:Q9CRJ9|ensembl:ENSMUSP00000035486	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:ccs_mouse(display_long)|uniprotkb:Ccsd(gene name synonym)|uniprotkb:Superoxide dismutase copper chaperone(gene name synonym)|uniprotkb:Ccs(gene name)|psi-mi:Ccs(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_058588.1|ensembl:ENSMUSG00000034108(gene)|ensembl:ENSMUST00000037246(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0019899"(enzyme binding)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR018152|interpro:IPR024134|interpro:IPR036163|interpro:IPR036423|mint:Q9WU84|reactome:R-MMU-3299685|dip:DIP-48692N	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:QOHBXTrPAST7wM1oj2wouOgbw8010090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9CQV8	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-771608|uniprotkb:O70455|uniprotkb:Q3TY33|uniprotkb:Q3UAN6|ensembl:ENSMUSP00000018470	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:1433b_mouse(display_long)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Ywhab(gene name)|psi-mi:Ywhab(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_061223.2|refseq:XP_006499972.1|reactome:R-MMU-111447|reactome:R-MMU-165159|reactome:R-MMU-166208|reactome:R-MMU-170968|reactome:R-MMU-2028269|reactome:R-MMU-392517|reactome:R-MMU-450385|reactome:R-MMU-450513|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5675221|reactome:R-MMU-75035|reactome:R-MMU-9614399|ensembl:ENSMUSG00000018326(gene)|ensembl:ENSMUST00000018470(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:4GNT|rcsb pdb:5F74|rcsb pdb:5WFU|rcsb pdb:5WFX	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:g94luGOxfq+Jbi0ztZ7gbAkp+2A10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P11531	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q8BTM9	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11568961|uniprotkb:Q920A2|uniprotkb:Q811P7|uniprotkb:Q91ZC8|uniprotkb:Q3TRL5|uniprotkb:Q3U3I4|uniprotkb:Q3TNQ1|uniprotkb:Q8BKV7|ensembl:ENSMUSP00000032811	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:grp4_mouse(display_long)|uniprotkb:Rasgrp4(gene name)|psi-mi:Rasgrp4(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001167626.1|refseq:NP_660131.2|ensembl:ENSMUSG00000030589(gene)|ensembl:ENSMUST00000032811(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR020454|interpro:IPR023578|interpro:IPR036964|go:"GO:0007264"(small GTPase mediated signal transduction)|reactome:R-MMU-5673001	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:0cy4fFrfKwXB0bKXI7SxJgfrTrc10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9CQI3	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11573056|uniprotkb:Q3UQX5|uniprotkb:Q9ERL8|ensembl:ENSMUSP00000078293|ensembl:ENSMUSP00000107448	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:gmfb_mouse(display_long)|uniprotkb:Gmfb(gene name)|psi-mi:Gmfb(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_071306.2|ensembl:ENSMUSG00000062014(gene)|ensembl:ENSMUST00000079314(transcript)|ensembl:ENSMUST00000111817(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008083"(growth factor activity)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0071846"(actin filament debranching)|go:"GO:0071933"(Arp2/3 complex binding)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR011171(Glia maturation factor beta)|interpro:IPR029006|rcsb pdb:1V6F	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:Le1f38gxgIEpzo8lJ2/xCBJ9BCA10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q8R5C5	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2933912|ensembl:ENSMUSP00000047326	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:acty_mouse(display_long)|uniprotkb:Actr1b(gene name)|psi-mi:Actr1b(display_short)|uniprotkb:Actin-related protein 1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576452|imex:IM-24624-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSMUSG00000037351(gene)|ensembl:ENSMUST00000043951(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:Q8R5C5|reactome:R-MMU-2132295|reactome:R-MMU-6798695|refseq:NP_666219.1	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:vmo1BmcMHMiq4JiunSca8zS8/+E10090	intact-crc:F47B4F32F226DABC|rigid:xRlTcNGMvF13XsOjV/OVn7I4GDc	false	his tag:n-n|sufficient binding region:289-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9D7X3	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-8320546|intact:MINT-4093702|ensembl:ENSMUSP00000003612|ensembl:ENSMUSP00000102790	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:dus3_mouse(display_long)|uniprotkb:Dusp3(gene name)|psi-mi:Dusp3(display_short)|uniprotkb:T-DSP11(gene name synonym)|uniprotkb:Vaccinia H1-related phosphatase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_082483.1|ensembl:ENSMUSG00000003518(gene)|ensembl:ENSMUST00000003612(transcript)|ensembl:ENSMUST00000107172(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001772"(immunological synapse)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033549"(MAP kinase phosphatase activity)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050868"(negative regulation of T cell activation)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020405|interpro:IPR020422|interpro:IPR029021|mint:Q9D7X3|reactome:R-MMU-202670|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)	-	-	comment:mint|function:This protein shows activity both toward tyrosine-protein phosphate as well as with serine-protein phosphate	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:CPkFDe9SCv4Nq8Dwl5NRteIKckg10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P70276	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-8338613|intact:MINT-4106271	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:p70276_mouse(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:sns(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR043203|interpro:IPR044564|interpro:IPR028809|interpro:IPR027359|mint:P70276|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0034765"(regulation of ion transmembrane transport)	-	-	comment:mint	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:9mSmbWYX2ILWH/okCX6BfTmFGTk10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:E9Q557	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-688046|ensembl:ENSMUSP00000115062	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	-	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q5SUA5	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-777663|ensembl:ENSMUSP00000003459|uniprotkb:Q8BJ17|uniprotkb:Q8BJ65|uniprotkb:Q8R019|uniprotkb:Q91ZI1|uniprotkb:Q8BIT8	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:myo1g_mouse(display_long)|uniprotkb:Myo1g(gene name)|psi-mi:Myo1g(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSMUSG00000020437(gene)|ensembl:ENSMUST00000003459(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_848534.2|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030175"(filopodium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031982"(vesicle)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0071976"(cell gliding)|go:"GO:0120117"(T cell meandering migration)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:Q5SUA5	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:mIzhibZW73U3Fz9pkzll2qGaTPs10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q5SXR6	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-2308526|ensembl:ENSMUSP00000050220	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:q5sxr6_mouse(display_long)|uniprotkb:Cltc(gene name)|psi-mi:Cltc(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSMUSG00000047126(gene)|ensembl:ENSMUST00000060766(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:zQkMlHHZuHQwJ3cU5pWAx/f6guc10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q6PIC6	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-769101|ensembl:ENSMUSP00000079691	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:at1a3_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-3(gene name synonym)|uniprotkb:"Na(+)/K(+) ATPase alpha(III) subunit"(gene name synonym)|uniprotkb:Atp1a3(gene name)|psi-mi:Atp1a3(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001277398.1|ensembl:ENSMUSG00000040907(gene)|ensembl:ENSMUST00000080882(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0016020"(membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030424"(axon)|go:"GO:0031090"(organelle membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|reactome:R-MMU-936837|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086037"("P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential")|go:"GO:0098794"(postsynapse)|go:"GO:0098984"(neuron to neuron synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099520"(ion antiporter activity involved in regulation of presynaptic membrane potential)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIC6|go:"GO:0045202"(synapse)|reactome:R-MMU-5578775	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:1sz4qkpfVGTvDfvmBVIE3wsH2Rs10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:O08553	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-446064|uniprotkb:Q6P5D0|ensembl:ENSMUSP00000022629	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:dpyl2_mouse(display_long)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)|uniprotkb:Crmp2(gene name synonym)|uniprotkb:Ulip2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_034085.2|ensembl:ENSMUSG00000022048(gene)|ensembl:ENSMUST00000022629(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:O08553|rcsb pdb:5UQC|reactome:R-MMU-399956|reactome:R-MMU-437239	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q02956	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-642057|uniprotkb:A2AD76|ensembl:ENSMUSP00000030922|intact:EBI-11573047|uniprotkb:Q3UHM5|uniprotkb:Q7TST7	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:kpcz_mouse(display_long)|uniprotkb:nPKC-zeta(gene name synonym)|uniprotkb:Prkcz(gene name)|psi-mi:Prkcz(display_short)|uniprotkb:Pkcz(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_032886.2|ensembl:ENSMUSG00000029053(gene)|ensembl:ENSMUST00000030922(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001725"(stress fiber)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0016477"(cell migration)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045179"(apical cortex)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043203"(axon hillock)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990138"(neuron projection extension)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051899"(membrane depolarization)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012233(Protein kinase C, zeta/iota)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034877|mint:Q02956|reactome:R-MMU-2173791|reactome:R-MMU-5218921|reactome:R-MMU-5668599|reactome:R-MMU-9634635	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:MYpdSZCYytyavjkeOeTCG21yEYg10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P99024	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-350896|uniprotkb:P05218|uniprotkb:Q3TFB6|uniprotkb:Q3THH9|uniprotkb:Q3TIL1|uniprotkb:Q3UAV4|uniprotkb:Q3UF52|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|uniprotkb:B1B178|ensembl:ENSMUSP00000001566	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:tbb5_mouse(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_035785.1|interpro:IPR023123|interpro:IPR036525|interpro:IPR018316|interpro:IPR037103|mint:P99024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518|ensembl:ENSMUSG00000001525(gene)|ensembl:ENSMUST00000001566(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P63328	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-397208|uniprotkb:P12816|uniprotkb:P20652|uniprotkb:Q3UCU1|uniprotkb:Q64135|ensembl:ENSMUSP00000053101	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:pp2ba_mouse(display_long)|uniprotkb:Ppp3ca(gene name)|psi-mi:Ppp3ca(display_short)|uniprotkb:Calna(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit alpha isoform(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_032939.1|refseq:NP_001280551.1|ensembl:ENSMUSG00000028161(gene)|ensembl:ENSMUST00000056758(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004723"(calcium-dependent protein serine/threonine phosphatase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0036057"(slit diaphragm)|go:"GO:0042383"(sarcolemma)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903244"(positive regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905205"(positive regulation of connective tissue replacement)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|mint:P63328|rcsb pdb:4ORB|reactome:R-MMU-2025928|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-5607763|dip:DIP-31543N	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:98yAyDGZZxKYOv22ejceyfJbvao10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q8BXH3	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11576527|ensembl:ENSMUSP00000022501	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:q8bxh3_mouse(display_long)|uniprotkb:Gucy1b2(gene name)|psi-mi:Gucy1b2(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_766398.1|ensembl:ENSMUSG00000021933(gene)|ensembl:ENSMUST00000022501(transcript)|go:"GO:0004383"(guanylate cyclase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0020037"(heme binding)|go:"GO:0043167"(ion binding)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR011644(Haem NO binding)|interpro:IPR011645(Haem NO binding associated)|interpro:IPR018297|interpro:IPR024096|interpro:IPR029787|interpro:IPR038158|interpro:IPR042463	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:FTOX93Q8k55IXVx6kpzvKzf7CFk10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q8BMG7	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11573203|uniprotkb:Q80TQ6|uniprotkb:Q6PEU0|uniprotkb:Q8BX72	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:rbgpr_mouse(display_long)|uniprotkb:Kiaa0839(gene name synonym)|uniprotkb:Rab3 GTPase-activating protein 150 kDa subunit(gene name synonym)|uniprotkb:Rab3-GAP p150(gene name synonym)|uniprotkb:Rab3-GAP regulatory subunit(gene name synonym)|uniprotkb:Rab3gap2(gene name)|psi-mi:Rab3gap2(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR026059|interpro:IPR029257|interpro:IPR032839|refseq:NP_001157226.1|reactome:R-MMU-6811436|reactome:R-MMU-8876198|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:1903061"(positive regulation of protein lipidation)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|go:"GO:2000786"(positive regulation of autophagosome assembly)	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:vhiyZrqe5G2loUXEkgqdWoGyKw410090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P68373	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-3647590|uniprotkb:P05216|uniprotkb:Q9CSE9|ensembl:ENSMUSP00000051033	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:tba1c_mouse(display_long)|uniprotkb:Tuba1c(gene name)|psi-mi:Tuba1c(display_short)|uniprotkb:Tuba6(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_033474.1|ensembl:ENSMUSG00000043091(gene)|ensembl:ENSMUST00000058914(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045121"(membrane raft)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68373|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|go:"GO:0005881"(cytoplasmic microtubule)	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:/v0eESwae8IubY6sq0wcTeeXHaQ10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:O54983	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-2308548|ensembl:ENSMUSP00000033198	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:crym_mouse(display_long)|uniprotkb:Crym(gene name)|psi-mi:Crym(display_short)|uniprotkb:NADP-regulated thyroid-hormone-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_057878.1|ensembl:ENSMUSG00000030905(gene)|ensembl:ENSMUST00000033198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0042403"(thyroid hormone metabolic process)|go:"GO:0042562"(hormone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0047127"(thiomorpholine-carboxylate dehydrogenase activity)|go:"GO:0050661"(NADP binding)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070327"(thyroid hormone transport)|interpro:IPR003462(Ornithine cyclodeaminase/mu-crystallin)|interpro:IPR023401|interpro:IPR036291|mint:O54983|rcsb pdb:4BV8|rcsb pdb:4BV9|rcsb pdb:4BVA|reactome:R-MMU-71064	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:mO0tQhAT08yqCV0Htw/2KLj1v0A10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P63318	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-397096|uniprotkb:P05697|ensembl:ENSMUSP00000097874	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:kpcg_mouse(display_long)|uniprotkb:Pkcc(gene name synonym)|uniprotkb:Pkcg(gene name synonym)|uniprotkb:Prkcc(gene name synonym)|uniprotkb:Prkcg(gene name)|psi-mi:Prkcg(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_035232.1|ensembl:ENSMUSG00000078816(gene)|ensembl:ENSMUST00000100301(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043278"(response to morphine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0044305"(calyx of Held)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048265"(response to pain)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:0005829"(cytosol)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|interpro:IPR020454|interpro:IPR035892|mint:P63318|reactome:R-MMU-111933|reactome:R-MMU-114516|reactome:R-MMU-416993|reactome:R-MMU-5099900|reactome:R-MMU-76005	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:t4ukCPPAnYUtHCH1hnQE+uiyfEM10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q8CI94	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-773709|uniprotkb:Q8K283|ensembl:ENSMUSP00000035743	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:pygb_mouse(display_long)|uniprotkb:Pygb(gene name)|psi-mi:Pygb(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_722476.1|ensembl:ENSMUSG00000033059(gene)|ensembl:ENSMUST00000045441(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q8CI94|reactome:R-MMU-6798695	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:sX820CE/XNwY/LEnJx/j4IF44Lk10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q8C9D4	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11576521|ensembl:ENSMUSP00000108468|ensembl:ENSMUSP00000127193	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:q8c9d4_mouse(display_long)|uniprotkb:JNK3A2(gene name synonym)|uniprotkb:Mapk10(gene name)|psi-mi:Mapk10(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001075036.1|ensembl:ENSMUSG00000046709(gene)|ensembl:ENSMUST00000112847(transcript)|ensembl:ENSMUST00000170792(transcript)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:oQC8/rfpCrG6lt7qbFs2esNrxSA10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9ERD7	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-2255594|uniprotkb:Q3UF42|uniprotkb:Q5I036|ensembl:ENSMUSP00000071134	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:tbb3_mouse(display_long)|uniprotkb:Tubb3(gene name)|psi-mi:Tubb3(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_075768.1|dip:DIP-48419N|ensembl:ENSMUSG00000062380(gene)|ensembl:ENSMUST00000071134(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9ERD7|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:KhUQ3YFdcJvjwoHGykl7dv90vX810090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P18760	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1183994|ensembl:ENSMUSP00000147514	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:cof1_mouse(display_long)|uniprotkb:Cfl1(gene name)|psi-mi:Cfl1(display_short)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_031713.1|ensembl:ENSMUSG00000056201(gene)|ensembl:ENSMUST00000209469(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001842"(neural fold formation)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030175"(filopodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051511"(negative regulation of unidimensional cell growth)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090732"(cofilin-actin rod)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|go:"GO:1905873"(positive regulation of protein localization to cell leading edge)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|go:"GO:2000814"(positive regulation of barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P18760|dip:DIP-38073N	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:nw/9u2+2nq9Ef43SapV43MeOtjE10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9JHJ5	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11295219|ensembl:ENSMUSP00000008734	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:5ht3b_mouse(display_long)|uniprotkb:Htr3b(gene name)|psi-mi:Htr3b(display_short)|uniprotkb:Serotonin receptor 3B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_064670.1|ensembl:ENSMUSG00000008590(gene)|ensembl:ENSMUST00000008734(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009986"(cell surface)|go:"GO:0022850"(serotonin-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|interpro:IPR008132(5-hydroxytryptamine 3 receptor)|interpro:IPR008134(5-hydroxytryptamine 3 receptor, B subunit)|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-112314|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:1904602"(serotonin-activated cation-selective channel complex)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:bXJ8MphyuGnmc2kr6FbP7S9tCUE10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q61699	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-772450|uniprotkb:Q3TNS2|uniprotkb:Q3UIY8|uniprotkb:Q62578|uniprotkb:Q62579|uniprotkb:Q6A0A5|uniprotkb:Q8C430|uniprotkb:Q8VCW6|ensembl:ENSMUSP00000144413|ensembl:ENSMUSP00000144654	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:hs105_mouse(display_long)|uniprotkb:Heat shock-related 100 kDa protein E7I(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:42 degrees C-HSP(gene name synonym)|uniprotkb:Hsph1(gene name)|psi-mi:Hsph1(display_short)|uniprotkb:Hsp105(gene name synonym)|uniprotkb:Hsp110(gene name synonym)|uniprotkb:Kiaa0201(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_038587.2|refseq:NP_001334463.1|dip:DIP-32354N|ensembl:ENSMUSG00000029657(gene)|ensembl:ENSMUST00000201452(transcript)|ensembl:ENSMUST00000202361(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q61699|reactome:R-MMU-3371453	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:pZByRgd8f5XdmB138rYxEMrwkRY10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q5BJ29	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11573196|uniprotkb:Q6ZQ36|ensembl:ENSMUSP00000061305	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:fbxl7_mouse(display_long)|uniprotkb:F-box and leucine-rich repeat protein 7(gene name synonym)|uniprotkb:Kiaa0840(gene name synonym)|uniprotkb:Fbxl7(gene name)|psi-mi:Fbxl7(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_795933.2|ensembl:ENSMUSG00000043556(gene)|ensembl:ENSMUST00000059204(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0051301"(cell division)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8854050|reactome:R-MMU-8951664|reactome:R-MMU-983168|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:CRCutZpHgBKdlNSZx9PEpX7YKFc10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q8CGD9	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11576531	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:q8cgd9_mouse(display_long)|uniprotkb:Atp1a3(gene name)|psi-mi:Atp1a3(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR023298|interpro:IPR023214|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:vABv7aLcONkcUuEz69koaLRB3v810090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9CQI3	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11573056|uniprotkb:Q3UQX5|uniprotkb:Q9ERL8|ensembl:ENSMUSP00000078293|ensembl:ENSMUSP00000107448	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:gmfb_mouse(display_long)|uniprotkb:Gmfb(gene name)|psi-mi:Gmfb(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_071306.2|ensembl:ENSMUSG00000062014(gene)|ensembl:ENSMUST00000079314(transcript)|ensembl:ENSMUST00000111817(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008083"(growth factor activity)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0071846"(actin filament debranching)|go:"GO:0071933"(Arp2/3 complex binding)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR011171(Glia maturation factor beta)|interpro:IPR029006|rcsb pdb:1V6F	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:Le1f38gxgIEpzo8lJ2/xCBJ9BCA10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9D6F9	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-911077|uniprotkb:Q62364|uniprotkb:Q80Y54|ensembl:ENSMUSP00000071135	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:tbb4a_mouse(display_long)|uniprotkb:Tubb4a(gene name)|psi-mi:Tubb4a(display_short)|uniprotkb:Tubb4(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_033477.2|ensembl:ENSMUSG00000062591(gene)|ensembl:ENSMUST00000071135(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0030030"(cell projection organization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0033269"(internode region of axon)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR037103|mint:Q9D6F9|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|interpro:IPR036525	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:mMveBNZkQs2x0dyHm/ghVWBe4/410090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:A2A863	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-9630531|uniprotkb:A2A865|uniprotkb:A2A866|uniprotkb:Q6PCS0|uniprotkb:Q8R3J1|uniprotkb:Q91W15|ensembl:ENSMUSP00000102066|ensembl:ENSMUSP00000102069	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:itb4_mouse(display_long)|uniprotkb:Itgb4(gene name)|psi-mi:Itgb4(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:XP_006532635.1|refseq:XP_006532636.1|refseq:XP_006532637.1|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|reactome:R-MMU-3000157|reactome:R-MMU-3000170|reactome:R-MMU-446107|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|ensembl:ENSMUSG00000020758(gene)|ensembl:ENSMUST00000106458(transcript)|ensembl:ENSMUST00000106461(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0038132"(neuregulin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:L62yPZPfhU3Z/HQ4GfCawekWt9810090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q61177	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1216438	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:q61177_mouse(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:WjL03qwk8iDJOV9w6r6n4vazPis10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P38647	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P30999	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-529924|uniprotkb:Q3TSU9|uniprotkb:Q80XQ4|uniprotkb:Q8CHF8|ensembl:ENSMUSP00000064518|ensembl:ENSMUSP00000107320|ensembl:ENSMUSP00000141166	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ctnd1_mouse(display_long)|uniprotkb:Kiaa0384(gene name synonym)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:Ctnnd1(gene name)|psi-mi:Ctnnd1(display_short)|uniprotkb:Catns(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001078917.1|refseq:NP_001078918.1|refseq:NP_001078919.1|refseq:NP_001078922.1|refseq:NP_031641.2|refseq:XP_006498698.1|refseq:XP_017170690.1|refseq:XP_017170697.1|dip:DIP-31972N|ensembl:ENSMUSG00000034101(gene)|ensembl:ENSMUSG00000101645(gene)|ensembl:ENSMUST00000067232(transcript)|ensembl:ENSMUST00000111691(transcript)|ensembl:ENSMUST00000189772(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001822"(kidney development)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060690"(epithelial cell differentiation involved in salivary gland development)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:P30999|reactome:R-MMU-418990|reactome:R-MMU-5218920	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:CvcAbgejB5iLlsSAxt47G/6W3P410090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P70336	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-771800|uniprotkb:Q8BR64|uniprotkb:Q8CBR0|uniprotkb:A5XDA7	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:rock2_mouse(display_long)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase 2(gene name synonym)|uniprotkb:p164 ROCK-2(gene name synonym)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase II(gene name synonym)|uniprotkb:Rock2(gene name)|psi-mi:Rock2(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_033098.2|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020684|interpro:IPR015008(Rho Binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011072(HR1 rho-binding repeat)|mint:P70336|interpro:IPR037311|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002931"(response to ischemia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0031644"(regulation of nervous system process)|go:"GO:0032723"(positive regulation of connective tissue growth factor production)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0072518"(Rho-dependent protein serine/threonine kinase activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090271"(positive regulation of fibroblast growth factor production)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110061"(regulation of angiotensin-activated signaling pathway)|go:"GO:0150033"(negative regulation of protein localization to lysosome)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:1905205"(positive regulation of connective tissue replacement)|go:"GO:1990776"(response to angiotensin)|reactome:R-MMU-3928662|reactome:R-MMU-416482|reactome:R-MMU-416572|reactome:R-MMU-4420097|reactome:R-MMU-5627117|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013407|reactome:R-MMU-9013422	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:XGh4GUDWts/RI6osd4zKXeh0lAE10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q64512	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-4284057|uniprotkb:Q61494|uniprotkb:Q62135|uniprotkb:Q64499	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ptn13_mouse(display_long)|uniprotkb:Ptpn13(gene name)|psi-mi:Ptpn13(display_short)|uniprotkb:Ptp14(gene name synonym)|uniprotkb:PTP36(gene name synonym)|uniprotkb:Protein tyrosine phosphatase DPZPTP(gene name synonym)|uniprotkb:Protein tyrosine phosphatase PTP-BL(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase RIP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR035963|interpro:IPR036034|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|rcsb pdb:6GBD|rcsb pdb:6GBE|refseq:NP_035334.2|interpro:IPR019749|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR018980|interpro:IPR011019(KIND)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|rcsb pdb:1GM1|rcsb pdb:1OZI|rcsb pdb:1VJ6|interpro:IPR029021|interpro:IPR029071|go:"GO:0001650"(fibrillar center)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0030496"(midbody)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|reactome:R-MMU-1660499|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:cPfYanrHD/RnZ+Akt306Ua1CQxI10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:G3X907	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11573215|ensembl:ENSMUSP00000033965	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:g3x907_mouse(display_long)|uniprotkb:Odz3(gene name synonym)|uniprotkb:Tenm3(gene name)|psi-mi:Tenm3(display_short)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_035987.3|refseq:XP_006509469.1|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048666"(neuron development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR006530(YD repeat)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR009471(Teneurin intracellular, N-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR022385|interpro:IPR027691|interpro:IPR028916|ensembl:ENSMUSG00000031561(gene)|ensembl:ENSMUST00000033965(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042995"(cell projection)	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:d0s+xvsor0KNYsXoeU0m8ICTchA10090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P20357	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-397863|ensembl:ENSMUSP00000109646|uniprotkb:E9QLE1	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:mtap2_mouse(display_long)|uniprotkb:Map2(gene name)|psi-mi:Map2(display_short)|uniprotkb:Mtap2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576525|imex:IM-24624-76	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSMUSG00000015222(gene)|ensembl:ENSMUST00000114013(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005519"(cytoskeletal regulatory protein binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016358"(dendrite development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043203"(axon hillock)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044297"(cell body)|go:"GO:0044307"(dendritic branch)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097442"(CA3 pyramidal cell dendrite)|go:"GO:0150001"(primary dendrite)|go:"GO:0150002"(distal dendrite)|go:"GO:0150014"(apical distal dendrite)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1903744"(positive regulation of anterograde synaptic vesicle transport)|go:"GO:1903827"|go:"GO:1904527"(negative regulation of microtubule binding)|go:"GO:1990635"(proximal dendrite)|go:"GO:1990769"(proximal neuron projection)|go:"GO:2000575"(obsolete negative regulation of microtubule motor activity)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR013588(MAP2/Tau projection)|interpro:IPR030797|mint:P20357|refseq:XP_006495817.1|refseq:NP_001297563.1	-	-	-	figure legend:"Supplementary Table 1 (suite 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/22	2019/01/23	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:iZ9zGAAalOtaFcgpzAQ80o+lCj010090	intact-crc:B1F5955B85FEF879|rigid:4/IF7bO1qoRvlAxSfUtwIsFq45o	false	his tag:n-n|sufficient binding region:304-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P62834	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-491414|uniprotkb:P10113|ensembl:ENSP00000348786|ensembl:ENSP00000358723|intact:EBI-1047696	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:rap1a_human(display_long)|uniprotkb:GTP-binding protein smg p21A(gene name synonym)|uniprotkb:Ras-related protein Krev-1(gene name synonym)|uniprotkb:C21KG(gene name synonym)|uniprotkb:G-22K(gene name synonym)|uniprotkb:RAP1A(gene name)|psi-mi:RAP1A(display_short)|uniprotkb:KREV1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	go:"GO:0097421"(liver regeneration)|refseq:NP_001278825.1|refseq:NP_001010935.1|refseq:NP_002875.1|go:"GO:0035579"(specific granule membrane)|go:"GO:0035690"|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097327"(response to antineoplastic agent)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|ensembl:ENSG00000116473(gene)|ensembl:ENST00000356415(transcript)|ensembl:ENST00000369709(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010008"(endosome membrane)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0030054"(cell junction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR038851|rcsb pdb:1C1Y|rcsb pdb:1GUA|rcsb pdb:3KUC|rcsb pdb:4KVG|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8875555|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:XP_016857451.1|refseq:XP_016857452.1|refseq:XP_016857453.1|dip:DIP-29106N	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:QtjMjJiMQF0CbTD40IZgca4XfIU9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:P63096	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-618639|ensembl:ENSP00000497051|ensembl:ENSP00000497179|ensembl:ENSP00000497260|ensembl:ENSP00000497315|ensembl:ENSP00000497379|ensembl:ENSP00000497717|ensembl:ENSP00000497754|ensembl:ENSP00000497760|ensembl:ENSP00000497765|ensembl:ENSP00000497773|ensembl:ENSP00000498091|ensembl:ENSP00000343027|ensembl:ENSP00000391439|ensembl:ENSP00000496800|ensembl:ENSP00000496829|uniprotkb:P04898|uniprotkb:P11015|uniprotkb:P31871|uniprotkb:Q5U074|uniprotkb:Q8TAN5|uniprotkb:Q9UGA4|uniprotkb:A8KA88|uniprotkb:B4E2V1|uniprotkb:C9J3A4	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:gnai1_human(display_long)|uniprotkb:GNAI1(gene name)|psi-mi:GNAI1(display_short)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-418594|ensembl:ENST00000351004(transcript)|ensembl:ENST00000442586(transcript)|ensembl:ENST00000648098(transcript)|ensembl:ENSG00000127955(gene)|ensembl:ENST00000648306(transcript)|ensembl:ENST00000648412(transcript)|ensembl:ENST00000648476(transcript)|ensembl:ENST00000648663(transcript)|ensembl:ENST00000648832(transcript)|ensembl:ENST00000648877(transcript)|ensembl:ENST00000648953(transcript)|ensembl:ENST00000649225(transcript)|ensembl:ENST00000649267(transcript)|ensembl:ENST00000649487(transcript)|ensembl:ENST00000649796(transcript)|ensembl:ENST00000649855(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63096|rcsb pdb:1KJY|rcsb pdb:1Y3A|rcsb pdb:2G83|rcsb pdb:2GTP|rcsb pdb:2IK8|rcsb pdb:2OM2|rcsb pdb:2XNS|rcsb pdb:3ONW|rcsb pdb:3QE0|rcsb pdb:3QI2|rcsb pdb:3UMR|rcsb pdb:3UMS|rcsb pdb:4G5Q|rcsb pdb:5JS7|rcsb pdb:5JS8|rcsb pdb:5TDH|rcsb pdb:6CMO|rcsb pdb:6CRK|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LML|rcsb pdb:6N4B|rcsb pdb:6OMM|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6QNO|rcsb pdb:6VU8|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7EB2|rcsb pdb:7JVR|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7O7F|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|refseq:NP_002060.4|refseq:NP_001243343.1	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:P04899	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-353997|uniprotkb:Q8IZ71|intact:EBI-2563889|uniprotkb:B4DYA0|intact:EBI-4404691|uniprotkb:Q6B6N3|uniprotkb:B3KTZ0|uniprotkb:B4E2X5|ensembl:ENSP00000312999	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:gnai2_human(display_long)|uniprotkb:GNAI2(gene name)|psi-mi:GNAI2(display_short)|uniprotkb:GNAI2B(gene name synonym)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_002061.1|refseq:NP_001269546.1|refseq:NP_001269549.1|refseq:NP_001269547.1|refseq:NP_001269548.1|refseq:NP_001159897.1|dip:DIP-602N|ensembl:ENSG00000114353(gene)|ensembl:ENST00000313601(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:0030425"(dendrite)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:6D9H|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|mint:P04899	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:Mi3PAXudkdPb375bOi7luNAmUaU9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:Q96AG4	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:O14654	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-356594|ensembl:ENSP00000505547	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:P27824	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:O00264	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1045534|uniprotkb:Q9UGJ9|ensembl:ENSP00000217971|uniprotkb:B7Z1L3	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001269550.1|ensembl:ENST00000217971(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|ensembl:ENSG00000101856(gene)|refseq:NP_006658.1	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:Q15084	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1043087|uniprotkb:Q6ZSH5|ensembl:ENSP00000272227|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|interpro:IPR036249|interpro:IPR044569|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|interpro:IPR017937|ensembl:ENSG00000143870(gene)|ensembl:ENST00000272227(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005733.1	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:411bo7TdfeCtMvUqyBb7bofi5To9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:Q13151	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-724092|ensembl:ENSP00000316042|intact:EBI-1043661|uniprotkb:Q6IB18	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:roa0_human(display_long)|uniprotkb:HNRPA0(gene name synonym)|uniprotkb:HNRNPA0(gene name)|psi-mi:HNRNPA0(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_006796.1|ensembl:ENSG00000177733(gene)|ensembl:ENST00000314940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006954"(inflammatory response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034801|interpro:IPR035979|mint:Q13151|reactome:R-HSA-72163|reactome:R-HSA-72203	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:buyQxR8FLxd4N6jRhwVsroeGrBw9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:P63000	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-413628|ensembl:ENSP00000258737|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q5JAA8|uniprotkb:Q9BTB4	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000136238(gene)|ensembl:ENST00000348035(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006954"(inflammatory response)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031529"(ruffle organization)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042470"(melanosome)|reactome:R-HSA-2424491|refseq:NP_008839.2|refseq:NP_061485.1|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051492"(regulation of stress fiber assembly)|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-389359|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-983231|reactome:R-HSA-2871796|reactome:R-HSA-376172|dip:DIP-29260N	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:Q60FE5	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1188279|uniprotkb:E9PHF0|ensembl:ENSP00000358872	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:q60fe5_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369856(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR044801|mint:Q60FE5|interpro:IPR036872	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:zZKLKGNmswqbaD6KKxlQ01pi9409606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:P57088	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1048629|uniprotkb:Q9H953|uniprotkb:B3KSS8|ensembl:ENSP00000422473|ensembl:ENSP00000427006|ensembl:ENSP00000441455	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:tmm33_human(display_long)|uniprotkb:Protein DB83(gene name synonym)|uniprotkb:TMEM33(gene name)|psi-mi:TMEM33(display_short)|uniprotkb:DB83(gene name synonym)|uniprotkb:SHINC-3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_060596.2|refseq:XP_005248173.1|refseq:XP_005248174.1|ensembl:ENSG00000109133(gene)|ensembl:ENST00000325094(transcript)|ensembl:ENST00000504986(transcript)|ensembl:ENST00000513702(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061024"(membrane organization)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR005344(Protein of unknown function UPF0121)|mint:P57088	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:FGc4/gpnYoRtlDJMxQWh5hXe5Ko9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:P26641	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:O95292	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:P61026	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_057215.3|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031489"(myosin V binding)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000084733(gene)|ensembl:ENST00000264710(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:Q9HAV0	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-358539|uniprotkb:B3KMH5|uniprotkb:D3DNR8|ensembl:ENSP00000501882|ensembl:ENSP00000502628|ensembl:ENSP00000232564	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:gbb4_human(display_long)|uniprotkb:GNB4(gene name)|psi-mi:GNB4(display_short)|uniprotkb:Transducin beta chain 4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_067642.1|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|reactome:R-HSA-456926|ensembl:ENSG00000114450(gene)|ensembl:ENST00000232564(transcript)|ensembl:ENST00000674862(transcript)|ensembl:ENST00000676128(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9HAV0|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|refseq:XP_006713784.1|refseq:XP_005247749.1	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:L6hFuZe1Luk8YTFW+posXDa2Qj49606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:P09543	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1059219|intact:EBI-1188262|ensembl:ENSP00000377470	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:cn37_human(display_long)|uniprotkb:CNP(gene name)|psi-mi:CNP(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_149124.3|refseq:XP_011522642.1|ensembl:ENSG00000173786(gene)|ensembl:ENST00000393892(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004113"(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009214"(cyclic nucleotide catabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031143"(pseudopodium)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042470"(melanosome)|go:"GO:0045202"(synapse)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417|mint:P09543|rcsb pdb:1WOJ|go:"GO:0003723"(RNA binding)|refseq:NP_001317145.1	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:TpzVM789s3qQKK7B00Vo92s31bY9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:P27797	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866|ensembl:ENSP00000466037	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_004334.1|ensembl:ENSG00000179218(gene)|ensembl:ENST00000316448(transcript)|ensembl:ENST00000586967(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|dip:DIP-104N	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:P08754	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-357563|uniprotkb:Q5TZX1|uniprotkb:P17539|ensembl:ENSP00000358867	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:gnai3_human(display_long)|uniprotkb:GNAI3(gene name)|psi-mi:GNAI3(display_short)|uniprotkb:"G(i) alpha-3"(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_006487.1|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|ensembl:ENSG00000065135(gene)|ensembl:ENST00000369851(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007049"(cell cycle)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0042588"(zymogen granule)|go:"GO:0045121"(membrane raft)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:2IHB|rcsb pdb:2ODE|rcsb pdb:2V4Z|rcsb pdb:4G5O|rcsb pdb:4G5R|rcsb pdb:4G5S|rcsb pdb:7E9H|rcsb pdb:7KH0|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-9009391|reactome:R-HSA-9660821	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:npLeIXVzrV8y0trCCII5rivIRYQ9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:P62873	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-357130|ensembl:ENSP00000367872|ensembl:ENSP00000481878|uniprotkb:P04901|uniprotkb:P04697|uniprotkb:B1AJZ7|uniprotkb:Q1RMY8	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:gbb1_human(display_long)|uniprotkb:GNB1(gene name)|psi-mi:GNB1(display_short)|uniprotkb:Transducin beta chain 1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62873|rcsb pdb:4KFM|rcsb pdb:4PNK|rcsb pdb:5HE0|rcsb pdb:5HE1|rcsb pdb:5HE2|rcsb pdb:5HE3|rcsb pdb:5UKK|rcsb pdb:5UKL|rcsb pdb:5UKM|rcsb pdb:5UZ7|rcsb pdb:6B3J|rcsb pdb:6CRK|rcsb pdb:6D9H|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6E3Y|rcsb pdb:6EG8|rcsb pdb:6G79|rcsb pdb:6GDG|rcsb pdb:6KPF|rcsb pdb:6KPG|go:"GO:1903561"(extracellular vesicle)|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6M8S|rcsb pdb:6N4B|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6OIJ|rcsb pdb:6OIK|rcsb pdb:6OMM|rcsb pdb:6ORV|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VMS|rcsb pdb:6VN7|rcsb pdb:6WHA|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:6XOX|rcsb pdb:7AUE|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX4|rcsb pdb:7D76|rcsb pdb:7D77|rcsb pdb:7D7M|rcsb pdb:7DFL|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7E9H|rcsb pdb:7CX3|rcsb pdb:7EB2|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7JVR|rcsb pdb:7K7L|rcsb pdb:7K7Z|rcsb pdb:7KH0|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7L1U|rcsb pdb:7L1V|rcsb pdb:7LCI|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-2485179|reactome:R-HSA-2514859|reactome:R-HSA-381676|reactome:R-HSA-381753|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|ensembl:ENST00000610897(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0097381"(photoreceptor disc membrane)|ensembl:ENSG00000078369(gene)|ensembl:ENST00000378609(transcript)|refseq:NP_001269467.1|refseq:NP_001269468.1|dip:DIP-599N|refseq:NP_002065.1|refseq:XP_016856548.1|refseq:XP_016856549.1|refseq:XP_016856550.1	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:zP/G70MXiSQpzbyyWFTWrJFQENk9606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48039	uniprotkb:P11021	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576579|imex:IM-24624-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	intact-crc:6D2A933DE79C8058|rigid:LoEbZ8LOu0t2tDpsegCXNlqvV+s	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:P63096	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-618639|ensembl:ENSP00000497051|ensembl:ENSP00000497179|ensembl:ENSP00000497260|ensembl:ENSP00000497315|ensembl:ENSP00000497379|ensembl:ENSP00000497717|ensembl:ENSP00000497754|ensembl:ENSP00000497760|ensembl:ENSP00000497765|ensembl:ENSP00000497773|ensembl:ENSP00000498091|ensembl:ENSP00000343027|ensembl:ENSP00000391439|ensembl:ENSP00000496800|ensembl:ENSP00000496829|uniprotkb:P04898|uniprotkb:P11015|uniprotkb:P31871|uniprotkb:Q5U074|uniprotkb:Q8TAN5|uniprotkb:Q9UGA4|uniprotkb:A8KA88|uniprotkb:B4E2V1|uniprotkb:C9J3A4	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:gnai1_human(display_long)|uniprotkb:GNAI1(gene name)|psi-mi:GNAI1(display_short)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-418594|ensembl:ENST00000351004(transcript)|ensembl:ENST00000442586(transcript)|ensembl:ENST00000648098(transcript)|ensembl:ENSG00000127955(gene)|ensembl:ENST00000648306(transcript)|ensembl:ENST00000648412(transcript)|ensembl:ENST00000648476(transcript)|ensembl:ENST00000648663(transcript)|ensembl:ENST00000648832(transcript)|ensembl:ENST00000648877(transcript)|ensembl:ENST00000648953(transcript)|ensembl:ENST00000649225(transcript)|ensembl:ENST00000649267(transcript)|ensembl:ENST00000649487(transcript)|ensembl:ENST00000649796(transcript)|ensembl:ENST00000649855(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63096|rcsb pdb:1KJY|rcsb pdb:1Y3A|rcsb pdb:2G83|rcsb pdb:2GTP|rcsb pdb:2IK8|rcsb pdb:2OM2|rcsb pdb:2XNS|rcsb pdb:3ONW|rcsb pdb:3QE0|rcsb pdb:3QI2|rcsb pdb:3UMR|rcsb pdb:3UMS|rcsb pdb:4G5Q|rcsb pdb:5JS7|rcsb pdb:5JS8|rcsb pdb:5TDH|rcsb pdb:6CMO|rcsb pdb:6CRK|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LML|rcsb pdb:6N4B|rcsb pdb:6OMM|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6QNO|rcsb pdb:6VU8|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7EB2|rcsb pdb:7JVR|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7O7F|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|refseq:NP_002060.4|refseq:NP_001243343.1	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE9606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:P11021	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:Q15084	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1043087|uniprotkb:Q6ZSH5|ensembl:ENSP00000272227|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|interpro:IPR036249|interpro:IPR044569|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|interpro:IPR017937|ensembl:ENSG00000143870(gene)|ensembl:ENST00000272227(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005733.1	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:411bo7TdfeCtMvUqyBb7bofi5To9606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:P53621	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:Q9NQX7	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-725459|uniprotkb:Q4G0A8|uniprotkb:Q53H84|uniprotkb:Q6IAE7|uniprotkb:Q86VK5|uniprotkb:Q8N288|uniprotkb:Q8TAW0|uniprotkb:Q9BUP8|uniprotkb:B3KPG4|ensembl:ENSP00000322730	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:itm2c_human(display_long)|uniprotkb:Transmembrane protein BRI3(gene name synonym)|uniprotkb:Cerebral protein 14(gene name synonym)|uniprotkb:ITM2C(gene name)|psi-mi:ITM2C(display_short)|uniprotkb:BRI3(gene name synonym)|uniprotkb:hucep-14(orf name)|uniprotkb:NPD018(orf name)|uniprotkb:PSEC0047(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001012532.1|refseq:NP_001012534.1|refseq:NP_112188.1|refseq:NP_001274169.1|refseq:NP_001274170.1|ensembl:ENSG00000135916(gene)|ensembl:ENST00000326427(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR007084(BRICHOS)|interpro:IPR040145	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:7PW4fTuwxueUI5cT1vYR3h+EHbo9606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:P27824	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:O15355	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-725702|ensembl:ENSP00000342778	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:O14654	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-356594|ensembl:ENSP00000505547	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:P08754	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-357563|uniprotkb:Q5TZX1|uniprotkb:P17539|ensembl:ENSP00000358867	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:gnai3_human(display_long)|uniprotkb:GNAI3(gene name)|psi-mi:GNAI3(display_short)|uniprotkb:"G(i) alpha-3"(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_006487.1|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|ensembl:ENSG00000065135(gene)|ensembl:ENST00000369851(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007049"(cell cycle)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0042588"(zymogen granule)|go:"GO:0045121"(membrane raft)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:2IHB|rcsb pdb:2ODE|rcsb pdb:2V4Z|rcsb pdb:4G5O|rcsb pdb:4G5R|rcsb pdb:4G5S|rcsb pdb:7E9H|rcsb pdb:7KH0|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-9009391|reactome:R-HSA-9660821	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:npLeIXVzrV8y0trCCII5rivIRYQ9606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:P42356	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-723050|uniprotkb:Q7Z625|uniprotkb:Q9UPG2|ensembl:ENSP00000255882|intact:EBI-11053324	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:pi4ka_human(display_long)|uniprotkb:PIK4CA(gene name synonym)|uniprotkb:PI4KA(gene name)|psi-mi:PI4KA(display_short)|uniprotkb:PIK4(gene name synonym)|uniprotkb:Phosphatidylinositol 4-Kinase III alpha(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000241973(gene)|ensembl:ENST00000255882(transcript)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0044803"(multi-organism membrane organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0046786"(viral replication complex formation and maintenance)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR042236|rcsb pdb:6BQ1|reactome:R-HSA-1483248|reactome:R-HSA-1660514|go:"GO:0016301"(kinase activity)|refseq:NP_477352.3	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:tm7wwZPJEvFMfK9xHMPLW9oYtzk9606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:Q9HAV0	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-358539|uniprotkb:B3KMH5|uniprotkb:D3DNR8|ensembl:ENSP00000501882|ensembl:ENSP00000502628|ensembl:ENSP00000232564	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:gbb4_human(display_long)|uniprotkb:GNB4(gene name)|psi-mi:GNB4(display_short)|uniprotkb:Transducin beta chain 4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_067642.1|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|reactome:R-HSA-456926|ensembl:ENSG00000114450(gene)|ensembl:ENST00000232564(transcript)|ensembl:ENST00000674862(transcript)|ensembl:ENST00000676128(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9HAV0|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|refseq:XP_006713784.1|refseq:XP_005247749.1	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:L6hFuZe1Luk8YTFW+posXDa2Qj49606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:P04899	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-353997|uniprotkb:Q8IZ71|intact:EBI-2563889|uniprotkb:B4DYA0|intact:EBI-4404691|uniprotkb:Q6B6N3|uniprotkb:B3KTZ0|uniprotkb:B4E2X5|ensembl:ENSP00000312999	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:gnai2_human(display_long)|uniprotkb:GNAI2(gene name)|psi-mi:GNAI2(display_short)|uniprotkb:GNAI2B(gene name synonym)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_002061.1|refseq:NP_001269546.1|refseq:NP_001269549.1|refseq:NP_001269547.1|refseq:NP_001269548.1|refseq:NP_001159897.1|dip:DIP-602N|ensembl:ENSG00000114353(gene)|ensembl:ENST00000313601(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:0030425"(dendrite)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:6D9H|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|mint:P04899	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:Mi3PAXudkdPb375bOi7luNAmUaU9606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:O60716	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:HgMvbcDKedE291TIvIOqLFT3srw9606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:P62879	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-356942|uniprotkb:P54312|uniprotkb:P11016|uniprotkb:B3KPU1|ensembl:ENSP00000305260|ensembl:ENSP00000377501|ensembl:ENSP00000377503	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:gbb2_human(display_long)|uniprotkb:GNB2(gene name)|psi-mi:GNB2(display_short)|uniprotkb:Transducin beta chain 2(gene name synonym)|uniprotkb:G protein subunit beta-2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_005264.2|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0031982"(vesicle)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62879|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|go:"GO:0016020"(membrane)|ensembl:ENSG00000172354(gene)|ensembl:ENST00000303210(transcript)|ensembl:ENST00000393924(transcript)|ensembl:ENST00000393926(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:dingPUxdpAhe7UMLquv0eqXNtUM9606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:Q60FE5	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1188279|uniprotkb:E9PHF0|ensembl:ENSP00000358872	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:q60fe5_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369856(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR044801|mint:Q60FE5|interpro:IPR036872	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:zZKLKGNmswqbaD6KKxlQ01pi9409606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:Q96QK1	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:EXkMduDQKNCdp876vGF5vna9t389606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49286	uniprotkb:P27348	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576613|imex:IM-24624-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N	-	-	-	figure legend:"Supplementary Table 1 (suite 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/09/22	2016/03/15	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	intact-crc:ABF4A65D69E2890D|rigid:kMsdKhaH45nmBhQtoBkfcVZFvLs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13618	uniprotkb:P48039	intact:EBI-456129|uniprotkb:O75415|uniprotkb:Q569L3|uniprotkb:Q9UBI8|uniprotkb:B8ZZC3|uniprotkb:Q9UET7|uniprotkb:A8K536|ensembl:ENSP00000264414	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:cul3_human(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:KIAA0617(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576651|imex:IM-24624-80	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003581.1|refseq:NP_001244126.1|refseq:NP_001244127.1|dip:DIP-31611N|ensembl:ENSG00000036257(gene)|ensembl:ENST00000264414(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000922"(spindle pole)|go:"GO:0001831"(trophectodermal cellular morphogenesis)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017145"(stem cell division)|go:"GO:0030030"(cell projection organization)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072576"(liver morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13618|rcsb pdb:2MYL|rcsb pdb:2MYM|rcsb pdb:4AP2|rcsb pdb:4APF|rcsb pdb:4EOZ|rcsb pdb:4HXI|rcsb pdb:5NLB|rcsb pdb:6I2M|reactome:R-HSA-4641258|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9706019|reactome:R-HSA-983168	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:xI/8pHB9nckOW629STOqKba4KzQ9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:D65034722CA2BE59|rigid:6o0zqVp698fbpnZK5gGiyyUO5bI	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46379	uniprotkb:P48039	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576642|imex:IM-24624-79	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:AF356E73F7ED44BB|rigid:2p/g/yoMIAIqYxPHiChAT4WZKjI	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P2N2	uniprotkb:P48039	intact:EBI-6872973|uniprotkb:Q9NW53|uniprotkb:Q8N4T3|uniprotkb:A8MQB7|uniprotkb:Q6P160|uniprotkb:A8MU88|ensembl:ENSP00000372964	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:rhg28_human(display_long)|uniprotkb:KIAA1314(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 28(gene name synonym)|uniprotkb:ARHGAP28(gene name)|psi-mi:ARHGAP28(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576678|imex:IM-24624-83	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000088756(gene)|ensembl:ENST00000383472(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1904425"(negative regulation of GTP binding)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-HSA-8980692	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:IYjZs2zg7OOFy5/mco/EhjGw1lE9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:D707CC5BCC467337|rigid:dsstmz0J0jBP6UOBC24ktBMjXq4	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q8WXI9	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644|ensembl:ENSP00000458280|ensembl:ENSP00000489184	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576669|imex:IM-24624-82	author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_065750.1|refseq:XP_005245421.1|dip:DIP-36054N|ensembl:ENSG00000143614(gene)|ensembl:ENSG00000261992(gene)|ensembl:ENST00000368655(transcript)|ensembl:ENST00000576342(transcript)|ensembl:ENST00000634544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606	intact-crc:43359E351954D499|rigid:Jsw8WkREBR0O/i7rZIs+/sA5qFA	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P42892	uniprotkb:P48039	intact:EBI-2859983|intact:EBI-2907408|uniprotkb:A8K3P1|uniprotkb:B4E291|uniprotkb:Q14217|uniprotkb:Q17RN5|uniprotkb:Q2Z2K8|uniprotkb:Q58GE7|uniprotkb:Q5THM5|uniprotkb:Q5THM7|uniprotkb:Q5THM8|uniprotkb:Q9UJQ6|uniprotkb:Q9UPF4|uniprotkb:Q9UPM4|uniprotkb:Q9Y501|ensembl:ENSP00000364028	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:ece1_human(display_long)|uniprotkb:ECE1(gene name)|psi-mi:ECE1(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576660|imex:IM-24624-81	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011539175.1|refseq:XP_006710461.1|refseq:XP_016856000.1|refseq:NP_001106819.1|refseq:NP_001106818.1|refseq:NP_001106820.1|refseq:NP_001388.1|ensembl:ENSG00000117298(gene)|ensembl:ENST00000374893(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0003100"(regulation of systemic arterial blood pressure by endothelin)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0007507"(heart development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010814"(substance P catabolic process)|go:"GO:0010815"(bradykinin catabolic process)|go:"GO:0010816"(calcitonin catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0031302"(intrinsic component of endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0034959"(endothelin maturation)|go:"GO:0042447"(hormone catabolic process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043583"(ear development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000718(Peptidase M13, neprilysin)|interpro:IPR008753(Peptidase M13)|interpro:IPR018497|interpro:IPR024079|interpro:IPR029734|interpro:IPR042089|rcsb pdb:3DWB|reactome:R-HSA-375276	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:Naxpnfs4LctZGDLImqijiMIKFvY9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:731EC17297160A58|rigid:YcSrUrYvjGnRuzTGZTi8PWxWiM4	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969Q6	uniprotkb:P48039	intact:EBI-2561661|uniprotkb:B4DEN7|uniprotkb:Q6P4G2|uniprotkb:Q9NWR9|uniprotkb:Q86TZ3|uniprotkb:Q5GJ56|uniprotkb:Q5GJ55|uniprotkb:D3DS97|uniprotkb:D3DS98|ensembl:ENSP00000261475	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:p2r3c_human(display_long)|uniprotkb:C14orf10(gene name synonym)|uniprotkb:G5PR(gene name synonym)|uniprotkb:Protein phosphatase subunit G5PR(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.6A/6C(gene name synonym)|uniprotkb:PPP2R3C(gene name)|psi-mi:PPP2R3C(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576705|imex:IM-24624-86	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001292085.1|refseq:NP_001292084.1|refseq:NP_060387.2|ensembl:ENSG00000092020(gene)|ensembl:ENST00000261475(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002759"(regulation of antimicrobial humoral response)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048536"(spleen development)|go:"GO:0051900"(regulation of mitochondrial depolarization)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR039865|interpro:IPR041534|mint:Q969Q6|refseq:XP_005267839.1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:kuXZ55Pqx8CoMysWfAjipVXHh9U9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:B0F6FC79CB706926|rigid:H3rC3hRZ1vAoLX4EAxFOq7fhgUs	false	-	sufficient binding region:294-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75970	uniprotkb:P48039	intact:EBI-821405|intact:EBI-2684724|uniprotkb:Q4LE30|uniprotkb:B7ZMI4|uniprotkb:A6NLC2|uniprotkb:O43798|uniprotkb:Q5CZ80|uniprotkb:Q5JTX3|uniprotkb:Q5JTX6|uniprotkb:Q5JTX7|uniprotkb:Q5JUC3|uniprotkb:Q5JUC4|uniprotkb:Q5VZ62|uniprotkb:Q8N790|intact:EBI-10961605|uniprotkb:B2RTS3|ensembl:ENSP00000320006	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:mpdz_human(display_long)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym)|uniprotkb:MPDZ(gene name)|psi-mi:MPDZ(display_short)|uniprotkb:MUPP1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576696|imex:IM-24624-85	author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006716948.1|refseq:XP_006716949.1|refseq:XP_006716950.1|refseq:XP_006716951.1|refseq:XP_006716952.1|refseq:XP_006716954.1|refseq:NP_003820.2|refseq:NP_001248335.1|refseq:NP_001248336.1|refseq:NP_001317566.1|refseq:XP_016870742.1|ensembl:ENSG00000107186(gene)|ensembl:ENST00000319217(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O75970|rcsb pdb:2FCF|rcsb pdb:2FNE|rcsb pdb:2IWN|rcsb pdb:2IWO|rcsb pdb:2IWP|rcsb pdb:2IWQ|rcsb pdb:2O2T|rcsb pdb:2OPG|rcsb pdb:2QG1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:Q5QzIDHLoL/sWqQI7r/Kb4VLSdY9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:C7A877792B48327D|rigid:qKqbVIloFHECWpGKvImjMTbc1SM	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P08253	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1033518|uniprotkb:B2R6U1|uniprotkb:Q9UCJ8|ensembl:ENSP00000219070|uniprotkb:E9PE45|uniprotkb:B4DWH3	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:mmp2_human(display_long)|uniprotkb:MMP2(gene name)|psi-mi:MMP2(display_short)|uniprotkb:CLG4A(gene name synonym)|uniprotkb:72 kDa gelatinase(gene name synonym)|uniprotkb:Matrix metalloproteinase-2(gene name synonym)|uniprotkb:Gelatinase A(gene name synonym)|uniprotkb:TBE-1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576687|imex:IM-24624-84	author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001289437.1|refseq:NP_001289438.1|refseq:NP_001289439.1|ensembl:ENSG00000087245(gene)|ensembl:ENST00000219070(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001955"(blood vessel maturation)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007566"(embryo implantation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030017"(sarcomere)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048771"(tissue remodeling)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071492"(cellular response to UV-A)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000585(Hemopexin)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR002477(Peptidoglycan binding-like)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR024079|interpro:IPR028708|interpro:IPR033739|interpro:IPR036365|interpro:IPR036375|interpro:IPR036943|rcsb pdb:1CK7|rcsb pdb:1CXW|rcsb pdb:1EAK|rcsb pdb:1GEN|rcsb pdb:1GXD|rcsb pdb:1HOV|rcsb pdb:1J7M|rcsb pdb:1KS0|rcsb pdb:1QIB|rcsb pdb:1RTG|rcsb pdb:3AYU|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-381426|reactome:R-HSA-3928665|reactome:R-HSA-6785807|reactome:R-HSA-9009391|refseq:NP_001121363.1|refseq:NP_004521.1	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:s0IHoSkzT9GNfkkLZsVsV7cIf1g9606	intact-crc:83C1FCF91E329871|rigid:d2aumzaYvA2OPrlJdBVCmROAjuI	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95295	uniprotkb:P48039	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576732|imex:IM-24624-89	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:943212BE4C544252|rigid:BIvKgzxtEHCd0aYA1EeMnFv4TuY	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q99496	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576723|imex:IM-24624-88	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	intact-crc:F93F66D7F6F34B45|rigid:PeYC45nX0vRE7Hi/m/dsVKKBImU	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12923	uniprotkb:P48039	intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576714|imex:IM-24624-87	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENST00000316707|ensembl:ENSP00000322675|ensembl:ENSP00000407249|ensembl:ENST00000427191|ensembl:ENSP00000408368|ensembl:ENST00000436978|ensembl:ENSP00000394794|ensembl:ENST00000511467|ensembl:ENSP00000426626|dip:DIP-40449N|ensembl:ENSG00000163629(gene)|ensembl:ENST00000411767(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|go:"GO:0001933"(negative regulation of protein phosphorylation)|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:BBC97F04444EC8D1|rigid:EHb65fgeb+MTwO5QDJzBkVzXyuk	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26640	uniprotkb:P48039	intact:EBI-355765|uniprotkb:Q5JQ90|uniprotkb:Q96E77|uniprotkb:Q9UQM2|uniprotkb:B4DZ61|uniprotkb:B0V1N1|ensembl:ENSP00000211402|ensembl:ENSP00000364815|ensembl:ENSP00000401121|ensembl:ENSP00000403359|ensembl:ENSP00000415316	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:syvc_human(display_long)|uniprotkb:VARS1(gene name)|psi-mi:VARS1(display_short)|uniprotkb:G7A(gene name synonym)|uniprotkb:Protein G7a(gene name synonym)|uniprotkb:VARS(gene name synonym)|uniprotkb:VARS2(gene name synonym)|uniprotkb:Valyl-tRNA synthetase(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576768|imex:IM-24624-93	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006286.1|ensembl:ENSG00000096171(gene)|ensembl:ENSG00000204394(gene)|ensembl:ENSG00000224264(gene)|ensembl:ENSG00000226589(gene)|ensembl:ENSG00000231116(gene)|ensembl:ENST00000211402(transcript)|ensembl:ENST00000375663(transcript)|ensembl:ENST00000422694(transcript)|ensembl:ENST00000435657(transcript)|ensembl:ENST00000457796(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004832"(valine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006438"(valyl-tRNA aminoacylation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002303(Valyl-tRNA synthetase, class Ia)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033705|interpro:IPR036282|interpro:IPR037118|mint:P26640|reactome:R-HSA-379716	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:aPfpK0/C2KpCsMOI0sjCreufI509606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:CF5E1965FE3298D7|rigid:ZLzE/6bW7IDtOlgJhJDQzyshqXc	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:P48039	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576759|imex:IM-24624-92	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:9F6973BB67FCE162|rigid:/t60qJEFuZf9CtlBnKle/25+5ig	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14669	uniprotkb:P48039	intact:EBI-308443|uniprotkb:Q15644|ensembl:ENSP00000283943|uniprotkb:D4HL82|uniprotkb:Q14CA3|uniprotkb:Q14CF1|uniprotkb:Q53R87|uniprotkb:Q53TE7	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:tripc_human(display_long)|uniprotkb:TRIP12(gene name)|psi-mi:TRIP12(display_short)|uniprotkb:Thyroid receptor-interacting protein 12(gene name synonym)|uniprotkb:KIAA0045(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase for Arf(gene name synonym)|uniprotkb:ULF(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase TRIP12(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576750|imex:IM-24624-91	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004229.1|refseq:NP_001271143.1|refseq:NP_001271144.1|refseq:NP_001271145.1|ensembl:ENSG00000153827(gene)|ensembl:ENST00000283943(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016607"(nuclear speck)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|interpro:IPR037197|mint:Q14669|reactome:R-HSA-983168|refseq:NP_001335244.1|refseq:NP_001335245.1|ensembl:ENSP00000283943|ensembl:ENST00000389044|ensembl:ENST00000389045|ensembl:ENSP00000373697|ensembl:ENSP00000373696|dip:DIP-58584N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	caution:This sequence has been withdrawn from Uniprot.|crc64:294A7C063A3332DE	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:wzXMKIUEDV4y7YE6PDU+LIPHl7U9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:9C8117A94D619087|rigid:IxDtkc9NnD0iOjbJQtaA36DVVeQ	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q4LDE5	uniprotkb:P48039	intact:EBI-2798103|uniprotkb:Q96JU7|uniprotkb:Q5VTE5|uniprotkb:Q5D213|uniprotkb:Q0P675|uniprotkb:Q9H284|uniprotkb:Q5T938|uniprotkb:Q9H8J9|uniprotkb:Q5VTE4|uniprotkb:Q7Z3G3|uniprotkb:Q7Z387|uniprotkb:Q8NBT9|ensembl:ENSP00000363593	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:svep1_human(display_long)|uniprotkb:C9orf13(gene name synonym)|uniprotkb:CCP22(gene name synonym)|uniprotkb:SELOB(gene name synonym)|uniprotkb:CCP module-containing protein 22(gene name synonym)|uniprotkb:Polydom(gene name synonym)|uniprotkb:Selectin-like osteoblast-derived protein(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-38(gene name synonym)|uniprotkb:SVEP1(gene name)|psi-mi:SVEP1(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576741|imex:IM-24624-90	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_699197.3|ensembl:ENST00000374461|ensembl:ENSP00000363585|ensembl:ENSP00000363593|ensembl:ENSG00000165124(gene)|ensembl:ENST00000374469(transcript)|go:"GO:0003017"(lymph circulation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007155"(cell adhesion)|go:"GO:0008544"(epidermis development)|go:"GO:0010467"(gene expression)|go:"GO:0016020"(membrane)|go:"GO:0036303"(lymph vessel morphogenesis)|go:"GO:0048014"(Tie signaling pathway)|go:"GO:0120193"(tight junction organization)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001759(Pentaxin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003410(Hyalin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011641(GCC2 and GCC3)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR035976|interpro:IPR036465	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:Eql8u2cebsRMv79rjBrmS/0b9Ec9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:4F33D22FD4B7E50A|rigid:qVUyDcm6fg9pjJcuz9YGkaFyquQ	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P21333	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576795|imex:IM-24624-96	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	intact-crc:D4F5E6A7B7160A39|rigid:GLvzOgg2rg9Z6IehF6tKpS4DIzk	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P35221	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576786|imex:IM-24624-95	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606	intact-crc:4523A0C12498321E|rigid:WxpGu//lnjgGysf7cFYaAwD5Whs	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63104	uniprotkb:P48039	intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576777|imex:IM-24624-94	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:F5AA068D198C98ED|rigid:LxxbbhedWp8y7WcIPQtT43IAC6c	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q8NFA0	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2511075|ensembl:ENSP00000300896|intact:EBI-9091112|uniprotkb:Q7Z5T3|uniprotkb:Q9Y591|uniprotkb:Q9BX85	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:ubp32_human(display_long)|uniprotkb:USP32(gene name)|psi-mi:USP32(display_short)|uniprotkb:USP10(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 32(gene name synonym)|uniprotkb:Deubiquitinating enzyme 32(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-60(gene name synonym)|uniprotkb:Ubiquitin thioesterase 32(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576831|imex:IM-24624-100	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000170832(gene)|ensembl:ENST00000300896(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR018247|interpro:IPR028889|interpro:IPR035927|interpro:IPR038765|interpro:IPR011992(EF-Hand type)|refseq:NP_115971.2|dip:DIP-53613N	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:DOnkgvUHy/ldOL9DCSP8PJppAY09606	intact-crc:124D83BF42DA02C1|rigid:zMLUKj/OP7rcNMzYbc2JiKjtWYA	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5T4S7	uniprotkb:P48039	intact:EBI-1995940|intact:EBI-1059327|uniprotkb:A8MPT2|uniprotkb:A8MQ33|uniprotkb:A8MQB1|uniprotkb:O60646|uniprotkb:O75050|uniprotkb:Q4QRK5|uniprotkb:Q5T4S8|uniprotkb:Q5T4S9|uniprotkb:Q5TBN8|uniprotkb:Q5TBP2|uniprotkb:Q6DKH8|uniprotkb:Q6P4A4|uniprotkb:Q7L8P7|uniprotkb:Q8IXJ4|uniprotkb:Q8TDN5|uniprotkb:Q8WV67|uniprotkb:Q9HA46|uniprotkb:Q9P2N9|uniprotkb:Q9UG82|ensembl:ENSP00000364403	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:ubr4_human(display_long)|uniprotkb:UBR4(gene name)|psi-mi:UBR4(display_short)|uniprotkb:KIAA0462(gene name synonym)|uniprotkb:KIAA1307(gene name synonym)|uniprotkb:RBAF600(gene name synonym)|uniprotkb:ZUBR1(gene name synonym)|uniprotkb:N-recognin-4(gene name synonym)|uniprotkb:Zinc finger UBR1-type protein 1(gene name synonym)|uniprotkb:Retinoblastoma-associated factor of 600 kDa(gene name synonym)|uniprotkb:600 kDa retinoblastoma protein-associated factor(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR4(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576822|imex:IM-24624-99	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065816.2|ensembl:ENST00000375218|ensembl:ENSP00000364403|ensembl:ENSP00000364366|ensembl:ENSG00000127481(gene)|ensembl:ENST00000375254(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025704|interpro:IPR036322|mint:Q5T4S7|reactome:R-HSA-6798695|reactome:R-HSA-983168	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:8Iown8oj965YAir+95+3om5+1YM9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:F18BDCB4264E65A2|rigid:FVpB8p8xKuqnxZl9mrKTFWzCHo0	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P29144	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1044672|uniprotkb:Q5VZU8|ensembl:ENSP00000365233	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:tpp2_human(display_long)|uniprotkb:Tripeptidyl-peptidase II(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:TPP2(gene name)|psi-mi:TPP2(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576813|imex:IM-24624-98	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_003282.2|ensembl:ENSG00000134900(gene)|ensembl:ENST00000376065(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022229|interpro:IPR022398|interpro:IPR023828|interpro:IPR034051|interpro:IPR036852|mint:P29144|reactome:R-HSA-983168|refseq:NP_001317517.1|dip:DIP-50761N	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:I+B6XApXumvX26aR5AdMhkhZVc49606	intact-crc:0DE5A2A2F5F585CD|rigid:7djja7DAZNg4wof57QsBzPeLHuE	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9Y490	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2462036|uniprotkb:A6NMY0|uniprotkb:Q86YD0|uniprotkb:Q9NZQ2|uniprotkb:Q9UHH8|uniprotkb:Q9UPX3|intact:EBI-28967697|ensembl:ENSP00000316029	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:tln1_human(display_long)|uniprotkb:TLN1(gene name)|psi-mi:TLN1(display_short)|uniprotkb:KIAA1027(gene name synonym)|uniprotkb:TLN(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576804|imex:IM-24624-97	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSP00000316029|refseq:NP_006280.3|ensembl:ENSG00000137076(gene)|ensembl:ENST00000314888(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0017166"(vinculin binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033622"(integrin activation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036476|interpro:IPR036723|interpro:IPR037438|mint:Q9Y490|rcsb pdb:1SYQ|rcsb pdb:2MWN|rcsb pdb:4DJ9|rcsb pdb:6R9T|reactome:R-HSA-114608|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381038|reactome:R-HSA-399955|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:C7FGaR2291KB6hBSloee5L8lYgA9606	intact-crc:10ECA363479F1703|rigid:5w4LBk127H3BuSsPDqXUvk8ygIY	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P09104	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-713154|ensembl:ENSP00000229277|ensembl:ENSP00000437402|ensembl:ENSP00000438873|uniprotkb:Q96J33|uniprotkb:B7Z2X9	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:enog_human(display_long)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Neural enolase(gene name synonym)|uniprotkb:Neuron-specific enolase(gene name synonym)|uniprotkb:Enolase 2(gene name synonym)|uniprotkb:ENO2(gene name)|psi-mi:ENO2(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576867|imex:IM-24624-104	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	rcsb pdb:2AKZ|rcsb pdb:3UCC|rcsb pdb:3UCD|rcsb pdb:3UJE|rcsb pdb:3UJF|rcsb pdb:3UJR|rcsb pdb:3UJS|rcsb pdb:4ZA0|rcsb pdb:4ZCW|rcsb pdb:5EU9|rcsb pdb:5IDZ|rcsb pdb:5TD9|rcsb pdb:5TIJ|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENST00000229277(transcript)|ensembl:ENST00000535366(transcript)|ensembl:ENST00000541477(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0043204"(perikaryon)|ensembl:ENSG00000111674(gene)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P09104|rcsb pdb:1TE6|rcsb pdb:2AKM|refseq:NP_001966.1	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:gNa8zN8RaWDRXjw/Z0sY6TAa/aA9606	intact-crc:CDE4C713325B2CE9|rigid:17lHwTTBC3mgXc7htK81iVWLVJY	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q14592	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2555738|uniprotkb:B4DNX9|uniprotkb:A4FU64|uniprotkb:Q2VPC7|uniprotkb:Q6VSF8|ensembl:ENSP00000353491	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:zn460_human(display_long)|uniprotkb:ZNF272(gene name synonym)|uniprotkb:Zinc finger protein 272(gene name synonym)|uniprotkb:Zinc finger protein HZF8(gene name synonym)|uniprotkb:ZNF460(gene name)|psi-mi:ZNF460(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576858|imex:IM-24624-103	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_006626.3|ensembl:ENSG00000197714(gene)|ensembl:ENST00000360338(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_001317551.1	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:MajnrRpwOQccWLawp3dN4rE5J189606	intact-crc:44729E31C2251B80|rigid:HN/G3dXLAh+KaLF7esbywvgW58I	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:O75152	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-748480|uniprotkb:Q6AHY4|uniprotkb:Q6AHY9|uniprotkb:Q6AW79|uniprotkb:Q6AWA1|uniprotkb:Q6PJK4|uniprotkb:Q86XZ7|ensembl:ENSP00000333253|ensembl:ENSP00000356179|ensembl:ENSP00000356181|ensembl:ENSP00000356183|ensembl:ENSP00000491830	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:zc11a_human(display_long)|uniprotkb:ZC3H11A(gene name)|psi-mi:ZC3H11A(display_short)|uniprotkb:KIAA0663(gene name synonym)|uniprotkb:ZC3HDC11A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576849|imex:IM-24624-102	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:XP_006711736.1|refseq:NP_055642.3|refseq:XP_011508501.1|refseq:XP_011508502.1|refseq:XP_011508503.1|refseq:XP_011508504.1|refseq:NP_001306167.1|refseq:NP_001306168.1|refseq:XP_005245700.1|refseq:XP_005245701.1|refseq:XP_016858445.1|refseq:XP_016858446.1|refseq:XP_016858447.1|refseq:XP_016858448.1|ensembl:ENSG00000058673(gene)|ensembl:ENST00000332127(transcript)|ensembl:ENST00000367210(transcript)|ensembl:ENST00000367212(transcript)|ensembl:ENST00000367214(transcript)|ensembl:ENST00000639812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR041686|mint:O75152|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:BJfX/K7kBXQGQx6l+Y2xBtwyJAw9606	intact-crc:0C3292E9B993FA1D|rigid:iR9a+zwbyomWd1PbIIs/LyOuxuQ	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q7Z5K2	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576840|imex:IM-24624-101	author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606	intact-crc:A3382F92CB376235|rigid:e0fex6Rv9Taler4TaEnL1XpZ234	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UIG0	uniprotkb:P48039	intact:EBI-927482|uniprotkb:O95039|uniprotkb:O95247|uniprotkb:O95277|uniprotkb:B9EGK3|uniprotkb:Q6P1K4|uniprotkb:Q86UJ6|uniprotkb:D3DXE9|ensembl:ENSP00000342434|ensembl:ENSP00000385442	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:baz1b_human(display_long)|uniprotkb:BAZ1B(gene name)|psi-mi:BAZ1B(display_short)|uniprotkb:WBSC10(gene name synonym)|uniprotkb:WBSCR9(gene name synonym)|uniprotkb:WSTF(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 9 protein(gene name synonym)|uniprotkb:Williams syndrome transcription factor(gene name synonym)|uniprotkb:WBSCR10(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 10 protein(gene name synonym)|uniprotkb:Bromodomain adjacent to zinc finger domain protein 1B(gene name synonym)|uniprotkb:hWALp2(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576903|imex:IM-24624-108	author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115784.1|refseq:XP_016868262.1|dip:DIP-35642N|ensembl:ENSG00000009954(gene)|ensembl:ENST00000339594(transcript)|ensembl:ENST00000404251(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0035173"(histone kinase activity)|go:"GO:0042393"(histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037375|mint:Q9UIG0|rcsb pdb:1F62|rcsb pdb:5NNF|reactome:R-HSA-5250924|reactome:R-HSA-5693565	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:1GTflhs9UUxTv4SPOYPKmuKAtSQ9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:BA8F133312C0628D|rigid:YLzf+B0ng6hDDfQf+y3H0JX3QC0	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9NRL2	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-927511|uniprotkb:Q9NZ15|uniprotkb:Q9P065|uniprotkb:Q9UIG1|uniprotkb:Q9Y3V3|ensembl:ENSP00000353458|ensembl:ENSP00000371859	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:baz1a_human(display_long)|uniprotkb:BAZ1A(gene name)|psi-mi:BAZ1A(display_short)|uniprotkb:ACF1(gene name synonym)|uniprotkb:WCRF180(gene name synonym)|uniprotkb:HSPC317(orf name)|uniprotkb:ATP-utilizing chromatin assembly and remodeling factor 1(gene name synonym)|uniprotkb:ATP-dependent chromatin-remodeling protein(gene name synonym)|uniprotkb:Williams syndrome transcription factor-related chromatin-remodeling factor 180(gene name synonym)|uniprotkb:CHRAC subunit ACF1(gene name synonym)|uniprotkb:hWALp1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576894|imex:IM-24624-107	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_038476.2|refseq:NP_872589.1|dip:DIP-36071N|ensembl:ENSG00000198604(gene)|ensembl:ENST00000360310(transcript)|ensembl:ENST00000382422(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008623"(CHRAC)|go:"GO:0016573"(histone acetylation)|go:"GO:0016590"(ACF complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037325|rcsb pdb:5UIY	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:1N6/uH2kUWs1/HdPhSI2a/UnbqI9606	intact-crc:CE1FB656109860EA|rigid:HEEN+QiWhJLWrvJ4/750UW1HTag	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6UB98	uniprotkb:P48039	intact:EBI-2690224|uniprotkb:Q658K1|uniprotkb:Q6QMF7|uniprotkb:Q9H784|uniprotkb:O94951|uniprotkb:Q9H231|ensembl:ENSP00000262126	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:anr12_human(display_long)|uniprotkb:ANCO2(gene name synonym)|uniprotkb:KIAA0874(gene name synonym)|uniprotkb:Ankyrin repeat-containing cofactor 2(gene name synonym)|uniprotkb:GAC-1 protein(gene name synonym)|uniprotkb:ANKRD12(gene name)|psi-mi:ANKRD12(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576885|imex:IM-24624-106	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016881152.1|refseq:NP_001077094.1|refseq:NP_001190985.1|refseq:NP_056023.3|refseq:XP_005258149.1|refseq:XP_005258150.1|ensembl:ENSG00000101745(gene)|ensembl:ENST00000262126(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:etb60/sLQAg6in0go8JlQEGA9Os9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:E7425ACCC36E90D8|rigid:AqBEiXvAV2ly4kGWjHnd3hd4pQ0	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P55209	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576876|imex:IM-24624-105	author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	intact-crc:D2F262D34B22DECA|rigid:3NvQjB9rhB5hQCYennOmT3zRwF8	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14578	uniprotkb:P48039	intact:EBI-8623109|ensembl:ENSP00000261833|uniprotkb:Q6XUH8|intact:MINT-2795177|uniprotkb:Q2M5E1|uniprotkb:Q9UPZ7|uniprotkb:Q86UQ9	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:ctro_human(display_long)|uniprotkb:CIT(gene name)|psi-mi:CIT(display_short)|uniprotkb:KIAA0949(gene name synonym)|uniprotkb:STK21(gene name synonym)|uniprotkb:CRIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 21(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576930|imex:IM-24624-111	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000122966(gene)|ensembl:ENST00000261833(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017405(Citron Rho-interacting kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037708|mint:O14578|reactome:R-HSA-5625900|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0005737"(cytoplasm)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048699"(generation of neurons)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|refseq:NP_001193928.1|refseq:NP_009105.1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	function:Required for KIF14 localization to the central spindle and midbody. May play a role in cytokinesis. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system|comment:mint	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:yA7y17lwftFoF2/BfbtC3aanJaI9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:1E4B9A3905BAABDA|rigid:4YH/EcTpRCtgUSFhbfdm599hkGU	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q14839	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576921|imex:IM-24624-110	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606	intact-crc:DCD862CF193ED292|rigid:2tr+Pj5G3NawbMJm6mQ521Litno	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14209	uniprotkb:P48039	intact:EBI-748547|uniprotkb:O00518|uniprotkb:Q6ICV7|uniprotkb:A6NIW1|ensembl:ENSP00000370588	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:cd99_human(display_long)|uniprotkb:T-cell surface glycoprotein E2(gene name synonym)|uniprotkb:E2 antigen(gene name synonym)|uniprotkb:Protein MIC2(gene name synonym)|uniprotkb:12E7(gene name synonym)|uniprotkb:CD99(gene name)|psi-mi:CD99(display_short)|uniprotkb:MIC2(gene name synonym)|uniprotkb:MIC2X(gene name synonym)|uniprotkb:MIC2Y(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576912|imex:IM-24624-109	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001116370.1|refseq:NP_002405.1|refseq:NP_001308296.1|refseq:NP_001308297.1|refseq:NP_001308298.1|ensembl:ENSG00000002586(gene)|ensembl:ENST00000381192(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0072683"(T cell extravasation)|go:"GO:2000391"(positive regulation of neutrophil extravasation)|interpro:IPR022078|reactome:R-HSA-198933|reactome:R-HSA-202733	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:g0uUrvPtgp5eBwP7RXnQa0Ij6GU9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:BE12C9C392A009BC|rigid:qMFlMIFLfPCDSu6/LIzSnJRUMb8	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9Y3D0	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-744045|ensembl:ENSP00000387471	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:cia2b_human(display_long)|uniprotkb:CIAO2B(gene name)|psi-mi:CIAO2B(display_short)|uniprotkb:CIAB(gene name synonym)|uniprotkb:FAM96B(gene name synonym)|uniprotkb:MIP18(gene name synonym)|uniprotkb:MSS19-interacting protein of 18 kDa(gene name synonym)|uniprotkb:Mitotic spindle-associated MMXD complex subunit MIP18(gene name synonym)|uniprotkb:Protein FAM96B(gene name synonym)|uniprotkb:CGI-128(orf name)|uniprotkb:HSPC118(orf name)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576966|imex:IM-24624-115	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_057146.1|ensembl:ENSG00000166595(gene)|ensembl:ENST00000422424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030496"(midbody)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|mint:Q9Y3D0|reactome:R-HSA-2564830	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:6LfOUjTAKuEjop3XVyyxx6c4Wl09606	intact-crc:FF6DDF6734355768|rigid:Esm4HhiaLVGaQRxOmrMspPxDEnA	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P42566	uniprotkb:P48039	intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576957|imex:IM-24624-114	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:3D57C9FE08843784|rigid:hqLE0Rcec3DD32kgLYFFm9QxGIY	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q14999	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-308606|uniprotkb:Q5T654|ensembl:ENSP00000265348|uniprotkb:B4DYZ0|uniprotkb:F5H0L1	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:cul7_human(display_long)|uniprotkb:CUL7(gene name)|psi-mi:CUL7(display_short)|uniprotkb:KIAA0076(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576948|imex:IM-24624-113	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000044090(gene)|ensembl:ENST00000265348(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001890"(placenta development)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:1990393"(3M complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR021097|interpro:IPR031223|interpro:IPR036317|interpro:IPR036388|mint:Q14999|rcsb pdb:2JNG|reactome:R-HSA-381038|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001161842.1|refseq:NP_055595.2|dip:DIP-31618N|dip:DIP-60187N	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:8sODZSppCsuEgRmhSHp3UjwOf2M9606	intact-crc:4E8002D8BC62DE27|rigid:Dm/iqAQNeyfIlcQQYa9PaVF+MnU	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9Y6N1	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2963275|uniprotkb:I3L220|ensembl:ENSP00000299335|ensembl:ENSP00000459901|uniprotkb:Q6FHB7|uniprotkb:Q9BRX0|uniprotkb:Q9UME8|uniprotkb:D3DTY5	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:cox11_human(display_long)|uniprotkb:COX11(gene name)|psi-mi:COX11(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576939|imex:IM-24624-112	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000166260(gene)|ensembl:ENST00000299335(transcript)|ensembl:ENST00000576370(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0009055"(electron transfer activity)|go:"GO:0031304"(intrinsic component of mitochondrial inner membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0055065"(metal ion homeostasis)|interpro:IPR007533(Cytochrome c oxidase assembly protein CtaG/Cox11)|interpro:IPR023471|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|refseq:NP_004366.1|refseq:XP_011522644.1|refseq:XP_016879681.1|refseq:XP_016879682.1|refseq:XP_016879683.1|refseq:XP_016879684.1|refseq:XP_016879685.1	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:inklcaALt6Jb0Cs/4ckzcG6YrHA9606	intact-crc:A5342890DEDE56C2|rigid:4rOfryHYLHRXjUYpeiecT2NpdBc	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P31629	uniprotkb:P48039	intact:EBI-2514157|ensembl:ENSP00000012134|ensembl:ENSP00000356575|ensembl:ENSP00000356576|uniprotkb:Q02646|uniprotkb:Q9NS05|uniprotkb:Q5THT5	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:zep2_human(display_long)|uniprotkb:HIVEP2(gene name)|psi-mi:HIVEP2(display_short)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 2(gene name synonym)|uniprotkb:MHC-binding protein 2(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577002|imex:IM-24624-119	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000010818(gene)|ensembl:ENST00000012134(transcript)|ensembl:ENST00000367603(transcript)|ensembl:ENST00000367604(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:XP_016866294.1|refseq:NP_006725.3	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:/QXXmthWJq/FkgWwIqkVb1z16EU9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:5E127A7FFC864316|rigid:oQJgHzRMXBRmCw8RUQ42C1J/8Gw	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q969S8	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-301762|uniprotkb:Q08AP4|uniprotkb:Q6STF9|uniprotkb:Q96P77|uniprotkb:Q96P78|uniprotkb:Q9H028|uniprotkb:Q9UGX1|uniprotkb:Q9UGX2|ensembl:ENSP00000216271	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:hda10_human(display_long)|uniprotkb:HDAC10(gene name)|psi-mi:HDAC10(display_short)|uniprotkb:Histone deacetylase 10(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576993|imex:IM-24624-118	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001152758.1|refseq:NP_114408.3|ensembl:ENSG00000100429(gene)|ensembl:ENST00000216271(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0016236"(macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035825"(homologous recombination)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047609"(acetylputrescine deacetylase activity)|go:"GO:0047611"(acetylspermidine deacetylase activity)|go:"GO:0106047"(polyamine deacetylation)|go:"GO:0106048"(spermidine deacetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:LPCw1AIbzupSEHpFjokLtserSOI9606	intact-crc:C88F262E714F0D27|rigid:euY68AnKtPvDMRZAoO++YfszgcE	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9HCG7	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2869236|uniprotkb:Q96SJ2|uniprotkb:Q96LY1|uniprotkb:Q9H2L8|uniprotkb:Q96A51|uniprotkb:Q5TCV6|uniprotkb:D3DRP2|ensembl:ENSP00000367343	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:gba2_human(display_long)|uniprotkb:GBA2(gene name)|psi-mi:GBA2(display_short)|uniprotkb:KIAA1605(gene name synonym)|uniprotkb:Beta-glucocerebrosidase 2(gene name synonym)|uniprotkb:Glucosylceramidase 2(gene name synonym)|uniprotkb:Bile acid beta-glucosidase GBA2(gene name synonym)|uniprotkb:Bile acid glucosyl transferase GBA2(gene name synonym)|uniprotkb:Cholesterol glucosyltransferase GBA2(gene name synonym)|uniprotkb:Cholesteryl-beta-glucosidase GBA2(gene name synonym)|uniprotkb:SPG46(gene name synonym)|uniprotkb:AD035(orf name)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576984|imex:IM-24624-117	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_065995.1|refseq:NP_001317589.1|refseq:XP_016870435.1|go:"GO:0016139"(glycoside catabolic process)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030259"(lipid glycosylation)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0046527"(glucosyltransferase activity)|go:"GO:0050295"(steryl-beta-glucosidase activity)|go:"GO:0090498"(extrinsic component of Golgi membrane)|go:"GO:0097035"(regulation of membrane lipid distribution)|interpro:IPR006775(Protein of unknown function DUF608)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR014551(Beta-glucosidase, GBA2 type)|interpro:IPR024462|reactome:R-HSA-1660662|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0008422"(beta-glucosidase activity)|go:"GO:0016021"(integral component of membrane)|ensembl:ENSG00000070610(gene)|ensembl:ENST00000378103(transcript)|go:"GO:0004348"(glucosylceramidase activity)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006680"(glucosylceramide catabolic process)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0007417"(central nervous system development)	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:3KDl8N0NifvvRgcyZPQ1grsDJ/w9606	intact-crc:7AA23842E2390717|rigid:ZmU92Zt0dlE7nP7duW6s9mZGryE	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P02751	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11576975|imex:IM-24624-116	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2019/10/18	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:BCD927AD161E79BC|rigid:O2CZPSjJX5Bg9JffEkOgjyX9jkQ	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2M5	uniprotkb:P48039	intact:EBI-714379|ensembl:ENSP00000209884|uniprotkb:Q5TZF2|uniprotkb:Q9H457|uniprotkb:B3KMA0|uniprotkb:Q5ZF45|uniprotkb:B4DUR0	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:klh20_human(display_long)|uniprotkb:KLHL20(gene name)|psi-mi:KLHL20(display_short)|uniprotkb:KLEIP(gene name synonym)|uniprotkb:Kelch-like ECT2-interacting protein(gene name synonym)|uniprotkb:Kelch-like protein X(gene name synonym)|uniprotkb:KLHLX(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577038|imex:IM-24624-123	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-HSA-983168|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1990390"(protein K33-linked ubiquitination)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030594|mint:Q9Y2M5|rcsb pdb:5YQ4|rcsb pdb:6GY5|reactome:R-HSA-8951664|ensembl:ENSG00000076321(gene)|ensembl:ENST00000209884(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019964"(interferon-gamma binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|refseq:NP_055273.2|refseq:XP_005245150.1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:3MyNIHmvjvjumxy4csUdrbMg5wI9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:C2B1C96ED8AB9CA0|rigid:dsKQbHToGJBbg+T2/UFuGgOkh2c	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IY22	uniprotkb:P48039	intact:EBI-7689652|ensembl:ENSP00000446100|uniprotkb:Q9C0G9|intact:MINT-7383621	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:cmip_human(display_long)|uniprotkb:CMIP(gene name)|psi-mi:CMIP(display_short)|uniprotkb:KIAA1694(gene name synonym)|uniprotkb:TCMIP(gene name synonym)|uniprotkb:Truncated c-Maf-inducing protein(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577029|imex:IM-24624-122	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000153815(gene)|ensembl:ENST00000537098(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR032675|mint:Q8IY22|refseq:NP_938204.2|refseq:NP_085132.1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	comment:mint	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:5wBgX9IBfu2NMeP50j0DSrQN4rI9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:4B5684764306BC2E|rigid:R6WWBY1aQGzjTqGh+6FUe9iTMcc	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q2M389	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2563783|uniprotkb:Q8IW61|uniprotkb:Q9NVD6|uniprotkb:Q8N5W7|uniprotkb:Q2NL83|uniprotkb:Q9UPW7|ensembl:ENSP00000328062	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:wasc4_human(display_long)|uniprotkb:WASHC4(gene name)|psi-mi:WASHC4(display_short)|uniprotkb:KIAA1033(gene name synonym)|uniprotkb:Strumpellin and WASH-interacting protein(gene name synonym)|uniprotkb:WASH complex subunit SWIP(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577020|imex:IM-24624-121	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_056090.1|ensembl:ENSG00000136051(gene)|ensembl:ENST00000332180(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0071203"(WASH complex)|go:"GO:0140591"(nuclear envelope budding)|interpro:IPR027307|interpro:IPR028191|interpro:IPR028283|interpro:IPR028282|refseq:NP_001280569.1	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:APnP9mxAqwzKEoQFGt94Z8Y73t49606	intact-crc:C46A056E10ABA5DD|rigid:LLZpQAlI84yH3Dhzgwm7H9reRjk	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96P70	uniprotkb:P48039	intact:EBI-356319|intact:EBI-1059309|uniprotkb:Q8N1Y1|uniprotkb:Q8N3I2|uniprotkb:Q8NCG9|uniprotkb:Q96SU6|uniprotkb:Q9NW01|uniprotkb:Q9P0A8|uniprotkb:Q9ULM8|ensembl:ENSP00000354742|uniprotkb:B1ASV5	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:ipo9_human(display_long)|uniprotkb:HSPC273(orf name)|uniprotkb:IPO9(gene name)|psi-mi:IPO9(display_short)|uniprotkb:IMP9(gene name synonym)|uniprotkb:KIAA1192(gene name synonym)|uniprotkb:RANBP9(gene name synonym)|uniprotkb:Ran-binding protein 9(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577011|imex:IM-24624-120	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060555.2|ensembl:ENSG00000198700(gene)|ensembl:ENST00000361565(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|mint:Q96P70|rcsb pdb:6N1Z	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:jsjQSBULeF1L2FlDcPZouMz6pJE9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:AB5FC700FA6F89E6|rigid:3MTcA44DX5z/MA3f4eUP6nXAWKU	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14696	uniprotkb:P48039	intact:EBI-6165891|ensembl:ENSP00000261758|ensembl:ENSP00000453430|ensembl:ENSP00000482455|uniprotkb:D3DW96|uniprotkb:Q969U1|uniprotkb:B4DW84	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:mesd_human(display_long)|uniprotkb:MESD(gene name)|psi-mi:MESD(display_short)|uniprotkb:KIAA0081(gene name synonym)|uniprotkb:LDLR chaperone MESD(gene name synonym)|uniprotkb:MESDC2(gene name synonym)|uniprotkb:MESDM(gene name synonym)|uniprotkb:Mesoderm development LRP chaperone MESD(gene name synonym)|uniprotkb:Mesoderm development candidate 2(gene name synonym)|uniprotkb:Mesoderm development protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-61(gene name synonym)|uniprotkb:UNQ1911/PRO4369(orf name)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577065|imex:IM-24624-126	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000117899(gene)|ensembl:ENST00000261758(transcript)|ensembl:ENST00000619987(transcript)|go:"GO:0001503"(ossification)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|ensembl:ENST00000561312(transcript)|go:"GO:0006909"(phagocytosis)|go:"GO:0007498"(mesoderm development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042802"(identical protein binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:1904395"(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR019330|mint:Q14696|refseq:NP_055969.1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:PO/8DDUMQwmzmwLpGYdFJWIUdB09606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:BFB2F6B7F6C12CB7|rigid:e7JQNh2GrHzWdha5x7J4jblYZa8	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q14974	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577056|imex:IM-24624-125	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	intact-crc:C6E355DF6F72C9BC|rigid:dELEMNSQ5ld7cYvFToLkh5erG00	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q59HD9	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11573630	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:q59hd9_human(display_long)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577047|imex:IM-24624-124	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017096(Kelch-like protein, gigaxonin)|refseq:NP_001165125.1|interpro:IPR030606|interpro:IPR015915(Kelch-type beta propeller)	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:wHknVs3AgC8HJ+0Mcd7v62uQ7ak9606	intact-crc:80A0FA20EBE94547|rigid:GwNkNz8HppynX8odwSpvPULkloU	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49321	uniprotkb:P48039	intact:EBI-716205|uniprotkb:Q53GW5|uniprotkb:Q5T625|uniprotkb:Q5T622|uniprotkb:Q96A69|uniprotkb:Q9BTW2|uniprotkb:A8K6H2|uniprotkb:B4DQP3|uniprotkb:F5H3J2|uniprotkb:D3DQ07|intact:EBI-28989159|ensembl:ENSP00000255120	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:nasp_human(display_long)|uniprotkb:NASP(gene name)|psi-mi:NASP(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577092|imex:IM-24624-129	author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182122.1|refseq:NP_002473.2|refseq:NP_689511.2|ensembl:ENSG00000132780(gene)|ensembl:ENST00000350030(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0008584"(male gonad development)|go:"GO:0015031"(protein transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019544|interpro:IPR019734|mint:P49321|ensembl:ENSP00000255120|ensembl:ENST00000351223|ensembl:ENSP00000255121|ensembl:ENST00000537798|ensembl:ENSP00000438871|refseq:XP_005270945.1|dip:DIP-47269N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:8BOknyp+vOh6NF+fXZPYbbqFbH49606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:FA3F47E59C9E6DCA|rigid:W32tkbMQz++B5h2Z8MMFP7NL31k	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99733	uniprotkb:P48039	intact:EBI-2255116|uniprotkb:B2R6J4|uniprotkb:F5HFY4|ensembl:ENSP00000369915|ensembl:ENSP00000483728	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:np1l4_human(display_long)|uniprotkb:NAP1L4(gene name)|psi-mi:NAP1L4(display_short)|uniprotkb:NAP2(gene name synonym)|uniprotkb:Nucleosome assembly protein 2(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577083|imex:IM-24624-128	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005960.1|ensembl:ENSG00000205531(gene)|ensembl:ENSG00000273562(gene)|ensembl:ENST00000380542(transcript)|ensembl:ENST00000619695(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q99733	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:tES8IJDlW4JONR/pdC8dq49I/7Y9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:FF1D4BF496235394|rigid:+nbmQOAcmcedi/XwMQ/gvX8/bbk	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q96T76	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1044169|uniprotkb:Q9BYS9|uniprotkb:Q17RZ8|uniprotkb:Q5T455|uniprotkb:Q66K82|uniprotkb:Q7L4W8|uniprotkb:Q969Z1|uniprotkb:Q96DF1|uniprotkb:Q96MR1|uniprotkb:Q96RK5|uniprotkb:Q96SK1|uniprotkb:Q9BUE2|ensembl:ENSP00000359818|ensembl:ENSP00000412698|uniprotkb:D3DR55|uniprotkb:B0QZ75|uniprotkb:B3KPE5|uniprotkb:B4DQX2|uniprotkb:B4E2I3|uniprotkb:F8W9Y2	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:mms19_human(display_long)|uniprotkb:MMS19(gene name)|psi-mi:MMS19(display_short)|uniprotkb:MMS19L(gene name synonym)|uniprotkb:MMS19-like protein(gene name synonym)|uniprotkb:MET18 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577074|imex:IM-24624-127	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000155229(gene)|ensembl:ENST00000370782(transcript)|ensembl:ENST00000438925(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|mint:Q96T76|reactome:R-HSA-2564830|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009725"(response to hormone)|go:"GO:0016020"(membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0019899"(enzyme binding)|refseq:NP_071757.4|refseq:NP_001276332.1|refseq:NP_001276333.1|refseq:NP_001276334.1|refseq:NP_001317057.1|refseq:XP_016872013.1	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:sujw9MQiwau6A0dumVM7gXVMGjE9606	intact-crc:D8C4792F3CE3834B|rigid:xaIci/tOZX53bO1OR1WOOcFoAew	false	sufficient binding region:208-239	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P2R7	uniprotkb:P48039	intact:EBI-2269898|uniprotkb:O95194|uniprotkb:Q5T9Q4|uniprotkb:Q5T9Q6|uniprotkb:Q9NV21|uniprotkb:Q9NVP7|uniprotkb:B2RDE7|ensembl:ENSP00000494360|ensembl:ENSP00000494987	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:sucb1_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)|uniprotkb:ATP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-A chain(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577119|imex:IM-24624-132	author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003841.1|ensembl:ENSG00000136143(gene)|ensembl:ENST00000643584(transcript)|ensembl:ENST00000646932(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006781"(succinyl-CoA pathway)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034723|mint:Q9P2R7|rcsb pdb:6G4Q|reactome:R-HSA-71403	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:I/FQp3c8ckxpxoyftKge2B5lDmI9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:0B38C3B48ADCE0EA|rigid:JZ7AgzPeUKiy+hx7wLKQcSqjq7Q	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14997	uniprotkb:P48039	intact:EBI-1236916|uniprotkb:Q1XBG4|uniprotkb:Q1XBG5|uniprotkb:Q1XBG6|uniprotkb:Q2M1Z0|uniprotkb:Q6IPR2|uniprotkb:Q86XF8|ensembl:ENSP00000384211	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:psme4_human(display_long)|uniprotkb:PSME4(gene name)|psi-mi:PSME4(display_short)|uniprotkb:KIAA0077(gene name synonym)|uniprotkb:Proteasome activator PA200(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577110|imex:IM-24624-131	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055429.2|dip:DIP-38203N|ensembl:ENSG00000068878(gene)|ensembl:ENST00000404125(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070628"(proteasome binding)|go:"GO:1990111"(spermatoproteasome complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021843|interpro:IPR032430|interpro:IPR035309|mint:Q14997|rcsb pdb:6KWX|rcsb pdb:6KWY|rcsb pdb:6REY|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-8932339	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:wKVv+GwMVpoOZZS1eNP+rDe85tE9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:89B73147AE14D142|rigid:d2oRPMFuBFTRLJH7cf7WEc6kS+o	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13200	uniprotkb:P48039	intact:EBI-357648|uniprotkb:B4DX07|uniprotkb:B4DXY1|uniprotkb:E7EW34|uniprotkb:E9PCS3|uniprotkb:Q12932|uniprotkb:Q15321|uniprotkb:Q96I12|ensembl:ENSP00000310129|uniprotkb:Q53XQ4	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:psmd2_human(display_long)|uniprotkb:PSMD2(gene name)|psi-mi:PSMD2(display_short)|uniprotkb:TRAP2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)|uniprotkb:Protein 55.11(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577101|imex:IM-24624-130	author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265637.1|refseq:NP_001265638.1|refseq:NP_002799.3|ensembl:ENSG00000175166(gene)|ensembl:ENST00000310118(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040892|interpro:IPR041433|mint:Q13200|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|rcsb pdb:5VHM|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:6MSB|rcsb pdb:6MSD|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-5668541|dip:DIP-38204N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:wujS1i4Gs3gWNinOey4oKsshA+g9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:451512E9FB4FA49B|rigid:MFUNSDKykKRkmTFwZtFE03YZFsw	false	-	sufficient binding region:208-239	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q10567	uniprotkb:P49286	intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000319361|ensembl:ENSP00000350199|ensembl:ENSP00000384194|ensembl:ENSP00000400065	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577128|imex:IM-24624-133	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001118.3|refseq:NP_663782.2|refseq:NP_001159491.1|ensembl:ENSG00000100280(gene)|ensembl:ENST00000317368(transcript)|ensembl:ENST00000357586(transcript)|ensembl:ENST00000405198(transcript)|ensembl:ENST00000432560(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001822"(kidney development)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|rcsb pdb:6CRI|dip:DIP-24207N	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/16	rogid:D0i+5PXwzbBmOSyeCOSFKZx8fQk9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:18207BAAA7008F75|rigid:R0HXsfFu5zt9ipnrXyVk2t66R+E	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P12814	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577146|imex:IM-24624-134	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001093.1|refseq:NP_001123477.1|refseq:NP_001123476.1|dip:DIP-33184N|ensembl:ENSG00000072110(gene)|ensembl:ENST00000193403(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:guTURyt26f1ort4NAlYyabNc+WE9606	intact-crc:B8B5DBA0C9F58510|rigid:SNt2MIZJjWjizlLd5+WKfEOeYg4	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UH73	uniprotkb:P49286	intact:EBI-765426|uniprotkb:Q8IW11|ensembl:ENSP00000322898	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:coe1_human(display_long)|uniprotkb:Early B-cell factor(gene name synonym)|uniprotkb:EBF1(gene name)|psi-mi:EBF1(display_short)|uniprotkb:COE1(gene name synonym)|uniprotkb:EBF(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577173|imex:IM-24624-137	author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_874367.1|refseq:NP_076870.1|ensembl:ENSG00000164330(gene)|ensembl:ENST00000313708(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR003523(Transcription factor COE)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018350|interpro:IPR032200|interpro:IPR032201|interpro:IPR038006|interpro:IPR038173|rcsb pdb:3LYR|rcsb pdb:3MQI|reactome:R-HSA-381340	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:iQ34gzH8tNLs6w0TO9aMwZ85M509606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:54D1359F1ED8CAFD|rigid:YMtPQfs1D/oMDXvJXVo7GowS6Wg	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P55060	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577164|imex:IM-24624-136	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	intact-crc:AF6BD8EEE93D6D04|rigid:7uXDPgxau5aj6kQ9R1WOBgtU00Q	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9Y6N1	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-2963275|uniprotkb:I3L220|ensembl:ENSP00000299335|ensembl:ENSP00000459901|uniprotkb:Q6FHB7|uniprotkb:Q9BRX0|uniprotkb:Q9UME8|uniprotkb:D3DTY5	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:cox11_human(display_long)|uniprotkb:COX11(gene name)|psi-mi:COX11(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577155|imex:IM-24624-135	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000166260(gene)|ensembl:ENST00000299335(transcript)|ensembl:ENST00000576370(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0009055"(electron transfer activity)|go:"GO:0031304"(intrinsic component of mitochondrial inner membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0055065"(metal ion homeostasis)|interpro:IPR007533(Cytochrome c oxidase assembly protein CtaG/Cox11)|interpro:IPR023471|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|refseq:NP_004366.1|refseq:XP_011522644.1|refseq:XP_016879681.1|refseq:XP_016879682.1|refseq:XP_016879683.1|refseq:XP_016879684.1|refseq:XP_016879685.1	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:inklcaALt6Jb0Cs/4ckzcG6YrHA9606	intact-crc:D66FD1860C026EA1|rigid:79W84QxtQ4LBNwFkx2tUDWpV+M0	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TEX9	uniprotkb:P49286	intact:EBI-395967|uniprotkb:Q2NL96|uniprotkb:Q86TZ9|uniprotkb:Q8NCG8|uniprotkb:Q96SJ3|uniprotkb:Q9BTI4|uniprotkb:Q9H5L0|uniprotkb:B2RN95|ensembl:ENSP00000346453|ensembl:ENSP00000494795	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:ipo4_human(display_long)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577200|imex:IM-24624-140	author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078934.3|dip:DIP-32944N|ensembl:ENSG00000196497(gene)|ensembl:ENSG00000285248(gene)|ensembl:ENST00000354464(transcript)|ensembl:ENST00000644546(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|interpro:IPR040122|mint:Q8TEX9|rcsb pdb:5XAH|rcsb pdb:5XBK	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:EBF8717380867434|rigid:t/bsiOluzEqQelOw2IbvwrZyXGs	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P30101	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577191|imex:IM-24624-139	author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|interpro:IPR017937|ensembl:ENSG00000167004(gene)|ensembl:ENST00000300289(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005304.3|dip:DIP-29132N	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606	intact-crc:FEF86C9FA7CD6774|rigid:dqrcuWi9uxVn6E/iLGRrROp73CY	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P02792	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-713279|uniprotkb:Q7Z2W1|uniprotkb:Q9BTZ8|ensembl:ENSP00000366525|uniprotkb:B2R4B9|uniprotkb:Q6IBT7|uniprotkb:Q86WI9|uniprotkb:Q8WU07|uniprotkb:Q96AU9|uniprotkb:Q96CU0	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:fril_human(display_long)|uniprotkb:FTL(gene name)|psi-mi:FTL(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577182|imex:IM-24624-138	author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_000137.2|ensembl:ENSG00000087086(gene)|ensembl:ENST00000331825(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0044754"(autolysosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|mint:P02792|rcsb pdb:2FFX|rcsb pdb:2FG4|rcsb pdb:2FG8|rcsb pdb:3KXU|rcsb pdb:4V6B|rcsb pdb:5LG8|rcsb pdb:6TR9|rcsb pdb:6TS0|rcsb pdb:6TS1|rcsb pdb:6TSA|rcsb pdb:6TSF|rcsb pdb:6TSJ|rcsb pdb:6WX6|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-31248N	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:+mbnoETQ9TuBZg8Gc09nwAjwKTE9606	intact-crc:29B201530F2EE9E9|rigid:SVtNYiEbvhRGB7JSPKqRe0SMxjE	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9HB75	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-520427|ensembl:ENSP00000337797|uniprotkb:Q59FD1|uniprotkb:Q59H10|uniprotkb:Q59HC7|uniprotkb:Q7Z4P8|uniprotkb:Q8NC89|uniprotkb:Q8NDL2|uniprotkb:Q96C25|uniprotkb:Q9NRE6	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:pidd1_human(display_long)|uniprotkb:PIDD1(gene name)|psi-mi:PIDD1(display_short)|uniprotkb:LRDD(gene name synonym)|uniprotkb:Leucine-rich repeat and death domain-containing protein(gene name synonym)|uniprotkb:PIDD(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577227|imex:IM-24624-143	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_665893.2|refseq:NP_665894.2|ensembl:ENSG00000177595(gene)|ensembl:ENST00000347755(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:XP_011518512.1|refseq:XP_011518513.1|refseq:XP_016873482.1|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR011029(DEATH-like)|interpro:IPR019502|interpro:IPR032675|mint:Q9HB75|rcsb pdb:2OF5|reactome:R-HSA-6803207	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:n0LSBUZQ057RjeGw0h+yCoXgi0w9606	intact-crc:0AA09077DBF27537|rigid:Fl0wdPz2S/G/NkIw0OcEMlvQ6GQ	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9P2N2	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-6872973|uniprotkb:Q9NW53|uniprotkb:Q8N4T3|uniprotkb:A8MQB7|uniprotkb:Q6P160|uniprotkb:A8MU88|ensembl:ENSP00000372964	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:rhg28_human(display_long)|uniprotkb:KIAA1314(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 28(gene name synonym)|uniprotkb:ARHGAP28(gene name)|psi-mi:ARHGAP28(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577218|imex:IM-24624-142	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000088756(gene)|ensembl:ENST00000383472(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1904425"(negative regulation of GTP binding)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-HSA-8980692	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:IYjZs2zg7OOFy5/mco/EhjGw1lE9606	intact-crc:F42E603884B88784|rigid:3heBLrpNQsM6V/YuTE6uWDSjVRc	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14573	uniprotkb:P49286	intact:EBI-351055|uniprotkb:Q14649|uniprotkb:Q5TAQ2|intact:EBI-28978202|ensembl:ENSP00000363435|ensembl:ENSP00000475177	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:itpr3_human(display_long)|uniprotkb:ITPR3(gene name)|psi-mi:ITPR3(display_short)|uniprotkb:Type 3 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 3(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577209|imex:IM-24624-141	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002215.2|ensembl:ENSP00000363435|ensembl:ENSP00000475177|ensembl:ENSG00000096433(gene)|ensembl:ENST00000374316(transcript)|ensembl:ENST00000605930(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043235"(receptor complex)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:Q14573|rcsb pdb:6DQJ|rcsb pdb:6DQN|rcsb pdb:6DQS|rcsb pdb:6DQV|rcsb pdb:6DQZ|rcsb pdb:6DR0|rcsb pdb:6DR2|rcsb pdb:6DRA|rcsb pdb:6DRC|rcsb pdb:6UQK|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|go:"GO:0007613"(memory)|reactome:R-HSA-983695	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:O+1OC4E0IrAOt+D672eXnhWHy3I9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:F4C00E8DBA388FBC|rigid:E8oUM/E9QGyRcci7eIUDsNrlNC8	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07960	uniprotkb:P49286	intact:EBI-602762|uniprotkb:D3DQQ6|ensembl:ENSP00000310491	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:rhg01_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym)|uniprotkb:Rho-related small GTPase protein activator(gene name synonym)|uniprotkb:p50-RhoGAP(gene name synonym)|uniprotkb:CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP1(gene name)|psi-mi:ARHGAP1(display_short)|uniprotkb:CDC42GAP(gene name synonym)|uniprotkb:RHOGAP1(gene name synonym)|uniprotkb:GTPase-activating protein rhoGAP(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577254|imex:IM-24624-146	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004299.1|refseq:XP_011518397.1|dip:DIP-6081N|ensembl:ENSG00000175220(gene)|ensembl:ENST00000311956(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|mint:Q07960|rcsb pdb:1AM4|rcsb pdb:1GRN|rcsb pdb:1OW3|rcsb pdb:1RGP|rcsb pdb:1TX4|rcsb pdb:2NGR|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:6R3V|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696270	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:ceA3oLsnddhLiSbylS89P64mYBo9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:0611F1C68F69BE81|rigid:n9af8ruyulGbj4xqC+1hTqzX56s	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UPM8	uniprotkb:P49286	intact:EBI-1222435|uniprotkb:A0AVD6|uniprotkb:Q9Y588|uniprotkb:A1L4A9|uniprotkb:A6NNX7|uniprotkb:H0YKX4|uniprotkb:Q68D31|ensembl:ENSP00000261842	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:ap4e1_human(display_long)|uniprotkb:AP4E1(gene name)|psi-mi:AP4E1(display_short)|uniprotkb:Epsilon subunit of AP-4(gene name synonym)|uniprotkb:Epsilon-adaptin(gene name synonym)|uniprotkb:AP-4 adaptor complex subunit epsilon(gene name synonym)|uniprotkb:Adaptor-related protein complex 4 subunit epsilon-1(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577245|imex:IM-24624-145	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006720510.1|refseq:NP_001239056.1|refseq:NP_031373.2|refseq:XP_005254321.1|ensembl:ENSG00000081014(gene)|ensembl:ENST00000261842(transcript)|go:"GO:0006605"(protein targeting)|go:"GO:0008104"(protein localization)|go:"GO:0030124"(AP-4 adaptor complex)|go:"GO:0031904"(endosome lumen)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017109(Adaptor protein complex AP-4, epsilon subunit)|interpro:IPR028269|reactome:R-HSA-432720|reactome:R-HSA-432722|go:"GO:0006898"(receptor-mediated endocytosis)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:LH5Dkp+lq2AmsH9eAUB2YwEkuh89606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:FCBDA9ECD684777F|rigid:lmt0OJdklY75UapGb32W/mK1XWE	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08253	uniprotkb:P49286	intact:EBI-1033518|uniprotkb:B2R6U1|uniprotkb:Q9UCJ8|ensembl:ENSP00000219070|uniprotkb:E9PE45|uniprotkb:B4DWH3	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:mmp2_human(display_long)|uniprotkb:MMP2(gene name)|psi-mi:MMP2(display_short)|uniprotkb:CLG4A(gene name synonym)|uniprotkb:72 kDa gelatinase(gene name synonym)|uniprotkb:Matrix metalloproteinase-2(gene name synonym)|uniprotkb:Gelatinase A(gene name synonym)|uniprotkb:TBE-1(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577236|imex:IM-24624-144	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001289437.1|refseq:NP_001289438.1|refseq:NP_001289439.1|ensembl:ENSG00000087245(gene)|ensembl:ENST00000219070(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001955"(blood vessel maturation)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007566"(embryo implantation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030017"(sarcomere)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048771"(tissue remodeling)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071492"(cellular response to UV-A)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000585(Hemopexin)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR002477(Peptidoglycan binding-like)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR024079|interpro:IPR028708|interpro:IPR033739|interpro:IPR036365|interpro:IPR036375|interpro:IPR036943|rcsb pdb:1CK7|rcsb pdb:1CXW|rcsb pdb:1EAK|rcsb pdb:1GEN|rcsb pdb:1GXD|rcsb pdb:1HOV|rcsb pdb:1J7M|rcsb pdb:1KS0|rcsb pdb:1QIB|rcsb pdb:1RTG|rcsb pdb:3AYU|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-381426|reactome:R-HSA-3928665|reactome:R-HSA-6785807|reactome:R-HSA-9009391|refseq:NP_001121363.1|refseq:NP_004521.1	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:s0IHoSkzT9GNfkkLZsVsV7cIf1g9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:9A2A8B665A7BBCDC|rigid:UhciKqQqAQpWrIWL4IlaZ/IVzpo	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:O95980	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-2823742|uniprotkb:Q8WX37|uniprotkb:Q5W0K6|uniprotkb:B2RNS1|ensembl:ENSP00000367202	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:reck_human(display_long)|uniprotkb:RECK(gene name)|psi-mi:RECK(display_short)|uniprotkb:ST15(gene name synonym)|uniprotkb:Suppressor of tumorigenicity 15 protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577272|imex:IM-24624-148	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	go:"GO:0030198"(extracellular matrix organization)|refseq:NP_066934.1|ensembl:ENSG00000122707(gene)|ensembl:ENST00000377966(transcript)|go:"GO:0001955"(blood vessel maturation)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007566"(embryo implantation)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0016020"(membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904684"(negative regulation of metalloendopeptidase activity)|go:"GO:1904928"(coreceptor activity involved in canonical Wnt signaling pathway)|go:"GO:1990909"(Wnt signalosome)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR036058|interpro:IPR039016|reactome:R-HSA-163125	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:u5Inim/c34NpYDTsW1DVOLJPDeA9606	intact-crc:BB25D897D370D1CE|rigid:RbIWoG9OY1Mzz0pUf5QDIUGV2x0	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P36956	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-948313|ensembl:ENSP00000261646|uniprotkb:Q59F52|uniprotkb:Q6P4R7|uniprotkb:Q6PFW7|uniprotkb:Q6PJ36|uniprotkb:Q8TAK9|uniprotkb:Q16062|uniprotkb:D3DXC4|uniprotkb:B0I4X3|uniprotkb:B0I4X4	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:srbp1_human(display_long)|uniprotkb:Sterol regulatory element-binding transcription factor 1(gene name synonym)|uniprotkb:SREBF1(gene name)|psi-mi:SREBF1(display_short)|uniprotkb:SREBP1(gene name synonym)|uniprotkb:BHLHD1(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577281|imex:IM-24624-149	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000072310(gene)|ensembl:ENST00000261646(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003062"(regulation of heart rate by chemical signal)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009749"(response to glucose)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010876"(lipid localization)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032094"(response to food)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033762"(response to glucagon)|go:"GO:0042493"|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1AM9|reactome:R-HSA-1368082|reactome:R-HSA-1655829|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-9029558|reactome:R-HSA-9615017|reactome:R-HSA-2426168|refseq:NP_001005291.1|refseq:NP_004167.3|dip:DIP-331N	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:DSEc6ZiI2ObB8g6FNEY9EGC+rps9606	intact-crc:95BF9BF6835F2F7F|rigid:ak1moZ2g8Y2y4p6sbxkUSYdgcE8	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14209	uniprotkb:P49286	intact:EBI-748547|uniprotkb:O00518|uniprotkb:Q6ICV7|uniprotkb:A6NIW1|ensembl:ENSP00000370588	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:cd99_human(display_long)|uniprotkb:T-cell surface glycoprotein E2(gene name synonym)|uniprotkb:E2 antigen(gene name synonym)|uniprotkb:Protein MIC2(gene name synonym)|uniprotkb:12E7(gene name synonym)|uniprotkb:CD99(gene name)|psi-mi:CD99(display_short)|uniprotkb:MIC2(gene name synonym)|uniprotkb:MIC2X(gene name synonym)|uniprotkb:MIC2Y(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577263|imex:IM-24624-147	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001116370.1|refseq:NP_002405.1|refseq:NP_001308296.1|refseq:NP_001308297.1|refseq:NP_001308298.1|ensembl:ENSG00000002586(gene)|ensembl:ENST00000381192(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0072683"(T cell extravasation)|go:"GO:2000391"(positive regulation of neutrophil extravasation)|interpro:IPR022078|reactome:R-HSA-198933|reactome:R-HSA-202733	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:g0uUrvPtgp5eBwP7RXnQa0Ij6GU9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:1D9895ED7F2EEA5C|rigid:Hc7oK2Oc1upDcW0upLRjAYhRpHU	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q14669	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-308443|uniprotkb:Q15644|ensembl:ENSP00000283943|uniprotkb:D4HL82|uniprotkb:Q14CA3|uniprotkb:Q14CF1|uniprotkb:Q53R87|uniprotkb:Q53TE7	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:tripc_human(display_long)|uniprotkb:TRIP12(gene name)|psi-mi:TRIP12(display_short)|uniprotkb:Thyroid receptor-interacting protein 12(gene name synonym)|uniprotkb:KIAA0045(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase for Arf(gene name synonym)|uniprotkb:ULF(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase TRIP12(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577308|imex:IM-24624-152	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_004229.1|refseq:NP_001271143.1|refseq:NP_001271144.1|refseq:NP_001271145.1|ensembl:ENSG00000153827(gene)|ensembl:ENST00000283943(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016607"(nuclear speck)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|interpro:IPR037197|mint:Q14669|reactome:R-HSA-983168|refseq:NP_001335244.1|refseq:NP_001335245.1|ensembl:ENSP00000283943|ensembl:ENST00000389044|ensembl:ENST00000389045|ensembl:ENSP00000373697|ensembl:ENSP00000373696|dip:DIP-58584N	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:294A7C063A3332DE	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:wzXMKIUEDV4y7YE6PDU+LIPHl7U9606	intact-crc:BFA8BBCA059F6434|rigid:InJA3iWiHPzYsOVVFUN6tCvvV3w	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0B7	uniprotkb:P49286	intact:EBI-311400|uniprotkb:Q569F9|uniprotkb:Q9H9K1|ensembl:ENSP00000261778	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:tng6_human(display_long)|uniprotkb:TANGO6(gene name)|psi-mi:TANGO6(display_short)|uniprotkb:KIAA1746(gene name synonym)|uniprotkb:TMCO7(gene name synonym)|uniprotkb:Transmembrane and coiled-coil domain-containing protein 7(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577299|imex:IM-24624-151	author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078838.1|interpro:IPR019451|ensembl:ENSG00000103047(gene)|ensembl:ENST00000261778(transcript)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019414|interpro:IPR039600	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:Rk5OHvOt9xLAiALMXDEBoaPTquE9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:E22392B07165B688|rigid:qjYg3FQZbjT+CjsW0u5v1/YVyK4	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BTW9	uniprotkb:P49286	intact:EBI-356005|uniprotkb:O95458|uniprotkb:Q7L8K1|uniprotkb:Q8IXP6|uniprotkb:Q8NAX0|uniprotkb:Q8WYH4|uniprotkb:Q96E74|uniprotkb:Q9UF82|uniprotkb:Q9UG46|uniprotkb:Q9Y2J3|intact:EBI-2555162|intact:EBI-2562220|ensembl:ENSP00000347719	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:tbcd_human(display_long)|uniprotkb:TBCD(gene name)|psi-mi:TBCD(display_short)|uniprotkb:KIAA0988(gene name synonym)|uniprotkb:SSD1(gene name synonym)|uniprotkb:TFCD(gene name synonym)|uniprotkb:PP1096(orf name)|uniprotkb:Tubulin-folding cofactor D(gene name synonym)|uniprotkb:Beta-tubulin cofactor D(gene name synonym)|uniprotkb:SSD-1(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577290|imex:IM-24624-150	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005984.3|ensembl:ENSG00000141556(gene)|ensembl:ENST00000355528(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007023"(post-chaperonin tubulin folding pathway)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0051087"(chaperone binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022577|interpro:IPR033162|mint:Q9BTW9|reactome:R-HSA-389977	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:9idLpkQy9EORh88FUMLul3LU3Yg9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:0BDBBA928FDB2277|rigid:aLs2Bq3tWGK8NPgTCFfDdVDj5+w	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHD9	uniprotkb:P49286	intact:EBI-947187|uniprotkb:O94798|uniprotkb:Q9H3W6|uniprotkb:Q9HAZ4|uniprotkb:Q5D027|intact:EBI-28967571|ensembl:ENSP00000345195	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:ubql2_human(display_long)|uniprotkb:UBQLN2(gene name)|psi-mi:UBQLN2(display_short)|uniprotkb:PLIC2(gene name synonym)|uniprotkb:HRIHFB2157(orf name)|uniprotkb:N4BP4(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 2(gene name synonym)|uniprotkb:Ubiquitin-like product Chap1/Dsk2(gene name synonym)|uniprotkb:DSK2 homolog(gene name synonym)|uniprotkb:Chap1(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577326|imex:IM-24624-154	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000345195|refseq:NP_038472.2|dip:DIP-42116N|ensembl:ENSG00000188021(gene)|ensembl:ENST00000338222(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904021"(negative regulation of G protein-coupled receptor internalization)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028430|interpro:IPR029071|mint:Q9UHD9|rcsb pdb:1J8C|rcsb pdb:2NBV|rcsb pdb:6MUN|reactome:R-HSA-8856825	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:tElcz7gHFkKFVDTz3PXeNcaBP7U9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:8C4BFCC8AE961384|rigid:qSo8CcXkDEzrjJpE3uX78vIbTbo	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q5T4S7	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1995940|intact:EBI-1059327|uniprotkb:A8MPT2|uniprotkb:A8MQ33|uniprotkb:A8MQB1|uniprotkb:O60646|uniprotkb:O75050|uniprotkb:Q4QRK5|uniprotkb:Q5T4S8|uniprotkb:Q5T4S9|uniprotkb:Q5TBN8|uniprotkb:Q5TBP2|uniprotkb:Q6DKH8|uniprotkb:Q6P4A4|uniprotkb:Q7L8P7|uniprotkb:Q8IXJ4|uniprotkb:Q8TDN5|uniprotkb:Q8WV67|uniprotkb:Q9HA46|uniprotkb:Q9P2N9|uniprotkb:Q9UG82|ensembl:ENSP00000364403	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ubr4_human(display_long)|uniprotkb:UBR4(gene name)|psi-mi:UBR4(display_short)|uniprotkb:KIAA0462(gene name synonym)|uniprotkb:KIAA1307(gene name synonym)|uniprotkb:RBAF600(gene name synonym)|uniprotkb:ZUBR1(gene name synonym)|uniprotkb:N-recognin-4(gene name synonym)|uniprotkb:Zinc finger UBR1-type protein 1(gene name synonym)|uniprotkb:Retinoblastoma-associated factor of 600 kDa(gene name synonym)|uniprotkb:600 kDa retinoblastoma protein-associated factor(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577335|imex:IM-24624-155	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_065816.2|ensembl:ENST00000375218|ensembl:ENSP00000364403|ensembl:ENSP00000364366|ensembl:ENSG00000127481(gene)|ensembl:ENST00000375254(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025704|interpro:IPR036322|mint:Q5T4S7|reactome:R-HSA-6798695|reactome:R-HSA-983168	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:8Iown8oj965YAir+95+3om5+1YM9606	intact-crc:82D195A2F4925DC1|rigid:E7A3dtadBW4o5hEvIzoU2QQAScI	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q14157	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577317|imex:IM-24624-153	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606	intact-crc:E4DBB12D25789604|rigid:+gh08BO1f8HLXXxgRq52H/Am4Rs	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35221	uniprotkb:P49286	intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577353|imex:IM-24624-157	author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:5CC8D75E60D116B3|rigid:wY6dPtWHDGZcdQ7Fa/0EOCWbak0	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q70CQ2	uniprotkb:P49286	intact:EBI-6256020|uniprotkb:A8MWD0|uniprotkb:B3KWU9|uniprotkb:O60316|uniprotkb:O94834|uniprotkb:Q3B777|uniprotkb:Q6P6C9|uniprotkb:Q7L8P6|uniprotkb:Q8N3T9|uniprotkb:Q8TBW2|uniprotkb:Q9UGA1|ensembl:ENSP00000381577	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:ubp34_human(display_long)|uniprotkb:USP34(gene name)|psi-mi:USP34(display_short)|uniprotkb:KIAA0570(gene name synonym)|uniprotkb:KIAA0729(gene name synonym)|uniprotkb:Deubiquitinating enzyme 34(gene name synonym)|uniprotkb:Ubiquitin thioesterase 34(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 34(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577344|imex:IM-24624-156	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055524.3|ensembl:ENSG00000115464(gene)|ensembl:ENST00000398571(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR038765|mint:Q70CQ2|reactome:R-HSA-201681|reactome:R-HSA-5689880	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:ouPBRH6ndkATju67iwZYOl1wYWM9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:DEAA4ECA20147D07|rigid:KI5M0iPMd1mXTs8m/n5kShH+b78	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P78527	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577371|imex:IM-24624-159	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	intact-crc:DBC14946C9404E3D|rigid:vUNRitG1xPs25PC+SgiieBBOlZ8	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P48556	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-359304|uniprotkb:Q6P1L7|uniprotkb:B4DX18|ensembl:ENSP00000215071|ensembl:ENSP00000481136	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:psmd8_human(display_long)|uniprotkb:PSMD8(gene name)|psi-mi:PSMD8(display_short)|uniprotkb:26S proteasome regulatory subunit S14(gene name synonym)|uniprotkb:p31(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN12(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577380|imex:IM-24624-160	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_002803.2|ensembl:ENSG00000099341(gene)|ensembl:ENST00000215071(transcript)|ensembl:ENST00000620216(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|interpro:IPR033464|mint:P48556|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5M32|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-180534	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:73qmlkzCwdeHlNzUy7vy7qmIok09606	intact-crc:C612543B083299A4|rigid:g7PpIlUWn6J3YjpiDhBXNe0nquU	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y217	uniprotkb:P49286	intact:EBI-766064|uniprotkb:Q5JRG6|uniprotkb:Q86TB7|uniprotkb:Q86YH4|uniprotkb:Q96P80|uniprotkb:B2RBB5|uniprotkb:B3KSB4|ensembl:ENSP00000371221	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:mtmr6_human(display_long)|uniprotkb:MTMR6(gene name)|psi-mi:MTMR6(display_short)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577362|imex:IM-24624-158	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004676.3|ensembl:ENSG00000139505(gene)|ensembl:ENST00000381801(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0106018"(phosphatidylinositol-3,5-bisphosphate phosphatase activity)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR030564|interpro:IPR030581|interpro:IPR035998|mint:Q9Y217|rcsb pdb:2YF0|reactome:R-HSA-1660499	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:BElxBLRw8vrnpTuAJzkoWEtICVA9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:A1AF748B12800AE8|rigid:KEOGLhQByV7K1l9XThjfDRZqpHU	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NRR5	uniprotkb:P49286	intact:EBI-711226|intact:EBI-722657|uniprotkb:Q9BR98|uniprotkb:Q9UHX4|ensembl:ENSP00000357292|uniprotkb:Q5VYA1|uniprotkb:B2RAY7|uniprotkb:A6ND44|uniprotkb:Q5VYA0	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:ubql4_human(display_long)|uniprotkb:UBQLN4(gene name)|psi-mi:UBQLN4(display_short)|uniprotkb:C1orf6(gene name synonym)|uniprotkb:UBIN(gene name synonym)|uniprotkb:Ataxin-1 ubiquitin-like-interacting protein A1U(gene name synonym)|uniprotkb:Ataxin-1 interacting ubiquitin-like protein(gene name synonym)|uniprotkb:CIP75(gene name synonym)|uniprotkb:Connexin43-interacting protein of 75 kDa(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577398|imex:IM-24624-162	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291271.1|refseq:NP_064516.2|ensembl:ENSG00000160803(gene)|interpro:IPR029071|ensembl:ENST00000368309(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:H/kLIS8aSMue9jYu1Q4qTcBLt5o9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:35DED6B337AFFBE6|rigid:e6Z1jwpz6lNNM5kCwoVw5lEs+7U	false	-	sufficient binding region:133-160	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z460	uniprotkb:P49286	intact:EBI-913476|uniprotkb:B7ZLX3|uniprotkb:O75118|uniprotkb:Q2KHQ9|uniprotkb:Q5H9P0|uniprotkb:Q8N5B8|uniprotkb:Q9BQT5|ensembl:ENSP00000263710|intact:EBI-2562829|uniprotkb:A2RU21|uniprotkb:F5GWS0|intact:EBI-10967465	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:clap1_human(display_long)|uniprotkb:CLASP1(gene name)|psi-mi:CLASP1(display_short)|uniprotkb:KIAA0622(gene name synonym)|uniprotkb:MAST1(gene name synonym)|uniprotkb:Cytoplasmic linker-associated protein 1(gene name synonym)|uniprotkb:Multiple asters homolog 1(gene name synonym)|uniprotkb:Protein Orbit homolog 1(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577389|imex:IM-24624-161	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001135745.1|refseq:NP_001135746.1|refseq:NP_001193980.1|refseq:NP_056097.1|ensembl:ENSG00000074054(gene)|ensembl:ENST00000263710(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008017"(microtubule binding)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0016020"(membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031111"(negative regulation of microtubule polymerization or depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031592"(centrosomal corona)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045180"(basal cortex)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|refseq:XP_011509150.1|ensembl:ENSP00000263710|ensembl:ENST00000397587|ensembl:ENSP00000380717|ensembl:ENST00000409078|ensembl:ENSP00000386442|ensembl:ENST00000541377|ensembl:ENSP00000441625|interpro:IPR024395|interpro:IPR028399|interpro:IPR034085|rcsb pdb:4K92|rcsb pdb:6MQ5|rcsb pdb:6MQ7|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-428890|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:ZhVWdhW2ylZHeewHZ63lg5FQT1c9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:717A4091B62FFD03|rigid:mxEfG5rBzA83tSamMQr+VWWcqRg	false	-	sufficient binding region:133-160	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P32242	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-740446|uniprotkb:A6NHA2|uniprotkb:B3KTJ4|uniprotkb:Q53TG6|ensembl:ENSP00000282549|ensembl:ENSP00000355631	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:otx1_human(display_long)|uniprotkb:Orthodenticle homolog 1(gene name synonym)|uniprotkb:OTX1(gene name)|psi-mi:OTX1(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577407|imex:IM-24624-163	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001186699.1|refseq:NP_055377.1|ensembl:ENST00000282549(transcript)|ensembl:ENST00000366671(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048852"(diencephalon morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003025(Transcription factor Otx)|interpro:IPR003026(Transcription factor Otx1, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|ensembl:ENSG00000115507(gene)	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:yfHBcEcusuw0p6r/GOigJsQ2KK09606	intact-crc:C0548C5D83161651|rigid:MNBnD7AT/c9Xua/A0Aa6r/SNPps	false	sufficient binding region:133-160	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14674	uniprotkb:P49286	intact:EBI-2554882|intact:EBI-28978215|ensembl:ENSP00000257934	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:espl1_human(display_long)|uniprotkb:ESP1(gene name synonym)|uniprotkb:KIAA0165(gene name synonym)|uniprotkb:Separase(gene name synonym)|uniprotkb:Caspase-like protein ESPL1(gene name synonym)|uniprotkb:Extra spindle poles-like 1 protein(gene name synonym)|uniprotkb:ESPL1(gene name)|psi-mi:ESPL1(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577425|imex:IM-24624-165	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036423.4|refseq:XP_011537326.1|ensembl:ENSP00000257934|refseq:XP_006719768.1|refseq:XP_016875742.1|dip:DIP-46079N|ensembl:ENST00000257934(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003824"(catalytic activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|reactome:R-HSA-2467813|ensembl:ENSG00000135476(gene)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:oK4Wg46DenILU6xADFkxkybkOcI9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:7AB15746A037390D|rigid:gEjAOh853nh4Mai7kv83ibenG6U	false	-	sufficient binding region:133-160	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13618	uniprotkb:P49286	intact:EBI-456129|uniprotkb:O75415|uniprotkb:Q569L3|uniprotkb:Q9UBI8|uniprotkb:B8ZZC3|uniprotkb:Q9UET7|uniprotkb:A8K536|ensembl:ENSP00000264414	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:cul3_human(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:KIAA0617(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577416|imex:IM-24624-164	author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003581.1|refseq:NP_001244126.1|refseq:NP_001244127.1|dip:DIP-31611N|ensembl:ENSG00000036257(gene)|ensembl:ENST00000264414(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000922"(spindle pole)|go:"GO:0001831"(trophectodermal cellular morphogenesis)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017145"(stem cell division)|go:"GO:0030030"(cell projection organization)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072576"(liver morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13618|rcsb pdb:2MYL|rcsb pdb:2MYM|rcsb pdb:4AP2|rcsb pdb:4APF|rcsb pdb:4EOZ|rcsb pdb:4HXI|rcsb pdb:5NLB|rcsb pdb:6I2M|reactome:R-HSA-4641258|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9706019|reactome:R-HSA-983168	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:xI/8pHB9nckOW629STOqKba4KzQ9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:922E5AF714C3A59D|rigid:Yx2Z+3gt2OaOP7vFZzFqrpSXDsc	false	-	sufficient binding region:133-160	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P63092	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1047114|uniprotkb:P04895|uniprotkb:Q12927|uniprotkb:Q5JWD2|uniprotkb:Q5JWD4|uniprotkb:Q5JWD5|uniprotkb:Q6NR75|uniprotkb:Q6NXS0|uniprotkb:Q8TBC0|uniprotkb:Q96H70|uniprotkb:Q14433|uniprotkb:Q32P26|uniprotkb:E1P5G5|ensembl:ENSP00000360126|uniprotkb:A6NI00|intact:EBI-10977858	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:gnas2_human(display_long)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:GNAS1(gene name synonym)|uniprotkb:GSP(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577434|imex:IM-24624-166	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001070958.1|refseq:NP_001296769.1|refseq:NP_536350.2|refseq:NP_000507.1|refseq:NP_001070956.1|refseq:NP_001070957.1|ensembl:ENSG00000087460(gene)|ensembl:ENST00000371085(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0048589"(developmental growth)|go:"GO:0050890"(cognition)|go:"GO:0060348"(bone development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63092|rcsb pdb:5G53|rcsb pdb:5UZ7|rcsb pdb:5VAI|rcsb pdb:6AU6|rcsb pdb:6B3J|rcsb pdb:6E3Y|rcsb pdb:6E67|rcsb pdb:6EG8|rcsb pdb:6GDG|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LPB|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6ORV|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VN7|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XOX|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7BPH|rcsb pdb:7BW0|rcsb pdb:7BZ2|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX3|rcsb pdb:7CX4|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7D7M|rcsb pdb:7DHI|rcsb pdb:7DHR|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7KH0|rcsb pdb:7LCI|rcsb pdb:7LJC|rcsb pdb:7LJD|rcsb pdb:7MBX|reactome:R-HSA-163359|reactome:R-HSA-164378|reactome:R-HSA-381676|reactome:R-HSA-392851|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-432040|reactome:R-HSA-5610787|reactome:R-HSA-9660821|refseq:NP_536351.1	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:fUnrdxwx4bBAqE3iO2cCB3UInyg9606	intact-crc:9EEE8DAA93072610|rigid:LM3HaC/TSWoRYzwN8Xzr/C8xGeI	false	sufficient binding region:133-160	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14669	uniprotkb:P49286	intact:EBI-308443|uniprotkb:Q15644|ensembl:ENSP00000283943|uniprotkb:D4HL82|uniprotkb:Q14CA3|uniprotkb:Q14CF1|uniprotkb:Q53R87|uniprotkb:Q53TE7	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:tripc_human(display_long)|uniprotkb:TRIP12(gene name)|psi-mi:TRIP12(display_short)|uniprotkb:Thyroid receptor-interacting protein 12(gene name synonym)|uniprotkb:KIAA0045(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase for Arf(gene name synonym)|uniprotkb:ULF(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase TRIP12(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577443|imex:IM-24624-167	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004229.1|refseq:NP_001271143.1|refseq:NP_001271144.1|refseq:NP_001271145.1|ensembl:ENSG00000153827(gene)|ensembl:ENST00000283943(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016607"(nuclear speck)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|interpro:IPR037197|mint:Q14669|reactome:R-HSA-983168|refseq:NP_001335244.1|refseq:NP_001335245.1|ensembl:ENSP00000283943|ensembl:ENST00000389044|ensembl:ENST00000389045|ensembl:ENSP00000373697|ensembl:ENSP00000373696|dip:DIP-58584N	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	caution:This sequence has been withdrawn from Uniprot.|crc64:294A7C063A3332DE	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:wzXMKIUEDV4y7YE6PDU+LIPHl7U9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:D8FAD92C75008B43|rigid:InJA3iWiHPzYsOVVFUN6tCvvV3w	false	-	sufficient binding region:133-160	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q12874	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1051880|uniprotkb:Q15460|uniprotkb:Q5VT87|uniprotkb:D3DPT5|ensembl:ENSP00000362110	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:sf3a3_human(display_long)|uniprotkb:Spliceosome-associated protein 61(gene name synonym)|uniprotkb:SF3a60(gene name synonym)|uniprotkb:SF3A3(gene name)|psi-mi:SF3A3(display_short)|uniprotkb:SAP61(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577452|imex:IM-24624-168	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_006793.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR021966|interpro:IPR024598|interpro:IPR031774|interpro:IPR031776|mint:Q12874|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|go:"GO:0000389"(mRNA 3'-splice site recognition)|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163|rcsb pdb:6Y53|ensembl:ENSG00000183431(gene)|ensembl:ENST00000373019(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-882N	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:fNjNguUOXqApr46rOAEpTs2geqY9606	intact-crc:FC599134566F7DC7|rigid:Pw1nwJA89tEMokW0GWO0TKD4Spc	false	sufficient binding region:133-160	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BXK5	uniprotkb:P49286	intact:EBI-747430|uniprotkb:Q96B37|uniprotkb:Q96IB7|uniprotkb:Q9BY01|uniprotkb:Q9HC05|uniprotkb:Q9UFE0|uniprotkb:Q9UKN3|ensembl:ENSP00000318883|uniprotkb:B3KPE7	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:b2l13_human(display_long)|uniprotkb:Protein Mil1(gene name synonym)|uniprotkb:Bcl-rambo(gene name synonym)|uniprotkb:BCL2L13(gene name)|psi-mi:BCL2L13(display_short)|uniprotkb:MIL1(gene name synonym)|uniprotkb:CD003(orf name)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577479|imex:IM-24624-171	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056182.2|refseq:XP_011544423.1|ensembl:ENSG00000099968(gene)|ensembl:ENST00000317582(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR026298|interpro:IPR036834|interpro:IPR042398|rcsb pdb:2IPD|dip:DIP-60895N|refseq:NP_001257658.1|refseq:NP_001257659.1|refseq:NP_001257660.1|refseq:XP_016884217.1|refseq:XP_016884218.1|refseq:XP_016884219.1|refseq:XP_016884220.1|refseq:XP_016884221.1|refseq:XP_016884222.1	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:CTVG9Xyunw/XyOeGX4zYaSXdo6Y9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:043C895B2B0F27B0|rigid:sdwzUMUHXg4LvgNabwgkV/5XeWk	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y490	uniprotkb:P49286	intact:EBI-2462036|uniprotkb:A6NMY0|uniprotkb:Q86YD0|uniprotkb:Q9NZQ2|uniprotkb:Q9UHH8|uniprotkb:Q9UPX3|intact:EBI-28967697|ensembl:ENSP00000316029	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:tln1_human(display_long)|uniprotkb:TLN1(gene name)|psi-mi:TLN1(display_short)|uniprotkb:KIAA1027(gene name synonym)|uniprotkb:TLN(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577461|imex:IM-24624-169	author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000316029|refseq:NP_006280.3|ensembl:ENSG00000137076(gene)|ensembl:ENST00000314888(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0017166"(vinculin binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033622"(integrin activation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036476|interpro:IPR036723|interpro:IPR037438|mint:Q9Y490|rcsb pdb:1SYQ|rcsb pdb:2MWN|rcsb pdb:4DJ9|rcsb pdb:6R9T|reactome:R-HSA-114608|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381038|reactome:R-HSA-399955|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:C7FGaR2291KB6hBSloee5L8lYgA9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:04E24893E5DCC017|rigid:nsE+/vtCQ/8A5HxsjIcd1BI0gsU	false	-	sufficient binding region:133-160	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z4K8	uniprotkb:P49286	intact:EBI-723344|uniprotkb:Q6NT17|uniprotkb:Q6NT41|uniprotkb:Q6ZRL7|uniprotkb:Q9H5P2|ensembl:ENSP00000334657|uniprotkb:A0AVI6|uniprotkb:Q5VT60|uniprotkb:Q5VT62|uniprotkb:B1AVQ4	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:tri46_human(display_long)|uniprotkb:Tripartite, fibronectin type-III and C-terminal SPRY motif protein(gene name synonym)|uniprotkb:Gene Y protein(gene name synonym)|uniprotkb:TRIM46(gene name)|psi-mi:TRIM46(display_short)|uniprotkb:TRIFIC(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577470|imex:IM-24624-170	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079334.3|ensembl:ENSG00000163462(gene)|ensembl:ENST00000334634(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001764"(neuron migration)|interpro:IPR027370|interpro:IPR035731|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|reactome:R-HSA-877300|go:"GO:0005856"(cytoskeleton)|go:"GO:0007409"(axonogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0043194"(axon initial segment)|go:"GO:0044304"(main axon)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0099612"(protein localization to axon)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|go:"GO:1903827"|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990769"(proximal neuron projection)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|refseq:NP_001243528.1|refseq:NP_001243529.1|refseq:NP_001243530.1|refseq:NP_001269307.1|refseq:NP_001269308.1	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:Te5aeDC5aMKYNhajjekIRJCtzBQ9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:78EF13C7F2D4E6D4|rigid:NoDttOM9lqdatR1u1sefr0gdE44	false	-	sufficient binding region:133-160	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P55283	uniprotkb:P49286	intact:EBI-7962551|uniprotkb:Q5VZ44|uniprotkb:B3KWB8|intact:UNK-5840827|uniprotkb:Q9BZ05|uniprotkb:G3V1P8|uniprotkb:Q2M208|intact:EBI-28987053|ensembl:ENSP00000484928	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:cadh4_human(display_long)|uniprotkb:CDH4(gene name)|psi-mi:CDH4(display_short)|uniprotkb:Retinal cadherin(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577506|imex:IM-24624-174	author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000543233|ensembl:ENSP00000443301|ensembl:ENSP00000484928|refseq:NP_001785.2|refseq:NP_001239268.1|ensembl:ENSG00000179242(gene)|ensembl:ENST00000614565(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0016342"(catenin complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|reactome:R-HSA-418990|reactome:R-HSA-525793	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May play an important role in retinal development|comment:mint	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:OIKZS03I/77zy4/8aTb8hA4ou8s9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:16F57842F8E53591|rigid:e490euafrVTjAPI14i1t0soNHFc	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P55290	uniprotkb:P49286	intact:EBI-7205595|uniprotkb:B7Z590|uniprotkb:C9JRI6|uniprotkb:J3KN62|uniprotkb:A8W476|uniprotkb:Q6GTW4|uniprotkb:Q8TBX3|intact:MINT-7004770|uniprotkb:A8W477|ensembl:ENSP00000479395	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:cad13_human(display_long)|uniprotkb:CDH13(gene name)|psi-mi:CDH13(display_short)|uniprotkb:CDHH(gene name synonym)|uniprotkb:Truncated cadherin(gene name synonym)|uniprotkb:Heart cadherin(gene name synonym)|uniprotkb:P105(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577497|imex:IM-24624-173	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001207418.1|refseq:NP_001207420.1|refseq:NP_001248.1|refseq:NP_001207421.1|ensembl:ENSG00000140945(gene)|ensembl:ENST00000567109(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051668"(localization within membrane)|go:"GO:0055096"(low-density lipoprotein particle mediated signaling)|go:"GO:0055100"(adiponectin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098982"(GABA-ergic synapse)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR033216|interpro:IPR039808|rcsb pdb:2V37|reactome:R-HSA-418990|go:"GO:0030169"(low-density lipoprotein particle binding)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth|comment:mint|comment:homomint	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:A/yGuBo0kdt3n1VXD59yhikx3g49606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:738DD5B73FA488BA|rigid:4D5JAAHprgx0hkSjjcpC9OSwiA4	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13042	uniprotkb:P49286	intact:EBI-994830|uniprotkb:Q96AE6|uniprotkb:Q9Y564|uniprotkb:A2A365|uniprotkb:Q5T8C8|ensembl:ENSP00000348554|ensembl:ENSP00000353549|uniprotkb:Q7Z651	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:cdc16_human(display_long)|uniprotkb:ANAPC6(gene name synonym)|uniprotkb:CDC16 homolog(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 6(gene name synonym)|uniprotkb:Cyclosome subunit 6(gene name synonym)|uniprotkb:CDC16(gene name)|psi-mi:CDC16(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577488|imex:IM-24624-172	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001072113.1|refseq:NP_003894.3|reactome:R-HSA-2559582|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|rcsb pdb:5L9T|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|rcsb pdb:5L9U|go:"GO:0016567"(protein ubiquitination)|rcsb pdb:5LCW|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0072686"(mitotic spindle)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:6Q6G|interpro:IPR019734|rcsb pdb:3HYM|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:4UI9|rcsb pdb:6TNT|reactome:R-HSA-141430|rcsb pdb:5A31|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|reactome:R-HSA-69017|reactome:R-HSA-2467813|reactome:R-HSA-179409|ensembl:ENSG00000130177(gene)|ensembl:ENST00000356221(transcript)|ensembl:ENST00000360383(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|refseq:NP_001305446.1|refseq:NP_001305447.1|refseq:NP_001317030.1|refseq:NP_001317033.1|refseq:NP_001317034.1|refseq:XP_016876322.1|dip:DIP-36423N	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:AAG0s18JHrn+M5dG7T/N6t0Y97w9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:2241EB83F65D275B|rigid:8SiJoIIyZ8oSCVcVflJ4aGVthSU	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P55060	uniprotkb:P49286	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577515|imex:IM-24624-175	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:AA8B806684B146C8|rigid:7uXDPgxau5aj6kQ9R1WOBgtU00Q	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P55287	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1754095|uniprotkb:A8MZC8|uniprotkb:Q15065|uniprotkb:Q15066|uniprotkb:Q9UQ93|uniprotkb:Q9UQ94|uniprotkb:A8K5D6|uniprotkb:B7WP28|ensembl:ENSP00000268603	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:cad11_human(display_long)|uniprotkb:CDH11(gene name)|psi-mi:CDH11(display_short)|uniprotkb:Osteoblast cadherin(gene name synonym)|uniprotkb:OSF-4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577524|imex:IM-24624-176	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:XP_011521105.1|refseq:NP_001788.2|refseq:NP_001295321.1|ensembl:ENSG00000140937(gene)|ensembl:ENST00000268603(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0021957"(corticospinal tract morphogenesis)|go:"GO:0034332"(adherens junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|reactome:R-HSA-418990|refseq:XP_005255818.1|refseq:XP_005255819.1|refseq:XP_005255820.1	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:Q1WNdOFoMB2ItSXG55xVxGkQ+UM9606	intact-crc:BF8812262FAA5CD2|rigid:VDg3AQBKBJuHtl33S2m6RcIrtmU	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q03001	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577533|imex:IM-24624-177	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	intact-crc:740700C552A0585A|rigid:bgmiGAewunu0LkgY4LFtwlJt9kI	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q13618	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-456129|uniprotkb:O75415|uniprotkb:Q569L3|uniprotkb:Q9UBI8|uniprotkb:B8ZZC3|uniprotkb:Q9UET7|uniprotkb:A8K536|ensembl:ENSP00000264414	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:cul3_human(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:KIAA0617(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577560|imex:IM-24624-180	author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_003581.1|refseq:NP_001244126.1|refseq:NP_001244127.1|dip:DIP-31611N|ensembl:ENSG00000036257(gene)|ensembl:ENST00000264414(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000922"(spindle pole)|go:"GO:0001831"(trophectodermal cellular morphogenesis)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017145"(stem cell division)|go:"GO:0030030"(cell projection organization)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072576"(liver morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13618|rcsb pdb:2MYL|rcsb pdb:2MYM|rcsb pdb:4AP2|rcsb pdb:4APF|rcsb pdb:4EOZ|rcsb pdb:4HXI|rcsb pdb:5NLB|rcsb pdb:6I2M|reactome:R-HSA-4641258|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9706019|reactome:R-HSA-983168	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:xI/8pHB9nckOW629STOqKba4KzQ9606	intact-crc:F09C609909D06126|rigid:Yx2Z+3gt2OaOP7vFZzFqrpSXDsc	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9NVI1	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1013291|uniprotkb:Q96JN1|uniprotkb:Q96ST0|uniprotkb:Q9BT96|uniprotkb:A5YMH4|uniprotkb:A6NJZ0|uniprotkb:A4ZVE4|ensembl:ENSP00000310842	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:fanci_human(display_long)|uniprotkb:FANCI(gene name)|psi-mi:FANCI(display_short)|uniprotkb:KIAA1794(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577551|imex:IM-24624-179	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:XP_011520058.1|refseq:XP_011520059.1|refseq:XP_011520066.1|refseq:NP_001106849.1|refseq:NP_060663.2|dip:DIP-29381N|ensembl:ENSG00000140525(gene)|ensembl:ENST00000310775(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR026171|interpro:IPR029305|interpro:IPR029308|interpro:IPR029310|interpro:IPR029312|interpro:IPR029313|interpro:IPR029314|interpro:IPR029315|mint:Q9NVI1|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|reactome:R-HSA-6783310|reactome:R-HSA-6796648	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:yJJMHIBOVPDIQcCBJ19DGitg3VA9606	intact-crc:E5FE1A3E763A5648|rigid:aFlRUh9JLzfntRR4QLQHhW0dkyE	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14152	uniprotkb:P49286	intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|ensembl:ENSP00000358140|ensembl:ENSP00000438178|uniprotkb:B4DYS1|uniprotkb:F5H335	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577542|imex:IM-24624-178	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003741.1|ensembl:ENSP00000358140|ensembl:ENSP00000438178|ensembl:ENSG00000107581(gene)|ensembl:ENST00000369144(transcript)|ensembl:ENST00000541549(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0006413"(translational initiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:D61CCD58AA680EDB|rigid:wr+eF/7TE1ym078l8D3M7xOJ9sM	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q07817	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-78035|intact:EBI-28978054|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|uniprotkb:Q5TE65|uniprotkb:Q92976|uniprotkb:Q5CZ89|uniprotkb:E1P5L6	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:b2cl1_human(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577578|imex:IM-24624-182	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001182.1|refseq:NP_612815.1|ensembl:ENSG00000171552(gene)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)|ensembl:ENST00000678563(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009566"(fertilization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034097"(response to cytokine)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071839"(apoptotic process in bone marrow cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR004725(Apoptosis regulator Bcl-X protein)|interpro:IPR013279(Apoptosis regulator, Bcl-X)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR020731|interpro:IPR026298|interpro:IPR036834|mint:Q07817|rcsb pdb:1BXL|rcsb pdb:1G5J|rcsb pdb:1LXL|rcsb pdb:1MAZ|rcsb pdb:1R2D|rcsb pdb:1R2E|rcsb pdb:1R2G|rcsb pdb:1R2H|rcsb pdb:1R2I|rcsb pdb:1YSG|rcsb pdb:1YSI|rcsb pdb:1YSN|rcsb pdb:2B48|rcsb pdb:2LP8|rcsb pdb:2LPC|rcsb pdb:2M03|rcsb pdb:2M04|rcsb pdb:2ME8|rcsb pdb:2ME9|rcsb pdb:2MEJ|rcsb pdb:2O1Y|rcsb pdb:2O2M|rcsb pdb:2O2N|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:2YJ1|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:2YXJ|rcsb pdb:3CVA|rcsb pdb:3FDL|rcsb pdb:3FDM|rcsb pdb:3INQ|rcsb pdb:3IO8|rcsb pdb:3PL7|rcsb pdb:3QKD|rcsb pdb:3R85|rcsb pdb:6IJQ|rcsb pdb:6LHD|rcsb pdb:6O0K|rcsb pdb:6O0L|rcsb pdb:6O0M|rcsb pdb:6O0O|rcsb pdb:6O0P|rcsb pdb:6RNU|rcsb pdb:6ST2|rcsb pdb:6UVC|rcsb pdb:6UVD|rcsb pdb:6UVE|rcsb pdb:6UVF|rcsb pdb:6UVG|rcsb pdb:6UVH|rcsb pdb:6VWC|rcsb pdb:6X7I|rcsb pdb:6YLI|rcsb pdb:6ZHC|rcsb pdb:7CA4|rcsb pdb:7JGV|rcsb pdb:7JGW|rcsb pdb:7LH7|reactome:R-HSA-111453|reactome:R-HSA-6785807|reactome:R-HSA-844455|reactome:R-HSA-9648002|reactome:R-HSA-9702518|rcsb pdb:3SP7|rcsb pdb:3SPF|rcsb pdb:3WIZ|rcsb pdb:3ZK6|rcsb pdb:3ZLN|rcsb pdb:6F46|rcsb pdb:6HJL|rcsb pdb:3ZLO|rcsb pdb:3ZLR|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4AQ3|rcsb pdb:4BPK|rcsb pdb:4C52|rcsb pdb:4C5D|rcsb pdb:4CIN|rcsb pdb:4EHR|rcsb pdb:4HNJ|rcsb pdb:4IEH|rcsb pdb:4PPI|rcsb pdb:4QVE|rcsb pdb:4QVF|rcsb pdb:4QVX|rcsb pdb:4TUH|rcsb pdb:4Z9V|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5B1Z|rcsb pdb:5C3G|rcsb pdb:5FMJ|rcsb pdb:5FMK|rcsb pdb:5VAY|rcsb pdb:5VX3|rcsb pdb:6BF2|rcsb pdb:6DCN|rcsb pdb:6DCO|ensembl:ENSP00000365223|ensembl:ENSP00000365230|ensembl:ENSP00000390760|ensembl:ENST00000376055|ensembl:ENST00000422920|ensembl:ENSP00000411252|ensembl:ENSP00000401173|ensembl:ENSP00000389688|ensembl:ENSP00000395545|ensembl:ENSP00000503725|ensembl:ENSP00000504536|ensembl:ENSP00000504387|ensembl:ENSP00000504237|ensembl:ENSP00000302564|refseq:NP_001304848.1|refseq:NP_001304849.1|refseq:NP_001304850.1|refseq:NP_001309168.1|refseq:NP_001309169.1|refseq:NP_001309171.1|refseq:XP_011527266.1|refseq:XP_016883482.1|dip:DIP-30916N	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606	intact-crc:EF263546FACE9C2B|rigid:YI7YUCoH2lb3+YKCRtXgE2Um+iU	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08133	uniprotkb:P49286	intact:EBI-352541|uniprotkb:B7Z8A7|uniprotkb:E9PGK1|uniprotkb:Q6ZT79|uniprotkb:D3DQH4|ensembl:ENSP00000346550	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:anxa6_human(display_long)|uniprotkb:ANXA6(gene name)|psi-mi:ANXA6(display_short)|uniprotkb:ANX6(gene name synonym)|uniprotkb:Annexin-6(gene name synonym)|uniprotkb:Annexin VI(gene name synonym)|uniprotkb:Lipocortin VI(gene name synonym)|uniprotkb:p68(gene name synonym)|uniprotkb:p70(gene name synonym)|uniprotkb:Protein III(gene name synonym)|uniprotkb:Chromobindin-20(gene name synonym)|uniprotkb:67 kDa calelectrin(gene name synonym)|uniprotkb:Calphobindin-II(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577569|imex:IM-24624-181	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001146.2|refseq:NP_001180473.1|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0008289"(lipid binding)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051283"(negative regulation of sequestering of calcium ion)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097190"(apoptotic signaling pathway)|ensembl:ENSG00000197043(gene)|ensembl:ENST00000354546(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003418"(growth plate cartilage chondrocyte differentiation)|interpro:IPR001464(Annexin)|interpro:IPR002393(Annexin, type VI)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|rcsb pdb:1M9I|reactome:R-HSA-445355	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:+1oKdgl2a0haedrMSJ8au35MF8c9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:3C5689D14EEE53E8|rigid:afYO5vadJW2LQQzlI0419GAISY0	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96P70	uniprotkb:P49286	intact:EBI-356319|intact:EBI-1059309|uniprotkb:Q8N1Y1|uniprotkb:Q8N3I2|uniprotkb:Q8NCG9|uniprotkb:Q96SU6|uniprotkb:Q9NW01|uniprotkb:Q9P0A8|uniprotkb:Q9ULM8|ensembl:ENSP00000354742|uniprotkb:B1ASV5	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:ipo9_human(display_long)|uniprotkb:HSPC273(orf name)|uniprotkb:IPO9(gene name)|psi-mi:IPO9(display_short)|uniprotkb:IMP9(gene name synonym)|uniprotkb:KIAA1192(gene name synonym)|uniprotkb:RANBP9(gene name synonym)|uniprotkb:Ran-binding protein 9(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577596|imex:IM-24624-184	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060555.2|ensembl:ENSG00000198700(gene)|ensembl:ENST00000361565(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|mint:Q96P70|rcsb pdb:6N1Z	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:jsjQSBULeF1L2FlDcPZouMz6pJE9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:DDE4669E453F9A49|rigid:VqjvoDdkfQ5OmRtePKtLUuLEADQ	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9ULT8	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-310559|uniprotkb:Q6P445|uniprotkb:Q86VJ1|uniprotkb:Q96F34|uniprotkb:Q9UFZ7|uniprotkb:D3DS86|ensembl:ENSP00000382269|ensembl:ENSP00000450697	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:hecd1_human(display_long)|uniprotkb:HECTD1(gene name)|psi-mi:HECTD1(display_short)|uniprotkb:KIAA1131(gene name synonym)|uniprotkb:HECT domain-containing protein 1(gene name synonym)|uniprotkb:E3 ligase for inhibin receptor(gene name synonym)|uniprotkb:EULIR(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase HECTD1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577587|imex:IM-24624-183	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000092148(gene)|ensembl:ENST00000399332(transcript)|ensembl:ENST00000553700(transcript)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001843"(neural tube closure)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035904"(aorta development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR000569(HECT)|interpro:IPR002110(Ankyrin)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010606(Mib-herc2)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020683|interpro:IPR035983|interpro:IPR036770|interpro:IPR037252|interpro:IPR041200|mint:Q9ULT8|rcsb pdb:2DK3|rcsb pdb:3DKM|reactome:R-HSA-983168|rcsb pdb:2LC3|refseq:XP_005267559.2|ensembl:ENSP00000382269|ensembl:ENSP00000450697|refseq:NP_056197.3|dip:DIP-31669N	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:/l60ZSm+P4Vlc8B79wS7+T1Zvzk9606	intact-crc:484FD6491FF008F2|rigid:MuEE9i/S5LPQpu2f1tPubY9rv98	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9UPN3	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-522925|uniprotkb:E9PJT0|uniprotkb:O75053|uniprotkb:Q5VW20|uniprotkb:Q8WXY2|uniprotkb:Q9H540|uniprotkb:Q9UKP0|uniprotkb:Q9ULG9|intact:EBI-28967632|uniprotkb:B1ALC5|uniprotkb:Q8WXY1|uniprotkb:Q96PK2	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:macf1_human(display_long)|uniprotkb:Actin cross-linking family protein 7(gene name synonym)|uniprotkb:Macrophin-1(gene name synonym)|uniprotkb:Trabeculin-alpha(gene name synonym)|uniprotkb:620 kDa actin-binding protein(gene name synonym)|uniprotkb:MACF1(gene name)|psi-mi:MACF1(display_short)|uniprotkb:ABP620(gene name synonym)|uniprotkb:ACF7(gene name synonym)|uniprotkb:KIAA0465(gene name synonym)|uniprotkb:KIAA1251(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577605|imex:IM-24624-185	author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENST00000361689|ensembl:ENSP00000354573|ensembl:ENSG00000127603|refseq:NP_036222.3|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Z6G|rcsb pdb:5VE9|rcsb pdb:5X57|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0042060"(wound healing)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|dip:DIP-50616N|mint:Q9UPN3	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:G5PesqPZZxQhwDgW0pBJSkJNcZ49606	intact-crc:91E874E5E0BC94AB|rigid:+ejD2ImerOTYUuEfDF+3mveVq5I	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P78527	uniprotkb:P49286	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577614|imex:IM-24624-186	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:DE2111CEA4CC65F1|rigid:vUNRitG1xPs25PC+SgiieBBOlZ8	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9H792	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-2609701|uniprotkb:Q6ZS78|uniprotkb:Q8TEG7|uniprotkb:Q8NCM3|uniprotkb:Q8NAZ4|ensembl:ENSP00000309230|ensembl:ENSP00000452796|ensembl:ENSP00000507603	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:peak1_human(display_long)|uniprotkb:PEAK1(gene name)|psi-mi:PEAK1(display_short)|uniprotkb:KIAA2002(gene name synonym)|uniprotkb:Sugen kinase 269(gene name synonym)|uniprotkb:Tyrosine-protein kinase SgK269(gene name synonym)|uniprotkb:Pseudopodium-enriched atypical kinase 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577641|imex:IM-24624-189	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:XP_011520335.1|refseq:XP_011520336.1|refseq:XP_011520337.1|refseq:XP_011520338.1|refseq:XP_011520339.1|refseq:XP_011520341.1|refseq:XP_011520340.1|refseq:NP_079052.2|refseq:XP_005254727.1|refseq:XP_005254728.1|refseq:XP_005254730.1|refseq:XP_005254731.1|refseq:XP_005254732.1|ensembl:ENSG00000173517(gene)|ensembl:ENST00000312493(transcript)|ensembl:ENST00000560626(transcript)|ensembl:ENST00000682557(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:6BHC|reactome:R-HSA-9013420|reactome:R-HSA-9013424|ensembl:ENSP00000309230|ensembl:ENSP00000452796|ensembl:ENSP00000507603|dip:DIP-56276N	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:z2Q9mOQSYpc1fQJHovBCFsctX749606	intact-crc:323BF356CB74E411|rigid:6Xb2MxVZ7dkbzvman7Y4+CGSh7A	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9UPN7	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-359745|uniprotkb:Q2M2H3|uniprotkb:Q504V2|uniprotkb:Q6NVJ6|uniprotkb:Q9BU97|intact:EBI-28973105|ensembl:ENSP00000414202|ensembl:ENSP00000467521	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:pp6r1_human(display_long)|uniprotkb:PPP6R1(gene name)|psi-mi:PPP6R1(display_short)|uniprotkb:KIAA1115(gene name synonym)|uniprotkb:PP6R1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym)|uniprotkb:SAPS1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577632|imex:IM-24624-188	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_055746.3|ensembl:ENSP00000414202|ensembl:ENSP00000467521|ensembl:ENSG00000105063(gene)|ensembl:ENST00000412770(transcript)|ensembl:ENST00000587283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UPN7|reactome:R-HSA-204005|dip:DIP-27589N	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:Nab2lMgz1rQizyvjdbMrJUMNB+I9606	intact-crc:38967E8137F3FDE8|rigid:cQrhKWxYs3KEAtGTP+LIYmmDOsQ	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75150	uniprotkb:P49286	intact:EBI-744408|uniprotkb:Q6AHZ6|uniprotkb:Q6N005|uniprotkb:Q7L3T6|uniprotkb:Q8N615|uniprotkb:Q96T18|uniprotkb:Q9BSV9|uniprotkb:Q9HC82|ensembl:ENSP00000325677|uniprotkb:A0A024QZG0	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:bre1b_human(display_long)|uniprotkb:95 kDa retinoblastoma-associated protein(gene name synonym)|uniprotkb:RING finger protein 40(gene name synonym)|uniprotkb:RNF40(gene name)|psi-mi:RNF40(display_short)|uniprotkb:BRE1B(gene name synonym)|uniprotkb:KIAA0661(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1B(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577623|imex:IM-24624-187	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273501.1|refseq:NP_001193962.1|refseq:NP_001193963.1|refseq:NP_055586.1|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|interpro:IPR017907|mint:O75150|reactome:R-HSA-8866654|go:"GO:0046872"(metal ion binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|ensembl:ENSG00000103549(gene)|ensembl:ENST00000324685(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2018/09/18	rogid:POkQZhEBe4cw3Y9V3YOwJDgvYJ89606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:F65B74DF8560491A|rigid:ySrHvToK/aOvHjDvMjXbDKE2D4o	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q96GM5	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-358489|intact:EBI-1760001|ensembl:ENSP00000378414|uniprotkb:Q92924|uniprotkb:Q9Y635|intact:EBI-1965109|uniprotkb:A6NN27|intact:EBI-28976725	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:smrd1_human(display_long)|uniprotkb:SMARCD1(gene name)|psi-mi:SMARCD1(display_short)|uniprotkb:BAF60A(gene name synonym)|uniprotkb:SWI/SNF complex 60 kDa subunit(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit A(gene name synonym)|uniprotkb:BRG1-associated factor 60A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577650|imex:IM-24624-190	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000066117(gene)|ensembl:ENST00000394963(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071564"(npBAF complex)|refseq:NP_003067.3|refseq:NP_620710.2|ensembl:ENST00000381513|ensembl:ENSP00000370924|ensembl:ENSP00000378414|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038041|mint:Q96GM5|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33390N	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:cwqYnl+J8glG8YjW1ps77Dd105Y9606	intact-crc:1AE0401BF2130F0B|rigid:bbRRu2ydl5k5ID+BaX4R6U47w/k	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q8WXH0	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-2372294|uniprotkb:Q540G1|uniprotkb:Q8N1S3|uniprotkb:Q8NF49|uniprotkb:Q8TER7|uniprotkb:Q8WWW3|uniprotkb:Q8WWW4|uniprotkb:Q8WWW5|uniprotkb:Q8WXH1|uniprotkb:Q9NU50|uniprotkb:Q9UFQ4|uniprotkb:Q9Y2L4|uniprotkb:Q9Y4R1|uniprotkb:Q86YP9|uniprotkb:B4DND7|uniprotkb:B4DPR6|uniprotkb:I6XXQ5|ensembl:ENSP00000341781	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:syne2_human(display_long)|uniprotkb:SYNE2(gene name)|psi-mi:SYNE2(display_short)|uniprotkb:KIAA1011(gene name synonym)|uniprotkb:NUA(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 2(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 2(gene name synonym)|uniprotkb:Nucleus and actin connecting element protein(gene name synonym)|uniprotkb:KASH domain-containing protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577659|imex:IM-24624-191	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSP00000344528|ensembl:ENSP00000341781|ensembl:ENST00000358025|ensembl:ENSP00000350719|ensembl:ENST00000458046|ensembl:ENSP00000391937|ensembl:ENST00000555002|ensembl:ENSP00000450831|ensembl:ENST00000341472|refseq:NP_055995.4|refseq:NP_878914.1|refseq:NP_878917.1|refseq:NP_878918.2|dip:DIP-53409N|ensembl:ENSG00000054654(gene)|ensembl:ENST00000344113(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005925"(focal adhesion)|go:"GO:0007097"(nuclear migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031981"(nuclear lumen)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|interpro:IPR030266|interpro:IPR036872|rcsb pdb:4DXS|rcsb pdb:4FI9|rcsb pdb:6XF1|reactome:R-HSA-1221632	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:wLHWOXR+dUHkcs93g+F2av/9wm49606	intact-crc:6ECA8ED03E5ED0EB|rigid:OLPVn+yt5/AyFn6KXFIptFlt/o4	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q96FV9	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1765605|uniprotkb:Q15219|uniprotkb:B2RBP6|uniprotkb:Q64I72|uniprotkb:Q64I73|intact:EBI-28984554|ensembl:ENSP00000261600	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:thoc1_human(display_long)|uniprotkb:hTREX84(gene name synonym)|uniprotkb:THOC1(gene name)|psi-mi:THOC1(display_short)|uniprotkb:HPR1(gene name synonym)|uniprotkb:Nuclear matrix protein p84(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577668|imex:IM-24624-192	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_005122.2|ensembl:ENSP00000261600|ensembl:ENSG00000079134(gene)|ensembl:ENST00000261600(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0048297"(negative regulation of isotype switching to IgA isotypes)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR021861|mint:Q96FV9|rcsb pdb:1WXP|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:D+lk5iFzcmd1bQRa2cx/nUyq4sI9606	intact-crc:BD49A51624F65605|rigid:EI6HxB195ezLxAJbVu83HV48tsM	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BSI4	uniprotkb:P49286	intact:EBI-717399|uniprotkb:Q9H904|uniprotkb:Q9UHC2|uniprotkb:B3W5Q7|ensembl:ENSP00000267415|ensembl:ENSP00000495019	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:tinf2_human(display_long)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577677|imex:IM-24624-193	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092744.1|refseq:NP_036593.2|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|ensembl:ENSG00000284915(gene)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:1904356"(regulation of telomere maintenance via telomere lengthening)|ensembl:ENST00000267415(transcript)|interpro:IPR029400|interpro:IPR039098|mint:Q9BSI4|rcsb pdb:3BQO|rcsb pdb:3BU8|rcsb pdb:5XYF|reactome:R-HSA-110328|reactome:R-HSA-110329|ensembl:ENST00000646576(transcript)|go:"GO:0000781"(chromosome, telomeric region)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|go:"GO:0000783"(nuclear telomere cap complex)|reactome:R-HSA-171319|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0010370"(perinucleolar chromocenter)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0016233"(telomere capping)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0032202"(telomere assembly)|ensembl:ENSG00000092330(gene)|dip:DIP-29413N	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:l/sNYfQWtGUBmGDKBRAluwdaiag9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:8B5A3B6F3BD5AABE|rigid:0b0XH7/t3pqSn4elgoVymsh9CsU	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14669	uniprotkb:P49286	intact:EBI-308443|uniprotkb:Q15644|ensembl:ENSP00000283943|uniprotkb:D4HL82|uniprotkb:Q14CA3|uniprotkb:Q14CF1|uniprotkb:Q53R87|uniprotkb:Q53TE7	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:tripc_human(display_long)|uniprotkb:TRIP12(gene name)|psi-mi:TRIP12(display_short)|uniprotkb:Thyroid receptor-interacting protein 12(gene name synonym)|uniprotkb:KIAA0045(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase for Arf(gene name synonym)|uniprotkb:ULF(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase TRIP12(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577686|imex:IM-24624-194	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004229.1|refseq:NP_001271143.1|refseq:NP_001271144.1|refseq:NP_001271145.1|ensembl:ENSG00000153827(gene)|ensembl:ENST00000283943(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016607"(nuclear speck)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|interpro:IPR037197|mint:Q14669|reactome:R-HSA-983168|refseq:NP_001335244.1|refseq:NP_001335245.1|ensembl:ENSP00000283943|ensembl:ENST00000389044|ensembl:ENST00000389045|ensembl:ENSP00000373697|ensembl:ENSP00000373696|dip:DIP-58584N	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	caution:This sequence has been withdrawn from Uniprot.|crc64:294A7C063A3332DE	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:wzXMKIUEDV4y7YE6PDU+LIPHl7U9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:BA48E34268134FF8|rigid:InJA3iWiHPzYsOVVFUN6tCvvV3w	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9BWW8	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11574440|uniprotkb:Q658J1|uniprotkb:Q5R3S1|uniprotkb:Q8IXX6|uniprotkb:Q9UGG1|ensembl:ENSP00000386280	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:apol6_human(display_long)|uniprotkb:Apolipoprotein L-VI(gene name synonym)|uniprotkb:UNQ3095/PRO21341(orf name)|uniprotkb:APOL6(gene name)|psi-mi:APOL6(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577704|imex:IM-24624-196	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_085144.1|refseq:XP_011528694.1|ensembl:ENSG00000221963(gene)|ensembl:ENST00000409652(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0042157"(lipoprotein metabolic process)|interpro:IPR008405(Apolipoprotein L)	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:UxlimE7tcUP8Im3JAvtzlaSTfeo9606	intact-crc:C2DD1E61342F8D9F|rigid:/dwUtt8gbMG1c+eJFVyOHhF6BNs	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60266	uniprotkb:P49286	intact:EBI-7958928|uniprotkb:Q53T54|intact:MINT-7290325|uniprotkb:Q9UDB1|uniprotkb:B3KT86|ensembl:ENSP00000260600|ensembl:ENSP00000505261	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:adcy3_human(display_long)|uniprotkb:ADCY3(gene name)|psi-mi:ADCY3(display_short)|uniprotkb:KIAA0511(gene name synonym)|uniprotkb:Adenylate cyclase type III(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase 3(gene name synonym)|uniprotkb:Adenylyl cyclase 3(gene name synonym)|uniprotkb:Adenylate cyclase, olfactive type(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577695|imex:IM-24624-195	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001307542.1|refseq:NP_004027.2|ensembl:ENSG00000138031(gene)|ensembl:ENST00000260600(transcript)|ensembl:ENST00000679454(transcript)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007338"(single fertilization)|go:"GO:0007340"(acrosome reaction)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008355"(olfactory learning)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0060170"(ciliary membrane)|go:"GO:1904322"(cellular response to forskolin)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR018297|interpro:IPR029787|interpro:IPR030672|interpro:IPR032628|reactome:R-HSA-163359|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-170660|reactome:R-HSA-170670|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-432040|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	comment:mint	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:q/RpqvAoauepvJ5Jci4mkJwheqE9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:CFF46B7874BF4BBA|rigid:Oi+E2WxhXUWkkQB9FLT6hSwmE0U	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9H8M9	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-715362|uniprotkb:Q9HC41|uniprotkb:D6W5J3|ensembl:ENSP00000233712|ensembl:ENSP00000377490|ensembl:ENSP00000386435|ensembl:ENSP00000386930	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:eva1a_human(display_long)|uniprotkb:EVA1A(gene name)|psi-mi:EVA1A(display_short)|uniprotkb:FAM176A(gene name synonym)|uniprotkb:Protein FAM176A(gene name synonym)|uniprotkb:TMEM166(gene name synonym)|uniprotkb:Transmembrane protein 166(gene name synonym)|uniprotkb:SP24(orf name)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577722|imex:IM-24624-198	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001128504.1|refseq:NP_115557.1|ensembl:ENSG00000115363(gene)|ensembl:ENST00000233712(transcript)|ensembl:ENST00000393913(transcript)|ensembl:ENST00000410071(transcript)|ensembl:ENST00000410113(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR039500|interpro:IPR039501|reactome:R-HSA-381426|reactome:R-HSA-8957275	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:yX9kjT0TnQ/hgcHieyzboJnywR09606	intact-crc:2A7AC668EC66FB9A|rigid:0pa71TgkOvWfZAWIc/6iXFumBFI	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P36941	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577731|imex:IM-24624-199	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:CC93B61C24478885|rigid:1v4mAC6eAckuT3Y8lLuwiqs9TX8	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HD1	uniprotkb:P49286	intact:EBI-713009|uniprotkb:Q6I9X5|uniprotkb:Q8NFT4|uniprotkb:Q9Y409|uniprotkb:A8MX90|uniprotkb:B2RAA9|ensembl:ENSP00000373322|ensembl:ENSP00000393643|ensembl:ENSP00000507127|ensembl:ENSP00000508358	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:crel1_human(display_long)|uniprotkb:CRELD1(gene name)|psi-mi:CRELD1(display_short)|uniprotkb:CIRRIN(gene name synonym)|uniprotkb:Cysteine-rich with EGF-like domain protein 1(gene name synonym)|uniprotkb:UNQ188/PRO214(orf name)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577713|imex:IM-24624-197	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026887.1|refseq:NP_001070883.1|refseq:NP_056328.2|refseq:XP_016862664.1|ensembl:ENSG00000163703(gene)|ensembl:ENST00000383811(transcript)|ensembl:ENST00000452070(transcript)|ensembl:ENST00000682783(transcript)|ensembl:ENST00000684493(transcript)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR006212(Furin-like repeat)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR021852|mint:Q96HD1	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:YCHTMCBYRLSWAJ4W+2lmt/EjUlQ9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:B0AFBFBC18C10CE5|rigid:Uuex2ZYDX+HUbbpQgAUrvdh4/Qs	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q6ZMI0	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-5235703|uniprotkb:B7ZKY5|uniprotkb:Q2TA78|uniprotkb:Q6ZMI6|uniprotkb:Q8IW83|uniprotkb:Q8J029|uniprotkb:Q96ES8|uniprotkb:B7ZKY7|uniprotkb:E1B6W7|ensembl:ENSP00000294952	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ppr21_human(display_long)|uniprotkb:PPP1R21(gene name)|psi-mi:PPP1R21(display_short)|uniprotkb:CCDC128(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 128(gene name synonym)|uniprotkb:KLRAQ motif-containing protein 1(gene name synonym)|uniprotkb:KLRAQ1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577749|imex:IM-24624-201	author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001129101.1|refseq:NP_001180404.1|refseq:NP_694539.1|ensembl:ENSG00000162869(gene)|ensembl:ENST00000294952(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0016020"(membrane)|interpro:IPR019343|interpro:IPR019348|interpro:IPR040024	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:cp4v9NF+YVUYq0eABVb/gj0TeJA9606	intact-crc:1CFF1E9408E2BB43|rigid:MbrYUGkHB6FF6EX1egR/FM++uoQ	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q5JRA6	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-2291868|uniprotkb:A8K2S0|uniprotkb:A8MT05|uniprotkb:A8MT13|uniprotkb:B7Z430|uniprotkb:Q3S4X3|uniprotkb:Q5JRB0|uniprotkb:Q14083|uniprotkb:Q5JRA5|uniprotkb:Q5JRB1|uniprotkb:Q5JRB2|uniprotkb:Q6UVY8|uniprotkb:Q86Y60|uniprotkb:Q8N8M5|uniprotkb:Q92580|intact:EBI-2803073|ensembl:ENSP00000340900	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:tgo1_human(display_long)|uniprotkb:TANGO(gene name synonym)|uniprotkb:MIA3(gene name)|psi-mi:MIA3(display_short)|uniprotkb:KIAA0268(gene name synonym)|uniprotkb:C219-reactive peptide(gene name synonym)|uniprotkb:D320(gene name synonym)|uniprotkb:UNQ6077/PRO20088(orf name)|uniprotkb:Melanoma inhibitory activity protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577740|imex:IM-24624-200	author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_940953.2|refseq:NP_001287796.1|ensembl:ENSG00000154305(gene)|ensembl:ENST00000344922(transcript)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0009306"(protein secretion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|refseq:NP_001310992.1|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:2000402"(negative regulation of lymphocyte migration)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|rcsb pdb:5KYN|rcsb pdb:5KYU|rcsb pdb:5KYW|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-8957275	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:DGy7mQTlQIbcaklbpG7jmdj9G/I9606	intact-crc:FC950CE7BE3AF21D|rigid:bQAkolZiUYvWF9zHmmymcbP0Yio	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q96GF1	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-2340249|uniprotkb:A8K5C1|uniprotkb:A9X3T8|uniprotkb:Q8N900|ensembl:ENSP00000320508|ensembl:ENSP00000427755	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:rn185_human(display_long)|uniprotkb:RNF185(gene name)|psi-mi:RNF185(display_short)|uniprotkb:RING finger protein 185(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF185(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577758|imex:IM-24624-202	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001129297.1|refseq:NP_689480.2|ensembl:ENSG00000138942(gene)|ensembl:ENST00000326132(transcript)|ensembl:ENST00000518626(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:ivzbt31KPTKL/Rc1Wzs3h80XJac9606	intact-crc:F7C92A6847AC8CF4|rigid:NO6g/DJWAQvHheuIs4fkqgGOAkg	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UP95	uniprotkb:P49286	intact:EBI-7244836|intact:EBI-11577771|uniprotkb:Q13953|uniprotkb:B7ZAV0|uniprotkb:O75893|uniprotkb:O60632|intact:MINT-1191426|uniprotkb:F5H0S9|uniprotkb:B4DZ82|uniprotkb:B4DF69|uniprotkb:Q96LD5|uniprotkb:F5H3C0|uniprotkb:F5H066|uniprotkb:B4DR04|ensembl:ENSP00000318557	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:s12a4_human(display_long)|uniprotkb:SLC12A4(gene name)|psi-mi:SLC12A4(display_short)|uniprotkb:KCC1(gene name synonym)|uniprotkb:Electroneutral potassium-chloride cotransporter 1(gene name synonym)|uniprotkb:Erythroid K-Cl cotransporter 1(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577767|imex:IM-24624-203	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139436.1|refseq:NP_001139433.1|refseq:NP_001139434.1|refseq:NP_005063.1|refseq:NP_001139435.1|interpro:IPR000622(K-Cl Co-transporter, type 1)|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR004842(Na-K-Cl cotransporter superfamily)|interpro:IPR018491|rcsb pdb:6KKR|rcsb pdb:6KKT|rcsb pdb:6KKU|rcsb pdb:7AIP|rcsb pdb:7AIQ|rcsb pdb:7AIR|reactome:R-HSA-426117|interpro:IPR000076(K-Cl co-transporter)|ensembl:ENSG00000124067(gene)|ensembl:ENST00000316341(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045202"(synapse)|go:"GO:0055064"(chloride ion homeostasis)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0140157"(ammonium import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	comment:mint|comment:homomint|function:"Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity"	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/17	rogid:wyweg+klinikkDDzNhNdIwomyDQ9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:5242B0CC62A0C9C7|rigid:HVLYOXY1Yf+prGTfZmll9VZ3g4o	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9Y6M5	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-10982148|ensembl:ENSP00000355968|uniprotkb:Q0VAK9|uniprotkb:Q9BZF6	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:znt1_human(display_long)|uniprotkb:SLC30A1(gene name)|psi-mi:SLC30A1(display_short)|uniprotkb:Solute carrier family 30 member 1(gene name synonym)|uniprotkb:ZNT1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577792|imex:IM-24624-204	author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_067017.2|ensembl:ENSG00000170385(gene)|ensembl:ENST00000367001(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0010312"(detoxification of zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030315"(T-tubule)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046929"(negative regulation of neurotransmitter secretion)|go:"GO:0070509"(calcium ion import)|go:"GO:0070574"(cadmium ion transmembrane transport)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0071584"(negative regulation of zinc ion transmembrane import)|go:"GO:0071585"(detoxification of cadmium ion)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|mint:Q9Y6M5|reactome:R-HSA-435368	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:XL8LmzhYwIWnN1yPFHnDkoJg2TE9606	intact-crc:E25361891D9F5840|rigid:vxrGanzsqXxbgdVmXQuV1tScVZ0	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q13433	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11343415|uniprotkb:B4DR49|uniprotkb:Q96HP5|uniprotkb:Q8IXR3|uniprotkb:B4E224|ensembl:ENSP00000269187|ensembl:ENSP00000465915	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:s39a6_human(display_long)|uniprotkb:SLC39A6(gene name)|psi-mi:SLC39A6(display_short)|uniprotkb:Estrogen-regulated protein LIV-1(gene name synonym)|uniprotkb:LIV1(gene name synonym)|uniprotkb:Solute carrier family 39 member 6(gene name synonym)|uniprotkb:ZIP6(gene name synonym)|uniprotkb:Zrt- and Irt-like protein 6(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577801|imex:IM-24624-205	author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_036451.3|refseq:NP_001092876.1|refseq:XP_011524202.1|refseq:XP_011524203.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0009986"(cell surface)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0071578"(zinc ion import across plasma membrane)|interpro:IPR003689(Zinc/iron permease)|reactome:R-HSA-442380|go:"GO:0005385"(zinc ion transmembrane transporter activity)|ensembl:ENSG00000141424(gene)|ensembl:ENST00000269187(transcript)|ensembl:ENST00000590986(transcript)	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:Ab1Ra9K7xoOlr7A7j9hd5gjAw9w9606	intact-crc:1C9FF7FA76631143|rigid:XmTHeks7fFo2jGVtIgpLf4DuKtM	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60337	uniprotkb:P49286	intact:EBI-2684600|uniprotkb:A5PKZ4|uniprotkb:O14670|uniprotkb:Q86X77|uniprotkb:D3DTC8|intact:EBI-28971061|ensembl:ENSP00000274140|uniprotkb:B4DKJ2|uniprotkb:B4DT33	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:marh6_human(display_long)|uniprotkb:MARCHF6(gene name)|psi-mi:MARCHF6(display_short)|uniprotkb:Doa10 homolog(gene name synonym)|uniprotkb:KIAA0597(gene name synonym)|uniprotkb:MARCH6(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 6(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein VI(gene name synonym)|uniprotkb:Protein TEB-4(gene name synonym)|uniprotkb:RING finger protein 176(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF6(gene name synonym)|uniprotkb:RNF176(gene name synonym)|uniprotkb:TEB4(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577810|imex:IM-24624-206	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000274140|ensembl:ENST00000449913|ensembl:ENSP00000414643|ensembl:ENST00000503788|ensembl:ENSP00000425930|refseq:NP_005876.2|ensembl:ENSG00000145495(gene)|ensembl:ENST00000274140(transcript)|go:"GO:0000835"(ER ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|refseq:NP_001257589.1|refseq:NP_001257590.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O60337|reactome:R-HSA-901032|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|dip:DIP-56134N	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:ow2W2xIcL82tgIHRS0SxlY4Ffjs9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:694CE5F08360364D|rigid:gSR3GUys1+VN0tRbmbf9chxGlQ8	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9Y6M7	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1044546|uniprotkb:O60350|uniprotkb:Q6AHZ9|uniprotkb:Q9HC88|uniprotkb:Q9UIB9|ensembl:ENSP00000295736|uniprotkb:A6NIA8|intact:EBI-11577841|uniprotkb:B2CI53|uniprotkb:B5M451|uniprotkb:B5M452|uniprotkb:B5M453|uniprotkb:B6DY52|uniprotkb:B6DY53|uniprotkb:C9JST9|uniprotkb:B5M449|uniprotkb:D3K174|uniprotkb:D3K175|intact:EBI-10982200	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:s4a7_human(display_long)|uniprotkb:Sodium bicarbonate cotransporter 2(gene name synonym)|uniprotkb:Sodium bicarbonate cotransporter 2b(gene name synonym)|uniprotkb:Solute carrier family 4 member 7(gene name synonym)|uniprotkb:SLC4A7(gene name)|psi-mi:SLC4A7(display_short)|uniprotkb:BT(gene name synonym)|uniprotkb:NBC2(gene name synonym)|uniprotkb:NBC2B(gene name synonym)|uniprotkb:NBC3(gene name synonym)|uniprotkb:SBC2(gene name synonym)|uniprotkb:SLC4A6(gene name synonym)|uniprotkb:NBCn1(gene name synonym)|uniprotkb:"Electroneutral Na/HCO(3) cotransporter"(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577837|imex:IM-24624-209	author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_003606.3|ensembl:ENSG00000033867(gene)|ensembl:ENST00000295736(transcript)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008510"("sodium:bicarbonate symporter activity")|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0032420"(stereocilium)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060117"(auditory receptor cell development)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|reactome:R-HSA-425381|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9035034|reactome:R-HSA-9013406|refseq:NP_001245308.1|refseq:NP_001245309.1|refseq:NP_001308032.1|refseq:NP_001308033.1|refseq:NP_001308034.1|refseq:NP_001308035.1|refseq:NP_001308036.1|refseq:NP_001308037.1|refseq:XP_016863017.1|refseq:XP_016863018.1	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/16	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:vsq90qG3qxPyZgkoyvS0MPamvOg9606	intact-crc:55FD18F1197A6393|rigid:wNm12k8l65g+U2OJn+6tKAXeD0A	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17861	uniprotkb:P49286	intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577819|imex:IM-24624-207	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:2125A901180F02AD|rigid:zsBooVFop8xMsPf89hcnm6t6o/4	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12772	uniprotkb:P49286	intact:EBI-465059|uniprotkb:Q86V36|uniprotkb:Q6GTH7|uniprotkb:Q9UH04|ensembl:ENSP00000354476|uniprotkb:Q05BD5	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:srbp2_human(display_long)|uniprotkb:SREBF2(gene name)|psi-mi:SREBF2(display_short)|uniprotkb:SREBP2(gene name synonym)|uniprotkb:Sterol regulatory element-binding transcription factor 2(gene name synonym)|uniprotkb:BHLHD2(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 2(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577828|imex:IM-24624-208	author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198911(gene)|ensembl:ENST00000361204(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032937"(SREBP-SCAP-Insig complex)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005829"(cytosol)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090370"(negative regulation of cholesterol efflux)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1UKL|reactome:R-HSA-1655829|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-9619665|refseq:NP_004590.2|dip:DIP-263N	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:OkTB/ZjBgPVLKu333KVw2AKrE5M9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:137055659A92433B|rigid:OsCJ3ycBnKd7aWeFfX7MuSrYPqc	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P21333	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577875|imex:IM-24624-211	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	intact-crc:DE1FAD8467AD097D|rigid:UgFYuRzZFrLVXDQOJn7+w8PuSbA	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P12081	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1057566|uniprotkb:B4DY73|uniprotkb:B4DHQ1|uniprotkb:D6REN6|uniprotkb:J3KNE5|ensembl:ENSP00000425634	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:hars1_human(display_long)|uniprotkb:HARS1(gene name)|psi-mi:HARS1(display_short)|uniprotkb:HARS(gene name synonym)|uniprotkb:HRS(gene name synonym)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577866|imex:IM-24624-210	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001244969.1|refseq:NP_002100.2|refseq:NP_001244970.1|refseq:NP_001244971.1|ensembl:ENSG00000170445(gene)|ensembl:ENST00000504156(transcript)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000738(WHEP-TRS)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR033656|interpro:IPR036621|interpro:IPR041715|mint:P12081|rcsb pdb:1X59|rcsb pdb:2LW7|rcsb pdb:4G84|rcsb pdb:4G85|rcsb pdb:4PHC|rcsb pdb:4X5O|rcsb pdb:5W6M|rcsb pdb:6O76|reactome:R-HSA-379716|dip:DIP-37596N	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:7o34bzWC+/C+mlCDTcvUOHbaCxE9606	intact-crc:B80364253AFF3DAE|rigid:uEKMKvCWPhcO/2YHHm6VZrxdXh4	false	sufficient binding region:226-254	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12841	uniprotkb:P49286	intact:EBI-2349801|uniprotkb:Q549Z0|uniprotkb:A8K523|uniprotkb:B4DTT5|uniprotkb:D3DN90|ensembl:ENSP00000295633	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:fstl1_human(display_long)|uniprotkb:FSTL1(gene name)|psi-mi:FSTL1(display_short)|uniprotkb:FRP(gene name synonym)|uniprotkb:Follistatin-like protein 1(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577884|imex:IM-24624-212	author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009016.1|ensembl:ENSG00000163430(gene)|ensembl:ENST00000295633(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0008201"(heparin binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR011992(EF-Hand type)|interpro:IPR015369(Follistatin)|interpro:IPR036058|reactome:R-HSA-201451|reactome:R-HSA-381426|reactome:R-HSA-8957275	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:2Y10WyTpml76Ksjw+X7dXUozFg09606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:31691D4402BE7E01|rigid:O5QNsOdEUc4JoVxVtCwnfnTyLhI	false	-	sufficient binding region:226-254	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z460	uniprotkb:P48039	intact:EBI-913476|uniprotkb:B7ZLX3|uniprotkb:O75118|uniprotkb:Q2KHQ9|uniprotkb:Q5H9P0|uniprotkb:Q8N5B8|uniprotkb:Q9BQT5|ensembl:ENSP00000263710|intact:EBI-2562829|uniprotkb:A2RU21|uniprotkb:F5GWS0|intact:EBI-10967465	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:clap1_human(display_long)|uniprotkb:CLASP1(gene name)|psi-mi:CLASP1(display_short)|uniprotkb:KIAA0622(gene name synonym)|uniprotkb:MAST1(gene name synonym)|uniprotkb:Cytoplasmic linker-associated protein 1(gene name synonym)|uniprotkb:Multiple asters homolog 1(gene name synonym)|uniprotkb:Protein Orbit homolog 1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577899|imex:IM-24624-213	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001135745.1|refseq:NP_001135746.1|refseq:NP_001193980.1|refseq:NP_056097.1|ensembl:ENSG00000074054(gene)|ensembl:ENST00000263710(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008017"(microtubule binding)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0016020"(membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031111"(negative regulation of microtubule polymerization or depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031592"(centrosomal corona)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045180"(basal cortex)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|refseq:XP_011509150.1|ensembl:ENSP00000263710|ensembl:ENST00000397587|ensembl:ENSP00000380717|ensembl:ENST00000409078|ensembl:ENSP00000386442|ensembl:ENST00000541377|ensembl:ENSP00000441625|interpro:IPR024395|interpro:IPR028399|interpro:IPR034085|rcsb pdb:4K92|rcsb pdb:6MQ5|rcsb pdb:6MQ7|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-428890|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:ZhVWdhW2ylZHeewHZ63lg5FQT1c9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:D9799994EC38099F|rigid:f+U23jnvgc6VG+pLrdZgfOMKp+E	false	-	sufficient binding region:120-147,213-241,295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26022	uniprotkb:P48039	intact:EBI-11574553|uniprotkb:B2R6T6|uniprotkb:Q38M82|ensembl:ENSP00000295927	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:ptx3_human(display_long)|uniprotkb:Pentaxin-related protein PTX3(gene name synonym)|uniprotkb:TNFAIP5(gene name synonym)|uniprotkb:TSG14(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 5(gene name synonym)|uniprotkb:Tumor necrosis factor-inducible gene 14 protein(gene name synonym)|uniprotkb:PTX3(gene name)|psi-mi:PTX3(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577917|imex:IM-24624-215	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002843.2|ensembl:ENSG00000163661(gene)|ensembl:ENST00000295927(transcript)|go:"GO:0001550"(ovarian cumulus expansion)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0001872"("(1->3)-beta-D-glucan binding")|go:"GO:0001878"(response to yeast)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0008228"(opsonization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0044869"(negative regulation by host of viral exo-alpha-sialidase activity)|go:"GO:0044871"(negative regulation by host of viral glycoprotein metabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:1903016"(negative regulation of exo-alpha-sialidase activity)|go:"GO:1903019"(negative regulation of glycoprotein metabolic process)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001759(Pentaxin)|interpro:IPR006558(LamG-like jellyroll fold)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|interpro:IPR042837|reactome:R-HSA-6798695	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:E2p0QaxS5/8mpgyOghoPCB+WHx09606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:061E41705B5A20C5|rigid:DYZgF0A5dRrFZAjEHnH7vfW0nko	false	-	sufficient binding region:120-147,213-241,295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q14157	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577926|imex:IM-24624-216	author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606	intact-crc:2C5DB88388FE81B0|rigid:7+BZre0mxmx7cLO0kU83mNa27O4	false	sufficient binding region:120-147,213-241,295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14573	uniprotkb:P48039	intact:EBI-351055|uniprotkb:Q14649|uniprotkb:Q5TAQ2|intact:EBI-28978202|ensembl:ENSP00000363435|ensembl:ENSP00000475177	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:itpr3_human(display_long)|uniprotkb:ITPR3(gene name)|psi-mi:ITPR3(display_short)|uniprotkb:Type 3 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 3(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577908|imex:IM-24624-214	author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002215.2|ensembl:ENSP00000363435|ensembl:ENSP00000475177|ensembl:ENSG00000096433(gene)|ensembl:ENST00000374316(transcript)|ensembl:ENST00000605930(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043235"(receptor complex)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:Q14573|rcsb pdb:6DQJ|rcsb pdb:6DQN|rcsb pdb:6DQS|rcsb pdb:6DQV|rcsb pdb:6DQZ|rcsb pdb:6DR0|rcsb pdb:6DR2|rcsb pdb:6DRA|rcsb pdb:6DRC|rcsb pdb:6UQK|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|go:"GO:0007613"(memory)|reactome:R-HSA-983695	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:O+1OC4E0IrAOt+D672eXnhWHy3I9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:3F3FA71D49827C12|rigid:2e7rfpdduEzQaGogdvfhmsAEjfk	false	-	sufficient binding region:120-147,213-241,295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q70CQ2	uniprotkb:P48039	intact:EBI-6256020|uniprotkb:A8MWD0|uniprotkb:B3KWU9|uniprotkb:O60316|uniprotkb:O94834|uniprotkb:Q3B777|uniprotkb:Q6P6C9|uniprotkb:Q7L8P6|uniprotkb:Q8N3T9|uniprotkb:Q8TBW2|uniprotkb:Q9UGA1|ensembl:ENSP00000381577	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:ubp34_human(display_long)|uniprotkb:USP34(gene name)|psi-mi:USP34(display_short)|uniprotkb:KIAA0570(gene name synonym)|uniprotkb:KIAA0729(gene name synonym)|uniprotkb:Deubiquitinating enzyme 34(gene name synonym)|uniprotkb:Ubiquitin thioesterase 34(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 34(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577935|imex:IM-24624-217	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055524.3|ensembl:ENSG00000115464(gene)|ensembl:ENST00000398571(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR038765|mint:Q70CQ2|reactome:R-HSA-201681|reactome:R-HSA-5689880	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:ouPBRH6ndkATju67iwZYOl1wYWM9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:3A48E855804D5D12|rigid:ChIOT0V84bX6rY5R0ZwnAfsy3I4	false	-	sufficient binding region:120-147,213-241,295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q96IU4	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-11574698|uniprotkb:Q8N8W5|uniprotkb:Q86VK8|ensembl:ENSP00000354841|ensembl:ENSP00000378455|ensembl:ENSP00000420065|ensembl:ENSP00000433388	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:abheb_human(display_long)|uniprotkb:CCG1-interacting factor B(gene name synonym)|uniprotkb:CIB(gene name synonym)|uniprotkb:ABHD14B(gene name)|psi-mi:ABHD14B(display_short)|uniprotkb:Alpha/beta hydrolase domain-containing protein 14B(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577944|imex:IM-24624-218	author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001139786.1|refseq:NP_001241682.1|refseq:NP_116139.1|ensembl:ENSG00000114779(gene)|ensembl:ENST00000361143(transcript)|ensembl:ENST00000395008(transcript)|ensembl:ENST00000483233(transcript)|ensembl:ENST00000525795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050427"(3'-phosphoadenosine 5'-phosphosulfate metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|rcsb pdb:1IMJ|reactome:R-HSA-156584	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:GYG2FqQ44o7VWBw/b4DG5mIAkSQ9606	intact-crc:3B831C30A64D1834|rigid:yjnDJBv13vpntLOsJnK1eSa/Dc0	false	sufficient binding region:120-147,213-241,295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9Y2J4	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577962|imex:IM-24624-220	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	intact-crc:A2F86C6BC5E21C08|rigid:hZpRQFf8o9/9xAfzA+arORpvZKE	false	sufficient binding region:120-147,213-241,295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q8TDY4	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2609717|uniprotkb:Q86UY1|uniprotkb:Q9NXK2|uniprotkb:B3KRW0|uniprotkb:Q6P9F4|uniprotkb:B4DHH4|ensembl:ENSP00000338769|ensembl:ENSP00000488946	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:asap3_human(display_long)|uniprotkb:ASAP3(gene name)|psi-mi:ASAP3(display_short)|uniprotkb:DDEFL1(gene name synonym)|uniprotkb:UPLC1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor-like 1(gene name synonym)|uniprotkb:Protein up-regulated in liver cancer 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577971|imex:IM-24624-221	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSP00000338769|ensembl:ENST00000437606|ensembl:ENSP00000408826|ensembl:ENST00000495646|ensembl:ENSP00000436150|ensembl:ENST00000634513|ensembl:ENSP00000488934|ensembl:ENSP00000488946|ensembl:ENST00000635198|ensembl:ENSP00000488953|refseq:NP_001137250.1|refseq:NP_060177.2|interpro:IPR028775|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR038508|interpro:IPR043593|rcsb pdb:2B0O|rcsb pdb:3LVQ|rcsb pdb:3LVR|ensembl:ENSG00000088280(gene)|ensembl:ENSG00000282854(gene)|ensembl:ENST00000336689(transcript)|ensembl:ENST00000634561(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0016477"(cell migration)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051492"(regulation of stress fiber assembly)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:Q9AlcelYGI/3GuYuFrW/05agPXY9606	intact-crc:F4F84EF848DB6FD5|rigid:qILAz0gC6K0g3iId1/OHsm3CoUs	false	sufficient binding region:120-147,213-241,295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P12814	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577953|imex:IM-24624-219	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001093.1|refseq:NP_001123477.1|refseq:NP_001123476.1|dip:DIP-33184N|ensembl:ENSG00000072110(gene)|ensembl:ENST00000193403(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:guTURyt26f1ort4NAlYyabNc+WE9606	intact-crc:6892E2E291BED0E6|rigid:B37uElhECAV+eINF5a1TdFeSK58	false	sufficient binding region:120-147,213-241,295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q53G59	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577989|imex:IM-24624-223	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	intact-crc:28F4534E59D3A449|rigid:PD7rMGPzUX+r5niYVcMXzW6M/4s	false	sufficient binding region:120-147,213-241,295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P46379	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577980|imex:IM-24624-222	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	intact-crc:9E6F8E54588F8749|rigid:2p/g/yoMIAIqYxPHiChAT4WZKjI	false	sufficient binding region:120-147,213-241,295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q9Y2R4	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-395458|uniprotkb:Q86YG1|uniprotkb:Q8N213|uniprotkb:Q9NVE0|uniprotkb:Q9Y482|ensembl:ENSP00000479504|ensembl:ENSP00000480030	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:ddx52_human(display_long)|uniprotkb:DDX52(gene name)|psi-mi:DDX52(display_short)|uniprotkb:ROK1(gene name synonym)|uniprotkb:DEAD box protein 52(gene name synonym)|uniprotkb:ATP-dependent RNA helicase ROK1-like(gene name synonym)|uniprotkb:HUSSY-19(orf name)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578007|imex:IM-24624-225	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_008941.3|ensembl:ENSG00000277594(gene)|ensembl:ENSG00000278053(gene)|ensembl:ENST00000615769(transcript)|ensembl:ENST00000617633(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044764|mint:Q9Y2R4|rcsb pdb:3DKP|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_001278405.1	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:M3yY9StxHlLGPK0WOqPHwgnmwLU9606	intact-crc:FE710811DA10F081|rigid:U++XZUoGqAbX8gQ9+KqbgzeCirM	false	sufficient binding region:120-147,213-241,295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P34059	uniprotkb:P48039	intact:EBI-11574573|uniprotkb:Q86VK3|ensembl:ENSP00000268695	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:galns_human(display_long)|uniprotkb:Chondroitinsulfatase(gene name synonym)|uniprotkb:Galactose-6-sulfate sulfatase(gene name synonym)|uniprotkb:N-acetylgalactosamine-6-sulfate sulfatase(gene name synonym)|uniprotkb:GALNS(gene name)|psi-mi:GALNS(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578016|imex:IM-24624-226	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000503.1|ensembl:ENSG00000141012(gene)|ensembl:ENST00000268695(transcript)|go:"GO:0003943"(N-acetylgalactosamine-4-sulfatase activity)|go:"GO:0004065"(arylsulfatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0008484"(sulfuric ester hydrolase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043890"(N-acetylgalactosamine-6-sulfatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000917(Sulphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR024607|interpro:IPR035626|rcsb pdb:4FDI|rcsb pdb:4FDJ|reactome:R-HSA-2022857|reactome:R-HSA-2206290|reactome:R-HSA-6798695	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:2FZxcLUYorRN69wKbb5KO+oMkU89606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:9C747E0358369C02|rigid:f/unG4pelNEWdJP3F+CxBzMLEdU	false	-	sufficient binding region:120-147,213-241,295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13618	uniprotkb:P48039	intact:EBI-456129|uniprotkb:O75415|uniprotkb:Q569L3|uniprotkb:Q9UBI8|uniprotkb:B8ZZC3|uniprotkb:Q9UET7|uniprotkb:A8K536|ensembl:ENSP00000264414	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:cul3_human(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:KIAA0617(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11577998|imex:IM-24624-224	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003581.1|refseq:NP_001244126.1|refseq:NP_001244127.1|dip:DIP-31611N|ensembl:ENSG00000036257(gene)|ensembl:ENST00000264414(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000922"(spindle pole)|go:"GO:0001831"(trophectodermal cellular morphogenesis)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017145"(stem cell division)|go:"GO:0030030"(cell projection organization)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072576"(liver morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13618|rcsb pdb:2MYL|rcsb pdb:2MYM|rcsb pdb:4AP2|rcsb pdb:4APF|rcsb pdb:4EOZ|rcsb pdb:4HXI|rcsb pdb:5NLB|rcsb pdb:6I2M|reactome:R-HSA-4641258|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9706019|reactome:R-HSA-983168	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:xI/8pHB9nckOW629STOqKba4KzQ9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:BE104634AC5F69CB|rigid:6o0zqVp698fbpnZK5gGiyyUO5bI	false	-	sufficient binding region:120-147,213-241,295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q8WXI9	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644|ensembl:ENSP00000458280|ensembl:ENSP00000489184	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578025|imex:IM-24624-227	author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_065750.1|refseq:XP_005245421.1|dip:DIP-36054N|ensembl:ENSG00000143614(gene)|ensembl:ENSG00000261992(gene)|ensembl:ENST00000368655(transcript)|ensembl:ENST00000576342(transcript)|ensembl:ENST00000634544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606	intact-crc:78E86601B350F54D|rigid:Jsw8WkREBR0O/i7rZIs+/sA5qFA	false	sufficient binding region:120-147,213-241,295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P31943	uniprotkb:P48039	intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578034|imex:IM-24624-228	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:2825CB01066DE030|rigid:C1+sL3AnpVCi/p6pqrq88LTwRZQ	false	-	sufficient binding region:120-147,213-241,295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75970	uniprotkb:P48039	intact:EBI-821405|intact:EBI-2684724|uniprotkb:Q4LE30|uniprotkb:B7ZMI4|uniprotkb:A6NLC2|uniprotkb:O43798|uniprotkb:Q5CZ80|uniprotkb:Q5JTX3|uniprotkb:Q5JTX6|uniprotkb:Q5JTX7|uniprotkb:Q5JUC3|uniprotkb:Q5JUC4|uniprotkb:Q5VZ62|uniprotkb:Q8N790|intact:EBI-10961605|uniprotkb:B2RTS3|ensembl:ENSP00000320006	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:mpdz_human(display_long)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym)|uniprotkb:MPDZ(gene name)|psi-mi:MPDZ(display_short)|uniprotkb:MUPP1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578052|imex:IM-24624-230	author score:A	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006716948.1|refseq:XP_006716949.1|refseq:XP_006716950.1|refseq:XP_006716951.1|refseq:XP_006716952.1|refseq:XP_006716954.1|refseq:NP_003820.2|refseq:NP_001248335.1|refseq:NP_001248336.1|refseq:NP_001317566.1|refseq:XP_016870742.1|ensembl:ENSG00000107186(gene)|ensembl:ENST00000319217(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O75970|rcsb pdb:2FCF|rcsb pdb:2FNE|rcsb pdb:2IWN|rcsb pdb:2IWO|rcsb pdb:2IWP|rcsb pdb:2IWQ|rcsb pdb:2O2T|rcsb pdb:2OPG|rcsb pdb:2QG1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:Q5QzIDHLoL/sWqQI7r/Kb4VLSdY9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:3E49B3EB2C896B59|rigid:qKqbVIloFHECWpGKvImjMTbc1SM	false	-	sufficient binding region:120-147,213-241,295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z442	uniprotkb:P48039	intact:EBI-11574650|uniprotkb:Q96Q08|uniprotkb:Q6ZSP2|uniprotkb:Q96CL2|uniprotkb:Q6UEE1|uniprotkb:Q8N1H9|uniprotkb:Q6ZN46	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:pk1l2_human(display_long)|uniprotkb:KIAA1879(gene name synonym)|uniprotkb:PC1-like 2 protein(gene name synonym)|uniprotkb:PC1L2(gene name synonym)|uniprotkb:Polycystin-1L2(gene name synonym)|uniprotkb:PKD1L2(gene name)|psi-mi:PKD1L2(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578043|imex:IM-24624-229	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000203(GPS)|interpro:IPR000922(D-galactoside/L-rhamnose binding SUEL lectin)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001304(C-type lectin)|interpro:IPR002859(PKD/REJ-like protein)|interpro:IPR003915(Polycystic kidney disease type 2 protein)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR014010(Egg jelly receptor, REJ-like)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|refseq:NP_001070248.1|refseq:NP_001265352.1|refseq:NP_001265354.1|refseq:NP_443124.3|interpro:IPR042060|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0050982"(detection of mechanical stimulus)|interpro:IPR036392|interpro:IPR043159	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2018/04/06	rogid:ldpUEwFn+ADTvXtqLQU9HUpS1849606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:B807E8306357C20B|rigid:5jNh0OaxEZstlXhuovQDLwXkq/E	false	-	sufficient binding region:120-147,213-241,295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y6M5	uniprotkb:P48039	intact:EBI-10982148|ensembl:ENSP00000355968|uniprotkb:Q0VAK9|uniprotkb:Q9BZF6	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:znt1_human(display_long)|uniprotkb:SLC30A1(gene name)|psi-mi:SLC30A1(display_short)|uniprotkb:Solute carrier family 30 member 1(gene name synonym)|uniprotkb:ZNT1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578070|imex:IM-24624-232	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067017.2|ensembl:ENSG00000170385(gene)|ensembl:ENST00000367001(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0010312"(detoxification of zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030315"(T-tubule)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046929"(negative regulation of neurotransmitter secretion)|go:"GO:0070509"(calcium ion import)|go:"GO:0070574"(cadmium ion transmembrane transport)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0071584"(negative regulation of zinc ion transmembrane import)|go:"GO:0071585"(detoxification of cadmium ion)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|mint:Q9Y6M5|reactome:R-HSA-435368	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:XL8LmzhYwIWnN1yPFHnDkoJg2TE9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:345C97A0C27AB46C|rigid:5meQ/sIIQK8AKlWr1Qm5IzyvKe4	false	-	sufficient binding region:120-147,213-241,295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9EPI6	uniprotkb:P48039	intact:EBI-6899705|uniprotkb:Q5PPF6|uniprotkb:Q7TSC6|uniprotkb:Q7TSC8|uniprotkb:Q9EPI4|uniprotkb:Q9EPI5	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:nsmf_rat(display_long)|uniprotkb:Nsmf(gene name)|psi-mi:Nsmf(display_short)|uniprotkb:Jac(gene name synonym)|uniprotkb:Nelf(gene name synonym)|uniprotkb:Juxtasynaptic attractor of caldendrin on dendritic boutons protein(gene name synonym)|uniprotkb:Nasal embryonic luteinizing hormone-releasing hormone factor(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578061|imex:IM-24624-231	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0005886"(plasma membrane)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:0097440"(apical dendrite)|mint:Q9EPI6|interpro:IPR033374|rgd:619819|refseq:NP_001257555.1|refseq:NP_001257556.1|refseq:NP_001257557.1|refseq:NP_476538.2	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 6)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:7roymdKtL+QSCC6O/qfhzsLvSaA10116	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:16A6ECFA9DCC63BE|rigid:C475S5SRpTQwEvFEHjrAfvDQln4	false	-	sufficient binding region:120-147,213-241,295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60709	uniprotkb:P48039	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578085|imex:IM-24624-233	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:138726C6D3386D4B|rigid:xotCTpzxEhjH/oBsNPx+mSksLZM	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P31939	uniprotkb:P48039	intact:EBI-1048599|uniprotkb:Q13856|uniprotkb:Q53S28|uniprotkb:A8K202|uniprotkb:E9PBU3|ensembl:ENSP00000236959	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:pur9_human(display_long)|uniprotkb:ATIC(gene name)|psi-mi:ATIC(display_short)|uniprotkb:PURH(gene name synonym)|uniprotkb:OK/SW-cl.86(orf name)|uniprotkb:AICAR transformylase/inosine monophosphate cyclohydrolase(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578103|imex:IM-24624-235	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004035.2|ensembl:ENSG00000138363(gene)|ensembl:ENST00000236959(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046452"(dihydrofolate metabolic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|rcsb pdb:1P4R|rcsb pdb:1PKX|rcsb pdb:1PL0|rcsb pdb:5UY8|rcsb pdb:5UZ0|reactome:R-HSA-73817	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:Xe3388w/LOBYgag9P8Gp3IGo9wU9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:CC4C34EECB7DBB96|rigid:fUPUywAE7WMgH1q2pxDpNoWioDE	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P50553	uniprotkb:P48039	intact:EBI-957042|uniprotkb:Q9BQ30|ensembl:ENSP00000266744|uniprotkb:A8K3C4	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:ascl1_human(display_long)|uniprotkb:ASCL1(gene name)|psi-mi:ASCL1(display_short)|uniprotkb:ASH1(gene name synonym)|uniprotkb:BHLHA46(gene name synonym)|uniprotkb:HASH1(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 46(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578094|imex:IM-24624-234	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0060487"(lung epithelial cell differentiation)|ensembl:ENSG00000139352(gene)|ensembl:ENST00000266744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003358"(noradrenergic neuron development)|go:"GO:0003359"(noradrenergic neuron fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007423"(sensory organ development)|go:"GO:0007507"(heart development)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021530"(spinal cord oligodendrocyte cell fate specification)|go:"GO:0021750"(vestibular nucleus development)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030856"(regulation of epithelial cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048469"(cell maturation)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0050883"(musculoskeletal movement, spinal reflex action)|go:"GO:0051593"(response to folic acid)|go:"GO:0060163"(subpallium neuron fate commitment)|go:"GO:0060165"(regulation of timing of subpallium neuron differentiation)|go:"GO:0060166"(olfactory pit development)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048666"(neuron development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061100"(lung neuroendocrine cell differentiation)|go:"GO:0061102"(stomach neuroendocrine cell differentiation)|go:"GO:0060579"(ventral spinal cord interneuron fate commitment)|go:"GO:0061103"(carotid body glomus cell differentiation)|go:"GO:0061104"(adrenal chromaffin cell differentiation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0070888"(E-box binding)|go:"GO:0071259"(cellular response to magnetism)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|reactome:R-HSA-9031628|refseq:NP_004307.2	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:RFGT3dxB08IBopnYytmfJL1YRmQ9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:870FD1BADE5E5002|rigid:gZm7nv7vfVtWNPNtx8MyOy3S2W4	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WTW3	uniprotkb:P48039	intact:EBI-368371|uniprotkb:Q9P2G6|uniprotkb:Q9NPV9|ensembl:ENSP00000299886	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:cog1_human(display_long)|uniprotkb:COG1(gene name)|psi-mi:COG1(display_short)|uniprotkb:KIAA1381(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 1(gene name synonym)|uniprotkb:LDLB(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578121|imex:IM-24624-237	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061184.1|ensembl:ENSG00000166685(gene)|ensembl:ENST00000299886(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|interpro:IPR033370|mint:Q8WTW3|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|go:"GO:0015031"(protein transport)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:zUXskbnET4Wp0wRsjxwtE33ccCA9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:E0940EFA3182E2A0|rigid:R/RGVqk+WJhp3qZ4s36yv/+/fe4	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94830	uniprotkb:P48039	intact:EBI-8444979|uniprotkb:B3KXB5|intact:MINT-4649256|intact:MINT-4940977|uniprotkb:B3KWV2|uniprotkb:Q9H8X7|ensembl:ENSP00000380352|ensembl:ENSP00000429932	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:ddhd2_human(display_long)|uniprotkb:DDHD2(gene name)|psi-mi:DDHD2(display_short)|uniprotkb:KIAA0725(gene name synonym)|uniprotkb:KIAA0725p(gene name synonym)|uniprotkb:SAMWD1(gene name synonym)|uniprotkb:DDHD domain-containing protein 2(gene name synonym)|uniprotkb:SAM, WWE and DDHD domain-containing protein 1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578130|imex:IM-24624-238	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011542758.1|refseq:NP_001157704.1|refseq:NP_056029.2|refseq:XP_005273511.1|refseq:XP_005273512.1|refseq:XP_016868741.1|refseq:XP_016868742.1|refseq:XP_016868743.1|refseq:XP_016868744.1|refseq:XP_016868745.1|ensembl:ENSG00000085788(gene)|ensembl:ENST00000397166(transcript)|ensembl:ENST00000520272(transcript)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0016020"(membrane)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0046872"(metal ion binding)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004170(WWE)|interpro:IPR004177(DDHD)|interpro:IPR013761(Sterile alpha motif-type)|reactome:R-HSA-1483166	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	comment:mint|function:Phospholipase that hydrolyzes preferentially phosphatidic acid and phosphatidylethanolamine. May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:3Tw/oOkOaBJqJ0jyUBrsYy1ASyM9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:751CB1DE70FB502F|rigid:erLaO9Y26Ux6QUEB/a89dLBMAEk	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q549M8	uniprotkb:P48039	intact:EBI-8456490|intact:MINT-5002977	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:q549m8_human(display_long)|uniprotkb:C14orf166(gene name)|psi-mi:C14orf166(display_short)|uniprotkb:hCG_22667(orf name)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578112|imex:IM-24624-236	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057123.1|interpro:IPR019265|go:"GO:0005654"(nucleoplasm)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:39AFFD1F0B1B5161|rigid:5MJcbsy0KN2/kz45UcSxNnbwAS4	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P23610	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-5663973|uniprotkb:Q8IXP3|uniprotkb:Q5HY66|intact:EBI-28971382|ensembl:ENSP00000358518|ensembl:ENSP00000477530|ensembl:ENSP00000479624	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:hap40_human(display_long)|uniprotkb:CpG island protein(gene name synonym)|uniprotkb:F8A1(gene name)|psi-mi:F8A1(display_short)|uniprotkb:F8A2(gene name)|psi-mi:F8A2(display_short)|uniprotkb:F8A3(gene name)|psi-mi:F8A3(display_short)|uniprotkb:Factor VIII intron 22 protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578148|imex:IM-24624-240	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSP00000358518|ensembl:ENSP00000479624|ensembl:ENSP00000477530|refseq:NP_001007524.1|refseq:NP_001007525.1|refseq:NP_036283.2|ensembl:ENSG00000277150(gene)|ensembl:ENSG00000288709(gene)|ensembl:ENSG00000288722(gene)|ensembl:ENST00000369505(transcript)|ensembl:ENST00000610495(transcript)|ensembl:ENST00000622749(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0016604"(nuclear body)|go:"GO:0099518"(vesicle cytoskeletal trafficking)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR039494|rcsb pdb:6EZ8|rcsb pdb:6X9O|rcsb pdb:7DXJ|rcsb pdb:7DXK	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:btVfuF/KKUSWmbRdXS4b4Vdi3wE9606	intact-crc:99556338596E1819|rigid:EcWbfHbD1fGAd+2/BPr7WPbv0wY	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:O60344	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-3906484|uniprotkb:A5PLK8|uniprotkb:Q6UW36|uniprotkb:Q96NX4|uniprotkb:Q6NTG7|uniprotkb:Q8NFD7|uniprotkb:Q96NX3|uniprotkb:Q9BRZ8	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:ece2_human(display_long)|uniprotkb:ECE2(gene name)|psi-mi:ECE2(display_short)|uniprotkb:KIAA0604(gene name synonym)|uniprotkb:UNQ403/PRO740(orf name)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578139|imex:IM-24624-239	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	go:"GO:0030658"(transport vesicle membrane)|reactome:R-HSA-375276|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0007420"(brain development)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0016486"(peptide hormone processing)|refseq:NP_001032401.1|refseq:NP_001093590.1|refseq:NP_001093591.1|refseq:NP_055508.3|refseq:NP_115707.2|ensembl:ENSG00000145194|interpro:IPR024079|interpro:IPR000718(Peptidase M13, neprilysin)|interpro:IPR018497|interpro:IPR008753(Peptidase M13)|rcsb pdb:2PXX|go:"GO:0000139"(Golgi membrane)|ensembl:ENSP00000314295|ensembl:ENSP00000350066|ensembl:ENSP00000352052|ensembl:ENSP00000384223|ensembl:ENSP00000385846|go:"GO:0007507"(heart development)|interpro:IPR029063|ensembl:ENST00000324557|ensembl:ENST00000357474|ensembl:ENST00000359140|ensembl:ENST00000402825|ensembl:ENST00000404464|interpro:IPR029733|mint:MINT-8417701	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:B9eJri6iiOLo8LWayOP1mMB7gKw9606	intact-crc:EDF2E7A97095FB97|rigid:pniDj8RVjB8g8O8t/IhXFuURqtI	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P31629	uniprotkb:P48039	intact:EBI-2514157|ensembl:ENSP00000012134|ensembl:ENSP00000356575|ensembl:ENSP00000356576|uniprotkb:Q02646|uniprotkb:Q9NS05|uniprotkb:Q5THT5	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:zep2_human(display_long)|uniprotkb:HIVEP2(gene name)|psi-mi:HIVEP2(display_short)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 2(gene name synonym)|uniprotkb:MHC-binding protein 2(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578166|imex:IM-24624-242	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000010818(gene)|ensembl:ENST00000012134(transcript)|ensembl:ENST00000367603(transcript)|ensembl:ENST00000367604(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:XP_016866294.1|refseq:NP_006725.3	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:/QXXmthWJq/FkgWwIqkVb1z16EU9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:1DFD4E85B7493851|rigid:oQJgHzRMXBRmCw8RUQ42C1J/8Gw	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:O94808	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-6916534|ensembl:ENSP00000253778|uniprotkb:Q53XM2|uniprotkb:Q9BWS4	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:gfpt2_human(display_long)|uniprotkb:GFPT2(gene name)|psi-mi:GFPT2(display_short)|uniprotkb:D-fructose-6-phosphate amidotransferase 2(gene name synonym)|uniprotkb:"Glutamine:fructose-6-phosphate amidotransferase 2"(gene name synonym)|uniprotkb:Hexosephosphate aminotransferase 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578157|imex:IM-24624-241	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000131459(gene)|ensembl:ENST00000253778(transcript)|go:"GO:0004360"("glutamine-fructose-6-phosphate transaminase (isomerizing) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR005855(Glucosamine-fructose-6-phosphate aminotransferase, isomerising)|interpro:IPR017932|interpro:IPR029055|interpro:IPR035466|interpro:IPR035490|reactome:R-HSA-446210|refseq:NP_005101.1	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:e0qXUjWfS1KMkEBSEES+IgoPnLI9606	intact-crc:DBB28FC887C4A836|rigid:7TOFsJA/yy6YHhWu6vWrIT1gG/g	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q05469	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-721601|uniprotkb:Q3LRT2|uniprotkb:Q6NSL7|ensembl:ENSP00000244289	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:lips_human(display_long)|uniprotkb:LIPE(gene name)|psi-mi:LIPE(display_short)|uniprotkb:Monoacylglycerol lipase LIPE(gene name synonym)|uniprotkb:Retinyl ester hydrolase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578175|imex:IM-24624-243	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_005348.2|go:"GO:0046485"(ether lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0047376"(all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity)|go:"GO:0050253"(retinyl-palmitate esterase activity)|go:"GO:0102258"(1,3-diacylglycerol acylhydrolase activity)|go:"GO:0102259"(1,2-diacylglycerol acylhydrolase activity)|interpro:IPR002168(Lipase, GDXG, active site)|interpro:IPR010468(Hormone-sensitive lipase, N-terminal)|interpro:IPR013094(Alpha/beta hydrolase fold-3)|interpro:IPR029058|interpro:IPR033140|reactome:R-HSA-163560|ensembl:ENSG00000079435(gene)|ensembl:ENST00000244289(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0033878"(hormone-sensitive lipase activity)|go:"GO:0046340"(diacylglycerol catabolic process)|refseq:XP_005258997.1|refseq:XP_006723281.1|refseq:XP_016882299.1	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:pfJlMy3xEXQDx6URLLc+TBOURNs9606	intact-crc:B0F8C87AD492C43A|rigid:M3PqF4r0kRp0Gkr9VFU1uJExB0E	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:P08253	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-1033518|uniprotkb:B2R6U1|uniprotkb:Q9UCJ8|ensembl:ENSP00000219070|uniprotkb:E9PE45|uniprotkb:B4DWH3	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:mmp2_human(display_long)|uniprotkb:MMP2(gene name)|psi-mi:MMP2(display_short)|uniprotkb:CLG4A(gene name synonym)|uniprotkb:72 kDa gelatinase(gene name synonym)|uniprotkb:Matrix metalloproteinase-2(gene name synonym)|uniprotkb:Gelatinase A(gene name synonym)|uniprotkb:TBE-1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578184|imex:IM-24624-244	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001289437.1|refseq:NP_001289438.1|refseq:NP_001289439.1|ensembl:ENSG00000087245(gene)|ensembl:ENST00000219070(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001955"(blood vessel maturation)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007566"(embryo implantation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030017"(sarcomere)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048771"(tissue remodeling)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071492"(cellular response to UV-A)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000585(Hemopexin)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR002477(Peptidoglycan binding-like)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR024079|interpro:IPR028708|interpro:IPR033739|interpro:IPR036365|interpro:IPR036375|interpro:IPR036943|rcsb pdb:1CK7|rcsb pdb:1CXW|rcsb pdb:1EAK|rcsb pdb:1GEN|rcsb pdb:1GXD|rcsb pdb:1HOV|rcsb pdb:1J7M|rcsb pdb:1KS0|rcsb pdb:1QIB|rcsb pdb:1RTG|rcsb pdb:3AYU|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-381426|reactome:R-HSA-3928665|reactome:R-HSA-6785807|reactome:R-HSA-9009391|refseq:NP_001121363.1|refseq:NP_004521.1	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:s0IHoSkzT9GNfkkLZsVsV7cIf1g9606	intact-crc:EC8A5EB0CADDB9F2|rigid:d2aumzaYvA2OPrlJdBVCmROAjuI	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q6ZW49	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-743225|ensembl:ENSP00000380376|ensembl:ENSP00000384048|uniprotkb:O15404|uniprotkb:Q6N099|uniprotkb:Q6ZWH9|uniprotkb:Q7Z315|uniprotkb:Q86UN0|uniprotkb:Q8N4P9|uniprotkb:Q96HP2	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:paxi1_human(display_long)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym)|uniprotkb:PAXIP1(gene name)|psi-mi:PAXIP1(display_short)|uniprotkb:PAXIP1L(gene name synonym)|uniprotkb:PTIP(gene name synonym)|uniprotkb:CAGF28(orf name)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578193|imex:IM-24624-245	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	go:"GO:0006310"(DNA recombination)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060717"(chorion development)|go:"GO:1902749"(regulation of cell cycle G2/M phase transition)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR037886|mint:Q6ZW49|rcsb pdb:3SQD|reactome:R-HSA-5617472|reactome:R-HSA-5693571|refseq:NP_031375.3|ensembl:ENSG00000157212(gene)|ensembl:ENST00000397192(transcript)|ensembl:ENST00000404141(transcript)|go:"GO:0000416"(positive regulation of histone H3-K36 methylation)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|refseq:XP_005249596.1|refseq:XP_016867370.1|dip:DIP-41786N	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:djzoPtMxXMP9LBvpzVNBcq04QEY9606	intact-crc:5143784AD35167B7|rigid:Wnd10U/JNkRNzxYrDf1y4yqAehY	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q969Q6	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2561661|uniprotkb:B4DEN7|uniprotkb:Q6P4G2|uniprotkb:Q9NWR9|uniprotkb:Q86TZ3|uniprotkb:Q5GJ56|uniprotkb:Q5GJ55|uniprotkb:D3DS97|uniprotkb:D3DS98|ensembl:ENSP00000261475	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:p2r3c_human(display_long)|uniprotkb:C14orf10(gene name synonym)|uniprotkb:G5PR(gene name synonym)|uniprotkb:Protein phosphatase subunit G5PR(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.6A/6C(gene name synonym)|uniprotkb:PPP2R3C(gene name)|psi-mi:PPP2R3C(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578202|imex:IM-24624-246	author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001292085.1|refseq:NP_001292084.1|refseq:NP_060387.2|ensembl:ENSG00000092020(gene)|ensembl:ENST00000261475(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002759"(regulation of antimicrobial humoral response)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048536"(spleen development)|go:"GO:0051900"(regulation of mitochondrial depolarization)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR039865|interpro:IPR041534|mint:Q969Q6|refseq:XP_005267839.1	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:kuXZ55Pqx8CoMysWfAjipVXHh9U9606	intact-crc:E7B48B28F3AE8E8C|rigid:H3rC3hRZ1vAoLX4EAxFOq7fhgUs	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14498	uniprotkb:P48039	intact:EBI-395290|uniprotkb:A5D8W2|uniprotkb:B0BLV3|uniprotkb:Q14499|uniprotkb:A2RRD3|uniprotkb:E1P5S0|uniprotkb:E1P5S1|ensembl:ENSP00000253363	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:rbm39_human(display_long)|uniprotkb:HCC1(gene name synonym)|uniprotkb:RBM39(gene name)|psi-mi:RBM39(display_short)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma protein 1(gene name synonym)|uniprotkb:Splicing factor HCC1(gene name synonym)|uniprotkb:RNPC2(gene name synonym)|uniprotkb:CAPER alpha(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578211|imex:IM-24624-247	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229528.1|refseq:NP_001229529.1|refseq:NP_004893.1|refseq:NP_909122.1|ensembl:ENSG00000131051(gene)|ensembl:ENST00000253363(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q14498|rcsb pdb:2JRS|rcsb pdb:2MHN|rcsb pdb:4OO6|rcsb pdb:4OZ0|rcsb pdb:4OZ1|rcsb pdb:4YUD|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6SJ7|rcsb pdb:6UD7|rcsb pdb:6UE5|dip:DIP-32928N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:/e7HNZt0CtcDKTwF8BqSwNpyufc9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:5796A72E27E7F80C|rigid:HjC+/a3u8qfUEmaiKBWFGKMVvQY	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14924	uniprotkb:P48039	intact:EBI-7358493|intact:MINT-154790|uniprotkb:B1AQ31|uniprotkb:O14923|uniprotkb:B1AQ32|uniprotkb:O14922|uniprotkb:O75338|uniprotkb:O43510|uniprotkb:B1AQ30|uniprotkb:E7EMN9|uniprotkb:Q147X0|uniprotkb:Q8WX95|ensembl:ENSP00000338509|ensembl:ENSP00000339381|uniprotkb:B7Z764	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:rgs12_human(display_long)|uniprotkb:RGS12(gene name)|psi-mi:RGS12(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578220|imex:IM-24624-248	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511845.1|refseq:NP_002917.1|refseq:NP_937872.1|refseq:NP_937870.1|refseq:XP_016864018.1|refseq:XP_016864020.1|refseq:XP_016864021.1|refseq:XP_016864022.1|ensembl:ENSG00000159788(gene)|ensembl:ENST00000336727(transcript)|ensembl:ENST00000344733(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003109(GoLoco)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036034|interpro:IPR036305|interpro:IPR037880|rcsb pdb:2EBZ|rcsb pdb:2KV8|reactome:R-HSA-418594|refseq:XP_006713968.1|refseq:XP_006713969.1|refseq:XP_006713970.1	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form|comment:mint	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:86ann2gpd8ZhURj5bP5EhPwz9Fo9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:5C53F6698BD705B2|rigid:6O/YB0lwooPWLjzNUA2gSeUdHsY	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q99496	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578229|imex:IM-24624-249	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	intact-crc:603773285FC6C736|rigid:PeYC45nX0vRE7Hi/m/dsVKKBImU	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14893	uniprotkb:P48039	intact:EBI-443648|ensembl:ENSP00000250379|ensembl:ENSP00000308533|ensembl:ENSP00000379548|ensembl:ENSP00000416827|uniprotkb:Q2M3B3|uniprotkb:Q9H4F5|uniprotkb:Q9NS77|uniprotkb:Q9NS78|uniprotkb:Q9NS79|uniprotkb:B2R9W8	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:gemi2_human(display_long)|uniprotkb:GEMIN2(gene name)|psi-mi:GEMIN2(display_short)|uniprotkb:SIP1(gene name synonym)|uniprotkb:Component of gems 2(gene name synonym)|uniprotkb:Survival of motor neuron protein-interacting protein 1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578247|imex:IM-24624-251	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092208(gene)|ensembl:ENST00000250379(transcript)|ensembl:ENST00000308317(transcript)|ensembl:ENST00000396249(transcript)|ensembl:ENST00000412033(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR017364(Survival of motor neuron protein interacting, gemin2)|interpro:IPR035426|mint:O14893|rcsb pdb:2LEH|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|refseq:NP_001009182.1|refseq:NP_001009183.1|refseq:NP_003607.1|dip:DIP-32605N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:cCbpiHhHdfq+SNoIud5xipHgYVA9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:A86F0A269F1198D1|rigid:KV6P1K8g8fkxjTndi57pljkvriY	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NV70	uniprotkb:P48039	intact:EBI-1045313|uniprotkb:Q504V4|uniprotkb:Q8WUE7|uniprotkb:Q96T15|uniprotkb:Q9NZE4|ensembl:ENSP00000326514|ensembl:ENSP00000370695	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:exoc1_human(display_long)|uniprotkb:Exocyst complex component Sec3(gene name synonym)|uniprotkb:EXOC1(gene name)|psi-mi:EXOC1(display_short)|uniprotkb:SEC3(gene name synonym)|uniprotkb:SEC3L1(gene name synonym)|uniprotkb:BM-012(orf name)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578238|imex:IM-24624-250	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020095.1|refseq:NP_060731.2|refseq:NP_839955.1|ensembl:ENSG00000090989(gene)|ensembl:ENST00000346134(transcript)|ensembl:ENST00000381295(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051607"(defense response to virus)|go:"GO:0090543"(Flemming body)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|interpro:IPR019160|interpro:IPR028258|mint:Q9NV70|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:XP_016863898.1|dip:DIP-37579N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:DKEfnn4CJkBSIdGRfVy+znSPOrc9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:D7C88AB7FE2C2BA2|rigid:xvUS8ThQ549QG5VwDAl/iUAXvJk	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75093	uniprotkb:P48039	intact:EBI-947791|uniprotkb:Q8WWZ2|uniprotkb:Q9UIL7|uniprotkb:Q5T0V1|ensembl:ENSP00000266058	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:slit1_human(display_long)|uniprotkb:Multiple epidermal growth factor-like domains protein 4(gene name synonym)|uniprotkb:SLIT1(gene name)|psi-mi:SLIT1(display_short)|uniprotkb:KIAA0813(gene name synonym)|uniprotkb:MEGF4(gene name synonym)|uniprotkb:SLIL1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578256|imex:IM-24624-252	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003052.2|ensembl:ENSG00000187122(gene)|ensembl:ENST00000266058(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007097"(nuclear migration)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051964"(negative regulation of synapse assembly)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR032675|mint:O75093|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428542|reactome:R-HSA-8985801|reactome:R-HSA-9010553	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:CLzbkIsFRc56n2LK/zvue0dA+4Q9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:E9337987C04003EB|rigid:JSq38Lki/b2MvoBOLcxx8CXuSfY	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:O95295	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578265|imex:IM-24624-253	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606	intact-crc:166486012EA176C5|rigid:BIvKgzxtEHCd0aYA1EeMnFv4TuY	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61764	uniprotkb:P48039	intact:EBI-960169|uniprotkb:Q28208|uniprotkb:Q62759|uniprotkb:Q64320|uniprotkb:Q96TG8|uniprotkb:B1AM97|uniprotkb:Q68CM6|ensembl:ENSP00000362396	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:stxb1_human(display_long)|uniprotkb:STXBP1(gene name)|psi-mi:STXBP1(display_short)|uniprotkb:UNC18A(gene name synonym)|uniprotkb:Protein unc-18 homolog 1(gene name synonym)|uniprotkb:Protein unc-18 homolog A(gene name synonym)|uniprotkb:N-Sec1(gene name synonym)|uniprotkb:p67(gene name synonym)|uniprotkb:MUNC18-1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578283|imex:IM-24624-255	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027392.1|refseq:NP_003156.1|ensembl:ENSG00000136854(gene)|ensembl:ENST00000373299(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0002576"(platelet degranulation)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0005739"(mitochondrion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007412"(axon target recognition)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031630"(regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032229"(negative regulation of synaptic transmission, GABAergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:0106022"(positive regulation of vesicle docking)|go:"GO:1903296"(positive regulation of glutamate secretion, neurotransmission)|go:"GO:2000367"(regulation of acrosomal vesicle exocytosis)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|mint:P61764|rcsb pdb:6L03|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-422356|reactome:R-HSA-6794361|reactome:R-HSA-888590	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:yUYi89hDkfMdQ1BdH52swZQFCLk9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:7EE54DDA827710DB|rigid:E+PP2IuscVbxoFhllRQQyHr6dCk	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P30626	uniprotkb:P48039	intact:EBI-750459|uniprotkb:D6W5Q0|intact:EBI-2623494|uniprotkb:A8MTH6|uniprotkb:B4DKK2|ensembl:ENSP00000265729	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:sorcn_human(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578274|imex:IM-24624-254	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_944490.1|refseq:NP_003121.1|refseq:NP_001243820.1|refseq:NP_001243821.1|dip:DIP-40970N|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)|go:"GO:0001508"(action potential)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0030315"(T-tubule)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901077"(regulation of relaxation of muscle)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|rcsb pdb:2JC2|rcsb pdb:4U8D|rcsb pdb:4UPG|rcsb pdb:4USL|rcsb pdb:5MRA|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P30626|rcsb pdb:1JUO	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	crc64:A4829C7650A5E3FA	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:upE31IMimaotkgnYa7HYr7EYAxc9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:F9430D740F5FF8F7|rigid:WGmh1rCx2ztpOLnFcfs0sN025qY	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:P48039	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578301|imex:IM-24624-257	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:91516FC62795EDEF|rigid:/t60qJEFuZf9CtlBnKle/25+5ig	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22314	uniprotkb:P48039	intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578292|imex:IM-24624-256	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:367FFDB65DBE2DB8|rigid:xdAP5dDj/4pDeZDoXKXU5AeeTmU	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48039	uniprotkb:Q96RU2	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	intact:EBI-2512342|ensembl:ENSP00000003302|uniprotkb:B0YJC0|uniprotkb:B0YJC1|uniprotkb:Q9P213|intact:EBI-2796288|uniprotkb:Q6NZX9	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:ubp28_human(display_long)|uniprotkb:USP28(gene name)|psi-mi:USP28(display_short)|uniprotkb:KIAA1515(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 28(gene name synonym)|uniprotkb:Deubiquitinating enzyme 28(gene name synonym)|uniprotkb:Ubiquitin thioesterase 28(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578310|imex:IM-24624-258	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000048028(gene)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR009060(UBA-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:Q96RU2|rcsb pdb:2LVA|rcsb pdb:2MUU|rcsb pdb:6H4H|rcsb pdb:6H4I|rcsb pdb:6HEH|rcsb pdb:6HEI|rcsb pdb:6HEJ|rcsb pdb:6HEK|reactome:R-HSA-5689880|ensembl:ENST00000003302(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_065937.1|refseq:NP_001333187.1|refseq:NP_001333202.1	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	rogid:axlPKHiS0KlPbl2dNx2h12/LtY09606	intact-crc:A3C9FC8B68D48BD7|rigid:LlpJ7YkBi6qGbfcf1bPJ2Hw1hBo	false	sufficient binding region:295-350	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9GZX5	uniprotkb:P48039	intact:EBI-396421|uniprotkb:Q9HAQ4|uniprotkb:Q96G73|ensembl:ENSP00000243644	intact:EBI-1188238|uniprotkb:B0M0L2|uniprotkb:A0AVC5|ensembl:ENSP00000302811	psi-mi:zn350_human(display_long)|uniprotkb:Zinc finger protein ZBRK1(gene name synonym)|uniprotkb:Zinc finger and BRCA1-interacting protein with a KRAB domain 1(gene name synonym)|uniprotkb:KRAB zinc finger protein ZFQR(gene name synonym)|uniprotkb:ZNF350(gene name)|psi-mi:ZNF350(display_short)|uniprotkb:ZBRK1(gene name synonym)	psi-mi:mtr1a_human(display_long)|uniprotkb:MTNR1A(gene name)|psi-mi:MTNR1A(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578319|imex:IM-24624-259	author score:E	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067645.3|ensembl:ENSG00000256683(gene)|refseq:XP_016882587.1|refseq:XP_016882588.1|refseq:XP_016882589.1|ensembl:ENST00000243644(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q9GZX5|reactome:R-HSA-212436|reactome:R-HSA-3899300	refseq:NP_005949.1|ensembl:ENSG00000168412(gene)|ensembl:ENST00000307161(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0097159"(organic cyclic compound binding)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME2|rcsb pdb:6ME3|rcsb pdb:6ME4|rcsb pdb:6ME5|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 5)"|author-confidence:E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:n3L44uqErawnnBhZCDI2B7hnZxQ9606	rogid:67bek8BOFfpTfkNE+mnxgJ4ZrYg9606	intact-crc:98A818F8D5384C6E|rigid:hEc4oaVcty+ooXp6VZyT6cEga9I	false	-	sufficient binding region:295-350	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9H0C5	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-935503|uniprotkb:A6NMI8|uniprotkb:Q9BX71|uniprotkb:Q9NWN4|ensembl:ENSP00000261721	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:btbd1_human(display_long)|uniprotkb:BTBD1(gene name)|psi-mi:BTBD1(display_short)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 8(gene name synonym)|uniprotkb:NS5ATP8(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578328|imex:IM-24624-260	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001011885.1|refseq:NP_079514.1|ensembl:ENSG00000064726(gene)|ensembl:ENST00000261721(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR012983(PHR)|interpro:IPR038648|reactome:R-HSA-8951664|reactome:R-HSA-983168	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:fRSh7JVRI2O2o8m7WCEjydcX1QM9606	intact-crc:12E61910EFEAC273|rigid:39Uzfd1NVd8BazS3mD+rMQtZPnY	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y4F9	uniprotkb:P49286	intact:EBI-2798942|uniprotkb:A6NHP2|uniprotkb:Q5VV38|uniprotkb:Q5VV37|uniprotkb:Q9BQ28|uniprotkb:Q13529|intact:EBI-12131068|ensembl:ENSP00000259698|ensembl:ENSP00000482957|intact:EBI-13096912	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:ripr2_human(display_long)|uniprotkb:RIPOR2(gene name)|psi-mi:RIPOR2(display_short)|uniprotkb:C6orf32(gene name synonym)|uniprotkb:DIFF48(gene name synonym)|uniprotkb:FAM65B(gene name synonym)|uniprotkb:KIAA0386(gene name synonym)|uniprotkb:PL48(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578346|imex:IM-24624-262	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273376.1|refseq:NP_001273375.1|refseq:NP_055537.2|refseq:NP_056948.2|refseq:XP_016867015.1|refseq:XP_016867016.1|ensembl:ENSG00000111913(gene)|ensembl:ENST00000259698(transcript)|ensembl:ENST00000613507(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006935"(chemotaxis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030175"(filopodium)|go:"GO:0032420"(stereocilium)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1903904"(negative regulation of establishment of T cell polarity)|go:"GO:1905872"(negative regulation of protein localization to cell leading edge)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000391"(positive regulation of neutrophil extravasation)|go:"GO:2000405"(negative regulation of T cell migration)|go:"GO:2001107"(negative regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026136|interpro:IPR031780|interpro:IPR033035|reactome:R-HSA-9662360|reactome:R-HSA-9662361	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:c96hMI1PasEb6udn1jNd5ze3fT89606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:22E731DF59FBBE2E|rigid:yiXsR//VT77a7hL7vJ16I2iTHwg	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q63HM2	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1104540|uniprotkb:Q9BQG8|uniprotkb:Q9H9F2|uniprotkb:A8MXM2|ensembl:ENSP00000384801	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:pcx4_human(display_long)|uniprotkb:PCNX4(gene name)|psi-mi:PCNX4(display_short)|uniprotkb:C14orf135(gene name synonym)|uniprotkb:FBP2(gene name synonym)|uniprotkb:Hepatitis C virus F protein-binding protein 2(gene name synonym)|uniprotkb:PCNXL4(gene name synonym)|uniprotkb:Pecanex homolog protein 4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578337|imex:IM-24624-261	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000126773(gene)|ensembl:ENST00000406854(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007735(Pecanex)|interpro:IPR039797|refseq:NP_071940.4|refseq:NP_001317106.1	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:rf5CFSLdXxG+w6Uyr6+pbvD090E9606	intact-crc:917BAF007A3AD95E|rigid:+Lu99QKjVwUa5AGO5n1f9MtjEvQ	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96MW5	uniprotkb:P49286	intact:EBI-720875|ensembl:ENSP00000305459|uniprotkb:Q8WVV6|uniprotkb:Q9H6F8|uniprotkb:Q0VAK2	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:cog8_human(display_long)|uniprotkb:Component of oligomeric Golgi complex 8(gene name synonym)|uniprotkb:COG8(gene name)|psi-mi:COG8(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578364|imex:IM-24624-264	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000213380(gene)|ensembl:ENST00000306875(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|interpro:IPR007255(Dor1-like protein)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR016632(Conserved oligomeric Golgi complex, COG8)|mint:Q96MW5|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_115758.3	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:X9AZmEQ+B2Jc9kwFXAgxZp6S0sI9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:C9B277D0CE2BC5C4|rigid:ETcR/q5yMcLLTsdi1Es8Nztt3IQ	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9UQE7	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578373|imex:IM-24624-265	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606	intact-crc:6933FBFD8C1D32E7|rigid:u7J7uBn8qOh4cmfiRvgOBgkwA+Q	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9H9E3	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-368382|uniprotkb:Q96D40|uniprotkb:Q9BRF0|uniprotkb:Q9BVZ2|uniprotkb:Q9H5Y4|uniprotkb:Q9Y3W3|uniprotkb:B4DMN8|uniprotkb:C9JS23	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:cog4_human(display_long)|uniprotkb:COG4(gene name)|psi-mi:COG4(display_short)|uniprotkb:Component of oligomeric Golgi complex 4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578355|imex:IM-24624-263	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	mint:Q9H9E3|refseq:NP_001182068.1|refseq:NP_056201.2|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048213"(Golgi vesicle prefusion complex stabilization)|interpro:IPR013167(COG4 transport)|rcsb pdb:3HR0|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|dip:DIP-32635N	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:Zphojrpw0bzNCK/pnMNps+K1y7U9606	intact-crc:6AC47B43465D9354|rigid:V1g4R5+ef8tp2AatIex/5VcYyII	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q14204	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-356015|intact:EBI-4399546|uniprotkb:Q6DKQ7|uniprotkb:Q8WU28|uniprotkb:Q92814|uniprotkb:Q9Y4G5|uniprotkb:B0I1R0|intact:EBI-28969816|ensembl:ENSP00000348965	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:dyhc1_human(display_long)|uniprotkb:DYNC1H1(gene name)|psi-mi:DYNC1H1(display_short)|uniprotkb:DNECL(gene name synonym)|uniprotkb:KIAA0325(gene name synonym)|uniprotkb:DNCH1(gene name synonym)|uniprotkb:DNCL(gene name synonym)|uniprotkb:DHC1(gene name synonym)|uniprotkb:DYHC(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578391|imex:IM-24624-267	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001367.2|ensembl:ENSP00000348965|ensembl:ENSG00000197102(gene)|ensembl:ENST00000360184(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|mint:Q14204|rcsb pdb:2BOR|rcsb pdb:2BOT|rcsb pdb:5NUG|rcsb pdb:5OWO|rcsb pdb:6F1T|rcsb pdb:6F1U|rcsb pdb:6F1V|rcsb pdb:6F1Y|rcsb pdb:6F38|rcsb pdb:6F3A|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|dip:DIP-37544N	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:nI5RCxHByU3dxtLnPMPEjJlx1Fc9606	intact-crc:A1FB0348E62973F7|rigid:ejqO2Q/KQUVyX0uWyWvzUvAbfWA	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q8TDJ6	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-5653014|uniprotkb:O94938|uniprotkb:B2RTR3|uniprotkb:B7ZMH3|uniprotkb:F5GWF1|ensembl:ENSP00000251076	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:dmxl2_human(display_long)|uniprotkb:KIAA0856(gene name synonym)|uniprotkb:Rabconnectin-3(gene name synonym)|uniprotkb:DMXL2(gene name)|psi-mi:DMXL2(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578382|imex:IM-24624-266	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001167587.1|refseq:NP_056078.2|refseq:NP_001167588.1|ensembl:ENSG00000104093(gene)|ensembl:ENST00000251076(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043291"(RAVE complex)|go:"GO:0098992"(neuronal dense core vesicle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022033|interpro:IPR036322	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:RytycxvrFz8wabGFVQf7f2WJMr09606	intact-crc:8A0DDEF98949F7A0|rigid:13S34dTo90r52YvazE5wGxdDSJw	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q8N201	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-724549|uniprotkb:A6NJ44|uniprotkb:Q6NT70|uniprotkb:Q6UX74|uniprotkb:Q8WV40|uniprotkb:Q96D36|uniprotkb:Q9NTD1|uniprotkb:Q9P2A8|uniprotkb:Q9Y3W8|ensembl:ENSP00000385722	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:int1_human(display_long)|uniprotkb:INTS1(gene name)|psi-mi:INTS1(display_short)|uniprotkb:KIAA1440(gene name synonym)|uniprotkb:UNQ1821/PRO3434(orf name)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578409|imex:IM-24624-269	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001073922.2|ensembl:ENSG00000164880(gene)|ensembl:ENST00000404767(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016180"(snRNA processing)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032039"(integrator complex)|go:"GO:0034474"(U2 snRNA 3'-end processing)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022145|interpro:IPR038902|mint:Q8N201|rcsb pdb:7CUN|reactome:R-HSA-6807505|dip:DIP-48476N	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:kjJ0Sb3GOWfMXGcrxanGTX+f0VU9606	intact-crc:713203B13C0FEB52|rigid:3X9o0b8/YVODKIX3NnKguT4hJ0k	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NCM8	uniprotkb:P49286	intact:EBI-2512957|ensembl:ENSP00000364887|uniprotkb:Q7Z363|uniprotkb:O00432|uniprotkb:Q9HAE4|uniprotkb:Q8N977|uniprotkb:Q3C1U8|uniprotkb:Q6ZMX7|uniprotkb:Q16693|uniprotkb:Q6ZUM6|uniprotkb:Q4AC93|uniprotkb:Q92815|intact:EBI-2860086	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:dyhc2_human(display_long)|uniprotkb:DYNC2H1(gene name)|psi-mi:DYNC2H1(display_short)|uniprotkb:DYH1B(gene name synonym)|uniprotkb:KIAA1997(gene name synonym)|uniprotkb:Cytoplasmic dynein 2 heavy chain(gene name synonym)|uniprotkb:Dynein cytoplasmic heavy chain 2(gene name synonym)|uniprotkb:Dynein heavy chain isotype 1B(gene name synonym)|uniprotkb:Dynein heavy chain 11(gene name synonym)|uniprotkb:DHC1B(gene name synonym)|uniprotkb:DHC2(gene name synonym)|uniprotkb:DNCH2(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578400|imex:IM-24624-268	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041658|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|rcsb pdb:4RH7|reactome:R-HSA-5610787|reactome:R-HSA-5620924|ensembl:ENSG00000187240(gene)|ensembl:ENST00000375735(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007030"(Golgi organization)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0030286"(dynein complex)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030900"(forebrain development)|go:"GO:0031514"(motile cilium)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0045177"(apical part of cell)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097542"(ciliary tip)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR026815|interpro:IPR026983|refseq:NP_001073932.1|refseq:NP_001368.2	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:c6bU2mT13JkjPNR9maL9+/R3IIg9606	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:6254C76925997299|rigid:bisllY8hKGxUMJhzW7qh/C7/yiE	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9Y4F3	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-5235902|uniprotkb:A8MSK2|uniprotkb:B2RNX2|uniprotkb:B4DYY9|uniprotkb:B7ZMG1|uniprotkb:B7ZMG2|uniprotkb:Q6P1R6|uniprotkb:Q8WYR2|uniprotkb:Q9Y4J9|uniprotkb:F8VV09|intact:EBI-28974195|ensembl:ENSP00000379654|ensembl:ENSP00000479383	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:marf1_human(display_long)|uniprotkb:MARF1(gene name)|psi-mi:MARF1(display_short)|uniprotkb:KIAA0430(gene name synonym)|uniprotkb:LKAP(gene name synonym)|uniprotkb:Limkain-b1(gene name synonym)|uniprotkb:Meiosis arrest female protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578418|imex:IM-24624-270	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSP00000379654|ensembl:ENST00000548025|ensembl:ENSP00000449376|ensembl:ENST00000551742|ensembl:ENSP00000450309|ensembl:ENSP00000479383|ensembl:ENST00000632465|ensembl:ENSP00000487685|ensembl:ENST00000632628|ensembl:ENSP00000488025|refseq:NP_001171927.1|refseq:NP_001171928.1|refseq:NP_055462.2|refseq:XP_016879390.1|refseq:XP_005255764.1|ensembl:ENSG00000166783(gene)|ensembl:ENSG00000277140(gene)|ensembl:ENST00000396368(transcript)|ensembl:ENST00000621511(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048477"(oogenesis)|go:"GO:1903231"(mRNA binding involved in posttranscriptional gene silencing)|go:"GO:1905762"(CCR4-NOT complex binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021139|interpro:IPR024582|interpro:IPR024768|interpro:IPR025605|interpro:IPR034189|interpro:IPR034191|interpro:IPR035979|interpro:IPR041966|rcsb pdb:2DGX|rcsb pdb:2DIU|rcsb pdb:6FDL	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:zID4F4+nboiYsfaiiF+SaERi81I9606	intact-crc:7F2AFA5095B9BDA3|rigid:yQZ4i+ZlxZtRsf/O074S0zKc7As	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q5VT52	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-372367|uniprotkb:O75048|uniprotkb:Q5VT53|uniprotkb:Q6MZL4|uniprotkb:Q86XD2|uniprotkb:A8K6N8|uniprotkb:B3KPT1|uniprotkb:Q5VT51|uniprotkb:Q9P0D7|uniprotkb:B4E2Q6|ensembl:ENSP00000358064	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:rprd2_human(display_long)|uniprotkb:RPRD2(gene name)|psi-mi:RPRD2(display_short)|uniprotkb:KIAA0460(gene name synonym)|uniprotkb:HSPC099(orf name)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578427|imex:IM-24624-271	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_056018.2|ensembl:ENSG00000163125(gene)|ensembl:ENST00000369068(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q5VT52|rcsb pdb:4FLB|reactome:R-HSA-6807505|refseq:NP_001284602.1|refseq:NP_001284603.1|dip:DIP-31155N	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:HbkwBBEJ+MNQOjJ2nezU7MJMHYQ9606	intact-crc:0CE09A4E654C0AB4|rigid:PHIxRVUeq05DQAQ86kzQM8lWZTw	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q8NEZ4	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578436|imex:IM-24624-272	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606	intact-crc:E0B5E8ECB65AAF56|rigid:aQDkxA05F3pIfMNU90G0A4SJadA	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q7Z3U7	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-358882|uniprotkb:A5D8U7|uniprotkb:A7E2Y0|uniprotkb:Q86TA2|uniprotkb:Q8N3I5|uniprotkb:Q8NAI0|uniprotkb:Q9UPW1|intact:EBI-2829603|intact:EBI-358896|uniprotkb:Q8NHE2|uniprotkb:B9EGP5|uniprotkb:F8VWA6|uniprotkb:F8W1Z6|intact:EBI-10962461|ensembl:ENSP00000377250	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:mon2_human(display_long)|uniprotkb:MON2(gene name)|psi-mi:MON2(display_short)|uniprotkb:KIAA1040(gene name synonym)|uniprotkb:SF21(gene name synonym)|uniprotkb:Protein SF21(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578445|imex:IM-24624-273	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001265399.1|refseq:NP_001265398.1|refseq:NP_055841.2|refseq:XP_016874530.1|ensembl:ENSG00000061987(gene)|ensembl:ENST00000393630(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026829|interpro:IPR032629|interpro:IPR032691|interpro:IPR032817|mint:Q7Z3U7	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:pEkENsLrswc7Cb2WTKZfQdESrtQ9606	intact-crc:B684BC0D2628DB17|rigid:msGCdfIQxd9ebIisSRsY0xmfQSY	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:O15164	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578454|imex:IM-24624-274	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)	-	-	-	figure legend:"Supplementary Table 1 (suite 7)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606	intact-crc:B87172BA038D4614|rigid:i6Cb+YafI8yj75eSD61wTvq0JN8	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6AYS7	uniprotkb:P49286	intact:EBI-11578469|uniprotkb:Q6PTT1|ensembl:ENSRNOP00000015852	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:acy1a_rat(display_long)|uniprotkb:ACY IA(gene name synonym)|uniprotkb:Acy1(gene name synonym)|uniprotkb:N-acyl-L-amino-acid amidohydrolase(gene name synonym)|uniprotkb:Acy1a(gene name)|psi-mi:Acy1a(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578474|imex:IM-24624-275	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005383.1|refseq:XP_006243777.1|refseq:XP_006243778.1|rgd:2030|ensembl:ENSRNOG00000011189(gene)|ensembl:ENSRNOT00000015851(transcript)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|interpro:IPR010159(N-acyl-L-amino-acid amidohydrolase)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR036264|reactome:R-RNO-5423646	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:Xp0pQ2Afk4gpftIZ2sT/Jnzb+ZE10116	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:812499BB48BC5DA1|rigid:xjn/KQzQv/gy7YuVVPcpkhWjJP8	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02759	uniprotkb:P49286	intact:EBI-11578487|uniprotkb:F1MA51|ensembl:ENSRNOP00000026038	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:lox15_rat(display_long)|uniprotkb:Arachidonate 15-lipoxygenase(gene name synonym)|uniprotkb:Hepoxilin A3 synthase Alox15(gene name synonym)|uniprotkb:Linoleate 13S-lipoxygenase(gene name synonym)|uniprotkb:12/15-lipoxygenase(gene name synonym)|uniprotkb:Alox12l(gene name synonym)|uniprotkb:Arachidonate 12-lipoxygenase, leukocyte-type(gene name synonym)|uniprotkb:Arachidonate omega-6 lipoxygenase(gene name synonym)|uniprotkb:Alox15(gene name)|psi-mi:Alox15(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578483|imex:IM-24624-276	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112272.2|rgd:70493|ensembl:ENSRNOG00000019183(gene)|ensembl:ENSRNOT00000026038(transcript)|go:"GO:0001503"(ossification)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0004052"("arachidonate 12(S)-lipoxygenase activity")|go:"GO:0005506"(iron ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016165"(linoleate 13S-lipoxygenase activity)|go:"GO:0016702"(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0030282"(bone mineralization)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034440"(lipid oxidation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035358"(regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035963"(cellular response to interleukin-13)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046456"(icosanoid biosynthetic process)|go:"GO:0047977"(hepoxilin-epoxide hydrolase activity)|go:"GO:0050473"(arachidonate 15-lipoxygenase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051120"(hepoxilin A3 synthase activity)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901074"(regulation of engulfment of apoptotic cell)|go:"GO:2001303"(lipoxin A4 biosynthetic process)|interpro:IPR000907(Lipoxygenase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001885(Lipoxygenase, mammalian)|interpro:IPR013819(Lipoxygenase, C-terminal)|interpro:IPR020833|interpro:IPR020834|interpro:IPR036226|interpro:IPR036392|interpro:IPR042062|reactome:R-RNO-2142691|reactome:R-RNO-2142712|reactome:R-RNO-2142770|reactome:R-RNO-9018677|reactome:R-RNO-9018681|reactome:R-RNO-9018896|reactome:R-RNO-9023661|reactome:R-RNO-9025106|reactome:R-RNO-9026286	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:w+XUKCcgAwiY2lY9mWMV5+uZCBg10116	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:53599641F97BA8A0|rigid:Tqmc6t7xt9/3PyA8KnsbojJT1t8	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62944	uniprotkb:P49286	intact:EBI-7048246|ensembl:ENSRNOP00000072290|uniprotkb:P21851|intact:MINT-122517	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:ap2b1_rat(display_long)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578497|imex:IM-24624-277	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008766157.1|refseq:XP_008766158.1|refseq:XP_008766159.1|refseq:XP_008766160.1|refseq:XP_008766161.1|ensembl:ENSRNOG00000061543(gene)|ensembl:ENSRNOT00000085799(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030118"(clathrin coat)|go:"GO:0030119"(AP-type membrane coat adaptor complex)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035904"(aorta development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099590"(neurotransmitter receptor internalization)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905477"(positive regulation of protein localization to membrane)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:P62944|rcsb pdb:3H1Z|rcsb pdb:3HS9|rcsb pdb:6OWT|reactome:R-RNO-177504|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|go:"GO:0072583"(clathrin-dependent endocytosis)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|refseq:XP_017452462.1|refseq:NP_542150.1|rgd:71048|dip:DIP-40944N	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	function:Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP2B1 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositides|comment:mint	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:Q5oFhdE1hcmqu7xLG3MteCu0Zcg10116	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:C1623F75C8948DBB|rigid:GZBUlHpEaCd6IBClAeOqy49H290	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O35413	uniprotkb:P49286	intact:EBI-7458031|uniprotkb:Q923T8|intact:MINT-1216268	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:srbs2_rat(display_long)|uniprotkb:Arg-binding protein 2(gene name synonym)|uniprotkb:Argbp2(gene name synonym)|uniprotkb:Arg/Abl-interacting protein 2(gene name synonym)|uniprotkb:Neural ArgBP2(gene name synonym)|uniprotkb:Sorbin(gene name synonym)|uniprotkb:Sorbs2(gene name)|psi-mi:Sorbs2(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578506|imex:IM-24624-278	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:O35413|interpro:IPR028506|interpro:IPR036028|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|refseq:NP_446222.1|rgd:620061|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	comment:mint	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:PPlOlF5Zo+yeGF3p4kxWBpCtE3w10116	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:B4E6E28F9767CDF3|rigid:rPSV6tWZqV6+siOKiDq/AAfx+to	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:B2DD29	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11578515|uniprotkb:F1M6Y8|ensembl:ENSRNOP00000033679	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:brsk1_rat(display_long)|uniprotkb:Brain-specific serine/threonine-protein kinase 1(gene name synonym)|uniprotkb:Sadb(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAD-B(gene name synonym)|uniprotkb:Brsk1(gene name)|psi-mi:Brsk1(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578520|imex:IM-24624-279	author score:C	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001120809.1|rgd:1563268|go:"GO:0099504"(synaptic vesicle cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150034"(distal axon)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|ensembl:ENSRNOG00000017673(gene)|ensembl:ENSRNOT00000031172(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008306"(associative learning)|go:"GO:0009411"(response to UV)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051298"(centrosome duplication)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:JWb75axrMPqmdpX/npr8RFxQEu410116	intact-crc:D8A7AF46963445FA|rigid:8AIfQKYFj6p1xqgWvFHKlnN7RkM	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:D3ZML2	uniprotkb:P49286	intact:EBI-11578529|uniprotkb:Q4A1P4|uniprotkb:E9PTC7	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:brsk2_rat(display_long)|uniprotkb:Brain-specific serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Sada(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAD-A(gene name synonym)|uniprotkb:Brsk2(gene name)|psi-mi:Brsk2(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578535|imex:IM-24624-280	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rgd:1566256|go:"GO:0150034"(distal axon)|go:"GO:0106311"|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007409"(axonogenesis)|go:"GO:0009411"(response to UV)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0006887"(exocytosis)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:ytb1F7fBNyw34jtuvyo1R81r97s10116	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:BDECB9ED583D30AE|rigid:S3/g7GsZmsXp6m0+xOCKyeFhTVs	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q5U302	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-920749|ensembl:ENSRNOP00000008041	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:q5u302_rat(display_long)|uniprotkb:Ctnna1(gene name)|psi-mi:Ctnna1(display_short)|uniprotkb:Catna1(gene name synonym)|uniprotkb:rCG_49560(orf name)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578544|imex:IM-24624-281	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	rgd:1359485|refseq:NP_001007146.1|ensembl:ENSRNOG00000005796(gene)|ensembl:ENSRNOT00000008041(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|reactome:R-RNO-418990|reactome:R-RNO-5218920|reactome:R-RNO-525793|reactome:R-RNO-5626467|refseq:XP_017456453.1	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:wB/6HwVE3/evEF7MZz8pBhRbrDU10116	intact-crc:C62686679AD717D4|rigid:iuAHespU4YgYSwY9CoistheW0tc	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:D4ABM3	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11578553|ensembl:ENSRNOP00000005846	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:d4abm3_rat(display_long)|uniprotkb:Daam1_predicted(gene name synonym)|uniprotkb:rCG_61929(orf name)|uniprotkb:Daam1(gene name)|psi-mi:Daam1(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578557|imex:IM-24624-282	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001101500.1|rgd:1305119|ensembl:ENSRNOG00000004345(gene)|ensembl:ENSRNOT00000005846(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031514"(motile cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR042201|reactome:R-RNO-4086400|reactome:R-RNO-5663220|reactome:R-RNO-8980692|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:EnYrLkYieH3OlHEipRsgpl1kOBE10116	intact-crc:BA089E208EB00EF0|rigid:yLyE3m81v/znkwPtox0f4vpGcCY	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q3ZAV8	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11578579|ensembl:ENSRNOP00000033608	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:edc4_rat(display_long)|uniprotkb:Edc4(gene name)|psi-mi:Edc4(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578575|imex:IM-24624-284	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001028240.3|rgd:1562009|ensembl:ENSRNOG00000024025(gene)|ensembl:ENSRNOT00000030967(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|interpro:IPR036322|reactome:R-RNO-430039	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:fqgVQh5udHEDkZgIz+aBFdBQ86g10116	intact-crc:E15D868B4814EE9E|rigid:nMlcZs+6Gp7FAA+l+GPAGsLGT5E	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P38650	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-349489|uniprotkb:Q63178	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:dyhc1_rat(display_long)|uniprotkb:Dync1h1(gene name)|psi-mi:Dync1h1(display_short)|uniprotkb:Dnch1(gene name synonym)|uniprotkb:Dnec1(gene name synonym)|uniprotkb:Map1c(gene name synonym)|uniprotkb:Dhc1(gene name synonym)|uniprotkb:Dyhc(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)|uniprotkb:MAP 1C(gene name synonym)|uniprotkb:Dnchc1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578566|imex:IM-24624-283	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	rgd:2511|refseq:NP_062099.3|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR024317|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024743|go:"GO:0005737"(cytoplasm)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002177"(manchette)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007286"(spermatid development)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043025"(neuronal cell body)|go:"GO:0033962"(P-body assembly)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|reactome:R-RNO-141444|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-5663220|reactome:R-RNO-6798695|reactome:R-RNO-6807878|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8854518|reactome:R-RNO-9646399|reactome:R-RNO-9648025|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR027417|mint:P38650|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|interpro:IPR043157|interpro:IPR043160	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:RxE6eIUsLysOcDObdE+E7cBOC5w10116	intact-crc:DEF0AA9CB6BA0D48|rigid:KCHbqrXZPSSiNxrDkEWbYjDnMi8	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P18265	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-8759234|ensembl:ENSRNOP00000027677	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:gsk3a_rat(display_long)|uniprotkb:Gsk3a(gene name)|psi-mi:Gsk3a(display_short)|uniprotkb:Factor A(gene name synonym)|uniprotkb:Serine/threonine-protein kinase GSK3A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578602|imex:IM-24624-286	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	rgd:620351|refseq:NP_059040.1|ensembl:ENSRNOG00000020417(gene)|ensembl:ENSRNOT00000027677(transcript)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071879"(positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904227"(negative regulation of glycogen synthase activity, transferring glucose-1-phosphate)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2000467"("positive regulation of glycogen (starch) synthase activity")|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:d51LNk4nVFN7W1f78hrMlfzwiU410116	intact-crc:4B9A47C195421A6B|rigid:E97YhTNQkSyKGB/2Or+0i26OXaw	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q1RP76	uniprotkb:P49286	intact:EBI-11578589	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:q1rp76_rat(display_long)|uniprotkb:ZH8(gene name synonym)|uniprotkb:Eif4g2(gene name)|psi-mi:Eif4g2(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578593|imex:IM-24624-285	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001017374.2|rgd:1305294|interpro:IPR016021(MIF4-like, type 1/2/3)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007507"(heart development)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0060999"(positive regulation of dendritic spine development)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:SK5MjcmTsNHp8VQjI7+Kpy50Eao10116	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:385C6146B0F8934A|rigid:9vzF8fcEGTqv9B7/8l5acE7g9LU	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:F1LP64	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11578615|uniprotkb:Q5I0I0|uniprotkb:Q497C1|uniprotkb:F1LP79|ensembl:ENSRNOP00000076130	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:tripc_rat(display_long)|uniprotkb:Thyroid receptor-interacting protein 12(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase TRIP12(gene name synonym)|uniprotkb:Trip12(gene name)|psi-mi:Trip12(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578611|imex:IM-24624-287	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001026829.2|rgd:1306607|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018123|interpro:IPR035983|interpro:IPR037197|reactome:R-RNO-983168|go:"GO:0005654"(nucleoplasm)|ensembl:ENSRNOG00000016963(gene)|ensembl:ENSRNOT00000093245(transcript)|go:"GO:0000209"(protein polyubiquitination)	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:rekaD7psfszpGUmjoiTvb5qsAkg10116	intact-crc:29582348E1690C89|rigid:2ABewoXoY64n9K8KouYrlKwhWUs	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9QY78	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-1812464	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ikkb_rat(display_long)|uniprotkb:Ikbkb(gene name)|psi-mi:Ikbkb(display_short)|uniprotkb:Ikkb(gene name synonym)|uniprotkb:I-kappa-B kinase 2(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase beta(gene name synonym)|uniprotkb:Serine/threonine protein kinase IKBKB(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578629|imex:IM-24624-288	author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	rgd:621375|refseq:NP_445807.2|interpro:IPR022007|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR041185|reactome:R-RNO-1169091|reactome:R-RNO-168638|reactome:R-RNO-1810476|reactome:R-RNO-202424|reactome:R-RNO-209543|reactome:R-RNO-209560|reactome:R-RNO-2871837|reactome:R-RNO-445989|reactome:R-RNO-5357905|reactome:R-RNO-5357956|reactome:R-RNO-5607764|reactome:R-RNO-9020702|reactome:R-RNO-933542|reactome:R-RNO-937039|reactome:R-RNO-975144|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:2001259"(positive regulation of cation channel activity)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:AoBNUblwig3qhH01LheG2gC+qnc10116	intact-crc:B52531E597D42764|rigid:doloBMgFVBnO56Jz6moSprhxOYA	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q99J82	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-919744|ensembl:ENSRNOP00000025906	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ilk_rat(display_long)|uniprotkb:Ilk(gene name)|psi-mi:Ilk(display_short)|uniprotkb:59 kDa serine/threonine-protein kinase(gene name synonym)|uniprotkb:Beta-integrin-linked kinase(gene name synonym)|uniprotkb:ILK-1(gene name synonym)|uniprotkb:ILK-2(gene name synonym)|uniprotkb:ILK1(gene name synonym)|uniprotkb:ILK2(gene name synonym)|uniprotkb:p59ILK(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578638|imex:IM-24624-289	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	rgd:620063|refseq:NP_596900.1|ensembl:ENSRNOG00000018993(gene)|ensembl:ENSRNOT00000025906(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007569"(cell aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010761"(fibroblast migration)|go:"GO:0014044"(Schwann cell development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021675"(nerve development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032288"(myelin assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR035692|interpro:IPR036770|reactome:R-RNO-446343|reactome:R-RNO-446353	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:9kMagkwUrtq1XaI+9PXPJ21hHY810116	intact-crc:C796266F2166E76F|rigid:An9xW51JhLGJj9CCB39DyQy6Ydg	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:D4A857	uniprotkb:P49286	intact:EBI-11578647|intact:EBI-11702583|ensembl:ENSRNOP00000011105	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:d4a857_rat(display_long)|uniprotkb:Ipo9_predicted(gene name synonym)|uniprotkb:rCG_46187(orf name)|uniprotkb:Ipo9(gene name)|psi-mi:Ipo9(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578652|imex:IM-24624-290	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001100650.1|rgd:1310537|ensembl:ENSRNOG00000007418(gene)|ensembl:ENSRNOT00000011105(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0006606"(protein import into nucleus)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:m+JTm/L/wzzR7A+qtgQcXv5hDk410116	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:53263A6B4B8DDCAC|rigid:xqSmK29DzR0SumIsQAzb/5beWb0	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:D4A510	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11578675|ensembl:ENSRNOP00000028244	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:d4a510_rat(display_long)|uniprotkb:Smarcc2(gene name)|psi-mi:Smarcc2(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578680|imex:IM-24624-292	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:XP_001055673.1|rgd:1597704|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|go:"GO:0003682"(chromatin binding)|ensembl:ENSRNOG00000031135(gene)|ensembl:ENSRNOT00000028244(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|reactome:R-RNO-3214858|reactome:R-RNO-8939243|interpro:IPR017930	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:oDTrkYuBl1cFjeZvrbqeJJ6Irr010116	intact-crc:0F595F4D965341CA|rigid:QrGb7SM2up2LsW5RNoRMMCcXhvY	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q6DGF2	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11578665|uniprotkb:D4A4G6|ensembl:ENSRNOP00000030596	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:q6dgf2_rat(display_long)|uniprotkb:Enth(gene name synonym)|uniprotkb:Clint1(gene name)|psi-mi:Clint1(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578661|imex:IM-24624-291	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001002022.1|rgd:1303328|ensembl:ENSRNOG00000005406(gene)|ensembl:ENSRNOT00000035346(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048268"(clathrin coat assembly)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030544	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:Vy74YHkMZJdyKNZ2AFVzTmL2+xw10116	intact-crc:CE8DEAE92A321D06|rigid:8000+qP0wj1diHfkJ8X3ZnY0H90	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5U2Z3	uniprotkb:P49286	intact:EBI-1638243|ensembl:ENSRNOP00000075200	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:np1l4_rat(display_long)|uniprotkb:Nap1l4(gene name)|psi-mi:Nap1l4(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578698|imex:IM-24624-294	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1305391|refseq:NP_001012170.1|refseq:XP_006230885.1|refseq:XP_006230886.1|ensembl:ENSRNOG00000020615(gene)|ensembl:ENSRNOT00000087961(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0030425"(dendrite)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0043025"(neuronal cell body)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:B3TegSNdEowZ8YLv2eo4CiSwhPM10116	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:B357911DF9503663|rigid:4U4mTIeoYuffT5rPt6LOA+cy3oE	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99068	uniprotkb:P49286	intact:EBI-919734|uniprotkb:Q4FZX8|uniprotkb:Q642A1|uniprotkb:Q64723|ensembl:ENSRNOP00000012665	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:amrp_rat(display_long)|uniprotkb:Lrpap1(gene name)|psi-mi:Lrpap1(display_short)|uniprotkb:Low density lipoprotein receptor-related protein-associated protein 1(gene name synonym)|uniprotkb:Gp330-binding 45 kDa protein(gene name synonym)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578689|imex:IM-24624-293	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:620700|refseq:NP_001162584.1|ensembl:ENSRNOG00000009313(gene)|ensembl:ENSRNOT00000012665(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0012505"(endomembrane system)|go:"GO:0031904"(endosome lumen)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035473"(lipase binding)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048237"(rough endoplasmic reticulum lumen)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|interpro:IPR009066(Alpha-2-macroglobulin receptor-associated protein, domain 1)|interpro:IPR010483(Alpha-2-macroglobulin RAP, C-terminal)|interpro:IPR036744|interpro:IPR037999|interpro:IPR038001|interpro:IPR038003|mint:Q99068	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:iCszi7bhiu3sGLgNv5dSIQ81m5Q10116	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:0FF50B971ABBBDE1|rigid:EMcpCi8c5433n6g9Ot23gEcd6HI	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9EPI6	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-6899705|uniprotkb:Q5PPF6|uniprotkb:Q7TSC6|uniprotkb:Q7TSC8|uniprotkb:Q9EPI4|uniprotkb:Q9EPI5	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:nsmf_rat(display_long)|uniprotkb:Nsmf(gene name)|psi-mi:Nsmf(display_short)|uniprotkb:Jac(gene name synonym)|uniprotkb:Nelf(gene name synonym)|uniprotkb:Juxtasynaptic attractor of caldendrin on dendritic boutons protein(gene name synonym)|uniprotkb:Nasal embryonic luteinizing hormone-releasing hormone factor(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578707|imex:IM-24624-295	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0005886"(plasma membrane)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:0097440"(apical dendrite)|mint:Q9EPI6|interpro:IPR033374|rgd:619819|refseq:NP_001257555.1|refseq:NP_001257556.1|refseq:NP_001257557.1|refseq:NP_476538.2	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:7roymdKtL+QSCC6O/qfhzsLvSaA10116	intact-crc:6E8E2100622F4C6C|rigid:tB/ky5xJAXAcuitggDEdu+SEVBY	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:D3ZS72	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11578720|ensembl:ENSRNOP00000009517	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:d3zs72_rat(display_long)|uniprotkb:Prex1(gene name)|psi-mi:Prex1(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578716|imex:IM-24624-296	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	rgd:1306534|ensembl:ENSRNOG00000006952(gene)|ensembl:ENSRNOT00000009517(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR036388|interpro:IPR036034|interpro:IPR036390|reactome:R-RNO-193648|reactome:R-RNO-416482|reactome:R-RNO-8980692|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013404|reactome:R-RNO-9013406|reactome:R-RNO-9013408|reactome:R-RNO-9013409|reactome:R-RNO-9013423	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:TNG3zAkQnawBFfeF6jHQyN7l+tc10116	intact-crc:92DE8A51884AC83A|rigid:5fWXB3xesiuf4c2OX/mzJO8IaII	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:P35355	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11578734|uniprotkb:Q925V4|uniprotkb:Q64379|ensembl:ENSRNOP00000003567	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:pgh2_rat(display_long)|uniprotkb:Cox-2(gene name synonym)|uniprotkb:Cox2(gene name synonym)|uniprotkb:Cyclooxygenase-2(gene name synonym)|uniprotkb:PHS II(gene name synonym)|uniprotkb:Prostaglandin H2 synthase 2(gene name synonym)|uniprotkb:Prostaglandin-endoperoxide synthase 2(gene name synonym)|uniprotkb:Ptgs2(gene name)|psi-mi:Ptgs2(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578730|imex:IM-24624-297	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_058928.3|rgd:620349|reactome:R-RNO-9027604|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033280"(response to vitamin D)|go:"GO:0034097"(response to cytokine)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042633"(hair cycle)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046697"(decidualization)|go:"GO:0046872"(metal ion binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|ensembl:ENSRNOG00000002525(gene)|ensembl:ENSRNOT00000003567(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001525"(angiogenesis)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004666"(prostaglandin-endoperoxide synthase activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007566"(embryo implantation)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071284"(cellular response to lead ion)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071471"(cellular response to non-ionic osmotic stress)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090271"(positive regulation of fibroblast growth factor production)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0090362"(positive regulation of platelet-derived growth factor production)|go:"GO:0150077"(regulation of neuroinflammatory response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019791|interpro:IPR029576|interpro:IPR037120|reactome:R-RNO-197264|reactome:R-RNO-2142770|reactome:R-RNO-2162123|reactome:R-RNO-9018677|reactome:R-RNO-9018679|reactome:R-RNO-9025094|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0007613"(memory)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009750"(response to fructose)|go:"GO:0010033"(response to organic substance)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016702"(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030728"(ovulation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031622"(positive regulation of fever generation)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:TrShpSuKhLl/BAx7bPMVkjacVOw10116	intact-crc:A680E9D3759735FC|rigid:9t2DTtiVydBUrrH4eUX/A+vmYqE	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q2TL32	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11578749|uniprotkb:Q5BJM4	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ubr4_rat(display_long)|uniprotkb:RING-type E3 ubiquitin transferase UBR4(gene name synonym)|uniprotkb:N-recognin-4(gene name synonym)|uniprotkb:Rbaf600(gene name synonym)|uniprotkb:Zinc finger UBR1-type protein 1(gene name synonym)|uniprotkb:Zubr1(gene name synonym)|uniprotkb:Ubr4(gene name)|psi-mi:Ubr4(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578745|imex:IM-24624-298	author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR036322|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025704|refseq:NP_001034115.1|rgd:1563121|reactome:R-RNO-6798695|reactome:R-RNO-983168|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:4SVsaGnMhdh7BT24qYQECoV8I+E10116	intact-crc:EA7FA8E2D47E64AE|rigid:xe6kanZZwTarIly9LypPOMW9UA0	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:F1LMI7	uniprotkb:P49286	intact:EBI-11578768|ensembl:ENSRNOP00000041545	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:f1lmi7_rat(display_long)|uniprotkb:Rnf123(gene name)|psi-mi:Rnf123(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578764|imex:IM-24624-299	author score:B	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001178509.1|refseq:XP_006243753.1|refseq:XP_006243754.1|refseq:XP_006243755.1|refseq:XP_006243756.1|refseq:XP_006243757.1|refseq:XP_006243758.1|refseq:XP_006243759.1|rgd:2301394|ensembl:ENSRNOG00000033378(gene)|ensembl:ENSRNOT00000043825(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035773|interpro:IPR043136	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:CthYr6eoeZC7vyb8Lqs5eLzLlNs10116	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:BBCC5A6835E53754|rigid:YYKAb6gC5515mZf+FStUYzwsHfU	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9Z2Q1	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-920344|uniprotkb:Q5RKK4	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:sc31a_rat(display_long)|uniprotkb:Sec31a(gene name)|psi-mi:Sec31a(display_short)|uniprotkb:Sec31l1(gene name synonym)|uniprotkb:SEC31-related protein A(gene name synonym)|uniprotkb:SEC31-like protein 1(gene name synonym)|uniprotkb:Vesicle-associated protein 1(gene name synonym)|uniprotkb:Vap1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578778|imex:IM-24624-300	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR024298|reactome:R-RNO-204005|reactome:R-RNO-2132295|reactome:R-RNO-983170|rgd:620233|refseq:NP_148981.1|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|refseq:XP_006250751.1|refseq:XP_006250752.1|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0030120"(vesicle coat)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR036322|interpro:IPR040251	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:IzsvmogIewqxkqnGIDVhk+z7vP010116	intact-crc:278601028BA5DA34|rigid:F2p7Q/8dEHzLe5croAnp+u97Qjg	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q9JJP9	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11578804|uniprotkb:Q6IN34	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ubql1_rat(display_long)|uniprotkb:Da41(gene name synonym)|uniprotkb:Plic1(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:Ubqln1(gene name)|psi-mi:Ubqln1(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578800|imex:IM-24624-302	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|rcsb pdb:1KJV|refseq:NP_446199.2|rgd:620745|reactome:R-RNO-8856825|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034140"(negative regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR028430	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:SlFxpY0vAJey1F8obSLmJZwlz4Q10116	intact-crc:243DD355F6597A81|rigid:eMsR7u1P8DJ0jgfEAcmnf+FgU8U	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:D3ZER6	uniprotkb:P49286	intact:EBI-11578787|ensembl:ENSRNOP00000005571	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:d3zer6_rat(display_long)|uniprotkb:Tnpo2_predicted(gene name synonym)|uniprotkb:rCG_51621(orf name)|uniprotkb:Tnpo2(gene name)|psi-mi:Tnpo2(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578791|imex:IM-24624-301	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001100636.1|rgd:1310356|ensembl:ENSRNOG00000003970(gene)|ensembl:ENSRNOT00000005571(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:ucyftw9qLkv0iVc8NlcX4w90OCc10116	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:0D7F7F322F372315|rigid:FKxd2AdIM2vnY63dLzuqlUxzIO0	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:D5MTG9	uniprotkb:P49286	intact:EBI-11578827	intact:EBI-1188341|ensembl:ENSP00000257068	psi-mi:d5mtg9_rat(display_long)|uniprotkb:RGD1562326(gene name synonym)|uniprotkb:UBR1(gene name synonym)|uniprotkb:Ubr1(gene name)|psi-mi:Ubr1(display_short)	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578832|imex:IM-24624-304	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR039164|interpro:IPR036390|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR003769(Adaptor protein ClpS, core)|interpro:IPR014719(Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like)|refseq:NP_001171543.1|rgd:1562326|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000502"(proteasome complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070728"(leucine binding)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR044046	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:e838Qxrnk01z+afLnC8Q1XviqnA10116	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	intact-crc:61CE28B6FD9A9729|rigid:eIbOpB0GgHc+av9Ujbm8bMnaT8w	false	-	sufficient binding region:308-362	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:D4AA63	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11578818|ensembl:ENSRNOP00000026214	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:d4aa63_rat(display_long)|uniprotkb:Ubqln2_predicted(gene name synonym)|uniprotkb:rCG_38924(orf name)|uniprotkb:Ubqln2(gene name)|psi-mi:Ubqln2(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578814|imex:IM-24624-303	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001101721.1|rgd:1563566|ensembl:ENSRNOG00000003099(gene)|ensembl:ENSRNOT00000026214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904021"(negative regulation of G protein-coupled receptor internalization)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028430|interpro:IPR029071|reactome:R-RNO-8856825	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:8mZMnEcciAcDQyiDj1+1Zd+VeBk10116	intact-crc:237D6E6663373F6A|rigid:kVEzWAsYlOo3kN1ystCM1tMOfiE	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q62671	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11578845|uniprotkb:F1LRS0	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:ubr5_rat(display_long)|uniprotkb:100 kDa protein(gene name synonym)|uniprotkb:Dd5(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Edd(gene name synonym)|uniprotkb:Edd1(gene name synonym)|uniprotkb:Hyd(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym)|uniprotkb:Ubr5(gene name)|psi-mi:Ubr5(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578841|imex:IM-24624-305	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR035983|interpro:IPR036053|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|rcsb pdb:3NTW|rgd:621236|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:82CckHCS4Ox0vZTISFtDiDcUlDA10116	intact-crc:EC5DE0AF3750BEE7|rigid:MdNs50vXHtKsqu/dTfBepslBGNQ	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:D3ZZ62	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11578861|ensembl:ENSRNOP00000009645	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:d3zz62_rat(display_long)|uniprotkb:Xpot_predicted(gene name synonym)|uniprotkb:Xpot(gene name)|psi-mi:Xpot(display_short)|uniprotkb:rCG_48839(orf name)|uniprotkb:"Exportin(tRNA)"(gene name synonym)|uniprotkb:tRNA exportin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578857|imex:IM-24624-306	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	refseq:NP_001101572.1|rgd:1305562|ensembl:ENSRNOG00000007088(gene)|ensembl:ENSRNOT00000009645(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031267"(small GTPase binding)|go:"GO:0071528"(tRNA re-export from nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040017	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:uEwBmMDN92yqVfc7Sa/Ql6DWC/g10116	intact-crc:85D1937E2871C5B8|rigid:xscfhVqaBAFrxFtO1YTXRwOszj4	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49286	uniprotkb:Q6XDA0	intact:EBI-1188341|ensembl:ENSP00000257068	intact:EBI-11578874|uniprotkb:F1MAL3	psi-mi:mtr1b_human(display_long)|uniprotkb:MTNR1B(gene name)|psi-mi:MTNR1B(display_short)	psi-mi:q6xda0_rat(display_long)|uniprotkb:LOC314251(gene name synonym)|uniprotkb:Sptb(gene name)|psi-mi:Sptb(display_short)	psi-mi:"MI:0018"(two hybrid)	Benleulmi-Chaachoua et al. (2015)	pubmed:26514267|imex:IM-24624	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11578870|imex:IM-24624-307	author score:D	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005950.1|refseq:XP_011541141.1|ensembl:ENSG00000134640(gene)|ensembl:ENST00000257068(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002278(Melatonin receptor type 1A)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|reactome:R-HSA-373076|reactome:R-HSA-418594	interpro:IPR018159|refseq:NP_997687.1|rgd:1303243|interpro:IPR036872|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR016343(Spectrin, beta subunit)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0008091"(spectrin)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)	-	-	-	figure legend:"Supplementary Table 1 (suite 8)"|author-confidence:D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/09/22	2016/02/11	rogid:rswnP00xD/7eXbqSz67qJEOHGXU9606	rogid:eNNUdDJUXj7omTrP92Au8w0qUvw10116	intact-crc:435EF1FAAF6DC0D0|rigid:poLVpoLU6p6gLu+jiiXxnwoVoQw	false	sufficient binding region:308-362	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)