#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P18776	uniprotkb:P18775	intact:EBI-1120825|uniprotkb:P77745|ensemblbacteria:AAC73981|ensemblbacteria:BAA35627	intact:EBI-4411104|ensemblbacteria:AAC73980|ensemblbacteria:BAA35626	psi-mi:dmsb_ecoli(display_long)|uniprotkb:DMSO reductase iron-sulfur subunit(gene name synonym)|uniprotkb:dmsB(gene name)|psi-mi:dmsB(display_short)|uniprotkb:b0895(locus name)|uniprotkb:JW0878(locus name)	psi-mi:dmsa_ecoli(display_long)|uniprotkb:dmsA(gene name)|psi-mi:dmsA(display_short)|uniprotkb:b0894(locus name)|uniprotkb:JW5118(locus name)	psi-mi:"MI:0226"(ion exchange chromatography)	Sambasivarao et al. (1991)	imex:IM-25400|pubmed:1917829	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11464398|imex:IM-25400-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000213098.1|ensemblbacteria:AAC73981(transcript)|ensemblbacteria:b0895(gene)|ensemblbacteria:BAA35627(gene)|ensemblbacteria:BAA35627(transcript)|go:"GO:0009061"(anaerobic respiration)|go:"GO:0009389"(dimethyl sulfoxide reductase activity)|go:"GO:0009390"(dimethyl sulfoxide reductase complex)|go:"GO:0031237"(intrinsic component of periplasmic side of plasma membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR014297(Dimethylsulphoxide reductase, chain B)|interpro:IPR017896|interpro:IPR017900|refseq:NP_415415.1|dip:DIP-9453N	refseq:WP_000850303.1|refseq:NP_415414.4|dip:DIP-9452N|ensemblbacteria:AAC73980(transcript)|ensemblbacteria:b0894(gene)|ensemblbacteria:BAA35626(gene)|ensemblbacteria:BAA35626(transcript)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009061"(anaerobic respiration)|go:"GO:0009389"(dimethyl sulfoxide reductase activity)|go:"GO:0009390"(dimethyl sulfoxide reductase complex)|go:"GO:0030151"(molybdenum ion binding)|go:"GO:0031237"(intrinsic component of periplasmic side of plasma membrane)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR006655(Molybdopterin oxidoreductase, prokaryotic, conserved site)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR011888(Anaerobic dimethyl sulphoxide reductase, subunit A, DmsA/YnfE)|interpro:IPR019546|interpro:IPR027467|go:"GO:0030288"(outer membrane-bounded periplasmic space)	-	-	-	figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2015/12/11	2015/12/11	rogid:jruvDxiCwOaulc/CA+N/AiIFdKk83333	rogid:BqDY+FHsKi9VZGN1kVaKzJ5uuIA83333	rigid:i1rRaMczf7a75Ui/lPApXpt6L/g	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:28262"	intenz:1.8.5.3	intact:EBI-11791511|chebi:"CHEBI:42138"|chebi:"CHEBI:4612"|chebi:"CHEBI:23801"	intact:EBI-11464404	psi-mi:dimethyl sulfoxide(display_short)|psi-mi:"CHEBI:28262"(display_long)|intact:"(CH3)2SO"(synonym)|intact:Dimethyl sulfoxide(synonym)|intact:DIMETHYL SULFOXIDE(synonym)|intact:dimethyl sulfoxide(synonym)|intact:dimethyl sulfur oxide(synonym)|intact:dimethyl sulphoxide(synonym)|intact:dimethyli sulfoxidum(synonym)|intact:Dimethylsulfoxid(synonym)|intact:dimethylsulfoxyde(synonym)|intact:dimetil sulfoxido(synonym)|intact:DMSO(synonym)|intact:dmso(synonym)|intact:methylsulfinylmethane(synonym)|intact:"S(O)Me2"(synonym)|intact:"sulfinylbis(methane)"(synonym)|intact:"(methanesulfinyl)methane"(iupac name)|intact:dimethyl sulfoxide(iupac name)	psi-mi:dmsabc_ecoli(display_short)|psi-mi:1.8.5.3(display_long)|intact:DMSOR complex(complex synonym)|intact:Dimethylsulfoxide reductase complex(complex synonym)|intact:DmaABC DMSO reductase complex(complex recommended name)|intact:"dmsA:dmsB:dmsC"(complex systematic name)	psi-mi:"MI:0979"(oxidoreductase assay)	Sambasivarao et al. (1991)	imex:IM-25400|pubmed:1917829	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11791536|imex:IM-25400-2	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:1302"(stable complex)	-	evidence ontology:"ECO:0000353"|go:"GO:0016672"(oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0018907"(dimethyl sulfoxide metabolic process)|go:"GO:0009389"(dimethyl sulfoxide reductase activity)|go:"GO:0019645"(anaerobic electron transport chain)|intact:EBI-11464462(exp-evidence)|go:"GO:0048038"(quinone binding)|go:"GO:0009390"(dimethyl sulfoxide reductase complex)|complex portal:CPX-320(complex-primary)	go:"GO:0016672"(oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor)	-	curated-complex:"Terminal reductase required for the reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS) and that of a broad array of S- and N-oxide compounds during anaerobic growth. Induced in the presence of fumarate. The expression of the enzyme is dependent on molybdenum."|complex-properties:"Trimeric enzyme localised to the cytoplasmic membrane, with two extrinsic subunits (dmsA and dmsB) and one membrane anchor (dmsC)."|complex-assembly:Heterotrimer	figure legend:Table 3, Table 5, Fig. 6|comment:Relatively weak activity was demonstrated when methyl-violet was the electron donor, stronger activity when DMNH2 was the donor molecule.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/12/11	2016/06/29	-	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15724"	intenz:1.8.5.3	intact:EBI-11791541|chebi:"CHEBI:9733"|chebi:"CHEBI:15263"|chebi:"CHEBI:15262"|chebi:"CHEBI:27126"	intact:EBI-11464404	psi-mi:trimethylamine n-oxide(display_short)|psi-mi:"CHEBI:15724"(display_long)|intact:"(CH3)3NO"(synonym)|intact:"Me3N(+)O(-)"(synonym)|intact:"Me3N(O)"(synonym)|intact:"N(CH3)3O"(synonym)|intact:TMAO(synonym)|intact:Trimethylamine N-oxide(synonym)|intact:trimethylamine N-oxide(synonym)|intact:trimethylamine oxide(synonym)|intact:Trimethylaminoxid(synonym)|intact:trimethyloxamine(synonym)|intact:N,N-dimethylmethanamine oxide(iupac name)	psi-mi:dmsabc_ecoli(display_short)|psi-mi:1.8.5.3(display_long)|intact:DMSOR complex(complex synonym)|intact:Dimethylsulfoxide reductase complex(complex synonym)|intact:DmaABC DMSO reductase complex(complex recommended name)|intact:"dmsA:dmsB:dmsC"(complex systematic name)	psi-mi:"MI:0979"(oxidoreductase assay)	Sambasivarao et al. (1991)	imex:IM-25400|pubmed:1917829	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11791558|imex:IM-25400-3	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:1302"(stable complex)	-	evidence ontology:"ECO:0000353"|go:"GO:0016672"(oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0018907"(dimethyl sulfoxide metabolic process)|go:"GO:0009389"(dimethyl sulfoxide reductase activity)|go:"GO:0019645"(anaerobic electron transport chain)|intact:EBI-11464462(exp-evidence)|go:"GO:0048038"(quinone binding)|go:"GO:0009390"(dimethyl sulfoxide reductase complex)|complex portal:CPX-320(complex-primary)	go:"GO:0016672"(oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor)	-	curated-complex:"Terminal reductase required for the reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS) and that of a broad array of S- and N-oxide compounds during anaerobic growth. Induced in the presence of fumarate. The expression of the enzyme is dependent on molybdenum."|complex-properties:"Trimeric enzyme localised to the cytoplasmic membrane, with two extrinsic subunits (dmsA and dmsB) and one membrane anchor (dmsC)."|complex-assembly:Heterotrimer	figure legend:Table 3, Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/12/11	2016/06/29	-	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)