#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q05941	uniprotkb:Q05941	intact:EBI-79422|uniprotkb:Q53YK2	intact:EBI-79422|uniprotkb:Q53YK2	psi-mi:acha7_rat(display_long)|uniprotkb:Chrna7(gene name)|psi-mi:Chrna7(display_short)|uniprotkb:Acra7(gene name synonym)	psi-mi:acha7_rat(display_long)|uniprotkb:Chrna7(gene name)|psi-mi:Chrna7(display_short)|uniprotkb:Acra7(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Drisdel et al. (2000)	pubmed:10627589|imex:IM-24071	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10767062|imex:IM-24071-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0060112"(generation of ovulation cycle rhythm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099065"(integral component of spine apparatus membrane)|go:"GO:0140059"(dendrite arborization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1905144"(response to acetylcholine)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905920"(positive regulation of CoA-transferase activity)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001988"(positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure)|go:"GO:0005216"(ion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006811"(ion transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007613"(memory)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007611"(learning or memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030673"(axolemma)|go:"GO:0032094"(response to food)|go:"GO:0030424"(axon)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0050893"(sensory processing)|go:"GO:0051117"(ATPase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|rgd:2348|reactome:R-RNO-629594|refseq:NP_036964.3|interpro:IPR036719|interpro:IPR036734	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0060112"(generation of ovulation cycle rhythm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099065"(integral component of spine apparatus membrane)|go:"GO:0140059"(dendrite arborization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1905144"(response to acetylcholine)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905920"(positive regulation of CoA-transferase activity)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001988"(positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure)|go:"GO:0005216"(ion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006811"(ion transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007613"(memory)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007611"(learning or memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030673"(axolemma)|go:"GO:0032094"(response to food)|go:"GO:0030424"(axon)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0050893"(sensory processing)|go:"GO:0051117"(ATPase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|rgd:2348|reactome:R-RNO-629594|refseq:NP_036964.3|interpro:IPR036719|interpro:IPR036734	-	-	-	figure legend:Fig. 2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells)	-	2015/04/21	2015/05/07	rogid:JMMrLrOpwsSACaDfzOCXTed3Y7M10116	rogid:JMMrLrOpwsSACaDfzOCXTed3Y7M10116	rigid:mM8vlrAuvJs1p4MC1OrbQ//w4r0	false	35s radiolabel:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P60615	uniprotkb:Q05941	intact:EBI-7516391|uniprotkb:Q9PRI6|uniprotkb:Q9YI07|uniprotkb:P01378|uniprotkb:Q9YGD1|uniprotkb:Q9YI11|uniprotkb:Q9YI06|intact:MINT-5223718|uniprotkb:Q9YI09|uniprotkb:Q9YI10|uniprotkb:Q9YI13|uniprotkb:Q9YI12	intact:EBI-79422|uniprotkb:Q53YK2	psi-mi:3l21a_bunmu(display_long)|uniprotkb:Long neurotoxin 1(gene name synonym)|uniprotkb:Alpha-bungarotoxin, isoform A31(gene name synonym)|uniprotkb:Alpha-elapitoxin-Bm2a(gene name synonym)	psi-mi:acha7_rat(display_long)|uniprotkb:Chrna7(gene name)|psi-mi:Chrna7(display_short)|uniprotkb:Acra7(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Drisdel et al. (2000)	pubmed:10627589|imex:IM-24071	taxid:8616(bunmu)|taxid:8616(Bungarus multicinctus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10767074|imex:IM-24071-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P60615|interpro:IPR035076|interpro:IPR018354|interpro:IPR003571(Snake toxin)|go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|rcsb pdb:1ABT|rcsb pdb:1BXP|rcsb pdb:1HAA|rcsb pdb:1HAJ|rcsb pdb:1HC9|rcsb pdb:1HOY|rcsb pdb:1IDG|rcsb pdb:1IDH|rcsb pdb:1IDI|rcsb pdb:1IDL|rcsb pdb:1IK8|rcsb pdb:1IKC|rcsb pdb:1JBD|rcsb pdb:1KC4|rcsb pdb:1KFH|rcsb pdb:1KL8|rcsb pdb:1L4W|rcsb pdb:1LJZ|rcsb pdb:1LK1|rcsb pdb:1RGJ|rcsb pdb:2ABX|rcsb pdb:2BTX|rcsb pdb:6UWZ	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0060112"(generation of ovulation cycle rhythm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099065"(integral component of spine apparatus membrane)|go:"GO:0140059"(dendrite arborization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1905144"(response to acetylcholine)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905920"(positive regulation of CoA-transferase activity)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001988"(positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure)|go:"GO:0005216"(ion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006811"(ion transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007613"(memory)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007611"(learning or memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030673"(axolemma)|go:"GO:0032094"(response to food)|go:"GO:0030424"(axon)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0050893"(sensory processing)|go:"GO:0051117"(ATPase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|rgd:2348|reactome:R-RNO-629594|refseq:NP_036964.3|interpro:IPR036719|interpro:IPR036734	-	comment:mint|function:"Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to muscular and neuronal (alpha-7, alpha-8, and alpha-9) nicotinic acetylcholine receptors. Blocks the extracellular increase of dopamine evoked by nicotine only at the higher dose (4.2 uM)"	-	figure legend:"Fig. 3a (lane 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells)	-	2015/04/21	2015/09/22	rogid:H8HmrCO0Ummh3xuVj5FOUmoCcN08616	rogid:JMMrLrOpwsSACaDfzOCXTed3Y7M10116	rigid:VEuFz4Dh9oEG7yzPsIerWWYKROQ	false	125i radiolabel:?-?	-	-	1	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P60615	uniprotkb:Q05941	intact:EBI-7516391|uniprotkb:Q9PRI6|uniprotkb:Q9YI07|uniprotkb:P01378|uniprotkb:Q9YGD1|uniprotkb:Q9YI11|uniprotkb:Q9YI06|intact:MINT-5223718|uniprotkb:Q9YI09|uniprotkb:Q9YI10|uniprotkb:Q9YI13|uniprotkb:Q9YI12	intact:EBI-79422|uniprotkb:Q53YK2	psi-mi:3l21a_bunmu(display_long)|uniprotkb:Long neurotoxin 1(gene name synonym)|uniprotkb:Alpha-bungarotoxin, isoform A31(gene name synonym)|uniprotkb:Alpha-elapitoxin-Bm2a(gene name synonym)	psi-mi:acha7_rat(display_long)|uniprotkb:Chrna7(gene name)|psi-mi:Chrna7(display_short)|uniprotkb:Acra7(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Drisdel et al. (2000)	pubmed:10627589|imex:IM-24071	taxid:8616(bunmu)|taxid:8616(Bungarus multicinctus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10767094|imex:IM-24071-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P60615|interpro:IPR035076|interpro:IPR018354|interpro:IPR003571(Snake toxin)|go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|rcsb pdb:1ABT|rcsb pdb:1BXP|rcsb pdb:1HAA|rcsb pdb:1HAJ|rcsb pdb:1HC9|rcsb pdb:1HOY|rcsb pdb:1IDG|rcsb pdb:1IDH|rcsb pdb:1IDI|rcsb pdb:1IDL|rcsb pdb:1IK8|rcsb pdb:1IKC|rcsb pdb:1JBD|rcsb pdb:1KC4|rcsb pdb:1KFH|rcsb pdb:1KL8|rcsb pdb:1L4W|rcsb pdb:1LJZ|rcsb pdb:1LK1|rcsb pdb:1RGJ|rcsb pdb:2ABX|rcsb pdb:2BTX|rcsb pdb:6UWZ	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0060112"(generation of ovulation cycle rhythm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099065"(integral component of spine apparatus membrane)|go:"GO:0140059"(dendrite arborization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1905144"(response to acetylcholine)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905920"(positive regulation of CoA-transferase activity)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001988"(positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure)|go:"GO:0005216"(ion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006811"(ion transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007613"(memory)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007611"(learning or memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030673"(axolemma)|go:"GO:0032094"(response to food)|go:"GO:0030424"(axon)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0050893"(sensory processing)|go:"GO:0051117"(ATPase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|rgd:2348|reactome:R-RNO-629594|refseq:NP_036964.3|interpro:IPR036719|interpro:IPR036734	-	comment:mint|function:"Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to muscular and neuronal (alpha-7, alpha-8, and alpha-9) nicotinic acetylcholine receptors. Blocks the extracellular increase of dopamine evoked by nicotine only at the higher dose (4.2 uM)"	-	figure legend:"Fig. 3a (lane 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells)	-	2015/04/21	2015/09/22	rogid:H8HmrCO0Ummh3xuVj5FOUmoCcN08616	rogid:JMMrLrOpwsSACaDfzOCXTed3Y7M10116	rigid:VEuFz4Dh9oEG7yzPsIerWWYKROQ	false	125i radiolabel:?-?	-	-	1	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P60615	uniprotkb:Q05941	intact:EBI-7516391|uniprotkb:Q9PRI6|uniprotkb:Q9YI07|uniprotkb:P01378|uniprotkb:Q9YGD1|uniprotkb:Q9YI11|uniprotkb:Q9YI06|intact:MINT-5223718|uniprotkb:Q9YI09|uniprotkb:Q9YI10|uniprotkb:Q9YI13|uniprotkb:Q9YI12	intact:EBI-79422|uniprotkb:Q53YK2	psi-mi:3l21a_bunmu(display_long)|uniprotkb:Long neurotoxin 1(gene name synonym)|uniprotkb:Alpha-bungarotoxin, isoform A31(gene name synonym)|uniprotkb:Alpha-elapitoxin-Bm2a(gene name synonym)	psi-mi:acha7_rat(display_long)|uniprotkb:Chrna7(gene name)|psi-mi:Chrna7(display_short)|uniprotkb:Acra7(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Drisdel et al. (2000)	pubmed:10627589|imex:IM-24071	taxid:8616(bunmu)|taxid:8616(Bungarus multicinctus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10767102|imex:IM-24071-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P60615|interpro:IPR035076|interpro:IPR018354|interpro:IPR003571(Snake toxin)|go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|rcsb pdb:1ABT|rcsb pdb:1BXP|rcsb pdb:1HAA|rcsb pdb:1HAJ|rcsb pdb:1HC9|rcsb pdb:1HOY|rcsb pdb:1IDG|rcsb pdb:1IDH|rcsb pdb:1IDI|rcsb pdb:1IDL|rcsb pdb:1IK8|rcsb pdb:1IKC|rcsb pdb:1JBD|rcsb pdb:1KC4|rcsb pdb:1KFH|rcsb pdb:1KL8|rcsb pdb:1L4W|rcsb pdb:1LJZ|rcsb pdb:1LK1|rcsb pdb:1RGJ|rcsb pdb:2ABX|rcsb pdb:2BTX|rcsb pdb:6UWZ	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0060112"(generation of ovulation cycle rhythm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099065"(integral component of spine apparatus membrane)|go:"GO:0140059"(dendrite arborization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1905144"(response to acetylcholine)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905920"(positive regulation of CoA-transferase activity)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001988"(positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure)|go:"GO:0005216"(ion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006811"(ion transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007613"(memory)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007611"(learning or memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030673"(axolemma)|go:"GO:0032094"(response to food)|go:"GO:0030424"(axon)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0050893"(sensory processing)|go:"GO:0051117"(ATPase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|rgd:2348|reactome:R-RNO-629594|refseq:NP_036964.3|interpro:IPR036719|interpro:IPR036734	-	comment:mint|function:"Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to muscular and neuronal (alpha-7, alpha-8, and alpha-9) nicotinic acetylcholine receptors. Blocks the extracellular increase of dopamine evoked by nicotine only at the higher dose (4.2 uM)"	-	figure legend:"Fig. 3a (lane 4)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells)	-	2015/04/21	2015/09/22	rogid:H8HmrCO0Ummh3xuVj5FOUmoCcN08616	rogid:JMMrLrOpwsSACaDfzOCXTed3Y7M10116	rigid:VEuFz4Dh9oEG7yzPsIerWWYKROQ	false	125i radiolabel:?-?	-	-	1	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P60615	uniprotkb:Q05941	intact:EBI-7516391|uniprotkb:Q9PRI6|uniprotkb:Q9YI07|uniprotkb:P01378|uniprotkb:Q9YGD1|uniprotkb:Q9YI11|uniprotkb:Q9YI06|intact:MINT-5223718|uniprotkb:Q9YI09|uniprotkb:Q9YI10|uniprotkb:Q9YI13|uniprotkb:Q9YI12	intact:EBI-79422|uniprotkb:Q53YK2	psi-mi:3l21a_bunmu(display_long)|uniprotkb:Long neurotoxin 1(gene name synonym)|uniprotkb:Alpha-bungarotoxin, isoform A31(gene name synonym)|uniprotkb:Alpha-elapitoxin-Bm2a(gene name synonym)	psi-mi:acha7_rat(display_long)|uniprotkb:Chrna7(gene name)|psi-mi:Chrna7(display_short)|uniprotkb:Acra7(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Drisdel et al. (2000)	pubmed:10627589|imex:IM-24071	taxid:8616(bunmu)|taxid:8616(Bungarus multicinctus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10767212|imex:IM-24071-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P60615|interpro:IPR035076|interpro:IPR018354|interpro:IPR003571(Snake toxin)|go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|rcsb pdb:1ABT|rcsb pdb:1BXP|rcsb pdb:1HAA|rcsb pdb:1HAJ|rcsb pdb:1HC9|rcsb pdb:1HOY|rcsb pdb:1IDG|rcsb pdb:1IDH|rcsb pdb:1IDI|rcsb pdb:1IDL|rcsb pdb:1IK8|rcsb pdb:1IKC|rcsb pdb:1JBD|rcsb pdb:1KC4|rcsb pdb:1KFH|rcsb pdb:1KL8|rcsb pdb:1L4W|rcsb pdb:1LJZ|rcsb pdb:1LK1|rcsb pdb:1RGJ|rcsb pdb:2ABX|rcsb pdb:2BTX|rcsb pdb:6UWZ	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0060112"(generation of ovulation cycle rhythm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099065"(integral component of spine apparatus membrane)|go:"GO:0140059"(dendrite arborization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1905144"(response to acetylcholine)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905920"(positive regulation of CoA-transferase activity)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001988"(positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure)|go:"GO:0005216"(ion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006811"(ion transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007613"(memory)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007611"(learning or memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030673"(axolemma)|go:"GO:0032094"(response to food)|go:"GO:0030424"(axon)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0050893"(sensory processing)|go:"GO:0051117"(ATPase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|rgd:2348|reactome:R-RNO-629594|refseq:NP_036964.3|interpro:IPR036719|interpro:IPR036734	-	comment:mint|function:"Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to muscular and neuronal (alpha-7, alpha-8, and alpha-9) nicotinic acetylcholine receptors. Blocks the extracellular increase of dopamine evoked by nicotine only at the higher dose (4.2 uM)"	-	figure legend:"Fig. 3d (lane 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells)	-	2015/04/21	2015/09/22	rogid:H8HmrCO0Ummh3xuVj5FOUmoCcN08616	rogid:JMMrLrOpwsSACaDfzOCXTed3Y7M10116	rigid:VEuFz4Dh9oEG7yzPsIerWWYKROQ	false	125i radiolabel:?-?	-	-	1	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q05941	-	intact:EBI-79422|uniprotkb:Q53YK2	-	psi-mi:acha7_rat(display_long)|uniprotkb:Chrna7(gene name)|psi-mi:Chrna7(display_short)|uniprotkb:Acra7(gene name synonym)	-	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Drisdel et al. (2000)	pubmed:10627589|imex:IM-24071	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	-	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10767155|imex:IM-24071-7	-	-	psi-mi:"MI:0499"(unspecified role)	-	psi-mi:"MI:0497"(neutral component)	-	psi-mi:"MI:0326"(protein)	-	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0060112"(generation of ovulation cycle rhythm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099065"(integral component of spine apparatus membrane)|go:"GO:0140059"(dendrite arborization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1905144"(response to acetylcholine)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905920"(positive regulation of CoA-transferase activity)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001988"(positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure)|go:"GO:0005216"(ion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006811"(ion transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007613"(memory)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007611"(learning or memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030673"(axolemma)|go:"GO:0032094"(response to food)|go:"GO:0030424"(axon)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0050893"(sensory processing)|go:"GO:0051117"(ATPase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|rgd:2348|reactome:R-RNO-629594|refseq:NP_036964.3|interpro:IPR036719|interpro:IPR036734	-	-	-	-	figure legend:"Fig. 5 (lane 4)"|comment:Addition of alkylation agent NEM and/or reducing agent DTT results in only monomers of alpha7 subunits.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2015/04/21	2015/09/22	rogid:JMMrLrOpwsSACaDfzOCXTed3Y7M10116	-	-	false	-	-	1	-	psi-mi:"MI:0113"(western blot)	-
uniprotkb:Q05941	-	intact:EBI-79422|uniprotkb:Q53YK2	-	psi-mi:acha7_rat(display_long)|uniprotkb:Chrna7(gene name)|psi-mi:Chrna7(display_short)|uniprotkb:Acra7(gene name synonym)	-	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Drisdel et al. (2000)	pubmed:10627589|imex:IM-24071	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	-	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10767191|imex:IM-24071-11	-	-	psi-mi:"MI:0499"(unspecified role)	-	psi-mi:"MI:0497"(neutral component)	-	psi-mi:"MI:0326"(protein)	-	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0060112"(generation of ovulation cycle rhythm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099065"(integral component of spine apparatus membrane)|go:"GO:0140059"(dendrite arborization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1905144"(response to acetylcholine)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905920"(positive regulation of CoA-transferase activity)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001988"(positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure)|go:"GO:0005216"(ion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006811"(ion transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007613"(memory)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007611"(learning or memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030673"(axolemma)|go:"GO:0032094"(response to food)|go:"GO:0030424"(axon)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0050893"(sensory processing)|go:"GO:0051117"(ATPase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|rgd:2348|reactome:R-RNO-629594|refseq:NP_036964.3|interpro:IPR036719|interpro:IPR036734	-	-	-	-	figure legend:"Fig. 5 (lane 8)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells)	-	2015/04/21	2015/09/22	rogid:JMMrLrOpwsSACaDfzOCXTed3Y7M10116	-	-	false	-	-	1	-	psi-mi:"MI:0113"(western blot)	-
uniprotkb:Q05941	-	intact:EBI-79422|uniprotkb:Q53YK2	-	psi-mi:acha7_rat(display_long)|uniprotkb:Chrna7(gene name)|psi-mi:Chrna7(display_short)|uniprotkb:Acra7(gene name synonym)	-	psi-mi:"MI:0808"(comigration in sds page)	Drisdel et al. (2000)	pubmed:10627589|imex:IM-24071	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	-	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10816717|imex:IM-24071-13	-	-	psi-mi:"MI:0499"(unspecified role)	-	psi-mi:"MI:0497"(neutral component)	-	psi-mi:"MI:0326"(protein)	-	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0060112"(generation of ovulation cycle rhythm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099065"(integral component of spine apparatus membrane)|go:"GO:0140059"(dendrite arborization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1905144"(response to acetylcholine)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905920"(positive regulation of CoA-transferase activity)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001988"(positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure)|go:"GO:0005216"(ion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006811"(ion transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007613"(memory)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007611"(learning or memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030673"(axolemma)|go:"GO:0032094"(response to food)|go:"GO:0030424"(axon)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0050893"(sensory processing)|go:"GO:0051117"(ATPase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|rgd:2348|reactome:R-RNO-629594|refseq:NP_036964.3|interpro:IPR036719|interpro:IPR036734	-	-	-	-	figure legend:Fig. 4b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells)	-	2015/04/21	2015/09/22	rogid:JMMrLrOpwsSACaDfzOCXTed3Y7M10116	-	-	false	35s radiolabel:?-?	-	1	-	psi-mi:"MI:0113"(western blot)	-