#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P48548 uniprotkb:P48548 intact:EBI-9973587|ensembl:ENSRNOP00000048134 intact:EBI-9973587|ensembl:ENSRNOP00000048134 psi-mi:kcnj5_rat(display_long)|uniprotkb:Kcnj5(gene name)|psi-mi:Kcnj5(display_short)|uniprotkb:Girk4(gene name synonym)|uniprotkb:Cardiac inward rectifier(gene name synonym)|uniprotkb:Heart KATP channel(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir3.4"(gene name synonym)|uniprotkb:KATP-1(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 5(gene name synonym) psi-mi:kcnj5_rat(display_long)|uniprotkb:Kcnj5(gene name)|psi-mi:Kcnj5(display_short)|uniprotkb:Girk4(gene name synonym)|uniprotkb:Cardiac inward rectifier(gene name synonym)|uniprotkb:Heart KATP channel(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir3.4"(gene name synonym)|uniprotkb:KATP-1(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Corey et al. (1998) pubmed:9765280|imex:IM-23327 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9973585|imex:IM-23327-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058993.1|rgd:61971|ensembl:ENSRNOG00000033796(gene)|ensembl:ENSRNOT00000041038(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015467"(G-protein activated inward rectifier potassium channel activity)|go:"GO:0030315"(T-tubule)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003277(Potassium channel, inwardly rectifying, Kir3.4)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-997272 refseq:NP_058993.1|rgd:61971|ensembl:ENSRNOG00000033796(gene)|ensembl:ENSRNOT00000041038(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015467"(G-protein activated inward rectifier potassium channel activity)|go:"GO:0030315"(T-tubule)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003277(Potassium channel, inwardly rectifying, Kir3.4)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-997272 - - - figure legend:Fig. 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/11/06 2014/11/21 rogid:aDiu8r+WUoDRGaUjmqk21T/M2/810116 rogid:aDiu8r+WUoDRGaUjmqk21T/M2/810116 intact-crc:D39D4FEF6CCB7D06|rigid:OT9jikcqGQRESp148mS/3HBEgI0 false au1 tag:c-c au1 tag:c-c 4 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:E1BNE9 uniprotkb:F1MYR9 intact:EBI-9973959|ensembl:ENSBTAP00000008100 intact:EBI-9973944|ensembl:ENSBTAP00000073898 psi-mi:kcnj3_bovin(display_long)|uniprotkb:GIRK1(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir3.1"(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 3(gene name synonym)|uniprotkb:KCNJ3(gene name)|psi-mi:KCNJ3(display_short) psi-mi:kcnj5_bovin(display_long)|uniprotkb:Cardiac inward rectifier(gene name synonym)|uniprotkb:GIRK4(gene name synonym)|uniprotkb:Heart KATP channel(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir3.4"(gene name synonym)|uniprotkb:KATP-1(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 5(gene name synonym)|uniprotkb:KCNJ5(gene name)|psi-mi:KCNJ5(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Corey et al. (1998) pubmed:9765280|imex:IM-23327 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9973942|imex:IM-23327-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001179553.1|ensembl:ENSBTAG00000006159(gene)|ensembl:ENSBTAT00000008100(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015467"(G-protein activated inward rectifier potassium channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003274(Potassium channel, inwardly rectifying, Kir3.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647 refseq:XP_002699270.1|refseq:XP_005197363.1|refseq:XP_005197364.1|refseq:XP_005226885.1|refseq:XP_010819266.1|refseq:XP_010824575.1|ensembl:ENSBTAG00000006902(gene)|ensembl:ENSBTAT00000079814(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015467"(G-protein activated inward rectifier potassium channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003277(Potassium channel, inwardly rectifying, Kir3.4)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647 - - - figure legend:Fig. 2, 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-heart)|taxid:9913(Bos taurus heast) - 2014/11/06 2015/02/12 rogid:oMVbysiYKWLY5pCD1Jv3cZyyntE9913 rogid:Zb7KGQqlMET8100i2g/F5ggnFFE9913 intact-crc:BCD4E723E8A24E0A|rigid:/LpfApKxzVJw8p7soCJo5Y4u1GU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:F1MYR9 uniprotkb:F1MYR9 intact:EBI-9973944|ensembl:ENSBTAP00000073898 intact:EBI-9973944|ensembl:ENSBTAP00000073898 psi-mi:kcnj5_bovin(display_long)|uniprotkb:Cardiac inward rectifier(gene name synonym)|uniprotkb:GIRK4(gene name synonym)|uniprotkb:Heart KATP channel(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir3.4"(gene name synonym)|uniprotkb:KATP-1(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 5(gene name synonym)|uniprotkb:KCNJ5(gene name)|psi-mi:KCNJ5(display_short) psi-mi:kcnj5_bovin(display_long)|uniprotkb:Cardiac inward rectifier(gene name synonym)|uniprotkb:GIRK4(gene name synonym)|uniprotkb:Heart KATP channel(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir3.4"(gene name synonym)|uniprotkb:KATP-1(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 5(gene name synonym)|uniprotkb:KCNJ5(gene name)|psi-mi:KCNJ5(display_short) psi-mi:"MI:0071"(molecular sieving) Corey et al. (1998) pubmed:9765280|imex:IM-23327 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9982519|imex:IM-23327-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_002699270.1|refseq:XP_005197363.1|refseq:XP_005197364.1|refseq:XP_005226885.1|refseq:XP_010819266.1|refseq:XP_010824575.1|ensembl:ENSBTAG00000006902(gene)|ensembl:ENSBTAT00000079814(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015467"(G-protein activated inward rectifier potassium channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003277(Potassium channel, inwardly rectifying, Kir3.4)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647 refseq:XP_002699270.1|refseq:XP_005197363.1|refseq:XP_005197364.1|refseq:XP_005226885.1|refseq:XP_010819266.1|refseq:XP_010824575.1|ensembl:ENSBTAG00000006902(gene)|ensembl:ENSBTAT00000079814(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015467"(G-protein activated inward rectifier potassium channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003277(Potassium channel, inwardly rectifying, Kir3.4)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647 - - - figure legend:Fig.7|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-heart)|taxid:9913(Bos taurus heast) - 2014/11/06 2015/02/12 rogid:Zb7KGQqlMET8100i2g/F5ggnFFE9913 rogid:Zb7KGQqlMET8100i2g/F5ggnFFE9913 intact-crc:751F771AE356BE0E|rigid:em0ltpt7rAOvGnQhl/QCSUTytOw false - - 4 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:F1MYR9 uniprotkb:E1BNE9 intact:EBI-9973944|ensembl:ENSBTAP00000073898 intact:EBI-9973959|ensembl:ENSBTAP00000008100 psi-mi:kcnj5_bovin(display_long)|uniprotkb:Cardiac inward rectifier(gene name synonym)|uniprotkb:GIRK4(gene name synonym)|uniprotkb:Heart KATP channel(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir3.4"(gene name synonym)|uniprotkb:KATP-1(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 5(gene name synonym)|uniprotkb:KCNJ5(gene name)|psi-mi:KCNJ5(display_short) psi-mi:kcnj3_bovin(display_long)|uniprotkb:GIRK1(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir3.1"(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 3(gene name synonym)|uniprotkb:KCNJ3(gene name)|psi-mi:KCNJ3(display_short) psi-mi:"MI:0071"(molecular sieving) Corey et al. (1998) pubmed:9765280|imex:IM-23327 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9982502|imex:IM-23327-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_002699270.1|refseq:XP_005197363.1|refseq:XP_005197364.1|refseq:XP_005226885.1|refseq:XP_010819266.1|refseq:XP_010824575.1|ensembl:ENSBTAG00000006902(gene)|ensembl:ENSBTAT00000079814(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015467"(G-protein activated inward rectifier potassium channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003277(Potassium channel, inwardly rectifying, Kir3.4)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647 refseq:NP_001179553.1|ensembl:ENSBTAG00000006159(gene)|ensembl:ENSBTAT00000008100(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015467"(G-protein activated inward rectifier potassium channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003274(Potassium channel, inwardly rectifying, Kir3.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647 - - - figure legend:Fig. 7|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-heart)|taxid:9913(Bos taurus heast) - 2014/11/06 2015/02/12 rogid:Zb7KGQqlMET8100i2g/F5ggnFFE9913 rogid:oMVbysiYKWLY5pCD1Jv3cZyyntE9913 intact-crc:3DBF970048557DA8|rigid:/LpfApKxzVJw8p7soCJo5Y4u1GU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)