#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:29699"	uniprotkb:Q920L9	intact:EBI-9258360	intact:EBI-9209498	psi-mi:tunicamycin(display_short)|psi-mi:"CHEBI:29699"(display_long)|intact:Tunicamycin(synonym)	psi-mi:q920l9_mesau(display_long)|uniprotkb:EMEP(gene name synonym)|uniprotkb:Canx(gene name synonym)|uniprotkb:CNX(gene name)|psi-mi:CNX(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choukhi et al. (1998)	pubmed:9557669|imex:IM-26020	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9258357|imex:IM-26020-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001268806.1|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR018124|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0005509"(calcium ion binding)	-	-	-	figure legend:Fig. 1, 3, 4 and 6|comment:"Tunicamycin and castanospermine (CST) inhibit e1-calnexin interaction. Tunicamycin blocks core glycosylation of nascent glycoprotein precursors. Results suggest that in the absence of their N-linked oligosaccharides, HCV glycoproteins are unable to fold properly."|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk)|taxid:10036(Mesocricetus auratus baby kidney cell line BHK)	-	2014/02/17	2019/01/30	-	rogid:MtFcn1ZxjvJW/tj7szVDD38gh9g10036	intact-crc:9A7B6E956F734C22	false	-	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q920L9	uniprotkb:P27958-PRO_0000037569	intact:EBI-9209498	intact:EBI-6904259	psi-mi:q920l9_mesau(display_long)|uniprotkb:EMEP(gene name synonym)|uniprotkb:Canx(gene name synonym)|uniprotkb:CNX(gene name)|psi-mi:CNX(display_short)	psi-mi:p27958-pro_0000037569(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choukhi et al. (1998)	pubmed:9557669|imex:IM-26020	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9258357|imex:IM-26020-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268806.1|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR018124|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0005509"(calcium ion binding)	intact:EBI-706378(chain-parent)	-	-	chain-seq-start:192|chain-seq-end:383	figure legend:Fig. 1, 3, 4 and 6|comment:"Tunicamycin and castanospermine (CST) inhibit e1-calnexin interaction. Tunicamycin blocks core glycosylation of nascent glycoprotein precursors. Results suggest that in the absence of their N-linked oligosaccharides, HCV glycoproteins are unable to fold properly."|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk)|taxid:10036(Mesocricetus auratus baby kidney cell line BHK)	-	2014/02/17	2019/01/30	rogid:MtFcn1ZxjvJW/tj7szVDD38gh9g10036	rogid:lHQtQrLesdnnI8S6ssrTTL3OqlM63746	intact-crc:9A7B6E956F734C22	false	35s radiolabel:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
chebi:"CHEBI:27860"	uniprotkb:Q920L9	intact:EBI-9258340|chebi:"CHEBI:224519"|chebi:"CHEBI:41729"|chebi:"CHEBI:23050"|chebi:"CHEBI:3459"	intact:EBI-9209498	psi-mi:castanospermine(display_short)|psi-mi:"CHEBI:27860"(display_long)|intact:"(1S,6S,7R,8R,8aR)-1,6,7,8-tetrahydroxyindolizidine"(synonym)|intact:"(1S-(1alpha,6beta,7alpha,8beta,8alphabeta))-octahydro-1,6,7,8-indolizinetetrol"(synonym)|intact:1,6,7,8-tetrahydroxyoctahydroindolizine(synonym)|intact:Castanospermine(synonym)|intact:CASTANOSPERMINE(synonym)|intact:castinospermine(synonym)|intact:"(1S,6S,7R,8R,8aR)-octahydroindolizine-1,6,7,8-tetrol"(iupac name)	psi-mi:q920l9_mesau(display_long)|uniprotkb:EMEP(gene name synonym)|uniprotkb:Canx(gene name synonym)|uniprotkb:CNX(gene name)|psi-mi:CNX(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choukhi et al. (1998)	pubmed:9557669|imex:IM-26020	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9209466|imex:IM-26020-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001268806.1|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR018124|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0005509"(calcium ion binding)	-	inchi key:JDVVGAQPNNXQDW-TVNFTVLESA-N	-	figure legend:Fig. 1, 3, 4 and 6|comment:"Ttunicamycin and castanospermine (CST) inhibit e1-calnexin interaction.  CST is an α-glucosidase inhibitor that prevents glucose trimming. As such, it inhibits glycoprotein binding to calnexin."|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk)|taxid:10036(Mesocricetus auratus baby kidney cell line BHK)	-	2014/02/17	2014/10/16	-	rogid:MtFcn1ZxjvJW/tj7szVDD38gh9g10036	intact-crc:FA617ADBBC4C1E58	false	-	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q920L9	uniprotkb:P27958-PRO_0000037569	intact:EBI-9209498	intact:EBI-6904259	psi-mi:q920l9_mesau(display_long)|uniprotkb:EMEP(gene name synonym)|uniprotkb:Canx(gene name synonym)|uniprotkb:CNX(gene name)|psi-mi:CNX(display_short)	psi-mi:p27958-pro_0000037569(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choukhi et al. (1998)	pubmed:9557669|imex:IM-26020	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9209466|imex:IM-26020-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268806.1|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR018124|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0005509"(calcium ion binding)	intact:EBI-706378(chain-parent)	-	-	chain-seq-start:192|chain-seq-end:383	figure legend:Fig. 1, 3, 4 and 6|comment:"Ttunicamycin and castanospermine (CST) inhibit e1-calnexin interaction.  CST is an α-glucosidase inhibitor that prevents glucose trimming. As such, it inhibits glycoprotein binding to calnexin."|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk)|taxid:10036(Mesocricetus auratus baby kidney cell line BHK)	-	2014/02/17	2014/10/16	rogid:MtFcn1ZxjvJW/tj7szVDD38gh9g10036	rogid:lHQtQrLesdnnI8S6ssrTTL3OqlM63746	intact-crc:FA617ADBBC4C1E58	false	35s radiolabel:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q920L9	uniprotkb:P27958-PRO_0000037570	intact:EBI-9209498	intact:EBI-6904269	psi-mi:q920l9_mesau(display_long)|uniprotkb:EMEP(gene name synonym)|uniprotkb:Canx(gene name synonym)|uniprotkb:CNX(gene name)|psi-mi:CNX(display_short)	psi-mi:p27958-pro_0000037570(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choukhi et al. (1998)	pubmed:9557669|imex:IM-26020	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9209522|imex:IM-26020-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268806.1|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR018124|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0005509"(calcium ion binding)	intact:EBI-706378(chain-parent)	-	-	chain-seq-start:384|chain-seq-end:746	figure legend:Fig. 1, 3, 4 and 6|comment:In fig. 6 data shows that tunicamycin inhibit e2-calnexin interaction|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk)|taxid:10036(Mesocricetus auratus baby kidney cell line BHK)	-	2014/02/17	2017/09/02	rogid:MtFcn1ZxjvJW/tj7szVDD38gh9g10036	rogid:XFfKziasvR5/eMo+Xm/kI2cwpPc63746	intact-crc:0AE61FD4F2D1AE1B|rigid:v7ONrbAApqN4HRp0fO2ReVf3BvM	false	35s radiolabel:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P27958-PRO_0000037570	uniprotkb:P07823	intact:EBI-6904269	intact:EBI-371776	psi-mi:p27958-pro_0000037570(display_long)	psi-mi:bip_mesau(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:GRP78(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choukhi et al. (1998)	pubmed:9557669|imex:IM-26020	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9209516|imex:IM-26020-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-706378(chain-parent)	go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|dip:DIP-29677N	-	chain-seq-start:384|chain-seq-end:746	-	figure legend:Fig. 1, 3, 4 and 6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk)|taxid:10036(Mesocricetus auratus baby kidney cell line BHK)	-	2014/02/17	2017/09/02	rogid:XFfKziasvR5/eMo+Xm/kI2cwpPc63746	rogid:JdZKgGCixM5M26SXAYdJMRbHSEE10036	intact-crc:9FC894C2A471D981|rigid:dncbtlncnrUk5nZ9lv2T5eY+LO4	false	35s radiolabel:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P07823	uniprotkb:P27958-PRO_0000037569	intact:EBI-371776	intact:EBI-6904259	psi-mi:bip_mesau(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:GRP78(gene name synonym)	psi-mi:p27958-pro_0000037569(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choukhi et al. (1998)	pubmed:9557669|imex:IM-26020	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9209512|imex:IM-26020-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|dip:DIP-29677N	intact:EBI-706378(chain-parent)	-	-	chain-seq-start:192|chain-seq-end:383	figure legend:Fig. 1, 3, 4 and 6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk)|taxid:10036(Mesocricetus auratus baby kidney cell line BHK)	-	2014/02/17	2017/09/02	rogid:JdZKgGCixM5M26SXAYdJMRbHSEE10036	rogid:lHQtQrLesdnnI8S6ssrTTL3OqlM63746	intact-crc:2F7D0C8655325BD9|rigid:3JBazmlrHp77K/oNJap1RxEE7Kc	false	35s radiolabel:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P07823	uniprotkb:P27958-PRO_0000037569	intact:EBI-371776	intact:EBI-6904259	psi-mi:bip_mesau(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:GRP78(gene name synonym)	psi-mi:p27958-pro_0000037569(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choukhi et al. (1998)	pubmed:9557669|imex:IM-26020	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9209551|imex:IM-26020-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|dip:DIP-29677N	intact:EBI-706378(chain-parent)	-	-	chain-seq-start:192|chain-seq-end:383	figure legend:Fig. 4|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk)|taxid:10036(Mesocricetus auratus baby kidney cell line BHK)	-	2014/02/17	2017/09/02	rogid:JdZKgGCixM5M26SXAYdJMRbHSEE10036	rogid:lHQtQrLesdnnI8S6ssrTTL3OqlM63746	intact-crc:06131692DF4F29C4|rigid:yaGF2DEdzTeCHathUT1t4a4dH5E	false	35s radiolabel:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P07823	uniprotkb:P27958-PRO_0000037570	intact:EBI-371776	intact:EBI-6904269	psi-mi:bip_mesau(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:GRP78(gene name synonym)	psi-mi:p27958-pro_0000037570(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choukhi et al. (1998)	pubmed:9557669|imex:IM-26020	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9209551|imex:IM-26020-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|dip:DIP-29677N	intact:EBI-706378(chain-parent)	-	-	chain-seq-start:384|chain-seq-end:746	figure legend:Fig. 4|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk)|taxid:10036(Mesocricetus auratus baby kidney cell line BHK)	-	2014/02/17	2017/09/02	rogid:JdZKgGCixM5M26SXAYdJMRbHSEE10036	rogid:XFfKziasvR5/eMo+Xm/kI2cwpPc63746	intact-crc:06131692DF4F29C4|rigid:yaGF2DEdzTeCHathUT1t4a4dH5E	false	35s radiolabel:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q920L9	uniprotkb:P27958-PRO_0000037569	intact:EBI-9209498	intact:EBI-6904259	psi-mi:q920l9_mesau(display_long)|uniprotkb:EMEP(gene name synonym)|uniprotkb:Canx(gene name synonym)|uniprotkb:CNX(gene name)|psi-mi:CNX(display_short)	psi-mi:p27958-pro_0000037569(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choukhi et al. (1998)	pubmed:9557669|imex:IM-26020	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9209542|imex:IM-26020-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268806.1|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR018124|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0005509"(calcium ion binding)	intact:EBI-706378(chain-parent)	-	-	chain-seq-start:192|chain-seq-end:383	figure legend:Fig. 4|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk)|taxid:10036(Mesocricetus auratus baby kidney cell line BHK)	-	2014/02/17	2017/09/02	rogid:MtFcn1ZxjvJW/tj7szVDD38gh9g10036	rogid:lHQtQrLesdnnI8S6ssrTTL3OqlM63746	intact-crc:AEE98177E345307A|rigid:JUSVJqzkV22nUuRU3kdwA7sTA1w	false	35s radiolabel:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q920L9	uniprotkb:P27958-PRO_0000037570	intact:EBI-9209498	intact:EBI-6904269	psi-mi:q920l9_mesau(display_long)|uniprotkb:EMEP(gene name synonym)|uniprotkb:Canx(gene name synonym)|uniprotkb:CNX(gene name)|psi-mi:CNX(display_short)	psi-mi:p27958-pro_0000037570(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choukhi et al. (1998)	pubmed:9557669|imex:IM-26020	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9209542|imex:IM-26020-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268806.1|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR018124|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0005509"(calcium ion binding)	intact:EBI-706378(chain-parent)	-	-	chain-seq-start:384|chain-seq-end:746	figure legend:Fig. 4|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk)|taxid:10036(Mesocricetus auratus baby kidney cell line BHK)	-	2014/02/17	2017/09/02	rogid:MtFcn1ZxjvJW/tj7szVDD38gh9g10036	rogid:XFfKziasvR5/eMo+Xm/kI2cwpPc63746	intact-crc:AEE98177E345307A|rigid:JUSVJqzkV22nUuRU3kdwA7sTA1w	false	35s radiolabel:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P27958-PRO_0000037569	uniprotkb:P27958-PRO_0000037570	intact:EBI-6904259	intact:EBI-6904269	psi-mi:p27958-pro_0000037569(display_long)	psi-mi:p27958-pro_0000037570(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choukhi et al. (1998)	pubmed:9557669|imex:IM-26020	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9258332|imex:IM-26020-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-706378(chain-parent)	intact:EBI-706378(chain-parent)	-	chain-seq-start:192|chain-seq-end:383	chain-seq-start:384|chain-seq-end:746	figure legend:Fig. 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk)|taxid:10036(Mesocricetus auratus baby kidney cell line BHK)	-	2014/02/17	2017/09/02	rogid:lHQtQrLesdnnI8S6ssrTTL3OqlM63746	rogid:XFfKziasvR5/eMo+Xm/kI2cwpPc63746	intact-crc:7C301A0FF285ABA0|rigid:mOra/Qb+QsNl+L8kGNx95j2ZUts	false	35s radiolabel:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P07823	uniprotkb:P27958-PRO_0000037569	intact:EBI-371776	intact:EBI-6904259	psi-mi:bip_mesau(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:GRP78(gene name synonym)	psi-mi:p27958-pro_0000037569(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choukhi et al. (1998)	pubmed:9557669|imex:IM-26020	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9209581|imex:IM-26020-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|dip:DIP-29677N	intact:EBI-706378(chain-parent)	-	-	chain-seq-start:192|chain-seq-end:383	figure legend:Fig. 2|comment:ATP inhibits E1-BIP interaction|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk)|taxid:10036(Mesocricetus auratus baby kidney cell line BHK)	-	2014/02/17	2014/10/16	rogid:JdZKgGCixM5M26SXAYdJMRbHSEE10036	rogid:lHQtQrLesdnnI8S6ssrTTL3OqlM63746	intact-crc:632FFA0533B5F822|rigid:3JBazmlrHp77K/oNJap1RxEE7Kc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P27958-PRO_0000037570	uniprotkb:P07823	intact:EBI-6904269	intact:EBI-371776	psi-mi:p27958-pro_0000037570(display_long)	psi-mi:bip_mesau(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:GRP78(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choukhi et al. (1998)	pubmed:9557669|imex:IM-26020	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9209577|imex:IM-26020-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-706378(chain-parent)	go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|dip:DIP-29677N	-	chain-seq-start:384|chain-seq-end:746	-	figure legend:Fig. 2|comment:ATP inhibits E2-BIP interaction|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau-bhk)|taxid:10036(Mesocricetus auratus baby kidney cell line BHK)	-	2014/02/17	2014/10/16	rogid:XFfKziasvR5/eMo+Xm/kI2cwpPc63746	rogid:JdZKgGCixM5M26SXAYdJMRbHSEE10036	intact-crc:B171C893DFC1D137|rigid:dncbtlncnrUk5nZ9lv2T5eY+LO4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)