#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P13726	uniprotkb:P08709	intact:EBI-1040727|uniprotkb:Q6FHG2|uniprotkb:Q86WH4|uniprotkb:D3DT47|ensembl:ENSP00000334145	intact:EBI-355972|ensembl:ENSP00000364731|uniprotkb:Q14339|uniprotkb:Q5JVF2|uniprotkb:B0YJC8|uniprotkb:Q5JVF1|uniprotkb:Q9UD52|uniprotkb:Q9UD53|uniprotkb:Q9UD54	psi-mi:tf_human(display_long)|uniprotkb:F3(gene name)|psi-mi:F3(display_short)|uniprotkb:Coagulation factor III(gene name synonym)|uniprotkb:Thromboplastin(gene name synonym)	psi-mi:fa7_human(display_long)|uniprotkb:F7(gene name)|psi-mi:F7(display_short)|uniprotkb:Serum prothrombin conversion accelerator(gene name synonym)|uniprotkb:Proconvertin(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Leonard et al. (1998)	imex:IM-22272|pubmed:9414278	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9211753|imex:IM-22272-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001984.1|refseq:NP_001171567.1|ensembl:ENSG00000117525(gene)|ensembl:ENST00000334047(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002541"(activation of plasma proteins involved in acute inflammatory response)|go:"GO:0002543"(activation of blood coagulation via clotting cascade)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010641"(positive regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:1905286"(serine-type peptidase complex)|interpro:IPR001187(Tissue factor)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR030472|interpro:IPR036116|rcsb pdb:1AHW|rcsb pdb:1BOY|rcsb pdb:1DAN|rcsb pdb:1FAK|rcsb pdb:1J9C|rcsb pdb:1JPS|rcsb pdb:1NL8|rcsb pdb:1O5D|rcsb pdb:1UJ3|rcsb pdb:1W0Y|rcsb pdb:1W2K|rcsb pdb:1WQV|rcsb pdb:1WSS|rcsb pdb:1WTG|rcsb pdb:1WUN|rcsb pdb:1WV7|rcsb pdb:1Z6J|rcsb pdb:2A2Q|rcsb pdb:2AEI|rcsb pdb:2AER|rcsb pdb:2B7D|rcsb pdb:2B8O|rcsb pdb:2C4F|rcsb pdb:2CEF|rcsb pdb:2CEH|rcsb pdb:2CEZ|rcsb pdb:2CFJ|rcsb pdb:2EC9|rcsb pdb:2F9B|rcsb pdb:2FIR|rcsb pdb:2FLB|rcsb pdb:2FLR|rcsb pdb:2HFT|rcsb pdb:2PUQ|rcsb pdb:2ZP0|rcsb pdb:2ZWL|rcsb pdb:2ZZU|rcsb pdb:3ELA|rcsb pdb:3TH2|rcsb pdb:3TH3|rcsb pdb:3TH4|rcsb pdb:4IBL|rcsb pdb:4M7L|rcsb pdb:4YLQ|rcsb pdb:4Z6A|rcsb pdb:4ZMA|rcsb pdb:5W06|rcsb pdb:6R2W|reactome:R-HSA-140834|reactome:R-HSA-9031628|rcsb pdb:1TFH|dip:DIP-6136N	ensembl:ENSG00000057593(gene)|ensembl:ENST00000375581(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002690"(positive regulation of leukocyte chemotaxis)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007596"(blood coagulation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0010037"(response to carbon dioxide)|go:"GO:0010641"(positive regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016485"(protein processing)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032571"(response to vitamin K)|go:"GO:0033595"(response to genistein)|go:"GO:0043627"(response to estrogen)|rcsb pdb:1F7M|rcsb pdb:1FAK|rcsb pdb:1FF7|go:"GO:0050927"(positive regulation of positive chemotaxis)|rcsb pdb:1FFM|rcsb pdb:1J9C|rcsb pdb:1JBU|go:"GO:0051897"(positive regulation of protein kinase B signaling)|rcsb pdb:1KLI|go:"GO:0060416"(response to growth hormone)|go:"GO:0061476"(response to anticoagulant)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070723"(response to cholesterol)|go:"GO:0097068"(response to thyroxine)|go:"GO:1904400"(response to Thyroid stimulating hormone)|go:"GO:1904612"(response to 2,3,7,8-tetrachlorodibenzodioxine)|go:"GO:1905217"(response to astaxanthin)|go:"GO:1905225"(response to thyrotropin-releasing hormone)|go:"GO:1905286"(serine-type peptidase complex)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR018097|interpro:IPR018114|interpro:IPR033116|interpro:IPR033190|interpro:IPR035972|interpro:IPR043504|rcsb pdb:1BF9|rcsb pdb:1CVW|rcsb pdb:1DAN|rcsb pdb:1DVA|rcsb pdb:1F7E|rcsb pdb:1KLJ|rcsb pdb:1NL8|rcsb pdb:1O5D|rcsb pdb:1QFK|rcsb pdb:1W0Y|rcsb pdb:1W2K|rcsb pdb:1W7X|rcsb pdb:1W8B|rcsb pdb:1WQV|rcsb pdb:1WSS|rcsb pdb:1WTG|rcsb pdb:1WUN|rcsb pdb:1WV7|rcsb pdb:1YGC|rcsb pdb:1Z6J|rcsb pdb:2A2Q|rcsb pdb:2AEI|rcsb pdb:2AER|rcsb pdb:2B7D|rcsb pdb:2B8O|rcsb pdb:2BZ6|rcsb pdb:2C4F|rcsb pdb:2EC9|rcsb pdb:2F9B|rcsb pdb:2FIR|rcsb pdb:2FLB|rcsb pdb:2FLR|rcsb pdb:2PUQ|refseq:NP_000122.1|refseq:NP_062562.1|rcsb pdb:2ZP0|rcsb pdb:2ZWL|rcsb pdb:2ZZU|rcsb pdb:3ELA|rcsb pdb:3TH2|rcsb pdb:3TH3|rcsb pdb:3TH4|rcsb pdb:4IBL|rcsb pdb:4ISH|rcsb pdb:4ISI|rcsb pdb:4JYU|rcsb pdb:4JYV|rcsb pdb:4JZD|rcsb pdb:4JZE|rcsb pdb:4JZF|rcsb pdb:4NA9|rcsb pdb:4NG9|rcsb pdb:4NGA|rcsb pdb:4X8S|rcsb pdb:4X8T|rcsb pdb:4X8U|rcsb pdb:4X8V|rcsb pdb:4YLQ|rcsb pdb:4YT6|rcsb pdb:4YT7|rcsb pdb:4Z6A|rcsb pdb:4ZMA|rcsb pdb:4ZXX|rcsb pdb:4ZXY|rcsb pdb:5I46|rcsb pdb:5L0S|rcsb pdb:5L2Y|rcsb pdb:5L2Z|rcsb pdb:5L30|rcsb pdb:5PA8|rcsb pdb:5PA9|rcsb pdb:5PAA|rcsb pdb:5PAB|rcsb pdb:5PAC|rcsb pdb:5PAE|rcsb pdb:5PAF|rcsb pdb:5PAG|rcsb pdb:5PAI|rcsb pdb:5PAJ|rcsb pdb:5PAK|rcsb pdb:5PAM|rcsb pdb:5PAN|rcsb pdb:5PAO|rcsb pdb:5PAQ|rcsb pdb:5PAR|rcsb pdb:5PAS|rcsb pdb:5PAT|rcsb pdb:5PAU|rcsb pdb:5PAV|rcsb pdb:5PAW|rcsb pdb:5PAX|rcsb pdb:5PAY|rcsb pdb:5PB0|rcsb pdb:5PB1|rcsb pdb:5PB2|rcsb pdb:5PB3|rcsb pdb:5PB4|rcsb pdb:5PB5|rcsb pdb:5PB6|rcsb pdb:5TQE|rcsb pdb:5TQF|rcsb pdb:5TQG|rcsb pdb:5U6J|reactome:R-HSA-1368108|reactome:R-HSA-140834|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|dip:DIP-6135N	omim:227500(see-also)	-	-	figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/21	2014/10/16	rogid:/9cwpvhO2XibmA8HkQaSLRfA6689606	rogid:3AajTD0zonhwhwLyNtQ1rIKrgRI9606	intact-crc:9E6CBF4FF2A31217|rigid:WxavePK3rTAL+8L6SkzpYfuzjzg	false	-	mutation disrupting interaction:117-117|mutation decreasing interaction:139-139	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)