#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P02751 uniprotkb:P08519 intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839 intact:EBI-9232288|uniprotkb:Q5VTD7|uniprotkb:Q9UD88|ensembl:ENSP00000321334|ensembl:ENSP00000395608 psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym) psi-mi:apoa_human(display_long)|uniprotkb:LPA(gene name)|psi-mi:LPA(display_short) psi-mi:"MI:0018"(two hybrid) Köchl et al. (1997) pubmed:9269765|imex:IM-22297 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-9260029|imex:IM-22297-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223 ensembl:ENSG00000198670(gene)|ensembl:ENST00000316300(transcript)|ensembl:ENST00000447678(transcript)|go:"GO:0001968"(fibronectin binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0008015"(blood circulation)|go:"GO:0008201"(heparin binding)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034358"(plasma lipoprotein particle)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P08519|rcsb pdb:1I71|rcsb pdb:1JFN|rcsb pdb:1KIV|rcsb pdb:2FEB|rcsb pdb:3KIV|rcsb pdb:4BV5|rcsb pdb:4BV7|rcsb pdb:4BVC|rcsb pdb:4BVD|rcsb pdb:4BVV|rcsb pdb:4BVW|rcsb pdb:4KIV|rcsb pdb:6RX7|reactome:R-HSA-8964041 - - - figure legend:no figure|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/02/25 2019/10/18 rogid:4arZu49X8b+dthqaX4DIh59V8h09606 rogid:D9jx5U3Ke3Kq7u4mLcqtfBVysY09606 intact-crc:963A71D0D393F5AF|rigid:eD91E/L+4+aBjS4Xitw6Xaff2TA false - sufficient binding region:131..131-244..244(IPR000001) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02749 uniprotkb:P08519 intact:EBI-2114682|uniprotkb:Q9UCN7|uniprotkb:B2R9M3|ensembl:ENSP00000205948 intact:EBI-9232288|uniprotkb:Q5VTD7|uniprotkb:Q9UD88|ensembl:ENSP00000321334|ensembl:ENSP00000395608 psi-mi:apoh_human(display_long)|uniprotkb:APOH(gene name)|psi-mi:APOH(display_short)|uniprotkb:B2G1(gene name synonym)|uniprotkb:Beta-2-glycoprotein I(gene name synonym)|uniprotkb:Apolipoprotein H(gene name synonym)|uniprotkb:Activated protein C-binding protein(gene name synonym)|uniprotkb:APC inhibitor(gene name synonym)|uniprotkb:Anticardiolipin cofactor(gene name synonym) psi-mi:apoa_human(display_long)|uniprotkb:LPA(gene name)|psi-mi:LPA(display_short) psi-mi:"MI:0018"(two hybrid) Köchl et al. (1997) pubmed:9269765|imex:IM-22297 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-9247441|imex:IM-22297-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000033.2|dip:DIP-46878N|ensembl:ENSG00000091583(gene)|ensembl:ENST00000205948(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007597"(blood coagulation, intrinsic pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0034197"(triglyceride transport)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042802"(identical protein binding)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051917"(regulation of fibrinolysis)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0060230"(lipoprotein lipase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR015104(Beta-2-glycoprotein-1 fifth domain)|interpro:IPR035976|mint:P02749|rcsb pdb:1C1Z|rcsb pdb:1G4F|rcsb pdb:1G4G|rcsb pdb:1QUB|rcsb pdb:2KRI|rcsb pdb:3OP8|rcsb pdb:4JHS|rcsb pdb:6V06|rcsb pdb:6V08|rcsb pdb:6V09|reactome:R-HSA-114608 ensembl:ENSG00000198670(gene)|ensembl:ENST00000316300(transcript)|ensembl:ENST00000447678(transcript)|go:"GO:0001968"(fibronectin binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0008015"(blood circulation)|go:"GO:0008201"(heparin binding)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034358"(plasma lipoprotein particle)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P08519|rcsb pdb:1I71|rcsb pdb:1JFN|rcsb pdb:1KIV|rcsb pdb:2FEB|rcsb pdb:3KIV|rcsb pdb:4BV5|rcsb pdb:4BV7|rcsb pdb:4BVC|rcsb pdb:4BVD|rcsb pdb:4BVV|rcsb pdb:4BVW|rcsb pdb:4KIV|rcsb pdb:6RX7|reactome:R-HSA-8964041 - - - figure legend:Fig. 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/02/25 2014/10/16 rogid:IcohvxbMLnnzWe0jmOC0/KVvP1Y9606 rogid:D9jx5U3Ke3Kq7u4mLcqtfBVysY09606 intact-crc:C6CB9F3D3F9781E9|rigid:1VFwPCVVAK3ixpxRFetznYxF5Yw false necessary binding region:88-269 sufficient binding region:131..131-244..244(IPR000001) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P08519 uniprotkb:P02749 intact:EBI-9232288|uniprotkb:Q5VTD7|uniprotkb:Q9UD88|ensembl:ENSP00000321334|ensembl:ENSP00000395608 intact:EBI-2114682|uniprotkb:Q9UCN7|uniprotkb:B2R9M3|ensembl:ENSP00000205948 psi-mi:apoa_human(display_long)|uniprotkb:LPA(gene name)|psi-mi:LPA(display_short) psi-mi:apoh_human(display_long)|uniprotkb:APOH(gene name)|psi-mi:APOH(display_short)|uniprotkb:B2G1(gene name synonym)|uniprotkb:Beta-2-glycoprotein I(gene name synonym)|uniprotkb:Apolipoprotein H(gene name synonym)|uniprotkb:Activated protein C-binding protein(gene name synonym)|uniprotkb:APC inhibitor(gene name synonym)|uniprotkb:Anticardiolipin cofactor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Köchl et al. (1997) pubmed:9269765|imex:IM-22297 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-9276526|imex:IM-22297-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198670(gene)|ensembl:ENST00000316300(transcript)|ensembl:ENST00000447678(transcript)|go:"GO:0001968"(fibronectin binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0008015"(blood circulation)|go:"GO:0008201"(heparin binding)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034358"(plasma lipoprotein particle)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P08519|rcsb pdb:1I71|rcsb pdb:1JFN|rcsb pdb:1KIV|rcsb pdb:2FEB|rcsb pdb:3KIV|rcsb pdb:4BV5|rcsb pdb:4BV7|rcsb pdb:4BVC|rcsb pdb:4BVD|rcsb pdb:4BVV|rcsb pdb:4BVW|rcsb pdb:4KIV|rcsb pdb:6RX7|reactome:R-HSA-8964041 refseq:NP_000033.2|dip:DIP-46878N|ensembl:ENSG00000091583(gene)|ensembl:ENST00000205948(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007597"(blood coagulation, intrinsic pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0034197"(triglyceride transport)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042802"(identical protein binding)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051917"(regulation of fibrinolysis)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0060230"(lipoprotein lipase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR015104(Beta-2-glycoprotein-1 fifth domain)|interpro:IPR035976|mint:P02749|rcsb pdb:1C1Z|rcsb pdb:1G4F|rcsb pdb:1G4G|rcsb pdb:1QUB|rcsb pdb:2KRI|rcsb pdb:3OP8|rcsb pdb:4JHS|rcsb pdb:6V06|rcsb pdb:6V08|rcsb pdb:6V09|reactome:R-HSA-114608 - - - figure legend:Fig. 6|comment:"This interaction was also observed using the r-apo(a)K10 isoform. It is stated in this paper that this isoform has no repetitive KIV2 repeat. No information about its exact sequence is given by the authors."|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).") - 2014/02/25 2014/10/16 rogid:D9jx5U3Ke3Kq7u4mLcqtfBVysY09606 rogid:IcohvxbMLnnzWe0jmOC0/KVvP1Y9606 intact-crc:9A1D513C74B58EAD|rigid:1VFwPCVVAK3ixpxRFetznYxF5Yw false sufficient binding region:1-532,3041-4548 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P02749 uniprotkb:P08519 intact:EBI-2114682|uniprotkb:Q9UCN7|uniprotkb:B2R9M3|ensembl:ENSP00000205948 intact:EBI-9232288|uniprotkb:Q5VTD7|uniprotkb:Q9UD88|ensembl:ENSP00000321334|ensembl:ENSP00000395608 psi-mi:apoh_human(display_long)|uniprotkb:APOH(gene name)|psi-mi:APOH(display_short)|uniprotkb:B2G1(gene name synonym)|uniprotkb:Beta-2-glycoprotein I(gene name synonym)|uniprotkb:Apolipoprotein H(gene name synonym)|uniprotkb:Activated protein C-binding protein(gene name synonym)|uniprotkb:APC inhibitor(gene name synonym)|uniprotkb:Anticardiolipin cofactor(gene name synonym) psi-mi:apoa_human(display_long)|uniprotkb:LPA(gene name)|psi-mi:LPA(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Köchl et al. (1997) pubmed:9269765|imex:IM-22297 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-9247485|imex:IM-22297-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000033.2|dip:DIP-46878N|ensembl:ENSG00000091583(gene)|ensembl:ENST00000205948(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007597"(blood coagulation, intrinsic pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0034197"(triglyceride transport)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042802"(identical protein binding)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051917"(regulation of fibrinolysis)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0060230"(lipoprotein lipase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR015104(Beta-2-glycoprotein-1 fifth domain)|interpro:IPR035976|mint:P02749|rcsb pdb:1C1Z|rcsb pdb:1G4F|rcsb pdb:1G4G|rcsb pdb:1QUB|rcsb pdb:2KRI|rcsb pdb:3OP8|rcsb pdb:4JHS|rcsb pdb:6V06|rcsb pdb:6V08|rcsb pdb:6V09|reactome:R-HSA-114608 ensembl:ENSG00000198670(gene)|ensembl:ENST00000316300(transcript)|ensembl:ENST00000447678(transcript)|go:"GO:0001968"(fibronectin binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0008015"(blood circulation)|go:"GO:0008201"(heparin binding)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034358"(plasma lipoprotein particle)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P08519|rcsb pdb:1I71|rcsb pdb:1JFN|rcsb pdb:1KIV|rcsb pdb:2FEB|rcsb pdb:3KIV|rcsb pdb:4BV5|rcsb pdb:4BV7|rcsb pdb:4BVC|rcsb pdb:4BVD|rcsb pdb:4BVV|rcsb pdb:4BVW|rcsb pdb:4KIV|rcsb pdb:6RX7|reactome:R-HSA-8964041 - - - figure legend:Fig. 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-plasma)|taxid:9606(homo sapiens blood plasma) - 2014/02/25 2014/10/16 rogid:IcohvxbMLnnzWe0jmOC0/KVvP1Y9606 rogid:D9jx5U3Ke3Kq7u4mLcqtfBVysY09606 intact-crc:583F884E1D5AB302|rigid:1VFwPCVVAK3ixpxRFetznYxF5Yw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P02749 uniprotkb:P08519 intact:EBI-2114682|uniprotkb:Q9UCN7|uniprotkb:B2R9M3|ensembl:ENSP00000205948 intact:EBI-9232288|uniprotkb:Q5VTD7|uniprotkb:Q9UD88|ensembl:ENSP00000321334|ensembl:ENSP00000395608 psi-mi:apoh_human(display_long)|uniprotkb:APOH(gene name)|psi-mi:APOH(display_short)|uniprotkb:B2G1(gene name synonym)|uniprotkb:Beta-2-glycoprotein I(gene name synonym)|uniprotkb:Apolipoprotein H(gene name synonym)|uniprotkb:Activated protein C-binding protein(gene name synonym)|uniprotkb:APC inhibitor(gene name synonym)|uniprotkb:Anticardiolipin cofactor(gene name synonym) psi-mi:apoa_human(display_long)|uniprotkb:LPA(gene name)|psi-mi:LPA(display_short) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Köchl et al. (1997) pubmed:9269765|imex:IM-22297 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-9259477|imex:IM-22297-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000033.2|dip:DIP-46878N|ensembl:ENSG00000091583(gene)|ensembl:ENST00000205948(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007597"(blood coagulation, intrinsic pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0034197"(triglyceride transport)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042802"(identical protein binding)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051917"(regulation of fibrinolysis)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0060230"(lipoprotein lipase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR015104(Beta-2-glycoprotein-1 fifth domain)|interpro:IPR035976|mint:P02749|rcsb pdb:1C1Z|rcsb pdb:1G4F|rcsb pdb:1G4G|rcsb pdb:1QUB|rcsb pdb:2KRI|rcsb pdb:3OP8|rcsb pdb:4JHS|rcsb pdb:6V06|rcsb pdb:6V08|rcsb pdb:6V09|reactome:R-HSA-114608 ensembl:ENSG00000198670(gene)|ensembl:ENST00000316300(transcript)|ensembl:ENST00000447678(transcript)|go:"GO:0001968"(fibronectin binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0008015"(blood circulation)|go:"GO:0008201"(heparin binding)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034358"(plasma lipoprotein particle)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P08519|rcsb pdb:1I71|rcsb pdb:1JFN|rcsb pdb:1KIV|rcsb pdb:2FEB|rcsb pdb:3KIV|rcsb pdb:4BV5|rcsb pdb:4BV7|rcsb pdb:4BVC|rcsb pdb:4BVD|rcsb pdb:4BVV|rcsb pdb:4BVW|rcsb pdb:4KIV|rcsb pdb:6RX7|reactome:R-HSA-8964041 - - - figure legend:Fig. 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/02/25 2014/10/16 rogid:IcohvxbMLnnzWe0jmOC0/KVvP1Y9606 rogid:D9jx5U3Ke3Kq7u4mLcqtfBVysY09606 intact-crc:8DAE6C99B22F3F3E|rigid:1VFwPCVVAK3ixpxRFetznYxF5Yw false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)