#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P15382	uniprotkb:P97414	intact:EBI-7043557|ensembl:ENSP00000337255|ensembl:ENSP00000382225|ensembl:ENSP00000382226|ensembl:ENSP00000382228|ensembl:ENSP00000412498|ensembl:ENSP00000416258|ensembl:ENSP00000478215|ensembl:ENSP00000483895|uniprotkb:Q91Z94|intact:MINT-7297782|uniprotkb:Q8N709|uniprotkb:A5H1P2	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	psi-mi:kcne1_human(display_long)|uniprotkb:KCNE1(gene name)|psi-mi:KCNE1(display_short)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit beta Mink(gene name synonym)|uniprotkb:Minimal potassium channel(gene name synonym)|uniprotkb:Delayed rectifier potassium channel subunit IsK(gene name synonym)	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Barhanin et al. (1996)	imex:IM-23662|pubmed:8900282	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9869713|imex:IM-23662-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000180509(gene)|ensembl:ENST00000337385(transcript)|ensembl:ENST00000399284(transcript)|ensembl:ENST00000399286(transcript)|ensembl:ENST00000399289(transcript)|ensembl:ENST00000416357(transcript)|ensembl:ENST00000432085(transcript)|ensembl:ENST00000611936(transcript)|ensembl:ENST00000621601(transcript)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0031433"(telethonin binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000369(Potassium channel, voltage-dependent, beta subunit, KCNE)|interpro:IPR005424(Potassium channel, voltage-dependent, beta subunit, KCNE1)|mint:P15382|rcsb pdb:2K21|reactome:R-HSA-5576890|reactome:R-HSA-5576893|refseq:NP_001121141.1|refseq:NP_001121140.1|refseq:NP_000210.2|refseq:NP_001257334.1|refseq:NP_001257331.1|refseq:NP_001257333.1|refseq:NP_001257332.1|refseq:NP_001121142.1	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	-	comment:mint	-	figure legend:Fig. 5b|comment:"A stronger association of the glycosylated form of IsK to KvLQT1 is indicated by the enrichment of the IsK27K (glycosylated band) in the precipitate as compared to the 19K (unglycosylated) band."|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2014/10/22	2014/10/22	rogid:y68EBvBKDIRCu+MDWcaRVBtBoH09606	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	intact-crc:F526B55B9EBF1946|rigid:vy78tPurJVOEYybXjj62un4FiKs	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)