#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q06330 uniprotkb:P03203 intact:EBI-632552|uniprotkb:Q5XKH9|uniprotkb:Q6P1N3|ensembl:ENSP00000345206|ensembl:ENSP00000354528|ensembl:ENSP00000423644|uniprotkb:B4DY22 intact:EBI-9346250|uniprotkb:Q777E8 psi-mi:suh_human(display_long)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym)|uniprotkb:CBF-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-30(gene name synonym)|uniprotkb:RBPJ(gene name)|psi-mi:RBPJ(display_short)|uniprotkb:IGKJRB(gene name synonym)|uniprotkb:IGKJRB1(gene name synonym)|uniprotkb:RBPJK(gene name synonym)|uniprotkb:RBPSUH(gene name synonym) psi-mi:ebna4_ebvb9(display_long)|uniprotkb:EBNA4(gene name)|psi-mi:EBNA4(display_short)|uniprotkb:Epstein-Barr nuclear antigen 3B(gene name synonym)|uniprotkb:BERF2A-BERF2B(orf name) psi-mi:"MI:0096"(pull down) Robertson et al. (1996) imex:IM-22505|pubmed:8627785 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9346551|imex:IM-22505-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005340.2|refseq:NP_976028.1|refseq:NP_976029.1|refseq:NP_056958.3|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|go:"GO:0030183"(B cell differentiation)|rcsb pdb:2F8X|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:6PY8|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000168214(gene)|ensembl:ENST00000342295(transcript)|ensembl:ENST00000361572(transcript)|ensembl:ENST00000512671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|refseq:XP_005248218.1|refseq:XP_011512142.1|refseq:XP_016863661.1|refseq:XP_016863662.1|refseq:XP_016863663.1|refseq:XP_016863664.1|dip:DIP-33326N dip:DIP-573N|refseq:YP_401670.1|go:"GO:0016032"(viral process)|go:"GO:0042025"(host cell nucleus)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3) - - - figure legend:3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/03/18 2014/10/16 rogid:K86zd5i5jYfKx0hGupxu8rA8rDM9606 rogid:IpjWARPTNeJa3PZtsGfdgcU37Uo10377 intact-crc:3FDC33B17E34EFC1|rigid:AHRjugU6SHp9NDLSPDyCO1Wmh1A false glutathione s tranferase tag:?-? 14c radiolabel:?-?|sufficient binding region:1-109 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q06330 uniprotkb:P03203 intact:EBI-632552|uniprotkb:Q5XKH9|uniprotkb:Q6P1N3|ensembl:ENSP00000345206|ensembl:ENSP00000354528|ensembl:ENSP00000423644|uniprotkb:B4DY22 intact:EBI-9346250|uniprotkb:Q777E8 psi-mi:suh_human(display_long)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym)|uniprotkb:CBF-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-30(gene name synonym)|uniprotkb:RBPJ(gene name)|psi-mi:RBPJ(display_short)|uniprotkb:IGKJRB(gene name synonym)|uniprotkb:IGKJRB1(gene name synonym)|uniprotkb:RBPJK(gene name synonym)|uniprotkb:RBPSUH(gene name synonym) psi-mi:ebna4_ebvb9(display_long)|uniprotkb:EBNA4(gene name)|psi-mi:EBNA4(display_short)|uniprotkb:Epstein-Barr nuclear antigen 3B(gene name synonym)|uniprotkb:BERF2A-BERF2B(orf name) psi-mi:"MI:0096"(pull down) Robertson et al. (1996) imex:IM-22505|pubmed:8627785 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9258919|imex:IM-22505-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005340.2|refseq:NP_976028.1|refseq:NP_976029.1|refseq:NP_056958.3|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|go:"GO:0030183"(B cell differentiation)|rcsb pdb:2F8X|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:6PY8|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000168214(gene)|ensembl:ENST00000342295(transcript)|ensembl:ENST00000361572(transcript)|ensembl:ENST00000512671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|refseq:XP_005248218.1|refseq:XP_011512142.1|refseq:XP_016863661.1|refseq:XP_016863662.1|refseq:XP_016863663.1|refseq:XP_016863664.1|dip:DIP-33326N dip:DIP-573N|refseq:YP_401670.1|go:"GO:0016032"(viral process)|go:"GO:0042025"(host cell nucleus)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3) - - - figure legend:1C and 3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/03/18 2014/10/16 rogid:K86zd5i5jYfKx0hGupxu8rA8rDM9606 rogid:IpjWARPTNeJa3PZtsGfdgcU37Uo10377 intact-crc:2F8AC2A59930A39D|rigid:AHRjugU6SHp9NDLSPDyCO1Wmh1A false glutathione s tranferase tag:?-? 35s radiolabel:?-?|sufficient binding region:1-311 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P12978 uniprotkb:Q06330 intact:EBI-8052923|uniprotkb:Q777H1|intact:MINT-2576568|uniprotkb:Q69023 intact:EBI-632552|uniprotkb:Q5XKH9|uniprotkb:Q6P1N3|ensembl:ENSP00000345206|ensembl:ENSP00000354528|ensembl:ENSP00000423644|uniprotkb:B4DY22 psi-mi:ebna2_ebvb9(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:suh_human(display_long)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym)|uniprotkb:CBF-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-30(gene name synonym)|uniprotkb:RBPJ(gene name)|psi-mi:RBPJ(display_short)|uniprotkb:IGKJRB(gene name synonym)|uniprotkb:IGKJRB1(gene name synonym)|uniprotkb:RBPJK(gene name synonym)|uniprotkb:RBPSUH(gene name synonym) psi-mi:"MI:0096"(pull down) Robertson et al. (1996) imex:IM-22505|pubmed:8627785 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9258895|imex:IM-22505-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401644.1|mint:P12978|dip:DIP-41174N|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060153"(modulation by virus of host cell cycle)|rcsb pdb:2MKR|rcsb pdb:2N2J|rcsb pdb:5HDA|go:"GO:0019056"(modulation by virus of host transcription) refseq:NP_005340.2|refseq:NP_976028.1|refseq:NP_976029.1|refseq:NP_056958.3|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|go:"GO:0030183"(B cell differentiation)|rcsb pdb:2F8X|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:6PY8|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000168214(gene)|ensembl:ENST00000342295(transcript)|ensembl:ENST00000361572(transcript)|ensembl:ENST00000512671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|refseq:XP_005248218.1|refseq:XP_011512142.1|refseq:XP_016863661.1|refseq:XP_016863662.1|refseq:XP_016863663.1|refseq:XP_016863664.1|dip:DIP-33326N - comment:mint|function:Involved in latent cycle. Transactivates the expression of LMP-1 - figure legend:1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/03/18 2014/10/16 rogid:NFW1UkIAeAdFQXUOC7vT8XKGxes10377 rogid:K86zd5i5jYfKx0hGupxu8rA8rDM9606 intact-crc:0462C82E536D9D51|rigid:drl9QuXzovYgSI2ycpq2Ls9N4bA false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P03204 uniprotkb:Q06330 intact:EBI-9255985|uniprotkb:Q777E7 intact:EBI-632552|uniprotkb:Q5XKH9|uniprotkb:Q6P1N3|ensembl:ENSP00000345206|ensembl:ENSP00000354528|ensembl:ENSP00000423644|uniprotkb:B4DY22 psi-mi:ebna6_ebvb9(display_long)|uniprotkb:EBNA6(gene name)|psi-mi:EBNA6(display_short)|uniprotkb:Epstein-Barr nuclear antigen 3C(gene name synonym)|uniprotkb:Epstein-Barr nuclear antigen 4B(gene name synonym)|uniprotkb:BERF3-BERF4(orf name) psi-mi:suh_human(display_long)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym)|uniprotkb:CBF-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-30(gene name synonym)|uniprotkb:RBPJ(gene name)|psi-mi:RBPJ(display_short)|uniprotkb:IGKJRB(gene name synonym)|uniprotkb:IGKJRB1(gene name synonym)|uniprotkb:RBPJK(gene name synonym)|uniprotkb:RBPSUH(gene name synonym) psi-mi:"MI:0096"(pull down) Robertson et al. (1996) imex:IM-22505|pubmed:8627785 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9258911|imex:IM-22505-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401671.1|dip:DIP-29893N|go:"GO:0019042"(viral latency)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0044204"(host cell nuclear matrix)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|rcsb pdb:1CG9|rcsb pdb:2BSR|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA refseq:NP_005340.2|refseq:NP_976028.1|refseq:NP_976029.1|refseq:NP_056958.3|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|go:"GO:0030183"(B cell differentiation)|rcsb pdb:2F8X|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:6PY8|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000168214(gene)|ensembl:ENST00000342295(transcript)|ensembl:ENST00000361572(transcript)|ensembl:ENST00000512671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|refseq:XP_005248218.1|refseq:XP_011512142.1|refseq:XP_016863661.1|refseq:XP_016863662.1|refseq:XP_016863663.1|refseq:XP_016863664.1|dip:DIP-33326N - - - figure legend:1C and 3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/03/18 2014/10/16 rogid:oVcoM6BNZRp/FFbeZ4QQWq/8vZ410377 rogid:K86zd5i5jYfKx0hGupxu8rA8rDM9606 intact-crc:BC7701F8D6137815|rigid:ZzDM/6pGQf/M0nfy8/J7NGn4OYY false 35s radiolabel:?-?|sufficient binding region:1-183 glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P12977 uniprotkb:Q06330 intact:EBI-993115|uniprotkb:Q66540|uniprotkb:P03202|uniprotkb:Q69021|uniprotkb:Q8AZJ8 intact:EBI-632552|uniprotkb:Q5XKH9|uniprotkb:Q6P1N3|ensembl:ENSP00000345206|ensembl:ENSP00000354528|ensembl:ENSP00000423644|uniprotkb:B4DY22 psi-mi:ebna3_ebvb9(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short) psi-mi:suh_human(display_long)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym)|uniprotkb:CBF-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-30(gene name synonym)|uniprotkb:RBPJ(gene name)|psi-mi:RBPJ(display_short)|uniprotkb:IGKJRB(gene name synonym)|uniprotkb:IGKJRB1(gene name synonym)|uniprotkb:RBPJK(gene name synonym)|uniprotkb:RBPSUH(gene name synonym) psi-mi:"MI:0096"(pull down) Robertson et al. (1996) imex:IM-22505|pubmed:8627785 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9258903|imex:IM-22505-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6VMX|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0044204"(host cell nuclear matrix)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|refseq:YP_401669.1|rcsb pdb:1M05|rcsb pdb:1XR8|rcsb pdb:5WMO refseq:NP_005340.2|refseq:NP_976028.1|refseq:NP_976029.1|refseq:NP_056958.3|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|go:"GO:0030183"(B cell differentiation)|rcsb pdb:2F8X|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:6PY8|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000168214(gene)|ensembl:ENST00000342295(transcript)|ensembl:ENST00000361572(transcript)|ensembl:ENST00000512671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|refseq:XP_005248218.1|refseq:XP_011512142.1|refseq:XP_016863661.1|refseq:XP_016863662.1|refseq:XP_016863663.1|refseq:XP_016863664.1|dip:DIP-33326N - - - figure legend:1C and 3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/03/18 2014/10/16 rogid:0HIls6vxksxriVNTv5M9V6FND8E10377 rogid:K86zd5i5jYfKx0hGupxu8rA8rDM9606 intact-crc:D84E785F11339748|rigid:LrZR/mDcjpTEvKBoG9sJAGDI0wo false 35s radiolabel:?-?|sufficient binding region:1-302 glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q06330 uniprotkb:P12977 intact:EBI-632552|uniprotkb:Q5XKH9|uniprotkb:Q6P1N3|ensembl:ENSP00000345206|ensembl:ENSP00000354528|ensembl:ENSP00000423644|uniprotkb:B4DY22 intact:EBI-993115|uniprotkb:Q66540|uniprotkb:P03202|uniprotkb:Q69021|uniprotkb:Q8AZJ8 psi-mi:suh_human(display_long)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym)|uniprotkb:CBF-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-30(gene name synonym)|uniprotkb:RBPJ(gene name)|psi-mi:RBPJ(display_short)|uniprotkb:IGKJRB(gene name synonym)|uniprotkb:IGKJRB1(gene name synonym)|uniprotkb:RBPJK(gene name synonym)|uniprotkb:RBPSUH(gene name synonym) psi-mi:ebna3_ebvb9(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short) psi-mi:"MI:0096"(pull down) Robertson et al. (1996) imex:IM-22505|pubmed:8627785 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9346381|imex:IM-22505-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005340.2|refseq:NP_976028.1|refseq:NP_976029.1|refseq:NP_056958.3|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|go:"GO:0030183"(B cell differentiation)|rcsb pdb:2F8X|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:6PY8|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000168214(gene)|ensembl:ENST00000342295(transcript)|ensembl:ENST00000361572(transcript)|ensembl:ENST00000512671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|refseq:XP_005248218.1|refseq:XP_011512142.1|refseq:XP_016863661.1|refseq:XP_016863662.1|refseq:XP_016863663.1|refseq:XP_016863664.1|dip:DIP-33326N rcsb pdb:6VMX|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0044204"(host cell nuclear matrix)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|refseq:YP_401669.1|rcsb pdb:1M05|rcsb pdb:1XR8|rcsb pdb:5WMO - - - figure legend:1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/03/18 2014/10/16 rogid:K86zd5i5jYfKx0hGupxu8rA8rDM9606 rogid:0HIls6vxksxriVNTv5M9V6FND8E10377 intact-crc:0BB24532BEEB9235|rigid:LrZR/mDcjpTEvKBoG9sJAGDI0wo false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P03204 uniprotkb:Q06330 intact:EBI-9255985|uniprotkb:Q777E7 intact:EBI-632552|uniprotkb:Q5XKH9|uniprotkb:Q6P1N3|ensembl:ENSP00000345206|ensembl:ENSP00000354528|ensembl:ENSP00000423644|uniprotkb:B4DY22 psi-mi:ebna6_ebvb9(display_long)|uniprotkb:EBNA6(gene name)|psi-mi:EBNA6(display_short)|uniprotkb:Epstein-Barr nuclear antigen 3C(gene name synonym)|uniprotkb:Epstein-Barr nuclear antigen 4B(gene name synonym)|uniprotkb:BERF3-BERF4(orf name) psi-mi:suh_human(display_long)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym)|uniprotkb:CBF-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-30(gene name synonym)|uniprotkb:RBPJ(gene name)|psi-mi:RBPJ(display_short)|uniprotkb:IGKJRB(gene name synonym)|uniprotkb:IGKJRB1(gene name synonym)|uniprotkb:RBPJK(gene name synonym)|uniprotkb:RBPSUH(gene name synonym) psi-mi:"MI:0096"(pull down) Robertson et al. (1996) imex:IM-22505|pubmed:8627785 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9346375|imex:IM-22505-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401671.1|dip:DIP-29893N|go:"GO:0019042"(viral latency)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0044204"(host cell nuclear matrix)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|rcsb pdb:1CG9|rcsb pdb:2BSR|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA refseq:NP_005340.2|refseq:NP_976028.1|refseq:NP_976029.1|refseq:NP_056958.3|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|go:"GO:0030183"(B cell differentiation)|rcsb pdb:2F8X|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:6PY8|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000168214(gene)|ensembl:ENST00000342295(transcript)|ensembl:ENST00000361572(transcript)|ensembl:ENST00000512671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|refseq:XP_005248218.1|refseq:XP_011512142.1|refseq:XP_016863661.1|refseq:XP_016863662.1|refseq:XP_016863663.1|refseq:XP_016863664.1|dip:DIP-33326N - - - figure legend:1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/03/18 2014/10/16 rogid:oVcoM6BNZRp/FFbeZ4QQWq/8vZ410377 rogid:K86zd5i5jYfKx0hGupxu8rA8rDM9606 intact-crc:C9DD6A0294103754|rigid:ZzDM/6pGQf/M0nfy8/J7NGn4OYY false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P03203 uniprotkb:Q06330 intact:EBI-9346250|uniprotkb:Q777E8 intact:EBI-632552|uniprotkb:Q5XKH9|uniprotkb:Q6P1N3|ensembl:ENSP00000345206|ensembl:ENSP00000354528|ensembl:ENSP00000423644|uniprotkb:B4DY22 psi-mi:ebna4_ebvb9(display_long)|uniprotkb:EBNA4(gene name)|psi-mi:EBNA4(display_short)|uniprotkb:Epstein-Barr nuclear antigen 3B(gene name synonym)|uniprotkb:BERF2A-BERF2B(orf name) psi-mi:suh_human(display_long)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym)|uniprotkb:CBF-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-30(gene name synonym)|uniprotkb:RBPJ(gene name)|psi-mi:RBPJ(display_short)|uniprotkb:IGKJRB(gene name synonym)|uniprotkb:IGKJRB1(gene name synonym)|uniprotkb:RBPJK(gene name synonym)|uniprotkb:RBPSUH(gene name synonym) psi-mi:"MI:0096"(pull down) Robertson et al. (1996) imex:IM-22505|pubmed:8627785 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9346379|imex:IM-22505-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-573N|refseq:YP_401670.1|go:"GO:0016032"(viral process)|go:"GO:0042025"(host cell nucleus)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3) refseq:NP_005340.2|refseq:NP_976028.1|refseq:NP_976029.1|refseq:NP_056958.3|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|go:"GO:0030183"(B cell differentiation)|rcsb pdb:2F8X|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:6PY8|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000168214(gene)|ensembl:ENST00000342295(transcript)|ensembl:ENST00000361572(transcript)|ensembl:ENST00000512671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|refseq:XP_005248218.1|refseq:XP_011512142.1|refseq:XP_016863661.1|refseq:XP_016863662.1|refseq:XP_016863663.1|refseq:XP_016863664.1|dip:DIP-33326N - - - figure legend:1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/03/18 2014/10/16 rogid:IpjWARPTNeJa3PZtsGfdgcU37Uo10377 rogid:K86zd5i5jYfKx0hGupxu8rA8rDM9606 intact-crc:BCAE97F9E2B933A8|rigid:AHRjugU6SHp9NDLSPDyCO1Wmh1A false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06330 uniprotkb:P03203 intact:EBI-632552|uniprotkb:Q5XKH9|uniprotkb:Q6P1N3|ensembl:ENSP00000345206|ensembl:ENSP00000354528|ensembl:ENSP00000423644|uniprotkb:B4DY22 intact:EBI-9346250|uniprotkb:Q777E8 psi-mi:suh_human(display_long)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym)|uniprotkb:CBF-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-30(gene name synonym)|uniprotkb:RBPJ(gene name)|psi-mi:RBPJ(display_short)|uniprotkb:IGKJRB(gene name synonym)|uniprotkb:IGKJRB1(gene name synonym)|uniprotkb:RBPJK(gene name synonym)|uniprotkb:RBPSUH(gene name synonym) psi-mi:ebna4_ebvb9(display_long)|uniprotkb:EBNA4(gene name)|psi-mi:EBNA4(display_short)|uniprotkb:Epstein-Barr nuclear antigen 3B(gene name synonym)|uniprotkb:BERF2A-BERF2B(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Robertson et al. (1996) imex:IM-22505|pubmed:8627785 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9346597|imex:IM-22505-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005340.2|refseq:NP_976028.1|refseq:NP_976029.1|refseq:NP_056958.3|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|go:"GO:0030183"(B cell differentiation)|rcsb pdb:2F8X|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:6PY8|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000168214(gene)|ensembl:ENST00000342295(transcript)|ensembl:ENST00000361572(transcript)|ensembl:ENST00000512671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|refseq:XP_005248218.1|refseq:XP_011512142.1|refseq:XP_016863661.1|refseq:XP_016863662.1|refseq:XP_016863663.1|refseq:XP_016863664.1|dip:DIP-33326N dip:DIP-573N|refseq:YP_401670.1|go:"GO:0016032"(viral process)|go:"GO:0042025"(host cell nucleus)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3) - - - figure legend:2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-bjab)|taxid:9606(Homo sapiens B-cell lymphoma cell line) - 2014/03/18 2014/10/16 rogid:K86zd5i5jYfKx0hGupxu8rA8rDM9606 rogid:IpjWARPTNeJa3PZtsGfdgcU37Uo10377 intact-crc:6BAD29D02593A027|rigid:AHRjugU6SHp9NDLSPDyCO1Wmh1A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06330 uniprotkb:P12977 intact:EBI-632552|uniprotkb:Q5XKH9|uniprotkb:Q6P1N3|ensembl:ENSP00000345206|ensembl:ENSP00000354528|ensembl:ENSP00000423644|uniprotkb:B4DY22 intact:EBI-993115|uniprotkb:Q66540|uniprotkb:P03202|uniprotkb:Q69021|uniprotkb:Q8AZJ8 psi-mi:suh_human(display_long)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym)|uniprotkb:CBF-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-30(gene name synonym)|uniprotkb:RBPJ(gene name)|psi-mi:RBPJ(display_short)|uniprotkb:IGKJRB(gene name synonym)|uniprotkb:IGKJRB1(gene name synonym)|uniprotkb:RBPJK(gene name synonym)|uniprotkb:RBPSUH(gene name synonym) psi-mi:ebna3_ebvb9(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Robertson et al. (1996) imex:IM-22505|pubmed:8627785 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9346601|imex:IM-22505-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005340.2|refseq:NP_976028.1|refseq:NP_976029.1|refseq:NP_056958.3|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|go:"GO:0030183"(B cell differentiation)|rcsb pdb:2F8X|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:6PY8|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000168214(gene)|ensembl:ENST00000342295(transcript)|ensembl:ENST00000361572(transcript)|ensembl:ENST00000512671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|refseq:XP_005248218.1|refseq:XP_011512142.1|refseq:XP_016863661.1|refseq:XP_016863662.1|refseq:XP_016863663.1|refseq:XP_016863664.1|dip:DIP-33326N rcsb pdb:6VMX|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0044204"(host cell nuclear matrix)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|refseq:YP_401669.1|rcsb pdb:1M05|rcsb pdb:1XR8|rcsb pdb:5WMO - - - figure legend:2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-bjab)|taxid:9606(Homo sapiens B-cell lymphoma cell line) - 2014/03/18 2014/10/16 rogid:K86zd5i5jYfKx0hGupxu8rA8rDM9606 rogid:0HIls6vxksxriVNTv5M9V6FND8E10377 intact-crc:424A6E5631C3114A|rigid:LrZR/mDcjpTEvKBoG9sJAGDI0wo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P12978 uniprotkb:Q06330 intact:EBI-8052923|uniprotkb:Q777H1|intact:MINT-2576568|uniprotkb:Q69023 intact:EBI-632552|uniprotkb:Q5XKH9|uniprotkb:Q6P1N3|ensembl:ENSP00000345206|ensembl:ENSP00000354528|ensembl:ENSP00000423644|uniprotkb:B4DY22 psi-mi:ebna2_ebvb9(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:suh_human(display_long)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym)|uniprotkb:CBF-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-30(gene name synonym)|uniprotkb:RBPJ(gene name)|psi-mi:RBPJ(display_short)|uniprotkb:IGKJRB(gene name synonym)|uniprotkb:IGKJRB1(gene name synonym)|uniprotkb:RBPJK(gene name synonym)|uniprotkb:RBPSUH(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Robertson et al. (1996) imex:IM-22505|pubmed:8627785 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9346595|imex:IM-22505-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401644.1|mint:P12978|dip:DIP-41174N|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060153"(modulation by virus of host cell cycle)|rcsb pdb:2MKR|rcsb pdb:2N2J|rcsb pdb:5HDA|go:"GO:0019056"(modulation by virus of host transcription) refseq:NP_005340.2|refseq:NP_976028.1|refseq:NP_976029.1|refseq:NP_056958.3|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|go:"GO:0030183"(B cell differentiation)|rcsb pdb:2F8X|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:6PY8|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000168214(gene)|ensembl:ENST00000342295(transcript)|ensembl:ENST00000361572(transcript)|ensembl:ENST00000512671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|refseq:XP_005248218.1|refseq:XP_011512142.1|refseq:XP_016863661.1|refseq:XP_016863662.1|refseq:XP_016863663.1|refseq:XP_016863664.1|dip:DIP-33326N - comment:mint|function:Involved in latent cycle. Transactivates the expression of LMP-1 - figure legend:2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-bjab)|taxid:9606(Homo sapiens B-cell lymphoma cell line) - 2014/03/18 2014/10/16 rogid:NFW1UkIAeAdFQXUOC7vT8XKGxes10377 rogid:K86zd5i5jYfKx0hGupxu8rA8rDM9606 intact-crc:437B6EF95CD95315|rigid:drl9QuXzovYgSI2ycpq2Ls9N4bA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P03204 uniprotkb:Q06330 intact:EBI-9255985|uniprotkb:Q777E7 intact:EBI-632552|uniprotkb:Q5XKH9|uniprotkb:Q6P1N3|ensembl:ENSP00000345206|ensembl:ENSP00000354528|ensembl:ENSP00000423644|uniprotkb:B4DY22 psi-mi:ebna6_ebvb9(display_long)|uniprotkb:EBNA6(gene name)|psi-mi:EBNA6(display_short)|uniprotkb:Epstein-Barr nuclear antigen 3C(gene name synonym)|uniprotkb:Epstein-Barr nuclear antigen 4B(gene name synonym)|uniprotkb:BERF3-BERF4(orf name) psi-mi:suh_human(display_long)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym)|uniprotkb:CBF-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-30(gene name synonym)|uniprotkb:RBPJ(gene name)|psi-mi:RBPJ(display_short)|uniprotkb:IGKJRB(gene name synonym)|uniprotkb:IGKJRB1(gene name synonym)|uniprotkb:RBPJK(gene name synonym)|uniprotkb:RBPSUH(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Robertson et al. (1996) imex:IM-22505|pubmed:8627785 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9346599|imex:IM-22505-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401671.1|dip:DIP-29893N|go:"GO:0019042"(viral latency)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0044204"(host cell nuclear matrix)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|rcsb pdb:1CG9|rcsb pdb:2BSR|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA refseq:NP_005340.2|refseq:NP_976028.1|refseq:NP_976029.1|refseq:NP_056958.3|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|go:"GO:0030183"(B cell differentiation)|rcsb pdb:2F8X|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:6PY8|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000168214(gene)|ensembl:ENST00000342295(transcript)|ensembl:ENST00000361572(transcript)|ensembl:ENST00000512671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|refseq:XP_005248218.1|refseq:XP_011512142.1|refseq:XP_016863661.1|refseq:XP_016863662.1|refseq:XP_016863663.1|refseq:XP_016863664.1|dip:DIP-33326N - - - figure legend:2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-bjab)|taxid:9606(Homo sapiens B-cell lymphoma cell line) - 2014/03/18 2014/10/16 rogid:oVcoM6BNZRp/FFbeZ4QQWq/8vZ410377 rogid:K86zd5i5jYfKx0hGupxu8rA8rDM9606 intact-crc:263786C606B96626|rigid:ZzDM/6pGQf/M0nfy8/J7NGn4OYY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)