#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:16356"	uniprotkb:Q13976	intact:EBI-8766547|chebi:"CHEBI:488479"|chebi:"CHEBI:1327"|chebi:"CHEBI:11675"|chebi:"CHEBI:14377"|chebi:"CHEBI:19829"	intact:EBI-3952014|uniprotkb:Q6P5T7|uniprotkb:E2PU10|uniprotkb:P14619|uniprotkb:Q5JSJ6|ensembl:ENSP00000384200|uniprotkb:A5YM56|uniprotkb:B3KSF3|uniprotkb:Q5JP05	psi-mi:3',5'-cyclic gmp(display_short)|psi-mi:"CHEBI:16356"(display_long)|intact:3',5'-Cyclic GMP(synonym)|intact:cGMP(synonym)|intact:Cyclic GMP(synonym)|intact:Guanosine 3',5'-cyclic monophosphate(synonym)|intact:Guanosine 3',5'-cyclic phosphate(synonym)|intact:Guanosine cyclic monophosphate(synonym)|intact:"guanosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:kgp1_human(display_long)|uniprotkb:PRKG1(gene name)|psi-mi:PRKG1(display_short)|uniprotkb:PRKG1B(gene name synonym)|uniprotkb:PRKGR1A(gene name synonym)|uniprotkb:PRKGR1B(gene name synonym)|uniprotkb:cGMP-dependent protein kinase I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094148|imex:IM-23267-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR018488|interpro:IPR018490|interpro:IPR031831|interpro:IPR035014|mint:Q13976|rcsb pdb:1ZXA|rcsb pdb:3NMD|rcsb pdb:3OCP|rcsb pdb:3OD0|rcsb pdb:3OGJ|rcsb pdb:4KU7|rcsb pdb:4KU8|rcsb pdb:4QX5|rcsb pdb:4QXK|rcsb pdb:4R4L|rcsb pdb:4R4M|rcsb pdb:4Z07|rcsb pdb:5J48|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5JAX|rcsb pdb:5JD7|rcsb pdb:5L0N|rcsb pdb:6BDL|rcsb pdb:6BG2|rcsb pdb:6C0T|reactome:R-HSA-392517|reactome:R-HSA-4086398|reactome:R-HSA-418457|refseq:NP_001091982.1|refseq:NP_006249.1|ensembl:ENST00000401604(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004692"(cGMP-dependent protein kinase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016358"(dendrite development)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030553"(cGMP binding)|go:"GO:0030900"(forebrain development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002374(cGMP-dependent protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014710(RmlC-like jelly roll fold)|ensembl:ENSG00000185532(gene)|dip:DIP-41118N|dip:DIP-46288N	-	inchi key:ZOOGRGPOEVQQDX-UUOKFMHZSA-N	caution:This sequence has been withdrawn from Uniprot.|crc64:51389502A5E5FBD2	figure legend:Table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2015/01/22	-	rogid:FFagskyghjyYPihsoL8JaO0RXgY9606	intact-crc:C530E12115DD2C16	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P10644	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-476431|uniprotkb:Q567S7|uniprotkb:K7ER48|ensembl:ENSP00000351410|ensembl:ENSP00000376475|ensembl:ENSP00000445625|ensembl:ENSP00000464977|ensembl:ENSP00000466459	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094170|imex:IM-23267-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|dip:DIP-34368N|ensembl:ENSG00000108946(gene)|ensembl:ENST00000358598(transcript)|ensembl:ENST00000392711(transcript)|ensembl:ENST00000536854(transcript)|ensembl:ENST00000586397(transcript)|ensembl:ENST00000589228(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|interpro:IPR018490|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY	-	-	-	figure legend:Table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2018/04/30	-	rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606	intact-crc:FF84243C517C8DB9	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:Q5VU43	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094170|imex:IM-23267-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N	-	-	-	figure legend:Table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2018/04/30	-	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	intact-crc:FF84243C517C8DB9	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:Q9UKA4	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-1049491|uniprotkb:O75124|uniprotkb:Q9NUK7|ensembl:ENSP00000025301	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:aka11_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 11(gene name synonym)|uniprotkb:A-kinase anchor protein 220 kDa(gene name synonym)|uniprotkb:AKAP11(gene name)|psi-mi:AKAP11(display_short)|uniprotkb:AKAP220(gene name synonym)|uniprotkb:KIAA0629(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094170|imex:IM-23267-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011533205.1|refseq:XP_011533206.1|refseq:XP_011533207.1|refseq:XP_011533208.1|refseq:NP_057332.1|refseq:XP_016875870.1|ensembl:ENSG00000023516(gene)|ensembl:ENST00000025301(transcript)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008104"(protein localization)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0051018"(protein kinase A binding)|interpro:IPR008382(A-kinase anchor 110 kDa)|mint:Q9UKA4	-	-	-	figure legend:Table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2018/04/30	-	rogid:EoQOZuPirXCY2k5migb2Fr6utZ09606	intact-crc:FF84243C517C8DB9	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P31321	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-2805516|uniprotkb:Q8N422|ensembl:ENSP00000353415|ensembl:ENSP00000385349|ensembl:ENSP00000385749|ensembl:ENSP00000440449|ensembl:ENSP00000444487	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:kap1_human(display_long)|uniprotkb:PRKAR1B(gene name)|psi-mi:PRKAR1B(display_short)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094170|imex:IM-23267-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001158230.1|refseq:NP_001158231.1|refseq:NP_001158232.1|refseq:NP_001158233.1|refseq:NP_001158234.1|refseq:NP_002726.1|ensembl:ENSG00000188191(gene)|ensembl:ENST00000360274(transcript)|ensembl:ENST00000403562(transcript)|ensembl:ENST00000406797(transcript)|ensembl:ENST00000537384(transcript)|ensembl:ENST00000544935(transcript)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007611"(learning or memory)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0097546"(ciliary base)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|interpro:IPR042818|rcsb pdb:4DIN|rcsb pdb:4F9K|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)	-	-	-	figure legend:Table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2018/04/30	-	rogid:lHJ5CQLoIXsPDtmgJgb34zho6B89606	intact-crc:FF84243C517C8DB9	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:Q99996	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-1048311|uniprotkb:O14869|uniprotkb:O43355|uniprotkb:O94895|uniprotkb:Q75N20|uniprotkb:Q9UQH3|uniprotkb:Q9UQQ4|uniprotkb:Q9Y6B8|uniprotkb:A4D1F0|uniprotkb:Q9Y6Y2|uniprotkb:A4D1F2|uniprotkb:A4D1F4|ensembl:ENSP00000348573	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:akap9_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 9(gene name synonym)|uniprotkb:A-kinase anchor protein 450 kDa(gene name synonym)|uniprotkb:A-kinase anchor protein 350 kDa(gene name synonym)|uniprotkb:AKAP 120-like protein(gene name synonym)|uniprotkb:Protein hyperion(gene name synonym)|uniprotkb:Protein yotiao(gene name synonym)|uniprotkb:Centrosome- and Golgi-localized PKN-associated protein(gene name synonym)|uniprotkb:AKAP9(gene name)|psi-mi:AKAP9(display_short)|uniprotkb:AKAP350(gene name synonym)|uniprotkb:AKAP450(gene name synonym)|uniprotkb:KIAA0803(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094170|imex:IM-23267-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005742.4|refseq:NP_671714.1|ensembl:ENSG00000127914(gene)|ensembl:ENST00000356239(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007165"(signal transduction)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0034705"(potassium channel complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044307"(dendritic branch)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR005539(ELK)|interpro:IPR019528|interpro:IPR028745|mint:Q99996|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5576890|reactome:R-HSA-5576893|reactome:R-HSA-5620912|reactome:R-HSA-6802952|reactome:R-HSA-8854518|ensembl:ENSP00000348573|ensembl:ENST00000680766|ensembl:ENSP00000505204|dip:DIP-29942N	-	-	-	figure legend:Table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2018/04/30	-	rogid:LQUNbTHUgEsjayFEZvczC4e90Nw9606	intact-crc:FF84243C517C8DB9	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:Q9Y2D5	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-1754555|uniprotkb:Q9UG26|uniprotkb:B1ALX9|uniprotkb:B2RTU4|uniprotkb:B3KQ00|uniprotkb:B4DTZ2|uniprotkb:B7ZW07|uniprotkb:B9EJB5	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:akap2_human(display_long)|uniprotkb:AKAP2(gene name)|psi-mi:AKAP2(display_short)|uniprotkb:KIAA0920(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 2(gene name synonym)|uniprotkb:AKAP-KL(gene name synonym)|uniprotkb:PRKA2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094170|imex:IM-23267-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001004065.2|refseq:NP_001130034.1|refseq:NP_001185585.1|refseq:NP_009134.1|refseq:NP_671492.1|interpro:IPR029304	-	-	-	figure legend:Table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2018/04/30	-	rogid:xfHb6tD0ToXJPHpl4MlbKczjzSg9606	intact-crc:FF84243C517C8DB9	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:Q92667	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736|ensembl:ENSP00000443139|ensembl:ENSP00000459895|ensembl:ENSP00000459968|ensembl:ENSP00000478212	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094170|imex:IM-23267-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|ensembl:ENSG00000121057(gene)|ensembl:ENST00000337714(transcript)|ensembl:ENST00000539273(transcript)|ensembl:ENST00000571629(transcript)|ensembl:ENST00000572557(transcript)|ensembl:ENST00000621116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231	-	-	-	figure legend:Table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2018/04/30	-	rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606	intact-crc:FF84243C517C8DB9	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P11137	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-2682460|uniprotkb:Q17S04|uniprotkb:Q99975|uniprotkb:Q99976|uniprotkb:Q8IUX2|ensembl:ENSP00000353508|ensembl:ENSP00000507035	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:mtap2_human(display_long)|uniprotkb:MAP2(gene name)|psi-mi:MAP2(display_short)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094170|imex:IM-23267-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002365.3|refseq:NP_114033.2|refseq:NP_114035.2|refseq:NP_001034627.1|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1903744"(positive regulation of anterograde synaptic vesicle transport)|go:"GO:1903827"|go:"GO:1904527"(negative regulation of microtubule binding)|go:"GO:1990635"(proximal dendrite)|go:"GO:1990769"(proximal neuron projection)|go:"GO:2000575"(obsolete negative regulation of microtubule motor activity)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR013588(MAP2/Tau projection)|interpro:IPR030797|mint:P11137|ensembl:ENSG00000078018(gene)|ensembl:ENST00000360351(transcript)|ensembl:ENST00000682079(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0008017"(microtubule binding)|go:"GO:0016358"(dendrite development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030425"(dendrite)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043203"(axon hillock)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044307"(dendritic branch)|go:"GO:0048156"(tau protein binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0097441"(basal dendrite)|go:"GO:0150001"(primary dendrite)|go:"GO:0150002"(distal dendrite)|go:"GO:0150014"(apical distal dendrite)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|refseq:XP_016859607.1|refseq:XP_016859612.1|refseq:XP_016859613.1|refseq:XP_016859627.1|refseq:XP_016859628.1|dip:DIP-577N|refseq:XP_016859629.1	-	-	-	figure legend:Table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2018/04/30	-	rogid:IfbwC7748mUgLEmuxR5Zd2TEQ/09606	intact-crc:FF84243C517C8DB9	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:Q12802	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-1373806|uniprotkb:Q14572|uniprotkb:Q59FP6|uniprotkb:Q86W90|uniprotkb:Q8WXQ6|uniprotkb:Q96JP6|uniprotkb:Q96P79|uniprotkb:Q9Y5T0|uniprotkb:Q9Y5T6|intact:EBI-28978093|ensembl:ENSP00000378026	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:akp13_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 13(gene name synonym)|uniprotkb:Breast cancer nuclear receptor-binding auxiliary protein(gene name synonym)|uniprotkb:Human thyroid-anchoring protein 31(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor Lbc(gene name synonym)|uniprotkb:AKAP-Lbc(gene name synonym)|uniprotkb:p47(gene name synonym)|uniprotkb:Lymphoid blast crisis oncogene(gene name synonym)|uniprotkb:Non-oncogenic Rho GTPase-specific GTP exchange factor(gene name synonym)|uniprotkb:AKAP13(gene name)|psi-mi:AKAP13(display_short)|uniprotkb:BRX(gene name synonym)|uniprotkb:HT31(gene name synonym)|uniprotkb:LBC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094170|imex:IM-23267-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006729.4|refseq:NP_009131.2|ensembl:ENST00000361243|ensembl:ENSP00000354718|ensembl:ENSP00000378026|ensembl:ENST00000560302|ensembl:ENSP00000453634|refseq:NP_001257475.1|dip:DIP-180N|ensembl:ENSG00000170776(gene)|ensembl:ENST00000394518(transcript)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051168"(nuclear export)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060348"(bone development)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0086023"(adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018459|interpro:IPR028852|interpro:IPR035899|interpro:IPR041020|mint:Q12802|rcsb pdb:2DRN|rcsb pdb:2LG1|rcsb pdb:4D0N|rcsb pdb:4D0O|rcsb pdb:6BCA|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106	-	-	-	figure legend:Table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2018/04/30	-	rogid:pHHpKUh10J/O/fp06k4NaNhJF6U9606	intact-crc:FF84243C517C8DB9	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:Q8WZA2	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-948476|ensembl:ENSP00000380271|uniprotkb:O95636|uniprotkb:Q8IXK6|uniprotkb:Q8TAA4|uniprotkb:B2R7R3|uniprotkb:B7Z912|uniprotkb:B7Z283|uniprotkb:B7Z3T6	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:rpgf4_human(display_long)|uniprotkb:cAMP-regulated guanine nucleotide exchange factor II(gene name synonym)|uniprotkb:Exchange factor directly activated by cAMP 2(gene name synonym)|uniprotkb:Exchange protein directly activated by cAMP 2(gene name synonym)|uniprotkb:RAPGEF4(gene name)|psi-mi:RAPGEF4(display_short)|uniprotkb:CGEF2(gene name synonym)|uniprotkb:EPAC2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094170|imex:IM-23267-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001269828.1|refseq:NP_001269829.1|refseq:NP_001269830.1|ensembl:ENSG00000091428(gene)|ensembl:ENST00000397081(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030552"(cAMP binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036388|interpro:IPR036390|interpro:IPR036964|reactome:R-HSA-354192|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|refseq:NP_001093867.1|refseq:NP_008954.2|refseq:XP_006712268.1	-	-	-	figure legend:Table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2018/04/30	-	rogid:cYq6CkJ34txlv5XggTyHhvQvcEw9606	intact-crc:FF84243C517C8DB9	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:Q9P0M2	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-2512902|ensembl:ENSP00000405252|uniprotkb:Q9HCZ8|uniprotkb:B4DUC3	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:aka7g_human(display_long)|uniprotkb:AKAP7(gene name)|psi-mi:AKAP7(display_short)|uniprotkb:AKAP18(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 7 isoform gamma(gene name synonym)|uniprotkb:A-kinase anchor protein 18 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094170|imex:IM-23267-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000118507(gene)|ensembl:ENST00000431975(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR019510|interpro:IPR019511|rcsb pdb:4ZP3|rcsb pdb:5JJ2|refseq:NP_057461.2	-	-	-	figure legend:Table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2018/04/30	-	rogid:BCt7xqbd+kGycJeocp3Q/m+mbV89606	intact-crc:FF84243C517C8DB9	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P31323	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-2930670|ensembl:ENSP00000265717|ensembl:ENSP00000491687|uniprotkb:A4D0R9	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:kap3_human(display_long)|uniprotkb:PRKAR2B(gene name)|psi-mi:PRKAR2B(display_short)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094170|imex:IM-23267-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000005249(gene)|ensembl:ENSG00000284096(gene)|ensembl:ENST00000265717(transcript)|ensembl:ENST00000639737(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0007612"(learning)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P31323|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|refseq:NP_002727.2|dip:DIP-554N	-	-	-	figure legend:Table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2018/04/30	-	rogid:P643dCCYtpt/EkR7tmZrbo97FLE9606	intact-crc:FF84243C517C8DB9	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P13861	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-2556122|intact:EBI-6116682|uniprotkb:Q9BUB1|uniprotkb:Q16823|ensembl:ENSP00000265563|ensembl:ENSP00000394041|intact:EBI-10961724	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094170|imex:IM-23267-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	dip:DIP-552N|refseq:XP_011532244.1|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|ensembl:ENSG00000114302(gene)|ensembl:ENST00000265563(transcript)|ensembl:ENST00000454963(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097546"(ciliary base)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:NP_004148.1|refseq:XP_016862304.1	-	-	-	figure legend:Table 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2018/04/30	-	rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606	intact-crc:FF84243C517C8DB9	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:16356"	uniprotkb:D3ZDF3	intact:EBI-8766547|chebi:"CHEBI:488479"|chebi:"CHEBI:1327"|chebi:"CHEBI:11675"|chebi:"CHEBI:14377"|chebi:"CHEBI:19829"	intact:EBI-6122071|ensembl:ENSRNOP00000024060	psi-mi:3',5'-cyclic gmp(display_short)|psi-mi:"CHEBI:16356"(display_long)|intact:3',5'-Cyclic GMP(synonym)|intact:cGMP(synonym)|intact:Cyclic GMP(synonym)|intact:Guanosine 3',5'-cyclic monophosphate(synonym)|intact:Guanosine 3',5'-cyclic phosphate(synonym)|intact:Guanosine cyclic monophosphate(synonym)|intact:"guanosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:d3zdf3_rat(display_long)|uniprotkb:Mrvi1(gene name)|psi-mi:Mrvi1(display_short)|uniprotkb:Mrvi1_predicted(gene name synonym)|uniprotkb:rCG_39289(orf name)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094207|imex:IM-23267-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_008757950.1|refseq:XP_008757951.1|refseq:XP_006230109.1|rgd:1309828|refseq:NP_001098680.1|refseq:XP_017444686.1|ensembl:ENSRNOG00000017767(gene)|ensembl:ENSRNOT00000024060(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|interpro:IPR008677(MRVI1)|reactome:R-RNO-418457|ipi:IPI00368515.3(identity)	-	inchi key:ZOOGRGPOEVQQDX-UUOKFMHZSA-N	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2015/01/22	-	rogid:k5Hc75fLoo38PmwFF9Lp7xAvERg10116	intact-crc:5AF3CD2E563E5365	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:16356"	uniprotkb:A9LNM8	intact:EBI-8766547|chebi:"CHEBI:488479"|chebi:"CHEBI:1327"|chebi:"CHEBI:11675"|chebi:"CHEBI:14377"|chebi:"CHEBI:19829"	intact:EBI-10094209	psi-mi:3',5'-cyclic gmp(display_short)|psi-mi:"CHEBI:16356"(display_long)|intact:3',5'-Cyclic GMP(synonym)|intact:cGMP(synonym)|intact:Cyclic GMP(synonym)|intact:Guanosine 3',5'-cyclic monophosphate(synonym)|intact:Guanosine 3',5'-cyclic phosphate(synonym)|intact:Guanosine cyclic monophosphate(synonym)|intact:"guanosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:a9lnm8_rat(display_long)|uniprotkb:Pkg(gene name)|psi-mi:Pkg(display_short)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094207|imex:IM-23267-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR031831|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002374(cGMP-dependent protein kinase, core)|interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0004692"(cGMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0030553"(cGMP binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR035014|ipi:IPI00870747.2(identity)	-	inchi key:ZOOGRGPOEVQQDX-UUOKFMHZSA-N	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2015/01/22	-	rogid:wXZSF3CcdSpL7A0D/OuoPvUSgHs10116	intact-crc:5AF3CD2E563E5365	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:16356"	uniprotkb:P54256-2	intact:EBI-8766547|chebi:"CHEBI:488479"|chebi:"CHEBI:1327"|chebi:"CHEBI:11675"|chebi:"CHEBI:14377"|chebi:"CHEBI:19829"	intact:EBI-994554	psi-mi:3',5'-cyclic gmp(display_short)|psi-mi:"CHEBI:16356"(display_long)|intact:3',5'-Cyclic GMP(synonym)|intact:cGMP(synonym)|intact:Cyclic GMP(synonym)|intact:Guanosine 3',5'-cyclic monophosphate(synonym)|intact:Guanosine 3',5'-cyclic phosphate(synonym)|intact:Guanosine cyclic monophosphate(synonym)|intact:"guanosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:p54256-2(display_long)|uniprotkb:Short(isoform synonym)|uniprotkb:Hap1(gene name)|psi-mi:Hap1(display_short)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094207|imex:IM-23267-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	intact:EBI-994539(hap1_rat)|ipi:IPI00231413.1(identity)	-	inchi key:ZOOGRGPOEVQQDX-UUOKFMHZSA-N	isoform-comment:Contains a phosphothreonine at position 598.	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2015/01/22	-	rogid:wybvRRwigIlRInTvs3WtFsSmFkc10116	intact-crc:5AF3CD2E563E5365	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P68182	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-400695|uniprotkb:P05206|ensembl:ENSRNOP00000062228	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:kapcb_rat(display_long)|uniprotkb:Prkacb(gene name)|psi-mi:Prkacb(display_short)|uniprotkb:Pkacb(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:1310574|refseq:NP_001071113.1|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000719(Protein kinase, core)|ensembl:ENSRNOG00000004978(gene)|ensembl:ENSRNOT00000068739(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|reactome:R-RNO-163615|reactome:R-RNO-164378|reactome:R-RNO-180024|reactome:R-RNO-381676|reactome:R-RNO-392517|reactome:R-RNO-422356|reactome:R-RNO-432040|reactome:R-RNO-4420097|reactome:R-RNO-442720|reactome:R-RNO-5610785|reactome:R-RNO-5610787|reactome:R-RNO-5687128|reactome:R-RNO-8853659|reactome:R-RNO-8963896|reactome:R-RNO-983231|ipi:IPI00948594.1(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:9278c8xZsjU90+vryXpzUc0y/G010116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P0C6C0	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-10094368	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:spkap_rat(display_long)|uniprotkb:Sphkap(gene name)|psi-mi:Sphkap(display_short)|uniprotkb:Skip(gene name synonym)|uniprotkb:SPHK1-interactor and AKAP domain-containing protein(gene name synonym)|uniprotkb:Sphingosine kinase type 1-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR018292|interpro:IPR008382(A-kinase anchor 110 kDa)|rgd:1311951|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0030018"(Z disc)|go:"GO:0051018"(protein kinase A binding)|ipi:IPI00948267.1(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:nOdE5Hm/4Llo96F0TAme2wLvBdw10116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:Q8K4S6	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-10094348	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:q8k4s6_rat(display_long)|uniprotkb:cg-nap(gene name)|psi-mi:cg-nap(display_short)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR028745|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0007165"(signal transduction)|go:"GO:0060090"(molecular adaptor activity)|ipi:IPI00948086.1(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:i5lxMliWMAtVv6NjAUzR6K5kTJs10116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:D3ZS99	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-6095676|ensembl:ENSRNOP00000054952	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:d3zs99_rat(display_long)|uniprotkb:Akap11(gene name)|psi-mi:Akap11(display_short)|uniprotkb:LOC498549(gene name synonym)|uniprotkb:rCG_37199(orf name)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_036905.2|rgd:2079|ensembl:ENSRNOG00000009987(gene)|ensembl:ENSRNOT00000058148(transcript)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0036010"(protein localization to endosome)|interpro:IPR008382(A-kinase anchor 110 kDa)|ipi:IPI00779281.3(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:aQaqAKZZLkop5geT2vPdcxqbuuY10116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:Q6JP77	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-6096191|uniprotkb:D3ZMQ5	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:aka7g_rat(display_long)|uniprotkb:Akap7(gene name)|psi-mi:Akap7(display_short)|uniprotkb:A-kinase anchor protein 18(gene name synonym)|uniprotkb:AKAP-18(gene name synonym)|uniprotkb:Akap18(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 7 isoforms delta and gamma(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	mint:Q6JP77|rgd:1303071|refseq:NP_001001801.1|interpro:IPR019510|interpro:IPR019511|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030315"(T-tubule)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|rcsb pdb:2VFK|rcsb pdb:2VFL|rcsb pdb:2VFY|rcsb pdb:3J4Q|rcsb pdb:3J4R|ipi:IPI00767226.1(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:sSbqSwGJRZSWKrpe4GgdME6TVNU10116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:Q9JHE0	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-10094324	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:q9jhe0_rat(display_long)|uniprotkb:yotiao(gene name)|psi-mi:yotiao(display_short)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR028745|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0007165"(signal transduction)|go:"GO:0060090"(molecular adaptor activity)|ipi:IPI00560333.1(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:ZmlmDREkciKi4OfmvoW+3SyMqWM10116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P12369	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-6096160|ensembl:ENSRNOP00000012415	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:kap3_rat(display_long)|uniprotkb:Prkar2b(gene name)|psi-mi:Prkar2b(display_short)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3394|refseq:NP_001025191.1|dip:DIP-61323N|ensembl:ENSRNOG00000009079(gene)|ensembl:ENSRNOT00000012415(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007612"(learning)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030552"(cAMP binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:1CX4|rcsb pdb:3IDB|rcsb pdb:3IDC|rcsb pdb:4JVA|rcsb pdb:6WJF|rcsb pdb:6WJG|reactome:R-RNO-163615|reactome:R-RNO-164378|reactome:R-RNO-180024|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-432040|reactome:R-RNO-442720|reactome:R-RNO-5610787|reactome:R-RNO-5620912|reactome:R-RNO-8854518|reactome:R-RNO-983231|reactome:R-RNO-2565942|ipi:IPI00365600.3(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:+xQJhnpFwzEnEysPyHpq9x2ZA/g10116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:F1M3G7	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-6096264|uniprotkb:Q8VHU6|ensembl:ENSRNOP00000014802	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:akp13_rat(display_long)|uniprotkb:Akap13(gene name)|psi-mi:Akap13(display_short)|uniprotkb:AKAP-Lbc(gene name synonym)|uniprotkb:Rt13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001099741.2|rgd:727893|ensembl:ENSRNOG00000010964(gene)|ensembl:ENSRNOT00000014802(transcript)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0016020"(membrane)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051168"(nuclear export)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060348"(bone development)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0086023"(adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1900169"(regulation of glucocorticoid mediated signaling pathway)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028852|interpro:IPR035899|interpro:IPR041020|reactome:R-RNO-193648|reactome:R-RNO-416482|reactome:R-RNO-8980692|reactome:R-RNO-9013026|reactome:R-RNO-9013106|ipi:IPI00364348.6(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:/R9ic5TDdVhjEGjxjzklALq788s10116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P09456	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-916215|ensembl:ENSRNOP00000067771	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:kap0_rat(display_long)|uniprotkb:Prkar1a(gene name)|psi-mi:Prkar1a(display_short)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3391|refseq:NP_037313.1|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|reactome:R-RNO-163615|reactome:R-RNO-164378|reactome:R-RNO-180024|reactome:R-RNO-432040|reactome:R-RNO-442720|reactome:R-RNO-5610787|reactome:R-RNO-983231|ensembl:ENSRNOG00000049876(gene)|ensembl:ENSRNOT00000071153(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007507"(heart development)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|refseq:XP_008766533.1|refseq:XP_017452536.1|ipi:IPI00231770.5(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:nGBB094hlb7YlbgO+DYsOaikgjk10116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P15146-4	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-10094313	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:p15146-4(display_long)|uniprotkb:MAP2d(isoform synonym)|uniprotkb:Map2(gene name)|psi-mi:Map2(display_short)|uniprotkb:Mtap2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	intact:EBI-6095638(isoform-parent)|ipi:IPI00231053.1(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:W9qM9PRZmgMZWK9JlDwguf2yTfM10116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P24587	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-6096310|uniprotkb:P70593	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:akap5_rat(display_long)|uniprotkb:Akap5(gene name)|psi-mi:Akap5(display_short)|uniprotkb:Akap150(gene name synonym)|uniprotkb:A-kinase anchor protein 150 kDa(gene name synonym)|uniprotkb:cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR042375|rgd:620829|interpro:IPR001573(Protein kinase A anchoring region)|reactome:R-RNO-399719|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0030425"(dendrite)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036394"(amylase secretion)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043271"(negative regulation of ion transport)|go:"GO:0043624"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045163"(clustering of voltage-gated potassium channels)|go:"GO:0045296"(cadherin binding)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0070073"(clustering of voltage-gated calcium channels)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905751"(positive regulation of endosome to plasma membrane protein transport)|ipi:IPI00215470.2(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:E87Ne3h2sSmpQoa7zXhEowCrXm410116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:O35817	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-6096146|ensembl:ENSRNOP00000009123	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:aka14_rat(display_long)|uniprotkb:Akap14(gene name)|psi-mi:Akap14(display_short)|uniprotkb:Takap80(gene name synonym)|uniprotkb:TAKAP-1.2(gene name synonym)|uniprotkb:Testis-specific A-kinase-anchoring protein TAKAP-80(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:708510|refseq:NP_067735.1|ensembl:ENSRNOG00000006899(gene)|ensembl:ENSRNOT00000009123(transcript)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0051018"(protein kinase A binding)|interpro:IPR025663|ipi:IPI00213019.1(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:GkivdgmMfqU/y1Mp0vJh0IVmE5810116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:Q9Z1C7	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-10094269	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:rpgf4_rat(display_long)|uniprotkb:Rapgef4(gene name)|psi-mi:Rapgef4(display_short)|uniprotkb:Cgef2(gene name synonym)|uniprotkb:Epac2(gene name synonym)|uniprotkb:Exchange factor directly activated by cAMP 2(gene name synonym)|uniprotkb:Exchange protein directly activated by cAMP 2(gene name synonym)|uniprotkb:cAMP-regulated guanine nucleotide exchange factor II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR023578|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR029071|interpro:IPR019804|rgd:621886|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005929"(cilium)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0021510"(spinal cord development)|go:"GO:0030073"(insulin secretion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030552"(cAMP binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044316"(cone cell pedicle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061548"(ganglion development)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1901423"(response to benzene)|go:"GO:1904457"(positive regulation of neuronal action potential)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|reactome:R-RNO-354192|reactome:R-RNO-381676|reactome:R-RNO-392517|reactome:R-RNO-422356|interpro:IPR036964|interpro:IPR008937(Ras guanine nucleotide exchange factor)|ipi:IPI00208697.4(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:Z3V6JSnqvUOzmo3jluC9nytlDeQ10116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P81377	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-6096612	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:kap1_rat(display_long)|uniprotkb:Prkar1b(gene name)|psi-mi:Prkar1b(display_short)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3392|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|reactome:R-RNO-5610787|reactome:R-RNO-983231|interpro:IPR042818|reactome:R-RNO-163615|reactome:R-RNO-164378|reactome:R-RNO-180024|reactome:R-RNO-432040|reactome:R-RNO-442720|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0007611"(learning or memory)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045202"(synapse)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|ipi:IPI00200327.4(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:sVEQr5jZLum1uMRPxzhbpUs0blI10116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P27791	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-917032|uniprotkb:Q6UA68	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:kapca_rat(display_long)|uniprotkb:Prkaca(gene name)|psi-mi:Prkaca(display_short)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3389|mint:P27791|dip:DIP-37312N|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042747"(circadian sleep/wake cycle, REM sleep)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048792"(spontaneous exocytosis of neurotransmitter)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097546"(ciliary base)|go:"GO:0098793"(presynapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|reactome:R-RNO-163615|reactome:R-RNO-164378|reactome:R-RNO-180024|reactome:R-RNO-2565942|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-381676|reactome:R-RNO-392517|reactome:R-RNO-422356|reactome:R-RNO-432040|reactome:R-RNO-4420097|reactome:R-RNO-442720|reactome:R-RNO-512988|reactome:R-RNO-5578775|reactome:R-RNO-5610785|reactome:R-RNO-5610787|reactome:R-RNO-5620912|reactome:R-RNO-5687128|reactome:R-RNO-8853659|reactome:R-RNO-8854518|reactome:R-RNO-8963896|reactome:R-RNO-983231|ipi:IPI00200013.4(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:vfm7xEYQfzaRDobnpGQh57Kpd6Q10116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P12368	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-919521|uniprotkb:Q8K1M2|uniprotkb:G3V8Q6|ensembl:ENSRNOP00000027552	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:kap2_rat(display_long)|uniprotkb:Prkar2a(gene name)|psi-mi:Prkar2a(display_short)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:3393|refseq:NP_062137.1|dip:DIP-555N|ensembl:ENSRNOG00000020284(gene)|ensembl:ENSRNOT00000027552(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0036094"(small molecule binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0097338"(response to clozapine)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:2DRN|rcsb pdb:2H9R|rcsb pdb:2HWN|rcsb pdb:3TMH|reactome:R-RNO-163615|reactome:R-RNO-164378|reactome:R-RNO-180024|reactome:R-RNO-432040|reactome:R-RNO-442720|reactome:R-RNO-5610787|reactome:R-RNO-983231|ipi:IPI00196684.3(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:ZPxd/oQFtg/sxxKaVa+N/yzkUhY10116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:O88884	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-2120138|uniprotkb:O88980	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:akap1_rat(display_long)|uniprotkb:Akap1(gene name)|psi-mi:Akap1(display_short)|uniprotkb:Akap(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 121 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094263|imex:IM-23267-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rgd:620826|refseq:NP_446117.1|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR018459|interpro:IPR002999(Tudor)|interpro:IPR035437|interpro:IPR036612|reactome:R-RNO-983231|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0140374"(antiviral innate immune response)|ipi:IPI00213479.3(identity)	-	-	-	figure legend:Table 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2017/10/20	-	rogid:qj8/sy84ANgre4V1PJECzcHJhus10116	intact-crc:4880D483D9BC09BC	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:17489"	uniprotkb:P00516-2	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-10094470|uniprotkb:P21136-1|ensembl:ENSBTAP00000030518	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:p00516-2(display_long)|uniprotkb:CGK1-beta(isoform synonym)|uniprotkb:PRKG1(gene name)|psi-mi:PRKG1(display_short)|uniprotkb:PRKG1B(gene name synonym)|uniprotkb:PRKGR1A(gene name synonym)|uniprotkb:PRKGR1B(gene name synonym)|uniprotkb:cGMP-dependent protein kinase I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094507|imex:IM-23267-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	intact:EBI-5525781(isoform-parent)|ensembl:ENSBTAG00000018404(gene)|ensembl:ENSBTAT00000030539(transcript)	-	-	-	figure legend:6|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2015/01/22	-	rogid:RqdJyB5eVKkc6LUP/2SOV1a6IXI9913	intact-crc:71340F2E827B18B9	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:17489"	uniprotkb:O35668	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-473704|uniprotkb:O35636|ensembl:ENSMUSP00000133356	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:hap1_mouse(display_long)|uniprotkb:Hap1(gene name)|psi-mi:Hap1(display_short)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094468|imex:IM-23267-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_034534.1|refseq:NP_817090.1|ensembl:ENSMUSG00000006930(gene)|ensembl:ENSMUST00000138603(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008104"(protein localization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016234"(inclusion body)|go:"GO:0017022"(myosin binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021979"(hypothalamus cell differentiation)|go:"GO:0022008"(neurogenesis)|go:"GO:0030426"(growth cone)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032901"(positive regulation of neurotrophin production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048403"(brain-derived neurotrophic factor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|mint:O35668|go:"GO:0030425"(dendrite)|dip:DIP-32510N	-	-	-	figure legend:2, 6|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2015/01/22	-	rogid:mrrVufzrFAAiuT8yarD5JfWlRbc10090	intact-crc:96DFC7B8BDA21D94	false	-	necessary binding region:157-386|mutation disrupting interaction:567-568|red fluorescent protein tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:17489"	uniprotkb:P00516-2	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-10094470|uniprotkb:P21136-1|ensembl:ENSBTAP00000030518	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:p00516-2(display_long)|uniprotkb:CGK1-beta(isoform synonym)|uniprotkb:PRKG1(gene name)|psi-mi:PRKG1(display_short)|uniprotkb:PRKG1B(gene name synonym)|uniprotkb:PRKGR1A(gene name synonym)|uniprotkb:PRKGR1B(gene name synonym)|uniprotkb:cGMP-dependent protein kinase I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094468|imex:IM-23267-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	intact:EBI-5525781(isoform-parent)|ensembl:ENSBTAG00000018404(gene)|ensembl:ENSBTAT00000030539(transcript)	-	-	-	figure legend:2, 6|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2015/01/22	-	rogid:RqdJyB5eVKkc6LUP/2SOV1a6IXI9913	intact-crc:96DFC7B8BDA21D94	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:17489"	uniprotkb:P00516-1	intact:EBI-983884|chebi:"CHEBI:1325"|chebi:"CHEBI:41588"|chebi:"CHEBI:11673"|chebi:"CHEBI:19827"	intact:EBI-10094497|ensembl:ENSBTAP00000024490	psi-mi:3',5'-cyclic amp(display_short)|psi-mi:"CHEBI:17489"(display_long)|intact:3',5'-Cyclic AMP(synonym)|intact:adenosine 3',5'-cyclic monophosphate(synonym)|intact:Adenosine 3',5'-cyclic phosphate(synonym)|intact:Adenosine 3',5'-phosphate(synonym)|intact:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE(synonym)|intact:cAMP(synonym)|intact:Cyclic adenylic acid(synonym)|intact:Cyclic AMP(synonym)|intact:"adenosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:p00516-1(display_long)|uniprotkb:CGK1-alpha(isoform synonym)|uniprotkb:PRKG1(gene name)|psi-mi:PRKG1(display_short)|uniprotkb:PRKG1B(gene name synonym)|uniprotkb:PRKGR1A(gene name synonym)|uniprotkb:PRKGR1B(gene name synonym)|uniprotkb:cGMP-dependent protein kinase I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094492|imex:IM-23267-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	intact:EBI-5525781(isoform-parent)|ensembl:ENSBTAG00000018404(gene)|ensembl:ENSBTAT00000024490(transcript)	-	-	-	figure legend:2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/05	2015/01/22	-	rogid:B9ahkgNZP+yGxincOw5SKBoYaKs9913	intact-crc:7132CF2E827B18B9	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00516-2	uniprotkb:O35668	intact:EBI-10094470|uniprotkb:P21136-1|ensembl:ENSBTAP00000030518	intact:EBI-473704|uniprotkb:O35636|ensembl:ENSMUSP00000133356	psi-mi:p00516-2(display_long)|uniprotkb:CGK1-beta(isoform synonym)|uniprotkb:PRKG1(gene name)|psi-mi:PRKG1(display_short)|uniprotkb:PRKG1B(gene name synonym)|uniprotkb:PRKGR1A(gene name synonym)|uniprotkb:PRKGR1B(gene name synonym)|uniprotkb:cGMP-dependent protein kinase I(gene name synonym)	psi-mi:hap1_mouse(display_long)|uniprotkb:Hap1(gene name)|psi-mi:Hap1(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094520|imex:IM-23267-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5525781(isoform-parent)|ensembl:ENSBTAG00000018404(gene)|ensembl:ENSBTAT00000030539(transcript)	refseq:NP_034534.1|refseq:NP_817090.1|ensembl:ENSMUSG00000006930(gene)|ensembl:ENSMUST00000138603(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008104"(protein localization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016234"(inclusion body)|go:"GO:0017022"(myosin binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021979"(hypothalamus cell differentiation)|go:"GO:0022008"(neurogenesis)|go:"GO:0030426"(growth cone)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032901"(positive regulation of neurotrophin production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048403"(brain-derived neurotrophic factor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|mint:O35668|go:"GO:0030425"(dendrite)|dip:DIP-32510N	-	-	-	figure legend:5|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:13.0x10^-9 ~4.0(molar)	2014/11/05	2015/02/10	rogid:RqdJyB5eVKkc6LUP/2SOV1a6IXI9913	rogid:mrrVufzrFAAiuT8yarD5JfWlRbc10090	intact-crc:B404C74AC347F111|rigid:iTsYeULDwrUEX8Y7rNlyUzk1KB4	false	sufficient binding region:4-55	sufficient binding region:165-189|tetramethyl rhodamine label:n-n	2	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00516-2	uniprotkb:Q9N1F0	intact:EBI-10094470|uniprotkb:P21136-1|ensembl:ENSBTAP00000030518	intact:EBI-10094531|uniprotkb:Q9N1E9	psi-mi:p00516-2(display_long)|uniprotkb:CGK1-beta(isoform synonym)|uniprotkb:PRKG1(gene name)|psi-mi:PRKG1(display_short)|uniprotkb:PRKG1B(gene name synonym)|uniprotkb:PRKGR1A(gene name synonym)|uniprotkb:PRKGR1B(gene name synonym)|uniprotkb:cGMP-dependent protein kinase I(gene name synonym)	psi-mi:irag1_bovin(display_long)|uniprotkb:IRAG1(gene name)|psi-mi:IRAG1(display_short)|uniprotkb:IRAG(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate(gene name synonym)|uniprotkb:JAW1-related protein MRVI1(gene name synonym)|uniprotkb:MRVI1(gene name synonym)|uniprotkb:Protein MRVI1(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Corradini et al. (2015)	pubmed:25653285|imex:IM-23267	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10094529|imex:IM-23267-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5525781(isoform-parent)|ensembl:ENSBTAG00000018404(gene)|ensembl:ENSBTAT00000030539(transcript)	interpro:IPR008677(MRVI1)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)	-	-	-	figure legend:5|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:26.0x10^-9 ~6.0(molar)	2014/11/05	2015/02/10	rogid:RqdJyB5eVKkc6LUP/2SOV1a6IXI9913	rogid:kB20yHt9P/PD76rl5pm/zX5+meU9913	intact-crc:253CFA129F438847|rigid:k4dLxvxKecGwMGy9fmm83KyZZs8	false	sufficient binding region:4-55	tetramethyl rhodamine label:n-n|sufficient binding region:556-580	2	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)