#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P62805 uniprotkb:P55201 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820115|imex:IM-23182-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N go:4QYD - - figure legend:t1 f2b f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/09/18 2014/10/16 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 intact-crc:CFD7CAC2D06BACF0|rigid:nVkYhdoP/BD509lDLxmkqo5ja6s false N-acetylated L-lysine:12-12|binding-associated region:4-17 binding-associated region:629-742 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C0S8 uniprotkb:P55201 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820185|imex:IM-23182-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N go:4QYL - - figure legend:T1 f1c f1d f2a f2c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/09/18 2014/10/16 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 intact-crc:810E7D0EF6D954F1|rigid:uQRpuPxIH/gT0t5UgL9afu4jvKI false N-acetylated L-lysine:5-5|binding-associated region:1-12 binding-associated region:629-742 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62805 uniprotkb:P55201 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820527|imex:IM-23182-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N - - - figure legend:f3b f3c sf2g sf3g|comment:"No binding was observed between BRPF1 and H4(4-17) unmodified peptide."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:108.5x10^-6(molar) 2014/09/18 2014/10/16 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 intact-crc:6EA9D21EE8882E06|rigid:nVkYhdoP/BD509lDLxmkqo5ja6s false N-acetylated L-lysine:12-12|binding-associated region:4-17 binding-associated region:629-742|mutation decreasing interaction:709-709 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62805 uniprotkb:P55201 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820557|imex:IM-23182-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N - - - figure legend:f3b f3c sf2f sf3f|comment:"No binding was observed between BRPF1 and H4(4-17) unmodified peptide."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:471.6x10^-6(molar) 2014/09/18 2014/10/16 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 intact-crc:563F2FA0E3B1734F|rigid:nVkYhdoP/BD509lDLxmkqo5ja6s false binding-associated region:4-17|N-acetylated L-lysine:12-12 mutation decreasing interaction:713-713|binding-associated region:629-742 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55201 uniprotkb:P62805 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820542|imex:IM-23182-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:f3b f3c sf2d sf3d|comment:"No binding was observed between BRPF1 and H4(4-17) unmodified peptide."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:205.6x10^-6(molar) 2014/09/18 2014/10/16 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:0B6C1C19D89AC662|rigid:nVkYhdoP/BD509lDLxmkqo5ja6s false mutation decreasing interaction:661-661|binding-associated region:629-742 N-acetylated L-lysine:12-12|binding-associated region:4-17 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55201 uniprotkb:P62805 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820642|imex:IM-23182-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:f3b f3c sf2b sf3b|comment:"No binding was observed between BRPF1 and H4(4-17) unmodified peptide."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/09/18 2014/10/16 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:AF2829417DA5181D|rigid:nVkYhdoP/BD509lDLxmkqo5ja6s false mutation disrupting interaction:708-708|binding-associated region:629-742 N-acetylated L-lysine:12-12|binding-associated region:4-17 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C0S8 uniprotkb:P55201 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820492|imex:IM-23182-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N - - - figure legend:f3a sf1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/09/18 2014/10/16 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 intact-crc:F9CE338353E55E98|rigid:uQRpuPxIH/gT0t5UgL9afu4jvKI false binding-associated region:1-12|N-acetylated L-lysine:5-5 binding-associated region:629-742|mutation disrupting interaction:708-708 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62805 uniprotkb:P55201 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820507|imex:IM-23182-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N - - - figure legend:f3b f3c sf2a sf3a|comment:"No binding was observed between BRPF1 and H4(4-17) unmodified peptide."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:89.5x10^-6(molar) 2014/09/18 2014/10/16 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 intact-crc:6C7830EAF0F75444|rigid:nVkYhdoP/BD509lDLxmkqo5ja6s false binding-associated region:4-17|N-acetylated L-lysine:12-12 binding-associated region:629-742 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55201 uniprotkb:P0C0S8 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820365|imex:IM-23182-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:f3a sf1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:77.5x10^-6(molar) 2014/09/18 2014/10/16 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:BE8CDC0D10110AF0|rigid:uQRpuPxIH/gT0t5UgL9afu4jvKI false mutation decreasing interaction:661-661|binding-associated region:629-742 N-acetylated L-lysine:5-5|binding-associated region:1-12 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C0S8 uniprotkb:P55201 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820343|imex:IM-23182-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N - - - figure legend:f3a sf1g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:59.6x10^-6(molar) 2014/09/18 2014/10/16 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 intact-crc:3D944C6089ECC077|rigid:uQRpuPxIH/gT0t5UgL9afu4jvKI false N-acetylated L-lysine:5-5|binding-associated region:1-12 binding-associated region:629-742|mutation decreasing interaction:709-709 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55201 uniprotkb:P0C0S8 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820282|imex:IM-23182-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:f3a sf1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:48.5x10^-6(molar) 2014/09/18 2014/10/16 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:D79F67376538FA2B|rigid:uQRpuPxIH/gT0t5UgL9afu4jvKI false binding-associated region:629-742 N-acetylated L-lysine:5-5|binding-associated region:1-12 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C0S8 uniprotkb:P55201 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820402|imex:IM-23182-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N - - - figure legend:f3a sf1e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:124.2x10^-6(molar) 2014/09/18 2014/10/16 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 intact-crc:BF5C42B3E82F38DF|rigid:uQRpuPxIH/gT0t5UgL9afu4jvKI false N-acetylated L-lysine:5-5|binding-associated region:1-12 binding-associated region:629-742|mutation decreasing interaction:704-704 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55201 uniprotkb:P62805 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820572|imex:IM-23182-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:f3b f3c sf2e sf3e|comment:"No binding was observed between BRPF1 and H4(4-17) unmodified peptide."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:470.47x10^-6(molar) 2014/09/18 2014/10/16 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:15D4E65E8F824369|rigid:nVkYhdoP/BD509lDLxmkqo5ja6s false binding-associated region:629-742|mutation decreasing interaction:704-704 N-acetylated L-lysine:12-12|binding-associated region:4-17 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55201 uniprotkb:P0C0S8 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820387|imex:IM-23182-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:f3a sf1f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:119.9x10^-6(molar) 2014/09/18 2014/10/16 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:64F01485A75DFE92|rigid:uQRpuPxIH/gT0t5UgL9afu4jvKI false binding-associated region:629-742|mutation decreasing interaction:713-713 binding-associated region:1-12|N-acetylated L-lysine:5-5 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55201 uniprotkb:P0C0S8 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820476|imex:IM-23182-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:f3a sf1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/09/18 2014/10/16 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:D901DE51353DB8B9|rigid:uQRpuPxIH/gT0t5UgL9afu4jvKI false binding-associated region:629-742|mutation disrupting interaction:714-714 binding-associated region:1-12|N-acetylated L-lysine:5-5 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62805 uniprotkb:P55201 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lubula et al. (2014) pubmed:25281266|imex:IM-23182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9820587|imex:IM-23182-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N - - - figure legend:f3b f3c sf2c sf3c|comment:"No binding was observed between BRPF1 and H4(4-17) unmodified peptide."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/09/18 2014/10/16 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 intact-crc:77BBC9157A1471AB|rigid:nVkYhdoP/BD509lDLxmkqo5ja6s false binding-associated region:4-17|N-acetylated L-lysine:12-12 binding-associated region:629-742|mutation disrupting interaction:714-714 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)