#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9HCN4 uniprotkb:Q9UHW5 intact:EBI-745137|uniprotkb:O76004|uniprotkb:B4DQJ5|uniprotkb:B4DXU4|uniprotkb:B4DQM4|ensembl:ENSP00000476446|uniprotkb:B5MBZ5 intact:EBI-395491|uniprotkb:Q53FS3|uniprotkb:Q6UVZ6|uniprotkb:Q7Z3D3|uniprotkb:Q8NEI2|uniprotkb:Q96HK9|uniprotkb:B2RC54|uniprotkb:D4YWV1|ensembl:ENSP00000228827|uniprotkb:F5H759 psi-mi:gpn1_human(display_long)|uniprotkb:XAB1(gene name synonym)|uniprotkb:XPA-binding protein 1(gene name synonym)|uniprotkb:MBD2-interacting protein(gene name synonym)|uniprotkb:GPN1(gene name)|psi-mi:GPN1(display_short)|uniprotkb:MBDIN(gene name synonym)|uniprotkb:HUSSY-23(orf name)|uniprotkb:RNAPII-associated protein 4(gene name synonym)|uniprotkb:RPAP4(gene name synonym) psi-mi:gpn3_human(display_long)|uniprotkb:ATPBD1C(gene name synonym)|uniprotkb:ATP-binding domain 1 family member C(gene name synonym)|uniprotkb:GPN3(gene name)|psi-mi:GPN3(display_short)|uniprotkb:AD-009(orf name)|uniprotkb:UNQ1876/PRO4319(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Méndez-Hernández et al. (2014) imex:IM-23174|pubmed:25241168 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9696505|imex:IM-23174-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138519.1|refseq:NP_001138520.1|refseq:NP_001138521.1|refseq:NP_009197.2|ensembl:ENSG00000198522(gene)|ensembl:ENST00000610189(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030230|mint:Q9HCN4 refseq:NP_001157844.1|refseq:NP_001157845.1|refseq:NP_057385.3|ensembl:ENSG00000111231(gene)|ensembl:ENST00000228827(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|mint:Q9UHW5 go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus) - - figure legend:f3a|comment:"Gpn3-EYFP coexpressed with Gpn1-Flag displayed a cytoplasmic localization for the 24h that lasted this experiment, in contrast with the nuclear localization of Gpn3-EYFP when expressed alone (Fig 1A), which suggests that Gpn3-EYFP remained associated with Gpn1-Flag at all times (see Fig 4). More importantly, these results indicate that the mobilization of Gpn3-EYFP and Gpn1-Flag into the cell nucleus observed in the presence of LMB very likely occurs as a Gpn3-EYFP/Gpn1-Flag single protein complex. At the single cell level the nuclear accumulation of Gpn3- EYFP in the presence of LMB was always associated with nuclear Gpn1-Flag (Fig. 3A), supporting the proposal that the mobilization of Gpn3-EYFP and Gpn1-Flag occurs as a single complex."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/08/28 2014/10/16 rogid:QZOTFh9d1hOcoG1DxAueYEwbOpc9606 rogid:fKBsnLcvitaM76zQUW+MQXDPxTA9606 intact-crc:1677CED7508946D7|rigid:acejlrhbkaZQt9JWaOdbvU0lUkU false flag tag:?-? yellow fluorescent protein tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9UHW5 uniprotkb:Q9HCN4 intact:EBI-395491|uniprotkb:Q53FS3|uniprotkb:Q6UVZ6|uniprotkb:Q7Z3D3|uniprotkb:Q8NEI2|uniprotkb:Q96HK9|uniprotkb:B2RC54|uniprotkb:D4YWV1|ensembl:ENSP00000228827|uniprotkb:F5H759 intact:EBI-745137|uniprotkb:O76004|uniprotkb:B4DQJ5|uniprotkb:B4DXU4|uniprotkb:B4DQM4|ensembl:ENSP00000476446|uniprotkb:B5MBZ5 psi-mi:gpn3_human(display_long)|uniprotkb:ATPBD1C(gene name synonym)|uniprotkb:ATP-binding domain 1 family member C(gene name synonym)|uniprotkb:GPN3(gene name)|psi-mi:GPN3(display_short)|uniprotkb:AD-009(orf name)|uniprotkb:UNQ1876/PRO4319(orf name) psi-mi:gpn1_human(display_long)|uniprotkb:XAB1(gene name synonym)|uniprotkb:XPA-binding protein 1(gene name synonym)|uniprotkb:MBD2-interacting protein(gene name synonym)|uniprotkb:GPN1(gene name)|psi-mi:GPN1(display_short)|uniprotkb:MBDIN(gene name synonym)|uniprotkb:HUSSY-23(orf name)|uniprotkb:RNAPII-associated protein 4(gene name synonym)|uniprotkb:RPAP4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Méndez-Hernández et al. (2014) imex:IM-23174|pubmed:25241168 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9695534|imex:IM-23174-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157844.1|refseq:NP_001157845.1|refseq:NP_057385.3|ensembl:ENSG00000111231(gene)|ensembl:ENST00000228827(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|mint:Q9UHW5 refseq:NP_001138519.1|refseq:NP_001138520.1|refseq:NP_001138521.1|refseq:NP_009197.2|ensembl:ENSG00000198522(gene)|ensembl:ENST00000610189(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030230|mint:Q9HCN4 - - - figure legend:f4b|comment:"Gpn3-EYFP coexpressed with Gpn1-Flag displayed a cytoplasmic localization for the 24h that lasted this experiment, in contrast with the nuclear localization of Gpn3-EYFP when expressed alone (Fig 1A), which suggests that Gpn3-EYFP remained associated with Gpn1-Flag at all times (see Fig 4). More importantly, these results indicate that the mobilization of Gpn3-EYFP and Gpn1-Flag into the cell nucleus observed in the presence of LMB very likely occurs as a Gpn3-EYFP/Gpn1-Flag single protein complex. At the single cell level the nuclear accumulation of Gpn3- EYFP in the presence of LMB was always associated with nuclear Gpn1-Flag (Fig. 3A), supporting the proposal that the mobilization of Gpn3-EYFP and Gpn1-Flag occurs as a single complex."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/08/28 2014/10/16 rogid:fKBsnLcvitaM76zQUW+MQXDPxTA9606 rogid:QZOTFh9d1hOcoG1DxAueYEwbOpc9606 intact-crc:628C37813EF9E8AC|rigid:acejlrhbkaZQt9JWaOdbvU0lUkU false yellow fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9HCN4 uniprotkb:Q9UHW5 intact:EBI-745137|uniprotkb:O76004|uniprotkb:B4DQJ5|uniprotkb:B4DXU4|uniprotkb:B4DQM4|ensembl:ENSP00000476446|uniprotkb:B5MBZ5 intact:EBI-395491|uniprotkb:Q53FS3|uniprotkb:Q6UVZ6|uniprotkb:Q7Z3D3|uniprotkb:Q8NEI2|uniprotkb:Q96HK9|uniprotkb:B2RC54|uniprotkb:D4YWV1|ensembl:ENSP00000228827|uniprotkb:F5H759 psi-mi:gpn1_human(display_long)|uniprotkb:XAB1(gene name synonym)|uniprotkb:XPA-binding protein 1(gene name synonym)|uniprotkb:MBD2-interacting protein(gene name synonym)|uniprotkb:GPN1(gene name)|psi-mi:GPN1(display_short)|uniprotkb:MBDIN(gene name synonym)|uniprotkb:HUSSY-23(orf name)|uniprotkb:RNAPII-associated protein 4(gene name synonym)|uniprotkb:RPAP4(gene name synonym) psi-mi:gpn3_human(display_long)|uniprotkb:ATPBD1C(gene name synonym)|uniprotkb:ATP-binding domain 1 family member C(gene name synonym)|uniprotkb:GPN3(gene name)|psi-mi:GPN3(display_short)|uniprotkb:AD-009(orf name)|uniprotkb:UNQ1876/PRO4319(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Méndez-Hernández et al. (2014) imex:IM-23174|pubmed:25241168 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9694923|imex:IM-23174-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138519.1|refseq:NP_001138520.1|refseq:NP_001138521.1|refseq:NP_009197.2|ensembl:ENSG00000198522(gene)|ensembl:ENST00000610189(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030230|mint:Q9HCN4 refseq:NP_001157844.1|refseq:NP_001157845.1|refseq:NP_057385.3|ensembl:ENSG00000111231(gene)|ensembl:ENST00000228827(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|mint:Q9UHW5 - - - figure legend:f4a|comment:"Gpn3-EYFP coexpressed with Gpn1-Flag displayed a cytoplasmic localization for the 24h that lasted this experiment, in contrast with the nuclear localization of Gpn3-EYFP when expressed alone (Fig 1A), which suggests that Gpn3-EYFP remained associated with Gpn1-Flag at all times (see Fig 4). More importantly, these results indicate that the mobilization of Gpn3-EYFP and Gpn1-Flag into the cell nucleus observed in the presence of LMB very likely occurs as a Gpn3-EYFP/Gpn1-Flag single protein complex. At the single cell level the nuclear accumulation of Gpn3- EYFP in the presence of LMB was always associated with nuclear Gpn1-Flag (Fig. 3A), supporting the proposal that the mobilization of Gpn3-EYFP and Gpn1-Flag occurs as a single complex."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/08/28 2014/10/16 rogid:QZOTFh9d1hOcoG1DxAueYEwbOpc9606 rogid:fKBsnLcvitaM76zQUW+MQXDPxTA9606 intact-crc:1B27AAF54A9DD6C8|rigid:acejlrhbkaZQt9JWaOdbvU0lUkU false yellow fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)