#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q08412	uniprotkb:P38182	intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym)	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9873900|imex:IM-23241-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	-	crc64:0D455F9AD637AC8D	crc64:1246CEFF5A038819	figure legend:Fig. 2E|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/10/27	2014/11/25	rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	intact-crc:4C93E5F1673CC125|rigid:f22pww0WPz7CN+nyanQv0uH5sXY	false	mutation decreasing interaction strength:373-373|mutation decreasing interaction strength:376-376|glutathione s tranferase tag:?-?|mutation disrupting interaction strength:373-376	his tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H0E2	uniprotkb:P38182	intact:EBI-74615|ensembl:ENSP00000314733|uniprotkb:Q9H9E6|uniprotkb:Q9UJ69|uniprotkb:B3KXC6	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	psi-mi:tolip_human(display_long)|uniprotkb:TOLLIP(gene name)|psi-mi:TOLLIP(display_short)	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9991009|imex:IM-23241-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078902(gene)|ensembl:ENST00000317204(transcript)|go:"GO:0005150"(interleukin-1, type I receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0016310"(phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045321"(leukocyte activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR035892|interpro:IPR037301|interpro:IPR041799|rcsb pdb:1WGL|rcsb pdb:2N31|reactome:R-HSA-6798695|reactome:R-HSA-9020702|refseq:NP_061882.2|refseq:NP_001305441.1|refseq:NP_001305443.1|refseq:NP_001305444.1|refseq:NP_001305445.1|dip:DIP-30845N	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	-	-	crc64:1246CEFF5A038819	figure legend:Supp. Fig. 6G|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/10/27	2014/12/04	rogid:HR6/CGVYMtuDqxW44fBD/KjScnk9606	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	intact-crc:5C79B64335CFBF67|rigid:XAg6u5W7VnBAgS26DjbzL2vuQ7s	false	green fluorescent protein tag:?-?	ha tag:n-n|protein modification:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q08412	uniprotkb:P38182	intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym)	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9873849|imex:IM-23241-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	-	crc64:0D455F9AD637AC8D	crc64:1246CEFF5A038819	figure legend:Fig. 2C|agonist:Starvation|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/10/27	2014/10/27	rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	intact-crc:2A912707544A54F6|rigid:f22pww0WPz7CN+nyanQv0uH5sXY	false	myc tag:c-c	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q08412	uniprotkb:P35691	intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W	intact:EBI-19081|uniprotkb:D6VXN1|ensemblfungi:YKL056C	psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym)	psi-mi:tctp_yeast(display_long)|uniprotkb:MMI1(gene name synonym)|uniprotkb:YKL056C(locus name)|uniprotkb:YKL312(orf name)|uniprotkb:TMA19(gene name)|psi-mi:TMA19(display_short)|uniprotkb:Translation machinery-associated protein 19(gene name synonym)|uniprotkb:Microtubule and mitochondria-interacting protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9875699|imex:IM-23241-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695	refseq:NP_012867.1|sgd:S000001539|ensemblfungi:YKL056C(gene)|ensemblfungi:YKL056C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR011057(Mss4-like)|interpro:IPR011323(Mss4/translationally controlled tumour-associated TCTP)|interpro:IPR018103|go:"GO:0007026"(negative regulation of microtubule depolymerization)|interpro:IPR018105|interpro:IPR034737|dip:DIP-2116N|mint:P35691	-	crc64:0D455F9AD637AC8D	crc64:C4407A3B3B77124A	figure legend:Fig. 4D|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/10/27	2014/11/25	rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292	rogid:ogLF9Xtzsu9YLiBRgpmC83FNthY559292	intact-crc:17B7A8B5D54E8C4C|rigid:a3jspDF7wFz4utB5h0o/L2xVxbo	false	myc tag:c-c	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q08412	uniprotkb:P39940	intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W	intact:EBI-16219|ensemblfungi:YER125W|uniprotkb:D3DM31	psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym)	psi-mi:rsp5_yeast(display_long)|uniprotkb:RSP5(gene name)|psi-mi:RSP5(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:NPI1(gene name synonym)|uniprotkb:YER125W(locus name)|uniprotkb:SYGP-ORF41(orf name)|uniprotkb:Reverses SPT-phenotype protein 5(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase RSP5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9875699|imex:IM-23241-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695	ensemblfungi:YER125W(gene)|ensemblfungi:YER125W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010794"(regulation of dolichol biosynthetic process)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0019220"(regulation of phosphate metabolic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034517"(ribophagy)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042493"|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:2000203"(regulation of ribosomal large subunit export from nucleus)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000235"(regulation of tRNA processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:2000238"(regulation of tRNA export from nucleus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:3OLM|rcsb pdb:4LCD|rcsb pdb:5HPL|reactome:R-SCE-1169408|reactome:R-SCE-8948751|reactome:R-SCE-9013406|reactome:R-SCE-983168|sgd:S000000927|refseq:NP_011051.3|dip:DIP-2238N|mint:P39940	-	crc64:0D455F9AD637AC8D	crc64:6F1836384479E70F	figure legend:Fig. 4D|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/10/27	2014/11/25	rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292	rogid:IoFCQz3aNFApg/LSyc6Si4dsDc0559292	intact-crc:17B7A8B5D54E8C4C|rigid:a3jspDF7wFz4utB5h0o/L2xVxbo	false	myc tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q08412	uniprotkb:P39940	intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W	intact:EBI-16219|ensemblfungi:YER125W|uniprotkb:D3DM31	psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym)	psi-mi:rsp5_yeast(display_long)|uniprotkb:RSP5(gene name)|psi-mi:RSP5(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:NPI1(gene name synonym)|uniprotkb:YER125W(locus name)|uniprotkb:SYGP-ORF41(orf name)|uniprotkb:Reverses SPT-phenotype protein 5(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase RSP5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9875730|imex:IM-23241-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695	ensemblfungi:YER125W(gene)|ensemblfungi:YER125W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010794"(regulation of dolichol biosynthetic process)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0019220"(regulation of phosphate metabolic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034517"(ribophagy)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042493"|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:2000203"(regulation of ribosomal large subunit export from nucleus)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000235"(regulation of tRNA processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:2000238"(regulation of tRNA export from nucleus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:3OLM|rcsb pdb:4LCD|rcsb pdb:5HPL|reactome:R-SCE-1169408|reactome:R-SCE-8948751|reactome:R-SCE-9013406|reactome:R-SCE-983168|sgd:S000000927|refseq:NP_011051.3|dip:DIP-2238N|mint:P39940	-	crc64:0D455F9AD637AC8D	crc64:6F1836384479E70F	figure legend:Fig. 4D|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/10/27	2014/11/25	rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292	rogid:IoFCQz3aNFApg/LSyc6Si4dsDc0559292	intact-crc:68C06805A8953C1D|rigid:OKtdOp099vKIKOQ4+9+Z2tb+wwA	false	myc tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q08412	uniprotkb:P20081	intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym)	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9875730|imex:IM-23241-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT	-	crc64:0D455F9AD637AC8D	crc64:65C134830D300C06	figure legend:Fig. 4D|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/10/27	2014/11/25	rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	intact-crc:68C06805A8953C1D|rigid:OKtdOp099vKIKOQ4+9+Z2tb+wwA	false	myc tag:c-c	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38182	uniprotkb:Q08412	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9873858|imex:IM-23241-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695	-	crc64:1246CEFF5A038819	crc64:0D455F9AD637AC8D	figure legend:Fig. 2D|agonist:Starvation|comment:Cue5 preferentially interacts with the lipidated form of Atg8|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/10/27	2014/10/27	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292	intact-crc:C269F4CFA36E5E52|rigid:f22pww0WPz7CN+nyanQv0uH5sXY	false	ha tag:n-n|protein modification:?-?	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P39940	uniprotkb:Q08412	intact:EBI-16219|ensemblfungi:YER125W|uniprotkb:D3DM31	intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W	psi-mi:rsp5_yeast(display_long)|uniprotkb:RSP5(gene name)|psi-mi:RSP5(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:NPI1(gene name synonym)|uniprotkb:YER125W(locus name)|uniprotkb:SYGP-ORF41(orf name)|uniprotkb:Reverses SPT-phenotype protein 5(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase RSP5(gene name synonym)	psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9875741|imex:IM-23241-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER125W(gene)|ensemblfungi:YER125W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010794"(regulation of dolichol biosynthetic process)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0019220"(regulation of phosphate metabolic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034517"(ribophagy)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042493"|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:2000203"(regulation of ribosomal large subunit export from nucleus)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000235"(regulation of tRNA processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:2000238"(regulation of tRNA export from nucleus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:3OLM|rcsb pdb:4LCD|rcsb pdb:5HPL|reactome:R-SCE-1169408|reactome:R-SCE-8948751|reactome:R-SCE-9013406|reactome:R-SCE-983168|sgd:S000000927|refseq:NP_011051.3|dip:DIP-2238N|mint:P39940	refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695	-	crc64:6F1836384479E70F	crc64:0D455F9AD637AC8D	figure legend:Fig. 4E|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/10/27	2014/11/25	rogid:IoFCQz3aNFApg/LSyc6Si4dsDc0559292	rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292	intact-crc:A1B7C87D30A5260E|rigid:e7geWPmLBeXENEuZiUhF9K5Wr6w	false	ha tag:n-n	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38182	uniprotkb:P40344	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-3381|uniprotkb:D6W1I2|ensemblfungi:YNR007C	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:atg3_yeast(display_long)|uniprotkb:Autophagy-related E2-like conjugation enzyme ATG3(gene name synonym)|uniprotkb:ATG3(gene name)|psi-mi:ATG3(display_short)|uniprotkb:AUT1(gene name synonym)|uniprotkb:YNR007C(locus name)|uniprotkb:N2040(orf name)|uniprotkb:APG3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9875548|imex:IM-23241-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	sgd:S000005290|refseq:NP_014404.3|dip:DIP-1190N|mint:P40344|ensemblfungi:YNR007C(gene)|ensemblfungi:YNR007C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000153"(cytoplasmic ubiquitin ligase complex)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0019776"(Atg8 ligase activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061908"(phagophore)|interpro:IPR007135(Autophagocytosis associated protein, C-terminal)|rcsb pdb:2DYT|rcsb pdb:3T7G|rcsb pdb:4GSL|rcsb pdb:6OJJ|reactome:R-SCE-1632852	-	crc64:1246CEFF5A038819	crc64:52CCFB216B18CF0C	figure legend:Supp. Fig. 2A, 2B|agonist:Starvation|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/10/27	2014/10/30	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:LLgDB7xi+ynGqu140MvZGSaAAXM559292	intact-crc:26987988E4B55C57|rigid:ZfYb6wVe8yEb0+oMNWA0t0UtCM8	false	ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38182	uniprotkb:P38862	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-2677|uniprotkb:D3DLC0|ensemblfungi:YHR171W	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:atg7_yeast(display_long)|uniprotkb:ATG7(gene name)|psi-mi:ATG7(display_short)|uniprotkb:APG7(gene name synonym)|uniprotkb:CVT2(gene name synonym)|uniprotkb:ATG12-activating enzyme E1 ATG7(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 2(gene name synonym)|uniprotkb:Autophagy-related protein 7(gene name synonym)|uniprotkb:YHR171W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9875548|imex:IM-23241-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	sgd:S000001214|refseq:NP_012041.1|reactome:R-SCE-1632852|reactome:R-SCE-6798695|dip:DIP-1196N|ensemblfungi:YHR171W(gene)|ensemblfungi:YHR171W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019778"(Atg12 activating enzyme activity)|go:"GO:0019779"(Atg8 activating enzyme activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR006285(E1-like protein-activating enzyme Gsa7p/Apg7p)|interpro:IPR032197|interpro:IPR035985|interpro:IPR042522|interpro:IPR042523|rcsb pdb:2LI5|rcsb pdb:3RUI|rcsb pdb:3RUJ|rcsb pdb:3T7E|rcsb pdb:3T7F|rcsb pdb:3T7G|rcsb pdb:3T7H|rcsb pdb:3VH1|rcsb pdb:3VH2|reactome:R-SCE-983168|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:4GSJ|rcsb pdb:4GSK|rcsb pdb:4GSL|rcsb pdb:5YEC	-	crc64:1246CEFF5A038819	crc64:561EEC94F0ED57F5	figure legend:Supp. Fig. 2A, 2B|agonist:Starvation|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/10/27	2014/10/30	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:d9sYZJRVHd00XhEjw0xjYrlL0NE559292	intact-crc:26987988E4B55C57|rigid:ZfYb6wVe8yEb0+oMNWA0t0UtCM8	false	ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38182	uniprotkb:Q08412	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9875548|imex:IM-23241-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695	-	crc64:1246CEFF5A038819	crc64:0D455F9AD637AC8D	figure legend:Supp. Fig. 2A, 2B|agonist:Starvation|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/10/27	2014/10/30	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292	intact-crc:26987988E4B55C57|rigid:ZfYb6wVe8yEb0+oMNWA0t0UtCM8	false	ha tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P42858	uniprotkb:P38182	intact:EBI-466029|uniprotkb:Q9UQB7|ensembl:ENSP00000347184	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	psi-mi:hd_human(display_long)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym)	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9875786|imex:IM-23241-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000197386(gene)|refseq:NP_002102.4|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|rcsb pdb:6EZ8|rcsb pdb:6N8C|rcsb pdb:6RMH|rcsb pdb:6X9O|rcsb pdb:6YEJ|rcsb pdb:7DXJ|rcsb pdb:7DXK|reactome:R-HSA-9022692|ensembl:ENST00000355072(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0016234"(inclusion body)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034452"(dynactin binding)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000091(Huntingtin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|interpro:IPR024613|interpro:IPR028426|mint:P42858|rcsb pdb:2D3X|rcsb pdb:2LD0|rcsb pdb:2LD2|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|dip:DIP-32492N	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	-	-	crc64:1246CEFF5A038819	figure legend:Fig. 5D|comment:Atg8 does not bind the none-aggregation-prone Htt-20Q protein variant.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/10/27	2014/10/30	rogid:KyttHE2o2fORsw6iTh94LB7QShA9606	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	intact-crc:168D236CF1C79054|rigid:Oc25DTNRi421dB0pFEpbSm7sfAM	false	variant:18-18	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P42858	uniprotkb:Q08412	intact:EBI-466029|uniprotkb:Q9UQB7|ensembl:ENSP00000347184	intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W	psi-mi:hd_human(display_long)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym)	psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9875795|imex:IM-23241-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000197386(gene)|refseq:NP_002102.4|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|rcsb pdb:6EZ8|rcsb pdb:6N8C|rcsb pdb:6RMH|rcsb pdb:6X9O|rcsb pdb:6YEJ|rcsb pdb:7DXJ|rcsb pdb:7DXK|reactome:R-HSA-9022692|ensembl:ENST00000355072(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0016234"(inclusion body)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034452"(dynactin binding)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000091(Huntingtin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|interpro:IPR024613|interpro:IPR028426|mint:P42858|rcsb pdb:2D3X|rcsb pdb:2LD0|rcsb pdb:2LD2|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|dip:DIP-32492N	refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695	-	-	crc64:0D455F9AD637AC8D	figure legend:Fig. 5D, 5E|comment:Cue5 does not bind the none-aggregation-prone Htt-20Q protein variant.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/10/27	2014/10/30	rogid:KyttHE2o2fORsw6iTh94LB7QShA9606	rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292	intact-crc:2E43B038C9E0FEDA|rigid:W+/HwpOER+O4Teb6oNdTGY2vTGk	false	variant:18-18	ha tag:c-c|mutation disrupting interaction strength:135-136	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H492	uniprotkb:Q9H0E2	intact:EBI-720768|intact:EBI-28977435|ensembl:ENSP00000353886|ensembl:ENSP00000380821|uniprotkb:Q9BXW5|uniprotkb:E1P5P4|uniprotkb:E1P5P5	intact:EBI-74615|ensembl:ENSP00000314733|uniprotkb:Q9H9E6|uniprotkb:Q9UJ69|uniprotkb:B3KXC6	psi-mi:mlp3a_human(display_long)|uniprotkb:Microtubule-associated protein 1 light chain 3 alpha(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 A(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 1(gene name synonym)|uniprotkb:Autophagy-related protein LC3 A(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 A(gene name synonym)|uniprotkb:MAP1LC3A(gene name)|psi-mi:MAP1LC3A(display_short)	psi-mi:tolip_human(display_long)|uniprotkb:TOLLIP(gene name)|psi-mi:TOLLIP(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9975845|imex:IM-23241-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101460(gene)|ensembl:ENST00000360668(transcript)|ensembl:ENST00000397709(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043278"(response to morphine)|go:"GO:0044754"(autolysosome)|go:"GO:0045202"(synapse)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q9H492|rcsb pdb:3ECI|rcsb pdb:3WAL|rcsb pdb:3WAN|rcsb pdb:4ZDV|rcsb pdb:5CX3|rcsb pdb:5DPR|rcsb pdb:6TBE|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8934903|refseq:NP_115903.1|refseq:NP_852610.1|ensembl:ENSP00000353886|ensembl:ENST00000374837|ensembl:ENSP00000363970|ensembl:ENSP00000380821|dip:DIP-49052N	ensembl:ENSG00000078902(gene)|ensembl:ENST00000317204(transcript)|go:"GO:0005150"(interleukin-1, type I receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0016310"(phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045321"(leukocyte activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR035892|interpro:IPR037301|interpro:IPR041799|rcsb pdb:1WGL|rcsb pdb:2N31|reactome:R-HSA-6798695|reactome:R-HSA-9020702|refseq:NP_061882.2|refseq:NP_001305441.1|refseq:NP_001305443.1|refseq:NP_001305444.1|refseq:NP_001305445.1|dip:DIP-30845N	go:"GO:0005776"(autophagosome)	-	-	figure legend:Fig. 6D|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/27	2014/11/25	rogid:qtZ3YM26FhxTs/gW+KFMllsVhn49606	rogid:HR6/CGVYMtuDqxW44fBD/KjScnk9606	intact-crc:5A362641B2F9F7F1|rigid:9QgiPdI247C5M0/JdJhUxeEiMIg	false	green fluorescent protein tag:n-n	red fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9H0E2	uniprotkb:Q9H492	intact:EBI-74615|ensembl:ENSP00000314733|uniprotkb:Q9H9E6|uniprotkb:Q9UJ69|uniprotkb:B3KXC6	intact:EBI-720768|intact:EBI-28977435|ensembl:ENSP00000353886|ensembl:ENSP00000380821|uniprotkb:Q9BXW5|uniprotkb:E1P5P4|uniprotkb:E1P5P5	psi-mi:tolip_human(display_long)|uniprotkb:TOLLIP(gene name)|psi-mi:TOLLIP(display_short)	psi-mi:mlp3a_human(display_long)|uniprotkb:Microtubule-associated protein 1 light chain 3 alpha(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 A(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 1(gene name synonym)|uniprotkb:Autophagy-related protein LC3 A(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 A(gene name synonym)|uniprotkb:MAP1LC3A(gene name)|psi-mi:MAP1LC3A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9975868|imex:IM-23241-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078902(gene)|ensembl:ENST00000317204(transcript)|go:"GO:0005150"(interleukin-1, type I receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0016310"(phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045321"(leukocyte activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR035892|interpro:IPR037301|interpro:IPR041799|rcsb pdb:1WGL|rcsb pdb:2N31|reactome:R-HSA-6798695|reactome:R-HSA-9020702|refseq:NP_061882.2|refseq:NP_001305441.1|refseq:NP_001305443.1|refseq:NP_001305444.1|refseq:NP_001305445.1|dip:DIP-30845N	ensembl:ENSG00000101460(gene)|ensembl:ENST00000360668(transcript)|ensembl:ENST00000397709(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043278"(response to morphine)|go:"GO:0044754"(autolysosome)|go:"GO:0045202"(synapse)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q9H492|rcsb pdb:3ECI|rcsb pdb:3WAL|rcsb pdb:3WAN|rcsb pdb:4ZDV|rcsb pdb:5CX3|rcsb pdb:5DPR|rcsb pdb:6TBE|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8934903|refseq:NP_115903.1|refseq:NP_852610.1|ensembl:ENSP00000353886|ensembl:ENST00000374837|ensembl:ENSP00000363970|ensembl:ENSP00000380821|dip:DIP-49052N	-	-	-	figure legend:Supp. Fig. 6A|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/27	2014/11/14	rogid:HR6/CGVYMtuDqxW44fBD/KjScnk9606	rogid:qtZ3YM26FhxTs/gW+KFMllsVhn49606	intact-crc:88ABE40259723AF9|rigid:9QgiPdI247C5M0/JdJhUxeEiMIg	false	flag tag:n-n	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H492	uniprotkb:Q9H0E2	intact:EBI-720768|intact:EBI-28977435|ensembl:ENSP00000353886|ensembl:ENSP00000380821|uniprotkb:Q9BXW5|uniprotkb:E1P5P4|uniprotkb:E1P5P5	intact:EBI-74615|ensembl:ENSP00000314733|uniprotkb:Q9H9E6|uniprotkb:Q9UJ69|uniprotkb:B3KXC6	psi-mi:mlp3a_human(display_long)|uniprotkb:Microtubule-associated protein 1 light chain 3 alpha(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 A(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 1(gene name synonym)|uniprotkb:Autophagy-related protein LC3 A(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 A(gene name synonym)|uniprotkb:MAP1LC3A(gene name)|psi-mi:MAP1LC3A(display_short)	psi-mi:tolip_human(display_long)|uniprotkb:TOLLIP(gene name)|psi-mi:TOLLIP(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9975821|imex:IM-23241-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101460(gene)|ensembl:ENST00000360668(transcript)|ensembl:ENST00000397709(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043278"(response to morphine)|go:"GO:0044754"(autolysosome)|go:"GO:0045202"(synapse)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q9H492|rcsb pdb:3ECI|rcsb pdb:3WAL|rcsb pdb:3WAN|rcsb pdb:4ZDV|rcsb pdb:5CX3|rcsb pdb:5DPR|rcsb pdb:6TBE|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8934903|refseq:NP_115903.1|refseq:NP_852610.1|ensembl:ENSP00000353886|ensembl:ENST00000374837|ensembl:ENSP00000363970|ensembl:ENSP00000380821|dip:DIP-49052N	ensembl:ENSG00000078902(gene)|ensembl:ENST00000317204(transcript)|go:"GO:0005150"(interleukin-1, type I receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0016310"(phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045321"(leukocyte activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR035892|interpro:IPR037301|interpro:IPR041799|rcsb pdb:1WGL|rcsb pdb:2N31|reactome:R-HSA-6798695|reactome:R-HSA-9020702|refseq:NP_061882.2|refseq:NP_001305441.1|refseq:NP_001305443.1|refseq:NP_001305444.1|refseq:NP_001305445.1|dip:DIP-30845N	-	-	-	figure legend:Fig. 6B|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/27	2014/11/14	rogid:qtZ3YM26FhxTs/gW+KFMllsVhn49606	rogid:HR6/CGVYMtuDqxW44fBD/KjScnk9606	intact-crc:6F1A03B569694CD5|rigid:9QgiPdI247C5M0/JdJhUxeEiMIg	false	green fluorescent protein tag:n-n	mutation disrupting interaction strength:133-136,151-154|flag tag:n-n|mutation decreasing interaction strength:133-136|mutation decreasing interaction strength:151-154	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H0E2	uniprotkb:Q14596	intact:EBI-74615|ensembl:ENSP00000314733|uniprotkb:Q9H9E6|uniprotkb:Q9UJ69|uniprotkb:B3KXC6	intact:EBI-742698|uniprotkb:Q13173|uniprotkb:Q15026|uniprotkb:Q96GB6|uniprotkb:Q9NRF7|uniprotkb:Q5J7Q8|intact:EBI-2859623|ensembl:ENSP00000343479|ensembl:ENSP00000466667	psi-mi:tolip_human(display_long)|uniprotkb:TOLLIP(gene name)|psi-mi:TOLLIP(display_short)	psi-mi:nbr1_human(display_long)|uniprotkb:Neighbor of BRCA1 gene 1 protein(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 2(gene name synonym)|uniprotkb:Protein 1A1-3B(gene name synonym)|uniprotkb:NBR1(gene name)|psi-mi:NBR1(display_short)|uniprotkb:1A13B(gene name synonym)|uniprotkb:KIAA0049(gene name synonym)|uniprotkb:M17S2(gene name synonym)|uniprotkb:Cell migration-inducing gene 19 protein(gene name synonym)|uniprotkb:MIG19(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9975892|imex:IM-23241-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078902(gene)|ensembl:ENST00000317204(transcript)|go:"GO:0005150"(interleukin-1, type I receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0016310"(phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045321"(leukocyte activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR035892|interpro:IPR037301|interpro:IPR041799|rcsb pdb:1WGL|rcsb pdb:2N31|reactome:R-HSA-6798695|reactome:R-HSA-9020702|refseq:NP_061882.2|refseq:NP_001305441.1|refseq:NP_001305443.1|refseq:NP_001305444.1|refseq:NP_001305445.1|dip:DIP-30845N	refseq:NP_005890.2|refseq:NP_114068.1|ensembl:ENST00000341165(transcript)|ensembl:ENST00000590996(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016604"(nuclear body)|ensembl:ENSG00000188554(gene)|refseq:XP_011523115.1|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0031430"(M band)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR032350|interpro:IPR033513|interpro:IPR034852|interpro:IPR043145|mint:Q14596|rcsb pdb:1WJ6|rcsb pdb:2BKF|rcsb pdb:2CP8|rcsb pdb:2G4S|rcsb pdb:2L8J|rcsb pdb:2MGW|rcsb pdb:2MJ5|rcsb pdb:4OLE|reactome:R-HSA-9664873|refseq:NP_001278500.1|refseq:NP_001278501.1|refseq:XP_016880131.1	-	-	-	figure legend:Supp. Fig. 7I|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/27	2014/11/14	rogid:HR6/CGVYMtuDqxW44fBD/KjScnk9606	rogid:rRlRq4sK4fkVQCliQ68/MIEOX6g9606	intact-crc:0904225A454CD30E|rigid:u7m1rC0PeyFgwtVfuEqO99838N8	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H0E2	uniprotkb:Q13501	intact:EBI-74615|ensembl:ENSP00000314733|uniprotkb:Q9H9E6|uniprotkb:Q9UJ69|uniprotkb:B3KXC6	intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455	psi-mi:tolip_human(display_long)|uniprotkb:TOLLIP(gene name)|psi-mi:TOLLIP(display_short)	psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2014)	pubmed:25042851|imex:IM-23241	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9975892|imex:IM-23241-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078902(gene)|ensembl:ENST00000317204(transcript)|go:"GO:0005150"(interleukin-1, type I receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0016310"(phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045321"(leukocyte activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR035892|interpro:IPR037301|interpro:IPR041799|rcsb pdb:1WGL|rcsb pdb:2N31|reactome:R-HSA-6798695|reactome:R-HSA-9020702|refseq:NP_061882.2|refseq:NP_001305441.1|refseq:NP_001305443.1|refseq:NP_001305444.1|refseq:NP_001305445.1|dip:DIP-30845N	ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1	-	-	-	figure legend:Supp. Fig. 7I|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/27	2014/11/14	rogid:HR6/CGVYMtuDqxW44fBD/KjScnk9606	rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606	intact-crc:0904225A454CD30E|rigid:u7m1rC0PeyFgwtVfuEqO99838N8	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)