#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NYP9	uniprotkb:O43482	intact:EBI-1104552|uniprotkb:Q542Z0|ensembl:ENSP00000290130|uniprotkb:B2R562	intact:EBI-536879|uniprotkb:Q96BX7|ensembl:ENSP00000220514	psi-mi:ms18a_human(display_long)|uniprotkb:MIS18A(gene name)|psi-mi:MIS18A(display_short)|uniprotkb:FAPP1-associated protein 1(gene name synonym)|uniprotkb:C21orf46(gene name synonym)|uniprotkb:FASP1(gene name synonym)|uniprotkb:C21orf45(gene name synonym)	psi-mi:ms18b_human(display_long)|uniprotkb:Cancer/testis antigen 86(gene name synonym)|uniprotkb:OIP5(gene name)|psi-mi:OIP5(display_short)|uniprotkb:MIS18B(gene name synonym)|uniprotkb:Opa-interacting protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	McKinley et al. (2014)	pubmed:25036634|imex:IM-23240	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9872142|imex:IM-23240-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061817.1|ensembl:ENST00000290130(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|interpro:IPR004910(Yippee-like protein)|interpro:IPR034752|reactome:R-HSA-606279|ensembl:ENSG00000159055(gene)	refseq:NP_009211.1|refseq:NP_001304789.1|ensembl:ENSG00000104147(gene)|ensembl:ENST00000220514(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007154"(cell communication)|go:"GO:0010369"(chromocenter)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|interpro:IPR004910(Yippee-like protein)|interpro:IPR034752|mint:O43482|reactome:R-HSA-606279	-	-	-	figure legend:Supp. Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2014/10/23	2014/10/24	rogid:dzfhVJeuppOL/OASRY71tyXTAn49606	rogid:ZZnpZveUathbEs380mbpSh5vB7I9606	intact-crc:205A7E57647FC55D|rigid:oZ0G6XQDdw0dp/g5R7zmxipflXg	false	his tag:?-?	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9NYP9	uniprotkb:Q6P0N0	intact:EBI-1104552|uniprotkb:Q542Z0|ensembl:ENSP00000290130|uniprotkb:B2R562	intact:EBI-9870821|uniprotkb:D3DSA7|uniprotkb:Q86V14|uniprotkb:Q96PY4|uniprotkb:Q9NUR5|uniprotkb:Q9Y4X9|ensembl:ENSP00000309790	psi-mi:ms18a_human(display_long)|uniprotkb:MIS18A(gene name)|psi-mi:MIS18A(display_short)|uniprotkb:FAPP1-associated protein 1(gene name synonym)|uniprotkb:C21orf46(gene name synonym)|uniprotkb:FASP1(gene name synonym)|uniprotkb:C21orf45(gene name synonym)	psi-mi:m18bp_human(display_long)|uniprotkb:MIS18BP1(gene name)|psi-mi:MIS18BP1(display_short)|uniprotkb:C14orf106(gene name synonym)|uniprotkb:KIAA1903(gene name synonym)|uniprotkb:KNL2(gene name synonym)|uniprotkb:M18BP1(gene name synonym)|uniprotkb:Kinetochore-associated protein KNL-2 homolog(gene name synonym)|uniprotkb:P243(gene name synonym)	psi-mi:"MI:0096"(pull down)	McKinley et al. (2014)	pubmed:25036634|imex:IM-23240	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9872142|imex:IM-23240-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061817.1|ensembl:ENST00000290130(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|interpro:IPR004910(Yippee-like protein)|interpro:IPR034752|reactome:R-HSA-606279|ensembl:ENSG00000159055(gene)	refseq:NP_060823.3|refseq:XP_005267890.1|refseq:XP_016876914.1|ensembl:ENSG00000129534(gene)|ensembl:ENST00000310806(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015216(SANT associated)|interpro:IPR017884|interpro:IPR017930|interpro:IPR039110|rcsb pdb:1WGX|reactome:R-HSA-606279	-	-	-	figure legend:Supp. Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2014/10/23	2014/10/24	rogid:dzfhVJeuppOL/OASRY71tyXTAn49606	rogid:/2olIhyXaHJDtS5Yrj3zI8I/d+09606	intact-crc:205A7E57647FC55D|rigid:oZ0G6XQDdw0dp/g5R7zmxipflXg	false	his tag:?-?	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9NYP9	uniprotkb:Q6P0N0	intact:EBI-1104552|uniprotkb:Q542Z0|ensembl:ENSP00000290130|uniprotkb:B2R562	intact:EBI-9870821|uniprotkb:D3DSA7|uniprotkb:Q86V14|uniprotkb:Q96PY4|uniprotkb:Q9NUR5|uniprotkb:Q9Y4X9|ensembl:ENSP00000309790	psi-mi:ms18a_human(display_long)|uniprotkb:MIS18A(gene name)|psi-mi:MIS18A(display_short)|uniprotkb:FAPP1-associated protein 1(gene name synonym)|uniprotkb:C21orf46(gene name synonym)|uniprotkb:FASP1(gene name synonym)|uniprotkb:C21orf45(gene name synonym)	psi-mi:m18bp_human(display_long)|uniprotkb:MIS18BP1(gene name)|psi-mi:MIS18BP1(display_short)|uniprotkb:C14orf106(gene name synonym)|uniprotkb:KIAA1903(gene name synonym)|uniprotkb:KNL2(gene name synonym)|uniprotkb:M18BP1(gene name synonym)|uniprotkb:Kinetochore-associated protein KNL-2 homolog(gene name synonym)|uniprotkb:P243(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	McKinley et al. (2014)	pubmed:25036634|imex:IM-23240	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9872087|imex:IM-23240-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061817.1|ensembl:ENST00000290130(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|interpro:IPR004910(Yippee-like protein)|interpro:IPR034752|reactome:R-HSA-606279|ensembl:ENSG00000159055(gene)	refseq:NP_060823.3|refseq:XP_005267890.1|refseq:XP_016876914.1|ensembl:ENSG00000129534(gene)|ensembl:ENST00000310806(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015216(SANT associated)|interpro:IPR017884|interpro:IPR017930|interpro:IPR039110|rcsb pdb:1WGX|reactome:R-HSA-606279	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/23	2014/10/24	rogid:dzfhVJeuppOL/OASRY71tyXTAn49606	rogid:/2olIhyXaHJDtS5Yrj3zI8I/d+09606	intact-crc:F46D5DC3FA16B70E|rigid:MJ/NjMBcoLaH56Uy6NwuGAdZ81o	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NYP9	uniprotkb:P53350	intact:EBI-1104552|uniprotkb:Q542Z0|ensembl:ENSP00000290130|uniprotkb:B2R562	intact:EBI-476768|uniprotkb:Q15153|uniprotkb:Q99746|ensembl:ENSP00000300093	psi-mi:ms18a_human(display_long)|uniprotkb:MIS18A(gene name)|psi-mi:MIS18A(display_short)|uniprotkb:FAPP1-associated protein 1(gene name synonym)|uniprotkb:C21orf46(gene name synonym)|uniprotkb:FASP1(gene name synonym)|uniprotkb:C21orf45(gene name synonym)	psi-mi:plk1_human(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:PLK1(gene name)|psi-mi:PLK1(display_short)|uniprotkb:PLK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	McKinley et al. (2014)	pubmed:25036634|imex:IM-23240	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9872087|imex:IM-23240-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061817.1|ensembl:ENST00000290130(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|interpro:IPR004910(Yippee-like protein)|interpro:IPR034752|reactome:R-HSA-606279|ensembl:ENSG00000159055(gene)	refseq:NP_005021.2|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|ensembl:ENSG00000166851(gene)|ensembl:ENST00000300093(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0005524"(ATP binding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|rcsb pdb:4DFW|rcsb pdb:4E67|rcsb pdb:4E9C|rcsb pdb:4E9D|rcsb pdb:4H5X|rcsb pdb:4H71|rcsb pdb:4HAB|rcsb pdb:4HCO|rcsb pdb:4HY2|rcsb pdb:4J52|rcsb pdb:4J53|rcsb pdb:4LKL|rcsb pdb:4LKM|rcsb pdb:4O56|rcsb pdb:4O6W|rcsb pdb:4O9W|rcsb pdb:4RCP|rcsb pdb:4WHH|rcsb pdb:4WHK|rcsb pdb:4WHL|rcsb pdb:4X9R|rcsb pdb:4X9V|rcsb pdb:4X9W|rcsb pdb:5J19|rcsb pdb:5NEI|rcsb pdb:5NFU|rcsb pdb:5NJE|rcsb pdb:5NMM|rcsb pdb:5NN1|rcsb pdb:5NN2|rcsb pdb:5TA6|rcsb pdb:5TA8|rcsb pdb:6AX4|rcsb pdb:6GY2|reactome:R-HSA-141444|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174178|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-68881|reactome:R-HSA-68884|reactome:R-HSA-69273|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:P53350|rcsb pdb:1Q4K|rcsb pdb:1Q4O|rcsb pdb:1UMW|rcsb pdb:2OGQ|rcsb pdb:2OJX|rcsb pdb:2OU7|rcsb pdb:2OWB|rcsb pdb:2RKU|rcsb pdb:2V5Q|rcsb pdb:2YAC|rcsb pdb:3BZI|rcsb pdb:3C5L|rcsb pdb:3FC2|rcsb pdb:3FVH|rcsb pdb:3HIH|rcsb pdb:3HIK|rcsb pdb:3KB7|rcsb pdb:3P2W|rcsb pdb:3P2Z|rcsb pdb:3P34|rcsb pdb:3P35|rcsb pdb:3P36|rcsb pdb:3P37|rcsb pdb:3Q1I|rcsb pdb:3RQ7|rcsb pdb:3THB|rcsb pdb:4A4L|rcsb pdb:4A4O|dip:DIP-29696N	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/23	2014/10/24	rogid:dzfhVJeuppOL/OASRY71tyXTAn49606	rogid:fBOK366hV6mDprx9IWhz43gPcJE9606	intact-crc:F46D5DC3FA16B70E|rigid:MJ/NjMBcoLaH56Uy6NwuGAdZ81o	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NYP9	uniprotkb:O43482	intact:EBI-1104552|uniprotkb:Q542Z0|ensembl:ENSP00000290130|uniprotkb:B2R562	intact:EBI-536879|uniprotkb:Q96BX7|ensembl:ENSP00000220514	psi-mi:ms18a_human(display_long)|uniprotkb:MIS18A(gene name)|psi-mi:MIS18A(display_short)|uniprotkb:FAPP1-associated protein 1(gene name synonym)|uniprotkb:C21orf46(gene name synonym)|uniprotkb:FASP1(gene name synonym)|uniprotkb:C21orf45(gene name synonym)	psi-mi:ms18b_human(display_long)|uniprotkb:Cancer/testis antigen 86(gene name synonym)|uniprotkb:OIP5(gene name)|psi-mi:OIP5(display_short)|uniprotkb:MIS18B(gene name synonym)|uniprotkb:Opa-interacting protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	McKinley et al. (2014)	pubmed:25036634|imex:IM-23240	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9872087|imex:IM-23240-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061817.1|ensembl:ENST00000290130(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|interpro:IPR004910(Yippee-like protein)|interpro:IPR034752|reactome:R-HSA-606279|ensembl:ENSG00000159055(gene)	refseq:NP_009211.1|refseq:NP_001304789.1|ensembl:ENSG00000104147(gene)|ensembl:ENST00000220514(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007154"(cell communication)|go:"GO:0010369"(chromocenter)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|interpro:IPR004910(Yippee-like protein)|interpro:IPR034752|mint:O43482|reactome:R-HSA-606279	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/23	2014/10/24	rogid:dzfhVJeuppOL/OASRY71tyXTAn49606	rogid:ZZnpZveUathbEs380mbpSh5vB7I9606	intact-crc:F46D5DC3FA16B70E|rigid:MJ/NjMBcoLaH56Uy6NwuGAdZ81o	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
reactome:R-HSA-606346	uniprotkb:P53350	intact:EBI-9872194	intact:EBI-476768|uniprotkb:Q15153|uniprotkb:Q99746|ensembl:ENSP00000300093	psi-mi:mis18_human(display_short)|psi-mi:R-HSA-606346(display_long)|intact:Mis18 complex(complex recommended name)|intact:"MIS18A:MIS18B:MIS18BP1"(complex systematic name)	psi-mi:plk1_human(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:PLK1(gene name)|psi-mi:PLK1(display_short)|uniprotkb:PLK(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	McKinley et al. (2014)	pubmed:25036634|imex:IM-23240	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9873600|imex:IM-23240-3	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:1302"(stable complex)	psi-mi:"MI:0326"(protein)	go:"GO:0034508"(centromere complex assembly)|go:"GO:0098654"(CENP-A recruiting complex)|go:"GO:1903099"(positive regulation of CENP-A containing nucleosome assembly)|evidence ontology:"ECO:0005547"|pubmed:25202874(see-also)|complex portal:CPX-3272(complex-primary)	refseq:NP_005021.2|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|ensembl:ENSG00000166851(gene)|ensembl:ENST00000300093(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0005524"(ATP binding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|rcsb pdb:4DFW|rcsb pdb:4E67|rcsb pdb:4E9C|rcsb pdb:4E9D|rcsb pdb:4H5X|rcsb pdb:4H71|rcsb pdb:4HAB|rcsb pdb:4HCO|rcsb pdb:4HY2|rcsb pdb:4J52|rcsb pdb:4J53|rcsb pdb:4LKL|rcsb pdb:4LKM|rcsb pdb:4O56|rcsb pdb:4O6W|rcsb pdb:4O9W|rcsb pdb:4RCP|rcsb pdb:4WHH|rcsb pdb:4WHK|rcsb pdb:4WHL|rcsb pdb:4X9R|rcsb pdb:4X9V|rcsb pdb:4X9W|rcsb pdb:5J19|rcsb pdb:5NEI|rcsb pdb:5NFU|rcsb pdb:5NJE|rcsb pdb:5NMM|rcsb pdb:5NN1|rcsb pdb:5NN2|rcsb pdb:5TA6|rcsb pdb:5TA8|rcsb pdb:6AX4|rcsb pdb:6GY2|reactome:R-HSA-141444|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174178|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-68881|reactome:R-HSA-68884|reactome:R-HSA-69273|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:P53350|rcsb pdb:1Q4K|rcsb pdb:1Q4O|rcsb pdb:1UMW|rcsb pdb:2OGQ|rcsb pdb:2OJX|rcsb pdb:2OU7|rcsb pdb:2OWB|rcsb pdb:2RKU|rcsb pdb:2V5Q|rcsb pdb:2YAC|rcsb pdb:3BZI|rcsb pdb:3C5L|rcsb pdb:3FC2|rcsb pdb:3FVH|rcsb pdb:3HIH|rcsb pdb:3HIK|rcsb pdb:3KB7|rcsb pdb:3P2W|rcsb pdb:3P2Z|rcsb pdb:3P34|rcsb pdb:3P35|rcsb pdb:3P36|rcsb pdb:3P37|rcsb pdb:3Q1I|rcsb pdb:3RQ7|rcsb pdb:3THB|rcsb pdb:4A4L|rcsb pdb:4A4O|dip:DIP-29696N	-	curated-complex:"Orchestrates the deposition of CENP-A, the centromere-specific histone H3 variant which is required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. The redistribution of CENP-A nucleosomes between the two new DNA strands is necessary to maintain the epigenetic mark of the centromere and leads to the dilution of CENP-A nucleosomes. The Mis18 complex localizes to centromeres just prior to the pre-nucleosomal HJURP/CENP-A/H4 complex and is absolutely required for the CENP-A-specific chaperone, Holliday junction recognition protein (HJURP, Q8NCD3) to reach the centromeres. CDK phosphorylation of MISBP1 during G2 and mitosis, prior to the metaphase-to-anaphase transition, negatively regulates complex assembly. Plk1 phosphorylation activates Mis18 complex recruitment to the centromeres during G1."	-	figure legend:Supp. Fig. 4B, 4C|resulting-ptm:EBI-9872194 Q6P0N0 ser-93 O-phospho-L-serine|resulting-ptm:EBI-9872194 Q6P0N0 ser-179 O-phospho-L-serine|resulting-ptm:EBI-9872194 Q6P0N0 ser-192 O-phospho-L-serine|resulting-ptm:EBI-9872194 Q6P0N0 ser-218 O-phospho-L-serine|resulting-ptm:EBI-9872194 Q6P0N0 thr-570 O-phospho-L-threonine|resulting-ptm:EBI-9872194 Q6P0N0 ser-622 O-phospho-L-serine|resulting-ptm:EBI-9872194 Q6P0N0 thr-702 O-phospho-L-threonine|resulting-ptm:EBI-9872194 Q6P0N0 ser-1104 O-phospho-L-serine|resulting-ptm:EBI-9872194 Q9NYP9 ser-53 O-phospho-L-serine|resulting-ptm:EBI-9872194 Q9NYP9 ser-54 O-phospho-L-serine|resulting-ptm:EBI-9872194 Q9NYP9 ser-56 O-phospho-L-serine|resulting-ptm:EBI-9872194 Q9NYP9 ser-60 O-phospho-L-serine|resulting-ptm:EBI-9872194 Q9NYP9 ser-204 O-phospho-L-serine|resulting-ptm:EBI-9872194 Q9NYP9 thr-206 O-phospho-L-threonine|resulting-ptm:EBI-9872194 O43482 thr-221 O-phospho-L-threonine|resulting-ptm:EBI-9872194 O43482 ser-225 O-phospho-L-serine|causality statement:P53350 increases activity of EBI-9872194|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/10/23	2016/06/23	-	rogid:fBOK366hV6mDprx9IWhz43gPcJE9606	intact-crc:320BF164C2AC4469	false	his tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P53350	intact:EBI-9873644	intact:EBI-476768|uniprotkb:Q15153|uniprotkb:Q99746|ensembl:ENSP00000300093	-	psi-mi:plk1_human(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:PLK1(gene name)|psi-mi:PLK1(display_short)|uniprotkb:PLK(gene name synonym)	psi-mi:mis18_mouse(display_short)|psi-mi:EBI-9873644(display_long)|intact:Mis18 complex(complex recommended name)|intact:"Mis18a:Mis18b:Mis18bp1"(complex systematic name)	psi-mi:"MI:0047"(far western blotting)	McKinley et al. (2014)	pubmed:25036634|imex:IM-23240	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9873654|imex:IM-23240-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:1302"(stable complex)	refseq:NP_005021.2|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|ensembl:ENSG00000166851(gene)|ensembl:ENST00000300093(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0005524"(ATP binding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|rcsb pdb:4DFW|rcsb pdb:4E67|rcsb pdb:4E9C|rcsb pdb:4E9D|rcsb pdb:4H5X|rcsb pdb:4H71|rcsb pdb:4HAB|rcsb pdb:4HCO|rcsb pdb:4HY2|rcsb pdb:4J52|rcsb pdb:4J53|rcsb pdb:4LKL|rcsb pdb:4LKM|rcsb pdb:4O56|rcsb pdb:4O6W|rcsb pdb:4O9W|rcsb pdb:4RCP|rcsb pdb:4WHH|rcsb pdb:4WHK|rcsb pdb:4WHL|rcsb pdb:4X9R|rcsb pdb:4X9V|rcsb pdb:4X9W|rcsb pdb:5J19|rcsb pdb:5NEI|rcsb pdb:5NFU|rcsb pdb:5NJE|rcsb pdb:5NMM|rcsb pdb:5NN1|rcsb pdb:5NN2|rcsb pdb:5TA6|rcsb pdb:5TA8|rcsb pdb:6AX4|rcsb pdb:6GY2|reactome:R-HSA-141444|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174178|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-68881|reactome:R-HSA-68884|reactome:R-HSA-69273|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:P53350|rcsb pdb:1Q4K|rcsb pdb:1Q4O|rcsb pdb:1UMW|rcsb pdb:2OGQ|rcsb pdb:2OJX|rcsb pdb:2OU7|rcsb pdb:2OWB|rcsb pdb:2RKU|rcsb pdb:2V5Q|rcsb pdb:2YAC|rcsb pdb:3BZI|rcsb pdb:3C5L|rcsb pdb:3FC2|rcsb pdb:3FVH|rcsb pdb:3HIH|rcsb pdb:3HIK|rcsb pdb:3KB7|rcsb pdb:3P2W|rcsb pdb:3P2Z|rcsb pdb:3P34|rcsb pdb:3P35|rcsb pdb:3P36|rcsb pdb:3P37|rcsb pdb:3Q1I|rcsb pdb:3RQ7|rcsb pdb:3THB|rcsb pdb:4A4L|rcsb pdb:4A4O|dip:DIP-29696N	go:"GO:1903099"(positive regulation of CENP-A containing nucleosome assembly)|pubmed:25202874(see-also)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0098654"(CENP-A recruiting complex)|evidence ontology:"ECO:0005547"|complex portal:CPX-3273(complex-primary)	-	-	curated-complex:"Orchestrates the deposition of CENP-A, the centromere-specific histone H3 variant which is required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. The redistribution of CENP-A nucleosomes between the two new DNA strands is necessary to maintain the epigenetic mark of the centromere and leads to the dilution of CENP-A nucleosomes. The Mis18 complex localizes to centromeres just prior to the pre-nucleosomal HJURP/CENP-A/H4 complex and is absolutely required for the CENP-A-specific chaperone, Holliday junction recognition protein (HJURP, Q6PG16) to reach the centromeres. CDK phosphorylation of MISBP1 during G2 and mitosis, prior to the metaphase-to-anaphase transition, negatively regulates complex assembly. Plk1 phosphorylation activates Mis18 complex recruitment to the centromeres during G1."	figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/10/23	2014/10/27	rogid:fBOK366hV6mDprx9IWhz43gPcJE9606	-	intact-crc:50D071E8367370B4	false	glutathione s tranferase tag:?-?|sufficient binding region:417..417-584..584(IPR000959)	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)