#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P97479 uniprotkb:P18084 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181 psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short) psi-mi:"MI:0096"(pull down) Liu et al. (2014) pubmed:24997346|imex:IM-22934 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9552141|imex:IM-22934-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794 refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355 - - - figure legend:f2c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606 intact-crc:05F2F1F222812DC5|rigid:37je4JtOUH78DEwIYQQNmchHVj8 false binding-associated region:1247-1556|flag tag:?-? glutathione s tranferase tag:?-?|binding-associated region:743-799 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P18084 uniprotkb:P97479 intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short) psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:"MI:0096"(pull down) Liu et al. (2014) pubmed:24997346|imex:IM-22934 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9552127|imex:IM-22934-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355 refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794 - - - figure legend:f2c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 intact-crc:E405784E9A0118A7|rigid:37je4JtOUH78DEwIYQQNmchHVj8 false binding-associated region:743-799|glutathione s tranferase tag:?-? binding-associated region:1853-2156|flag tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P97479 uniprotkb:P18084 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181 psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short) psi-mi:"MI:0096"(pull down) Liu et al. (2014) pubmed:24997346|imex:IM-22934 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9552155|imex:IM-22934-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794 refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355 - - - figure legend:f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606 intact-crc:8FA8E28DB8311A5E|rigid:37je4JtOUH78DEwIYQQNmchHVj8 false binding-associated region:1853-2156|maltose binding protein tag:?-? glutathione s tranferase tag:?-?|binding-associated region:743-799 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P18084 uniprotkb:P97479 intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short) psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:"MI:0096"(pull down) Liu et al. (2014) pubmed:24997346|imex:IM-22934 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9552169|imex:IM-22934-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355 refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794 - - - figure legend:f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 intact-crc:85931D86E75FD815|rigid:37je4JtOUH78DEwIYQQNmchHVj8 false binding-associated region:743-799|glutathione s tranferase tag:?-? binding-associated region:1247-1556|maltose binding protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P97479 uniprotkb:P18084 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181 psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short) psi-mi:"MI:0096"(pull down) Liu et al. (2014) pubmed:24997346|imex:IM-22934 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9551747|imex:IM-22934-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794 refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355 - - - figure legend:f1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606 intact-crc:D58D492AC21F2B93|rigid:37je4JtOUH78DEwIYQQNmchHVj8 false - binding-associated region:743-799|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P18084 uniprotkb:P97479 intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short) psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:"MI:0096"(pull down) Liu et al. (2014) pubmed:24997346|imex:IM-22934 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9552113|imex:IM-22934-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355 refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794 - - - figure legend:f2b f2f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 intact-crc:87FE28552844C84E|rigid:37je4JtOUH78DEwIYQQNmchHVj8 false glutathione s tranferase tag:?-?|binding-associated region:743-799 binding-associated region:1853-1963|green fluorescent protein tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P18084 uniprotkb:P97479 intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short) psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:"MI:0096"(pull down) Liu et al. (2014) pubmed:24997346|imex:IM-22934 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9552099|imex:IM-22934-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355 refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794 - - - figure legend:f2b f2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 intact-crc:7FA4D27CA9B341F2|rigid:37je4JtOUH78DEwIYQQNmchHVj8 false glutathione s tranferase tag:?-?|binding-associated region:743-799 green fluorescent protein tag:?-?|binding-associated region:1430-1556 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P97479 uniprotkb:P18084 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181 psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short) psi-mi:"MI:0096"(pull down) Liu et al. (2014) pubmed:24997346|imex:IM-22934 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9551689|imex:IM-22934-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794 refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355 - - - figure legend:f1b f1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606 intact-crc:FD6E457ED9CCF92A|rigid:37je4JtOUH78DEwIYQQNmchHVj8 false binding-associated region:1006-2166|flag tag:?-? glutathione s tranferase tag:?-?|binding-associated region:743-799 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O70309 uniprotkb:P97479 intact:EBI-8401821|intact:MINT-4099048|uniprotkb:O70308|uniprotkb:O88347 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 psi-mi:itb5_mouse(display_long)|uniprotkb:Itgb5(gene name)|psi-mi:Itgb5(display_short) psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2014) pubmed:24997346|imex:IM-22934 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9552089|imex:IM-22934-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032695|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR015812(Integrin beta subunit)|refseq:NP_034710.2|refseq:NP_001139356.1|interpro:IPR033760|interpro:IPR040622|interpro:IPR036349|interpro:IPR036465|mint:O70309|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|reactome:R-MMU-1236973|reactome:R-MMU-2129379|reactome:R-MMU-216083|reactome:R-MMU-3000170|reactome:R-MMU-3000178|reactome:R-MMU-445355|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail) refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794 - comment:mint|function:Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand - figure legend:f1f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-b16)|taxid:10090(Mus musculus melanoma tumor maintained in mouse.) - 2014/06/18 2014/10/16 rogid:2e0Ey59Y4DVqezxGIKb7ajwfWjg10090 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 intact-crc:153621746CD1A6A8|rigid:P4Rn6k3D7jZRyG4k4pS41TmbpgM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O70309 uniprotkb:P97479 intact:EBI-8401821|intact:MINT-4099048|uniprotkb:O70308|uniprotkb:O88347 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 psi-mi:itb5_mouse(display_long)|uniprotkb:Itgb5(gene name)|psi-mi:Itgb5(display_short) psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2014) pubmed:24997346|imex:IM-22934 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9552069|imex:IM-22934-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032695|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR015812(Integrin beta subunit)|refseq:NP_034710.2|refseq:NP_001139356.1|interpro:IPR033760|interpro:IPR040622|interpro:IPR036349|interpro:IPR036465|mint:O70309|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|reactome:R-MMU-1236973|reactome:R-MMU-2129379|reactome:R-MMU-216083|reactome:R-MMU-3000170|reactome:R-MMU-3000178|reactome:R-MMU-445355|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail) refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794 - comment:mint|function:Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand - figure legend:f1e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-b16)|taxid:10090(Mus musculus melanoma tumor maintained in mouse.) - 2014/06/18 2014/10/16 rogid:2e0Ey59Y4DVqezxGIKb7ajwfWjg10090 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 intact-crc:44BB15D85A2352C4|rigid:P4Rn6k3D7jZRyG4k4pS41TmbpgM false - binding-associated region:1006-2166|flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O70309 uniprotkb:P97479 intact:EBI-8401821|intact:MINT-4099048|uniprotkb:O70308|uniprotkb:O88347 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 psi-mi:itb5_mouse(display_long)|uniprotkb:Itgb5(gene name)|psi-mi:Itgb5(display_short) psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2014) pubmed:24997346|imex:IM-22934 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9552079|imex:IM-22934-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032695|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR015812(Integrin beta subunit)|refseq:NP_034710.2|refseq:NP_001139356.1|interpro:IPR033760|interpro:IPR040622|interpro:IPR036349|interpro:IPR036465|mint:O70309|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|reactome:R-MMU-1236973|reactome:R-MMU-2129379|reactome:R-MMU-216083|reactome:R-MMU-3000170|reactome:R-MMU-3000178|reactome:R-MMU-445355|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail) refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794 - comment:mint|function:Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand - figure legend:f1e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-b16)|taxid:10090(Mus musculus melanoma tumor maintained in mouse.) - 2014/06/18 2014/10/16 rogid:2e0Ey59Y4DVqezxGIKb7ajwfWjg10090 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 intact-crc:1534F1746CD1A6A8|rigid:P4Rn6k3D7jZRyG4k4pS41TmbpgM false - flag tag:?-?|binding-associated region:1006-2166 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot)