#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UPV9 uniprotkb:Q2PQA9 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 intact:EBI-920191|uniprotkb:Q9WV65|ensembl:ENSRNOP00000023860 psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:kinh_rat(display_long)|uniprotkb:Kif5b(gene name)|psi-mi:Kif5b(display_short)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)|uniprotkb:Khc(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9846297|imex:IM-23273-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 rgd:621559|refseq:NP_476550.1|refseq:XP_006254067.1|ensembl:ENSRNOG00000017466(gene)|ensembl:ENSRNOT00000023861(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0021766"(hippocampus development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q2PQA9|rcsb pdb:4ATX|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189|dip:DIP-37054N - - - figure legend:Supp. Fig. 4E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/11/10 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 rogid:OjHE/OLj2diwiW5HI0HFHEDkbjY10116 intact-crc:C2A3FCA392B5B419|rigid:1M1ouSFuCwiGaytt/H+rb4woJvs false myc tag:?-?|sufficient binding region:1-657,682-770,860-953 yellow fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UPV9 uniprotkb:P56558 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 intact:EBI-7614183|intact:UNK-5380836 psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:ogt1_rat(display_long)|uniprotkb:Ogt(gene name)|psi-mi:Ogt(display_short)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9846134|imex:IM-23273-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 mint:P56558|refseq:NP_058803.2|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|rgd:62060|interpro:IPR019734|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006041"(glucosamine metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0042277"(peptide binding)|go:"GO:0042588"(zymogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|reactome:R-RNO-3214847|reactome:R-RNO-5675482|reactome:R-RNO-5689603|go:"GO:0032922"(circadian regulation of gene expression)|interpro:IPR029489|interpro:IPR037919 - - comment:mint|function:Addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine figure legend:Fig. 3F, 3H|comment:Over-expression of rat OGT1 causes increased O-GlcNAcylation of TRAK1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/10/16 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 rogid:sCf6MLtjXm2GFIlQQKKO3EJmuag10116 intact-crc:2C937B172EBF1F25|rigid:rk3BPfk/m0RjKG3FHS0bo7YCBYU false myc tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UPV9 uniprotkb:O15294 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9846134|imex:IM-23273-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N - - - figure legend:Fig. 3F, 3H|comment:Over-expression of rat OGT1 causes increased O-GlcNAcylation of TRAK1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/10/16 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 intact-crc:2C937B172EBF1F25|rigid:rk3BPfk/m0RjKG3FHS0bo7YCBYU false myc tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P56558 uniprotkb:Q9UPV9 intact:EBI-7614183|intact:UNK-5380836 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 psi-mi:ogt1_rat(display_long)|uniprotkb:Ogt(gene name)|psi-mi:Ogt(display_short)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym) psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9846172|imex:IM-23273-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P56558|refseq:NP_058803.2|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|rgd:62060|interpro:IPR019734|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006041"(glucosamine metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0042277"(peptide binding)|go:"GO:0042588"(zymogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|reactome:R-RNO-3214847|reactome:R-RNO-5675482|reactome:R-RNO-5689603|go:"GO:0032922"(circadian regulation of gene expression)|interpro:IPR029489|interpro:IPR037919 ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 - comment:mint|function:Addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine - figure legend:Fig. 3F, 3H, 4C, Supp. 4B|comment:Over-expression of rat OGT1 causes increased O-GlcNAcylation of TRAK1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/10/16 rogid:sCf6MLtjXm2GFIlQQKKO3EJmuag10116 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 intact-crc:319DEB841ED73CC0|rigid:1iWuOGHaSRRVEWYXS3hiqnLCRX0 false - necessary binding region:658-672|myc tag:?-?|sufficient binding region:634-953 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P56558 uniprotkb:Q9UPV9 intact:EBI-7614183|intact:UNK-5380836 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 psi-mi:ogt1_rat(display_long)|uniprotkb:Ogt(gene name)|psi-mi:Ogt(display_short)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym) psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9846204|imex:IM-23273-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P56558|refseq:NP_058803.2|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|rgd:62060|interpro:IPR019734|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006041"(glucosamine metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0042277"(peptide binding)|go:"GO:0042588"(zymogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|reactome:R-RNO-3214847|reactome:R-RNO-5675482|reactome:R-RNO-5689603|go:"GO:0032922"(circadian regulation of gene expression)|interpro:IPR029489|interpro:IPR037919 ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 - comment:mint|function:Addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine - figure legend:Fig. 4G|comment:Deletion of the first 6 TPR domains of rat OGT1 decreased TRAK1 O-GlcNAcylation.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/11/10 rogid:sCf6MLtjXm2GFIlQQKKO3EJmuag10116 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 intact-crc:42C4437AA2952C7E|rigid:1iWuOGHaSRRVEWYXS3hiqnLCRX0 false necessary binding region:248..248-385..385 myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O15294 uniprotkb:Q9UPV9 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9846183|imex:IM-23273-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 - - - figure legend:Figs. 3F, 3H, 4D, 5B|comment:Full-length TRAK1 is weakly O-GlcNAcylated. Although TRAK1 deleted of residues 658–672 no longer bound OGT with sufficient affinity to coprecipitate, its O-GlcNAcylation by OGT was increased|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/11/12 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 intact-crc:B5D7A5632BF4F3B0|rigid:d51GY42M7BJ/Uanic1TwL71V+ns false - myc tag:?-?|necessary binding region:658-672 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q2PQA9 uniprotkb:Q9UPV9 intact:EBI-920191|uniprotkb:Q9WV65|ensembl:ENSRNOP00000023860 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 psi-mi:kinh_rat(display_long)|uniprotkb:Kif5b(gene name)|psi-mi:Kif5b(display_short)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)|uniprotkb:Khc(gene name synonym) psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9824231|imex:IM-23273-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621559|refseq:NP_476550.1|refseq:XP_006254067.1|ensembl:ENSRNOG00000017466(gene)|ensembl:ENSRNOT00000023861(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0021766"(hippocampus development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q2PQA9|rcsb pdb:4ATX|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189|dip:DIP-37054N ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 - - - figure legend:Supp Fig. 3B|comment:Endogenous OGT1 protein immunoprecipitated with TRAK1/Kif5b in the absence of transfected construct.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/10/16 rogid:OjHE/OLj2diwiW5HI0HFHEDkbjY10116 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 intact-crc:3C7C4F66E841442D|rigid:U04TcnA3jMOvgrksIAvjNRJJWXk false yellow fluorescent protein tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q2PQA9 uniprotkb:O15294 intact:EBI-920191|uniprotkb:Q9WV65|ensembl:ENSRNOP00000023860 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 psi-mi:kinh_rat(display_long)|uniprotkb:Kif5b(gene name)|psi-mi:Kif5b(display_short)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)|uniprotkb:Khc(gene name synonym) psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9824231|imex:IM-23273-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621559|refseq:NP_476550.1|refseq:XP_006254067.1|ensembl:ENSRNOG00000017466(gene)|ensembl:ENSRNOT00000023861(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0021766"(hippocampus development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q2PQA9|rcsb pdb:4ATX|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189|dip:DIP-37054N refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N - - - figure legend:Supp Fig. 3B|comment:Endogenous OGT1 protein immunoprecipitated with TRAK1/Kif5b in the absence of transfected construct.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/10/16 rogid:OjHE/OLj2diwiW5HI0HFHEDkbjY10116 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 intact-crc:3C7C4F66E841442D|rigid:U04TcnA3jMOvgrksIAvjNRJJWXk false yellow fluorescent protein tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q2PQA9 uniprotkb:P56558 intact:EBI-920191|uniprotkb:Q9WV65|ensembl:ENSRNOP00000023860 intact:EBI-7614183|intact:UNK-5380836 psi-mi:kinh_rat(display_long)|uniprotkb:Kif5b(gene name)|psi-mi:Kif5b(display_short)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)|uniprotkb:Khc(gene name synonym) psi-mi:ogt1_rat(display_long)|uniprotkb:Ogt(gene name)|psi-mi:Ogt(display_short)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9824222|imex:IM-23273-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621559|refseq:NP_476550.1|refseq:XP_006254067.1|ensembl:ENSRNOG00000017466(gene)|ensembl:ENSRNOT00000023861(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0021766"(hippocampus development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q2PQA9|rcsb pdb:4ATX|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189|dip:DIP-37054N mint:P56558|refseq:NP_058803.2|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|rgd:62060|interpro:IPR019734|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006041"(glucosamine metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0042277"(peptide binding)|go:"GO:0042588"(zymogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|reactome:R-RNO-3214847|reactome:R-RNO-5675482|reactome:R-RNO-5689603|go:"GO:0032922"(circadian regulation of gene expression)|interpro:IPR029489|interpro:IPR037919 - - comment:mint|function:Addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine figure legend:Supp Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/10/16 rogid:OjHE/OLj2diwiW5HI0HFHEDkbjY10116 rogid:sCf6MLtjXm2GFIlQQKKO3EJmuag10116 intact-crc:23EA28F60FE964CA|rigid:23RDcbFGMyuDENCDOlcteBgp0KM false yellow fluorescent protein tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q2PQA9 uniprotkb:Q9UPV9 intact:EBI-920191|uniprotkb:Q9WV65|ensembl:ENSRNOP00000023860 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 psi-mi:kinh_rat(display_long)|uniprotkb:Kif5b(gene name)|psi-mi:Kif5b(display_short)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)|uniprotkb:Khc(gene name synonym) psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9824222|imex:IM-23273-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621559|refseq:NP_476550.1|refseq:XP_006254067.1|ensembl:ENSRNOG00000017466(gene)|ensembl:ENSRNOT00000023861(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0021766"(hippocampus development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q2PQA9|rcsb pdb:4ATX|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189|dip:DIP-37054N ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 - - - figure legend:Supp Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/10/16 rogid:OjHE/OLj2diwiW5HI0HFHEDkbjY10116 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 intact-crc:23EA28F60FE964CA|rigid:23RDcbFGMyuDENCDOlcteBgp0KM false yellow fluorescent protein tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UPV9 uniprotkb:Q8IXI2 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 intact:EBI-1396430|uniprotkb:A4FVB6|uniprotkb:Q6NUR3|uniprotkb:Q6P9F8|uniprotkb:Q6PJG1|uniprotkb:Q6YMW8|uniprotkb:Q86UB0|uniprotkb:Q8IW28|uniprotkb:Q8IXJ7|uniprotkb:Q9H067|uniprotkb:Q9H9N8|uniprotkb:Q9NUZ2|uniprotkb:A6NFV0|uniprotkb:B4DG48|uniprotkb:J9JIH9|ensembl:ENSP00000334724 psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:miro1_human(display_long)|uniprotkb:Ras homolog gene family member T1(gene name synonym)|uniprotkb:Rac-GTP-binding protein-like protein(gene name synonym)|uniprotkb:RHOT1(gene name)|psi-mi:RHOT1(display_short)|uniprotkb:ARHT1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9846061|imex:IM-23273-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 refseq:NP_001028738.1|refseq:NP_001028740.1|refseq:NP_060777.3|refseq:NP_001028739.2|refseq:NP_001275683.1|refseq:NP_001275684.1|refseq:NP_001275687.1|dip:DIP-39114N|ensembl:ENSG00000126858(gene)|ensembl:ENST00000333942(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034640"(establishment of mitochondrion localization by microtubule attachment)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|interpro:IPR029506|mint:Q8IXI2|rcsb pdb:5KSO|rcsb pdb:5KSP|rcsb pdb:5KSY|rcsb pdb:5KSZ|rcsb pdb:5KTY|rcsb pdb:5KU1|rcsb pdb:6D71|reactome:R-HSA-5689880|reactome:R-HSA-9013425 - - - figure legend:Fig. 3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/10/16 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 rogid:gA6A8bgSwshvMwCO0cG66h+wwIY9606 intact-crc:F4244012F7177D76|rigid:cgMUTkmEEajDb9MPEeZmsdGmRhg false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UPV9 uniprotkb:P33176 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 intact:EBI-355878|uniprotkb:A0AVB2|uniprotkb:Q5VZ85|ensembl:ENSP00000307078 psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:kinh_human(display_long)|uniprotkb:KIF5B(gene name)|psi-mi:KIF5B(display_short)|uniprotkb:KNS(gene name synonym)|uniprotkb:KNS1(gene name synonym)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9846061|imex:IM-23273-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 refseq:NP_004512.1|ensembl:ENSG00000170759(gene)|ensembl:ENST00000302418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P33176|rcsb pdb:1BG2|rcsb pdb:1MKJ|rcsb pdb:2P4N|rcsb pdb:3J8X|rcsb pdb:3J8Y|rcsb pdb:4HNA|rcsb pdb:4LNU|rcsb pdb:5LT0|rcsb pdb:5LT1|rcsb pdb:5LT2|rcsb pdb:5LT3|rcsb pdb:5LT4|rcsb pdb:6OJQ|reactome:R-HSA-2132295|reactome:R-HSA-264876|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-29244N - - - figure legend:Fig. 3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/10/16 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 rogid:2UUVZBn5EAd0xBA5IZDPWHX9i7U9606 intact-crc:F4244012F7177D76|rigid:cgMUTkmEEajDb9MPEeZmsdGmRhg false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UPV9 uniprotkb:Q8IXI2 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 intact:EBI-1396430|uniprotkb:A4FVB6|uniprotkb:Q6NUR3|uniprotkb:Q6P9F8|uniprotkb:Q6PJG1|uniprotkb:Q6YMW8|uniprotkb:Q86UB0|uniprotkb:Q8IW28|uniprotkb:Q8IXJ7|uniprotkb:Q9H067|uniprotkb:Q9H9N8|uniprotkb:Q9NUZ2|uniprotkb:A6NFV0|uniprotkb:B4DG48|uniprotkb:J9JIH9|ensembl:ENSP00000334724 psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:miro1_human(display_long)|uniprotkb:Ras homolog gene family member T1(gene name synonym)|uniprotkb:Rac-GTP-binding protein-like protein(gene name synonym)|uniprotkb:RHOT1(gene name)|psi-mi:RHOT1(display_short)|uniprotkb:ARHT1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9845992|imex:IM-23273-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 refseq:NP_001028738.1|refseq:NP_001028740.1|refseq:NP_060777.3|refseq:NP_001028739.2|refseq:NP_001275683.1|refseq:NP_001275684.1|refseq:NP_001275687.1|dip:DIP-39114N|ensembl:ENSG00000126858(gene)|ensembl:ENST00000333942(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034640"(establishment of mitochondrion localization by microtubule attachment)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|interpro:IPR029506|mint:Q8IXI2|rcsb pdb:5KSO|rcsb pdb:5KSP|rcsb pdb:5KSY|rcsb pdb:5KSZ|rcsb pdb:5KTY|rcsb pdb:5KU1|rcsb pdb:6D71|reactome:R-HSA-5689880|reactome:R-HSA-9013425 - - - figure legend:Fig. 3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/10/16 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 rogid:gA6A8bgSwshvMwCO0cG66h+wwIY9606 intact-crc:DFB4268DDCB5D443|rigid:i/uhRbu8r4GTJ1gAPVyPq4YQ1cU false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UPV9 uniprotkb:P56558 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 intact:EBI-7614183|intact:UNK-5380836 psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:ogt1_rat(display_long)|uniprotkb:Ogt(gene name)|psi-mi:Ogt(display_short)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9845992|imex:IM-23273-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 mint:P56558|refseq:NP_058803.2|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|rgd:62060|interpro:IPR019734|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006041"(glucosamine metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0042277"(peptide binding)|go:"GO:0042588"(zymogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|reactome:R-RNO-3214847|reactome:R-RNO-5675482|reactome:R-RNO-5689603|go:"GO:0032922"(circadian regulation of gene expression)|interpro:IPR029489|interpro:IPR037919 - - comment:mint|function:Addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine figure legend:Fig. 3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/10/16 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 rogid:sCf6MLtjXm2GFIlQQKKO3EJmuag10116 intact-crc:DFB4268DDCB5D443|rigid:i/uhRbu8r4GTJ1gAPVyPq4YQ1cU false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UPV9 uniprotkb:P33176 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 intact:EBI-355878|uniprotkb:A0AVB2|uniprotkb:Q5VZ85|ensembl:ENSP00000307078 psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:kinh_human(display_long)|uniprotkb:KIF5B(gene name)|psi-mi:KIF5B(display_short)|uniprotkb:KNS(gene name synonym)|uniprotkb:KNS1(gene name synonym)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9845992|imex:IM-23273-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 refseq:NP_004512.1|ensembl:ENSG00000170759(gene)|ensembl:ENST00000302418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P33176|rcsb pdb:1BG2|rcsb pdb:1MKJ|rcsb pdb:2P4N|rcsb pdb:3J8X|rcsb pdb:3J8Y|rcsb pdb:4HNA|rcsb pdb:4LNU|rcsb pdb:5LT0|rcsb pdb:5LT1|rcsb pdb:5LT2|rcsb pdb:5LT3|rcsb pdb:5LT4|rcsb pdb:6OJQ|reactome:R-HSA-2132295|reactome:R-HSA-264876|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-29244N - - - figure legend:Fig. 3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/10/16 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 rogid:2UUVZBn5EAd0xBA5IZDPWHX9i7U9606 intact-crc:DFB4268DDCB5D443|rigid:i/uhRbu8r4GTJ1gAPVyPq4YQ1cU false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q960V3 uniprotkb:O15294 intact:EBI-162592|intact:EBI-1628668|uniprotkb:Q0E8S6|uniprotkb:Q8SWX2|uniprotkb:Q95NI8|ensemblmetazoa:FBpp0297340 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 psi-mi:milt_drome(display_long)|uniprotkb:milt(gene name)|psi-mi:milt(display_short)|uniprotkb:Protein milton(gene name synonym)|uniprotkb:CG43227(orf name) psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9846153|imex:IM-23273-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542943.2|refseq:NP_723249.1|refseq:NP_723251.1|flybase:FBgn0262872|ensemblmetazoa:FBgn0262872(gene)|ensemblmetazoa:FBtr0306230(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006605"(protein targeting)|go:"GO:0007287"(Nebenkern assembly)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0017022"(myosin binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030382"(sperm mitochondrion organization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|reactome:R-DME-9013419|reactome:R-DME-9013425 refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/10/16 rogid:ij2LvzNB2OxZjxTSiI8NsU0Zugg7227 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 intact-crc:597CC36175446B01|rigid:g4bAIMoSg0Vz8O9CBcdBJdlTNcc false sufficient binding region:451-750 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IXI1 uniprotkb:Q9UPV9 intact:EBI-1396563|uniprotkb:Q8NF53|uniprotkb:Q96C13|uniprotkb:Q96S17|uniprotkb:Q9BT60|uniprotkb:Q9H7M8|uniprotkb:A2IDC2|ensembl:ENSP00000321971 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 psi-mi:miro2_human(display_long)|uniprotkb:RHOT2(gene name)|psi-mi:RHOT2(display_short)|uniprotkb:ARHT2(gene name synonym)|uniprotkb:C16orf39(gene name synonym)|uniprotkb:Ras homolog gene family member T2(gene name synonym) psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9846217|imex:IM-23273-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620124.1|ensembl:ENSG00000140983(gene)|ensembl:ENST00000315082(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|mint:Q8IXI1|rcsb pdb:5KUT|reactome:R-HSA-9013419 ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 - - - figure legend:SUpp. Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/09/24 2014/11/10 rogid:E+WoN8aoND+U/YkLBUTecrNbDXg9606 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 intact-crc:823A7FFCAC77E4BD|rigid:iaiOPRaOKgLT73ZlhLM2cHdQkBw false ha tag:?-? myc tag:?-?|sufficient binding region:1-657,682-770,860-953 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P56558 uniprotkb:Q9UPV9 intact:EBI-7614183|intact:UNK-5380836 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 psi-mi:ogt1_rat(display_long)|uniprotkb:Ogt(gene name)|psi-mi:Ogt(display_short)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym) psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-9974917|imex:IM-23273-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P56558|refseq:NP_058803.2|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|rgd:62060|interpro:IPR019734|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006041"(glucosamine metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0042277"(peptide binding)|go:"GO:0042588"(zymogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|reactome:R-RNO-3214847|reactome:R-RNO-5675482|reactome:R-RNO-5689603|go:"GO:0032922"(circadian regulation of gene expression)|interpro:IPR029489|interpro:IPR037919 ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 go:"GO:0005739"(mitochondrion) comment:mint|function:Addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine - figure legend:Supp Fig. 5I|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-primary_hippocampal_neuron)|taxid:10116(Rat primary hippocampal neuron) - 2014/09/24 2014/11/24 rogid:sCf6MLtjXm2GFIlQQKKO3EJmuag10116 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 intact-crc:0E552E6F5F605118|rigid:1iWuOGHaSRRVEWYXS3hiqnLCRX0 false - myc tag:?-? - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P56558 uniprotkb:Q9UPV9 intact:EBI-7614183|intact:UNK-5380836 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 psi-mi:ogt1_rat(display_long)|uniprotkb:Ogt(gene name)|psi-mi:Ogt(display_short)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym) psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Pekkurnaz et al. (2014) imex:IM-23273|pubmed:24995978 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-9845968|imex:IM-23273-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P56558|refseq:NP_058803.2|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|rgd:62060|interpro:IPR019734|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006041"(glucosamine metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0042277"(peptide binding)|go:"GO:0042588"(zymogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|reactome:R-RNO-3214847|reactome:R-RNO-5675482|reactome:R-RNO-5689603|go:"GO:0032922"(circadian regulation of gene expression)|interpro:IPR029489|interpro:IPR037919 ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1 go:"GO:0005739"(mitochondrion) comment:mint|function:Addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine - figure legend:Supp Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/09/24 2014/10/16 rogid:sCf6MLtjXm2GFIlQQKKO3EJmuag10116 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 intact-crc:56CC907D8A67C4C0|rigid:1iWuOGHaSRRVEWYXS3hiqnLCRX0 false green fluorescent protein tag:n-n myc tag:?-? - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry)