#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12778 uniprotkb:Q01105 intact:EBI-1108782|uniprotkb:O43523|uniprotkb:Q5VYC7|uniprotkb:Q6NSK6|ensembl:ENSP00000368880 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 psi-mi:foxo1_human(display_long)|uniprotkb:FOXO1(gene name)|psi-mi:FOXO1(display_short)|uniprotkb:FKHR(gene name synonym)|uniprotkb:FOXO1A(gene name synonym)|uniprotkb:Forkhead box protein O1A(gene name synonym)|uniprotkb:Forkhead in rhabdomyosarcoma(gene name synonym) psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:"MI:0096"(pull down) Chae et al. (2014) imex:IM-22928|pubmed:24983498 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9549144|imex:IM-22928-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000150907(gene)|ensembl:ENST00000379561(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097009"(energy homeostasis)|go:"GO:1902617"(response to fluoride)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032067|interpro:IPR032068|interpro:IPR036388|interpro:IPR036390|mint:Q12778|rcsb pdb:3CO6|rcsb pdb:3CO7|rcsb pdb:3COA|rcsb pdb:4LG0|rcsb pdb:5DUI|rcsb pdb:6LBI|rcsb pdb:6QVW|rcsb pdb:6QZR|rcsb pdb:6QZS|reactome:R-HSA-198693|reactome:R-HSA-210745|reactome:R-HSA-211163|reactome:R-HSA-5674400|reactome:R-HSA-5687128|reactome:R-HSA-6785807|reactome:R-HSA-9614399|reactome:R-HSA-9614657|reactome:R-HSA-9615017|reactome:R-HSA-9617629|reactome:R-HSA-9617828|refseq:NP_002006.2|dip:DIP-35654N refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) - - - figure legend:f2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/10 2014/10/16 rogid:oc4WR5KxeJntPcwhZU8zHFyTHCQ9606 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 intact-crc:48EB54884123B398|rigid:HhZB4C5ZpQz8WPhKF68Q/LcqvvY false flag tag:?-? binding-associated region:224-277|glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q12778 uniprotkb:Q01105 intact:EBI-1108782|uniprotkb:O43523|uniprotkb:Q5VYC7|uniprotkb:Q6NSK6|ensembl:ENSP00000368880 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 psi-mi:foxo1_human(display_long)|uniprotkb:FOXO1(gene name)|psi-mi:FOXO1(display_short)|uniprotkb:FKHR(gene name synonym)|uniprotkb:FOXO1A(gene name synonym)|uniprotkb:Forkhead box protein O1A(gene name synonym)|uniprotkb:Forkhead in rhabdomyosarcoma(gene name synonym) psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:"MI:0096"(pull down) Chae et al. (2014) imex:IM-22928|pubmed:24983498 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9549174|imex:IM-22928-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000150907(gene)|ensembl:ENST00000379561(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097009"(energy homeostasis)|go:"GO:1902617"(response to fluoride)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032067|interpro:IPR032068|interpro:IPR036388|interpro:IPR036390|mint:Q12778|rcsb pdb:3CO6|rcsb pdb:3CO7|rcsb pdb:3COA|rcsb pdb:4LG0|rcsb pdb:5DUI|rcsb pdb:6LBI|rcsb pdb:6QVW|rcsb pdb:6QZR|rcsb pdb:6QZS|reactome:R-HSA-198693|reactome:R-HSA-210745|reactome:R-HSA-211163|reactome:R-HSA-5674400|reactome:R-HSA-5687128|reactome:R-HSA-6785807|reactome:R-HSA-9614399|reactome:R-HSA-9614657|reactome:R-HSA-9615017|reactome:R-HSA-9617629|reactome:R-HSA-9617828|refseq:NP_002006.2|dip:DIP-35654N refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) - - - figure legend:f2c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/10 2014/10/16 rogid:oc4WR5KxeJntPcwhZU8zHFyTHCQ9606 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 intact-crc:BB8CCDD656DD1FB5|rigid:HhZB4C5ZpQz8WPhKF68Q/LcqvvY false glutathione s tranferase tag:?-?|binding-associated region:236-440 his tag:?-? - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q12778 uniprotkb:Q01105 intact:EBI-1108782|uniprotkb:O43523|uniprotkb:Q5VYC7|uniprotkb:Q6NSK6|ensembl:ENSP00000368880 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 psi-mi:foxo1_human(display_long)|uniprotkb:FOXO1(gene name)|psi-mi:FOXO1(display_short)|uniprotkb:FKHR(gene name synonym)|uniprotkb:FOXO1A(gene name synonym)|uniprotkb:Forkhead box protein O1A(gene name synonym)|uniprotkb:Forkhead in rhabdomyosarcoma(gene name synonym) psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chae et al. (2014) imex:IM-22928|pubmed:24983498 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9549162|imex:IM-22928-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000150907(gene)|ensembl:ENST00000379561(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097009"(energy homeostasis)|go:"GO:1902617"(response to fluoride)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032067|interpro:IPR032068|interpro:IPR036388|interpro:IPR036390|mint:Q12778|rcsb pdb:3CO6|rcsb pdb:3CO7|rcsb pdb:3COA|rcsb pdb:4LG0|rcsb pdb:5DUI|rcsb pdb:6LBI|rcsb pdb:6QVW|rcsb pdb:6QZR|rcsb pdb:6QZS|reactome:R-HSA-198693|reactome:R-HSA-210745|reactome:R-HSA-211163|reactome:R-HSA-5674400|reactome:R-HSA-5687128|reactome:R-HSA-6785807|reactome:R-HSA-9614399|reactome:R-HSA-9614657|reactome:R-HSA-9615017|reactome:R-HSA-9617629|reactome:R-HSA-9617828|refseq:NP_002006.2|dip:DIP-35654N refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) - - - figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/06/10 2014/10/16 rogid:oc4WR5KxeJntPcwhZU8zHFyTHCQ9606 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 intact-crc:B1BDC11FC1A9B66C|rigid:HhZB4C5ZpQz8WPhKF68Q/LcqvvY false - binding-associated region:224-277 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:Q12778 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1108782|uniprotkb:O43523|uniprotkb:Q5VYC7|uniprotkb:Q6NSK6|ensembl:ENSP00000368880 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:foxo1_human(display_long)|uniprotkb:FOXO1(gene name)|psi-mi:FOXO1(display_short)|uniprotkb:FKHR(gene name synonym)|uniprotkb:FOXO1A(gene name synonym)|uniprotkb:Forkhead box protein O1A(gene name synonym)|uniprotkb:Forkhead in rhabdomyosarcoma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chae et al. (2014) imex:IM-22928|pubmed:24983498 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9549194|imex:IM-22928-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) ensembl:ENSG00000150907(gene)|ensembl:ENST00000379561(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097009"(energy homeostasis)|go:"GO:1902617"(response to fluoride)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032067|interpro:IPR032068|interpro:IPR036388|interpro:IPR036390|mint:Q12778|rcsb pdb:3CO6|rcsb pdb:3CO7|rcsb pdb:3COA|rcsb pdb:4LG0|rcsb pdb:5DUI|rcsb pdb:6LBI|rcsb pdb:6QVW|rcsb pdb:6QZR|rcsb pdb:6QZS|reactome:R-HSA-198693|reactome:R-HSA-210745|reactome:R-HSA-211163|reactome:R-HSA-5674400|reactome:R-HSA-5687128|reactome:R-HSA-6785807|reactome:R-HSA-9614399|reactome:R-HSA-9614657|reactome:R-HSA-9615017|reactome:R-HSA-9617629|reactome:R-HSA-9617828|refseq:NP_002006.2|dip:DIP-35654N - - - figure legend:f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/06/10 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:oc4WR5KxeJntPcwhZU8zHFyTHCQ9606 intact-crc:65DC0AE2C4394A8C|rigid:HhZB4C5ZpQz8WPhKF68Q/LcqvvY false his tag:?-? binding-associated region:236-440|flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q12778 uniprotkb:Q01105 intact:EBI-1108782|uniprotkb:O43523|uniprotkb:Q5VYC7|uniprotkb:Q6NSK6|ensembl:ENSP00000368880 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 psi-mi:foxo1_human(display_long)|uniprotkb:FOXO1(gene name)|psi-mi:FOXO1(display_short)|uniprotkb:FKHR(gene name synonym)|uniprotkb:FOXO1A(gene name synonym)|uniprotkb:Forkhead box protein O1A(gene name synonym)|uniprotkb:Forkhead in rhabdomyosarcoma(gene name synonym) psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chae et al. (2014) imex:IM-22928|pubmed:24983498 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9549212|imex:IM-22928-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000150907(gene)|ensembl:ENST00000379561(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097009"(energy homeostasis)|go:"GO:1902617"(response to fluoride)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032067|interpro:IPR032068|interpro:IPR036388|interpro:IPR036390|mint:Q12778|rcsb pdb:3CO6|rcsb pdb:3CO7|rcsb pdb:3COA|rcsb pdb:4LG0|rcsb pdb:5DUI|rcsb pdb:6LBI|rcsb pdb:6QVW|rcsb pdb:6QZR|rcsb pdb:6QZS|reactome:R-HSA-198693|reactome:R-HSA-210745|reactome:R-HSA-211163|reactome:R-HSA-5674400|reactome:R-HSA-5687128|reactome:R-HSA-6785807|reactome:R-HSA-9614399|reactome:R-HSA-9614657|reactome:R-HSA-9615017|reactome:R-HSA-9617629|reactome:R-HSA-9617828|refseq:NP_002006.2|dip:DIP-35654N refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) - - - figure legend:f2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2014/06/10 2014/10/16 rogid:oc4WR5KxeJntPcwhZU8zHFyTHCQ9606 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 intact-crc:3E50280F8D753B2A|rigid:HhZB4C5ZpQz8WPhKF68Q/LcqvvY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)