#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B ensembl:ENSG00000012048 uniprotkb:Q9UGL1 intact:EBI-6141146 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 psi-mi:brca1_human_gene(display_short)|psi-mi:ENSG00000012048(display_long) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681446|imex:IM-22991-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:Supp Fig3A|comment:JARID1B and H3K4me2 have overlapping peaks in the promoter region. After JARID1B knockdown H3K4me2 levels increased.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2014/07/28 2014/10/16 - rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:E3038F025527D979 false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000079335 uniprotkb:Q9UGL1 intact:EBI-9681470 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 uniprotkb:CDC14A(gene name)|psi-mi:CDC14A(display_short)|intact:CDC14 cell division cycle 14 homolog A(synonym)|ensembl:cc14a_human_gene(shortlabel)|psi-mi:ENSG00000079335(display_long) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681464|imex:IM-22991-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:Supp Fig 3C|comment:JARID1B and H3K4me2 have overlapping peaks in the promoter region. After JARID1B knockdown H3K4me2 levels increased.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2014/07/28 2014/10/16 - rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:3CBD94F585BB6BBB false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q9UGL1 ensembl:ENSG00000154342 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-9681482 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) uniprotkb:WNT3A(gene name)|psi-mi:WNT3A(display_short)|ensembl:wnt3a_human_gene(shortlabel)|psi-mi:ENSG00000154342(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681475|imex:IM-22991-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - - figure legend:Supp Fig 3Ci|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2014/07/28 2014/10/16 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 - intact-crc:992E3B2C83C73DF6 false - sufficient binding region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000092969 uniprotkb:Q9UGL1 intact:EBI-9681034 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 uniprotkb:TGFB2(gene name)|psi-mi:TGFB2(display_short)|intact:BSC-1 cell growth inhibitor(synonym)|intact:Cetermin(synonym)|intact:Glioblastoma-derived T-cell suppressor factor(synonym)|intact:Polyergin(synonym)|ensembl:tgfb2_human_gene(shortlabel)|psi-mi:ENSG00000092969(display_long) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681031|imex:IM-22991-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:3F/Gi|comment:JARID1B and H3K4me3/me2 have overlapping peaks in the promoter region. After JARID1B knockdown H3K4me3/me2 levels increased.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2014/07/28 2014/10/16 - rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:B98D342B0ED28472 false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q9UGL1 ensembl:ENSG00000163347 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-9681074 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) uniprotkb:CLDN1(gene name)|psi-mi:CLDN1(display_short)|uniprotkb:CLD1(gene name synonym)|uniprotkb:SEMP1(gene name synonym)|intact:Senescence-associated epithelial membrane protein(synonym)|ensembl:cld1_human_gene(shortlabel)|psi-mi:ENSG00000163347(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681063|imex:IM-22991-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - - figure legend:3F/Giv|comment:JARID1B and H3K4me3/me2 have overlapping peaks in the promoter region. After JARID1B knockdown H3K4me3/me2 levels increased.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2014/07/28 2014/10/16 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 - intact-crc:981CD778DE92C5E9 false - sufficient binding region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q9UGL1 ensembl:ENSG00000118523 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-9253978 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:ctgf_human_gene(display_short)|psi-mi:ENSG00000118523(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681056|imex:IM-22991-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - - figure legend:3F/Giii|comment:JARID1B and H3K4me3/me2 have overlapping peaks in the promoter region. After JARID1B knockdown H3K4me3/me2 levels increased.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2014/07/28 2014/10/16 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 - intact-crc:28C1C46B77E40C89 false - sufficient binding region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000134363 uniprotkb:Q9UGL1 intact:EBI-9681052 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 uniprotkb:FST(gene name)|psi-mi:FST(display_short)|intact:Activin-binding protein(synonym)|ensembl:fst_human_gene(shortlabel)|psi-mi:ENSG00000134363(display_long) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681045|imex:IM-22991-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:3F/Gii|comment:JARID1B and H3K4me3/me2 have overlapping peaks in the promoter region. After JARID1B knockdown H3K4me3 levels increased.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2014/07/28 2014/10/16 - rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:BE1F9D0ECDFBF0F7 false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000105974 uniprotkb:Q9UGL1 intact:EBI-9681460 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)|uniprotkb:CAV(gene name synonym)|ensembl:cav1_human_gene(shortlabel)|psi-mi:ENSG00000105974(display_long) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681453|imex:IM-22991-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:Supp Fig3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2014/07/28 2014/10/16 - rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:9197F780938FC37E false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q9UGL1 uniprotkb:P49711 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681150|imex:IM-22991-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) - - - figure legend:6D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sum52pe)|taxid:9606(Human SUM52PE - pleural effusion of a metastatic breast carcinoma, triple negative) - 2014/07/28 2014/10/16 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 intact-crc:B731BEFAF18960D7|rigid:/CD4ccH5ltLaS66OI/Erw7stYNA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49711 uniprotkb:Q9UGL1 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681167|imex:IM-22991-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:6D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcc2157)|taxid:9606(Human HCC2157 primary ductal carcinoma, Pr+,ERBB2+,ER-) - 2014/07/28 2014/10/16 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:4F2EA21FDA03FC6A|rigid:/CD4ccH5ltLaS66OI/Erw7stYNA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49711 uniprotkb:Q9UGL1 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681133|imex:IM-22991-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:6D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sum159pt)|taxid:9606(Human SUM-159PT Anaplastic carcinoma, triple-negative) - 2014/07/28 2014/10/16 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:C21AEC4FDADB0A13|rigid:/CD4ccH5ltLaS66OI/Erw7stYNA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49711 uniprotkb:Q9UGL1 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681115|imex:IM-22991-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:6D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-cama-1)|taxid:9606("Human CAMA-1 Breast adenocarcinoma, derived from metastatic site: pleural effusion") - 2014/07/28 2014/10/16 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:E54AD0CA05D4F65A|rigid:/CD4ccH5ltLaS66OI/Erw7stYNA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49711 uniprotkb:Q9UGL1 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681091|imex:IM-22991-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:6D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2014/07/28 2014/10/16 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:AD4EAD6321B9F1B1|rigid:/CD4ccH5ltLaS66OI/Erw7stYNA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49711 uniprotkb:Q9UGL1 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681103|imex:IM-22991-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:6D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-t47d)|taxid:9606(human breast cancer tumour cell line-epithelial cells) - 2014/07/28 2014/10/16 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:290E4890089084F1|rigid:/CD4ccH5ltLaS66OI/Erw7stYNA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UGL1 ensembl:ENSG00000163435 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-9681353 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) uniprotkb:ELF3(gene name)|psi-mi:ELF3(display_short)|uniprotkb:ERT(gene name synonym)|uniprotkb:ESX(gene name synonym)|uniprotkb:JEN(gene name synonym)|intact:E74-like factor 3(synonym)|intact:Epithelial-restricted with serine box(synonym)|intact:Epithelium-restricted Ets protein ESX(synonym)|intact:Epithelium-specific Ets transcription factor 1(synonym)|ensembl:elf3_human_gene(shortlabel)|psi-mi:ENSG00000163435(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681343|imex:IM-22991-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - - figure legend:7D-8|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sum159pt)|taxid:9606(Human SUM-159PT Anaplastic carcinoma, triple-negative) - 2014/07/28 2014/10/16 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 - intact-crc:1726AACE459078C9 false his tag:n-n|mutation:1435-1435|myc tag:n-n - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q9UGL1 ensembl:ENSG00000178372 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-9681307 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) uniprotkb:CALML5(gene name)|psi-mi:CALML5(display_short)|uniprotkb:CLSP(gene name synonym)|intact:Calmodulin-like skin protein(synonym)|ensembl:call5_human_gene(shortlabel)|psi-mi:ENSG00000178372(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681297|imex:IM-22991-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - - figure legend:7D-5|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sum159pt)|taxid:9606(Human SUM-159PT Anaplastic carcinoma, triple-negative) - 2014/07/28 2014/10/16 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 - intact-crc:E695E9E380709275 false his tag:n-n|myc tag:n-n|mutation:1435-1435 - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000124212 uniprotkb:Q9UGL1 intact:EBI-9681281 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 uniprotkb:PTGIS(gene name)|psi-mi:PTGIS(display_short)|uniprotkb:CYP8(gene name synonym)|uniprotkb:CYP8A1(gene name synonym)|intact:Prostaglandin I2 synthase(synonym)|ensembl:ptgis_human_gene(shortlabel)|psi-mi:ENSG00000124212(display_long) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681271|imex:IM-22991-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:7D-3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sum159pt)|taxid:9606(Human SUM-159PT Anaplastic carcinoma, triple-negative) - 2014/07/28 2014/10/16 - rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:389394567E0901DF false - mutation:1435-1435|myc tag:n-n|his tag:n-n - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000198691 uniprotkb:Q9UGL1 intact:EBI-9681264 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 uniprotkb:ABCA4(gene name)|psi-mi:ABCA4(display_short)|uniprotkb:ABCR(gene name synonym)|intact:ATP-binding cassette sub-family A member 4(synonym)|intact:RIM ABC transporter(synonym)|intact:Stargardt disease protein(synonym)|ensembl:abca4_human_gene(shortlabel)|psi-mi:ENSG00000198691(display_long) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681254|imex:IM-22991-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:7D-2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sum159pt)|taxid:9606(Human SUM-159PT Anaplastic carcinoma, triple-negative) - 2014/07/28 2014/10/16 - rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:E691F9E380709275 false - myc tag:n-n|mutation:1435-1435|his tag:n-n - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q9UGL1 ensembl:ENSG00000122863 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-9681247 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) uniprotkb:CHST3(gene name)|psi-mi:CHST3(display_short)|intact:Chondroitin 6-O-sulfotransferase 1(synonym)|intact:Chondroitin 6-sulfotransferase(synonym)|intact:Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0(synonym)|ensembl:chst3_human_gene(shortlabel)|psi-mi:ENSG00000122863(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681287|imex:IM-22991-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - - figure legend:7D-4|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sum159pt)|taxid:9606(Human SUM-159PT Anaplastic carcinoma, triple-negative) - 2014/07/28 2014/10/16 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 - intact-crc:4DBE35E363A7B849 false mutation:1435-1435|myc tag:n-n|his tag:n-n - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q9UGL1 ensembl:ENSG00000107719 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-9681324 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) uniprotkb:PALD1(gene name)|psi-mi:PALD1(display_short)|uniprotkb:KIAA1274(gene name synonym)|uniprotkb:PALD(gene name synonym)|ensembl:pald_human_gene(shortlabel)|psi-mi:ENSG00000107719(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681312|imex:IM-22991-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - - figure legend:7D-6|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sum159pt)|taxid:9606(Human SUM-159PT Anaplastic carcinoma, triple-negative) - 2014/07/28 2014/10/16 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 - intact-crc:E69739E380709275 false mutation:1435-1435|his tag:n-n|myc tag:n-n - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q9UGL1 ensembl:ENSG00000104413 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-9681404 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) uniprotkb:ESRP1(gene name)|psi-mi:ESRP1(display_short)|uniprotkb:RBM35A(gene name synonym)|intact:RNA-binding motif protein 35A(synonym)|intact:RNA-binding protein 35A(synonym)|ensembl:esrp1_human_gene(shortlabel)|psi-mi:ENSG00000104413(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681394|imex:IM-22991-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - - figure legend:7D-12|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sum159pt)|taxid:9606(Human SUM-159PT Anaplastic carcinoma, triple-negative) - 2014/07/28 2014/10/16 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 - intact-crc:C3048458B65456A0 false myc tag:n-n|his tag:n-n|mutation:1435-1435 - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000124664 uniprotkb:Q9UGL1 intact:EBI-9681387 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 uniprotkb:SPDEF(gene name)|psi-mi:SPDEF(display_short)|uniprotkb:PDEF(gene name synonym)|uniprotkb:PSE(gene name synonym)|intact:Prostate epithelium-specific Ets transcription factor(synonym)|intact:Prostate-derived Ets factor(synonym)|ensembl:spdef_human_gene(shortlabel)|psi-mi:ENSG00000124664(display_long) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681377|imex:IM-22991-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:7D-11|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sum159pt)|taxid:9606(Human SUM-159PT Anaplastic carcinoma, triple-negative) - 2014/07/28 2014/10/16 - rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:DCAFDFE3584FB851 false - mutation:1435-1435|his tag:n-n|myc tag:n-n - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q9UGL1 ensembl:ENSG00000148719 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-9681374 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) uniprotkb:DNAJB12(gene name)|psi-mi:DNAJB12(display_short)|ensembl:djb12_human_gene(shortlabel)|psi-mi:ENSG00000148719(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681364|imex:IM-22991-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - - figure legend:7D-10|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sum159pt)|taxid:9606(Human SUM-159PT Anaplastic carcinoma, triple-negative) - 2014/07/28 2014/10/16 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 - intact-crc:602AFBF3FCBF1FDD false myc tag:n-n|his tag:n-n|mutation:1435-1435 - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000169067 uniprotkb:Q9UGL1 intact:EBI-9681339 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 uniprotkb:ACTBL2(gene name)|psi-mi:ACTBL2(display_short)|intact:Kappa-actin(synonym)|ensembl:actbl_human_gene(shortlabel)|psi-mi:ENSG00000169067(display_long) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681329|imex:IM-22991-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:7D-7|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sum159pt)|taxid:9606(Human SUM-159PT Anaplastic carcinoma, triple-negative) - 2014/07/28 2014/10/16 - rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:2D6E9935FE46A69A false - myc tag:n-n|mutation:1435-1435|his tag:n-n - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000122863 uniprotkb:Q9UGL1 intact:EBI-9681247 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 uniprotkb:CHST3(gene name)|psi-mi:CHST3(display_short)|intact:Chondroitin 6-O-sulfotransferase 1(synonym)|intact:Chondroitin 6-sulfotransferase(synonym)|intact:Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0(synonym)|ensembl:chst3_human_gene(shortlabel)|psi-mi:ENSG00000122863(display_long) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681238|imex:IM-22991-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - - figure legend:7D-1|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sum159pt)|taxid:9606(Human SUM-159PT Anaplastic carcinoma, triple-negative) - 2014/07/28 2014/10/16 - rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 intact-crc:E69329E380709275 false - his tag:n-n|mutation:1435-1435|myc tag:n-n - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:Q9UGL1 uniprotkb:P49711 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681418|imex:IM-22991-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) - - - figure legend:7F|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sum159pt)|taxid:9606(Human SUM-159PT Anaplastic carcinoma, triple-negative) - 2014/07/28 2014/10/16 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 intact-crc:508E0D1D7582E0B1|rigid:/CD4ccH5ltLaS66OI/Erw7stYNA false myc tag:n-n|his tag:n-n|mutation decreasing interaction strength:1435-1435 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UGL1 uniprotkb:P49711 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yamamoto et al. (2014) pubmed:24937458|imex:IM-22991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9681436|imex:IM-22991-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) - - - figure legend:7F|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2014/07/28 2014/10/16 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 intact-crc:D1A1BB49D15939A8|rigid:/CD4ccH5ltLaS66OI/Erw7stYNA false myc tag:n-n|his tag:n-n|mutation decreasing interaction strength:1435-1435 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)