#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O75586	uniprotkb:Q9NVC6	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695183|imex:IM-23033-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	intact-crc:9681B370AF9E2B8A|rigid:58mYTiBcI6cHFGd19IseNW5/uKQ	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6P2C8	uniprotkb:Q9NVC6	intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym)	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695777|imex:IM-23033-82	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	intact-crc:DC52512311A4C75B|rigid:ZNh+0EZ3sTaXSBsE/dBMMqqCVso	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9CQI9	uniprotkb:Q9NVC6	intact:EBI-309220|ensembl:ENSMUSP00000042204	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695785|imex:IM-23033-83	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	intact-crc:664BD8B3ACBC6145|rigid:21E5/gNPC8DCfq19MsMWG9WDk5s	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15528	uniprotkb:Q9NVC6	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695769|imex:IM-23033-81	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	intact-crc:1671DE786136662D|rigid:GPhffPCR9iNeyD6ulFMESmtaa3o	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q9NVC6	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695745|imex:IM-23033-78	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	intact-crc:EF0E7EDDAD58A168|rigid:IYbNEyCliY6tQyUInsP8HV3o8uo	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NVC6	uniprotkb:O75586	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695737|imex:IM-23033-77	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	intact-crc:982270CF4DC7A61A|rigid:58mYTiBcI6cHFGd19IseNW5/uKQ	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NX70	uniprotkb:Q15528	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695721|imex:IM-23033-75	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	intact-crc:25D63E0222FA2761|rigid:ZYb0NrhClhSElCeb0pMYgJGH3DA	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15528	uniprotkb:Q9CQI9	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	intact:EBI-309220|ensembl:ENSMUSP00000042204	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695729|imex:IM-23033-76	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	intact-crc:DF49494831FBA53F|rigid:VPLLki08REtv/4qR2fpM+tEKmoU	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15528	uniprotkb:Q9H204	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695713|imex:IM-23033-74	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	intact-crc:2FC3A257EA8893AC|rigid:MFoTc817FuRVV5R2VqIja9Ez6f8	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15528	uniprotkb:Q6P2C8	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695704|imex:IM-23033-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606	intact-crc:B661621EDEB18C65|rigid:+BXoS3Bc3ZKjsdKZ3JUJiDO3a3Y	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15528	uniprotkb:Q8C1S0	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	intact:EBI-398761|uniprotkb:Q80XM2|uniprotkb:Q8R3G3|ensembl:ENSMUSP00000099705	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:med19_mouse(display_long)|uniprotkb:Med19(gene name)|psi-mi:Med19(display_short)|uniprotkb:Mediator complex subunit 19(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695696|imex:IM-23033-72	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_080161.1|ensembl:ENSMUSG00000027080(gene)|ensembl:ENSMUST00000102645(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|mint:Q8C1S0|rcsb pdb:6W1S	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	rogid:Ls3LbNaAY+ng8jRY5+wfzy6RLpQ10090	intact-crc:ABCBD5C1878B29C4|rigid:zLcHICZJeo2VtDTm3eiEhN4URfA	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q15528	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695664|imex:IM-23033-68	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	intact-crc:A9ADDFCCB3CBAADA|rigid:Id7C8JpFrLpv17hFp7JiSUc8nBM	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15528	uniprotkb:Q9BUE0	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695688|imex:IM-23033-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606	intact-crc:432BE167D491492D|rigid:4KQQ1/1mcFDGbCpdl+fqHTHhJzI	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D8C6	uniprotkb:Q9NVC6	intact:EBI-6260909|ensembl:ENSMUSP00000019067|uniprotkb:Q3V4D0	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	psi-mi:med11_mouse(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:Med11(gene name)|psi-mi:Med11(display_short)	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695753|imex:IM-23033-79	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000018923(gene)|ensembl:ENSMUST00000019067(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|interpro:IPR019404|mint:Q9D8C6|rcsb pdb:6W1S|refseq:NP_079673.2	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:GzL0hfZ1n8eanV99Mqb1JTL4OXI10090	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	intact-crc:102FD475FE9DAD0C|rigid:vdXXavjStSQOLDTvV6YCZcKPdz0	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NVC6	uniprotkb:Q9R0X0	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695761|imex:IM-23033-80	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090	intact-crc:3B3F0EADDA603A8E|rigid:jEt2ZoS6qFB53vo3ZHJDWlZeFHs	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D8C6	uniprotkb:Q15528	intact:EBI-6260909|ensembl:ENSMUSP00000019067|uniprotkb:Q3V4D0	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	psi-mi:med11_mouse(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:Med11(gene name)|psi-mi:Med11(display_short)	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695672|imex:IM-23033-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000018923(gene)|ensembl:ENSMUST00000019067(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|interpro:IPR019404|mint:Q9D8C6|rcsb pdb:6W1S|refseq:NP_079673.2	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:GzL0hfZ1n8eanV99Mqb1JTL4OXI10090	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	intact-crc:C8A862C956B62E0C|rigid:18hmQAYRwJuMm0RSIImaTeY5uLY	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NVC6	uniprotkb:Q15528	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695680|imex:IM-23033-70	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	intact-crc:6029A25265A06766|rigid:GPhffPCR9iNeyD6ulFMESmtaa3o	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D8C6	uniprotkb:Q9NX70	intact:EBI-6260909|ensembl:ENSMUSP00000019067|uniprotkb:Q3V4D0	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	psi-mi:med11_mouse(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:Med11(gene name)|psi-mi:Med11(display_short)	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695646|imex:IM-23033-66	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000018923(gene)|ensembl:ENSMUST00000019067(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|interpro:IPR019404|mint:Q9D8C6|rcsb pdb:6W1S|refseq:NP_079673.2	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:GzL0hfZ1n8eanV99Mqb1JTL4OXI10090	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	intact-crc:1127E7B467B6D291|rigid:ATbDfKHnE92h6VhvTaBpfRgiuOE	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D8C6	uniprotkb:Q9CQI9	intact:EBI-6260909|ensembl:ENSMUSP00000019067|uniprotkb:Q3V4D0	intact:EBI-309220|ensembl:ENSMUSP00000042204	psi-mi:med11_mouse(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:Med11(gene name)|psi-mi:Med11(display_short)	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695654|imex:IM-23033-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000018923(gene)|ensembl:ENSMUST00000019067(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|interpro:IPR019404|mint:Q9D8C6|rcsb pdb:6W1S|refseq:NP_079673.2	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:GzL0hfZ1n8eanV99Mqb1JTL4OXI10090	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	intact-crc:CECA18289FAA282F|rigid:v9SHdup5Oxu4sMLyJZDQNr3+N+0	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H204	uniprotkb:Q9D8C6	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	intact:EBI-6260909|ensembl:ENSMUSP00000019067|uniprotkb:Q3V4D0	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:med11_mouse(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:Med11(gene name)|psi-mi:Med11(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695638|imex:IM-23033-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	ensembl:ENSMUSG00000018923(gene)|ensembl:ENSMUST00000019067(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|interpro:IPR019404|mint:Q9D8C6|rcsb pdb:6W1S|refseq:NP_079673.2	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	rogid:GzL0hfZ1n8eanV99Mqb1JTL4OXI10090	intact-crc:95A859D02AC4E19E|rigid:u0qYuCTteTKCsxx/1vIi2a14oc4	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6P2C8	uniprotkb:Q9D8C6	intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035	intact:EBI-6260909|ensembl:ENSMUSP00000019067|uniprotkb:Q3V4D0	psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym)	psi-mi:med11_mouse(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:Med11(gene name)|psi-mi:Med11(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695630|imex:IM-23033-64	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	ensembl:ENSMUSG00000018923(gene)|ensembl:ENSMUST00000019067(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|interpro:IPR019404|mint:Q9D8C6|rcsb pdb:6W1S|refseq:NP_079673.2	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606	rogid:GzL0hfZ1n8eanV99Mqb1JTL4OXI10090	intact-crc:74D391B822B28E31|rigid:TTTNP7S0HzbXjG9jKNH8neFpCMI	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15528	uniprotkb:Q9D8C6	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	intact:EBI-6260909|ensembl:ENSMUSP00000019067|uniprotkb:Q3V4D0	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:med11_mouse(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:Med11(gene name)|psi-mi:Med11(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695621|imex:IM-23033-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	ensembl:ENSMUSG00000018923(gene)|ensembl:ENSMUST00000019067(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|interpro:IPR019404|mint:Q9D8C6|rcsb pdb:6W1S|refseq:NP_079673.2	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	rogid:GzL0hfZ1n8eanV99Mqb1JTL4OXI10090	intact-crc:BEF01EE352202F47|rigid:18hmQAYRwJuMm0RSIImaTeY5uLY	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D8C6	uniprotkb:Q9NVC6	intact:EBI-6260909|ensembl:ENSMUSP00000019067|uniprotkb:Q3V4D0	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	psi-mi:med11_mouse(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:Med11(gene name)|psi-mi:Med11(display_short)	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695613|imex:IM-23033-62	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000018923(gene)|ensembl:ENSMUST00000019067(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|interpro:IPR019404|mint:Q9D8C6|rcsb pdb:6W1S|refseq:NP_079673.2	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:GzL0hfZ1n8eanV99Mqb1JTL4OXI10090	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	intact-crc:6677A85FFA0BAC47|rigid:vdXXavjStSQOLDTvV6YCZcKPdz0	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9CQI9	uniprotkb:Q9R0X0	intact:EBI-309220|ensembl:ENSMUSP00000042204	intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695401|imex:IM-23033-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090	intact-crc:8E70F2DF7EA098B2|rigid:G3DBXYfGJfSEm/MAm8XX+I/gEfE	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9BUE0	uniprotkb:Q9R0X0	intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184	intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778	psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym)	psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695369|imex:IM-23033-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606	rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090	intact-crc:A5E521245DF4DDB3|rigid:Dz4Ki69YjTjOW/y9d4T7SdZAcp0	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q9H204	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695323|imex:IM-23033-50	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	intact-crc:D6BC02F226E654E9|rigid:yQK+hBNitdy5Kwi3NFqw3oaVMpY	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q15528	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695307|imex:IM-23033-48	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	intact-crc:DFF5A3E6B75DAB91|rigid:Id7C8JpFrLpv17hFp7JiSUc8nBM	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9R0X0	uniprotkb:O75586	intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695349|imex:IM-23033-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	intact-crc:70195AA39FDB5FED|rigid:aZfrxomt2vV/9fvOA3XR1fZOjJs	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q9R0X0	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695361|imex:IM-23033-54	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090	intact-crc:073554B17F44589F|rigid:9UKzshNGX1JMThf7U+IybD71bSs	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q9NVC6	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695288|imex:IM-23033-46	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	intact-crc:995602F7A9CEA023|rigid:IYbNEyCliY6tQyUInsP8HV3o8uo	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q9R0X0	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695296|imex:IM-23033-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090	intact-crc:7C598C95923062B0|rigid:9UKzshNGX1JMThf7U+IybD71bSs	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:O75586	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695280|imex:IM-23033-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	intact-crc:2E2BB4E81A4CB982|rigid:kz9Y1Ix3mzZJPXBmAb8TOJAzD48	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9CQI9	uniprotkb:Q9BUE0	intact:EBI-309220|ensembl:ENSMUSP00000042204	intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695272|imex:IM-23033-44	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606	intact-crc:45499B861D8D4F0E|rigid:3Of1gPBE+bgpdF4GKU6z4/wwni4	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H204	uniprotkb:Q6P2C8	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694612|imex:IM-23033-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606	intact-crc:93B851269E8C3391|rigid:2CWk0VOu4UhmPxEHhFkLJjHGBZw	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NVC6	uniprotkb:Q9BUE0	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695239|imex:IM-23033-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606	intact-crc:A349FD14C2156AD3|rigid:ok1t7vnksnHn2nojyRPfiCtnGp8	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9BUE0	uniprotkb:Q9NX70	intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym)	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695264|imex:IM-23033-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	intact-crc:7E79EB32CC246508|rigid:l0rfAxyoQFwetoyw02axSSs8Sb8	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75586	uniprotkb:Q9NX70	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695215|imex:IM-23033-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	intact-crc:B78544086ACB7308|rigid:q6oxJ5hG6t8m60PtX8S6YgtsLvc	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9BUE0	uniprotkb:Q9D8C6	intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184	intact:EBI-6260909|ensembl:ENSMUSP00000019067|uniprotkb:Q3V4D0	psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym)	psi-mi:med11_mouse(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:Med11(gene name)|psi-mi:Med11(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695231|imex:IM-23033-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	ensembl:ENSMUSG00000018923(gene)|ensembl:ENSMUST00000019067(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|interpro:IPR019404|mint:Q9D8C6|rcsb pdb:6W1S|refseq:NP_079673.2	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606	rogid:GzL0hfZ1n8eanV99Mqb1JTL4OXI10090	intact-crc:6B7BED6C07B7AB78|rigid:h36h+KaqHWMMR0u5ieCt5ON6fiQ	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75586	uniprotkb:Q6P2C8	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695207|imex:IM-23033-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606	intact-crc:10F003411C7D602B|rigid:D8xMYAied6+TuJDABXHF2YuG3j4	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9R0X0	uniprotkb:O75586	intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695199|imex:IM-23033-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	intact-crc:05765F2CD08E2DE2|rigid:aZfrxomt2vV/9fvOA3XR1fZOjJs	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:O75586	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695175|imex:IM-23033-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	intact-crc:F13F3C23E61422F5|rigid:kz9Y1Ix3mzZJPXBmAb8TOJAzD48	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q9D8C6	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-6260909|ensembl:ENSMUSP00000019067|uniprotkb:Q3V4D0	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med11_mouse(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:Med11(gene name)|psi-mi:Med11(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695423|imex:IM-23033-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	ensembl:ENSMUSG00000018923(gene)|ensembl:ENSMUST00000019067(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|interpro:IPR019404|mint:Q9D8C6|rcsb pdb:6W1S|refseq:NP_079673.2	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:GzL0hfZ1n8eanV99Mqb1JTL4OXI10090	intact-crc:478FBE469E4EE802|rigid:5sXGUwKNcO8J/J6A+fzRMsturAA	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75586	uniprotkb:Q9D8C6	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	intact:EBI-6260909|ensembl:ENSMUSP00000019067|uniprotkb:Q3V4D0	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:med11_mouse(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:Med11(gene name)|psi-mi:Med11(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695409|imex:IM-23033-60	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	ensembl:ENSMUSG00000018923(gene)|ensembl:ENSMUST00000019067(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|interpro:IPR019404|mint:Q9D8C6|rcsb pdb:6W1S|refseq:NP_079673.2	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	rogid:GzL0hfZ1n8eanV99Mqb1JTL4OXI10090	intact-crc:30A3B0547ED1EF70|rigid:VINL3c1lwC/Pt4m6kMJrdySJH/A	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q9CQI9	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-309220|ensembl:ENSMUSP00000042204	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695339|imex:IM-23033-52	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	intact-crc:67F7E41748CBE86E|rigid:pO/uZjA8yA4uwgqFg8Raxzde8w8	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q9NX70	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695331|imex:IM-23033-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	intact-crc:05A95F8E3C25CEB4|rigid:qce7bqRVfD57G2gjQprZfQYEl2I	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6P2C8	uniprotkb:Q9R0X0	intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035	intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778	psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym)	psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695385|imex:IM-23033-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606	rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090	intact-crc:34697B4FC3B83EAC|rigid:Rf2cfdgHxvYqbORDJbCI9kbWVYA	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q6P2C8	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695315|imex:IM-23033-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606	intact-crc:4F6AC2661B284F12|rigid:sqJQ2f3gBoSxs9bCxlCOAWRrW4I	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15528	uniprotkb:Q9R0X0	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695377|imex:IM-23033-56	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090	intact-crc:FE4AF414B32A9FDA|rigid:tENnecqJ0ssWUfcfAVBWo6lNqkM	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NX70	uniprotkb:Q9R0X0	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695393|imex:IM-23033-58	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090	intact-crc:0898EED799AC7BC2|rigid:WFztdbcdehJNruk8qK9IDiw5lyk	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15528	uniprotkb:Q6P2C8	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694716|imex:IM-23033-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606	intact-crc:3CBD652CD5776B91|rigid:+BXoS3Bc3ZKjsdKZ3JUJiDO3a3Y	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9BUE0	uniprotkb:Q15528	intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym)	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695255|imex:IM-23033-42	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	intact-crc:9224D60967567FAD|rigid:4KQQ1/1mcFDGbCpdl+fqHTHhJzI	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9BUE0	uniprotkb:Q9R0X0	intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184	intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778	psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym)	psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695247|imex:IM-23033-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606	rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090	intact-crc:0253E526E0FB9DFA|rigid:Dz4Ki69YjTjOW/y9d4T7SdZAcp0	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75586	uniprotkb:Q9CQI9	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	intact:EBI-309220|ensembl:ENSMUSP00000042204	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695223|imex:IM-23033-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	intact-crc:A1FFCFDDCDC30BD5|rigid:IUD80r3AH89XWokMKU3+Goquodo	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75586	uniprotkb:Q9BUE0	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695191|imex:IM-23033-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606	intact-crc:B8B96B0193228B8C|rigid:tiQ9qyNKiXi4yJ94CVFAW7PvtP8	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NX70	uniprotkb:Q9CQI9	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	intact:EBI-309220|ensembl:ENSMUSP00000042204	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695167|imex:IM-23033-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	intact-crc:529E4D811CF62881|rigid:7jl/1LGYCiT4eEq0cFphOvdbj8E	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H204	uniprotkb:Q9CQI9	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	intact:EBI-309220|ensembl:ENSMUSP00000042204	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695159|imex:IM-23033-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	intact-crc:9173ADFA9BB85042|rigid:Pa8esjT2qYRK4lnmAybmkqjT0Kg	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9CQI9	uniprotkb:Q6P2C8	intact:EBI-309220|ensembl:ENSMUSP00000042204	intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695151|imex:IM-23033-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606	intact-crc:6C43D169D6036BF9|rigid:YQUQDCmFWgev5jo95ncLchbqhIE	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15528	uniprotkb:Q9CQI9	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	intact:EBI-309220|ensembl:ENSMUSP00000042204	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695143|imex:IM-23033-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	intact-crc:3FEC03E4B8503C81|rigid:VPLLki08REtv/4qR2fpM+tEKmoU	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9CQI9	uniprotkb:Q9R0X0	intact:EBI-309220|ensembl:ENSMUSP00000042204	intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695130|imex:IM-23033-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090	intact-crc:3C7489A7D7A4AB78|rigid:G3DBXYfGJfSEm/MAm8XX+I/gEfE	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q9CQI9	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-309220|ensembl:ENSMUSP00000042204	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695122|imex:IM-23033-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	intact-crc:3F35D58FA2D65F90|rigid:pO/uZjA8yA4uwgqFg8Raxzde8w8	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6P2C8	uniprotkb:Q9R0X0	intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035	intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778	psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym)	psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694708|imex:IM-23033-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606	rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090	intact-crc:D90A1FC93F26F105|rigid:Rf2cfdgHxvYqbORDJbCI9kbWVYA	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NVC6	uniprotkb:Q6P2C8	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694700|imex:IM-23033-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606	intact-crc:FE23C57240FE2946|rigid:ZNh+0EZ3sTaXSBsE/dBMMqqCVso	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q6P2C8	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694692|imex:IM-23033-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606	intact-crc:861DAE7050D243BE|rigid:sqJQ2f3gBoSxs9bCxlCOAWRrW4I	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6P2C8	uniprotkb:O75586	intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym)	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694684|imex:IM-23033-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	intact-crc:8A0E2D52FCF9ED97|rigid:D8xMYAied6+TuJDABXHF2YuG3j4	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NX70	uniprotkb:Q9H204	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694668|imex:IM-23033-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	intact-crc:B23EDB5692A5284D|rigid:GRZXpD4kjNf/lPtVjwrG7F5YKtA	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NX70	uniprotkb:Q15528	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694660|imex:IM-23033-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	intact-crc:BBE7E0B152B6058C|rigid:ZYb0NrhClhSElCeb0pMYgJGH3DA	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NX70	uniprotkb:Q9R0X0	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694652|imex:IM-23033-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090	intact-crc:1DC717D0D5FE5BD3|rigid:WFztdbcdehJNruk8qK9IDiw5lyk	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9CQI9	uniprotkb:Q9NX70	intact:EBI-309220|ensembl:ENSMUSP00000042204	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694676|imex:IM-23033-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	intact-crc:0D36A452D4670889|rigid:7jl/1LGYCiT4eEq0cFphOvdbj8E	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q9NX70	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694636|imex:IM-23033-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	intact-crc:BB3E36DA4830669D|rigid:qce7bqRVfD57G2gjQprZfQYEl2I	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D8C6	uniprotkb:Q9NX70	intact:EBI-6260909|ensembl:ENSMUSP00000019067|uniprotkb:Q3V4D0	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	psi-mi:med11_mouse(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:Med11(gene name)|psi-mi:Med11(display_short)	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694644|imex:IM-23033-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000018923(gene)|ensembl:ENSMUST00000019067(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|interpro:IPR019404|mint:Q9D8C6|rcsb pdb:6W1S|refseq:NP_079673.2	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:GzL0hfZ1n8eanV99Mqb1JTL4OXI10090	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	intact-crc:5D23561997FB1F69|rigid:ATbDfKHnE92h6VhvTaBpfRgiuOE	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9CQI9	uniprotkb:Q9H204	intact:EBI-309220|ensembl:ENSMUSP00000042204	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694628|imex:IM-23033-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	intact-crc:CEDB44295329704A|rigid:Pa8esjT2qYRK4lnmAybmkqjT0Kg	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15528	uniprotkb:Q9H204	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694604|imex:IM-23033-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	intact-crc:780A00CAD5F87D4F|rigid:MFoTc817FuRVV5R2VqIja9Ez6f8	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8C1S0	uniprotkb:Q9H204	intact:EBI-398761|uniprotkb:Q80XM2|uniprotkb:Q8R3G3|ensembl:ENSMUSP00000099705	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	psi-mi:med19_mouse(display_long)|uniprotkb:Med19(gene name)|psi-mi:Med19(display_short)|uniprotkb:Mediator complex subunit 19(gene name synonym)	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694596|imex:IM-23033-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080161.1|ensembl:ENSMUSG00000027080(gene)|ensembl:ENSMUST00000102645(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|mint:Q8C1S0|rcsb pdb:6W1S	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Ls3LbNaAY+ng8jRY5+wfzy6RLpQ10090	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	intact-crc:206FC53002E1BF27|rigid:29oiKUPf0th1uy63oSMLtkSV8qU	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NVC6	uniprotkb:Q9H204	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694588|imex:IM-23033-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	intact-crc:A4552C18EEBE53FF|rigid:IJEm4cXcsWR7lp5LDw+lTb/IhOE	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H204	uniprotkb:Q9D8C6	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	intact:EBI-6260909|ensembl:ENSMUSP00000019067|uniprotkb:Q3V4D0	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:med11_mouse(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:Med11(gene name)|psi-mi:Med11(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694580|imex:IM-23033-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	ensembl:ENSMUSG00000018923(gene)|ensembl:ENSMUST00000019067(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|interpro:IPR019404|mint:Q9D8C6|rcsb pdb:6W1S|refseq:NP_079673.2	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	rogid:GzL0hfZ1n8eanV99Mqb1JTL4OXI10090	intact-crc:35FEB04E29F9DBC4|rigid:u0qYuCTteTKCsxx/1vIi2a14oc4	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q9H204	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694572|imex:IM-23033-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	intact-crc:78D3D6A1CF7E1E5E|rigid:yQK+hBNitdy5Kwi3NFqw3oaVMpY	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NX70	uniprotkb:Q9H204	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694620|imex:IM-23033-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	intact-crc:ED9632855A340845|rigid:GRZXpD4kjNf/lPtVjwrG7F5YKtA	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H204	uniprotkb:O75586	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694564|imex:IM-23033-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	-	-	-	figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	intact-crc:7AC0134262ED6EFA|rigid:6nhubfdJiQxIk2dQ6r+ADoW7uBQ	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8C1S0	uniprotkb:O95402	intact:EBI-398761|uniprotkb:Q80XM2|uniprotkb:Q8R3G3|ensembl:ENSMUSP00000099705	intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390	psi-mi:med19_mouse(display_long)|uniprotkb:Med19(gene name)|psi-mi:Med19(display_short)|uniprotkb:Mediator complex subunit 19(gene name synonym)	psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695793|imex:IM-23033-84	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080161.1|ensembl:ENSMUSG00000027080(gene)|ensembl:ENSMUST00000102645(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|mint:Q8C1S0|rcsb pdb:6W1S	ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N	-	-	-	figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Ls3LbNaAY+ng8jRY5+wfzy6RLpQ10090	rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606	intact-crc:B674645568A8643E|rigid:ghNGkim6illgxtzf5AYIq0p/B/M	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8C1S0	uniprotkb:O95402	intact:EBI-398761|uniprotkb:Q80XM2|uniprotkb:Q8R3G3|ensembl:ENSMUSP00000099705	intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390	psi-mi:med19_mouse(display_long)|uniprotkb:Med19(gene name)|psi-mi:Med19(display_short)|uniprotkb:Mediator complex subunit 19(gene name synonym)	psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695801|imex:IM-23033-85	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080161.1|ensembl:ENSMUSG00000027080(gene)|ensembl:ENSMUST00000102645(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|mint:Q8C1S0|rcsb pdb:6W1S	ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N	-	-	-	figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Ls3LbNaAY+ng8jRY5+wfzy6RLpQ10090	rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606	intact-crc:124BF2494159DC49|rigid:ghNGkim6illgxtzf5AYIq0p/B/M	false	myc tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9CXU1	uniprotkb:O95402	intact:EBI-309355|uniprotkb:Q9DAP5|ensembl:ENSMUSP00000021157	intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390	psi-mi:med31_mouse(display_long)|uniprotkb:Med31(gene name)|psi-mi:Med31(display_short)|uniprotkb:Soh1(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym)	psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695809|imex:IM-23033-86	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080344.2|ensembl:ENSMUSG00000020801(gene)|ensembl:ENSMUST00000021157(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:6W1S|reactome:R-MMU-212436	ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N	-	-	-	figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Wy6xli/o/1mNyYP86nqOcIqcRzI10090	rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606	intact-crc:086432F257A7F6D7|rigid:XfPhSjfh0HhQc/WxVdOKd9QsJI0	false	myc tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75586	uniprotkb:Q8C1S0	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	intact:EBI-398761|uniprotkb:Q80XM2|uniprotkb:Q8R3G3|ensembl:ENSMUSP00000099705	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:med19_mouse(display_long)|uniprotkb:Med19(gene name)|psi-mi:Med19(display_short)|uniprotkb:Mediator complex subunit 19(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695817|imex:IM-23033-87	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	refseq:NP_080161.1|ensembl:ENSMUSG00000027080(gene)|ensembl:ENSMUST00000102645(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|mint:Q8C1S0|rcsb pdb:6W1S	-	-	-	figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	rogid:Ls3LbNaAY+ng8jRY5+wfzy6RLpQ10090	intact-crc:7C3C4647E2415C53|rigid:jO9E8IJTfcWFmtIEe+9ynh+r6gU	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9D7W5	uniprotkb:Q8C1S0	intact:EBI-7990252|uniprotkb:Q9JJ84|uniprotkb:Q99LM4|uniprotkb:Q3UGB4|intact:MINT-4101718|ensembl:ENSMUSP00000019229	intact:EBI-398761|uniprotkb:Q80XM2|uniprotkb:Q8R3G3|ensembl:ENSMUSP00000099705	psi-mi:med8_mouse(display_long)|uniprotkb:Med8(gene name)|psi-mi:Med8(display_short)|uniprotkb:MNCb-2386(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:med19_mouse(display_long)|uniprotkb:Med19(gene name)|psi-mi:Med19(display_short)|uniprotkb:Mediator complex subunit 19(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695825|imex:IM-23033-88	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064384.2|refseq:NP_001277617.1|refseq:NP_776067.1|ensembl:ENSMUSG00000006392(gene)|ensembl:ENSMUST00000019229(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q9D7W5|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_080161.1|ensembl:ENSMUSG00000027080(gene)|ensembl:ENSMUST00000102645(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|mint:Q8C1S0|rcsb pdb:6W1S	-	comment:mint|function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins	-	figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Km4DYU1zcI78vZAQzsHFhFCJ63410090	rogid:Ls3LbNaAY+ng8jRY5+wfzy6RLpQ10090	intact-crc:21975966485F3656|rigid:WKbf2Jhg17QvsJc+sf5JhfFZncI	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8C1S0	uniprotkb:Q9BUE0	intact:EBI-398761|uniprotkb:Q80XM2|uniprotkb:Q8R3G3|ensembl:ENSMUSP00000099705	intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184	psi-mi:med19_mouse(display_long)|uniprotkb:Med19(gene name)|psi-mi:Med19(display_short)|uniprotkb:Mediator complex subunit 19(gene name synonym)	psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695833|imex:IM-23033-89	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080161.1|ensembl:ENSMUSG00000027080(gene)|ensembl:ENSMUST00000102645(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|mint:Q8C1S0|rcsb pdb:6W1S	refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Ls3LbNaAY+ng8jRY5+wfzy6RLpQ10090	rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606	intact-crc:2F2A423A14DBF094|rigid:gxRDmMdLPNFAM3njpHQ0qu16rys	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NX70	uniprotkb:A0JLT2	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	intact:EBI-394430|uniprotkb:Q8IV02|intact:EBI-394763|uniprotkb:Q8IZD1	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:med19_human(display_long)|uniprotkb:MED19(gene name)|psi-mi:MED19(display_short)|uniprotkb:LCMR1(gene name synonym)|uniprotkb:Lung cancer metastasis-related protein 1(gene name synonym)|uniprotkb:Mediator complex subunit 19(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695841|imex:IM-23033-90	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_001304007.1|refseq:NP_703151.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|mint:A0JLT2|dip:DIP-31467N	-	-	-	figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	rogid:zcHhU2hQvuTpkFZz/xEKYmjrwOA9606	intact-crc:9AA71976F280779A|rigid:QSImgs8LcrIbU8x16i83DpZbSWw	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q13503	uniprotkb:Q15648	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892	intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695987|imex:IM-23033-95	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N	refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N	-	-	-	figure legend:Supp. Fig 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606	intact-crc:924112213A35CE03|rigid:SiCrqQPUUpFBFrD+wJwOwIakXRo	false	flag tag:?-?	sufficient binding region:1-597|myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NPJ6	uniprotkb:Q13503	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695997|imex:IM-23033-96	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N	-	-	-	figure legend:Supp. Fig 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	intact-crc:B2921C77694EAE36|rigid:jA8giq/FCkwcL6VC+VxtUyGZuqc	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O43513	uniprotkb:Q13503	intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892	psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym)	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696007|imex:IM-23033-97	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM	refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N	-	-	-	figure legend:Supp. Fig 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:K6K10aETITT6OIwedZj5qvG2OmI9606	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	intact-crc:C48BB00FE7F4D680|rigid:0OJJ/o02CjaVVUSo/zpwknIGhkU	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NWA0	uniprotkb:Q13503	intact:EBI-394653|ensembl:ENSP00000268711	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892	psi-mi:med9_human(display_long)|uniprotkb:MED9(gene name)|psi-mi:MED9(display_short)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:MED25(gene name synonym)	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696017|imex:IM-23033-98	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060489.1|ensembl:ENSG00000141026(gene)|ensembl:ENST00000268711(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|interpro:IPR037212|interpro:IPR039242|mint:Q9NWA0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N	-	-	-	figure legend:Supp. Fig 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:VSYpA1Aqh2FEaZIEF/6iCIpoPEc9606	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	intact-crc:058FEE61948CA8BC|rigid:bm8rW2vl7l03+ve7oNnWXjB9lKI	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NPJ6	uniprotkb:Q9NWA0	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	intact:EBI-394653|ensembl:ENSP00000268711	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:med9_human(display_long)|uniprotkb:MED9(gene name)|psi-mi:MED9(display_short)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:MED25(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696047|imex:IM-23033-101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	refseq:NP_060489.1|ensembl:ENSG00000141026(gene)|ensembl:ENST00000268711(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|interpro:IPR037212|interpro:IPR039242|mint:Q9NWA0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	rogid:VSYpA1Aqh2FEaZIEF/6iCIpoPEc9606	intact-crc:7C1B15E111AFACC4|rigid:oxlpbbteaBYfeZndPo+XnIZ7gkM	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O43513	uniprotkb:Q15648	intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046	intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651	psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym)	psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696027|imex:IM-23033-99	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM	refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N	-	-	-	figure legend:Supp. Fig 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:K6K10aETITT6OIwedZj5qvG2OmI9606	rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606	intact-crc:16C842A0FB11DE8E|rigid:EL84AyV44EHwuWssZ1WqYwukN1I	false	flag tag:?-?	myc tag:?-?|sufficient binding region:1-597	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9CXU0	uniprotkb:Q15648	intact:EBI-6260880|ensembl:ENSMUSP00000022089|uniprotkb:Q3U0W8|uniprotkb:Q80VV0	intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651	psi-mi:med10_mouse(display_long)|uniprotkb:D13Wsu50e(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Med10(gene name)|psi-mi:Med10(display_short)	psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695959|imex:IM-23033-92	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000021598(gene)|ensembl:ENSMUST00000022089(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019145|rcsb pdb:6W1S|reactome:R-MMU-212436|refseq:NP_613062.1	refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N	-	-	-	figure legend:Supp. Fig 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:AfEfa2zgRYMoqr1jicnJD314Pas10090	rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606	intact-crc:5CFA635796F5F786|rigid:NkU6t3nLyCS3kuptY5+uzPKs9bE	false	flag tag:?-?	sufficient binding region:1-597|myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15648	uniprotkb:O43513	intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651	intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046	psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym)	psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695859|imex:IM-23033-91	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N	refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM	-	-	-	figure legend:Supp. Fig 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606	rogid:K6K10aETITT6OIwedZj5qvG2OmI9606	intact-crc:7C7EE3C7C984F72E|rigid:EL84AyV44EHwuWssZ1WqYwukN1I	false	flag tag:?-?|sufficient binding region:1-597	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O43513	uniprotkb:Q9BTT4	intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym)	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695969|imex:IM-23033-93	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	-	-	-	figure legend:Supp. Fig 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:K6K10aETITT6OIwedZj5qvG2OmI9606	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	intact-crc:3DA46FA8A9BB5421|rigid:DSqdou6bdj4kXJr2tbRWeu8zdWg	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9CXU1	uniprotkb:O43513	intact:EBI-309355|uniprotkb:Q9DAP5|ensembl:ENSMUSP00000021157	intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046	psi-mi:med31_mouse(display_long)|uniprotkb:Med31(gene name)|psi-mi:Med31(display_short)|uniprotkb:Soh1(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym)	psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696037|imex:IM-23033-100	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080344.2|ensembl:ENSMUSG00000020801(gene)|ensembl:ENSMUST00000021157(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:6W1S|reactome:R-MMU-212436	refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM	-	-	-	figure legend:Supp. Fig 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Wy6xli/o/1mNyYP86nqOcIqcRzI10090	rogid:K6K10aETITT6OIwedZj5qvG2OmI9606	intact-crc:BAF72C7CA0865E1A|rigid:I1zKKiCQE9Hb5v4swNdCtxfTaf8	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NPJ6	uniprotkb:Q9NWA0	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	intact:EBI-394653|ensembl:ENSP00000268711	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:med9_human(display_long)|uniprotkb:MED9(gene name)|psi-mi:MED9(display_short)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:MED25(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9695979|imex:IM-23033-94	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	refseq:NP_060489.1|ensembl:ENSG00000141026(gene)|ensembl:ENST00000268711(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|interpro:IPR037212|interpro:IPR039242|mint:Q9NWA0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	rogid:VSYpA1Aqh2FEaZIEF/6iCIpoPEc9606	intact-crc:287AB259CDC755DC|rigid:oxlpbbteaBYfeZndPo+XnIZ7gkM	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O60244	uniprotkb:Q9ULK4	intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720	intact:EBI-311161|uniprotkb:Q5JWT3|uniprotkb:Q5JWT4|uniprotkb:Q6P9H6|uniprotkb:O95403|uniprotkb:Q9H0J2|uniprotkb:Q9NTT9|uniprotkb:Q9NTU0|uniprotkb:Q9Y5P7|uniprotkb:Q9Y667|ensembl:ENSP00000357047|uniprotkb:B9TX55	psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym)	psi-mi:med23_human(display_long)|uniprotkb:MED23(gene name)|psi-mi:MED23(display_short)|uniprotkb:ARC130(gene name synonym)|uniprotkb:DRIP130(gene name synonym)|uniprotkb:KIAA1216(gene name synonym)|uniprotkb:SUR2(gene name synonym)|uniprotkb:CRSP3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP130(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 130 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 130 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696107|imex:IM-23033-107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N	refseq:NP_057063.2|refseq:NP_004821.2|ensembl:ENSG00000112282(gene)|ensembl:ENST00000368068(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|interpro:IPR021629|mint:Q9ULK4|rcsb pdb:6H02|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001257450.1|refseq:NP_001257451.1|dip:DIP-31461N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606	rogid:gO5TvUnko3zY/83OHbeVmh7b+f89606	intact-crc:FAF37A7EF4C1C0E5|rigid:U1aTIIW9fK8AS7O9fdOI6mpkPus	false	flag tag:c-c	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75448	uniprotkb:Q9Y2X0	intact:EBI-394523|uniprotkb:Q14143|uniprotkb:Q9NNY5|uniprotkb:A8K4S5|uniprotkb:B3KMR9|ensembl:ENSP00000377686	intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612	psi-mi:med24_human(display_long)|uniprotkb:TRAP100(gene name synonym)|uniprotkb:MED24(gene name)|psi-mi:MED24(display_short)|uniprotkb:DRIP100(gene name synonym)|uniprotkb:KIAA0130(gene name synonym)|uniprotkb:Mediator complex subunit 24(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 100 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 100 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 100 kDa component(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 4(gene name synonym)|uniprotkb:ARC100(gene name synonym)|uniprotkb:CRSP4(gene name synonym)|uniprotkb:THRAP4(gene name synonym)	psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696147|imex:IM-23033-112	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016880955.1|refseq:NP_001072986.1|refseq:NP_055630.2|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021429|mint:O75448|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000008838(gene)|ensembl:ENST00000394128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|refseq:NP_001254726.1|dip:DIP-31462N	refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:H0iGOXcj8Qe1FOU7pOXkhaAS+pc9606	rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606	intact-crc:B4A9D2CEC4905756|rigid:+DH/TycE6bq63YjMSADvkYFcV7M	false	ha tag:?-?	t7 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96RN5	uniprotkb:Q71SY5	intact:EBI-394506|uniprotkb:O15413|uniprotkb:Q6IC31|uniprotkb:Q8NF16|uniprotkb:Q96CT0|uniprotkb:Q96IH7|uniprotkb:Q9P1T3|uniprotkb:D3DX31|uniprotkb:D3DX32|ensembl:ENSP00000263205	intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767	psi-mi:med15_human(display_long)|uniprotkb:MED15(gene name)|psi-mi:MED15(display_short)|uniprotkb:ARC105(gene name synonym)|uniprotkb:CTG7A(gene name synonym)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Positive cofactor 2 glutamine/Q-rich-associated protein(gene name synonym)|uniprotkb:TPA-inducible gene 1 protein(gene name synonym)|uniprotkb:Activator-recruited cofactor 105 kDa component(gene name synonym)|uniprotkb:CTG repeat protein 7a(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 7 protein(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:PCQAP(gene name synonym)|uniprotkb:TNRC7(gene name synonym)	psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696139|imex:IM-23033-111	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001280164.1|refseq:NP_001280165.1|refseq:NP_001003891.1|refseq:NP_056973.2|ensembl:ENSG00000099917(gene)|ensembl:ENST00000263205(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|interpro:IPR019087|interpro:IPR036529|mint:Q96RN5|rcsb pdb:2GUT|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-32908N	refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:8dqqSCXYc7Bp56sjogz0jpbTQLI9606	rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606	intact-crc:178D0AF9058392CE|rigid:rakZwiAh8TA0O9P2HPbdQdIGrpA	false	v5 tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O60244	uniprotkb:Q9ULK4	intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720	intact:EBI-311161|uniprotkb:Q5JWT3|uniprotkb:Q5JWT4|uniprotkb:Q6P9H6|uniprotkb:O95403|uniprotkb:Q9H0J2|uniprotkb:Q9NTT9|uniprotkb:Q9NTU0|uniprotkb:Q9Y5P7|uniprotkb:Q9Y667|ensembl:ENSP00000357047|uniprotkb:B9TX55	psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym)	psi-mi:med23_human(display_long)|uniprotkb:MED23(gene name)|psi-mi:MED23(display_short)|uniprotkb:ARC130(gene name synonym)|uniprotkb:DRIP130(gene name synonym)|uniprotkb:KIAA1216(gene name synonym)|uniprotkb:SUR2(gene name synonym)|uniprotkb:CRSP3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP130(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 130 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 130 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696083|imex:IM-23033-104	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N	refseq:NP_057063.2|refseq:NP_004821.2|ensembl:ENSG00000112282(gene)|ensembl:ENST00000368068(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|interpro:IPR021629|mint:Q9ULK4|rcsb pdb:6H02|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001257450.1|refseq:NP_001257451.1|dip:DIP-31461N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606	rogid:gO5TvUnko3zY/83OHbeVmh7b+f89606	intact-crc:CA481F2E25FEDE45|rigid:U1aTIIW9fK8AS7O9fdOI6mpkPus	false	flag tag:c-c	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75448	uniprotkb:O60244	intact:EBI-394523|uniprotkb:Q14143|uniprotkb:Q9NNY5|uniprotkb:A8K4S5|uniprotkb:B3KMR9|ensembl:ENSP00000377686	intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720	psi-mi:med24_human(display_long)|uniprotkb:TRAP100(gene name synonym)|uniprotkb:MED24(gene name)|psi-mi:MED24(display_short)|uniprotkb:DRIP100(gene name synonym)|uniprotkb:KIAA0130(gene name synonym)|uniprotkb:Mediator complex subunit 24(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 100 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 100 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 100 kDa component(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 4(gene name synonym)|uniprotkb:ARC100(gene name synonym)|uniprotkb:CRSP4(gene name synonym)|uniprotkb:THRAP4(gene name synonym)	psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696091|imex:IM-23033-105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016880955.1|refseq:NP_001072986.1|refseq:NP_055630.2|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021429|mint:O75448|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000008838(gene)|ensembl:ENST00000394128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|refseq:NP_001254726.1|dip:DIP-31462N	refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:H0iGOXcj8Qe1FOU7pOXkhaAS+pc9606	rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606	intact-crc:CB1DCD6911AADF2C|rigid:aarseHRL0h5TBsRhK3hc3YWAjh0	false	ha tag:?-?	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O60244	uniprotkb:Q96RN5	intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720	intact:EBI-394506|uniprotkb:O15413|uniprotkb:Q6IC31|uniprotkb:Q8NF16|uniprotkb:Q96CT0|uniprotkb:Q96IH7|uniprotkb:Q9P1T3|uniprotkb:D3DX31|uniprotkb:D3DX32|ensembl:ENSP00000263205	psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym)	psi-mi:med15_human(display_long)|uniprotkb:MED15(gene name)|psi-mi:MED15(display_short)|uniprotkb:ARC105(gene name synonym)|uniprotkb:CTG7A(gene name synonym)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Positive cofactor 2 glutamine/Q-rich-associated protein(gene name synonym)|uniprotkb:TPA-inducible gene 1 protein(gene name synonym)|uniprotkb:Activator-recruited cofactor 105 kDa component(gene name synonym)|uniprotkb:CTG repeat protein 7a(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 7 protein(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:PCQAP(gene name synonym)|uniprotkb:TNRC7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696057|imex:IM-23033-102	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N	refseq:NP_001280164.1|refseq:NP_001280165.1|refseq:NP_001003891.1|refseq:NP_056973.2|ensembl:ENSG00000099917(gene)|ensembl:ENST00000263205(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|interpro:IPR019087|interpro:IPR036529|mint:Q96RN5|rcsb pdb:2GUT|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-32908N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606	rogid:8dqqSCXYc7Bp56sjogz0jpbTQLI9606	intact-crc:F3B162544D5B4946|rigid:Hf3ngNRdhXQB4VPJsXYxmtmaJsA	false	flag tag:c-c	v5 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Y2X0	uniprotkb:O60244	intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612	intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720	psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)	psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696075|imex:IM-23033-103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N	refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606	rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606	intact-crc:60832BE1DCE40A46|rigid:EjRdDuDDYNcyWkGWJPgsfKJV9AU	false	t7 tag:?-?	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ULK4	uniprotkb:Q9Y2X0	intact:EBI-311161|uniprotkb:Q5JWT3|uniprotkb:Q5JWT4|uniprotkb:Q6P9H6|uniprotkb:O95403|uniprotkb:Q9H0J2|uniprotkb:Q9NTT9|uniprotkb:Q9NTU0|uniprotkb:Q9Y5P7|uniprotkb:Q9Y667|ensembl:ENSP00000357047|uniprotkb:B9TX55	intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612	psi-mi:med23_human(display_long)|uniprotkb:MED23(gene name)|psi-mi:MED23(display_short)|uniprotkb:ARC130(gene name synonym)|uniprotkb:DRIP130(gene name synonym)|uniprotkb:KIAA1216(gene name synonym)|uniprotkb:SUR2(gene name synonym)|uniprotkb:CRSP3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP130(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 130 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 130 kDa component(gene name synonym)	psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696115|imex:IM-23033-108	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057063.2|refseq:NP_004821.2|ensembl:ENSG00000112282(gene)|ensembl:ENST00000368068(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|interpro:IPR021629|mint:Q9ULK4|rcsb pdb:6H02|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001257450.1|refseq:NP_001257451.1|dip:DIP-31461N	refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:gO5TvUnko3zY/83OHbeVmh7b+f89606	rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606	intact-crc:DBD6446AD0CD43F6|rigid:2WqaUsP9LyV9p/9Xpqi9AMhyoTM	false	myc tag:?-?	t7 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q71SY5	uniprotkb:O60244	intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767	intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720	psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name)	psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696099|imex:IM-23033-106	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N	refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606	rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606	intact-crc:71BC6BFEBBFCAC90|rigid:O4iX6nsI/NAFElrLiaMxPFETOA0	false	tag:?-?	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q71SY5	uniprotkb:Q96RN5	intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767	intact:EBI-394506|uniprotkb:O15413|uniprotkb:Q6IC31|uniprotkb:Q8NF16|uniprotkb:Q96CT0|uniprotkb:Q96IH7|uniprotkb:Q9P1T3|uniprotkb:D3DX31|uniprotkb:D3DX32|ensembl:ENSP00000263205	psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name)	psi-mi:med15_human(display_long)|uniprotkb:MED15(gene name)|psi-mi:MED15(display_short)|uniprotkb:ARC105(gene name synonym)|uniprotkb:CTG7A(gene name synonym)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Positive cofactor 2 glutamine/Q-rich-associated protein(gene name synonym)|uniprotkb:TPA-inducible gene 1 protein(gene name synonym)|uniprotkb:Activator-recruited cofactor 105 kDa component(gene name synonym)|uniprotkb:CTG repeat protein 7a(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 7 protein(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:PCQAP(gene name synonym)|uniprotkb:TNRC7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696211|imex:IM-23033-120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N	refseq:NP_001280164.1|refseq:NP_001280165.1|refseq:NP_001003891.1|refseq:NP_056973.2|ensembl:ENSG00000099917(gene)|ensembl:ENST00000263205(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|interpro:IPR019087|interpro:IPR036529|mint:Q96RN5|rcsb pdb:2GUT|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-32908N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606	rogid:8dqqSCXYc7Bp56sjogz0jpbTQLI9606	intact-crc:4243FB5686764948|rigid:rakZwiAh8TA0O9P2HPbdQdIGrpA	false	tag:?-?	v5 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q71SY5	uniprotkb:Q9Y2X0	intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767	intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612	psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name)	psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696203|imex:IM-23033-119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N	refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606	rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606	intact-crc:29DF5213245E8378|rigid:h0rZ9+7RBmecGsy8ShjGUqtrQvM	false	tag:?-?	t7 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q71SY5	uniprotkb:Q9Y2X0	intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767	intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612	psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name)	psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696195|imex:IM-23033-118	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N	refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606	rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606	intact-crc:39A5FA5BE1EABCEE|rigid:h0rZ9+7RBmecGsy8ShjGUqtrQvM	false	tag:?-?	t7 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75448	uniprotkb:Q9Y2X0	intact:EBI-394523|uniprotkb:Q14143|uniprotkb:Q9NNY5|uniprotkb:A8K4S5|uniprotkb:B3KMR9|ensembl:ENSP00000377686	intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612	psi-mi:med24_human(display_long)|uniprotkb:TRAP100(gene name synonym)|uniprotkb:MED24(gene name)|psi-mi:MED24(display_short)|uniprotkb:DRIP100(gene name synonym)|uniprotkb:KIAA0130(gene name synonym)|uniprotkb:Mediator complex subunit 24(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 100 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 100 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 100 kDa component(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 4(gene name synonym)|uniprotkb:ARC100(gene name synonym)|uniprotkb:CRSP4(gene name synonym)|uniprotkb:THRAP4(gene name synonym)	psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696187|imex:IM-23033-117	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016880955.1|refseq:NP_001072986.1|refseq:NP_055630.2|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021429|mint:O75448|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000008838(gene)|ensembl:ENST00000394128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|refseq:NP_001254726.1|dip:DIP-31462N	refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:H0iGOXcj8Qe1FOU7pOXkhaAS+pc9606	rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606	intact-crc:490D229B1A2F18B0|rigid:+DH/TycE6bq63YjMSADvkYFcV7M	false	ha tag:?-?	t7 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ULK4	uniprotkb:Q9Y2X0	intact:EBI-311161|uniprotkb:Q5JWT3|uniprotkb:Q5JWT4|uniprotkb:Q6P9H6|uniprotkb:O95403|uniprotkb:Q9H0J2|uniprotkb:Q9NTT9|uniprotkb:Q9NTU0|uniprotkb:Q9Y5P7|uniprotkb:Q9Y667|ensembl:ENSP00000357047|uniprotkb:B9TX55	intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612	psi-mi:med23_human(display_long)|uniprotkb:MED23(gene name)|psi-mi:MED23(display_short)|uniprotkb:ARC130(gene name synonym)|uniprotkb:DRIP130(gene name synonym)|uniprotkb:KIAA1216(gene name synonym)|uniprotkb:SUR2(gene name synonym)|uniprotkb:CRSP3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP130(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 130 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 130 kDa component(gene name synonym)	psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696179|imex:IM-23033-116	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057063.2|refseq:NP_004821.2|ensembl:ENSG00000112282(gene)|ensembl:ENST00000368068(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|interpro:IPR021629|mint:Q9ULK4|rcsb pdb:6H02|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001257450.1|refseq:NP_001257451.1|dip:DIP-31461N	refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:gO5TvUnko3zY/83OHbeVmh7b+f89606	rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606	intact-crc:5D50363B5838FF70|rigid:2WqaUsP9LyV9p/9Xpqi9AMhyoTM	false	myc tag:?-?	t7 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O60244	uniprotkb:Q9Y2X0	intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720	intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612	psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym)	psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696163|imex:IM-23033-114	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N	refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606	rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606	intact-crc:1729A44ECBF53887|rigid:EjRdDuDDYNcyWkGWJPgsfKJV9AU	false	flag tag:c-c	t7 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q71SY5	uniprotkb:O75448	intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767	intact:EBI-394523|uniprotkb:Q14143|uniprotkb:Q9NNY5|uniprotkb:A8K4S5|uniprotkb:B3KMR9|ensembl:ENSP00000377686	psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name)	psi-mi:med24_human(display_long)|uniprotkb:TRAP100(gene name synonym)|uniprotkb:MED24(gene name)|psi-mi:MED24(display_short)|uniprotkb:DRIP100(gene name synonym)|uniprotkb:KIAA0130(gene name synonym)|uniprotkb:Mediator complex subunit 24(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 100 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 100 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 100 kDa component(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 4(gene name synonym)|uniprotkb:ARC100(gene name synonym)|uniprotkb:CRSP4(gene name synonym)|uniprotkb:THRAP4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696155|imex:IM-23033-113	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N	refseq:XP_016880955.1|refseq:NP_001072986.1|refseq:NP_055630.2|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021429|mint:O75448|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000008838(gene)|ensembl:ENST00000394128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|refseq:NP_001254726.1|dip:DIP-31462N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606	rogid:H0iGOXcj8Qe1FOU7pOXkhaAS+pc9606	intact-crc:4D49D0B05EF95649|rigid:gZnGwOQGwBq8g/NbIhA31x+cYkw	false	tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96RN5	uniprotkb:O60244	intact:EBI-394506|uniprotkb:O15413|uniprotkb:Q6IC31|uniprotkb:Q8NF16|uniprotkb:Q96CT0|uniprotkb:Q96IH7|uniprotkb:Q9P1T3|uniprotkb:D3DX31|uniprotkb:D3DX32|ensembl:ENSP00000263205	intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720	psi-mi:med15_human(display_long)|uniprotkb:MED15(gene name)|psi-mi:MED15(display_short)|uniprotkb:ARC105(gene name synonym)|uniprotkb:CTG7A(gene name synonym)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Positive cofactor 2 glutamine/Q-rich-associated protein(gene name synonym)|uniprotkb:TPA-inducible gene 1 protein(gene name synonym)|uniprotkb:Activator-recruited cofactor 105 kDa component(gene name synonym)|uniprotkb:CTG repeat protein 7a(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 7 protein(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:PCQAP(gene name synonym)|uniprotkb:TNRC7(gene name synonym)	psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696131|imex:IM-23033-110	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001280164.1|refseq:NP_001280165.1|refseq:NP_001003891.1|refseq:NP_056973.2|ensembl:ENSG00000099917(gene)|ensembl:ENST00000263205(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|interpro:IPR019087|interpro:IPR036529|mint:Q96RN5|rcsb pdb:2GUT|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-32908N	refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:8dqqSCXYc7Bp56sjogz0jpbTQLI9606	rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606	intact-crc:A67F93FBCEAE92C0|rigid:Hf3ngNRdhXQB4VPJsXYxmtmaJsA	false	v5 tag:?-?	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Y2X0	uniprotkb:Q96RN5	intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612	intact:EBI-394506|uniprotkb:O15413|uniprotkb:Q6IC31|uniprotkb:Q8NF16|uniprotkb:Q96CT0|uniprotkb:Q96IH7|uniprotkb:Q9P1T3|uniprotkb:D3DX31|uniprotkb:D3DX32|ensembl:ENSP00000263205	psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)	psi-mi:med15_human(display_long)|uniprotkb:MED15(gene name)|psi-mi:MED15(display_short)|uniprotkb:ARC105(gene name synonym)|uniprotkb:CTG7A(gene name synonym)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Positive cofactor 2 glutamine/Q-rich-associated protein(gene name synonym)|uniprotkb:TPA-inducible gene 1 protein(gene name synonym)|uniprotkb:Activator-recruited cofactor 105 kDa component(gene name synonym)|uniprotkb:CTG repeat protein 7a(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 7 protein(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:PCQAP(gene name synonym)|uniprotkb:TNRC7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696171|imex:IM-23033-115	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N	refseq:NP_001280164.1|refseq:NP_001280165.1|refseq:NP_001003891.1|refseq:NP_056973.2|ensembl:ENSG00000099917(gene)|ensembl:ENST00000263205(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|interpro:IPR019087|interpro:IPR036529|mint:Q96RN5|rcsb pdb:2GUT|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-32908N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606	rogid:8dqqSCXYc7Bp56sjogz0jpbTQLI9606	intact-crc:CD04334DE9083AC8|rigid:oGdgTuyzJghHpgX4ZMhAZkixQ3U	false	t7 tag:?-?	v5 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ULK4	uniprotkb:Q71SY5	intact:EBI-311161|uniprotkb:Q5JWT3|uniprotkb:Q5JWT4|uniprotkb:Q6P9H6|uniprotkb:O95403|uniprotkb:Q9H0J2|uniprotkb:Q9NTT9|uniprotkb:Q9NTU0|uniprotkb:Q9Y5P7|uniprotkb:Q9Y667|ensembl:ENSP00000357047|uniprotkb:B9TX55	intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767	psi-mi:med23_human(display_long)|uniprotkb:MED23(gene name)|psi-mi:MED23(display_short)|uniprotkb:ARC130(gene name synonym)|uniprotkb:DRIP130(gene name synonym)|uniprotkb:KIAA1216(gene name synonym)|uniprotkb:SUR2(gene name synonym)|uniprotkb:CRSP3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP130(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 130 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 130 kDa component(gene name synonym)	psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9696123|imex:IM-23033-109	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057063.2|refseq:NP_004821.2|ensembl:ENSG00000112282(gene)|ensembl:ENST00000368068(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|interpro:IPR021629|mint:Q9ULK4|rcsb pdb:6H02|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001257450.1|refseq:NP_001257451.1|dip:DIP-31461N	refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:gO5TvUnko3zY/83OHbeVmh7b+f89606	rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606	intact-crc:4B01E37C3FECC0EB|rigid:iamPdSfvCdrWaEM8TlJOhi8AqJE	false	myc tag:?-?	tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O95402	uniprotkb:O43513	intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390	intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046	psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym)	psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844830|imex:IM-23033-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N	refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM	-	-	-	comment:myc-tagged MED4 and MED7 differentiated by molecular weight.|figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606	rogid:K6K10aETITT6OIwedZj5qvG2OmI9606	intact-crc:C416D72FE8C9D56C|rigid:D5VxPhU9tOtatYpRzw0hWEBPf84	false	flag tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O95402	uniprotkb:Q9NPJ6	intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844830|imex:IM-23033-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	comment:myc-tagged MED4 and MED7 differentiated by molecular weight.|figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:C416D72FE8C9D56C|rigid:D5VxPhU9tOtatYpRzw0hWEBPf84	false	flag tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O95402	uniprotkb:Q9NPJ6	intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844851|imex:IM-23033-122	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:075F02FE951FFBFD|rigid:1WCckGGMBDS8XHNu7lsSxlAEzuI	false	flag tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O95402	uniprotkb:O43513	intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390	intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046	psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym)	psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844869|imex:IM-23033-124	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N	refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM	-	-	-	comment:myc-tagged MED4 and MED7 differentiated by molecular weight.|figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606	rogid:K6K10aETITT6OIwedZj5qvG2OmI9606	intact-crc:A73A7D7B847D7232|rigid:ZOCikmvz/75Lh6YJ21dKhupg6Fs	false	flag tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O95402	uniprotkb:Q13503	intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892	psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym)	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844869|imex:IM-23033-124	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N	refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N	-	-	-	comment:myc-tagged MED4 and MED7 differentiated by molecular weight.|figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	intact-crc:A73A7D7B847D7232|rigid:ZOCikmvz/75Lh6YJ21dKhupg6Fs	false	flag tag:n-n	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O95402	uniprotkb:Q9NPJ6	intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844869|imex:IM-23033-124	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	comment:myc-tagged MED4 and MED7 differentiated by molecular weight.|figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:A73A7D7B847D7232|rigid:ZOCikmvz/75Lh6YJ21dKhupg6Fs	false	flag tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O95402	uniprotkb:O43513	intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390	intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046	psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym)	psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844860|imex:IM-23033-123	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N	refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM	-	-	-	figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606	rogid:K6K10aETITT6OIwedZj5qvG2OmI9606	intact-crc:098060C297617CA5|rigid:yRt81I4rnfkndPypXgGDGrPaAcs	false	flag tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15648	uniprotkb:O43513	intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651	intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046	psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym)	psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844900|imex:IM-23033-126	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N	refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM	-	-	-	figure legend:Supp. Fig 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606	rogid:K6K10aETITT6OIwedZj5qvG2OmI9606	intact-crc:3C7B7F325BD6F760|rigid:EL84AyV44EHwuWssZ1WqYwukN1I	false	flag tag:?-?|sufficient binding region:1-597	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15648	uniprotkb:O43513	intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651	intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046	psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym)	psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844884|imex:IM-23033-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N	refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM	-	-	-	figure legend:Supp. Fig 5B|comment:Myc tagged construct differentiated by molecular weight.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606	rogid:K6K10aETITT6OIwedZj5qvG2OmI9606	intact-crc:CC6AEA5585255F4D|rigid:PUrsbwwt3zaH0KuB2Lh6zu8FKoM	false	flag tag:?-?|sufficient binding region:1-597	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15648	uniprotkb:Q9NWA0	intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651	intact:EBI-394653|ensembl:ENSP00000268711	psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym)	psi-mi:med9_human(display_long)|uniprotkb:MED9(gene name)|psi-mi:MED9(display_short)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:MED25(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844884|imex:IM-23033-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N	refseq:NP_060489.1|ensembl:ENSG00000141026(gene)|ensembl:ENST00000268711(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|interpro:IPR037212|interpro:IPR039242|mint:Q9NWA0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5B|comment:Myc tagged construct differentiated by molecular weight.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606	rogid:VSYpA1Aqh2FEaZIEF/6iCIpoPEc9606	intact-crc:CC6AEA5585255F4D|rigid:PUrsbwwt3zaH0KuB2Lh6zu8FKoM	false	flag tag:?-?|sufficient binding region:1-597	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15648	uniprotkb:Q9NPJ6	intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844884|imex:IM-23033-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5B|comment:Myc tagged construct differentiated by molecular weight.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:CC6AEA5585255F4D|rigid:PUrsbwwt3zaH0KuB2Lh6zu8FKoM	false	flag tag:?-?|sufficient binding region:1-597	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15648	uniprotkb:Q9NPJ6	intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844910|imex:IM-23033-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5B|comment:Myc tagged construct differentiated by molecular weight.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:E8FF35721A97415B|rigid:6Jb7neTNtjBuaTK4djEfkl4Kl8E	false	flag tag:?-?|sufficient binding region:1-597	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15648	uniprotkb:Q9NWA0	intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651	intact:EBI-394653|ensembl:ENSP00000268711	psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym)	psi-mi:med9_human(display_long)|uniprotkb:MED9(gene name)|psi-mi:MED9(display_short)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:MED25(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844910|imex:IM-23033-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N	refseq:NP_060489.1|ensembl:ENSG00000141026(gene)|ensembl:ENST00000268711(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|interpro:IPR037212|interpro:IPR039242|mint:Q9NWA0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Supp. Fig 5B|comment:Myc tagged construct differentiated by molecular weight.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/08/27	2014/10/16	rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606	rogid:VSYpA1Aqh2FEaZIEF/6iCIpoPEc9606	intact-crc:E8FF35721A97415B|rigid:6Jb7neTNtjBuaTK4djEfkl4Kl8E	false	flag tag:?-?|sufficient binding region:1-597	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9BTT4	uniprotkb:Q9P086	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394704|uniprotkb:Q6NS89|ensembl:ENSP00000293777	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med11_human(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short)|uniprotkb:HSPC296(orf name)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_001291929.1|refseq:NP_001001683.1|ensembl:ENSG00000161920(gene)|ensembl:ENST00000293777(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019404|mint:Q9P086|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|go:"GO:0003712"(transcription coregulator activity)	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:y7SZi5hIo5aOatJSZi98Hqt082A9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:O60244	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q96RN5	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394506|uniprotkb:O15413|uniprotkb:Q6IC31|uniprotkb:Q8NF16|uniprotkb:Q96CT0|uniprotkb:Q96IH7|uniprotkb:Q9P1T3|uniprotkb:D3DX31|uniprotkb:D3DX32|ensembl:ENSP00000263205	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med15_human(display_long)|uniprotkb:MED15(gene name)|psi-mi:MED15(display_short)|uniprotkb:ARC105(gene name synonym)|uniprotkb:CTG7A(gene name synonym)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Positive cofactor 2 glutamine/Q-rich-associated protein(gene name synonym)|uniprotkb:TPA-inducible gene 1 protein(gene name synonym)|uniprotkb:Activator-recruited cofactor 105 kDa component(gene name synonym)|uniprotkb:CTG repeat protein 7a(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 7 protein(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:PCQAP(gene name synonym)|uniprotkb:TNRC7(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_001280164.1|refseq:NP_001280165.1|refseq:NP_001003891.1|refseq:NP_056973.2|ensembl:ENSG00000099917(gene)|ensembl:ENST00000263205(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|interpro:IPR019087|interpro:IPR036529|mint:Q96RN5|rcsb pdb:2GUT|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-32908N	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:8dqqSCXYc7Bp56sjogz0jpbTQLI9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q9Y2X0	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q9NVC6	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q9BUE0	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:A0JLT2	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394430|uniprotkb:Q8IV02|intact:EBI-394763|uniprotkb:Q8IZD1	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med19_human(display_long)|uniprotkb:MED19(gene name)|psi-mi:MED19(display_short)|uniprotkb:LCMR1(gene name synonym)|uniprotkb:Lung cancer metastasis-related protein 1(gene name synonym)|uniprotkb:Mediator complex subunit 19(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_001304007.1|refseq:NP_703151.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|mint:A0JLT2|dip:DIP-31467N	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:zcHhU2hQvuTpkFZz/xEKYmjrwOA9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q15648	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q9H944	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394644|uniprotkb:Q9Y429|uniprotkb:O95821|uniprotkb:Q5T8J4|uniprotkb:B4DE08|ensembl:ENSP00000265350	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med20_human(display_long)|uniprotkb:TRFP(gene name synonym)|uniprotkb:MED20(gene name)|psi-mi:MED20(display_short)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_004266.2|refseq:NP_001292384.1|refseq:NP_001292385.1|refseq:NP_001292386.1|go:"GO:0016592"(mediator complex)|interpro:IPR013921(TATA-binding related factor)|mint:Q9H944|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000124641(gene)|ensembl:ENST00000265350(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|dip:DIP-31449N	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:MpYOrONH6+0lKIlO6J+Szjzkw2A9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q13503	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q15528	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q9ULK4	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-311161|uniprotkb:Q5JWT3|uniprotkb:Q5JWT4|uniprotkb:Q6P9H6|uniprotkb:O95403|uniprotkb:Q9H0J2|uniprotkb:Q9NTT9|uniprotkb:Q9NTU0|uniprotkb:Q9Y5P7|uniprotkb:Q9Y667|ensembl:ENSP00000357047|uniprotkb:B9TX55	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med23_human(display_long)|uniprotkb:MED23(gene name)|psi-mi:MED23(display_short)|uniprotkb:ARC130(gene name synonym)|uniprotkb:DRIP130(gene name synonym)|uniprotkb:KIAA1216(gene name synonym)|uniprotkb:SUR2(gene name synonym)|uniprotkb:CRSP3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP130(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 130 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 130 kDa component(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_057063.2|refseq:NP_004821.2|ensembl:ENSG00000112282(gene)|ensembl:ENST00000368068(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|interpro:IPR021629|mint:Q9ULK4|rcsb pdb:6H02|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001257450.1|refseq:NP_001257451.1|dip:DIP-31461N	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:gO5TvUnko3zY/83OHbeVmh7b+f89606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:O75448	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394523|uniprotkb:Q14143|uniprotkb:Q9NNY5|uniprotkb:A8K4S5|uniprotkb:B3KMR9|ensembl:ENSP00000377686	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med24_human(display_long)|uniprotkb:TRAP100(gene name synonym)|uniprotkb:MED24(gene name)|psi-mi:MED24(display_short)|uniprotkb:DRIP100(gene name synonym)|uniprotkb:KIAA0130(gene name synonym)|uniprotkb:Mediator complex subunit 24(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 100 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 100 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 100 kDa component(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 4(gene name synonym)|uniprotkb:ARC100(gene name synonym)|uniprotkb:CRSP4(gene name synonym)|uniprotkb:THRAP4(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:XP_016880955.1|refseq:NP_001072986.1|refseq:NP_055630.2|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021429|mint:O75448|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000008838(gene)|ensembl:ENST00000394128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|refseq:NP_001254726.1|dip:DIP-31462N	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:H0iGOXcj8Qe1FOU7pOXkhaAS+pc9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q71SY5	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:O95402	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q6P2C8	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q9H204	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q9NX70	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q96HR3	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q9Y3C7	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q9NPJ6	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:O75586	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:O43513	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:K6K10aETITT6OIwedZj5qvG2OmI9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q96G25	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394405|uniprotkb:A9IZ91|uniprotkb:Q96FQ4|uniprotkb:A9IZ92|uniprotkb:Q5JUY8|ensembl:ENSP00000361535	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med8_human(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_443109.2|refseq:NP_963836.2|refseq:NP_001001653.1|ensembl:ENSG00000159479(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q96G25|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENST00000372457(transcript)	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:e/ye7rfa2E1XOPb5vVhI9Nvqmxw9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BTT4	uniprotkb:Q9NWA0	intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764	intact:EBI-394653|ensembl:ENSP00000268711	psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name)	psi-mi:med9_human(display_long)|uniprotkb:MED9(gene name)|psi-mi:MED9(display_short)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:MED25(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694525|emdb:EMD-2635|imex:IM-23033-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N	refseq:NP_060489.1|ensembl:ENSG00000141026(gene)|ensembl:ENST00000268711(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|interpro:IPR037212|interpro:IPR039242|mint:Q9NWA0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	3d-resolution:3nM|figure legend:Fig. 4|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - MED6, MED8, MED11, MED17, MED18, MED20, MED22, MED27, MED28, MED29, MED30  Middle - MED1, MED4, MED7, MED9, MED10, MED19, MED21, MED26, MED31  Tail - MED14, MED15, MED16, MED23, MED24, MED25,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/08/27	2014/10/16	rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606	rogid:VSYpA1Aqh2FEaZIEF/6iCIpoPEc9606	intact-crc:EC5612A68A8B88BA|rigid:eVn+4Lz/ZZgaIX72SpuPnqqtdmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32570	uniprotkb:P32259	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-17172|ensemblfungi:YNL236W|uniprotkb:D6W0V7	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med16_yeast(display_long)|uniprotkb:SIN4(gene name)|psi-mi:SIN4(display_short)|uniprotkb:BEL2(gene name synonym)|uniprotkb:GAL22(gene name synonym)|uniprotkb:SSF5(gene name synonym)|uniprotkb:YNL236W(locus name)|uniprotkb:N1135(orf name)|uniprotkb:TSF3(gene name synonym)|uniprotkb:MED16(gene name synonym)|uniprotkb:RYE1(gene name synonym)|uniprotkb:SDI3(gene name synonym)|uniprotkb:SSN4(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Global transcriptional regulator SIN4(gene name synonym)|uniprotkb:YGP1 expression regulatory protein 1(gene name synonym)|uniprotkb:Transcriptional silencing factor 3(gene name synonym)|uniprotkb:SWI4 suppressor protein 5(gene name synonym)|uniprotkb:SNF1 suppressor protein 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	refseq:NP_014163.1|sgd:S000005180|ensemblfungi:YNL236W(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070202"(regulation of establishment of protein localization to chromosome)|go:"GO:0070847"(core mediator complex)|interpro:IPR021665|ensemblfungi:YNL236W_mRNA(transcript)|dip:DIP-1617N|mint:P32259	-	crc64:7703E4FAE101A31F	crc64:12ECF5E4CDC05A8E	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:krTYeU9eXPNnPWcoz+idZe7fRIE559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:P19659	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-7305|uniprotkb:Q08221|uniprotkb:D6W217|ensemblfungi:YOL051W	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med15_yeast(display_long)|uniprotkb:YOL051W(locus name)|uniprotkb:GAL11(gene name)|psi-mi:GAL11(display_short)|uniprotkb:RAR3(gene name synonym)|uniprotkb:SPT13(gene name synonym)|uniprotkb:ABE1(gene name synonym)|uniprotkb:MED15(gene name synonym)|uniprotkb:SDS4(gene name synonym)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Transcription regulatory protein GAL11(gene name synonym)|uniprotkb:Basal expression activator protein 1(gene name synonym)|uniprotkb:Autonomous replication regulatory protein 3(gene name synonym)|uniprotkb:Defective silencing suppressor protein 4(gene name synonym)|uniprotkb:Ty insertion suppressor protein 13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	refseq:NP_014591.1|sgd:S000005411|mint:P19659|dip:DIP-2334N|ensemblfungi:YOL051W(gene)|ensemblfungi:YOL051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001095"(TFIIE-class transcription factor complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070202"(regulation of establishment of protein localization to chromosome)|go:"GO:0070847"(core mediator complex)|go:"GO:2000219"(positive regulation of invasive growth in response to glucose limitation)|interpro:IPR008626(GAL11 transcriptional regulator)|interpro:IPR033789|interpro:IPR036529|interpro:IPR036546|rcsb pdb:2K0N|rcsb pdb:2LPB|rcsb pdb:6ALY	-	crc64:7703E4FAE101A31F	crc64:275C78721B5415C7	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:wkvx9dInmIwvGKlHPvoOtY9QmAY559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:Q99278	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-27213|uniprotkb:D6VZT5	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA	-	crc64:7703E4FAE101A31F	crc64:457D13C6030F33CC	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:Q12343	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-31503|uniprotkb:D6W2N0|ensemblfungi:YOR174W	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med4_yeast(display_long)|uniprotkb:O3630(orf name)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:YOR174W(locus name)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	sgd:S000005700|refseq:NP_014817.3|dip:DIP-1178N|mint:Q12343|ensemblfungi:YOR174W(gene)|ensemblfungi:YOR174W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|rcsb pdb:5OQM|rcsb pdb:5SVA	-	crc64:7703E4FAE101A31F	crc64:D42A3C62D465DDAD	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:R+wCh3eGS74E+DEQm21XHMd59y0559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:P19263	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-15087|uniprotkb:Q07999|uniprotkb:D6VY72|ensemblfungi:YLR071C	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med14_yeast(display_long)|uniprotkb:RGR1(gene name)|psi-mi:RGR1(display_short)|uniprotkb:MED14(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Glucose repression regulatory protein 1(gene name synonym)|uniprotkb:YLR071C(locus name)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	refseq:NP_013172.1|sgd:S000004061|ensemblfungi:YLR071C(gene)|ensemblfungi:YLR071C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|rcsb pdb:5OQM|dip:DIP-1562N|mint:P19263	-	crc64:7703E4FAE101A31F	crc64:96277001829DB539	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:WbZxedNQBe+lFVW5hCxmuyAc4r8559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:P38782	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-10667|ensemblfungi:YHR058C|uniprotkb:D3DL07	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med6_yeast(display_long)|uniprotkb:MTR32(gene name synonym)|uniprotkb:YHR058C(locus name)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	refseq:NP_011925.1|sgd:S000001100|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016612(Mediator complex, subunit 6, fungi)|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YHR058C(gene)|ensemblfungi:YHR058C_mRNA(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|mint:P38782|dip:DIP-2093N	-	crc64:7703E4FAE101A31F	crc64:B84E87DCC2737849	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:XcKvvx/GJGRLZpv1MPzpPtVd2RI559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:P38633	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-17658|uniprotkb:D6VU21|ensemblfungi:YGL127C	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med31_yeast(display_long)|uniprotkb:SOH1(gene name)|psi-mi:SOH1(display_short)|uniprotkb:YGL127C(locus name)|uniprotkb:G2864(orf name)|uniprotkb:MED31(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Hpr1 suppressor protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	ensemblfungi:YGL127C(gene)|ensemblfungi:YGL127C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_011388.1|sgd:S000003095|dip:DIP-1179N|mint:P38633	-	crc64:7703E4FAE101A31F	-	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:7jJUtvDYjsYKT1AcECsAgyDmlPw559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:P53114	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-12407|ensemblfungi:YGL151W|uniprotkb:D6VTZ9	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med5_yeast(display_long)|uniprotkb:NUT1(gene name)|psi-mi:NUT1(display_short)|uniprotkb:YGL151W(locus name)|uniprotkb:G1876(orf name)|uniprotkb:MED5(gene name synonym)|uniprotkb:Mediator complex subunit 5(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	ensemblfungi:YGL151W(gene)|ensemblfungi:YGL151W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR014801(Mediator complex, subunit Med5)|refseq:NP_011364.1|sgd:S000003119|mint:P53114|dip:DIP-6632N	-	crc64:7703E4FAE101A31F	crc64:BBD54661A4DB5F09	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:PZX5GBu0/S00vR1eP3R7UYjX6Sk559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:P32585	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585	-	crc64:7703E4FAE101A31F	crc64:B1148FC187C2802A	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:+/qC0affGDlvusbTV43B3aCgZBU559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:P25046	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-15722|uniprotkb:D6VPR0|ensemblfungi:YBL093C	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med19_yeast(display_long)|uniprotkb:NUT3(gene name synonym)|uniprotkb:ROX3(gene name)|psi-mi:ROX3(display_short)|uniprotkb:YBL093C(locus name)|uniprotkb:YBL0837(orf name)|uniprotkb:MED19(gene name synonym)|uniprotkb:SSN7(gene name synonym)|uniprotkb:Mediator complex subunit 19(gene name synonym)|uniprotkb:Hypoxic gene repressor protein 3(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 3(gene name synonym)|uniprotkb:SNF1 suppressor protein 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	refseq:NP_009459.1|sgd:S000000189|ensemblfungi:YBL093C(gene)|ensemblfungi:YBL093C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR013942(Mediator complex, subunit MED19)|rcsb pdb:5OQM|dip:DIP-2336N|mint:P25046	-	crc64:7703E4FAE101A31F	-	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:kxFkbBROQD1kjcYzVZYX+bcvPOo559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:P34162	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-18018|uniprotkb:D3DKY9|ensemblfungi:YHR041C	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med20_yeast(display_long)|uniprotkb:YHR041C(locus name)|uniprotkb:SRB2(gene name)|psi-mi:SRB2(display_short)|uniprotkb:HRS2(gene name synonym)|uniprotkb:MED20(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 2(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	refseq:NP_011907.1|sgd:S000001083|ensemblfungi:YHR041C(gene)|ensemblfungi:YHR041C_mRNA(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010689"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0016592"(mediator complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR013921(TATA-binding related factor)|interpro:IPR016532(Mediator complex, subunit 20)|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|dip:DIP-107N|mint:P34162	-	crc64:7703E4FAE101A31F	crc64:C30BF309D43AFB2A	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:D2Zs1KYyPj3RbDQC4fz/XtWL+s0559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:P38304	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N	-	crc64:7703E4FAE101A31F	crc64:86B2A064293C6B61	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:UdED273ourIyAm1t31wIqC/kKX8559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:P32569	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569	-	crc64:7703E4FAE101A31F	crc64:D25B2993A1BADFD6	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:P33308	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-5174|uniprotkb:D6W1I5|ensemblfungi:YNR010W	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med9_yeast(display_long)|uniprotkb:CSE2(gene name)|psi-mi:CSE2(display_short)|uniprotkb:YNR010W(locus name)|uniprotkb:N2046(orf name)|uniprotkb:MED9(gene name synonym)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:Chromosome segregation protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	sgd:S000005293|refseq:NP_014407.3|dip:DIP-1276N|mint:P33308|ensemblfungi:YNR010W(gene)|ensemblfungi:YNR010W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|rcsb pdb:5OQM|rcsb pdb:5SVA	-	crc64:7703E4FAE101A31F	crc64:99D2347F5287AA3C	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:EHc+XpAIJ3NEiV9uMRTYHy437+U559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:P40356	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-13268|uniprotkb:Q6B1W3|uniprotkb:D6VUB3|ensemblfungi:YGL025C	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med3_yeast(display_long)|uniprotkb:PGD1(gene name)|psi-mi:PGD1(display_short)|uniprotkb:YGL025C(locus name)|uniprotkb:HRS1(gene name synonym)|uniprotkb:MED3(gene name synonym)|uniprotkb:Mediator complex subunit 3(gene name synonym)|uniprotkb:Poly-glutamine domain protein 1(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	refseq:NP_011490.2|sgd:S000002993|mint:P40356|dip:DIP-1186N|ensemblfungi:YGL025C(gene)|ensemblfungi:YGL025C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR020998	-	crc64:7703E4FAE101A31F	-	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:oymzNX+JOJG3JMQDdW+3UHzvGzo559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:Q06213	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	-	crc64:7703E4FAE101A31F	crc64:0E77A43A5222E862	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:Q08278	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-10674|ensemblfungi:YOL135C|uniprotkb:D6W1T4	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med7_yeast(display_long)|uniprotkb:YOL135C(locus name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	refseq:NP_014506.1|sgd:S000005495|ensemblfungi:YOL135C(gene)|ensemblfungi:YOL135C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|mint:Q08278|dip:DIP-1435N	-	crc64:7703E4FAE101A31F	-	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:26cG32mQDDL8kzdV8k11wI3Yc8w559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:Q12124	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-37542|uniprotkb:D6VRY3|ensemblfungi:YDL005C	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med2_yeast(display_long)|uniprotkb:MED2(gene name)|psi-mi:MED2(display_short)|uniprotkb:D2930(orf name)|uniprotkb:Mediator complex subunit 2(gene name synonym)|uniprotkb:YDL005C(locus name)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	sgd:S000002163|refseq:NP_010279.3|dip:DIP-2335N|mint:Q12124|ensemblfungi:YDL005C(gene)|ensemblfungi:YDL005C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021017	-	crc64:7703E4FAE101A31F	crc64:D3B0992B1F1A4892	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:pg7IrzDZIzNxuyB+GlZsguqLJEI559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:Q12321	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-32854|uniprotkb:D6W474|ensemblfungi:YPR070W	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med1_yeast(display_long)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:YPR063W(orf name)|uniprotkb:YPR070W(locus name)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:YP9499.25(orf name)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	refseq:NP_015395.1|sgd:S000006274|mint:Q12321|dip:DIP-1690N|ensemblfungi:YPR070W(gene)|ensemblfungi:YPR070W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019680	-	crc64:7703E4FAE101A31F	-	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:vi5smmBUyBLAQ8WbXtFeiAYiA/8559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32570	uniprotkb:P47822	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	intact:EBI-18046|uniprotkb:D6VST7|ensemblfungi:YDR308C	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:med21_yeast(display_long)|uniprotkb:SRB7(gene name)|psi-mi:SRB7(display_short)|uniprotkb:YDR308C(locus name)|uniprotkb:D9740.17(orf name)|uniprotkb:MED21(gene name synonym)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNAPII complex component SRB7(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694385|imex:IM-23033-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	sgd:S000002716|ensemblfungi:YDR308C(gene)|ensemblfungi:YDR308C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_010594.3|dip:DIP-290N|mint:P47822	-	crc64:7703E4FAE101A31F	crc64:C5B3474AF8DD662A	figure legend:Supp. Fig. 2A, 2B|comment:A ranges of different MBP-tagged proteins was made, and the mediator complex containing each purified, to enable mapping of the proteins within the mediator complex. Pulldowns were also performed in strains deleted of a specific protein, however the effects on pulldown of the complexes could not be clearly viewed,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	rogid:jlA37XsCdchAsMRiyYLvj20MkiY559292	intact-crc:D4110B5660E856F7|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P32259	uniprotkb:P53114	intact:EBI-17172|ensemblfungi:YNL236W|uniprotkb:D6W0V7	intact:EBI-12407|ensemblfungi:YGL151W|uniprotkb:D6VTZ9	psi-mi:med16_yeast(display_long)|uniprotkb:SIN4(gene name)|psi-mi:SIN4(display_short)|uniprotkb:BEL2(gene name synonym)|uniprotkb:GAL22(gene name synonym)|uniprotkb:SSF5(gene name synonym)|uniprotkb:YNL236W(locus name)|uniprotkb:N1135(orf name)|uniprotkb:TSF3(gene name synonym)|uniprotkb:MED16(gene name synonym)|uniprotkb:RYE1(gene name synonym)|uniprotkb:SDI3(gene name synonym)|uniprotkb:SSN4(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Global transcriptional regulator SIN4(gene name synonym)|uniprotkb:YGP1 expression regulatory protein 1(gene name synonym)|uniprotkb:Transcriptional silencing factor 3(gene name synonym)|uniprotkb:SWI4 suppressor protein 5(gene name synonym)|uniprotkb:SNF1 suppressor protein 4(gene name synonym)	psi-mi:med5_yeast(display_long)|uniprotkb:NUT1(gene name)|psi-mi:NUT1(display_short)|uniprotkb:YGL151W(locus name)|uniprotkb:G1876(orf name)|uniprotkb:MED5(gene name synonym)|uniprotkb:Mediator complex subunit 5(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694502|imex:IM-23033-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014163.1|sgd:S000005180|ensemblfungi:YNL236W(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070202"(regulation of establishment of protein localization to chromosome)|go:"GO:0070847"(core mediator complex)|interpro:IPR021665|ensemblfungi:YNL236W_mRNA(transcript)|dip:DIP-1617N|mint:P32259	ensemblfungi:YGL151W(gene)|ensemblfungi:YGL151W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR014801(Mediator complex, subunit Med5)|refseq:NP_011364.1|sgd:S000003119|mint:P53114|dip:DIP-6632N	-	crc64:12ECF5E4CDC05A8E	crc64:BBD54661A4DB5F09	figure legend:Supp. Fig. 3E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:krTYeU9eXPNnPWcoz+idZe7fRIE559292	rogid:PZX5GBu0/S00vR1eP3R7UYjX6Sk559292	intact-crc:3A53992E3FE189E2|rigid:fabAAbcjXBb53GoqxE9l5q5qPCY	false	calmodulin binding peptide plus protein a tag:c-c|sufficient binding region:1-866	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:Q12124	uniprotkb:P19659	intact:EBI-37542|uniprotkb:D6VRY3|ensemblfungi:YDL005C	intact:EBI-7305|uniprotkb:Q08221|uniprotkb:D6W217|ensemblfungi:YOL051W	psi-mi:med2_yeast(display_long)|uniprotkb:MED2(gene name)|psi-mi:MED2(display_short)|uniprotkb:D2930(orf name)|uniprotkb:Mediator complex subunit 2(gene name synonym)|uniprotkb:YDL005C(locus name)	psi-mi:med15_yeast(display_long)|uniprotkb:YOL051W(locus name)|uniprotkb:GAL11(gene name)|psi-mi:GAL11(display_short)|uniprotkb:RAR3(gene name synonym)|uniprotkb:SPT13(gene name synonym)|uniprotkb:ABE1(gene name synonym)|uniprotkb:MED15(gene name synonym)|uniprotkb:SDS4(gene name synonym)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Transcription regulatory protein GAL11(gene name synonym)|uniprotkb:Basal expression activator protein 1(gene name synonym)|uniprotkb:Autonomous replication regulatory protein 3(gene name synonym)|uniprotkb:Defective silencing suppressor protein 4(gene name synonym)|uniprotkb:Ty insertion suppressor protein 13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694510|imex:IM-23033-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002163|refseq:NP_010279.3|dip:DIP-2335N|mint:Q12124|ensemblfungi:YDL005C(gene)|ensemblfungi:YDL005C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021017	refseq:NP_014591.1|sgd:S000005411|mint:P19659|dip:DIP-2334N|ensemblfungi:YOL051W(gene)|ensemblfungi:YOL051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001095"(TFIIE-class transcription factor complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070202"(regulation of establishment of protein localization to chromosome)|go:"GO:0070847"(core mediator complex)|go:"GO:2000219"(positive regulation of invasive growth in response to glucose limitation)|interpro:IPR008626(GAL11 transcriptional regulator)|interpro:IPR033789|interpro:IPR036529|interpro:IPR036546|rcsb pdb:2K0N|rcsb pdb:2LPB|rcsb pdb:6ALY	-	crc64:D3B0992B1F1A4892	crc64:275C78721B5415C7	figure legend:Supp. Fig. 3F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:pg7IrzDZIzNxuyB+GlZsguqLJEI559292	rogid:wkvx9dInmIwvGKlHPvoOtY9QmAY559292	intact-crc:DB9A1EF86FEBFA26|rigid:cp0p/9S6U1DvyV8Np2hOxqPTGmc	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:Q12124	uniprotkb:P40356	intact:EBI-37542|uniprotkb:D6VRY3|ensemblfungi:YDL005C	intact:EBI-13268|uniprotkb:Q6B1W3|uniprotkb:D6VUB3|ensemblfungi:YGL025C	psi-mi:med2_yeast(display_long)|uniprotkb:MED2(gene name)|psi-mi:MED2(display_short)|uniprotkb:D2930(orf name)|uniprotkb:Mediator complex subunit 2(gene name synonym)|uniprotkb:YDL005C(locus name)	psi-mi:med3_yeast(display_long)|uniprotkb:PGD1(gene name)|psi-mi:PGD1(display_short)|uniprotkb:YGL025C(locus name)|uniprotkb:HRS1(gene name synonym)|uniprotkb:MED3(gene name synonym)|uniprotkb:Mediator complex subunit 3(gene name synonym)|uniprotkb:Poly-glutamine domain protein 1(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694510|imex:IM-23033-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002163|refseq:NP_010279.3|dip:DIP-2335N|mint:Q12124|ensemblfungi:YDL005C(gene)|ensemblfungi:YDL005C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021017	refseq:NP_011490.2|sgd:S000002993|mint:P40356|dip:DIP-1186N|ensemblfungi:YGL025C(gene)|ensemblfungi:YGL025C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR020998	-	crc64:D3B0992B1F1A4892	-	figure legend:Supp. Fig. 3F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:pg7IrzDZIzNxuyB+GlZsguqLJEI559292	rogid:oymzNX+JOJG3JMQDdW+3UHzvGzo559292	intact-crc:DB9A1EF86FEBFA26|rigid:cp0p/9S6U1DvyV8Np2hOxqPTGmc	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:Q06213	uniprotkb:Q99278	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-27213|uniprotkb:D6VZT5	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA	-	crc64:0E77A43A5222E862	crc64:457D13C6030F33CC	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P19263	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-15087|uniprotkb:Q07999|uniprotkb:D6VY72|ensemblfungi:YLR071C	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med14_yeast(display_long)|uniprotkb:RGR1(gene name)|psi-mi:RGR1(display_short)|uniprotkb:MED14(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Glucose repression regulatory protein 1(gene name synonym)|uniprotkb:YLR071C(locus name)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	refseq:NP_013172.1|sgd:S000004061|ensemblfungi:YLR071C(gene)|ensemblfungi:YLR071C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|rcsb pdb:5OQM|dip:DIP-1562N|mint:P19263	-	crc64:0E77A43A5222E862	crc64:96277001829DB539	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:WbZxedNQBe+lFVW5hCxmuyAc4r8559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P19659	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-7305|uniprotkb:Q08221|uniprotkb:D6W217|ensemblfungi:YOL051W	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med15_yeast(display_long)|uniprotkb:YOL051W(locus name)|uniprotkb:GAL11(gene name)|psi-mi:GAL11(display_short)|uniprotkb:RAR3(gene name synonym)|uniprotkb:SPT13(gene name synonym)|uniprotkb:ABE1(gene name synonym)|uniprotkb:MED15(gene name synonym)|uniprotkb:SDS4(gene name synonym)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Transcription regulatory protein GAL11(gene name synonym)|uniprotkb:Basal expression activator protein 1(gene name synonym)|uniprotkb:Autonomous replication regulatory protein 3(gene name synonym)|uniprotkb:Defective silencing suppressor protein 4(gene name synonym)|uniprotkb:Ty insertion suppressor protein 13(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	refseq:NP_014591.1|sgd:S000005411|mint:P19659|dip:DIP-2334N|ensemblfungi:YOL051W(gene)|ensemblfungi:YOL051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001095"(TFIIE-class transcription factor complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070202"(regulation of establishment of protein localization to chromosome)|go:"GO:0070847"(core mediator complex)|go:"GO:2000219"(positive regulation of invasive growth in response to glucose limitation)|interpro:IPR008626(GAL11 transcriptional regulator)|interpro:IPR033789|interpro:IPR036529|interpro:IPR036546|rcsb pdb:2K0N|rcsb pdb:2LPB|rcsb pdb:6ALY	-	crc64:0E77A43A5222E862	crc64:275C78721B5415C7	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:wkvx9dInmIwvGKlHPvoOtY9QmAY559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P32259	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-17172|ensemblfungi:YNL236W|uniprotkb:D6W0V7	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med16_yeast(display_long)|uniprotkb:SIN4(gene name)|psi-mi:SIN4(display_short)|uniprotkb:BEL2(gene name synonym)|uniprotkb:GAL22(gene name synonym)|uniprotkb:SSF5(gene name synonym)|uniprotkb:YNL236W(locus name)|uniprotkb:N1135(orf name)|uniprotkb:TSF3(gene name synonym)|uniprotkb:MED16(gene name synonym)|uniprotkb:RYE1(gene name synonym)|uniprotkb:SDI3(gene name synonym)|uniprotkb:SSN4(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Global transcriptional regulator SIN4(gene name synonym)|uniprotkb:YGP1 expression regulatory protein 1(gene name synonym)|uniprotkb:Transcriptional silencing factor 3(gene name synonym)|uniprotkb:SWI4 suppressor protein 5(gene name synonym)|uniprotkb:SNF1 suppressor protein 4(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	refseq:NP_014163.1|sgd:S000005180|ensemblfungi:YNL236W(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070202"(regulation of establishment of protein localization to chromosome)|go:"GO:0070847"(core mediator complex)|interpro:IPR021665|ensemblfungi:YNL236W_mRNA(transcript)|dip:DIP-1617N|mint:P32259	-	crc64:0E77A43A5222E862	crc64:12ECF5E4CDC05A8E	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:krTYeU9eXPNnPWcoz+idZe7fRIE559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P32569	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569	-	crc64:0E77A43A5222E862	crc64:D25B2993A1BADFD6	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P32585	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585	-	crc64:0E77A43A5222E862	crc64:B1148FC187C2802A	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:+/qC0affGDlvusbTV43B3aCgZBU559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P25046	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-15722|uniprotkb:D6VPR0|ensemblfungi:YBL093C	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med19_yeast(display_long)|uniprotkb:NUT3(gene name synonym)|uniprotkb:ROX3(gene name)|psi-mi:ROX3(display_short)|uniprotkb:YBL093C(locus name)|uniprotkb:YBL0837(orf name)|uniprotkb:MED19(gene name synonym)|uniprotkb:SSN7(gene name synonym)|uniprotkb:Mediator complex subunit 19(gene name synonym)|uniprotkb:Hypoxic gene repressor protein 3(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 3(gene name synonym)|uniprotkb:SNF1 suppressor protein 7(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	refseq:NP_009459.1|sgd:S000000189|ensemblfungi:YBL093C(gene)|ensemblfungi:YBL093C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR013942(Mediator complex, subunit MED19)|rcsb pdb:5OQM|dip:DIP-2336N|mint:P25046	-	crc64:0E77A43A5222E862	-	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:kxFkbBROQD1kjcYzVZYX+bcvPOo559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:Q12321	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-32854|uniprotkb:D6W474|ensemblfungi:YPR070W	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med1_yeast(display_long)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:YPR063W(orf name)|uniprotkb:YPR070W(locus name)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:YP9499.25(orf name)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	refseq:NP_015395.1|sgd:S000006274|mint:Q12321|dip:DIP-1690N|ensemblfungi:YPR070W(gene)|ensemblfungi:YPR070W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019680	-	crc64:0E77A43A5222E862	-	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:vi5smmBUyBLAQ8WbXtFeiAYiA/8559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P34162	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-18018|uniprotkb:D3DKY9|ensemblfungi:YHR041C	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med20_yeast(display_long)|uniprotkb:YHR041C(locus name)|uniprotkb:SRB2(gene name)|psi-mi:SRB2(display_short)|uniprotkb:HRS2(gene name synonym)|uniprotkb:MED20(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 2(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 2(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	refseq:NP_011907.1|sgd:S000001083|ensemblfungi:YHR041C(gene)|ensemblfungi:YHR041C_mRNA(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010689"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0016592"(mediator complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR013921(TATA-binding related factor)|interpro:IPR016532(Mediator complex, subunit 20)|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|dip:DIP-107N|mint:P34162	-	crc64:0E77A43A5222E862	crc64:C30BF309D43AFB2A	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:D2Zs1KYyPj3RbDQC4fz/XtWL+s0559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P47822	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-18046|uniprotkb:D6VST7|ensemblfungi:YDR308C	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med21_yeast(display_long)|uniprotkb:SRB7(gene name)|psi-mi:SRB7(display_short)|uniprotkb:YDR308C(locus name)|uniprotkb:D9740.17(orf name)|uniprotkb:MED21(gene name synonym)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNAPII complex component SRB7(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 7(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	sgd:S000002716|ensemblfungi:YDR308C(gene)|ensemblfungi:YDR308C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_010594.3|dip:DIP-290N|mint:P47822	-	crc64:0E77A43A5222E862	crc64:C5B3474AF8DD662A	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:jlA37XsCdchAsMRiyYLvj20MkiY559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P32570	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570	-	crc64:0E77A43A5222E862	crc64:7703E4FAE101A31F	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:Q12124	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-37542|uniprotkb:D6VRY3|ensemblfungi:YDL005C	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med2_yeast(display_long)|uniprotkb:MED2(gene name)|psi-mi:MED2(display_short)|uniprotkb:D2930(orf name)|uniprotkb:Mediator complex subunit 2(gene name synonym)|uniprotkb:YDL005C(locus name)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	sgd:S000002163|refseq:NP_010279.3|dip:DIP-2335N|mint:Q12124|ensemblfungi:YDL005C(gene)|ensemblfungi:YDL005C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021017	-	crc64:0E77A43A5222E862	crc64:D3B0992B1F1A4892	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:pg7IrzDZIzNxuyB+GlZsguqLJEI559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P38633	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-17658|uniprotkb:D6VU21|ensemblfungi:YGL127C	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med31_yeast(display_long)|uniprotkb:SOH1(gene name)|psi-mi:SOH1(display_short)|uniprotkb:YGL127C(locus name)|uniprotkb:G2864(orf name)|uniprotkb:MED31(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Hpr1 suppressor protein 1(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	ensemblfungi:YGL127C(gene)|ensemblfungi:YGL127C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_011388.1|sgd:S000003095|dip:DIP-1179N|mint:P38633	-	crc64:0E77A43A5222E862	-	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:7jJUtvDYjsYKT1AcECsAgyDmlPw559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P40356	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-13268|uniprotkb:Q6B1W3|uniprotkb:D6VUB3|ensemblfungi:YGL025C	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med3_yeast(display_long)|uniprotkb:PGD1(gene name)|psi-mi:PGD1(display_short)|uniprotkb:YGL025C(locus name)|uniprotkb:HRS1(gene name synonym)|uniprotkb:MED3(gene name synonym)|uniprotkb:Mediator complex subunit 3(gene name synonym)|uniprotkb:Poly-glutamine domain protein 1(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 1(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	refseq:NP_011490.2|sgd:S000002993|mint:P40356|dip:DIP-1186N|ensemblfungi:YGL025C(gene)|ensemblfungi:YGL025C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR020998	-	crc64:0E77A43A5222E862	-	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:oymzNX+JOJG3JMQDdW+3UHzvGzo559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:Q12343	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-31503|uniprotkb:D6W2N0|ensemblfungi:YOR174W	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med4_yeast(display_long)|uniprotkb:O3630(orf name)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:YOR174W(locus name)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	sgd:S000005700|refseq:NP_014817.3|dip:DIP-1178N|mint:Q12343|ensemblfungi:YOR174W(gene)|ensemblfungi:YOR174W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|rcsb pdb:5OQM|rcsb pdb:5SVA	-	crc64:0E77A43A5222E862	crc64:D42A3C62D465DDAD	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:R+wCh3eGS74E+DEQm21XHMd59y0559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P53114	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-12407|ensemblfungi:YGL151W|uniprotkb:D6VTZ9	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med5_yeast(display_long)|uniprotkb:NUT1(gene name)|psi-mi:NUT1(display_short)|uniprotkb:YGL151W(locus name)|uniprotkb:G1876(orf name)|uniprotkb:MED5(gene name synonym)|uniprotkb:Mediator complex subunit 5(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 1(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	ensemblfungi:YGL151W(gene)|ensemblfungi:YGL151W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR014801(Mediator complex, subunit Med5)|refseq:NP_011364.1|sgd:S000003119|mint:P53114|dip:DIP-6632N	-	crc64:0E77A43A5222E862	crc64:BBD54661A4DB5F09	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:PZX5GBu0/S00vR1eP3R7UYjX6Sk559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P38782	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-10667|ensemblfungi:YHR058C|uniprotkb:D3DL07	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med6_yeast(display_long)|uniprotkb:MTR32(gene name synonym)|uniprotkb:YHR058C(locus name)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	refseq:NP_011925.1|sgd:S000001100|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016612(Mediator complex, subunit 6, fungi)|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YHR058C(gene)|ensemblfungi:YHR058C_mRNA(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|mint:P38782|dip:DIP-2093N	-	crc64:0E77A43A5222E862	crc64:B84E87DCC2737849	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:XcKvvx/GJGRLZpv1MPzpPtVd2RI559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:Q08278	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-10674|ensemblfungi:YOL135C|uniprotkb:D6W1T4	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med7_yeast(display_long)|uniprotkb:YOL135C(locus name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	refseq:NP_014506.1|sgd:S000005495|ensemblfungi:YOL135C(gene)|ensemblfungi:YOL135C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|mint:Q08278|dip:DIP-1435N	-	crc64:0E77A43A5222E862	-	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:26cG32mQDDL8kzdV8k11wI3Yc8w559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P38304	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N	-	crc64:0E77A43A5222E862	crc64:86B2A064293C6B61	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:UdED273ourIyAm1t31wIqC/kKX8559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06213	uniprotkb:P33308	intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9	intact:EBI-5174|uniprotkb:D6W1I5|ensemblfungi:YNR010W	psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym)	psi-mi:med9_yeast(display_long)|uniprotkb:CSE2(gene name)|psi-mi:CSE2(display_short)|uniprotkb:YNR010W(locus name)|uniprotkb:N2046(orf name)|uniprotkb:MED9(gene name synonym)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:Chromosome segregation protein 2(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Tsai et al. (2014)	pubmed:24882805|imex:IM-23033	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9694458|imex:IM-23033-2|emdb:EMD-2634	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N	sgd:S000005293|refseq:NP_014407.3|dip:DIP-1276N|mint:P33308|ensemblfungi:YNR010W(gene)|ensemblfungi:YNR010W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|rcsb pdb:5OQM|rcsb pdb:5SVA	-	crc64:0E77A43A5222E862	crc64:99D2347F5287AA3C	figure legend:Figs. 1, 2, 3 Supp. Figs. 1, 3A-D,|comment:MBP fusion proteins were used to assign proteins to the head, middle and tail sub-modules.   Head - Med6, Med8, Med11, Med17, Med18, Med20, Med22  Middle - Med1, Med4, Med7, Med9, Med10, Med19, Med21, Med31  Tail - Med2, Med3, Med5, Med14, Med15, Med16|3d-resolution:1.8nm|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/08/27	2014/10/16	rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292	rogid:EHc+XpAIJ3NEiV9uMRTYHy437+U559292	intact-crc:23FC6B026BD47E96|rigid:LjoO6Q5LG4vZUGyA0gtJkeDINyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)