#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P84889 uniprotkb:D4A3W8 intact:EBI-8512324|intact:MINT-8416720|ensembl:ENSRNOP00000006849|ensembl:ENSRNOP00000072619 intact:EBI-9538675|ensembl:ENSRNOP00000011466 psi-mi:vang2_rat(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Van Gogh-like protein 2(gene name synonym) psi-mi:d4a3w8_rat(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Hagenmueller et al. (2014) pubmed:24879894|imex:IM-22629 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9538672|imex:IM-22629-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1309442|refseq:NP_001099439.1|refseq:XP_006250338.1|refseq:XP_006250339.1|refseq:XP_017454201.1|refseq:XP_017454202.1|ensembl:ENSRNOG00000004889(gene)|ensembl:ENSRNOT00000006849(transcript)|ensembl:ENSRNOT00000091710(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:P84889|reactome:R-RNO-9696264|reactome:R-RNO-9696270|reactome:R-RNO-9696273|go:"GO:0016323"(basolateral plasma membrane) rgd:1564008|refseq:XP_001077448.1|refseq:XP_576044.1|ensembl:ENSRNOG00000008445(gene)|ensembl:ENSRNOT00000011466(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-RNO-4641258 go:"GO:0048471"(perinuclear region of cytoplasm) comment:mint|comment:homomint - figure legend:f4g|comment:"Moreover, co-immunostaining of Dpr1 and Vangl2 in untreated, isolated cardiomyocytes revealed a co-localization in perinuclear areas but not in the cytoplasm and in regions of the cell membrane (Fig. 4G)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-cardiac_myocytes_neo)|taxid:10116(rat cardiac myocytes neo) - 2014/05/21 2014/10/16 rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10116 rogid:JHsVzLMVh5gmFN8csrFZJCZ8nRU10116 intact-crc:DFBA86D1F0EE10C6|rigid:+VI3TXeaKw2LG3//oJfuNxz7by4 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)