#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:A6Q0K5	uniprotkb:P50362	intact:EBI-9538486|uniprotkb:A8IZ71|ensemblplants:PNW80155	intact:EBI-9538536|ensemblplants:PNW88018	psi-mi:cp12_chlre(display_long)|uniprotkb:CP12(gene name)|psi-mi:CP12(display_short)|uniprotkb:CP12 domain-containing protein(gene name synonym)|uniprotkb:Chloroplast protein 12(gene name synonym)|uniprotkb:CHLREDRAFT_148487(orf name)	psi-mi:g3pa_chlre(display_long)|uniprotkb:GAPA(gene name)|psi-mi:GAPA(display_short)|uniprotkb:NADP-dependent glyceraldehydephosphate dehydrogenase subunit A(gene name synonym)	psi-mi:"MI:0052"(fluorescence correlation spectroscopy)	Moparthi et al. (2014)	pubmed:24863370|imex:IM-22628	taxid:3055(chlre)|taxid:3055(Chlamydomonas reinhardtii)	taxid:3055(chlre)|taxid:3055(Chlamydomonas reinhardtii)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9538525|imex:IM-22628-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003823(Protein of unknown function CP12)|rcsb pdb:2DDN|refseq:XP_001694345.1|interpro:IPR039314|ensemblplants:CHLRE_08g380250v5(gene)|ensemblplants:PNW80155(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0009507"(chloroplast)|go:"GO:0016151"(nickel cation binding)|go:"GO:0019253"(reductive pentose-phosphate cycle)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080153"(negative regulation of reductive pentose-phosphate cycle)|go:"GO:0099080"(supramolecular complex)	interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|rcsb pdb:1NLG|rcsb pdb:1NLH|refseq:XP_001689871.1|interpro:IPR036291|ensemblplants:CHLRE_01g010900v5(gene)|ensemblplants:PNW88018(transcript)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0009507"(chloroplast)|go:"GO:0019253"(reductive pentose-phosphate cycle)|go:"GO:0019900"(kinase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0047100"("glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity")|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|go:"GO:0099080"(supramolecular complex)	-	-	-	figure legend:T1 T2 F2 F3 F4|comment:Our results showed that the disruption of the N-terminal disulfide bridge on CP12 affects   the formation of the CP12C31S-PRK complex, while it has no effect on the CP12C31S-GAPDH   complex. On the other hand, we observed the opposite effect with the mutant CP12C75S   affected at the C-terminal disulfide bridge that forms a complex with PRK but not with GAPDH.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/05/21	2014/10/16	rogid:H0azjhpY8+CThINeZhUWkWLQVKA3055	rogid:PvLvp8EdDm2crPPFYigjsm4xaHI3055	intact-crc:CBFDD9375EF945D2|rigid:dc7u9sLQ+cnSJpPWqV/8Q374S/w	false	mutation decreasing interaction:75-75|fluorophore:?-?	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A6Q0K5	uniprotkb:P50362	intact:EBI-9538486|uniprotkb:A8IZ71|ensemblplants:PNW80155	intact:EBI-9538536|ensemblplants:PNW88018	psi-mi:cp12_chlre(display_long)|uniprotkb:CP12(gene name)|psi-mi:CP12(display_short)|uniprotkb:CP12 domain-containing protein(gene name synonym)|uniprotkb:Chloroplast protein 12(gene name synonym)|uniprotkb:CHLREDRAFT_148487(orf name)	psi-mi:g3pa_chlre(display_long)|uniprotkb:GAPA(gene name)|psi-mi:GAPA(display_short)|uniprotkb:NADP-dependent glyceraldehydephosphate dehydrogenase subunit A(gene name synonym)	psi-mi:"MI:0052"(fluorescence correlation spectroscopy)	Moparthi et al. (2014)	pubmed:24863370|imex:IM-22628	taxid:3055(chlre)|taxid:3055(Chlamydomonas reinhardtii)	taxid:3055(chlre)|taxid:3055(Chlamydomonas reinhardtii)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9538539|imex:IM-22628-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003823(Protein of unknown function CP12)|rcsb pdb:2DDN|refseq:XP_001694345.1|interpro:IPR039314|ensemblplants:CHLRE_08g380250v5(gene)|ensemblplants:PNW80155(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0009507"(chloroplast)|go:"GO:0016151"(nickel cation binding)|go:"GO:0019253"(reductive pentose-phosphate cycle)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080153"(negative regulation of reductive pentose-phosphate cycle)|go:"GO:0099080"(supramolecular complex)	interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|rcsb pdb:1NLG|rcsb pdb:1NLH|refseq:XP_001689871.1|interpro:IPR036291|ensemblplants:CHLRE_01g010900v5(gene)|ensemblplants:PNW88018(transcript)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0009507"(chloroplast)|go:"GO:0019253"(reductive pentose-phosphate cycle)|go:"GO:0019900"(kinase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0047100"("glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity")|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|go:"GO:0099080"(supramolecular complex)	-	-	-	figure legend:T1 T2 F2 F3 F4|comment:Our results showed that the disruption of the N-terminal disulfide bridge on CP12 affects   the formation of the CP12C31S-PRK complex, while it has no effect on the CP12C31S-GAPDH   complex. On the other hand, we observed the opposite effect with the mutant CP12C75S   affected at the C-terminal disulfide bridge that forms a complex with PRK but not with GAPDH.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/05/21	2014/10/16	rogid:H0azjhpY8+CThINeZhUWkWLQVKA3055	rogid:PvLvp8EdDm2crPPFYigjsm4xaHI3055	intact-crc:17EA902887563DD8|rigid:le3HzcTZAijEqb3TGtEBhs3X86M	false	fluorophore:?-?|mutation decreasing interaction:75-75	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A6Q0K5	uniprotkb:P19824	intact:EBI-9538486|uniprotkb:A8IZ71|ensemblplants:PNW80155	intact:EBI-9538490|ensemblplants:PNW75922	psi-mi:cp12_chlre(display_long)|uniprotkb:CP12(gene name)|psi-mi:CP12(display_short)|uniprotkb:CP12 domain-containing protein(gene name synonym)|uniprotkb:Chloroplast protein 12(gene name synonym)|uniprotkb:CHLREDRAFT_148487(orf name)	psi-mi:kppr_chlre(display_long)|uniprotkb:PRKA(gene name)|psi-mi:PRKA(display_short)|uniprotkb:Phosphopentokinase(gene name synonym)	psi-mi:"MI:0052"(fluorescence correlation spectroscopy)	Moparthi et al. (2014)	pubmed:24863370|imex:IM-22628	taxid:3055(chlre)|taxid:3055(Chlamydomonas reinhardtii)	taxid:3055(chlre)|taxid:3055(Chlamydomonas reinhardtii)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9538539|imex:IM-22628-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003823(Protein of unknown function CP12)|rcsb pdb:2DDN|refseq:XP_001694345.1|interpro:IPR039314|ensemblplants:CHLRE_08g380250v5(gene)|ensemblplants:PNW80155(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0009507"(chloroplast)|go:"GO:0016151"(nickel cation binding)|go:"GO:0019253"(reductive pentose-phosphate cycle)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080153"(negative regulation of reductive pentose-phosphate cycle)|go:"GO:0099080"(supramolecular complex)	interpro:IPR006082(Phosphoribulokinase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417|refseq:XP_001694038.1|rcsb pdb:6H7G|ensemblplants:CHLRE_12g554800v5(gene)|ensemblplants:PNW75922(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0008974"(phosphoribulokinase activity)|go:"GO:0009409"(response to cold)|go:"GO:0009507"(chloroplast)|go:"GO:0009535"(chloroplast thylakoid membrane)|go:"GO:0009570"(chloroplast stroma)|go:"GO:0009941"(chloroplast envelope)|go:"GO:0010319"(stromule)|go:"GO:0019253"(reductive pentose-phosphate cycle)|go:"GO:0019899"(enzyme binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048046"(apoplast)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099080"(supramolecular complex)	-	-	-	figure legend:T1 T2 F2 F3 F4|comment:Our results showed that the disruption of the N-terminal disulfide bridge on CP12 affects   the formation of the CP12C31S-PRK complex, while it has no effect on the CP12C31S-GAPDH   complex. On the other hand, we observed the opposite effect with the mutant CP12C75S   affected at the C-terminal disulfide bridge that forms a complex with PRK but not with GAPDH.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/05/21	2014/10/16	rogid:H0azjhpY8+CThINeZhUWkWLQVKA3055	rogid:wnhYAbgg8JbodBfAWxu/r5qsW/M3055	intact-crc:17EA902887563DD8|rigid:le3HzcTZAijEqb3TGtEBhs3X86M	false	fluorophore:?-?|mutation decreasing interaction:75-75	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P19824	uniprotkb:A6Q0K5	intact:EBI-9538490|ensemblplants:PNW75922	intact:EBI-9538486|uniprotkb:A8IZ71|ensemblplants:PNW80155	psi-mi:kppr_chlre(display_long)|uniprotkb:PRKA(gene name)|psi-mi:PRKA(display_short)|uniprotkb:Phosphopentokinase(gene name synonym)	psi-mi:cp12_chlre(display_long)|uniprotkb:CP12(gene name)|psi-mi:CP12(display_short)|uniprotkb:CP12 domain-containing protein(gene name synonym)|uniprotkb:Chloroplast protein 12(gene name synonym)|uniprotkb:CHLREDRAFT_148487(orf name)	psi-mi:"MI:0052"(fluorescence correlation spectroscopy)	Moparthi et al. (2014)	pubmed:24863370|imex:IM-22628	taxid:3055(chlre)|taxid:3055(Chlamydomonas reinhardtii)	taxid:3055(chlre)|taxid:3055(Chlamydomonas reinhardtii)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9538484|imex:IM-22628-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006082(Phosphoribulokinase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417|refseq:XP_001694038.1|rcsb pdb:6H7G|ensemblplants:CHLRE_12g554800v5(gene)|ensemblplants:PNW75922(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0008974"(phosphoribulokinase activity)|go:"GO:0009409"(response to cold)|go:"GO:0009507"(chloroplast)|go:"GO:0009535"(chloroplast thylakoid membrane)|go:"GO:0009570"(chloroplast stroma)|go:"GO:0009941"(chloroplast envelope)|go:"GO:0010319"(stromule)|go:"GO:0019253"(reductive pentose-phosphate cycle)|go:"GO:0019899"(enzyme binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048046"(apoplast)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099080"(supramolecular complex)	interpro:IPR003823(Protein of unknown function CP12)|rcsb pdb:2DDN|refseq:XP_001694345.1|interpro:IPR039314|ensemblplants:CHLRE_08g380250v5(gene)|ensemblplants:PNW80155(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0009507"(chloroplast)|go:"GO:0016151"(nickel cation binding)|go:"GO:0019253"(reductive pentose-phosphate cycle)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080153"(negative regulation of reductive pentose-phosphate cycle)|go:"GO:0099080"(supramolecular complex)	-	-	-	figure legend:T1 T2 F2 F3 F4|comment:Our results showed that the disruption of the N-terminal disulfide bridge on CP12 affects   the formation of the CP12C31S-PRK complex, while it has no effect on the CP12C31S-GAPDH   complex. On the other hand, we observed the opposite effect with the mutant CP12C75S   affected at the C-terminal disulfide bridge that forms a complex with PRK but not with GAPDH.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/05/21	2014/10/16	rogid:wnhYAbgg8JbodBfAWxu/r5qsW/M3055	rogid:H0azjhpY8+CThINeZhUWkWLQVKA3055	intact-crc:DA820114612428CC|rigid:7x5MH4KP3etnnoecbDko2rW5njw	false	-	fluorophore:?-?|mutation decreasing interaction:31-31	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0867"(tag visualisation by fluorescence)