#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P61964 uniprotkb:Q7Z3B3 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-740244|uniprotkb:Q6AW85|uniprotkb:Q8IYH1|uniprotkb:Q9BRH0|uniprotkb:Q9NTE7|uniprotkb:Q9UFT0|uniprotkb:Q9ULF3|uniprotkb:A8K5E4|ensembl:ENSP00000262419|ensembl:ENSP00000387393|ensembl:ENSP00000461484|ensembl:ENSP00000461812|intact:EBI-10178305|uniprotkb:B3KT49|uniprotkb:I3L4J3 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kanl1_human(display_long)|uniprotkb:KANSL1(gene name)|psi-mi:KANSL1(display_short)|uniprotkb:KIAA1267(gene name synonym)|uniprotkb:MLL1/MLL complex subunit KANSL1(gene name synonym)|uniprotkb:MSL1 homolog 1(gene name synonym)|uniprotkb:MSL1V1(gene name synonym)|uniprotkb:NSL complex protein NSL1(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Non-specific lethal 1 homolog(gene name synonym)|uniprotkb:CENP-36(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9552039|imex:IM-22651-1|rcsb pdb:4CY1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001180394.1|refseq:NP_001180395.1|refseq:NP_056258.1|refseq:XP_006721886.1|ensembl:ENSG00000120071(gene)|ensembl:ENST00000262419(transcript)|ensembl:ENST00000432791(transcript)|ensembl:ENST00000572904(transcript)|ensembl:ENST00000574590(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR026180|interpro:IPR029332|mint:Q7Z3B3|rcsb pdb:4CY1|rcsb pdb:4CY2|reactome:R-HSA-3214847|refseq:XP_006721887.1 - - - figure legend:Table 1|3d-r-factors:working 17.2%, free 18.4%|3d-resolution:1.50A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:Co/MKm4PZcwn3BUf6ZKYOqW0VhA9606 intact-crc:45D50A346B1CFD26|rigid:95MS4kir7YECtzi8jCf3QxTeiLI false sufficient binding region:23-334(IPR001680) sufficient binding region:585-598(LIG_WD40_WDR5_WIN_1)|mutation:599-599 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z3B3 uniprotkb:Q9H9L4 intact:EBI-740244|uniprotkb:Q6AW85|uniprotkb:Q8IYH1|uniprotkb:Q9BRH0|uniprotkb:Q9NTE7|uniprotkb:Q9UFT0|uniprotkb:Q9ULF3|uniprotkb:A8K5E4|ensembl:ENSP00000262419|ensembl:ENSP00000387393|ensembl:ENSP00000461484|ensembl:ENSP00000461812|intact:EBI-10178305|uniprotkb:B3KT49|uniprotkb:I3L4J3 intact:EBI-2560840|uniprotkb:Q8N3B5|uniprotkb:Q9NX51|uniprotkb:Q96CV0|ensembl:ENSP00000415436 psi-mi:kanl1_human(display_long)|uniprotkb:KANSL1(gene name)|psi-mi:KANSL1(display_short)|uniprotkb:KIAA1267(gene name synonym)|uniprotkb:MLL1/MLL complex subunit KANSL1(gene name synonym)|uniprotkb:MSL1 homolog 1(gene name synonym)|uniprotkb:MSL1V1(gene name synonym)|uniprotkb:NSL complex protein NSL1(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Non-specific lethal 1 homolog(gene name synonym)|uniprotkb:CENP-36(gene name synonym) psi-mi:kanl2_human(display_long)|uniprotkb:KANSL2(gene name)|psi-mi:KANSL2(display_short)|uniprotkb:C12orf41(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9630808|imex:IM-22651-2|rcsb pdb:4CY2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180394.1|refseq:NP_001180395.1|refseq:NP_056258.1|refseq:XP_006721886.1|ensembl:ENSG00000120071(gene)|ensembl:ENST00000262419(transcript)|ensembl:ENST00000432791(transcript)|ensembl:ENST00000572904(transcript)|ensembl:ENST00000574590(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR026180|interpro:IPR029332|mint:Q7Z3B3|rcsb pdb:4CY1|rcsb pdb:4CY2|reactome:R-HSA-3214847|refseq:XP_006721887.1 refseq:NP_060292.3|ensembl:ENSG00000139620(gene)|ensembl:ENST00000420613(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|mint:Q9H9L4|rcsb pdb:4CY2|reactome:R-HSA-3214847 - - - figure legend:Table 1|3d-resolution:2.00A|3d-r-factors:working 20.2%, free 22.2%|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:Co/MKm4PZcwn3BUf6ZKYOqW0VhA9606 rogid:ymOXqnaeH6HuGcHPg4R2XVmWAz89606 intact-crc:C98C7F0F1A322F11|rigid:NQ5npu0Mox7jZO8vo/SXQs0k5sU false sufficient binding region:585-598(LIG_WD40_WDR5_WIN_1)|mutation:599-599 sufficient binding region:406-417(LIG_WD40_WDR5_VDV_1)|mutation:405-405 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z3B3 uniprotkb:P61964 intact:EBI-740244|uniprotkb:Q6AW85|uniprotkb:Q8IYH1|uniprotkb:Q9BRH0|uniprotkb:Q9NTE7|uniprotkb:Q9UFT0|uniprotkb:Q9ULF3|uniprotkb:A8K5E4|ensembl:ENSP00000262419|ensembl:ENSP00000387393|ensembl:ENSP00000461484|ensembl:ENSP00000461812|intact:EBI-10178305|uniprotkb:B3KT49|uniprotkb:I3L4J3 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:kanl1_human(display_long)|uniprotkb:KANSL1(gene name)|psi-mi:KANSL1(display_short)|uniprotkb:KIAA1267(gene name synonym)|uniprotkb:MLL1/MLL complex subunit KANSL1(gene name synonym)|uniprotkb:MSL1 homolog 1(gene name synonym)|uniprotkb:MSL1V1(gene name synonym)|uniprotkb:NSL complex protein NSL1(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Non-specific lethal 1 homolog(gene name synonym)|uniprotkb:CENP-36(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9630808|imex:IM-22651-2|rcsb pdb:4CY2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180394.1|refseq:NP_001180395.1|refseq:NP_056258.1|refseq:XP_006721886.1|ensembl:ENSG00000120071(gene)|ensembl:ENST00000262419(transcript)|ensembl:ENST00000432791(transcript)|ensembl:ENST00000572904(transcript)|ensembl:ENST00000574590(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR026180|interpro:IPR029332|mint:Q7Z3B3|rcsb pdb:4CY1|rcsb pdb:4CY2|reactome:R-HSA-3214847|refseq:XP_006721887.1 refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - - figure legend:Table 1|3d-resolution:2.00A|3d-r-factors:working 20.2%, free 22.2%|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:Co/MKm4PZcwn3BUf6ZKYOqW0VhA9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:C98C7F0F1A322F11|rigid:NQ5npu0Mox7jZO8vo/SXQs0k5sU false sufficient binding region:585-598(LIG_WD40_WDR5_WIN_1)|mutation:599-599 sufficient binding region:23-334(IPR001680) 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9V3J8 uniprotkb:A4V2Z1 intact:EBI-90899|ensemblmetazoa:FBpp0070422|ensemblmetazoa:FBpp0300790 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 psi-mi:wds_drome(display_long)|uniprotkb:wds(gene name)|psi-mi:wds(display_short)|uniprotkb:CG17437(orf name)|uniprotkb:"l(1)3Ad"(gene name synonym)|uniprotkb:"l(1)zw8"(gene name synonym) psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:"MI:0114"(x-ray crystallography) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9630825|imex:IM-22651-3|rcsb pdb:4CY3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524984.1|flybase:FBgn0040066|ensemblmetazoa:FBgn0040066(gene)|ensemblmetazoa:FBtr0308566(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0016573"(histone acetylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0044545"(NSL complex)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4CY3|ensemblmetazoa:FBtr0070438(transcript)|rcsb pdb:4CY5|reactome:R-DME-8936459|reactome:R-DME-8951664|refseq:NP_001245503.1 refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - figure legend:Table 1|3d-resolution:1.40A|3d-r-factors:working 18.0%, free 19.0%|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:y/lQewuJ/gHsErsWSIBFTQqfL1U7227 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 intact-crc:33F34CAC648624B6|rigid:5B4ZAA89C5vLdBl57Lhpm27An6c false sufficient binding region:50-361(IPR001680) sufficient binding region:714-729(LIG_WD40_WDR5_WIN_2) 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A4V2Z1 uniprotkb:Q9VAF4 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:"MI:0114"(x-ray crystallography) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9630882|imex:IM-22651-4|rcsb pdb:4CY5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 - - - figure legend:Table 1|3d-resolution:2.30A|3d-r-factors:working 20.8%, free 24.6%|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 intact-crc:BCFA56D572B39DB1|rigid:d4AkiZG8W2+pQvYef/jXFZu+D4s false sufficient binding region:714-729 sufficient binding region:155-166(LIG_WD40_WDR5_VDV_1)|mutation:154-154 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A4V2Z1 uniprotkb:Q9V3J8 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-90899|ensemblmetazoa:FBpp0070422|ensemblmetazoa:FBpp0300790 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:wds_drome(display_long)|uniprotkb:wds(gene name)|psi-mi:wds(display_short)|uniprotkb:CG17437(orf name)|uniprotkb:"l(1)3Ad"(gene name synonym)|uniprotkb:"l(1)zw8"(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9630882|imex:IM-22651-4|rcsb pdb:4CY5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) refseq:NP_524984.1|flybase:FBgn0040066|ensemblmetazoa:FBgn0040066(gene)|ensemblmetazoa:FBtr0308566(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0016573"(histone acetylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0044545"(NSL complex)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4CY3|ensemblmetazoa:FBtr0070438(transcript)|rcsb pdb:4CY5|reactome:R-DME-8936459|reactome:R-DME-8951664|refseq:NP_001245503.1 - - - figure legend:Table 1|3d-resolution:2.30A|3d-r-factors:working 20.8%, free 24.6%|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:y/lQewuJ/gHsErsWSIBFTQqfL1U7227 intact-crc:BCFA56D572B39DB1|rigid:d4AkiZG8W2+pQvYef/jXFZu+D4s false sufficient binding region:714-729 sufficient binding region:50-361(IPR001680) 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61964 uniprotkb:Q7Z3B3 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-740244|uniprotkb:Q6AW85|uniprotkb:Q8IYH1|uniprotkb:Q9BRH0|uniprotkb:Q9NTE7|uniprotkb:Q9UFT0|uniprotkb:Q9ULF3|uniprotkb:A8K5E4|ensembl:ENSP00000262419|ensembl:ENSP00000387393|ensembl:ENSP00000461484|ensembl:ENSP00000461812|intact:EBI-10178305|uniprotkb:B3KT49|uniprotkb:I3L4J3 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kanl1_human(display_long)|uniprotkb:KANSL1(gene name)|psi-mi:KANSL1(display_short)|uniprotkb:KIAA1267(gene name synonym)|uniprotkb:MLL1/MLL complex subunit KANSL1(gene name synonym)|uniprotkb:MSL1 homolog 1(gene name synonym)|uniprotkb:MSL1V1(gene name synonym)|uniprotkb:NSL complex protein NSL1(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Non-specific lethal 1 homolog(gene name synonym)|uniprotkb:CENP-36(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9630923|imex:IM-22651-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001180394.1|refseq:NP_001180395.1|refseq:NP_056258.1|refseq:XP_006721886.1|ensembl:ENSG00000120071(gene)|ensembl:ENST00000262419(transcript)|ensembl:ENST00000432791(transcript)|ensembl:ENST00000572904(transcript)|ensembl:ENST00000574590(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR026180|interpro:IPR029332|mint:Q7Z3B3|rcsb pdb:4CY1|rcsb pdb:4CY2|reactome:R-HSA-3214847|refseq:XP_006721887.1 - - - figure legend:Fig. 1j, Fig. 1k|kinetic_conditions:Temp = 25C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:181.0x10^-9 ~12.0(molar) 2014/06/18 2014/10/16 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:Co/MKm4PZcwn3BUf6ZKYOqW0VhA9606 intact-crc:DE4AEA5503CFC874|rigid:95MS4kir7YECtzi8jCf3QxTeiLI false sufficient binding region:23-334(IPR001680) sufficient binding region:585-598(LIG_WD40_WDR5_WIN_1)|mutation disrupting interaction:592-592|mutation:599-599 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61964 uniprotkb:Q9H9L4 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2560840|uniprotkb:Q8N3B5|uniprotkb:Q9NX51|uniprotkb:Q96CV0|ensembl:ENSP00000415436 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kanl2_human(display_long)|uniprotkb:KANSL2(gene name)|psi-mi:KANSL2(display_short)|uniprotkb:C12orf41(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9630938|imex:IM-22651-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_060292.3|ensembl:ENSG00000139620(gene)|ensembl:ENST00000420613(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|mint:Q9H9L4|rcsb pdb:4CY2|reactome:R-HSA-3214847 - - - figure legend:Fig. 2f, Fig. 2g|kinetic_conditions:Temp = 25C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:8.6x10^-6 ~0.3(molar) 2014/06/18 2014/10/16 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:ymOXqnaeH6HuGcHPg4R2XVmWAz89606 intact-crc:8F221C4EB43AF3F0|rigid:zY171Pab7wK7Zm2B7QpdUdVvmTI false sufficient binding region:23-334(IPR001680) sufficient binding region:406-417(LIG_WD40_WDR5_VDV_1)|mutation:405-405|mutation disrupting interaction:411-411,413-413 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9V3J8 uniprotkb:Q9VAF4 intact:EBI-90899|ensemblmetazoa:FBpp0070422|ensemblmetazoa:FBpp0300790 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 psi-mi:wds_drome(display_long)|uniprotkb:wds(gene name)|psi-mi:wds(display_short)|uniprotkb:CG17437(orf name)|uniprotkb:"l(1)3Ad"(gene name synonym)|uniprotkb:"l(1)zw8"(gene name synonym) psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:"MI:0065"(isothermal titration calorimetry) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9630956|imex:IM-22651-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524984.1|flybase:FBgn0040066|ensemblmetazoa:FBgn0040066(gene)|ensemblmetazoa:FBtr0308566(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0016573"(histone acetylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0044545"(NSL complex)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4CY3|ensemblmetazoa:FBtr0070438(transcript)|rcsb pdb:4CY5|reactome:R-DME-8936459|reactome:R-DME-8951664|refseq:NP_001245503.1 ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 - - - figure legend:Fig. 2h, Fig. 2i|kinetic_conditions:Temp = 25C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:7.3x10^-6 ~0.3(molar) 2014/06/18 2014/10/16 rogid:y/lQewuJ/gHsErsWSIBFTQqfL1U7227 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 intact-crc:09EF6F9C58272C9A|rigid:zgoF2/M3BH/JtC2Oz1g6bMOpmOk false sufficient binding region:50-361(IPR001680) sufficient binding region:155-166(LIG_WD40_WDR5_VDV_1)|mutation:154-154|mutation disrupting interaction:160-160,162-162 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61964 uniprotkb:Q9UMN6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-765774|uniprotkb:O15022|uniprotkb:O95836|uniprotkb:Q96GP2|uniprotkb:Q96IP3|uniprotkb:Q9UK25|uniprotkb:Q9Y668|uniprotkb:Q9Y669|ensembl:ENSP00000398837 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kmt2b_human(display_long)|uniprotkb:KMT2B(gene name)|psi-mi:KMT2B(display_short)|uniprotkb:HRX2(gene name synonym)|uniprotkb:KIAA0304(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 4(gene name synonym)|uniprotkb:TRX2(gene name synonym)|uniprotkb:Trithorax homolog 2(gene name synonym)|uniprotkb:WBP7(gene name synonym)|uniprotkb:WW domain-binding protein 7(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9630974|imex:IM-22651-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N ensembl:ENSP00000398837|dip:DIP-34598N|ensembl:ENSG00000272333(gene)|ensembl:ENST00000420124(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR041959|mint:Q9UMN6|rcsb pdb:3UVM|rcsb pdb:4ERZ|rcsb pdb:4PZI|rcsb pdb:7BRE|reactome:R-HSA-3214841|reactome:R-HSA-8936459 - - - figure legend:Suppl. Fig. S6a|kinetic_conditions:Temp = 25C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:32.0x10^-9 ~1.0(molar) 2014/06/18 2014/10/16 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:1Im1Dqkyg85ZGqrxLaK4wyMVGNY9606 intact-crc:21317121507BC12C|rigid:iJ2KJP25AFhC6NGkMJM9sJEIpOc false sufficient binding region:23-334(IPR001680) sufficient binding region:2504-2518(LIG_WD40_WDR5_WIN_1) 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61964 uniprotkb:Q7Z3B3 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-740244|uniprotkb:Q6AW85|uniprotkb:Q8IYH1|uniprotkb:Q9BRH0|uniprotkb:Q9NTE7|uniprotkb:Q9UFT0|uniprotkb:Q9ULF3|uniprotkb:A8K5E4|ensembl:ENSP00000262419|ensembl:ENSP00000387393|ensembl:ENSP00000461484|ensembl:ENSP00000461812|intact:EBI-10178305|uniprotkb:B3KT49|uniprotkb:I3L4J3 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kanl1_human(display_long)|uniprotkb:KANSL1(gene name)|psi-mi:KANSL1(display_short)|uniprotkb:KIAA1267(gene name synonym)|uniprotkb:MLL1/MLL complex subunit KANSL1(gene name synonym)|uniprotkb:MSL1 homolog 1(gene name synonym)|uniprotkb:MSL1V1(gene name synonym)|uniprotkb:NSL complex protein NSL1(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Non-specific lethal 1 homolog(gene name synonym)|uniprotkb:CENP-36(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9630996|imex:IM-22651-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001180394.1|refseq:NP_001180395.1|refseq:NP_056258.1|refseq:XP_006721886.1|ensembl:ENSG00000120071(gene)|ensembl:ENST00000262419(transcript)|ensembl:ENST00000432791(transcript)|ensembl:ENST00000572904(transcript)|ensembl:ENST00000574590(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR026180|interpro:IPR029332|mint:Q7Z3B3|rcsb pdb:4CY1|rcsb pdb:4CY2|reactome:R-HSA-3214847|refseq:XP_006721887.1 - - - figure legend:Suppl. Fig. S6b|kinetic_conditions:Temp = 25C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:Co/MKm4PZcwn3BUf6ZKYOqW0VhA9606 intact-crc:249098B833B16BF1|rigid:aRjZ6b+T3jdtaB8x1SyguJEbYzE false sufficient binding region:23-334(IPR001680) sufficient binding region:585-598(LIG_WD40_WDR5_WIN_1)|mutation:599-599 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61964 uniprotkb:Q9UMN6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-765774|uniprotkb:O15022|uniprotkb:O95836|uniprotkb:Q96GP2|uniprotkb:Q96IP3|uniprotkb:Q9UK25|uniprotkb:Q9Y668|uniprotkb:Q9Y669|ensembl:ENSP00000398837 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kmt2b_human(display_long)|uniprotkb:KMT2B(gene name)|psi-mi:KMT2B(display_short)|uniprotkb:HRX2(gene name synonym)|uniprotkb:KIAA0304(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 4(gene name synonym)|uniprotkb:TRX2(gene name synonym)|uniprotkb:Trithorax homolog 2(gene name synonym)|uniprotkb:WBP7(gene name synonym)|uniprotkb:WW domain-binding protein 7(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9630996|imex:IM-22651-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N ensembl:ENSP00000398837|dip:DIP-34598N|ensembl:ENSG00000272333(gene)|ensembl:ENST00000420124(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR041959|mint:Q9UMN6|rcsb pdb:3UVM|rcsb pdb:4ERZ|rcsb pdb:4PZI|rcsb pdb:7BRE|reactome:R-HSA-3214841|reactome:R-HSA-8936459 - - - figure legend:Suppl. Fig. S6b|kinetic_conditions:Temp = 25C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:1Im1Dqkyg85ZGqrxLaK4wyMVGNY9606 intact-crc:249098B833B16BF1|rigid:aRjZ6b+T3jdtaB8x1SyguJEbYzE false sufficient binding region:23-334(IPR001680) sufficient binding region:2504-2518(LIG_WD40_WDR5_WIN_1) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P68431 uniprotkb:P61964 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9631171|imex:IM-22651-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - - figure legend:Suppl. Fig. S6c|kinetic_conditions:Temp = 25C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:46.0x10^-6 ~4.0(molar) 2014/06/18 2014/10/16 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:274DAF7F33A2BE6D|rigid:Plf5F21UCJY+Ea/ZURtFfhMFhUs false sufficient binding region:2-11|mutation:11-11 sufficient binding region:23-334(IPR001680) 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61964 uniprotkb:Q7Z3B3 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-740244|uniprotkb:Q6AW85|uniprotkb:Q8IYH1|uniprotkb:Q9BRH0|uniprotkb:Q9NTE7|uniprotkb:Q9UFT0|uniprotkb:Q9ULF3|uniprotkb:A8K5E4|ensembl:ENSP00000262419|ensembl:ENSP00000387393|ensembl:ENSP00000461484|ensembl:ENSP00000461812|intact:EBI-10178305|uniprotkb:B3KT49|uniprotkb:I3L4J3 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kanl1_human(display_long)|uniprotkb:KANSL1(gene name)|psi-mi:KANSL1(display_short)|uniprotkb:KIAA1267(gene name synonym)|uniprotkb:MLL1/MLL complex subunit KANSL1(gene name synonym)|uniprotkb:MSL1 homolog 1(gene name synonym)|uniprotkb:MSL1V1(gene name synonym)|uniprotkb:NSL complex protein NSL1(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Non-specific lethal 1 homolog(gene name synonym)|uniprotkb:CENP-36(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631208|imex:IM-22651-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001180394.1|refseq:NP_001180395.1|refseq:NP_056258.1|refseq:XP_006721886.1|ensembl:ENSG00000120071(gene)|ensembl:ENST00000262419(transcript)|ensembl:ENST00000432791(transcript)|ensembl:ENST00000572904(transcript)|ensembl:ENST00000574590(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR026180|interpro:IPR029332|mint:Q7Z3B3|rcsb pdb:4CY1|rcsb pdb:4CY2|reactome:R-HSA-3214847|refseq:XP_006721887.1 - - - figure legend:Suppl. Fig. S6d|kinetic_conditions:Temp = 25C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:Co/MKm4PZcwn3BUf6ZKYOqW0VhA9606 intact-crc:3FCDAE79E5968544|rigid:rZ8EuVl5UNKJ/wRor1hMBd9YVxY false sufficient binding region:23-334 mutation:599-599|sufficient binding region:585-598(LIG_WD40_WDR5_WIN_1) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61964 uniprotkb:P68431 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631208|imex:IM-22651-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - - - figure legend:Suppl. Fig. S6d|kinetic_conditions:Temp = 25C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 intact-crc:3FCDAE79E5968544|rigid:rZ8EuVl5UNKJ/wRor1hMBd9YVxY false sufficient binding region:23-334 mutation:11-11|sufficient binding region:2-11 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A4V2Z1 uniprotkb:O02193 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-138539|uniprotkb:Q9W463|uniprotkb:A8B845|uniprotkb:A8B850|uniprotkb:A8B854|uniprotkb:A8B859|uniprotkb:A8B879|uniprotkb:A8B889|uniprotkb:A8B895|uniprotkb:A8B8A1|uniprotkb:A8ILB7|uniprotkb:A8ILC1|uniprotkb:A8ILC8|uniprotkb:A8ILD1|uniprotkb:A8ILD6|uniprotkb:A8ILE1|uniprotkb:A8ILE5|ensemblmetazoa:FBpp0070794 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:mof_drome(display_long)|uniprotkb:mof(gene name)|psi-mi:mof(display_short)|uniprotkb:Histone acetyl transferase MOF(gene name synonym)|uniprotkb:CG3025(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631293|imex:IM-22651-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000805"(X chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006281"(DNA repair)|go:"GO:0007549"(dosage compensation)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016456"(X chromosome located dosage compensation complex, transcription activating)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042393"(histone binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072487"(MSL complex)|go:"GO:2000873"(regulation of histone H4 acetylation involved in response to DNA damage stimulus)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037906|interpro:IPR040706|rcsb pdb:2BUD|ensemblmetazoa:FBgn0014340(gene)|ensemblmetazoa:FBtr0070829(transcript)|refseq:NP_511051.1|flybase:FBgn0014340|dip:DIP-46346N - - - figure legend:Fig. 1a, Suppl. Fig. 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:YoHi/N+rxfKrb2CV6iRu+e0BEvs7227 intact-crc:757EB88350974CE5|rigid:li65SRf/vB1jFIpQf8nDUi0sUmU false flag tag:n-n - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q9V3J8 uniprotkb:A4V2Z1 intact:EBI-90899|ensemblmetazoa:FBpp0070422|ensemblmetazoa:FBpp0300790 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 psi-mi:wds_drome(display_long)|uniprotkb:wds(gene name)|psi-mi:wds(display_short)|uniprotkb:CG17437(orf name)|uniprotkb:"l(1)3Ad"(gene name synonym)|uniprotkb:"l(1)zw8"(gene name synonym) psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631300|imex:IM-22651-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524984.1|flybase:FBgn0040066|ensemblmetazoa:FBgn0040066(gene)|ensemblmetazoa:FBtr0308566(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0016573"(histone acetylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0044545"(NSL complex)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4CY3|ensemblmetazoa:FBtr0070438(transcript)|rcsb pdb:4CY5|reactome:R-DME-8936459|reactome:R-DME-8951664|refseq:NP_001245503.1 refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - figure legend:Fig. 1a, Suppl. Fig. 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:y/lQewuJ/gHsErsWSIBFTQqfL1U7227 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 intact-crc:380BC331E615D166|rigid:5B4ZAA89C5vLdBl57Lhpm27An6c false - flag tag:n-n - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:A4V2Z1 uniprotkb:Q9VZJ3 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-168170|ensemblmetazoa:FBpp0073058 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:q9vzj3_drome(display_long)|uniprotkb:Rcd5(gene name)|psi-mi:Rcd5(display_short)|uniprotkb:Dmel\CG1135(gene name synonym)|uniprotkb:MCRS1(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:dMCRS1(gene name synonym)|uniprotkb:dMCRS2(gene name synonym)|uniprotkb:"l(3)r0166"(gene name synonym)|uniprotkb:"l(3)rG166"(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:Dmel_CG1135(orf name)|uniprotkb:CG1135(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631421|imex:IM-22651-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) flybase:FBgn0263832|refseq:NP_647852.1|ensemblmetazoa:FBgn0263832(gene)|ensemblmetazoa:FBtr0073202(transcript)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0007099"(centriole replication)|go:"GO:0031011"(Ino80 complex)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|reactome:R-DME-5689603|reactome:R-DME-5696394 - - - figure legend:Fig. 1a, Suppl. Fig. 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:qPejBkSUFl+4R1spoQC8DELJm3o7227 intact-crc:1AFB2DA03DC2C4FC|rigid:k5BkTg4zrU46KG94sxZjTVZ5srA false flag tag:n-n - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q9VGA4 uniprotkb:A4V2Z1 intact:EBI-134420|ensemblmetazoa:FBpp0082081 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 psi-mi:q9vga4_drome(display_long)|uniprotkb:Dm Tam3(gene name synonym)|uniprotkb:Dmel\CG10042(gene name synonym)|uniprotkb:MBD(gene name synonym)|uniprotkb:MBDR2(gene name synonym)|uniprotkb:Mbdr2(gene name synonym)|uniprotkb:Mbrd2(gene name synonym)|uniprotkb:NSL(gene name synonym)|uniprotkb:TAM3(gene name synonym)|uniprotkb:dMBD-R2(gene name synonym)|uniprotkb:mbd-R2(gene name synonym)|uniprotkb:Dmel_CG10042(orf name)|uniprotkb:MBD-R2(gene name)|psi-mi:MBD-R2(display_short)|uniprotkb:CG17393(gene name synonym)|uniprotkb:CG10042(orf name) psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631747|imex:IM-22651-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_731688.2|flybase:FBgn0038016|ensemblmetazoa:FBgn0038016(gene)|ensemblmetazoa:FBtr0082611(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035327"|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR019786|interpro:IPR038441|interpro:IPR043449|reactome:R-DME-6804759 refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - figure legend:Fig. 1a, Suppl. Fig. 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:PSG4AsiVb879jORPcrjqUrGG3jg7227 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 intact-crc:E4D24CA750EB2618|rigid:vDHZ4yjsGvt4V6I09vQ5vYn0M3I false - flag tag:n-n - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q9V3J8 uniprotkb:A4V2Z1 intact:EBI-90899|ensemblmetazoa:FBpp0070422|ensemblmetazoa:FBpp0300790 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 psi-mi:wds_drome(display_long)|uniprotkb:wds(gene name)|psi-mi:wds(display_short)|uniprotkb:CG17437(orf name)|uniprotkb:"l(1)3Ad"(gene name synonym)|uniprotkb:"l(1)zw8"(gene name synonym) psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631816|imex:IM-22651-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524984.1|flybase:FBgn0040066|ensemblmetazoa:FBgn0040066(gene)|ensemblmetazoa:FBtr0308566(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0016573"(histone acetylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0044545"(NSL complex)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4CY3|ensemblmetazoa:FBtr0070438(transcript)|rcsb pdb:4CY5|reactome:R-DME-8936459|reactome:R-DME-8951664|refseq:NP_001245503.1 refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - figure legend:Fig. 1c, Suppl. Fig. 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:y/lQewuJ/gHsErsWSIBFTQqfL1U7227 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 intact-crc:73B628A6387BC912|rigid:5B4ZAA89C5vLdBl57Lhpm27An6c false flag tag:n-n - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q9V3J8 uniprotkb:Q9VAF4 intact:EBI-90899|ensemblmetazoa:FBpp0070422|ensemblmetazoa:FBpp0300790 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 psi-mi:wds_drome(display_long)|uniprotkb:wds(gene name)|psi-mi:wds(display_short)|uniprotkb:CG17437(orf name)|uniprotkb:"l(1)3Ad"(gene name synonym)|uniprotkb:"l(1)zw8"(gene name synonym) psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631823|imex:IM-22651-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524984.1|flybase:FBgn0040066|ensemblmetazoa:FBgn0040066(gene)|ensemblmetazoa:FBtr0308566(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0016573"(histone acetylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0044545"(NSL complex)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4CY3|ensemblmetazoa:FBtr0070438(transcript)|rcsb pdb:4CY5|reactome:R-DME-8936459|reactome:R-DME-8951664|refseq:NP_001245503.1 ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 - - - figure legend:Fig. 1c, Suppl. Fig. 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:y/lQewuJ/gHsErsWSIBFTQqfL1U7227 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 intact-crc:40918E2202A40CA6|rigid:zgoF2/M3BH/JtC2Oz1g6bMOpmOk false flag tag:n-n - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:A4V2Z1 uniprotkb:Q9VGA4 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-134420|ensemblmetazoa:FBpp0082081 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:q9vga4_drome(display_long)|uniprotkb:Dm Tam3(gene name synonym)|uniprotkb:Dmel\CG10042(gene name synonym)|uniprotkb:MBD(gene name synonym)|uniprotkb:MBDR2(gene name synonym)|uniprotkb:Mbdr2(gene name synonym)|uniprotkb:Mbrd2(gene name synonym)|uniprotkb:NSL(gene name synonym)|uniprotkb:TAM3(gene name synonym)|uniprotkb:dMBD-R2(gene name synonym)|uniprotkb:mbd-R2(gene name synonym)|uniprotkb:Dmel_CG10042(orf name)|uniprotkb:MBD-R2(gene name)|psi-mi:MBD-R2(display_short)|uniprotkb:CG17393(gene name synonym)|uniprotkb:CG10042(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631764|imex:IM-22651-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) refseq:NP_731688.2|flybase:FBgn0038016|ensemblmetazoa:FBgn0038016(gene)|ensemblmetazoa:FBtr0082611(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035327"|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR019786|interpro:IPR038441|interpro:IPR043449|reactome:R-DME-6804759 - - - figure legend:Fig. 1b, Suppl. Fig. 1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:PSG4AsiVb879jORPcrjqUrGG3jg7227 intact-crc:87A998BA83990275|rigid:vDHZ4yjsGvt4V6I09vQ5vYn0M3I false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VGA4 uniprotkb:A4V2Z1 intact:EBI-134420|ensemblmetazoa:FBpp0082081 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 psi-mi:q9vga4_drome(display_long)|uniprotkb:Dm Tam3(gene name synonym)|uniprotkb:Dmel\CG10042(gene name synonym)|uniprotkb:MBD(gene name synonym)|uniprotkb:MBDR2(gene name synonym)|uniprotkb:Mbdr2(gene name synonym)|uniprotkb:Mbrd2(gene name synonym)|uniprotkb:NSL(gene name synonym)|uniprotkb:TAM3(gene name synonym)|uniprotkb:dMBD-R2(gene name synonym)|uniprotkb:mbd-R2(gene name synonym)|uniprotkb:Dmel_CG10042(orf name)|uniprotkb:MBD-R2(gene name)|psi-mi:MBD-R2(display_short)|uniprotkb:CG17393(gene name synonym)|uniprotkb:CG10042(orf name) psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631770|imex:IM-22651-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_731688.2|flybase:FBgn0038016|ensemblmetazoa:FBgn0038016(gene)|ensemblmetazoa:FBtr0082611(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035327"|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR019786|interpro:IPR038441|interpro:IPR043449|reactome:R-DME-6804759 refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - figure legend:Fig. 1b, Suppl. Fig. 1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:PSG4AsiVb879jORPcrjqUrGG3jg7227 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 intact-crc:D40F0F790376197E|rigid:vDHZ4yjsGvt4V6I09vQ5vYn0M3I false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A4V2Z1 uniprotkb:Q9VZJ3 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-168170|ensemblmetazoa:FBpp0073058 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:q9vzj3_drome(display_long)|uniprotkb:Rcd5(gene name)|psi-mi:Rcd5(display_short)|uniprotkb:Dmel\CG1135(gene name synonym)|uniprotkb:MCRS1(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:dMCRS1(gene name synonym)|uniprotkb:dMCRS2(gene name synonym)|uniprotkb:"l(3)r0166"(gene name synonym)|uniprotkb:"l(3)rG166"(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:Dmel_CG1135(orf name)|uniprotkb:CG1135(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631778|imex:IM-22651-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) flybase:FBgn0263832|refseq:NP_647852.1|ensemblmetazoa:FBgn0263832(gene)|ensemblmetazoa:FBtr0073202(transcript)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0007099"(centriole replication)|go:"GO:0031011"(Ino80 complex)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|reactome:R-DME-5689603|reactome:R-DME-5696394 - - - figure legend:Fig. 1b, Suppl. Fig. 1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:qPejBkSUFl+4R1spoQC8DELJm3o7227 intact-crc:7980F9BDEEB0E091|rigid:k5BkTg4zrU46KG94sxZjTVZ5srA false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A4V2Z1 uniprotkb:Q9VZJ3 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-168170|ensemblmetazoa:FBpp0073058 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:q9vzj3_drome(display_long)|uniprotkb:Rcd5(gene name)|psi-mi:Rcd5(display_short)|uniprotkb:Dmel\CG1135(gene name synonym)|uniprotkb:MCRS1(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:dMCRS1(gene name synonym)|uniprotkb:dMCRS2(gene name synonym)|uniprotkb:"l(3)r0166"(gene name synonym)|uniprotkb:"l(3)rG166"(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:Dmel_CG1135(orf name)|uniprotkb:CG1135(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631788|imex:IM-22651-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) flybase:FBgn0263832|refseq:NP_647852.1|ensemblmetazoa:FBgn0263832(gene)|ensemblmetazoa:FBtr0073202(transcript)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0007099"(centriole replication)|go:"GO:0031011"(Ino80 complex)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|reactome:R-DME-5689603|reactome:R-DME-5696394 - - - figure legend:Fig. 1b, Suppl. Fig. 1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:qPejBkSUFl+4R1spoQC8DELJm3o7227 intact-crc:FCDD6385320FAAAA|rigid:k5BkTg4zrU46KG94sxZjTVZ5srA false - flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O02193 uniprotkb:A4V2Z1 intact:EBI-138539|uniprotkb:Q9W463|uniprotkb:A8B845|uniprotkb:A8B850|uniprotkb:A8B854|uniprotkb:A8B859|uniprotkb:A8B879|uniprotkb:A8B889|uniprotkb:A8B895|uniprotkb:A8B8A1|uniprotkb:A8ILB7|uniprotkb:A8ILC1|uniprotkb:A8ILC8|uniprotkb:A8ILD1|uniprotkb:A8ILD6|uniprotkb:A8ILE1|uniprotkb:A8ILE5|ensemblmetazoa:FBpp0070794 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 psi-mi:mof_drome(display_long)|uniprotkb:mof(gene name)|psi-mi:mof(display_short)|uniprotkb:Histone acetyl transferase MOF(gene name synonym)|uniprotkb:CG3025(orf name) psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9637335|imex:IM-22651-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000805"(X chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006281"(DNA repair)|go:"GO:0007549"(dosage compensation)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016456"(X chromosome located dosage compensation complex, transcription activating)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042393"(histone binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072487"(MSL complex)|go:"GO:2000873"(regulation of histone H4 acetylation involved in response to DNA damage stimulus)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037906|interpro:IPR040706|rcsb pdb:2BUD|ensemblmetazoa:FBgn0014340(gene)|ensemblmetazoa:FBtr0070829(transcript)|refseq:NP_511051.1|flybase:FBgn0014340|dip:DIP-46346N refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - figure legend:Fig. 1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:YoHi/N+rxfKrb2CV6iRu+e0BEvs7227 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 intact-crc:D23330E509FBF209|rigid:li65SRf/vB1jFIpQf8nDUi0sUmU false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V3J8 uniprotkb:A4V2Z1 intact:EBI-90899|ensemblmetazoa:FBpp0070422|ensemblmetazoa:FBpp0300790 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 psi-mi:wds_drome(display_long)|uniprotkb:wds(gene name)|psi-mi:wds(display_short)|uniprotkb:CG17437(orf name)|uniprotkb:"l(1)3Ad"(gene name synonym)|uniprotkb:"l(1)zw8"(gene name synonym) psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631804|imex:IM-22651-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524984.1|flybase:FBgn0040066|ensemblmetazoa:FBgn0040066(gene)|ensemblmetazoa:FBtr0308566(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0016573"(histone acetylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0044545"(NSL complex)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4CY3|ensemblmetazoa:FBtr0070438(transcript)|rcsb pdb:4CY5|reactome:R-DME-8936459|reactome:R-DME-8951664|refseq:NP_001245503.1 refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - figure legend:Fig. 1b, Suppl. Fig. 1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:y/lQewuJ/gHsErsWSIBFTQqfL1U7227 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 intact-crc:D52194D6FF2587BF|rigid:5B4ZAA89C5vLdBl57Lhpm27An6c false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A4V2Z1 uniprotkb:Q9V3J8 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-90899|ensemblmetazoa:FBpp0070422|ensemblmetazoa:FBpp0300790 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:wds_drome(display_long)|uniprotkb:wds(gene name)|psi-mi:wds(display_short)|uniprotkb:CG17437(orf name)|uniprotkb:"l(1)3Ad"(gene name synonym)|uniprotkb:"l(1)zw8"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631797|imex:IM-22651-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) refseq:NP_524984.1|flybase:FBgn0040066|ensemblmetazoa:FBgn0040066(gene)|ensemblmetazoa:FBtr0308566(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0016573"(histone acetylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0044545"(NSL complex)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4CY3|ensemblmetazoa:FBtr0070438(transcript)|rcsb pdb:4CY5|reactome:R-DME-8936459|reactome:R-DME-8951664|refseq:NP_001245503.1 - - - figure legend:Fig. 1b, Suppl. Fig. 1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:y/lQewuJ/gHsErsWSIBFTQqfL1U7227 intact-crc:5B70172C3567F50B|rigid:5B4ZAA89C5vLdBl57Lhpm27An6c false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VAF4 uniprotkb:Q9VZJ3 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 intact:EBI-168170|ensemblmetazoa:FBpp0073058 psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:q9vzj3_drome(display_long)|uniprotkb:Rcd5(gene name)|psi-mi:Rcd5(display_short)|uniprotkb:Dmel\CG1135(gene name synonym)|uniprotkb:MCRS1(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:dMCRS1(gene name synonym)|uniprotkb:dMCRS2(gene name synonym)|uniprotkb:"l(3)r0166"(gene name synonym)|uniprotkb:"l(3)rG166"(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:Dmel_CG1135(orf name)|uniprotkb:CG1135(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631862|imex:IM-22651-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 flybase:FBgn0263832|refseq:NP_647852.1|ensemblmetazoa:FBgn0263832(gene)|ensemblmetazoa:FBtr0073202(transcript)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0007099"(centriole replication)|go:"GO:0031011"(Ino80 complex)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|reactome:R-DME-5689603|reactome:R-DME-5696394 - - - figure legend:Fig. 3e, Suppl. Fig. S1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 rogid:qPejBkSUFl+4R1spoQC8DELJm3o7227 intact-crc:6CBAF7BD57D15947|rigid:m0+mM7U9vGq2q3cHozicsMtieTA false - flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VZJ3 uniprotkb:Q9VAF4 intact:EBI-168170|ensemblmetazoa:FBpp0073058 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 psi-mi:q9vzj3_drome(display_long)|uniprotkb:Rcd5(gene name)|psi-mi:Rcd5(display_short)|uniprotkb:Dmel\CG1135(gene name synonym)|uniprotkb:MCRS1(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:dMCRS1(gene name synonym)|uniprotkb:dMCRS2(gene name synonym)|uniprotkb:"l(3)r0166"(gene name synonym)|uniprotkb:"l(3)rG166"(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:Dmel_CG1135(orf name)|uniprotkb:CG1135(orf name) psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631854|imex:IM-22651-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0263832|refseq:NP_647852.1|ensemblmetazoa:FBgn0263832(gene)|ensemblmetazoa:FBtr0073202(transcript)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0007099"(centriole replication)|go:"GO:0031011"(Ino80 complex)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|reactome:R-DME-5689603|reactome:R-DME-5696394 ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 - - - figure legend:Fig. 3e, Suppl. Fig. S1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:qPejBkSUFl+4R1spoQC8DELJm3o7227 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 intact-crc:F5F01A0D890A3742|rigid:m0+mM7U9vGq2q3cHozicsMtieTA false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V3J8 uniprotkb:Q9VAF4 intact:EBI-90899|ensemblmetazoa:FBpp0070422|ensemblmetazoa:FBpp0300790 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 psi-mi:wds_drome(display_long)|uniprotkb:wds(gene name)|psi-mi:wds(display_short)|uniprotkb:CG17437(orf name)|uniprotkb:"l(1)3Ad"(gene name synonym)|uniprotkb:"l(1)zw8"(gene name synonym) psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631871|imex:IM-22651-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524984.1|flybase:FBgn0040066|ensemblmetazoa:FBgn0040066(gene)|ensemblmetazoa:FBtr0308566(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0016573"(histone acetylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0044545"(NSL complex)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4CY3|ensemblmetazoa:FBtr0070438(transcript)|rcsb pdb:4CY5|reactome:R-DME-8936459|reactome:R-DME-8951664|refseq:NP_001245503.1 ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 - - - figure legend:Fig. 3e, Suppl. Fig. S1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:y/lQewuJ/gHsErsWSIBFTQqfL1U7227 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 intact-crc:B6AEA70D2EEFB830|rigid:zgoF2/M3BH/JtC2Oz1g6bMOpmOk false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V3J8 uniprotkb:Q9VAF4 intact:EBI-90899|ensemblmetazoa:FBpp0070422|ensemblmetazoa:FBpp0300790 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 psi-mi:wds_drome(display_long)|uniprotkb:wds(gene name)|psi-mi:wds(display_short)|uniprotkb:CG17437(orf name)|uniprotkb:"l(1)3Ad"(gene name synonym)|uniprotkb:"l(1)zw8"(gene name synonym) psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631878|imex:IM-22651-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524984.1|flybase:FBgn0040066|ensemblmetazoa:FBgn0040066(gene)|ensemblmetazoa:FBtr0308566(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0016573"(histone acetylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0044545"(NSL complex)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4CY3|ensemblmetazoa:FBtr0070438(transcript)|rcsb pdb:4CY5|reactome:R-DME-8936459|reactome:R-DME-8951664|refseq:NP_001245503.1 ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 - - - figure legend:Fig. 3e, Suppl. Fig. S1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:y/lQewuJ/gHsErsWSIBFTQqfL1U7227 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 intact-crc:3E54FE7C98FC71F9|rigid:zgoF2/M3BH/JtC2Oz1g6bMOpmOk false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z3B3 uniprotkb:P61964 intact:EBI-740244|uniprotkb:Q6AW85|uniprotkb:Q8IYH1|uniprotkb:Q9BRH0|uniprotkb:Q9NTE7|uniprotkb:Q9UFT0|uniprotkb:Q9ULF3|uniprotkb:A8K5E4|ensembl:ENSP00000262419|ensembl:ENSP00000387393|ensembl:ENSP00000461484|ensembl:ENSP00000461812|intact:EBI-10178305|uniprotkb:B3KT49|uniprotkb:I3L4J3 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:kanl1_human(display_long)|uniprotkb:KANSL1(gene name)|psi-mi:KANSL1(display_short)|uniprotkb:KIAA1267(gene name synonym)|uniprotkb:MLL1/MLL complex subunit KANSL1(gene name synonym)|uniprotkb:MSL1 homolog 1(gene name synonym)|uniprotkb:MSL1V1(gene name synonym)|uniprotkb:NSL complex protein NSL1(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Non-specific lethal 1 homolog(gene name synonym)|uniprotkb:CENP-36(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0096"(pull down) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631841|imex:IM-22651-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180394.1|refseq:NP_001180395.1|refseq:NP_056258.1|refseq:XP_006721886.1|ensembl:ENSG00000120071(gene)|ensembl:ENST00000262419(transcript)|ensembl:ENST00000432791(transcript)|ensembl:ENST00000572904(transcript)|ensembl:ENST00000574590(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR026180|interpro:IPR029332|mint:Q7Z3B3|rcsb pdb:4CY1|rcsb pdb:4CY2|reactome:R-HSA-3214847|refseq:XP_006721887.1 refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - - figure legend:Fig. 1i|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:Co/MKm4PZcwn3BUf6ZKYOqW0VhA9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:EEF9EA89F63A08EF|rigid:95MS4kir7YECtzi8jCf3QxTeiLI false his tag:n-n|mutation disrupting interaction:592-592|sufficient binding region:584-690 sufficient binding region:23-334(IPR001680) - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q7Z3B3 uniprotkb:P61964 intact:EBI-740244|uniprotkb:Q6AW85|uniprotkb:Q8IYH1|uniprotkb:Q9BRH0|uniprotkb:Q9NTE7|uniprotkb:Q9UFT0|uniprotkb:Q9ULF3|uniprotkb:A8K5E4|ensembl:ENSP00000262419|ensembl:ENSP00000387393|ensembl:ENSP00000461484|ensembl:ENSP00000461812|intact:EBI-10178305|uniprotkb:B3KT49|uniprotkb:I3L4J3 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:kanl1_human(display_long)|uniprotkb:KANSL1(gene name)|psi-mi:KANSL1(display_short)|uniprotkb:KIAA1267(gene name synonym)|uniprotkb:MLL1/MLL complex subunit KANSL1(gene name synonym)|uniprotkb:MSL1 homolog 1(gene name synonym)|uniprotkb:MSL1V1(gene name synonym)|uniprotkb:NSL complex protein NSL1(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Non-specific lethal 1 homolog(gene name synonym)|uniprotkb:CENP-36(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0096"(pull down) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632299|imex:IM-22651-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180394.1|refseq:NP_001180395.1|refseq:NP_056258.1|refseq:XP_006721886.1|ensembl:ENSG00000120071(gene)|ensembl:ENST00000262419(transcript)|ensembl:ENST00000432791(transcript)|ensembl:ENST00000572904(transcript)|ensembl:ENST00000574590(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR026180|interpro:IPR029332|mint:Q7Z3B3|rcsb pdb:4CY1|rcsb pdb:4CY2|reactome:R-HSA-3214847|refseq:XP_006721887.1 refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - - figure legend:Suppl. Fig. S2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:Co/MKm4PZcwn3BUf6ZKYOqW0VhA9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:A97FA40B5492467F|rigid:95MS4kir7YECtzi8jCf3QxTeiLI false sufficient binding region:537-773 his tag:n-n|sufficient binding region:23-334(IPR001680) - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q9V3J8 uniprotkb:A4V2Z1 intact:EBI-90899|ensemblmetazoa:FBpp0070422|ensemblmetazoa:FBpp0300790 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 psi-mi:wds_drome(display_long)|uniprotkb:wds(gene name)|psi-mi:wds(display_short)|uniprotkb:CG17437(orf name)|uniprotkb:"l(1)3Ad"(gene name synonym)|uniprotkb:"l(1)zw8"(gene name synonym) psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631895|imex:IM-22651-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524984.1|flybase:FBgn0040066|ensemblmetazoa:FBgn0040066(gene)|ensemblmetazoa:FBtr0308566(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0016573"(histone acetylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0044545"(NSL complex)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4CY3|ensemblmetazoa:FBtr0070438(transcript)|rcsb pdb:4CY5|reactome:R-DME-8936459|reactome:R-DME-8951664|refseq:NP_001245503.1 refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - figure legend:Fig. 1l|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells) - 2014/06/18 2014/10/16 rogid:y/lQewuJ/gHsErsWSIBFTQqfL1U7227 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 intact-crc:21C8EFC0B753A78E|rigid:5B4ZAA89C5vLdBl57Lhpm27An6c false flag tag:n-n mutation disrupting interaction:721-721 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A4V2Z1 uniprotkb:Q8T076 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-3404081|ensemblmetazoa:FBpp0086709 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:q8t076_drome(display_long)|uniprotkb:Dmel\CG8233(gene name synonym)|uniprotkb:NSL3(gene name synonym)|uniprotkb:Nsl3(gene name synonym)|uniprotkb:cg8233(gene name synonym)|uniprotkb:CG8233(orf name)|uniprotkb:Dmel_CG8233(orf name)|uniprotkb:Rcd1(gene name)|psi-mi:Rcd1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631934|imex:IM-22651-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) ensemblmetazoa:FBgn0033897(gene)|ensemblmetazoa:FBtr0087583(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007099"(centriole replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR026555|interpro:IPR029058|flybase:FBgn0033897|refseq:NP_610927.3 - - - figure legend:Fig. 3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:f1DkJOnV2ocyDS2fdoWT+G98fQc7227 intact-crc:A6499CB6584E8E9A|rigid:Cc+sNdAKXzE8ZnlwvUcjbCjRcsY false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A4V2Z1 uniprotkb:Q9V3J8 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-90899|ensemblmetazoa:FBpp0070422|ensemblmetazoa:FBpp0300790 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:wds_drome(display_long)|uniprotkb:wds(gene name)|psi-mi:wds(display_short)|uniprotkb:CG17437(orf name)|uniprotkb:"l(1)3Ad"(gene name synonym)|uniprotkb:"l(1)zw8"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631934|imex:IM-22651-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) refseq:NP_524984.1|flybase:FBgn0040066|ensemblmetazoa:FBgn0040066(gene)|ensemblmetazoa:FBtr0308566(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0016573"(histone acetylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0044545"(NSL complex)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4CY3|ensemblmetazoa:FBtr0070438(transcript)|rcsb pdb:4CY5|reactome:R-DME-8936459|reactome:R-DME-8951664|refseq:NP_001245503.1 - - - figure legend:Fig. 3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:y/lQewuJ/gHsErsWSIBFTQqfL1U7227 intact-crc:A6499CB6584E8E9A|rigid:Cc+sNdAKXzE8ZnlwvUcjbCjRcsY false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A4V2Z1 uniprotkb:Q9VAF4 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631934|imex:IM-22651-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 - - - figure legend:Fig. 3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 intact-crc:A6499CB6584E8E9A|rigid:Cc+sNdAKXzE8ZnlwvUcjbCjRcsY false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A4V2Z1 uniprotkb:Q9VZJ3 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-168170|ensemblmetazoa:FBpp0073058 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:q9vzj3_drome(display_long)|uniprotkb:Rcd5(gene name)|psi-mi:Rcd5(display_short)|uniprotkb:Dmel\CG1135(gene name synonym)|uniprotkb:MCRS1(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:dMCRS1(gene name synonym)|uniprotkb:dMCRS2(gene name synonym)|uniprotkb:"l(3)r0166"(gene name synonym)|uniprotkb:"l(3)rG166"(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:Dmel_CG1135(orf name)|uniprotkb:CG1135(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631934|imex:IM-22651-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) flybase:FBgn0263832|refseq:NP_647852.1|ensemblmetazoa:FBgn0263832(gene)|ensemblmetazoa:FBtr0073202(transcript)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0007099"(centriole replication)|go:"GO:0031011"(Ino80 complex)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|reactome:R-DME-5689603|reactome:R-DME-5696394 - - - figure legend:Fig. 3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:qPejBkSUFl+4R1spoQC8DELJm3o7227 intact-crc:A6499CB6584E8E9A|rigid:Cc+sNdAKXzE8ZnlwvUcjbCjRcsY false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A4V2Z1 uniprotkb:Q9VGA4 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-134420|ensemblmetazoa:FBpp0082081 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:q9vga4_drome(display_long)|uniprotkb:Dm Tam3(gene name synonym)|uniprotkb:Dmel\CG10042(gene name synonym)|uniprotkb:MBD(gene name synonym)|uniprotkb:MBDR2(gene name synonym)|uniprotkb:Mbdr2(gene name synonym)|uniprotkb:Mbrd2(gene name synonym)|uniprotkb:NSL(gene name synonym)|uniprotkb:TAM3(gene name synonym)|uniprotkb:dMBD-R2(gene name synonym)|uniprotkb:mbd-R2(gene name synonym)|uniprotkb:Dmel_CG10042(orf name)|uniprotkb:MBD-R2(gene name)|psi-mi:MBD-R2(display_short)|uniprotkb:CG17393(gene name synonym)|uniprotkb:CG10042(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631934|imex:IM-22651-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) refseq:NP_731688.2|flybase:FBgn0038016|ensemblmetazoa:FBgn0038016(gene)|ensemblmetazoa:FBtr0082611(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035327"|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR019786|interpro:IPR038441|interpro:IPR043449|reactome:R-DME-6804759 - - - figure legend:Fig. 3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:PSG4AsiVb879jORPcrjqUrGG3jg7227 intact-crc:A6499CB6584E8E9A|rigid:Cc+sNdAKXzE8ZnlwvUcjbCjRcsY false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A4V2Z1 uniprotkb:O02193 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-138539|uniprotkb:Q9W463|uniprotkb:A8B845|uniprotkb:A8B850|uniprotkb:A8B854|uniprotkb:A8B859|uniprotkb:A8B879|uniprotkb:A8B889|uniprotkb:A8B895|uniprotkb:A8B8A1|uniprotkb:A8ILB7|uniprotkb:A8ILC1|uniprotkb:A8ILC8|uniprotkb:A8ILD1|uniprotkb:A8ILD6|uniprotkb:A8ILE1|uniprotkb:A8ILE5|ensemblmetazoa:FBpp0070794 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:mof_drome(display_long)|uniprotkb:mof(gene name)|psi-mi:mof(display_short)|uniprotkb:Histone acetyl transferase MOF(gene name synonym)|uniprotkb:CG3025(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631934|imex:IM-22651-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000805"(X chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006281"(DNA repair)|go:"GO:0007549"(dosage compensation)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016456"(X chromosome located dosage compensation complex, transcription activating)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042393"(histone binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072487"(MSL complex)|go:"GO:2000873"(regulation of histone H4 acetylation involved in response to DNA damage stimulus)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037906|interpro:IPR040706|rcsb pdb:2BUD|ensemblmetazoa:FBgn0014340(gene)|ensemblmetazoa:FBtr0070829(transcript)|refseq:NP_511051.1|flybase:FBgn0014340|dip:DIP-46346N - - - figure legend:Fig. 3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:YoHi/N+rxfKrb2CV6iRu+e0BEvs7227 intact-crc:A6499CB6584E8E9A|rigid:Cc+sNdAKXzE8ZnlwvUcjbCjRcsY false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A4V2Z1 uniprotkb:Q9VGA4 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-134420|ensemblmetazoa:FBpp0082081 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:q9vga4_drome(display_long)|uniprotkb:Dm Tam3(gene name synonym)|uniprotkb:Dmel\CG10042(gene name synonym)|uniprotkb:MBD(gene name synonym)|uniprotkb:MBDR2(gene name synonym)|uniprotkb:Mbdr2(gene name synonym)|uniprotkb:Mbrd2(gene name synonym)|uniprotkb:NSL(gene name synonym)|uniprotkb:TAM3(gene name synonym)|uniprotkb:dMBD-R2(gene name synonym)|uniprotkb:mbd-R2(gene name synonym)|uniprotkb:Dmel_CG10042(orf name)|uniprotkb:MBD-R2(gene name)|psi-mi:MBD-R2(display_short)|uniprotkb:CG17393(gene name synonym)|uniprotkb:CG10042(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631946|imex:IM-22651-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) refseq:NP_731688.2|flybase:FBgn0038016|ensemblmetazoa:FBgn0038016(gene)|ensemblmetazoa:FBtr0082611(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035327"|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR019786|interpro:IPR038441|interpro:IPR043449|reactome:R-DME-6804759 - - - figure legend:Fig. 3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:PSG4AsiVb879jORPcrjqUrGG3jg7227 intact-crc:EF7C8C7F9EDE6750|rigid:js09afZM9N7q2goBKpFJXQc6nXc false flag tag:?-?|mutation:721-721 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A4V2Z1 uniprotkb:O02193 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-138539|uniprotkb:Q9W463|uniprotkb:A8B845|uniprotkb:A8B850|uniprotkb:A8B854|uniprotkb:A8B859|uniprotkb:A8B879|uniprotkb:A8B889|uniprotkb:A8B895|uniprotkb:A8B8A1|uniprotkb:A8ILB7|uniprotkb:A8ILC1|uniprotkb:A8ILC8|uniprotkb:A8ILD1|uniprotkb:A8ILD6|uniprotkb:A8ILE1|uniprotkb:A8ILE5|ensemblmetazoa:FBpp0070794 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:mof_drome(display_long)|uniprotkb:mof(gene name)|psi-mi:mof(display_short)|uniprotkb:Histone acetyl transferase MOF(gene name synonym)|uniprotkb:CG3025(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631946|imex:IM-22651-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000805"(X chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006281"(DNA repair)|go:"GO:0007549"(dosage compensation)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016456"(X chromosome located dosage compensation complex, transcription activating)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042393"(histone binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072487"(MSL complex)|go:"GO:2000873"(regulation of histone H4 acetylation involved in response to DNA damage stimulus)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037906|interpro:IPR040706|rcsb pdb:2BUD|ensemblmetazoa:FBgn0014340(gene)|ensemblmetazoa:FBtr0070829(transcript)|refseq:NP_511051.1|flybase:FBgn0014340|dip:DIP-46346N - - - figure legend:Fig. 3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:YoHi/N+rxfKrb2CV6iRu+e0BEvs7227 intact-crc:EF7C8C7F9EDE6750|rigid:js09afZM9N7q2goBKpFJXQc6nXc false flag tag:?-?|mutation:721-721 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A4V2Z1 uniprotkb:Q9VZJ3 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-168170|ensemblmetazoa:FBpp0073058 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:q9vzj3_drome(display_long)|uniprotkb:Rcd5(gene name)|psi-mi:Rcd5(display_short)|uniprotkb:Dmel\CG1135(gene name synonym)|uniprotkb:MCRS1(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:dMCRS1(gene name synonym)|uniprotkb:dMCRS2(gene name synonym)|uniprotkb:"l(3)r0166"(gene name synonym)|uniprotkb:"l(3)rG166"(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:Dmel_CG1135(orf name)|uniprotkb:CG1135(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631946|imex:IM-22651-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) flybase:FBgn0263832|refseq:NP_647852.1|ensemblmetazoa:FBgn0263832(gene)|ensemblmetazoa:FBtr0073202(transcript)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0007099"(centriole replication)|go:"GO:0031011"(Ino80 complex)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|reactome:R-DME-5689603|reactome:R-DME-5696394 - - - figure legend:Fig. 3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:qPejBkSUFl+4R1spoQC8DELJm3o7227 intact-crc:EF7C8C7F9EDE6750|rigid:js09afZM9N7q2goBKpFJXQc6nXc false flag tag:?-?|mutation:721-721 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A4V2Z1 uniprotkb:Q9VAF4 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631946|imex:IM-22651-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 - - - figure legend:Fig. 3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 intact-crc:EF7C8C7F9EDE6750|rigid:js09afZM9N7q2goBKpFJXQc6nXc false flag tag:?-?|mutation:721-721 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VAF4 uniprotkb:Q9V3J8 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 intact:EBI-90899|ensemblmetazoa:FBpp0070422|ensemblmetazoa:FBpp0300790 psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:wds_drome(display_long)|uniprotkb:wds(gene name)|psi-mi:wds(display_short)|uniprotkb:CG17437(orf name)|uniprotkb:"l(1)3Ad"(gene name synonym)|uniprotkb:"l(1)zw8"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631967|imex:IM-22651-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 refseq:NP_524984.1|flybase:FBgn0040066|ensemblmetazoa:FBgn0040066(gene)|ensemblmetazoa:FBtr0308566(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0016573"(histone acetylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0044545"(NSL complex)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4CY3|ensemblmetazoa:FBtr0070438(transcript)|rcsb pdb:4CY5|reactome:R-DME-8936459|reactome:R-DME-8951664|refseq:NP_001245503.1 - - - figure legend:Fig. 3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 rogid:y/lQewuJ/gHsErsWSIBFTQqfL1U7227 intact-crc:9277AC5AC89EC1F3|rigid:Cc+sNdAKXzE8ZnlwvUcjbCjRcsY false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VAF4 uniprotkb:O02193 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 intact:EBI-138539|uniprotkb:Q9W463|uniprotkb:A8B845|uniprotkb:A8B850|uniprotkb:A8B854|uniprotkb:A8B859|uniprotkb:A8B879|uniprotkb:A8B889|uniprotkb:A8B895|uniprotkb:A8B8A1|uniprotkb:A8ILB7|uniprotkb:A8ILC1|uniprotkb:A8ILC8|uniprotkb:A8ILD1|uniprotkb:A8ILD6|uniprotkb:A8ILE1|uniprotkb:A8ILE5|ensemblmetazoa:FBpp0070794 psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:mof_drome(display_long)|uniprotkb:mof(gene name)|psi-mi:mof(display_short)|uniprotkb:Histone acetyl transferase MOF(gene name synonym)|uniprotkb:CG3025(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631967|imex:IM-22651-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000805"(X chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006281"(DNA repair)|go:"GO:0007549"(dosage compensation)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016456"(X chromosome located dosage compensation complex, transcription activating)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042393"(histone binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072487"(MSL complex)|go:"GO:2000873"(regulation of histone H4 acetylation involved in response to DNA damage stimulus)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037906|interpro:IPR040706|rcsb pdb:2BUD|ensemblmetazoa:FBgn0014340(gene)|ensemblmetazoa:FBtr0070829(transcript)|refseq:NP_511051.1|flybase:FBgn0014340|dip:DIP-46346N - - - figure legend:Fig. 3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 rogid:YoHi/N+rxfKrb2CV6iRu+e0BEvs7227 intact-crc:9277AC5AC89EC1F3|rigid:Cc+sNdAKXzE8ZnlwvUcjbCjRcsY false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VAF4 uniprotkb:Q9VZJ3 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 intact:EBI-168170|ensemblmetazoa:FBpp0073058 psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:q9vzj3_drome(display_long)|uniprotkb:Rcd5(gene name)|psi-mi:Rcd5(display_short)|uniprotkb:Dmel\CG1135(gene name synonym)|uniprotkb:MCRS1(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:dMCRS1(gene name synonym)|uniprotkb:dMCRS2(gene name synonym)|uniprotkb:"l(3)r0166"(gene name synonym)|uniprotkb:"l(3)rG166"(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:Dmel_CG1135(orf name)|uniprotkb:CG1135(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631967|imex:IM-22651-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 flybase:FBgn0263832|refseq:NP_647852.1|ensemblmetazoa:FBgn0263832(gene)|ensemblmetazoa:FBtr0073202(transcript)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0007099"(centriole replication)|go:"GO:0031011"(Ino80 complex)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|reactome:R-DME-5689603|reactome:R-DME-5696394 - - - figure legend:Fig. 3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 rogid:qPejBkSUFl+4R1spoQC8DELJm3o7227 intact-crc:9277AC5AC89EC1F3|rigid:Cc+sNdAKXzE8ZnlwvUcjbCjRcsY false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VAF4 uniprotkb:Q9VGA4 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 intact:EBI-134420|ensemblmetazoa:FBpp0082081 psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:q9vga4_drome(display_long)|uniprotkb:Dm Tam3(gene name synonym)|uniprotkb:Dmel\CG10042(gene name synonym)|uniprotkb:MBD(gene name synonym)|uniprotkb:MBDR2(gene name synonym)|uniprotkb:Mbdr2(gene name synonym)|uniprotkb:Mbrd2(gene name synonym)|uniprotkb:NSL(gene name synonym)|uniprotkb:TAM3(gene name synonym)|uniprotkb:dMBD-R2(gene name synonym)|uniprotkb:mbd-R2(gene name synonym)|uniprotkb:Dmel_CG10042(orf name)|uniprotkb:MBD-R2(gene name)|psi-mi:MBD-R2(display_short)|uniprotkb:CG17393(gene name synonym)|uniprotkb:CG10042(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631967|imex:IM-22651-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 refseq:NP_731688.2|flybase:FBgn0038016|ensemblmetazoa:FBgn0038016(gene)|ensemblmetazoa:FBtr0082611(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035327"|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR019786|interpro:IPR038441|interpro:IPR043449|reactome:R-DME-6804759 - - - figure legend:Fig. 3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 rogid:PSG4AsiVb879jORPcrjqUrGG3jg7227 intact-crc:9277AC5AC89EC1F3|rigid:Cc+sNdAKXzE8ZnlwvUcjbCjRcsY false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VAF4 uniprotkb:Q8T076 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 intact:EBI-3404081|ensemblmetazoa:FBpp0086709 psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:q8t076_drome(display_long)|uniprotkb:Dmel\CG8233(gene name synonym)|uniprotkb:NSL3(gene name synonym)|uniprotkb:Nsl3(gene name synonym)|uniprotkb:cg8233(gene name synonym)|uniprotkb:CG8233(orf name)|uniprotkb:Dmel_CG8233(orf name)|uniprotkb:Rcd1(gene name)|psi-mi:Rcd1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631967|imex:IM-22651-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 ensemblmetazoa:FBgn0033897(gene)|ensemblmetazoa:FBtr0087583(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007099"(centriole replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR026555|interpro:IPR029058|flybase:FBgn0033897|refseq:NP_610927.3 - - - figure legend:Fig. 3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 rogid:f1DkJOnV2ocyDS2fdoWT+G98fQc7227 intact-crc:9277AC5AC89EC1F3|rigid:Cc+sNdAKXzE8ZnlwvUcjbCjRcsY false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VAF4 uniprotkb:A4V2Z1 intact:EBI-120581|uniprotkb:Q95RT2|ensemblmetazoa:FBpp0084893 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 psi-mi:q9vaf4_drome(display_long)|uniprotkb:dgt1(gene name)|psi-mi:dgt1(display_short)|uniprotkb:Dgt1(gene name synonym)|uniprotkb:Dmel\CG18041(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym)|uniprotkb:CG18041(orf name)|uniprotkb:Dmel_CG18041(orf name) psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9631967|imex:IM-22651-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0039710(gene)|ensemblmetazoa:FBtr0085527(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|rcsb pdb:4CY5|refseq:NP_651737.1|flybase:FBgn0039710 refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - figure legend:Fig. 3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-sl2)|taxid:7227(Drosophila melanogaster sl1 cells) - 2014/06/18 2014/10/16 rogid:6xMzXnYUTyG4+OZFeSbHUabip3Q7227 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 intact-crc:9277AC5AC89EC1F3|rigid:Cc+sNdAKXzE8ZnlwvUcjbCjRcsY false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A4V2Z1 intact:EBI-9632058 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 flybase:FBgn0266670 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:sec5_drome_gene(display_short)|psi-mi:EBI-9632058(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632083|imex:IM-22651-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - - figure legend:Suppl. Fig. S7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 - intact-crc:971373A34FA2714D false mutation decreasing interaction:721-721|flag tag:?-? binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:A4V2Z1 intact:EBI-9632058 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 flybase:FBgn0266670 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:sec5_drome_gene(display_short)|psi-mi:EBI-9632058(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632077|imex:IM-22651-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - - figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 - intact-crc:F53549C13E561F0C false mutation decreasing interaction:721-721 binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) intact:EBI-9632060 uniprotkb:A4V2Z1 flybase:FBgn0035518 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 psi-mi:cg15011_drome_gene(display_short)|psi-mi:EBI-9632060(display_long) psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632100|imex:IM-22651-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - figure legend:Suppl. Fig. S7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 - rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 intact-crc:728D86A9D2DD23F7 false binding-associated region:?-? flag tag:?-?|mutation decreasing interaction:721-721 - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:A4V2Z1 intact:EBI-9632060 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 flybase:FBgn0035518 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:cg15011_drome_gene(display_short)|psi-mi:EBI-9632060(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632091|imex:IM-22651-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - - figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 - intact-crc:1A35CC11D11A627F false mutation decreasing interaction:721-721 binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:A4V2Z1 intact:EBI-9632062 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 flybase:FBgn0067864 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:patj_drome_gene(display_short)|psi-mi:EBI-9632062(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632116|imex:IM-22651-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - - figure legend:Suppl. Fig. S7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 - intact-crc:B5C80748A3868526 false mutation decreasing interaction:721-721|flag tag:?-? binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) intact:EBI-9632062 uniprotkb:A4V2Z1 flybase:FBgn0067864 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 psi-mi:patj_drome_gene(display_short)|psi-mi:EBI-9632062(display_long) psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632109|imex:IM-22651-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 - rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 intact-crc:6D5DF54081A12B0B false binding-associated region:?-? mutation decreasing interaction:721-721 - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) intact:EBI-9632064 uniprotkb:A4V2Z1 flybase:FBgn0031390 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 psi-mi:tho2_drome_gene(display_short)|psi-mi:EBI-9632064(display_long) psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632125|imex:IM-22651-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 - rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 intact-crc:CC2202F3252AFF2D false binding-associated region:?-? mutation decreasing interaction:721-721 - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:A4V2Z1 intact:EBI-9632064 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 flybase:FBgn0031390 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:tho2_drome_gene(display_short)|psi-mi:EBI-9632064(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632132|imex:IM-22651-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - - figure legend:Suppl. Fig. S7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 - intact-crc:5F6B99178753E2C9 false mutation decreasing interaction:721-721|flag tag:?-? binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) intact:EBI-9632066 uniprotkb:A4V2Z1 flybase:FBgn0030874 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 psi-mi:cg6506_drome_gene(display_short)|psi-mi:EBI-9632066(display_long) psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632148|imex:IM-22651-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - figure legend:Suppl. Fig. S7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 - rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 intact-crc:04E754B29EAEF352 false binding-associated region:?-? mutation decreasing interaction:721-721|flag tag:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:A4V2Z1 intact:EBI-9632066 intact:EBI-9630827|ensemblmetazoa:FBpp0290940|ensemblmetazoa:FBpp0290944|ensemblmetazoa:FBpp0290945 flybase:FBgn0030874 psi-mi:a4v2z1_drome(display_long)|uniprotkb:nsl1(gene name)|psi-mi:nsl1(display_short)|uniprotkb:wah(gene name synonym)|uniprotkb:Dmel_CG4699(orf name)|uniprotkb:Dmel\CG4699(gene name synonym)|uniprotkb:"E(nos)"(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Nsl1(gene name synonym)|uniprotkb:"l(3)06536"(gene name synonym)|uniprotkb:"l(3)S009413"(gene name synonym)|uniprotkb:CG4699(orf name) psi-mi:cg6506_drome_gene(display_short)|psi-mi:EBI-9632066(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632141|imex:IM-22651-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001163621.1|refseq:NP_001163623.1|refseq:NP_732070.2|flybase:FBgn0262527|ensemblmetazoa:FBgn0262527(gene)|ensemblmetazoa:FBtr0301726(transcript)|ensemblmetazoa:FBtr0301731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044545"(NSL complex)|go:"GO:0048477"(oogenesis)|interpro:IPR026180|interpro:IPR029332|rcsb pdb:4CY3|rcsb pdb:4CY5|ensemblmetazoa:FBtr0301730(transcript) - - - - figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 rogid:uy5WR0qYkOj7rWrkHGxYL7pxDIA7227 - intact-crc:8BB6CF8F914DF0EB false mutation decreasing interaction:721-721 binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) intact:EBI-9632058 uniprotkb:Q9VGA4 flybase:FBgn0266670 intact:EBI-134420|ensemblmetazoa:FBpp0082081 psi-mi:sec5_drome_gene(display_short)|psi-mi:EBI-9632058(display_long) psi-mi:q9vga4_drome(display_long)|uniprotkb:Dm Tam3(gene name synonym)|uniprotkb:Dmel\CG10042(gene name synonym)|uniprotkb:MBD(gene name synonym)|uniprotkb:MBDR2(gene name synonym)|uniprotkb:Mbdr2(gene name synonym)|uniprotkb:Mbrd2(gene name synonym)|uniprotkb:NSL(gene name synonym)|uniprotkb:TAM3(gene name synonym)|uniprotkb:dMBD-R2(gene name synonym)|uniprotkb:mbd-R2(gene name synonym)|uniprotkb:Dmel_CG10042(orf name)|uniprotkb:MBD-R2(gene name)|psi-mi:MBD-R2(display_short)|uniprotkb:CG17393(gene name synonym)|uniprotkb:CG10042(orf name) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632157|imex:IM-22651-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_731688.2|flybase:FBgn0038016|ensemblmetazoa:FBgn0038016(gene)|ensemblmetazoa:FBtr0082611(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035327"|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR019786|interpro:IPR038441|interpro:IPR043449|reactome:R-DME-6804759 - - - figure legend:Fig. 4c|comment:MBD-R2 ChIP recovery was reduced in Drosophila larvae containing the arg721ala NSL1 mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 - rogid:PSG4AsiVb879jORPcrjqUrGG3jg7227 intact-crc:4DC3D1DFC401A7BB false binding-associated region:?-? - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) intact:EBI-9632060 uniprotkb:Q9VGA4 flybase:FBgn0035518 intact:EBI-134420|ensemblmetazoa:FBpp0082081 psi-mi:cg15011_drome_gene(display_short)|psi-mi:EBI-9632060(display_long) psi-mi:q9vga4_drome(display_long)|uniprotkb:Dm Tam3(gene name synonym)|uniprotkb:Dmel\CG10042(gene name synonym)|uniprotkb:MBD(gene name synonym)|uniprotkb:MBDR2(gene name synonym)|uniprotkb:Mbdr2(gene name synonym)|uniprotkb:Mbrd2(gene name synonym)|uniprotkb:NSL(gene name synonym)|uniprotkb:TAM3(gene name synonym)|uniprotkb:dMBD-R2(gene name synonym)|uniprotkb:mbd-R2(gene name synonym)|uniprotkb:Dmel_CG10042(orf name)|uniprotkb:MBD-R2(gene name)|psi-mi:MBD-R2(display_short)|uniprotkb:CG17393(gene name synonym)|uniprotkb:CG10042(orf name) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632165|imex:IM-22651-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_731688.2|flybase:FBgn0038016|ensemblmetazoa:FBgn0038016(gene)|ensemblmetazoa:FBtr0082611(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035327"|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR019786|interpro:IPR038441|interpro:IPR043449|reactome:R-DME-6804759 - - - figure legend:Fig. 4c|comment:MBD-R2 ChIP recovery was reduced in Drosophila larvae containing the arg721ala NSL1 mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 - rogid:PSG4AsiVb879jORPcrjqUrGG3jg7227 intact-crc:122426E2C8A0FB84 false binding-associated region:?-? - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:Q9VGA4 intact:EBI-9632062 intact:EBI-134420|ensemblmetazoa:FBpp0082081 flybase:FBgn0067864 psi-mi:q9vga4_drome(display_long)|uniprotkb:Dm Tam3(gene name synonym)|uniprotkb:Dmel\CG10042(gene name synonym)|uniprotkb:MBD(gene name synonym)|uniprotkb:MBDR2(gene name synonym)|uniprotkb:Mbdr2(gene name synonym)|uniprotkb:Mbrd2(gene name synonym)|uniprotkb:NSL(gene name synonym)|uniprotkb:TAM3(gene name synonym)|uniprotkb:dMBD-R2(gene name synonym)|uniprotkb:mbd-R2(gene name synonym)|uniprotkb:Dmel_CG10042(orf name)|uniprotkb:MBD-R2(gene name)|psi-mi:MBD-R2(display_short)|uniprotkb:CG17393(gene name synonym)|uniprotkb:CG10042(orf name) psi-mi:patj_drome_gene(display_short)|psi-mi:EBI-9632062(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632173|imex:IM-22651-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_731688.2|flybase:FBgn0038016|ensemblmetazoa:FBgn0038016(gene)|ensemblmetazoa:FBtr0082611(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035327"|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR019786|interpro:IPR038441|interpro:IPR043449|reactome:R-DME-6804759 - - - - figure legend:Fig. 4c|comment:MBD-R2 ChIP recovery was reduced in Drosophila larvae containing the arg721ala NSL1 mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 rogid:PSG4AsiVb879jORPcrjqUrGG3jg7227 - intact-crc:FAA1B8864A7AC624 false - binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:Q9VGA4 intact:EBI-9632064 intact:EBI-134420|ensemblmetazoa:FBpp0082081 flybase:FBgn0031390 psi-mi:q9vga4_drome(display_long)|uniprotkb:Dm Tam3(gene name synonym)|uniprotkb:Dmel\CG10042(gene name synonym)|uniprotkb:MBD(gene name synonym)|uniprotkb:MBDR2(gene name synonym)|uniprotkb:Mbdr2(gene name synonym)|uniprotkb:Mbrd2(gene name synonym)|uniprotkb:NSL(gene name synonym)|uniprotkb:TAM3(gene name synonym)|uniprotkb:dMBD-R2(gene name synonym)|uniprotkb:mbd-R2(gene name synonym)|uniprotkb:Dmel_CG10042(orf name)|uniprotkb:MBD-R2(gene name)|psi-mi:MBD-R2(display_short)|uniprotkb:CG17393(gene name synonym)|uniprotkb:CG10042(orf name) psi-mi:tho2_drome_gene(display_short)|psi-mi:EBI-9632064(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632191|imex:IM-22651-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_731688.2|flybase:FBgn0038016|ensemblmetazoa:FBgn0038016(gene)|ensemblmetazoa:FBtr0082611(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035327"|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR019786|interpro:IPR038441|interpro:IPR043449|reactome:R-DME-6804759 - - - - figure legend:Fig. 4c|comment:MBD-R2 ChIP recovery was reduced in Drosophila larvae containing the arg721ala NSL1 mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 rogid:PSG4AsiVb879jORPcrjqUrGG3jg7227 - intact-crc:F99D2A59DE519490 false - binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) intact:EBI-9632066 uniprotkb:Q9VGA4 flybase:FBgn0030874 intact:EBI-134420|ensemblmetazoa:FBpp0082081 psi-mi:cg6506_drome_gene(display_short)|psi-mi:EBI-9632066(display_long) psi-mi:q9vga4_drome(display_long)|uniprotkb:Dm Tam3(gene name synonym)|uniprotkb:Dmel\CG10042(gene name synonym)|uniprotkb:MBD(gene name synonym)|uniprotkb:MBDR2(gene name synonym)|uniprotkb:Mbdr2(gene name synonym)|uniprotkb:Mbrd2(gene name synonym)|uniprotkb:NSL(gene name synonym)|uniprotkb:TAM3(gene name synonym)|uniprotkb:dMBD-R2(gene name synonym)|uniprotkb:mbd-R2(gene name synonym)|uniprotkb:Dmel_CG10042(orf name)|uniprotkb:MBD-R2(gene name)|psi-mi:MBD-R2(display_short)|uniprotkb:CG17393(gene name synonym)|uniprotkb:CG10042(orf name) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632199|imex:IM-22651-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_731688.2|flybase:FBgn0038016|ensemblmetazoa:FBgn0038016(gene)|ensemblmetazoa:FBtr0082611(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035327"|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR019786|interpro:IPR038441|interpro:IPR043449|reactome:R-DME-6804759 - - - figure legend:Fig. 4c|comment:MBD-R2 ChIP recovery was reduced in Drosophila larvae containing the arg721ala NSL1 mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2014/06/18 2014/10/16 - rogid:PSG4AsiVb879jORPcrjqUrGG3jg7227 intact-crc:DE51F9FD9B45C5D4 false binding-associated region:?-? - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:Q7Z3B3 uniprotkb:P61964 intact:EBI-740244|uniprotkb:Q6AW85|uniprotkb:Q8IYH1|uniprotkb:Q9BRH0|uniprotkb:Q9NTE7|uniprotkb:Q9UFT0|uniprotkb:Q9ULF3|uniprotkb:A8K5E4|ensembl:ENSP00000262419|ensembl:ENSP00000387393|ensembl:ENSP00000461484|ensembl:ENSP00000461812|intact:EBI-10178305|uniprotkb:B3KT49|uniprotkb:I3L4J3 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:kanl1_human(display_long)|uniprotkb:KANSL1(gene name)|psi-mi:KANSL1(display_short)|uniprotkb:KIAA1267(gene name synonym)|uniprotkb:MLL1/MLL complex subunit KANSL1(gene name synonym)|uniprotkb:MSL1 homolog 1(gene name synonym)|uniprotkb:MSL1V1(gene name synonym)|uniprotkb:NSL complex protein NSL1(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Non-specific lethal 1 homolog(gene name synonym)|uniprotkb:CENP-36(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632363|imex:IM-22651-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180394.1|refseq:NP_001180395.1|refseq:NP_056258.1|refseq:XP_006721886.1|ensembl:ENSG00000120071(gene)|ensembl:ENST00000262419(transcript)|ensembl:ENST00000432791(transcript)|ensembl:ENST00000572904(transcript)|ensembl:ENST00000574590(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR026180|interpro:IPR029332|mint:Q7Z3B3|rcsb pdb:4CY1|rcsb pdb:4CY2|reactome:R-HSA-3214847|refseq:XP_006721887.1 refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - - figure legend:Suppl. Fig. S2b, Suppl. Fig. S2c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:Co/MKm4PZcwn3BUf6ZKYOqW0VhA9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:290EA3B59669584A|rigid:95MS4kir7YECtzi8jCf3QxTeiLI false sufficient binding region:537-773 sufficient binding region:23-334(IPR001680) - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P61964 uniprotkb:Q9H9L4 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2560840|uniprotkb:Q8N3B5|uniprotkb:Q9NX51|uniprotkb:Q96CV0|ensembl:ENSP00000415436 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kanl2_human(display_long)|uniprotkb:KANSL2(gene name)|psi-mi:KANSL2(display_short)|uniprotkb:C12orf41(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Dias et al. (2014) imex:IM-22651|pubmed:24788516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9632375|imex:IM-22651-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_060292.3|ensembl:ENSG00000139620(gene)|ensembl:ENST00000420613(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|mint:Q9H9L4|rcsb pdb:4CY2|reactome:R-HSA-3214847 - - - figure legend:Suppl. Fig. S4, Suppl. Fig. S5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/18 2014/10/16 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:ymOXqnaeH6HuGcHPg4R2XVmWAz89606 intact-crc:FF73DDD5B215B6A0|rigid:zY171Pab7wK7Zm2B7QpdUdVvmTI false sufficient binding region:23-334(IPR001680) sufficient binding region:381-492|mutation disrupting interaction:413-413 - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining)