#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q14674	uniprotkb:O95997	intact:EBI-2554882|intact:EBI-28978215|ensembl:ENSP00000257934	intact:EBI-2551072|ensembl:ENSP00000344936|ensembl:ENSP00000377536|ensembl:ENSP00000430642	psi-mi:espl1_human(display_long)|uniprotkb:ESP1(gene name synonym)|uniprotkb:KIAA0165(gene name synonym)|uniprotkb:Separase(gene name synonym)|uniprotkb:Caspase-like protein ESPL1(gene name synonym)|uniprotkb:Extra spindle poles-like 1 protein(gene name synonym)|uniprotkb:ESPL1(gene name)|psi-mi:ESPL1(display_short)	psi-mi:pttg1_human(display_long)|uniprotkb:EAP1(gene name synonym)|uniprotkb:PTTG(gene name synonym)|uniprotkb:TUTR1(gene name synonym)|uniprotkb:Pituitary tumor-transforming gene 1 protein(gene name synonym)|uniprotkb:Esp1-associated protein(gene name synonym)|uniprotkb:PTTG1(gene name)|psi-mi:PTTG1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hellmuth et al. (2014)	pubmed:24781523|imex:IM-23411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9828000|imex:IM-23411-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036423.4|refseq:XP_011537326.1|ensembl:ENSP00000257934|refseq:XP_006719768.1|refseq:XP_016875742.1|dip:DIP-46079N|ensembl:ENST00000257934(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003824"(catalytic activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|reactome:R-HSA-2467813|ensembl:ENSG00000135476(gene)	ensembl:ENSG00000164611(gene)|ensembl:ENST00000352433(transcript)|ensembl:ENST00000393964(transcript)|ensembl:ENST00000520452(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007283"(spermatogenesis)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:2000816"(negative regulation of mitotic sister chromatid separation)|interpro:IPR006940(Securin sister-chromatid separation inhibitor)|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-2467813|refseq:NP_004210.1|refseq:NP_001269311.1|refseq:NP_001269312.1|dip:DIP-56460N	-	-	-	figure legend:sf1a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/02	2014/10/16	rogid:oK4Wg46DenILU6xADFkxkybkOcI9606	rogid:CsVFdecK6rCfJkLuzlnvom1nsB89606	intact-crc:DD553CB4BD8B3B4C|rigid:d5Su/MGpaPVsK4AYWuGHI08gDfc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14674	uniprotkb:O95997	intact:EBI-2554882|intact:EBI-28978215|ensembl:ENSP00000257934	intact:EBI-2551072|ensembl:ENSP00000344936|ensembl:ENSP00000377536|ensembl:ENSP00000430642	psi-mi:espl1_human(display_long)|uniprotkb:ESP1(gene name synonym)|uniprotkb:KIAA0165(gene name synonym)|uniprotkb:Separase(gene name synonym)|uniprotkb:Caspase-like protein ESPL1(gene name synonym)|uniprotkb:Extra spindle poles-like 1 protein(gene name synonym)|uniprotkb:ESPL1(gene name)|psi-mi:ESPL1(display_short)	psi-mi:pttg1_human(display_long)|uniprotkb:EAP1(gene name synonym)|uniprotkb:PTTG(gene name synonym)|uniprotkb:TUTR1(gene name synonym)|uniprotkb:Pituitary tumor-transforming gene 1 protein(gene name synonym)|uniprotkb:Esp1-associated protein(gene name synonym)|uniprotkb:PTTG1(gene name)|psi-mi:PTTG1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hellmuth et al. (2014)	pubmed:24781523|imex:IM-23411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9828000|imex:IM-23411-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036423.4|refseq:XP_011537326.1|ensembl:ENSP00000257934|refseq:XP_006719768.1|refseq:XP_016875742.1|dip:DIP-46079N|ensembl:ENST00000257934(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003824"(catalytic activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|reactome:R-HSA-2467813|ensembl:ENSG00000135476(gene)	ensembl:ENSG00000164611(gene)|ensembl:ENST00000352433(transcript)|ensembl:ENST00000393964(transcript)|ensembl:ENST00000520452(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007283"(spermatogenesis)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:2000816"(negative regulation of mitotic sister chromatid separation)|interpro:IPR006940(Securin sister-chromatid separation inhibitor)|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-2467813|refseq:NP_004210.1|refseq:NP_001269311.1|refseq:NP_001269312.1|dip:DIP-56460N	-	-	-	figure legend:sf1a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/02	2014/10/16	rogid:oK4Wg46DenILU6xADFkxkybkOcI9606	rogid:CsVFdecK6rCfJkLuzlnvom1nsB89606	intact-crc:DD553CB4BD8B3B4C|rigid:d5Su/MGpaPVsK4AYWuGHI08gDfc	false	-	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14674	uniprotkb:O95997	intact:EBI-2554882|intact:EBI-28978215|ensembl:ENSP00000257934	intact:EBI-2551072|ensembl:ENSP00000344936|ensembl:ENSP00000377536|ensembl:ENSP00000430642	psi-mi:espl1_human(display_long)|uniprotkb:ESP1(gene name synonym)|uniprotkb:KIAA0165(gene name synonym)|uniprotkb:Separase(gene name synonym)|uniprotkb:Caspase-like protein ESPL1(gene name synonym)|uniprotkb:Extra spindle poles-like 1 protein(gene name synonym)|uniprotkb:ESPL1(gene name)|psi-mi:ESPL1(display_short)	psi-mi:pttg1_human(display_long)|uniprotkb:EAP1(gene name synonym)|uniprotkb:PTTG(gene name synonym)|uniprotkb:TUTR1(gene name synonym)|uniprotkb:Pituitary tumor-transforming gene 1 protein(gene name synonym)|uniprotkb:Esp1-associated protein(gene name synonym)|uniprotkb:PTTG1(gene name)|psi-mi:PTTG1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hellmuth et al. (2014)	pubmed:24781523|imex:IM-23411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9827725|imex:IM-23411-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036423.4|refseq:XP_011537326.1|ensembl:ENSP00000257934|refseq:XP_006719768.1|refseq:XP_016875742.1|dip:DIP-46079N|ensembl:ENST00000257934(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003824"(catalytic activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|reactome:R-HSA-2467813|ensembl:ENSG00000135476(gene)	ensembl:ENSG00000164611(gene)|ensembl:ENST00000352433(transcript)|ensembl:ENST00000393964(transcript)|ensembl:ENST00000520452(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007283"(spermatogenesis)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:2000816"(negative regulation of mitotic sister chromatid separation)|interpro:IPR006940(Securin sister-chromatid separation inhibitor)|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-2467813|refseq:NP_004210.1|refseq:NP_001269311.1|refseq:NP_001269312.1|dip:DIP-56460N	-	-	-	figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/02	2014/10/16	rogid:oK4Wg46DenILU6xADFkxkybkOcI9606	rogid:CsVFdecK6rCfJkLuzlnvom1nsB89606	intact-crc:526C642211FDD8EF|rigid:qevuk8mR8q47M9xxgpbZB17U+QY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14674	uniprotkb:P67775	intact:EBI-2554882|intact:EBI-28978215|ensembl:ENSP00000257934	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:espl1_human(display_long)|uniprotkb:ESP1(gene name synonym)|uniprotkb:KIAA0165(gene name synonym)|uniprotkb:Separase(gene name synonym)|uniprotkb:Caspase-like protein ESPL1(gene name synonym)|uniprotkb:Extra spindle poles-like 1 protein(gene name synonym)|uniprotkb:ESPL1(gene name)|psi-mi:ESPL1(display_short)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hellmuth et al. (2014)	pubmed:24781523|imex:IM-23411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9827725|imex:IM-23411-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036423.4|refseq:XP_011537326.1|ensembl:ENSP00000257934|refseq:XP_006719768.1|refseq:XP_016875742.1|dip:DIP-46079N|ensembl:ENST00000257934(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003824"(catalytic activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|reactome:R-HSA-2467813|ensembl:ENSG00000135476(gene)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	-	-	-	figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/02	2014/10/16	rogid:oK4Wg46DenILU6xADFkxkybkOcI9606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	intact-crc:526C642211FDD8EF|rigid:qevuk8mR8q47M9xxgpbZB17U+QY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14674	uniprotkb:P14635	intact:EBI-2554882|intact:EBI-28978215|ensembl:ENSP00000257934	intact:EBI-495332|uniprotkb:A8K066|uniprotkb:Q5TZP9|ensembl:ENSP00000256442	psi-mi:espl1_human(display_long)|uniprotkb:ESP1(gene name synonym)|uniprotkb:KIAA0165(gene name synonym)|uniprotkb:Separase(gene name synonym)|uniprotkb:Caspase-like protein ESPL1(gene name synonym)|uniprotkb:Extra spindle poles-like 1 protein(gene name synonym)|uniprotkb:ESPL1(gene name)|psi-mi:ESPL1(display_short)	psi-mi:ccnb1_human(display_long)|uniprotkb:CCNB1(gene name)|psi-mi:CCNB1(display_short)|uniprotkb:CCNB(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hellmuth et al. (2014)	pubmed:24781523|imex:IM-23411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9827936|imex:IM-23411-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036423.4|refseq:XP_011537326.1|ensembl:ENSP00000257934|refseq:XP_006719768.1|refseq:XP_016875742.1|dip:DIP-46079N|ensembl:ENST00000257934(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003824"(catalytic activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|reactome:R-HSA-2467813|ensembl:ENSG00000135476(gene)	refseq:NP_114172.1|dip:DIP-59N|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042493"|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046680"(response to DDT)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048565"(digestive tract development)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|ensembl:ENSG00000134057(gene)|ensembl:ENST00000256442(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005113"(patched binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|go:"GO:2000775"(obsolete histone H3-S10 phosphorylation involved in chromosome condensation)|interpro:IPR004367(Cyclin, C-terminal)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071283"("cellular response to iron(III) ion")|interpro:IPR039361|mint:P14635|rcsb pdb:2B9R|rcsb pdb:2JGZ|rcsb pdb:4Y72|rcsb pdb:4YC3|go:"GO:0071398"(cellular response to fatty acid)|rcsb pdb:5HQ0|go:"GO:0071407"(cellular response to organic cyclic compound)|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|reactome:R-HSA-113507|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174048|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|go:"GO:0071456"(cellular response to hypoxia)|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-4419969|reactome:R-HSA-6804114|reactome:R-HSA-68875|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8878166|reactome:R-HSA-8852276	-	-	-	figure legend:f1e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/02	2014/10/16	rogid:oK4Wg46DenILU6xADFkxkybkOcI9606	rogid:WCQWqI2kWZfatq4L2DC0hm26Ix09606	intact-crc:526AA42211FDD8EF|rigid:LkN0b2w9xC3jplz4hMCtNWTMgHw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14674	uniprotkb:O95997	intact:EBI-2554882|intact:EBI-28978215|ensembl:ENSP00000257934	intact:EBI-2551072|ensembl:ENSP00000344936|ensembl:ENSP00000377536|ensembl:ENSP00000430642	psi-mi:espl1_human(display_long)|uniprotkb:ESP1(gene name synonym)|uniprotkb:KIAA0165(gene name synonym)|uniprotkb:Separase(gene name synonym)|uniprotkb:Caspase-like protein ESPL1(gene name synonym)|uniprotkb:Extra spindle poles-like 1 protein(gene name synonym)|uniprotkb:ESPL1(gene name)|psi-mi:ESPL1(display_short)	psi-mi:pttg1_human(display_long)|uniprotkb:EAP1(gene name synonym)|uniprotkb:PTTG(gene name synonym)|uniprotkb:TUTR1(gene name synonym)|uniprotkb:Pituitary tumor-transforming gene 1 protein(gene name synonym)|uniprotkb:Esp1-associated protein(gene name synonym)|uniprotkb:PTTG1(gene name)|psi-mi:PTTG1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hellmuth et al. (2014)	pubmed:24781523|imex:IM-23411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9827936|imex:IM-23411-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036423.4|refseq:XP_011537326.1|ensembl:ENSP00000257934|refseq:XP_006719768.1|refseq:XP_016875742.1|dip:DIP-46079N|ensembl:ENST00000257934(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003824"(catalytic activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|reactome:R-HSA-2467813|ensembl:ENSG00000135476(gene)	ensembl:ENSG00000164611(gene)|ensembl:ENST00000352433(transcript)|ensembl:ENST00000393964(transcript)|ensembl:ENST00000520452(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007283"(spermatogenesis)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:2000816"(negative regulation of mitotic sister chromatid separation)|interpro:IPR006940(Securin sister-chromatid separation inhibitor)|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-2467813|refseq:NP_004210.1|refseq:NP_001269311.1|refseq:NP_001269312.1|dip:DIP-56460N	-	-	-	figure legend:f1e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/02	2014/10/16	rogid:oK4Wg46DenILU6xADFkxkybkOcI9606	rogid:CsVFdecK6rCfJkLuzlnvom1nsB89606	intact-crc:526AA42211FDD8EF|rigid:LkN0b2w9xC3jplz4hMCtNWTMgHw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P30260	uniprotkb:Q12834	intact:EBI-994813|uniprotkb:Q16349|uniprotkb:Q96F35|ensembl:ENSP00000066544|uniprotkb:G3V1C4|intact:EBI-10972530	intact:EBI-367462|uniprotkb:Q5JUY4|uniprotkb:Q9BW56|uniprotkb:Q9UQI9|uniprotkb:B2R6Z6|uniprotkb:D3DPJ1|ensembl:ENSP00000308450|ensembl:ENSP00000361540	psi-mi:cdc27_human(display_long)|uniprotkb:CDC27(gene name)|psi-mi:CDC27(display_short)|uniprotkb:D0S1430E(gene name synonym)|uniprotkb:D17S978E(gene name synonym)|uniprotkb:CDC27 homolog(gene name synonym)|uniprotkb:H-NUC(gene name synonym)|uniprotkb:ANAPC3(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 3(gene name synonym)	psi-mi:cdc20_human(display_long)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:p55CDC(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hellmuth et al. (2014)	pubmed:24781523|imex:IM-23411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9827995|imex:IM-23411-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000004897(gene)|ensembl:ENST00000066544(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0072686"(mitotic spindle)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:3T1N|go:"GO:0005680"(anaphase-promoting complex)|rcsb pdb:4RG6|rcsb pdb:4RG7|rcsb pdb:4RG9|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:NP_001107563.1|refseq:NP_001247.3|dip:DIP-36422N	rcsb pdb:6Q6H|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174048|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176417|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-5689880|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983168|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051301"(cell division)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q12834|rcsb pdb:4GGA|rcsb pdb:4GGC|rcsb pdb:4GGD|rcsb pdb:4N14|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6Q6G|refseq:NP_001246.2|ensembl:ENSG00000117399(gene)|ensembl:ENST00000310955(transcript)|ensembl:ENST00000372462(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-29655N	-	-	-	figure legend:f3e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/02	2015/08/14	rogid:YOrJCRal5ZfO7kP2b8FPon0Yytw9606	rogid:15j9Heovw6LpbClp5kT9Wz6a88A9606	intact-crc:E0A7BB7885892543|rigid:a1Wo6oPrJ0BDF3U+v/I/vz4S9Wg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14674	uniprotkb:P14635	intact:EBI-2554882|intact:EBI-28978215|ensembl:ENSP00000257934	intact:EBI-495332|uniprotkb:A8K066|uniprotkb:Q5TZP9|ensembl:ENSP00000256442	psi-mi:espl1_human(display_long)|uniprotkb:ESP1(gene name synonym)|uniprotkb:KIAA0165(gene name synonym)|uniprotkb:Separase(gene name synonym)|uniprotkb:Caspase-like protein ESPL1(gene name synonym)|uniprotkb:Extra spindle poles-like 1 protein(gene name synonym)|uniprotkb:ESPL1(gene name)|psi-mi:ESPL1(display_short)	psi-mi:ccnb1_human(display_long)|uniprotkb:CCNB1(gene name)|psi-mi:CCNB1(display_short)|uniprotkb:CCNB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hellmuth et al. (2014)	pubmed:24781523|imex:IM-23411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9828019|imex:IM-23411-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036423.4|refseq:XP_011537326.1|ensembl:ENSP00000257934|refseq:XP_006719768.1|refseq:XP_016875742.1|dip:DIP-46079N|ensembl:ENST00000257934(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003824"(catalytic activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|reactome:R-HSA-2467813|ensembl:ENSG00000135476(gene)	refseq:NP_114172.1|dip:DIP-59N|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042493"|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046680"(response to DDT)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048565"(digestive tract development)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|ensembl:ENSG00000134057(gene)|ensembl:ENST00000256442(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005113"(patched binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|go:"GO:2000775"(obsolete histone H3-S10 phosphorylation involved in chromosome condensation)|interpro:IPR004367(Cyclin, C-terminal)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071283"("cellular response to iron(III) ion")|interpro:IPR039361|mint:P14635|rcsb pdb:2B9R|rcsb pdb:2JGZ|rcsb pdb:4Y72|rcsb pdb:4YC3|go:"GO:0071398"(cellular response to fatty acid)|rcsb pdb:5HQ0|go:"GO:0071407"(cellular response to organic cyclic compound)|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|reactome:R-HSA-113507|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174048|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|go:"GO:0071456"(cellular response to hypoxia)|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-4419969|reactome:R-HSA-6804114|reactome:R-HSA-68875|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8878166|reactome:R-HSA-8852276	-	-	-	figure legend:sf8a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/02	2014/12/02	rogid:oK4Wg46DenILU6xADFkxkybkOcI9606	rogid:WCQWqI2kWZfatq4L2DC0hm26Ix09606	intact-crc:9101FF6A2A4DE512|rigid:ba7tSaAX6JOoWb/gIYyqg7RWX1Q	false	myc tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14674	uniprotkb:P67775	intact:EBI-2554882|intact:EBI-28978215|ensembl:ENSP00000257934	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:espl1_human(display_long)|uniprotkb:ESP1(gene name synonym)|uniprotkb:KIAA0165(gene name synonym)|uniprotkb:Separase(gene name synonym)|uniprotkb:Caspase-like protein ESPL1(gene name synonym)|uniprotkb:Extra spindle poles-like 1 protein(gene name synonym)|uniprotkb:ESPL1(gene name)|psi-mi:ESPL1(display_short)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hellmuth et al. (2014)	pubmed:24781523|imex:IM-23411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9828019|imex:IM-23411-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036423.4|refseq:XP_011537326.1|ensembl:ENSP00000257934|refseq:XP_006719768.1|refseq:XP_016875742.1|dip:DIP-46079N|ensembl:ENST00000257934(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003824"(catalytic activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|reactome:R-HSA-2467813|ensembl:ENSG00000135476(gene)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	-	-	-	figure legend:sf8a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/02	2014/12/02	rogid:oK4Wg46DenILU6xADFkxkybkOcI9606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	intact-crc:9101FF6A2A4DE512|rigid:ba7tSaAX6JOoWb/gIYyqg7RWX1Q	false	myc tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14674	uniprotkb:O95997	intact:EBI-2554882|intact:EBI-28978215|ensembl:ENSP00000257934	intact:EBI-2551072|ensembl:ENSP00000344936|ensembl:ENSP00000377536|ensembl:ENSP00000430642	psi-mi:espl1_human(display_long)|uniprotkb:ESP1(gene name synonym)|uniprotkb:KIAA0165(gene name synonym)|uniprotkb:Separase(gene name synonym)|uniprotkb:Caspase-like protein ESPL1(gene name synonym)|uniprotkb:Extra spindle poles-like 1 protein(gene name synonym)|uniprotkb:ESPL1(gene name)|psi-mi:ESPL1(display_short)	psi-mi:pttg1_human(display_long)|uniprotkb:EAP1(gene name synonym)|uniprotkb:PTTG(gene name synonym)|uniprotkb:TUTR1(gene name synonym)|uniprotkb:Pituitary tumor-transforming gene 1 protein(gene name synonym)|uniprotkb:Esp1-associated protein(gene name synonym)|uniprotkb:PTTG1(gene name)|psi-mi:PTTG1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hellmuth et al. (2014)	pubmed:24781523|imex:IM-23411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9828019|imex:IM-23411-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036423.4|refseq:XP_011537326.1|ensembl:ENSP00000257934|refseq:XP_006719768.1|refseq:XP_016875742.1|dip:DIP-46079N|ensembl:ENST00000257934(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003824"(catalytic activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|reactome:R-HSA-2467813|ensembl:ENSG00000135476(gene)	ensembl:ENSG00000164611(gene)|ensembl:ENST00000352433(transcript)|ensembl:ENST00000393964(transcript)|ensembl:ENST00000520452(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007283"(spermatogenesis)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:2000816"(negative regulation of mitotic sister chromatid separation)|interpro:IPR006940(Securin sister-chromatid separation inhibitor)|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-2467813|refseq:NP_004210.1|refseq:NP_001269311.1|refseq:NP_001269312.1|dip:DIP-56460N	-	-	-	figure legend:sf8a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/02	2014/12/02	rogid:oK4Wg46DenILU6xADFkxkybkOcI9606	rogid:CsVFdecK6rCfJkLuzlnvom1nsB89606	intact-crc:9101FF6A2A4DE512|rigid:ba7tSaAX6JOoWb/gIYyqg7RWX1Q	false	myc tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14674	uniprotkb:P30154	intact:EBI-2554882|intact:EBI-28978215|ensembl:ENSP00000257934	intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193	psi-mi:espl1_human(display_long)|uniprotkb:ESP1(gene name synonym)|uniprotkb:KIAA0165(gene name synonym)|uniprotkb:Separase(gene name synonym)|uniprotkb:Caspase-like protein ESPL1(gene name synonym)|uniprotkb:Extra spindle poles-like 1 protein(gene name synonym)|uniprotkb:ESPL1(gene name)|psi-mi:ESPL1(display_short)	psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hellmuth et al. (2014)	pubmed:24781523|imex:IM-23411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9827784|imex:IM-23411-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036423.4|refseq:XP_011537326.1|ensembl:ENSP00000257934|refseq:XP_006719768.1|refseq:XP_016875742.1|dip:DIP-46079N|ensembl:ENST00000257934(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003824"(catalytic activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|reactome:R-HSA-2467813|ensembl:ENSG00000135476(gene)	dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)	-	-	-	figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/10/02	2014/10/16	rogid:oK4Wg46DenILU6xADFkxkybkOcI9606	rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606	intact-crc:CA91DC1AD8720103|rigid:W1UhGGpiu7Eo5gRa6CKhH2OB4D4	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q14674	uniprotkb:O95997	intact:EBI-2554882|intact:EBI-28978215|ensembl:ENSP00000257934	intact:EBI-2551072|ensembl:ENSP00000344936|ensembl:ENSP00000377536|ensembl:ENSP00000430642	psi-mi:espl1_human(display_long)|uniprotkb:ESP1(gene name synonym)|uniprotkb:KIAA0165(gene name synonym)|uniprotkb:Separase(gene name synonym)|uniprotkb:Caspase-like protein ESPL1(gene name synonym)|uniprotkb:Extra spindle poles-like 1 protein(gene name synonym)|uniprotkb:ESPL1(gene name)|psi-mi:ESPL1(display_short)	psi-mi:pttg1_human(display_long)|uniprotkb:EAP1(gene name synonym)|uniprotkb:PTTG(gene name synonym)|uniprotkb:TUTR1(gene name synonym)|uniprotkb:Pituitary tumor-transforming gene 1 protein(gene name synonym)|uniprotkb:Esp1-associated protein(gene name synonym)|uniprotkb:PTTG1(gene name)|psi-mi:PTTG1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hellmuth et al. (2014)	pubmed:24781523|imex:IM-23411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9827784|imex:IM-23411-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036423.4|refseq:XP_011537326.1|ensembl:ENSP00000257934|refseq:XP_006719768.1|refseq:XP_016875742.1|dip:DIP-46079N|ensembl:ENST00000257934(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003824"(catalytic activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|reactome:R-HSA-2467813|ensembl:ENSG00000135476(gene)	ensembl:ENSG00000164611(gene)|ensembl:ENST00000352433(transcript)|ensembl:ENST00000393964(transcript)|ensembl:ENST00000520452(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007283"(spermatogenesis)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:2000816"(negative regulation of mitotic sister chromatid separation)|interpro:IPR006940(Securin sister-chromatid separation inhibitor)|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-2467813|refseq:NP_004210.1|refseq:NP_001269311.1|refseq:NP_001269312.1|dip:DIP-56460N	-	-	-	figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/10/02	2014/10/16	rogid:oK4Wg46DenILU6xADFkxkybkOcI9606	rogid:CsVFdecK6rCfJkLuzlnvom1nsB89606	intact-crc:CA91DC1AD8720103|rigid:W1UhGGpiu7Eo5gRa6CKhH2OB4D4	false	myc tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)