#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P9WF09 uniprotkb:I6Y1Q2 intact:EBI-10091663|uniprotkb:L0TCJ4|uniprotkb:O50387|uniprotkb:P64528 intact:EBI-10091643 psi-mi:relk_myctu(display_long)|uniprotkb:relK(gene name)|psi-mi:relK(display_short)|uniprotkb:relE3(gene name synonym)|uniprotkb:yoeB(gene name synonym)|uniprotkb:Endoribonuclease YoeB(gene name synonym)|uniprotkb:Putative mRNA interferase RelE3(gene name synonym)|uniprotkb:Putative mRNA interferase YoeB(gene name synonym)|uniprotkb:Toxin YoeB(gene name synonym)|uniprotkb:MTV004.15(orf name)|uniprotkb:Rv3358(locus name) psi-mi:i6y1q2_myctu(display_long)|uniprotkb:sirR(gene name)|psi-mi:sirR(display_short)|uniprotkb:Rv2788(locus name) psi-mi:"MI:0018"(two hybrid) Yang et al. (2014) imex:IM-22562|pubmed:24725376 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9354240|imex:IM-22562-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_217875.1|interpro:IPR009614(Addiction module toxin, Txe/YoeB)|rcsb pdb:3OEI|refseq:WP_003417760.1|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016892"(endoribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR035093 refseq:NP_217304.1|interpro:IPR000485(Transcription regulator, AsnC/Lrp)|interpro:IPR007167(Ferrous iron transporter, FeoA subunit)|interpro:IPR001367(Iron dependent repressor)|interpro:IPR022689|interpro:IPR022687|interpro:IPR008988(Transcriptional repressor, C-terminal)|interpro:IPR011991(Winged helix repressor DNA-binding)|refseq:WP_003414136.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR038157|interpro:IPR036388|interpro:IPR036390|interpro:IPR036421|rcsb pdb:5ZR6 - crc64:8663A289B5FD9DAF - figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2014/04/08 2015/01/19 rogid:1EpMaoR6gucQms8AVaTAJjTHkJs83332 rogid:bc+Iqym7RR5c+/NDPzvwug8kcEE83332 intact-crc:CD01F0C682048072|rigid:EqowquaIwjrbBblrT3HXIC4Tlzg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WF25 uniprotkb:P9WF09 intact:EBI-9354099|uniprotkb:P65067|uniprotkb:L0TCA7|uniprotkb:O50386 intact:EBI-10091663|uniprotkb:L0TCJ4|uniprotkb:O50387|uniprotkb:P64528 psi-mi:relj_myctu(display_long)|uniprotkb:relJ(gene name)|psi-mi:relJ(display_short)|uniprotkb:relB3(gene name synonym)|uniprotkb:yefM(gene name synonym)|uniprotkb:Antitoxin YefM(gene name synonym)|uniprotkb:MTV004.14(orf name)|uniprotkb:Rv3357(locus name) psi-mi:relk_myctu(display_long)|uniprotkb:relK(gene name)|psi-mi:relK(display_short)|uniprotkb:relE3(gene name synonym)|uniprotkb:yoeB(gene name synonym)|uniprotkb:Endoribonuclease YoeB(gene name synonym)|uniprotkb:Putative mRNA interferase RelE3(gene name synonym)|uniprotkb:Putative mRNA interferase YoeB(gene name synonym)|uniprotkb:Toxin YoeB(gene name synonym)|uniprotkb:MTV004.15(orf name)|uniprotkb:Rv3358(locus name) psi-mi:"MI:0018"(two hybrid) Yang et al. (2014) imex:IM-22562|pubmed:24725376 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9354097|imex:IM-22562-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_003417757.1|interpro:IPR036165|refseq:NP_217874.1|interpro:IPR006442(Prevent-host-death protein)|rcsb pdb:3CTO|rcsb pdb:3D55|rcsb pdb:3OEI|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated) refseq:NP_217875.1|interpro:IPR009614(Addiction module toxin, Txe/YoeB)|rcsb pdb:3OEI|refseq:WP_003417760.1|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016892"(endoribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR035093 - crc64:5A4140972F329F0A crc64:8663A289B5FD9DAF figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2014/04/08 2015/01/19 rogid:P0VPgQ+0AuE6L/zVfLxcjOdvxV083332 rogid:1EpMaoR6gucQms8AVaTAJjTHkJs83332 intact-crc:6A4DCFA5DB6A0810|rigid:Pmov8887uOMiMVuKF604jxNhuos false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:I6Y1Q2 uniprotkb:P9WF25 intact:EBI-10091643 intact:EBI-9354099|uniprotkb:P65067|uniprotkb:L0TCA7|uniprotkb:O50386 psi-mi:i6y1q2_myctu(display_long)|uniprotkb:sirR(gene name)|psi-mi:sirR(display_short)|uniprotkb:Rv2788(locus name) psi-mi:relj_myctu(display_long)|uniprotkb:relJ(gene name)|psi-mi:relJ(display_short)|uniprotkb:relB3(gene name synonym)|uniprotkb:yefM(gene name synonym)|uniprotkb:Antitoxin YefM(gene name synonym)|uniprotkb:MTV004.14(orf name)|uniprotkb:Rv3357(locus name) psi-mi:"MI:0018"(two hybrid) Yang et al. (2014) imex:IM-22562|pubmed:24725376 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9354209|imex:IM-22562-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_217304.1|interpro:IPR000485(Transcription regulator, AsnC/Lrp)|interpro:IPR007167(Ferrous iron transporter, FeoA subunit)|interpro:IPR001367(Iron dependent repressor)|interpro:IPR022689|interpro:IPR022687|interpro:IPR008988(Transcriptional repressor, C-terminal)|interpro:IPR011991(Winged helix repressor DNA-binding)|refseq:WP_003414136.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR038157|interpro:IPR036388|interpro:IPR036390|interpro:IPR036421|rcsb pdb:5ZR6 refseq:WP_003417757.1|interpro:IPR036165|refseq:NP_217874.1|interpro:IPR006442(Prevent-host-death protein)|rcsb pdb:3CTO|rcsb pdb:3D55|rcsb pdb:3OEI|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated) - - crc64:5A4140972F329F0A figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2014/04/08 2015/01/19 rogid:bc+Iqym7RR5c+/NDPzvwug8kcEE83332 rogid:P0VPgQ+0AuE6L/zVfLxcjOdvxV083332 intact-crc:B55695CE39BEF7FA|rigid:pdyDkZ0sZcd+pHStrZlCP/W6QRo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:I6Y1Q2 uniprotkb:P9WF09 intact:EBI-10091643 intact:EBI-10091663|uniprotkb:L0TCJ4|uniprotkb:O50387|uniprotkb:P64528 psi-mi:i6y1q2_myctu(display_long)|uniprotkb:sirR(gene name)|psi-mi:sirR(display_short)|uniprotkb:Rv2788(locus name) psi-mi:relk_myctu(display_long)|uniprotkb:relK(gene name)|psi-mi:relK(display_short)|uniprotkb:relE3(gene name synonym)|uniprotkb:yoeB(gene name synonym)|uniprotkb:Endoribonuclease YoeB(gene name synonym)|uniprotkb:Putative mRNA interferase RelE3(gene name synonym)|uniprotkb:Putative mRNA interferase YoeB(gene name synonym)|uniprotkb:Toxin YoeB(gene name synonym)|uniprotkb:MTV004.15(orf name)|uniprotkb:Rv3358(locus name) psi-mi:"MI:0096"(pull down) Yang et al. (2014) imex:IM-22562|pubmed:24725376 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9354298|imex:IM-22562-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_217304.1|interpro:IPR000485(Transcription regulator, AsnC/Lrp)|interpro:IPR007167(Ferrous iron transporter, FeoA subunit)|interpro:IPR001367(Iron dependent repressor)|interpro:IPR022689|interpro:IPR022687|interpro:IPR008988(Transcriptional repressor, C-terminal)|interpro:IPR011991(Winged helix repressor DNA-binding)|refseq:WP_003414136.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR038157|interpro:IPR036388|interpro:IPR036390|interpro:IPR036421|rcsb pdb:5ZR6 refseq:NP_217875.1|interpro:IPR009614(Addiction module toxin, Txe/YoeB)|rcsb pdb:3OEI|refseq:WP_003417760.1|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016892"(endoribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR035093 - - crc64:8663A289B5FD9DAF figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/08 2015/01/19 rogid:bc+Iqym7RR5c+/NDPzvwug8kcEE83332 rogid:1EpMaoR6gucQms8AVaTAJjTHkJs83332 intact-crc:1563F6F24BFF0F9A|rigid:EqowquaIwjrbBblrT3HXIC4Tlzg false glutathione s tranferase tag:?-? his tag:?-? - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:I6Y1Q2 uniprotkb:P9WF25 intact:EBI-10091643 intact:EBI-9354099|uniprotkb:P65067|uniprotkb:L0TCA7|uniprotkb:O50386 psi-mi:i6y1q2_myctu(display_long)|uniprotkb:sirR(gene name)|psi-mi:sirR(display_short)|uniprotkb:Rv2788(locus name) psi-mi:relj_myctu(display_long)|uniprotkb:relJ(gene name)|psi-mi:relJ(display_short)|uniprotkb:relB3(gene name synonym)|uniprotkb:yefM(gene name synonym)|uniprotkb:Antitoxin YefM(gene name synonym)|uniprotkb:MTV004.14(orf name)|uniprotkb:Rv3357(locus name) psi-mi:"MI:0096"(pull down) Yang et al. (2014) imex:IM-22562|pubmed:24725376 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9354324|imex:IM-22562-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_217304.1|interpro:IPR000485(Transcription regulator, AsnC/Lrp)|interpro:IPR007167(Ferrous iron transporter, FeoA subunit)|interpro:IPR001367(Iron dependent repressor)|interpro:IPR022689|interpro:IPR022687|interpro:IPR008988(Transcriptional repressor, C-terminal)|interpro:IPR011991(Winged helix repressor DNA-binding)|refseq:WP_003414136.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR038157|interpro:IPR036388|interpro:IPR036390|interpro:IPR036421|rcsb pdb:5ZR6 refseq:WP_003417757.1|interpro:IPR036165|refseq:NP_217874.1|interpro:IPR006442(Prevent-host-death protein)|rcsb pdb:3CTO|rcsb pdb:3D55|rcsb pdb:3OEI|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated) - - crc64:5A4140972F329F0A figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/08 2015/01/19 rogid:bc+Iqym7RR5c+/NDPzvwug8kcEE83332 rogid:P0VPgQ+0AuE6L/zVfLxcjOdvxV083332 intact-crc:E23CF799224F0E81|rigid:pdyDkZ0sZcd+pHStrZlCP/W6QRo false glutathione s tranferase tag:?-? his tag:?-? - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P9WF25 uniprotkb:P9WF09 intact:EBI-9354099|uniprotkb:P65067|uniprotkb:L0TCA7|uniprotkb:O50386 intact:EBI-10091663|uniprotkb:L0TCJ4|uniprotkb:O50387|uniprotkb:P64528 psi-mi:relj_myctu(display_long)|uniprotkb:relJ(gene name)|psi-mi:relJ(display_short)|uniprotkb:relB3(gene name synonym)|uniprotkb:yefM(gene name synonym)|uniprotkb:Antitoxin YefM(gene name synonym)|uniprotkb:MTV004.14(orf name)|uniprotkb:Rv3357(locus name) psi-mi:relk_myctu(display_long)|uniprotkb:relK(gene name)|psi-mi:relK(display_short)|uniprotkb:relE3(gene name synonym)|uniprotkb:yoeB(gene name synonym)|uniprotkb:Endoribonuclease YoeB(gene name synonym)|uniprotkb:Putative mRNA interferase RelE3(gene name synonym)|uniprotkb:Putative mRNA interferase YoeB(gene name synonym)|uniprotkb:Toxin YoeB(gene name synonym)|uniprotkb:MTV004.15(orf name)|uniprotkb:Rv3358(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yang et al. (2014) imex:IM-22562|pubmed:24725376 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9354360|imex:IM-22562-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_003417757.1|interpro:IPR036165|refseq:NP_217874.1|interpro:IPR006442(Prevent-host-death protein)|rcsb pdb:3CTO|rcsb pdb:3D55|rcsb pdb:3OEI|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated) refseq:NP_217875.1|interpro:IPR009614(Addiction module toxin, Txe/YoeB)|rcsb pdb:3OEI|refseq:WP_003417760.1|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016892"(endoribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR035093 - crc64:5A4140972F329F0A crc64:8663A289B5FD9DAF figure legend:f1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:410289(mycbp)|taxid:410289(mycbp) - 2014/04/08 2015/01/19 rogid:P0VPgQ+0AuE6L/zVfLxcjOdvxV083332 rogid:1EpMaoR6gucQms8AVaTAJjTHkJs83332 intact-crc:C845A862B1A2B2D4|rigid:Pmov8887uOMiMVuKF604jxNhuos false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WF25 uniprotkb:P9WF09 intact:EBI-9354099|uniprotkb:P65067|uniprotkb:L0TCA7|uniprotkb:O50386 intact:EBI-10091663|uniprotkb:L0TCJ4|uniprotkb:O50387|uniprotkb:P64528 psi-mi:relj_myctu(display_long)|uniprotkb:relJ(gene name)|psi-mi:relJ(display_short)|uniprotkb:relB3(gene name synonym)|uniprotkb:yefM(gene name synonym)|uniprotkb:Antitoxin YefM(gene name synonym)|uniprotkb:MTV004.14(orf name)|uniprotkb:Rv3357(locus name) psi-mi:relk_myctu(display_long)|uniprotkb:relK(gene name)|psi-mi:relK(display_short)|uniprotkb:relE3(gene name synonym)|uniprotkb:yoeB(gene name synonym)|uniprotkb:Endoribonuclease YoeB(gene name synonym)|uniprotkb:Putative mRNA interferase RelE3(gene name synonym)|uniprotkb:Putative mRNA interferase YoeB(gene name synonym)|uniprotkb:Toxin YoeB(gene name synonym)|uniprotkb:MTV004.15(orf name)|uniprotkb:Rv3358(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yang et al. (2014) imex:IM-22562|pubmed:24725376 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9354385|imex:IM-22562-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_003417757.1|interpro:IPR036165|refseq:NP_217874.1|interpro:IPR006442(Prevent-host-death protein)|rcsb pdb:3CTO|rcsb pdb:3D55|rcsb pdb:3OEI|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated) refseq:NP_217875.1|interpro:IPR009614(Addiction module toxin, Txe/YoeB)|rcsb pdb:3OEI|refseq:WP_003417760.1|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016892"(endoribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR035093 - crc64:5A4140972F329F0A crc64:8663A289B5FD9DAF figure legend:f1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:410289(mycbp)|taxid:410289(mycbp) - 2014/04/08 2015/01/19 rogid:P0VPgQ+0AuE6L/zVfLxcjOdvxV083332 rogid:1EpMaoR6gucQms8AVaTAJjTHkJs83332 intact-crc:E35585D12F85A3CD|rigid:Pmov8887uOMiMVuKF604jxNhuos false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:P9WF25 uniprotkb:I6Y1Q2 intact:EBI-9354099|uniprotkb:P65067|uniprotkb:L0TCA7|uniprotkb:O50386 intact:EBI-10091643 psi-mi:relj_myctu(display_long)|uniprotkb:relJ(gene name)|psi-mi:relJ(display_short)|uniprotkb:relB3(gene name synonym)|uniprotkb:yefM(gene name synonym)|uniprotkb:Antitoxin YefM(gene name synonym)|uniprotkb:MTV004.14(orf name)|uniprotkb:Rv3357(locus name) psi-mi:i6y1q2_myctu(display_long)|uniprotkb:sirR(gene name)|psi-mi:sirR(display_short)|uniprotkb:Rv2788(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yang et al. (2014) imex:IM-22562|pubmed:24725376 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9354354|imex:IM-22562-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_003417757.1|interpro:IPR036165|refseq:NP_217874.1|interpro:IPR006442(Prevent-host-death protein)|rcsb pdb:3CTO|rcsb pdb:3D55|rcsb pdb:3OEI|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated) refseq:NP_217304.1|interpro:IPR000485(Transcription regulator, AsnC/Lrp)|interpro:IPR007167(Ferrous iron transporter, FeoA subunit)|interpro:IPR001367(Iron dependent repressor)|interpro:IPR022689|interpro:IPR022687|interpro:IPR008988(Transcriptional repressor, C-terminal)|interpro:IPR011991(Winged helix repressor DNA-binding)|refseq:WP_003414136.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR038157|interpro:IPR036388|interpro:IPR036390|interpro:IPR036421|rcsb pdb:5ZR6 - crc64:5A4140972F329F0A - figure legend:f1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:410289(mycbp)|taxid:410289(mycbp) - 2014/04/08 2015/01/19 rogid:P0VPgQ+0AuE6L/zVfLxcjOdvxV083332 rogid:bc+Iqym7RR5c+/NDPzvwug8kcEE83332 intact-crc:DC6A5C990C86E644|rigid:pdyDkZ0sZcd+pHStrZlCP/W6QRo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WF09 uniprotkb:I6Y1Q2 intact:EBI-10091663|uniprotkb:L0TCJ4|uniprotkb:O50387|uniprotkb:P64528 intact:EBI-10091643 psi-mi:relk_myctu(display_long)|uniprotkb:relK(gene name)|psi-mi:relK(display_short)|uniprotkb:relE3(gene name synonym)|uniprotkb:yoeB(gene name synonym)|uniprotkb:Endoribonuclease YoeB(gene name synonym)|uniprotkb:Putative mRNA interferase RelE3(gene name synonym)|uniprotkb:Putative mRNA interferase YoeB(gene name synonym)|uniprotkb:Toxin YoeB(gene name synonym)|uniprotkb:MTV004.15(orf name)|uniprotkb:Rv3358(locus name) psi-mi:i6y1q2_myctu(display_long)|uniprotkb:sirR(gene name)|psi-mi:sirR(display_short)|uniprotkb:Rv2788(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yang et al. (2014) imex:IM-22562|pubmed:24725376 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9354348|imex:IM-22562-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_217875.1|interpro:IPR009614(Addiction module toxin, Txe/YoeB)|rcsb pdb:3OEI|refseq:WP_003417760.1|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016892"(endoribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR035093 refseq:NP_217304.1|interpro:IPR000485(Transcription regulator, AsnC/Lrp)|interpro:IPR007167(Ferrous iron transporter, FeoA subunit)|interpro:IPR001367(Iron dependent repressor)|interpro:IPR022689|interpro:IPR022687|interpro:IPR008988(Transcriptional repressor, C-terminal)|interpro:IPR011991(Winged helix repressor DNA-binding)|refseq:WP_003414136.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR038157|interpro:IPR036388|interpro:IPR036390|interpro:IPR036421|rcsb pdb:5ZR6 - crc64:8663A289B5FD9DAF - figure legend:f1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:410289(mycbp)|taxid:410289(mycbp) - 2014/04/08 2015/01/19 rogid:1EpMaoR6gucQms8AVaTAJjTHkJs83332 rogid:bc+Iqym7RR5c+/NDPzvwug8kcEE83332 intact-crc:5889913DA69B765C|rigid:EqowquaIwjrbBblrT3HXIC4Tlzg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant)