#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0ABK2	uniprotkb:P0ABJ9	intact:EBI-1213195|uniprotkb:P11027|ensemblbacteria:AAC73828|ensemblbacteria:BAA35400	intact:EBI-906928|uniprotkb:P11026|uniprotkb:P75754|uniprotkb:P76823|ensemblbacteria:AAC73827|ensemblbacteria:BAA35399	psi-mi:cydb_ecoli(display_long)|uniprotkb:cydB(gene name)|psi-mi:cydB(display_short)|uniprotkb:cyd-2(gene name synonym)|uniprotkb:b0734(locus name)|uniprotkb:JW0723(locus name)|uniprotkb:Cytochrome d ubiquinol oxidase subunit II(gene name synonym)|uniprotkb:Cytochrome bd-I oxidase subunit II(gene name synonym)	psi-mi:cyda_ecoli(display_long)|uniprotkb:cydA(gene name)|psi-mi:cydA(display_short)|uniprotkb:cyd-1(gene name synonym)|uniprotkb:b0733(locus name)|uniprotkb:Cytochrome d ubiquinol oxidase subunit I(gene name synonym)|uniprotkb:Cytochrome bd-I oxidase subunit I(gene name synonym)|uniprotkb:JW0722(locus name)	psi-mi:"MI:0071"(molecular sieving)	Hoeser et al. (2014)	pubmed:24681096|imex:IM-22556	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9258550|imex:IM-22556-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415262.1|interpro:IPR003317(Cytochrome bd ubiquinol oxidase, subunit II)|refseq:WP_000568275.1|ensemblbacteria:AAC73828(transcript)|ensemblbacteria:b0734(gene)|ensemblbacteria:BAA35400(gene)|ensemblbacteria:BAA35400(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016682"(oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor)|go:"GO:0019646"(aerobic electron transport chain)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|rcsb pdb:6RKO|rcsb pdb:6RX4	refseq:NP_415261.2|refseq:WP_000884361.1|dip:DIP-36181N|ensemblbacteria:AAC73827(transcript)|ensemblbacteria:b0733(gene)|ensemblbacteria:BAA35399(gene)|ensemblbacteria:BAA35399(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016679"(oxidoreductase activity, acting on diphenols and related substances as donors)|go:"GO:0016682"(oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor)|go:"GO:0019646"(aerobic electron transport chain)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|interpro:IPR002585(Cytochrome bd ubiquinol oxidase, subunit I)|rcsb pdb:6RKO|rcsb pdb:6RX4	go:"GO:0016020"(membrane)	-	-	figure legend:f1 sf2|comment:"The gel of the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX   obtained by affinity- and size-exclusion chromatography showed two major bands at approximately 54   and 30 kDa. Mass spectrometric analysis revealed that the 54 kDa band corresponds to CydA   (sequence coverage: 37%, overall score: 9865) and the 30 kDa to CydB (sequence coverage: 11%,   overall score: 3576). The relatively low sequence coverage is typical for membrane proteins. No band   with an apparent molecular mass of 4 kDa was detectable in the CBB-stained gel. However, silver   staining revealed the presence of several other bands (Fig. 1). Bands from hydrophobic proteins,   degradation products of CydA and CydB, were detected at about 20 and 8 kDa. Most interestingly,   only the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX showed an additional band   at approximately 5 kDa (Fig. 1). This band corresponds to CydX as revealed by mass spectrometry   (sequence coverage: 67%, overall score: 724)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/18	2014/10/16	rogid:OnzxnVTFfxHvciz8TSjaXgxzz4Y83333	rogid:pq9T4TrY7plPZChTDb34kBbhlgU83333	intact-crc:6F14C9DFD8D1E29C|rigid:AdvsMV2bSWNndZpuafEW/NHUkig	false	-	his tag:?-?	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P0ABJ9	uniprotkb:P0ABK2	intact:EBI-906928|uniprotkb:P11026|uniprotkb:P75754|uniprotkb:P76823|ensemblbacteria:AAC73827|ensemblbacteria:BAA35399	intact:EBI-1213195|uniprotkb:P11027|ensemblbacteria:AAC73828|ensemblbacteria:BAA35400	psi-mi:cyda_ecoli(display_long)|uniprotkb:cydA(gene name)|psi-mi:cydA(display_short)|uniprotkb:cyd-1(gene name synonym)|uniprotkb:b0733(locus name)|uniprotkb:Cytochrome d ubiquinol oxidase subunit I(gene name synonym)|uniprotkb:Cytochrome bd-I oxidase subunit I(gene name synonym)|uniprotkb:JW0722(locus name)	psi-mi:cydb_ecoli(display_long)|uniprotkb:cydB(gene name)|psi-mi:cydB(display_short)|uniprotkb:cyd-2(gene name synonym)|uniprotkb:b0734(locus name)|uniprotkb:JW0723(locus name)|uniprotkb:Cytochrome d ubiquinol oxidase subunit II(gene name synonym)|uniprotkb:Cytochrome bd-I oxidase subunit II(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Hoeser et al. (2014)	pubmed:24681096|imex:IM-22556	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9258537|imex:IM-22556-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415261.2|refseq:WP_000884361.1|dip:DIP-36181N|ensemblbacteria:AAC73827(transcript)|ensemblbacteria:b0733(gene)|ensemblbacteria:BAA35399(gene)|ensemblbacteria:BAA35399(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016679"(oxidoreductase activity, acting on diphenols and related substances as donors)|go:"GO:0016682"(oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor)|go:"GO:0019646"(aerobic electron transport chain)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|interpro:IPR002585(Cytochrome bd ubiquinol oxidase, subunit I)|rcsb pdb:6RKO|rcsb pdb:6RX4	refseq:NP_415262.1|interpro:IPR003317(Cytochrome bd ubiquinol oxidase, subunit II)|refseq:WP_000568275.1|ensemblbacteria:AAC73828(transcript)|ensemblbacteria:b0734(gene)|ensemblbacteria:BAA35400(gene)|ensemblbacteria:BAA35400(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016682"(oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor)|go:"GO:0019646"(aerobic electron transport chain)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|rcsb pdb:6RKO|rcsb pdb:6RX4	go:"GO:0016020"(membrane)	-	-	figure legend:f1 sf2|comment:"The gel of the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX   obtained by affinity- and size-exclusion chromatography showed two major bands at approximately 54   and 30 kDa. Mass spectrometric analysis revealed that the 54 kDa band corresponds to CydA   (sequence coverage: 37%, overall score: 9865) and the 30 kDa to CydB (sequence coverage: 11%,   overall score: 3576). The relatively low sequence coverage is typical for membrane proteins. No band   with an apparent molecular mass of 4 kDa was detectable in the CBB-stained gel. However, silver   staining revealed the presence of several other bands (Fig. 1). Bands from hydrophobic proteins,   degradation products of CydA and CydB, were detected at about 20 and 8 kDa. Most interestingly,   only the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX showed an additional band   at approximately 5 kDa (Fig. 1). This band corresponds to CydX as revealed by mass spectrometry   (sequence coverage: 67%, overall score: 724)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/18	2015/09/12	rogid:pq9T4TrY7plPZChTDb34kBbhlgU83333	rogid:OnzxnVTFfxHvciz8TSjaXgxzz4Y83333	intact-crc:EAF004800C7DAD48|rigid:uh/rDfj43ura3qYHfqshsAR77gE	false	his tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P0ABJ9	uniprotkb:P56100	intact:EBI-906928|uniprotkb:P11026|uniprotkb:P75754|uniprotkb:P76823|ensemblbacteria:AAC73827|ensemblbacteria:BAA35399	intact:EBI-9258541|uniprotkb:Q2EER0|uniprotkb:Q2MBJ7|ensemblbacteria:ABD18645|ensemblbacteria:BAE76359	psi-mi:cyda_ecoli(display_long)|uniprotkb:cydA(gene name)|psi-mi:cydA(display_short)|uniprotkb:cyd-1(gene name synonym)|uniprotkb:b0733(locus name)|uniprotkb:Cytochrome d ubiquinol oxidase subunit I(gene name synonym)|uniprotkb:Cytochrome bd-I oxidase subunit I(gene name synonym)|uniprotkb:JW0722(locus name)	psi-mi:cydx_ecoli(display_long)|uniprotkb:cydX(gene name)|psi-mi:cydX(display_short)|uniprotkb:Cytochrome bd-I oxidase subunit X(gene name synonym)|uniprotkb:Cytochrome d ubiquinol oxidase subunit X(gene name synonym)|uniprotkb:ybgT(gene name synonym)|uniprotkb:JW0724(locus name)|uniprotkb:b4515(locus name)	psi-mi:"MI:0071"(molecular sieving)	Hoeser et al. (2014)	pubmed:24681096|imex:IM-22556	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9258537|imex:IM-22556-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415261.2|refseq:WP_000884361.1|dip:DIP-36181N|ensemblbacteria:AAC73827(transcript)|ensemblbacteria:b0733(gene)|ensemblbacteria:BAA35399(gene)|ensemblbacteria:BAA35399(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016679"(oxidoreductase activity, acting on diphenols and related substances as donors)|go:"GO:0016682"(oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor)|go:"GO:0019646"(aerobic electron transport chain)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|interpro:IPR002585(Cytochrome bd ubiquinol oxidase, subunit I)|rcsb pdb:6RKO|rcsb pdb:6RX4	refseq:WP_000270282.1|interpro:IPR011724(Cyd operon protein YbgT)|interpro:IPR012994(Membrane bound YbgT-like)|refseq:YP_588444.1|rcsb pdb:6RKO|rcsb pdb:6RX4|ensemblbacteria:ABD18645(transcript)|ensemblbacteria:b4515(gene)|ensemblbacteria:BAE76359(gene)|ensemblbacteria:BAE76359(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0016679"(oxidoreductase activity, acting on diphenols and related substances as donors)|go:"GO:0019867"(outer membrane)	go:"GO:0016020"(membrane)	-	-	figure legend:f1 sf2|comment:"The gel of the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX   obtained by affinity- and size-exclusion chromatography showed two major bands at approximately 54   and 30 kDa. Mass spectrometric analysis revealed that the 54 kDa band corresponds to CydA   (sequence coverage: 37%, overall score: 9865) and the 30 kDa to CydB (sequence coverage: 11%,   overall score: 3576). The relatively low sequence coverage is typical for membrane proteins. No band   with an apparent molecular mass of 4 kDa was detectable in the CBB-stained gel. However, silver   staining revealed the presence of several other bands (Fig. 1). Bands from hydrophobic proteins,   degradation products of CydA and CydB, were detected at about 20 and 8 kDa. Most interestingly,   only the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX showed an additional band   at approximately 5 kDa (Fig. 1). This band corresponds to CydX as revealed by mass spectrometry   (sequence coverage: 67%, overall score: 724)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/18	2015/09/12	rogid:pq9T4TrY7plPZChTDb34kBbhlgU83333	rogid:TP3wjY583qPPRGQqKvldPKC6pbY83333	intact-crc:EAF004800C7DAD48|rigid:uh/rDfj43ura3qYHfqshsAR77gE	false	his tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P56100	uniprotkb:P0ABJ9	intact:EBI-9258541|uniprotkb:Q2EER0|uniprotkb:Q2MBJ7|ensemblbacteria:ABD18645|ensemblbacteria:BAE76359	intact:EBI-906928|uniprotkb:P11026|uniprotkb:P75754|uniprotkb:P76823|ensemblbacteria:AAC73827|ensemblbacteria:BAA35399	psi-mi:cydx_ecoli(display_long)|uniprotkb:cydX(gene name)|psi-mi:cydX(display_short)|uniprotkb:Cytochrome bd-I oxidase subunit X(gene name synonym)|uniprotkb:Cytochrome d ubiquinol oxidase subunit X(gene name synonym)|uniprotkb:ybgT(gene name synonym)|uniprotkb:JW0724(locus name)|uniprotkb:b4515(locus name)	psi-mi:cyda_ecoli(display_long)|uniprotkb:cydA(gene name)|psi-mi:cydA(display_short)|uniprotkb:cyd-1(gene name synonym)|uniprotkb:b0733(locus name)|uniprotkb:Cytochrome d ubiquinol oxidase subunit I(gene name synonym)|uniprotkb:Cytochrome bd-I oxidase subunit I(gene name synonym)|uniprotkb:JW0722(locus name)	psi-mi:"MI:0400"(affinity technology)	Hoeser et al. (2014)	pubmed:24681096|imex:IM-22556	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9258591|imex:IM-22556-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000270282.1|interpro:IPR011724(Cyd operon protein YbgT)|interpro:IPR012994(Membrane bound YbgT-like)|refseq:YP_588444.1|rcsb pdb:6RKO|rcsb pdb:6RX4|ensemblbacteria:ABD18645(transcript)|ensemblbacteria:b4515(gene)|ensemblbacteria:BAE76359(gene)|ensemblbacteria:BAE76359(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0016679"(oxidoreductase activity, acting on diphenols and related substances as donors)|go:"GO:0019867"(outer membrane)	refseq:NP_415261.2|refseq:WP_000884361.1|dip:DIP-36181N|ensemblbacteria:AAC73827(transcript)|ensemblbacteria:b0733(gene)|ensemblbacteria:BAA35399(gene)|ensemblbacteria:BAA35399(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016679"(oxidoreductase activity, acting on diphenols and related substances as donors)|go:"GO:0016682"(oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor)|go:"GO:0019646"(aerobic electron transport chain)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|interpro:IPR002585(Cytochrome bd ubiquinol oxidase, subunit I)|rcsb pdb:6RKO|rcsb pdb:6RX4	go:"GO:0016020"(membrane)	-	-	figure legend:f3a|comment:"The gel of the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX   obtained by affinity- and size-exclusion chromatography showed two major bands at approximately 54   and 30 kDa. Mass spectrometric analysis revealed that the 54 kDa band corresponds to CydA   (sequence coverage: 37%, overall score: 9865) and the 30 kDa to CydB (sequence coverage: 11%,   overall score: 3576). The relatively low sequence coverage is typical for membrane proteins. No band   with an apparent molecular mass of 4 kDa was detectable in the CBB-stained gel. However, silver   staining revealed the presence of several other bands (Fig. 1). Bands from hydrophobic proteins,   degradation products of CydA and CydB, were detected at about 20 and 8 kDa. Most interestingly,   only the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX showed an additional band   at approximately 5 kDa (Fig. 1). This band corresponds to CydX as revealed by mass spectrometry   (sequence coverage: 67%, overall score: 724)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/18	2014/10/16	rogid:TP3wjY583qPPRGQqKvldPKC6pbY83333	rogid:pq9T4TrY7plPZChTDb34kBbhlgU83333	intact-crc:8C1972C93128DED4|rigid:uh/rDfj43ura3qYHfqshsAR77gE	false	strep tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P56100	uniprotkb:P0ABK2	intact:EBI-9258541|uniprotkb:Q2EER0|uniprotkb:Q2MBJ7|ensemblbacteria:ABD18645|ensemblbacteria:BAE76359	intact:EBI-1213195|uniprotkb:P11027|ensemblbacteria:AAC73828|ensemblbacteria:BAA35400	psi-mi:cydx_ecoli(display_long)|uniprotkb:cydX(gene name)|psi-mi:cydX(display_short)|uniprotkb:Cytochrome bd-I oxidase subunit X(gene name synonym)|uniprotkb:Cytochrome d ubiquinol oxidase subunit X(gene name synonym)|uniprotkb:ybgT(gene name synonym)|uniprotkb:JW0724(locus name)|uniprotkb:b4515(locus name)	psi-mi:cydb_ecoli(display_long)|uniprotkb:cydB(gene name)|psi-mi:cydB(display_short)|uniprotkb:cyd-2(gene name synonym)|uniprotkb:b0734(locus name)|uniprotkb:JW0723(locus name)|uniprotkb:Cytochrome d ubiquinol oxidase subunit II(gene name synonym)|uniprotkb:Cytochrome bd-I oxidase subunit II(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Hoeser et al. (2014)	pubmed:24681096|imex:IM-22556	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9258591|imex:IM-22556-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000270282.1|interpro:IPR011724(Cyd operon protein YbgT)|interpro:IPR012994(Membrane bound YbgT-like)|refseq:YP_588444.1|rcsb pdb:6RKO|rcsb pdb:6RX4|ensemblbacteria:ABD18645(transcript)|ensemblbacteria:b4515(gene)|ensemblbacteria:BAE76359(gene)|ensemblbacteria:BAE76359(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0016679"(oxidoreductase activity, acting on diphenols and related substances as donors)|go:"GO:0019867"(outer membrane)	refseq:NP_415262.1|interpro:IPR003317(Cytochrome bd ubiquinol oxidase, subunit II)|refseq:WP_000568275.1|ensemblbacteria:AAC73828(transcript)|ensemblbacteria:b0734(gene)|ensemblbacteria:BAA35400(gene)|ensemblbacteria:BAA35400(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016682"(oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor)|go:"GO:0019646"(aerobic electron transport chain)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|rcsb pdb:6RKO|rcsb pdb:6RX4	go:"GO:0016020"(membrane)	-	-	figure legend:f3a|comment:"The gel of the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX   obtained by affinity- and size-exclusion chromatography showed two major bands at approximately 54   and 30 kDa. Mass spectrometric analysis revealed that the 54 kDa band corresponds to CydA   (sequence coverage: 37%, overall score: 9865) and the 30 kDa to CydB (sequence coverage: 11%,   overall score: 3576). The relatively low sequence coverage is typical for membrane proteins. No band   with an apparent molecular mass of 4 kDa was detectable in the CBB-stained gel. However, silver   staining revealed the presence of several other bands (Fig. 1). Bands from hydrophobic proteins,   degradation products of CydA and CydB, were detected at about 20 and 8 kDa. Most interestingly,   only the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX showed an additional band   at approximately 5 kDa (Fig. 1). This band corresponds to CydX as revealed by mass spectrometry   (sequence coverage: 67%, overall score: 724)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/18	2014/10/16	rogid:TP3wjY583qPPRGQqKvldPKC6pbY83333	rogid:OnzxnVTFfxHvciz8TSjaXgxzz4Y83333	intact-crc:8C1972C93128DED4|rigid:uh/rDfj43ura3qYHfqshsAR77gE	false	strep tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P0ABJ9	uniprotkb:P56100	intact:EBI-906928|uniprotkb:P11026|uniprotkb:P75754|uniprotkb:P76823|ensemblbacteria:AAC73827|ensemblbacteria:BAA35399	intact:EBI-9258541|uniprotkb:Q2EER0|uniprotkb:Q2MBJ7|ensemblbacteria:ABD18645|ensemblbacteria:BAE76359	psi-mi:cyda_ecoli(display_long)|uniprotkb:cydA(gene name)|psi-mi:cydA(display_short)|uniprotkb:cyd-1(gene name synonym)|uniprotkb:b0733(locus name)|uniprotkb:Cytochrome d ubiquinol oxidase subunit I(gene name synonym)|uniprotkb:Cytochrome bd-I oxidase subunit I(gene name synonym)|uniprotkb:JW0722(locus name)	psi-mi:cydx_ecoli(display_long)|uniprotkb:cydX(gene name)|psi-mi:cydX(display_short)|uniprotkb:Cytochrome bd-I oxidase subunit X(gene name synonym)|uniprotkb:Cytochrome d ubiquinol oxidase subunit X(gene name synonym)|uniprotkb:ybgT(gene name synonym)|uniprotkb:JW0724(locus name)|uniprotkb:b4515(locus name)	psi-mi:"MI:0400"(affinity technology)	Hoeser et al. (2014)	pubmed:24681096|imex:IM-22556	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9258579|imex:IM-22556-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415261.2|refseq:WP_000884361.1|dip:DIP-36181N|ensemblbacteria:AAC73827(transcript)|ensemblbacteria:b0733(gene)|ensemblbacteria:BAA35399(gene)|ensemblbacteria:BAA35399(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016679"(oxidoreductase activity, acting on diphenols and related substances as donors)|go:"GO:0016682"(oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor)|go:"GO:0019646"(aerobic electron transport chain)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|interpro:IPR002585(Cytochrome bd ubiquinol oxidase, subunit I)|rcsb pdb:6RKO|rcsb pdb:6RX4	refseq:WP_000270282.1|interpro:IPR011724(Cyd operon protein YbgT)|interpro:IPR012994(Membrane bound YbgT-like)|refseq:YP_588444.1|rcsb pdb:6RKO|rcsb pdb:6RX4|ensemblbacteria:ABD18645(transcript)|ensemblbacteria:b4515(gene)|ensemblbacteria:BAE76359(gene)|ensemblbacteria:BAE76359(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0016679"(oxidoreductase activity, acting on diphenols and related substances as donors)|go:"GO:0019867"(outer membrane)	go:"GO:0016020"(membrane)	-	-	figure legend:f1 sf2|comment:"The gel of the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX   obtained by affinity- and size-exclusion chromatography showed two major bands at approximately 54   and 30 kDa. Mass spectrometric analysis revealed that the 54 kDa band corresponds to CydA   (sequence coverage: 37%, overall score: 9865) and the 30 kDa to CydB (sequence coverage: 11%,   overall score: 3576). The relatively low sequence coverage is typical for membrane proteins. No band   with an apparent molecular mass of 4 kDa was detectable in the CBB-stained gel. However, silver   staining revealed the presence of several other bands (Fig. 1). Bands from hydrophobic proteins,   degradation products of CydA and CydB, were detected at about 20 and 8 kDa. Most interestingly,   only the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX showed an additional band   at approximately 5 kDa (Fig. 1). This band corresponds to CydX as revealed by mass spectrometry   (sequence coverage: 67%, overall score: 724)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/18	2014/10/16	rogid:pq9T4TrY7plPZChTDb34kBbhlgU83333	rogid:TP3wjY583qPPRGQqKvldPKC6pbY83333	intact-crc:A23DB012AC445055|rigid:uh/rDfj43ura3qYHfqshsAR77gE	false	his tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P0ABJ9	uniprotkb:P0ABK2	intact:EBI-906928|uniprotkb:P11026|uniprotkb:P75754|uniprotkb:P76823|ensemblbacteria:AAC73827|ensemblbacteria:BAA35399	intact:EBI-1213195|uniprotkb:P11027|ensemblbacteria:AAC73828|ensemblbacteria:BAA35400	psi-mi:cyda_ecoli(display_long)|uniprotkb:cydA(gene name)|psi-mi:cydA(display_short)|uniprotkb:cyd-1(gene name synonym)|uniprotkb:b0733(locus name)|uniprotkb:Cytochrome d ubiquinol oxidase subunit I(gene name synonym)|uniprotkb:Cytochrome bd-I oxidase subunit I(gene name synonym)|uniprotkb:JW0722(locus name)	psi-mi:cydb_ecoli(display_long)|uniprotkb:cydB(gene name)|psi-mi:cydB(display_short)|uniprotkb:cyd-2(gene name synonym)|uniprotkb:b0734(locus name)|uniprotkb:JW0723(locus name)|uniprotkb:Cytochrome d ubiquinol oxidase subunit II(gene name synonym)|uniprotkb:Cytochrome bd-I oxidase subunit II(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Hoeser et al. (2014)	pubmed:24681096|imex:IM-22556	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9258579|imex:IM-22556-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415261.2|refseq:WP_000884361.1|dip:DIP-36181N|ensemblbacteria:AAC73827(transcript)|ensemblbacteria:b0733(gene)|ensemblbacteria:BAA35399(gene)|ensemblbacteria:BAA35399(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016679"(oxidoreductase activity, acting on diphenols and related substances as donors)|go:"GO:0016682"(oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor)|go:"GO:0019646"(aerobic electron transport chain)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|interpro:IPR002585(Cytochrome bd ubiquinol oxidase, subunit I)|rcsb pdb:6RKO|rcsb pdb:6RX4	refseq:NP_415262.1|interpro:IPR003317(Cytochrome bd ubiquinol oxidase, subunit II)|refseq:WP_000568275.1|ensemblbacteria:AAC73828(transcript)|ensemblbacteria:b0734(gene)|ensemblbacteria:BAA35400(gene)|ensemblbacteria:BAA35400(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016682"(oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor)|go:"GO:0019646"(aerobic electron transport chain)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|rcsb pdb:6RKO|rcsb pdb:6RX4	go:"GO:0016020"(membrane)	-	-	figure legend:f1 sf2|comment:"The gel of the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX   obtained by affinity- and size-exclusion chromatography showed two major bands at approximately 54   and 30 kDa. Mass spectrometric analysis revealed that the 54 kDa band corresponds to CydA   (sequence coverage: 37%, overall score: 9865) and the 30 kDa to CydB (sequence coverage: 11%,   overall score: 3576). The relatively low sequence coverage is typical for membrane proteins. No band   with an apparent molecular mass of 4 kDa was detectable in the CBB-stained gel. However, silver   staining revealed the presence of several other bands (Fig. 1). Bands from hydrophobic proteins,   degradation products of CydA and CydB, were detected at about 20 and 8 kDa. Most interestingly,   only the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX showed an additional band   at approximately 5 kDa (Fig. 1). This band corresponds to CydX as revealed by mass spectrometry   (sequence coverage: 67%, overall score: 724)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/18	2014/10/16	rogid:pq9T4TrY7plPZChTDb34kBbhlgU83333	rogid:OnzxnVTFfxHvciz8TSjaXgxzz4Y83333	intact-crc:A23DB012AC445055|rigid:uh/rDfj43ura3qYHfqshsAR77gE	false	his tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P0ABK2	uniprotkb:P0ABJ9	intact:EBI-1213195|uniprotkb:P11027|ensemblbacteria:AAC73828|ensemblbacteria:BAA35400	intact:EBI-906928|uniprotkb:P11026|uniprotkb:P75754|uniprotkb:P76823|ensemblbacteria:AAC73827|ensemblbacteria:BAA35399	psi-mi:cydb_ecoli(display_long)|uniprotkb:cydB(gene name)|psi-mi:cydB(display_short)|uniprotkb:cyd-2(gene name synonym)|uniprotkb:b0734(locus name)|uniprotkb:JW0723(locus name)|uniprotkb:Cytochrome d ubiquinol oxidase subunit II(gene name synonym)|uniprotkb:Cytochrome bd-I oxidase subunit II(gene name synonym)	psi-mi:cyda_ecoli(display_long)|uniprotkb:cydA(gene name)|psi-mi:cydA(display_short)|uniprotkb:cyd-1(gene name synonym)|uniprotkb:b0733(locus name)|uniprotkb:Cytochrome d ubiquinol oxidase subunit I(gene name synonym)|uniprotkb:Cytochrome bd-I oxidase subunit I(gene name synonym)|uniprotkb:JW0722(locus name)	psi-mi:"MI:0400"(affinity technology)	Hoeser et al. (2014)	pubmed:24681096|imex:IM-22556	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9258569|imex:IM-22556-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415262.1|interpro:IPR003317(Cytochrome bd ubiquinol oxidase, subunit II)|refseq:WP_000568275.1|ensemblbacteria:AAC73828(transcript)|ensemblbacteria:b0734(gene)|ensemblbacteria:BAA35400(gene)|ensemblbacteria:BAA35400(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016682"(oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor)|go:"GO:0019646"(aerobic electron transport chain)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|rcsb pdb:6RKO|rcsb pdb:6RX4	refseq:NP_415261.2|refseq:WP_000884361.1|dip:DIP-36181N|ensemblbacteria:AAC73827(transcript)|ensemblbacteria:b0733(gene)|ensemblbacteria:BAA35399(gene)|ensemblbacteria:BAA35399(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016679"(oxidoreductase activity, acting on diphenols and related substances as donors)|go:"GO:0016682"(oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor)|go:"GO:0019646"(aerobic electron transport chain)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070069"(cytochrome complex)|interpro:IPR002585(Cytochrome bd ubiquinol oxidase, subunit I)|rcsb pdb:6RKO|rcsb pdb:6RX4	go:"GO:0016020"(membrane)	-	-	figure legend:f1 sf1|comment:"The gel of the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX   obtained by affinity- and size-exclusion chromatography showed two major bands at approximately 54   and 30 kDa. Mass spectrometric analysis revealed that the 54 kDa band corresponds to CydA   (sequence coverage: 37%, overall score: 9865) and the 30 kDa to CydB (sequence coverage: 11%,   overall score: 3576). The relatively low sequence coverage is typical for membrane proteins. No band   with an apparent molecular mass of 4 kDa was detectable in the CBB-stained gel. However, silver   staining revealed the presence of several other bands (Fig. 1). Bands from hydrophobic proteins,   degradation products of CydA and CydB, were detected at about 20 and 8 kDa. Most interestingly,   only the preparation of the bd oxidase from strain CBO/pET28 cydAhisBX showed an additional band   at approximately 5 kDa (Fig. 1). This band corresponds to CydX as revealed by mass spectrometry   (sequence coverage: 67%, overall score: 724)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/18	2014/10/16	rogid:OnzxnVTFfxHvciz8TSjaXgxzz4Y83333	rogid:pq9T4TrY7plPZChTDb34kBbhlgU83333	intact-crc:07D6FBA437BEF8E8|rigid:AdvsMV2bSWNndZpuafEW/NHUkig	false	-	his tag:?-?	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)