#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q6RVA9	uniprotkb:P30555	intact:EBI-10042432|uniprotkb:Q0PHA2|uniprotkb:Q2QLE1	intact:EBI-10042398|ensembl:ENSSSCP00000030853|ensembl:ENSSSCP00005020902|ensembl:ENSSSCP00015028872|ensembl:ENSSSCP00025016487|ensembl:ENSSSCP00030028191|ensembl:ENSSSCP00035003286|ensembl:ENSSSCP00040042920|ensembl:ENSSSCP00045038876|ensembl:ENSSSCP00050033335|ensembl:ENSSSCP00055034160|ensembl:ENSSSCP00060037272|ensembl:ENSSSCP00065042773|ensembl:ENSSSCP00070009438	psi-mi:cav1_pig(display_long)|uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)	psi-mi:agtr1_pig(display_long)|uniprotkb:AGTR1(gene name)|psi-mi:AGTR1(display_short)|uniprotkb:Angiotensin II type-1 receptor(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Adebiyi et al. (2014)	pubmed:24662198|imex:IM-23562	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10042396|imex:IM-23562-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001612(Caveolin)|interpro:IPR018361|go:"GO:0000139"(Golgi membrane)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070836"(caveola assembly)|go:"GO:0045121"(membrane raft)|interpro:IPR015504(Caveolin-1)|refseq:NP_999603.1	refseq:XP_003132517.1|ensembl:ENSSSCG00000011695|reactome:R-SSC-8856828|ensembl:ENSSSCG00000011695(gene)|ensembl:ENSSSCG00005021724(gene)|ensembl:ENSSSCG00015053993(gene)|ensembl:ENSSSCG00025028692(gene)|ensembl:ENSSSCG00030044196(gene)|ensembl:ENSSSCG00035007839(gene)|ensembl:ENSSSCG00040070419(gene)|ensembl:ENSSSCG00045032665(gene)|ensembl:ENSSSCG00050056820(gene)|ensembl:ENSSSCG00055021872(gene)|ensembl:ENSSSCG00060063200(gene)|ensembl:ENSSSCG00065071012(gene)|ensembl:ENSSSCG00070006005(gene)|ensembl:ENSSSCT00000034453(transcript)|ensembl:ENSSSCT00005034302(transcript)|ensembl:ENSSSCT00015071980(transcript)|ensembl:ENSSSCT00025038974(transcript)|ensembl:ENSSSCT00030061647(transcript)|ensembl:ENSSSCT00035009753(transcript)|ensembl:ENSSSCT00040096595(transcript)|ensembl:ENSSSCT00045055743(transcript)|ensembl:ENSSSCT00050077460(transcript)|ensembl:ENSSSCT00055042939(transcript)|ensembl:ENSSSCT00060086211(transcript)|ensembl:ENSSSCT00065097576(transcript)|ensembl:ENSSSCT00070011447(transcript)|go:"GO:0001596"(angiotensin type I receptor activity)|go:"GO:0001822"(kidney development)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0031711"(bradykinin receptor binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|interpro:IPR000190(AT1 angiotensin II receptor)|interpro:IPR000248(Angiotensin II receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-SSC-375276|reactome:R-SSC-416476|reactome:R-SSC-8856825	go:"GO:0005886"(plasma membrane)	-	-	figure legend:6C|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-kidney-mesangial_cell)|taxid:9823(Sus scrofa kidney-mesangial_cell)	-	2014/12/15	2014/12/15	rogid:G6pQaQBGKLy/wWWpOkJwtRHE5sU9823	rogid:wF7izslGyyMz1v6mscBObUA1teM9823	intact-crc:79A0942A921F9F03|rigid:8yNed7D0nGQh4497ImyxBPoeu68	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q6RVA9	uniprotkb:P30555	intact:EBI-10042432|uniprotkb:Q0PHA2|uniprotkb:Q2QLE1	intact:EBI-10042398|ensembl:ENSSSCP00000030853|ensembl:ENSSSCP00005020902|ensembl:ENSSSCP00015028872|ensembl:ENSSSCP00025016487|ensembl:ENSSSCP00030028191|ensembl:ENSSSCP00035003286|ensembl:ENSSSCP00040042920|ensembl:ENSSSCP00045038876|ensembl:ENSSSCP00050033335|ensembl:ENSSSCP00055034160|ensembl:ENSSSCP00060037272|ensembl:ENSSSCP00065042773|ensembl:ENSSSCP00070009438	psi-mi:cav1_pig(display_long)|uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)	psi-mi:agtr1_pig(display_long)|uniprotkb:AGTR1(gene name)|psi-mi:AGTR1(display_short)|uniprotkb:Angiotensin II type-1 receptor(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Adebiyi et al. (2014)	pubmed:24662198|imex:IM-23562	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10042531|imex:IM-23562-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001612(Caveolin)|interpro:IPR018361|go:"GO:0000139"(Golgi membrane)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070836"(caveola assembly)|go:"GO:0045121"(membrane raft)|interpro:IPR015504(Caveolin-1)|refseq:NP_999603.1	refseq:XP_003132517.1|ensembl:ENSSSCG00000011695|reactome:R-SSC-8856828|ensembl:ENSSSCG00000011695(gene)|ensembl:ENSSSCG00005021724(gene)|ensembl:ENSSSCG00015053993(gene)|ensembl:ENSSSCG00025028692(gene)|ensembl:ENSSSCG00030044196(gene)|ensembl:ENSSSCG00035007839(gene)|ensembl:ENSSSCG00040070419(gene)|ensembl:ENSSSCG00045032665(gene)|ensembl:ENSSSCG00050056820(gene)|ensembl:ENSSSCG00055021872(gene)|ensembl:ENSSSCG00060063200(gene)|ensembl:ENSSSCG00065071012(gene)|ensembl:ENSSSCG00070006005(gene)|ensembl:ENSSSCT00000034453(transcript)|ensembl:ENSSSCT00005034302(transcript)|ensembl:ENSSSCT00015071980(transcript)|ensembl:ENSSSCT00025038974(transcript)|ensembl:ENSSSCT00030061647(transcript)|ensembl:ENSSSCT00035009753(transcript)|ensembl:ENSSSCT00040096595(transcript)|ensembl:ENSSSCT00045055743(transcript)|ensembl:ENSSSCT00050077460(transcript)|ensembl:ENSSSCT00055042939(transcript)|ensembl:ENSSSCT00060086211(transcript)|ensembl:ENSSSCT00065097576(transcript)|ensembl:ENSSSCT00070011447(transcript)|go:"GO:0001596"(angiotensin type I receptor activity)|go:"GO:0001822"(kidney development)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0031711"(bradykinin receptor binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|interpro:IPR000190(AT1 angiotensin II receptor)|interpro:IPR000248(Angiotensin II receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-SSC-375276|reactome:R-SSC-416476|reactome:R-SSC-8856825	-	-	-	figure legend:6D|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-kidney-mesangial_cell)|taxid:9823(Sus scrofa kidney-mesangial_cell)	-	2014/12/15	2014/12/15	rogid:G6pQaQBGKLy/wWWpOkJwtRHE5sU9823	rogid:wF7izslGyyMz1v6mscBObUA1teM9823	intact-crc:5E5C13BEB532E49B|rigid:8yNed7D0nGQh4497ImyxBPoeu68	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)