#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P20491	uniprotkb:Q62120	intact:EBI-9306159|ensembl:ENSMUSP00000078875	intact:EBI-646604|uniprotkb:Q7TQD0|uniprotkb:Q62124|intact:EBI-16039126|ensembl:ENSMUSP00000025705|ensembl:ENSMUSP00000064394|ensembl:ENSMUSP00000158242|uniprotkb:G5E852	psi-mi:fcerg_mouse(display_long)|uniprotkb:Fcer1g(gene name)|psi-mi:Fcer1g(display_short)|uniprotkb:Fce1g(gene name synonym)|uniprotkb:Fc receptor gamma-chain(gene name synonym)|uniprotkb:Fc-epsilon RI-gamma(gene name synonym)|uniprotkb:IgE Fc receptor subunit gamma(gene name synonym)	psi-mi:jak2_mouse(display_long)|uniprotkb:Janus kinase 2(gene name synonym)|uniprotkb:Jak2(gene name)|psi-mi:Jak2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bezbradica et al. (2014)	imex:IM-22293|pubmed:24608040	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-9306200|imex:IM-22293-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034315.1|ensembl:ENSMUSG00000058715(gene)|ensembl:ENSMUST00000079957(transcript)|go:"GO:0001798"(positive regulation of type IIa hypersensitivity)|go:"GO:0001805"(positive regulation of type III hypersensitivity)|go:"GO:0001812"(positive regulation of type I hypersensitivity)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002292"(T cell differentiation involved in immune response)|go:"GO:0002431"(Fc receptor mediated stimulatory signaling pathway)|go:"GO:0002554"(serotonin secretion by platelet)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019767"(IgE receptor activity)|go:"GO:0019863"(IgE binding)|go:"GO:0019864"(IgG binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031623"(receptor internalization)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032765"(positive regulation of mast cell cytokine production)|go:"GO:0032998"(Fc-epsilon receptor I complex)|go:"GO:0033026"(negative regulation of mast cell apoptotic process)|go:"GO:0038094"(Fc-gamma receptor signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038156"(interleukin-3-mediated signaling pathway)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045576"(mast cell activation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|interpro:IPR042340|reactome:R-MMU-114604|reactome:R-MMU-202733|reactome:R-MMU-2454202|reactome:R-MMU-2730905|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-2871837|reactome:R-MMU-5621480|reactome:R-MMU-6798695|reactome:R-MMU-75892	refseq:NP_001041642.1|refseq:NP_032439.2|dip:DIP-320N|ensembl:ENSMUSG00000024789(gene)|ensembl:ENSMUST00000025705(transcript)|ensembl:ENSMUST00000065796(transcript)|ensembl:ENSMUST00000238009(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0000791"(euchromatin)|go:"GO:0001774"(microglial cell activation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050867"(positive regulation of cell activation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060399"(positive regulation of growth hormone receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070671"(response to interleukin-12)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097012"(response to granulocyte macrophage colony-stimulating factor)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0098794"(postsynapse)|interpro:IPR019749|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031959"(mineralocorticoid receptor signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0020037"(heme binding)|interpro:IPR020693|interpro:IPR035588|interpro:IPR035589|interpro:IPR035860|interpro:IPR035963|interpro:IPR036860|interpro:IPR037838|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:Q62120|rcsb pdb:2HDX|rcsb pdb:4GL9|reactome:R-MMU-1059683|reactome:R-MMU-110056|interpro:IPR020635|reactome:R-MMU-112411|reactome:R-MMU-1170546|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0035401"("histone kinase activity (H3-Y41 specific)")|go:"GO:0035409"(histone H3-Y41 phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0034050"(programmed cell death induced by symbiont)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005143"(interleukin-12 receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007167"(enzyme linked receptor protein signaling pathway)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|reactome:R-MMU-512988|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-6785807|reactome:R-MMU-6788467|reactome:R-MMU-69231|reactome:R-MMU-877300|reactome:R-MMU-877312|reactome:R-MMU-8854691|reactome:R-MMU-8984722|reactome:R-MMU-9020591|reactome:R-MMU-9020933|reactome:R-MMU-9020956|reactome:R-MMU-9027276|reactome:R-MMU-9027284|reactome:R-MMU-912526|reactome:R-MMU-9674555|reactome:R-MMU-9705462|reactome:R-MMU-982772|reactome:R-MMU-983231|reactome:R-MMU-1433557|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0012505"(endomembrane system)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-60238N|refseq:XP_011245457.1	-	-	-	figure legend:Figure 1c, 1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2014/03/26	2021/02/11	rogid:LR8Zs3DbStFa/1fuja2rIL8fysw10090	rogid:pdjCNCHmNTiJ1gGtJyiWoGgtq4I10090	intact-crc:E4B439FD4EF2DBB7|rigid:m4H3YVU4WbfyUwS1TpOI71V5Hyg	false	flag tag:n-n	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q62120	uniprotkb:P20491	intact:EBI-646604|uniprotkb:Q7TQD0|uniprotkb:Q62124|intact:EBI-16039126|ensembl:ENSMUSP00000025705|ensembl:ENSMUSP00000064394|ensembl:ENSMUSP00000158242|uniprotkb:G5E852	intact:EBI-9306159|ensembl:ENSMUSP00000078875	psi-mi:jak2_mouse(display_long)|uniprotkb:Janus kinase 2(gene name synonym)|uniprotkb:Jak2(gene name)|psi-mi:Jak2(display_short)	psi-mi:fcerg_mouse(display_long)|uniprotkb:Fcer1g(gene name)|psi-mi:Fcer1g(display_short)|uniprotkb:Fce1g(gene name synonym)|uniprotkb:Fc receptor gamma-chain(gene name synonym)|uniprotkb:Fc-epsilon RI-gamma(gene name synonym)|uniprotkb:IgE Fc receptor subunit gamma(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bezbradica et al. (2014)	imex:IM-22293|pubmed:24608040	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-9307519|imex:IM-22293-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001041642.1|refseq:NP_032439.2|dip:DIP-320N|ensembl:ENSMUSG00000024789(gene)|ensembl:ENSMUST00000025705(transcript)|ensembl:ENSMUST00000065796(transcript)|ensembl:ENSMUST00000238009(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0000791"(euchromatin)|go:"GO:0001774"(microglial cell activation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050867"(positive regulation of cell activation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060399"(positive regulation of growth hormone receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070671"(response to interleukin-12)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097012"(response to granulocyte macrophage colony-stimulating factor)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0098794"(postsynapse)|interpro:IPR019749|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031959"(mineralocorticoid receptor signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0020037"(heme binding)|interpro:IPR020693|interpro:IPR035588|interpro:IPR035589|interpro:IPR035860|interpro:IPR035963|interpro:IPR036860|interpro:IPR037838|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:Q62120|rcsb pdb:2HDX|rcsb pdb:4GL9|reactome:R-MMU-1059683|reactome:R-MMU-110056|interpro:IPR020635|reactome:R-MMU-112411|reactome:R-MMU-1170546|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0035401"("histone kinase activity (H3-Y41 specific)")|go:"GO:0035409"(histone H3-Y41 phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0034050"(programmed cell death induced by symbiont)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005143"(interleukin-12 receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007167"(enzyme linked receptor protein signaling pathway)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|reactome:R-MMU-512988|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-6785807|reactome:R-MMU-6788467|reactome:R-MMU-69231|reactome:R-MMU-877300|reactome:R-MMU-877312|reactome:R-MMU-8854691|reactome:R-MMU-8984722|reactome:R-MMU-9020591|reactome:R-MMU-9020933|reactome:R-MMU-9020956|reactome:R-MMU-9027276|reactome:R-MMU-9027284|reactome:R-MMU-912526|reactome:R-MMU-9674555|reactome:R-MMU-9705462|reactome:R-MMU-982772|reactome:R-MMU-983231|reactome:R-MMU-1433557|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0012505"(endomembrane system)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-60238N|refseq:XP_011245457.1	refseq:NP_034315.1|ensembl:ENSMUSG00000058715(gene)|ensembl:ENSMUST00000079957(transcript)|go:"GO:0001798"(positive regulation of type IIa hypersensitivity)|go:"GO:0001805"(positive regulation of type III hypersensitivity)|go:"GO:0001812"(positive regulation of type I hypersensitivity)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002292"(T cell differentiation involved in immune response)|go:"GO:0002431"(Fc receptor mediated stimulatory signaling pathway)|go:"GO:0002554"(serotonin secretion by platelet)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019767"(IgE receptor activity)|go:"GO:0019863"(IgE binding)|go:"GO:0019864"(IgG binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031623"(receptor internalization)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032765"(positive regulation of mast cell cytokine production)|go:"GO:0032998"(Fc-epsilon receptor I complex)|go:"GO:0033026"(negative regulation of mast cell apoptotic process)|go:"GO:0038094"(Fc-gamma receptor signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038156"(interleukin-3-mediated signaling pathway)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045576"(mast cell activation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|interpro:IPR042340|reactome:R-MMU-114604|reactome:R-MMU-202733|reactome:R-MMU-2454202|reactome:R-MMU-2730905|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-2871837|reactome:R-MMU-5621480|reactome:R-MMU-6798695|reactome:R-MMU-75892	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2014/03/26	2021/02/11	rogid:pdjCNCHmNTiJ1gGtJyiWoGgtq4I10090	rogid:LR8Zs3DbStFa/1fuja2rIL8fysw10090	intact-crc:F8831B5AAF315B49|rigid:m4H3YVU4WbfyUwS1TpOI71V5Hyg	false	ha tag:c-c	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)