#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O15392 uniprotkb:Q96GD4 intact:EBI-518823|uniprotkb:B2R4R1|uniprotkb:Q2I3N8|uniprotkb:Q4VGX0|uniprotkb:Q53F61|uniprotkb:Q5MGC6|uniprotkb:Q6FHL2|uniprotkb:Q75SP2|uniprotkb:Q9P2W8|intact:EBI-979338|uniprotkb:A2SUH6 intact:EBI-624291|uniprotkb:O14630|uniprotkb:O60446|uniprotkb:O95083|uniprotkb:Q96DV5|uniprotkb:Q9UQ46|ensembl:ENSP00000463999|uniprotkb:B4DNM4|uniprotkb:D3DTR4|uniprotkb:C7G533|uniprotkb:C7G534|uniprotkb:C7G535|uniprotkb:J9JID1 psi-mi:birc5_human(display_long)|uniprotkb:Apoptosis inhibitor survivin(gene name synonym)|uniprotkb:Apoptosis inhibitor 4(gene name synonym)|uniprotkb:BIRC5(gene name)|psi-mi:BIRC5(display_short)|uniprotkb:API4(gene name synonym)|uniprotkb:IAP4(gene name synonym) psi-mi:aurkb_human(display_long)|uniprotkb:AIRK2(gene name synonym)|uniprotkb:Aurora- and IPL1-like midbody-associated protein 1(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 2(gene name synonym)|uniprotkb:STK-1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 5(gene name synonym)|uniprotkb:STK1(gene name synonym)|uniprotkb:STK5(gene name synonym)|uniprotkb:Aurora 1(gene name synonym)|uniprotkb:AURKB(gene name)|psi-mi:AURKB(display_short)|uniprotkb:AIK2(gene name synonym)|uniprotkb:AIM1(gene name synonym)|uniprotkb:ARK2(gene name synonym)|uniprotkb:STK12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fackler et al. (2014) pubmed:24571573|imex:IM-22545 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9248183|imex:IM-22545-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001012270.1|refseq:NP_001012271.1|refseq:NP_001159.2|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015631"(tubulin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030496"(midbody)|go:"GO:0031021"(interphase microtubule organizing center)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031503"(protein-containing complex localization)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|rcsb pdb:1E31|rcsb pdb:1F3H|rcsb pdb:1XOX|rcsb pdb:2QFA|rcsb pdb:2RAW|rcsb pdb:2RAX|rcsb pdb:3UEC|rcsb pdb:3UED|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UEG|rcsb pdb:3UEH|rcsb pdb:3UEI|rcsb pdb:3UIG|rcsb pdb:3UIH|rcsb pdb:3UII|rcsb pdb:3UIJ|rcsb pdb:3UIK|rcsb pdb:4A0I|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:6SHO|rcsb pdb:6YIE|rcsb pdb:6YIF|rcsb pdb:6YIH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-68877|reactome:R-HSA-8951664|reactome:R-HSA-9648025|mint:O15392|dip:DIP-34662N go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007568"(aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009838"(abscission)|go:"GO:0010369"(chromocenter)|go:"GO:0016570"(histone modification)|go:"GO:0019900"(kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0004674"(protein serine/threonine kinase activity)|ensembl:ENSG00000178999(gene)|ensembl:ENST00000585124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|refseq:NP_001271455.1|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1905116"(positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028772|interpro:IPR030616|mint:Q96GD4|rcsb pdb:4AF3|reactome:R-HSA-141444|reactome:R-HSA-174178|reactome:R-HSA-2467813|reactome:R-HSA-2500257|go:"GO:0051973"(positive regulation of telomerase activity)|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-6804756|reactome:R-HSA-68877|reactome:R-HSA-9022692|reactome:R-HSA-9648025|refseq:NP_004208.2|refseq:NP_001243763.1|refseq:NP_001300879.1|refseq:NP_001300880.1|refseq:NP_001300881.1|refseq:NP_001300882.1|refseq:NP_001300883.1|refseq:NP_001300884.1|refseq:XP_011522372.1|refseq:XP_011522374.1|refseq:XP_016880796.1|dip:DIP-34530N - - - figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2014/02/27 2014/10/16 rogid:tfya/9aPPiS0zmJOVSP6EdN8XGM9606 rogid:4pmZhSoAp5JmH19k2tT+w3z9Hgo9606 intact-crc:FA97E689044B8118|rigid:SS6Ffs09oWjgfrgzGPK3rocUtYM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O15392 uniprotkb:Q86XJ1 intact:EBI-518823|uniprotkb:B2R4R1|uniprotkb:Q2I3N8|uniprotkb:Q4VGX0|uniprotkb:Q53F61|uniprotkb:Q5MGC6|uniprotkb:Q6FHL2|uniprotkb:Q75SP2|uniprotkb:Q9P2W8|intact:EBI-979338|uniprotkb:A2SUH6 intact:EBI-9248152|uniprotkb:B2RCN2|ensembl:ENSP00000266754|ensembl:ENSP00000439672|ensembl:ENSP00000448955 psi-mi:birc5_human(display_long)|uniprotkb:Apoptosis inhibitor survivin(gene name synonym)|uniprotkb:Apoptosis inhibitor 4(gene name synonym)|uniprotkb:BIRC5(gene name)|psi-mi:BIRC5(display_short)|uniprotkb:API4(gene name synonym)|uniprotkb:IAP4(gene name synonym) psi-mi:ga2l3_human(display_long)|uniprotkb:GAS2L3(gene name)|psi-mi:GAS2L3(display_short)|uniprotkb:Growth arrest-specific protein 2-like 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fackler et al. (2014) pubmed:24571573|imex:IM-22545 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9248183|imex:IM-22545-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001012270.1|refseq:NP_001012271.1|refseq:NP_001159.2|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015631"(tubulin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030496"(midbody)|go:"GO:0031021"(interphase microtubule organizing center)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031503"(protein-containing complex localization)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|rcsb pdb:1E31|rcsb pdb:1F3H|rcsb pdb:1XOX|rcsb pdb:2QFA|rcsb pdb:2RAW|rcsb pdb:2RAX|rcsb pdb:3UEC|rcsb pdb:3UED|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UEG|rcsb pdb:3UEH|rcsb pdb:3UEI|rcsb pdb:3UIG|rcsb pdb:3UIH|rcsb pdb:3UII|rcsb pdb:3UIJ|rcsb pdb:3UIK|rcsb pdb:4A0I|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:6SHO|rcsb pdb:6YIE|rcsb pdb:6YIF|rcsb pdb:6YIH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-68877|reactome:R-HSA-8951664|reactome:R-HSA-9648025|mint:O15392|dip:DIP-34662N refseq:NP_001290059.1|refseq:NP_777602.1|refseq:XP_005268861.1|refseq:XP_011536521.1|refseq:XP_011536522.1|refseq:XP_011536523.1|refseq:XP_016874695.1|ensembl:ENSG00000139354(gene)|ensembl:ENST00000266754(transcript)|ensembl:ENST00000539410(transcript)|ensembl:ENST00000547754(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR029932|interpro:IPR036534|interpro:IPR036872 - - - figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2014/02/27 2014/10/16 rogid:tfya/9aPPiS0zmJOVSP6EdN8XGM9606 rogid:faSiTYyhbHi2HBh52UIaeYm5kFA9606 intact-crc:FA97E689044B8118|rigid:SS6Ffs09oWjgfrgzGPK3rocUtYM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XJ1 uniprotkb:O15392 intact:EBI-9248152|uniprotkb:B2RCN2|ensembl:ENSP00000266754|ensembl:ENSP00000439672|ensembl:ENSP00000448955 intact:EBI-518823|uniprotkb:B2R4R1|uniprotkb:Q2I3N8|uniprotkb:Q4VGX0|uniprotkb:Q53F61|uniprotkb:Q5MGC6|uniprotkb:Q6FHL2|uniprotkb:Q75SP2|uniprotkb:Q9P2W8|intact:EBI-979338|uniprotkb:A2SUH6 psi-mi:ga2l3_human(display_long)|uniprotkb:GAS2L3(gene name)|psi-mi:GAS2L3(display_short)|uniprotkb:Growth arrest-specific protein 2-like 3(gene name synonym) psi-mi:birc5_human(display_long)|uniprotkb:Apoptosis inhibitor survivin(gene name synonym)|uniprotkb:Apoptosis inhibitor 4(gene name synonym)|uniprotkb:BIRC5(gene name)|psi-mi:BIRC5(display_short)|uniprotkb:API4(gene name synonym)|uniprotkb:IAP4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fackler et al. (2014) pubmed:24571573|imex:IM-22545 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9248148|imex:IM-22545-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290059.1|refseq:NP_777602.1|refseq:XP_005268861.1|refseq:XP_011536521.1|refseq:XP_011536522.1|refseq:XP_011536523.1|refseq:XP_016874695.1|ensembl:ENSG00000139354(gene)|ensembl:ENST00000266754(transcript)|ensembl:ENST00000539410(transcript)|ensembl:ENST00000547754(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR029932|interpro:IPR036534|interpro:IPR036872 refseq:NP_001012270.1|refseq:NP_001012271.1|refseq:NP_001159.2|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015631"(tubulin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030496"(midbody)|go:"GO:0031021"(interphase microtubule organizing center)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031503"(protein-containing complex localization)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|rcsb pdb:1E31|rcsb pdb:1F3H|rcsb pdb:1XOX|rcsb pdb:2QFA|rcsb pdb:2RAW|rcsb pdb:2RAX|rcsb pdb:3UEC|rcsb pdb:3UED|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UEG|rcsb pdb:3UEH|rcsb pdb:3UEI|rcsb pdb:3UIG|rcsb pdb:3UIH|rcsb pdb:3UII|rcsb pdb:3UIJ|rcsb pdb:3UIK|rcsb pdb:4A0I|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:6SHO|rcsb pdb:6YIE|rcsb pdb:6YIF|rcsb pdb:6YIH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-68877|reactome:R-HSA-8951664|reactome:R-HSA-9648025|mint:O15392|dip:DIP-34662N - - - figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2014/02/27 2014/10/16 rogid:faSiTYyhbHi2HBh52UIaeYm5kFA9606 rogid:tfya/9aPPiS0zmJOVSP6EdN8XGM9606 intact-crc:27399457069F7E41|rigid:SS6Ffs09oWjgfrgzGPK3rocUtYM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XJ1 uniprotkb:Q96GD4 intact:EBI-9248152|uniprotkb:B2RCN2|ensembl:ENSP00000266754|ensembl:ENSP00000439672|ensembl:ENSP00000448955 intact:EBI-624291|uniprotkb:O14630|uniprotkb:O60446|uniprotkb:O95083|uniprotkb:Q96DV5|uniprotkb:Q9UQ46|ensembl:ENSP00000463999|uniprotkb:B4DNM4|uniprotkb:D3DTR4|uniprotkb:C7G533|uniprotkb:C7G534|uniprotkb:C7G535|uniprotkb:J9JID1 psi-mi:ga2l3_human(display_long)|uniprotkb:GAS2L3(gene name)|psi-mi:GAS2L3(display_short)|uniprotkb:Growth arrest-specific protein 2-like 3(gene name synonym) psi-mi:aurkb_human(display_long)|uniprotkb:AIRK2(gene name synonym)|uniprotkb:Aurora- and IPL1-like midbody-associated protein 1(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 2(gene name synonym)|uniprotkb:STK-1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 5(gene name synonym)|uniprotkb:STK1(gene name synonym)|uniprotkb:STK5(gene name synonym)|uniprotkb:Aurora 1(gene name synonym)|uniprotkb:AURKB(gene name)|psi-mi:AURKB(display_short)|uniprotkb:AIK2(gene name synonym)|uniprotkb:AIM1(gene name synonym)|uniprotkb:ARK2(gene name synonym)|uniprotkb:STK12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fackler et al. (2014) pubmed:24571573|imex:IM-22545 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9248148|imex:IM-22545-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290059.1|refseq:NP_777602.1|refseq:XP_005268861.1|refseq:XP_011536521.1|refseq:XP_011536522.1|refseq:XP_011536523.1|refseq:XP_016874695.1|ensembl:ENSG00000139354(gene)|ensembl:ENST00000266754(transcript)|ensembl:ENST00000539410(transcript)|ensembl:ENST00000547754(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR029932|interpro:IPR036534|interpro:IPR036872 go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007568"(aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009838"(abscission)|go:"GO:0010369"(chromocenter)|go:"GO:0016570"(histone modification)|go:"GO:0019900"(kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0004674"(protein serine/threonine kinase activity)|ensembl:ENSG00000178999(gene)|ensembl:ENST00000585124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|refseq:NP_001271455.1|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1905116"(positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028772|interpro:IPR030616|mint:Q96GD4|rcsb pdb:4AF3|reactome:R-HSA-141444|reactome:R-HSA-174178|reactome:R-HSA-2467813|reactome:R-HSA-2500257|go:"GO:0051973"(positive regulation of telomerase activity)|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-6804756|reactome:R-HSA-68877|reactome:R-HSA-9022692|reactome:R-HSA-9648025|refseq:NP_004208.2|refseq:NP_001243763.1|refseq:NP_001300879.1|refseq:NP_001300880.1|refseq:NP_001300881.1|refseq:NP_001300882.1|refseq:NP_001300883.1|refseq:NP_001300884.1|refseq:XP_011522372.1|refseq:XP_011522374.1|refseq:XP_016880796.1|dip:DIP-34530N - - - figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2014/02/27 2014/10/16 rogid:faSiTYyhbHi2HBh52UIaeYm5kFA9606 rogid:4pmZhSoAp5JmH19k2tT+w3z9Hgo9606 intact-crc:27399457069F7E41|rigid:SS6Ffs09oWjgfrgzGPK3rocUtYM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XJ1 uniprotkb:Q96GD4 intact:EBI-9248152|uniprotkb:B2RCN2|ensembl:ENSP00000266754|ensembl:ENSP00000439672|ensembl:ENSP00000448955 intact:EBI-624291|uniprotkb:O14630|uniprotkb:O60446|uniprotkb:O95083|uniprotkb:Q96DV5|uniprotkb:Q9UQ46|ensembl:ENSP00000463999|uniprotkb:B4DNM4|uniprotkb:D3DTR4|uniprotkb:C7G533|uniprotkb:C7G534|uniprotkb:C7G535|uniprotkb:J9JID1 psi-mi:ga2l3_human(display_long)|uniprotkb:GAS2L3(gene name)|psi-mi:GAS2L3(display_short)|uniprotkb:Growth arrest-specific protein 2-like 3(gene name synonym) psi-mi:aurkb_human(display_long)|uniprotkb:AIRK2(gene name synonym)|uniprotkb:Aurora- and IPL1-like midbody-associated protein 1(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 2(gene name synonym)|uniprotkb:STK-1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 5(gene name synonym)|uniprotkb:STK1(gene name synonym)|uniprotkb:STK5(gene name synonym)|uniprotkb:Aurora 1(gene name synonym)|uniprotkb:AURKB(gene name)|psi-mi:AURKB(display_short)|uniprotkb:AIK2(gene name synonym)|uniprotkb:AIM1(gene name synonym)|uniprotkb:ARK2(gene name synonym)|uniprotkb:STK12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-B(gene name synonym) psi-mi:"MI:0096"(pull down) Fackler et al. (2014) pubmed:24571573|imex:IM-22545 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9248204|imex:IM-22545-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290059.1|refseq:NP_777602.1|refseq:XP_005268861.1|refseq:XP_011536521.1|refseq:XP_011536522.1|refseq:XP_011536523.1|refseq:XP_016874695.1|ensembl:ENSG00000139354(gene)|ensembl:ENST00000266754(transcript)|ensembl:ENST00000539410(transcript)|ensembl:ENST00000547754(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR029932|interpro:IPR036534|interpro:IPR036872 go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007568"(aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009838"(abscission)|go:"GO:0010369"(chromocenter)|go:"GO:0016570"(histone modification)|go:"GO:0019900"(kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0004674"(protein serine/threonine kinase activity)|ensembl:ENSG00000178999(gene)|ensembl:ENST00000585124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|refseq:NP_001271455.1|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1905116"(positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028772|interpro:IPR030616|mint:Q96GD4|rcsb pdb:4AF3|reactome:R-HSA-141444|reactome:R-HSA-174178|reactome:R-HSA-2467813|reactome:R-HSA-2500257|go:"GO:0051973"(positive regulation of telomerase activity)|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-6804756|reactome:R-HSA-68877|reactome:R-HSA-9022692|reactome:R-HSA-9648025|refseq:NP_004208.2|refseq:NP_001243763.1|refseq:NP_001300879.1|refseq:NP_001300880.1|refseq:NP_001300881.1|refseq:NP_001300882.1|refseq:NP_001300883.1|refseq:NP_001300884.1|refseq:XP_011522372.1|refseq:XP_011522374.1|refseq:XP_016880796.1|dip:DIP-34530N - - - figure legend:f2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/02/27 2014/10/16 rogid:faSiTYyhbHi2HBh52UIaeYm5kFA9606 rogid:4pmZhSoAp5JmH19k2tT+w3z9Hgo9606 intact-crc:2FE7CFC0BD30EAE9|rigid:6H3IbJxhpUhKdaq4GmWibKVHGLE false glutathione s tranferase tag:?-?|binding-associated region:170-310 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XJ1 uniprotkb:O15392 intact:EBI-9248152|uniprotkb:B2RCN2|ensembl:ENSP00000266754|ensembl:ENSP00000439672|ensembl:ENSP00000448955 intact:EBI-518823|uniprotkb:B2R4R1|uniprotkb:Q2I3N8|uniprotkb:Q4VGX0|uniprotkb:Q53F61|uniprotkb:Q5MGC6|uniprotkb:Q6FHL2|uniprotkb:Q75SP2|uniprotkb:Q9P2W8|intact:EBI-979338|uniprotkb:A2SUH6 psi-mi:ga2l3_human(display_long)|uniprotkb:GAS2L3(gene name)|psi-mi:GAS2L3(display_short)|uniprotkb:Growth arrest-specific protein 2-like 3(gene name synonym) psi-mi:birc5_human(display_long)|uniprotkb:Apoptosis inhibitor survivin(gene name synonym)|uniprotkb:Apoptosis inhibitor 4(gene name synonym)|uniprotkb:BIRC5(gene name)|psi-mi:BIRC5(display_short)|uniprotkb:API4(gene name synonym)|uniprotkb:IAP4(gene name synonym) psi-mi:"MI:0096"(pull down) Fackler et al. (2014) pubmed:24571573|imex:IM-22545 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9248219|imex:IM-22545-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290059.1|refseq:NP_777602.1|refseq:XP_005268861.1|refseq:XP_011536521.1|refseq:XP_011536522.1|refseq:XP_011536523.1|refseq:XP_016874695.1|ensembl:ENSG00000139354(gene)|ensembl:ENST00000266754(transcript)|ensembl:ENST00000539410(transcript)|ensembl:ENST00000547754(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR029932|interpro:IPR036534|interpro:IPR036872 refseq:NP_001012270.1|refseq:NP_001012271.1|refseq:NP_001159.2|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015631"(tubulin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030496"(midbody)|go:"GO:0031021"(interphase microtubule organizing center)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031503"(protein-containing complex localization)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|rcsb pdb:1E31|rcsb pdb:1F3H|rcsb pdb:1XOX|rcsb pdb:2QFA|rcsb pdb:2RAW|rcsb pdb:2RAX|rcsb pdb:3UEC|rcsb pdb:3UED|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UEG|rcsb pdb:3UEH|rcsb pdb:3UEI|rcsb pdb:3UIG|rcsb pdb:3UIH|rcsb pdb:3UII|rcsb pdb:3UIJ|rcsb pdb:3UIK|rcsb pdb:4A0I|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:6SHO|rcsb pdb:6YIE|rcsb pdb:6YIF|rcsb pdb:6YIH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-68877|reactome:R-HSA-8951664|reactome:R-HSA-9648025|mint:O15392|dip:DIP-34662N - - - figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/02/27 2014/10/16 rogid:faSiTYyhbHi2HBh52UIaeYm5kFA9606 rogid:tfya/9aPPiS0zmJOVSP6EdN8XGM9606 intact-crc:6D4C4F15C1FD3FC2|rigid:wRr185yIvxnMMq4W20QVteIAS1Y false glutathione s tranferase tag:?-?|binding-associated region:170-310 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XJ1 uniprotkb:Q53HL2 intact:EBI-9248152|uniprotkb:B2RCN2|ensembl:ENSP00000266754|ensembl:ENSP00000439672|ensembl:ENSP00000448955 intact:EBI-979174|uniprotkb:Q53HN1|uniprotkb:Q96AM3|uniprotkb:Q9NVW5|ensembl:ENSP00000316121|ensembl:ENSP00000362146|intact:EBI-2557781|uniprotkb:D3DPT4 psi-mi:ga2l3_human(display_long)|uniprotkb:GAS2L3(gene name)|psi-mi:GAS2L3(display_short)|uniprotkb:Growth arrest-specific protein 2-like 3(gene name synonym) psi-mi:borea_human(display_long)|uniprotkb:Dasra-B(gene name synonym)|uniprotkb:Cell division cycle-associated protein 8(gene name synonym)|uniprotkb:Pluripotent embryonic stem cell-related gene 3 protein(gene name synonym)|uniprotkb:CDCA8(gene name)|psi-mi:CDCA8(display_short)|uniprotkb:PESCRG3(gene name synonym) psi-mi:"MI:0096"(pull down) Fackler et al. (2014) pubmed:24571573|imex:IM-22545 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9248219|imex:IM-22545-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290059.1|refseq:NP_777602.1|refseq:XP_005268861.1|refseq:XP_011536521.1|refseq:XP_011536522.1|refseq:XP_011536523.1|refseq:XP_016874695.1|ensembl:ENSG00000139354(gene)|ensembl:ENST00000266754(transcript)|ensembl:ENST00000539410(transcript)|ensembl:ENST00000547754(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR029932|interpro:IPR036534|interpro:IPR036872 rcsb pdb:6YIH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000327331(transcript)|ensembl:ENST00000373055(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0010369"(chromocenter)|go:"GO:0030496"(midbody)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|interpro:IPR018851|interpro:IPR018867|mint:Q53HL2|rcsb pdb:2KDD|rcsb pdb:2QFA|rcsb pdb:2RAW|ensembl:ENSG00000134690(gene)|rcsb pdb:2RAX|rcsb pdb:6YIE|rcsb pdb:6YIF|refseq:NP_001243804.1|refseq:NP_060571.1|dip:DIP-37995N - - - figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/02/27 2014/10/16 rogid:faSiTYyhbHi2HBh52UIaeYm5kFA9606 rogid:LdL29UIjy+IvQfWTwvatWPabuq09606 intact-crc:6D4C4F15C1FD3FC2|rigid:wRr185yIvxnMMq4W20QVteIAS1Y false glutathione s tranferase tag:?-?|binding-associated region:170-310 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XJ1 uniprotkb:Q96GD4 intact:EBI-9248152|uniprotkb:B2RCN2|ensembl:ENSP00000266754|ensembl:ENSP00000439672|ensembl:ENSP00000448955 intact:EBI-624291|uniprotkb:O14630|uniprotkb:O60446|uniprotkb:O95083|uniprotkb:Q96DV5|uniprotkb:Q9UQ46|ensembl:ENSP00000463999|uniprotkb:B4DNM4|uniprotkb:D3DTR4|uniprotkb:C7G533|uniprotkb:C7G534|uniprotkb:C7G535|uniprotkb:J9JID1 psi-mi:ga2l3_human(display_long)|uniprotkb:GAS2L3(gene name)|psi-mi:GAS2L3(display_short)|uniprotkb:Growth arrest-specific protein 2-like 3(gene name synonym) psi-mi:aurkb_human(display_long)|uniprotkb:AIRK2(gene name synonym)|uniprotkb:Aurora- and IPL1-like midbody-associated protein 1(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 2(gene name synonym)|uniprotkb:STK-1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 5(gene name synonym)|uniprotkb:STK1(gene name synonym)|uniprotkb:STK5(gene name synonym)|uniprotkb:Aurora 1(gene name synonym)|uniprotkb:AURKB(gene name)|psi-mi:AURKB(display_short)|uniprotkb:AIK2(gene name synonym)|uniprotkb:AIM1(gene name synonym)|uniprotkb:ARK2(gene name synonym)|uniprotkb:STK12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-B(gene name synonym) psi-mi:"MI:0096"(pull down) Fackler et al. (2014) pubmed:24571573|imex:IM-22545 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9248219|imex:IM-22545-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290059.1|refseq:NP_777602.1|refseq:XP_005268861.1|refseq:XP_011536521.1|refseq:XP_011536522.1|refseq:XP_011536523.1|refseq:XP_016874695.1|ensembl:ENSG00000139354(gene)|ensembl:ENST00000266754(transcript)|ensembl:ENST00000539410(transcript)|ensembl:ENST00000547754(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR029932|interpro:IPR036534|interpro:IPR036872 go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007568"(aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009838"(abscission)|go:"GO:0010369"(chromocenter)|go:"GO:0016570"(histone modification)|go:"GO:0019900"(kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0004674"(protein serine/threonine kinase activity)|ensembl:ENSG00000178999(gene)|ensembl:ENST00000585124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|refseq:NP_001271455.1|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1905116"(positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028772|interpro:IPR030616|mint:Q96GD4|rcsb pdb:4AF3|reactome:R-HSA-141444|reactome:R-HSA-174178|reactome:R-HSA-2467813|reactome:R-HSA-2500257|go:"GO:0051973"(positive regulation of telomerase activity)|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-6804756|reactome:R-HSA-68877|reactome:R-HSA-9022692|reactome:R-HSA-9648025|refseq:NP_004208.2|refseq:NP_001243763.1|refseq:NP_001300879.1|refseq:NP_001300880.1|refseq:NP_001300881.1|refseq:NP_001300882.1|refseq:NP_001300883.1|refseq:NP_001300884.1|refseq:XP_011522372.1|refseq:XP_011522374.1|refseq:XP_016880796.1|dip:DIP-34530N - - - figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/02/27 2014/10/16 rogid:faSiTYyhbHi2HBh52UIaeYm5kFA9606 rogid:4pmZhSoAp5JmH19k2tT+w3z9Hgo9606 intact-crc:6D4C4F15C1FD3FC2|rigid:wRr185yIvxnMMq4W20QVteIAS1Y false glutathione s tranferase tag:?-?|binding-associated region:170-310 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0113"(western blot) uniprotkb:O15392 uniprotkb:Q86XJ1 intact:EBI-518823|uniprotkb:B2R4R1|uniprotkb:Q2I3N8|uniprotkb:Q4VGX0|uniprotkb:Q53F61|uniprotkb:Q5MGC6|uniprotkb:Q6FHL2|uniprotkb:Q75SP2|uniprotkb:Q9P2W8|intact:EBI-979338|uniprotkb:A2SUH6 intact:EBI-9248152|uniprotkb:B2RCN2|ensembl:ENSP00000266754|ensembl:ENSP00000439672|ensembl:ENSP00000448955 psi-mi:birc5_human(display_long)|uniprotkb:Apoptosis inhibitor survivin(gene name synonym)|uniprotkb:Apoptosis inhibitor 4(gene name synonym)|uniprotkb:BIRC5(gene name)|psi-mi:BIRC5(display_short)|uniprotkb:API4(gene name synonym)|uniprotkb:IAP4(gene name synonym) psi-mi:ga2l3_human(display_long)|uniprotkb:GAS2L3(gene name)|psi-mi:GAS2L3(display_short)|uniprotkb:Growth arrest-specific protein 2-like 3(gene name synonym) psi-mi:"MI:0096"(pull down) Fackler et al. (2014) pubmed:24571573|imex:IM-22545 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9248233|imex:IM-22545-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001012270.1|refseq:NP_001012271.1|refseq:NP_001159.2|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015631"(tubulin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030496"(midbody)|go:"GO:0031021"(interphase microtubule organizing center)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031503"(protein-containing complex localization)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|rcsb pdb:1E31|rcsb pdb:1F3H|rcsb pdb:1XOX|rcsb pdb:2QFA|rcsb pdb:2RAW|rcsb pdb:2RAX|rcsb pdb:3UEC|rcsb pdb:3UED|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UEG|rcsb pdb:3UEH|rcsb pdb:3UEI|rcsb pdb:3UIG|rcsb pdb:3UIH|rcsb pdb:3UII|rcsb pdb:3UIJ|rcsb pdb:3UIK|rcsb pdb:4A0I|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:6SHO|rcsb pdb:6YIE|rcsb pdb:6YIF|rcsb pdb:6YIH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-68877|reactome:R-HSA-8951664|reactome:R-HSA-9648025|mint:O15392|dip:DIP-34662N refseq:NP_001290059.1|refseq:NP_777602.1|refseq:XP_005268861.1|refseq:XP_011536521.1|refseq:XP_011536522.1|refseq:XP_011536523.1|refseq:XP_016874695.1|ensembl:ENSG00000139354(gene)|ensembl:ENST00000266754(transcript)|ensembl:ENST00000539410(transcript)|ensembl:ENST00000547754(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR029932|interpro:IPR036534|interpro:IPR036872 - - - figure legend:f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/02/27 2014/10/16 rogid:tfya/9aPPiS0zmJOVSP6EdN8XGM9606 rogid:faSiTYyhbHi2HBh52UIaeYm5kFA9606 intact-crc:734D76220F74DAEF|rigid:RI3rKcZF9VnH4arYsG+x1VF4CuM false his tag:?-?|binding-associated region:1-89 glutathione s tranferase tag:?-?|binding-associated region:170-310 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q86XJ1 uniprotkb:Q53HL2 intact:EBI-9248152|uniprotkb:B2RCN2|ensembl:ENSP00000266754|ensembl:ENSP00000439672|ensembl:ENSP00000448955 intact:EBI-979174|uniprotkb:Q53HN1|uniprotkb:Q96AM3|uniprotkb:Q9NVW5|ensembl:ENSP00000316121|ensembl:ENSP00000362146|intact:EBI-2557781|uniprotkb:D3DPT4 psi-mi:ga2l3_human(display_long)|uniprotkb:GAS2L3(gene name)|psi-mi:GAS2L3(display_short)|uniprotkb:Growth arrest-specific protein 2-like 3(gene name synonym) psi-mi:borea_human(display_long)|uniprotkb:Dasra-B(gene name synonym)|uniprotkb:Cell division cycle-associated protein 8(gene name synonym)|uniprotkb:Pluripotent embryonic stem cell-related gene 3 protein(gene name synonym)|uniprotkb:CDCA8(gene name)|psi-mi:CDCA8(display_short)|uniprotkb:PESCRG3(gene name synonym) psi-mi:"MI:0096"(pull down) Fackler et al. (2014) pubmed:24571573|imex:IM-22545 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9248247|imex:IM-22545-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290059.1|refseq:NP_777602.1|refseq:XP_005268861.1|refseq:XP_011536521.1|refseq:XP_011536522.1|refseq:XP_011536523.1|refseq:XP_016874695.1|ensembl:ENSG00000139354(gene)|ensembl:ENST00000266754(transcript)|ensembl:ENST00000539410(transcript)|ensembl:ENST00000547754(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR029932|interpro:IPR036534|interpro:IPR036872 rcsb pdb:6YIH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000327331(transcript)|ensembl:ENST00000373055(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0010369"(chromocenter)|go:"GO:0030496"(midbody)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|interpro:IPR018851|interpro:IPR018867|mint:Q53HL2|rcsb pdb:2KDD|rcsb pdb:2QFA|rcsb pdb:2RAW|ensembl:ENSG00000134690(gene)|rcsb pdb:2RAX|rcsb pdb:6YIE|rcsb pdb:6YIF|refseq:NP_001243804.1|refseq:NP_060571.1|dip:DIP-37995N - - - figure legend:f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/02/27 2014/10/16 rogid:faSiTYyhbHi2HBh52UIaeYm5kFA9606 rogid:LdL29UIjy+IvQfWTwvatWPabuq09606 intact-crc:AC44FBA45F3CD78C|rigid:dQwEdIzDKWS8EYgNTBaDYi8NRnY false glutathione s tranferase tag:?-?|binding-associated region:170-310 his tag:?-?|binding-associated region:142-280 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O95235 uniprotkb:Q86XJ1 intact:EBI-2551319|ensembl:ENSP00000378356|uniprotkb:B4DL79|uniprotkb:D3DQB6 intact:EBI-9248152|uniprotkb:B2RCN2|ensembl:ENSP00000266754|ensembl:ENSP00000439672|ensembl:ENSP00000448955 psi-mi:ki20a_human(display_long)|uniprotkb:RAB6KIFL(gene name synonym)|uniprotkb:Rabkinesin-6(gene name synonym)|uniprotkb:Rab6-interacting kinesin-like protein(gene name synonym)|uniprotkb:GG10_2(gene name synonym)|uniprotkb:KIF20A(gene name)|psi-mi:KIF20A(display_short)|uniprotkb:MKLP2(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 2(gene name synonym) psi-mi:ga2l3_human(display_long)|uniprotkb:GAS2L3(gene name)|psi-mi:GAS2L3(display_short)|uniprotkb:Growth arrest-specific protein 2-like 3(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fackler et al. (2014) pubmed:24571573|imex:IM-22545 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9248276|imex:IM-22545-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027326|interpro:IPR027417|interpro:IPR027640|rcsb pdb:6YIP|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|reactome:R-HSA-983189|ensembl:ENSG00000112984(gene)|ensembl:ENST00000394894(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0045171"(intercellular bridge)|go:"GO:0061952"(midbody abscission)|refseq:NP_005724.1 refseq:NP_001290059.1|refseq:NP_777602.1|refseq:XP_005268861.1|refseq:XP_011536521.1|refseq:XP_011536522.1|refseq:XP_011536523.1|refseq:XP_016874695.1|ensembl:ENSG00000139354(gene)|ensembl:ENST00000266754(transcript)|ensembl:ENST00000539410(transcript)|ensembl:ENST00000547754(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR029932|interpro:IPR036534|interpro:IPR036872 go:"GO:0030496"(midbody) - - figure legend:f6b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2014/02/27 2014/10/16 rogid:UEHYcHW3yyIJ98iv4jEC8+wd33M9606 rogid:faSiTYyhbHi2HBh52UIaeYm5kFA9606 intact-crc:6B0ABF113AD6AB73|rigid:WYUWc2HoRLosBDF5iL+oKV/AScM false - enhanced green fluorescent protein tag:?-?|binding-associated region:170-310 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9UBP0 uniprotkb:Q86XJ1 intact:EBI-1222832|uniprotkb:Q9UPR9|uniprotkb:A7E2A7|ensembl:ENSP00000320885 intact:EBI-9248152|uniprotkb:B2RCN2|ensembl:ENSP00000266754|ensembl:ENSP00000439672|ensembl:ENSP00000448955 psi-mi:spast_human(display_long)|uniprotkb:SPAST(gene name)|psi-mi:SPAST(display_short)|uniprotkb:KIAA1083(gene name synonym)|uniprotkb:SPG4(gene name synonym)|uniprotkb:ADPSP(gene name synonym)|uniprotkb:FSP2(gene name synonym)|uniprotkb:Spastic paraplegia 4 protein(gene name synonym) psi-mi:ga2l3_human(display_long)|uniprotkb:GAS2L3(gene name)|psi-mi:GAS2L3(display_short)|uniprotkb:Growth arrest-specific protein 2-like 3(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fackler et al. (2014) pubmed:24571573|imex:IM-22545 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9248304|imex:IM-22545-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055761.2|refseq:NP_955468.1|dip:DIP-38418N|ensembl:ENSG00000021574(gene)|ensembl:ENST00000315285(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008152"(metabolic process)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030496"(midbody)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032506"(cytokinetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051013"(microtubule severing)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|rcsb pdb:6PEN|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-9668328|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090148"(membrane fission)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR035106|interpro:IPR041569|rcsb pdb:3EAB|rcsb pdb:3VFD|rcsb pdb:5Z6Q|rcsb pdb:5Z6R|rcsb pdb:6PEK refseq:NP_001290059.1|refseq:NP_777602.1|refseq:XP_005268861.1|refseq:XP_011536521.1|refseq:XP_011536522.1|refseq:XP_011536523.1|refseq:XP_016874695.1|ensembl:ENSG00000139354(gene)|ensembl:ENST00000266754(transcript)|ensembl:ENST00000539410(transcript)|ensembl:ENST00000547754(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR029932|interpro:IPR036534|interpro:IPR036872 go:"GO:0030496"(midbody) - - figure legend:f7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2014/02/27 2014/10/16 rogid:E8b4FF6pWwyVd9teIInSCY4RzQE9606 rogid:faSiTYyhbHi2HBh52UIaeYm5kFA9606 intact-crc:66D55E026451F646|rigid:iU7xtML+H9Pqw3xl3k2TOu0SR6c false - enhanced green fluorescent protein tag:?-?|binding-associated region:170-310 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q86XJ1 uniprotkb:Q96GD4 intact:EBI-9248152|uniprotkb:B2RCN2|ensembl:ENSP00000266754|ensembl:ENSP00000439672|ensembl:ENSP00000448955 intact:EBI-624291|uniprotkb:O14630|uniprotkb:O60446|uniprotkb:O95083|uniprotkb:Q96DV5|uniprotkb:Q9UQ46|ensembl:ENSP00000463999|uniprotkb:B4DNM4|uniprotkb:D3DTR4|uniprotkb:C7G533|uniprotkb:C7G534|uniprotkb:C7G535|uniprotkb:J9JID1 psi-mi:ga2l3_human(display_long)|uniprotkb:GAS2L3(gene name)|psi-mi:GAS2L3(display_short)|uniprotkb:Growth arrest-specific protein 2-like 3(gene name synonym) psi-mi:aurkb_human(display_long)|uniprotkb:AIRK2(gene name synonym)|uniprotkb:Aurora- and IPL1-like midbody-associated protein 1(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 2(gene name synonym)|uniprotkb:STK-1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 5(gene name synonym)|uniprotkb:STK1(gene name synonym)|uniprotkb:STK5(gene name synonym)|uniprotkb:Aurora 1(gene name synonym)|uniprotkb:AURKB(gene name)|psi-mi:AURKB(display_short)|uniprotkb:AIK2(gene name synonym)|uniprotkb:AIM1(gene name synonym)|uniprotkb:ARK2(gene name synonym)|uniprotkb:STK12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-B(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fackler et al. (2014) pubmed:24571573|imex:IM-22545 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9248267|imex:IM-22545-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290059.1|refseq:NP_777602.1|refseq:XP_005268861.1|refseq:XP_011536521.1|refseq:XP_011536522.1|refseq:XP_011536523.1|refseq:XP_016874695.1|ensembl:ENSG00000139354(gene)|ensembl:ENST00000266754(transcript)|ensembl:ENST00000539410(transcript)|ensembl:ENST00000547754(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR029932|interpro:IPR036534|interpro:IPR036872 go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007568"(aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009838"(abscission)|go:"GO:0010369"(chromocenter)|go:"GO:0016570"(histone modification)|go:"GO:0019900"(kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0004674"(protein serine/threonine kinase activity)|ensembl:ENSG00000178999(gene)|ensembl:ENST00000585124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|refseq:NP_001271455.1|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1905116"(positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028772|interpro:IPR030616|mint:Q96GD4|rcsb pdb:4AF3|reactome:R-HSA-141444|reactome:R-HSA-174178|reactome:R-HSA-2467813|reactome:R-HSA-2500257|go:"GO:0051973"(positive regulation of telomerase activity)|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-6804756|reactome:R-HSA-68877|reactome:R-HSA-9022692|reactome:R-HSA-9648025|refseq:NP_004208.2|refseq:NP_001243763.1|refseq:NP_001300879.1|refseq:NP_001300880.1|refseq:NP_001300881.1|refseq:NP_001300882.1|refseq:NP_001300883.1|refseq:NP_001300884.1|refseq:XP_011522372.1|refseq:XP_011522374.1|refseq:XP_016880796.1|dip:DIP-34530N go:"GO:0030496"(midbody) - - figure legend:f6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2014/02/27 2014/10/16 rogid:faSiTYyhbHi2HBh52UIaeYm5kFA9606 rogid:4pmZhSoAp5JmH19k2tT+w3z9Hgo9606 intact-crc:647D5FD0FD7A89EC|rigid:6H3IbJxhpUhKdaq4GmWibKVHGLE false enhanced green fluorescent protein tag:?-?|binding-associated region:170-310 - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q96GD4 uniprotkb:Q9UBP0 intact:EBI-624291|uniprotkb:O14630|uniprotkb:O60446|uniprotkb:O95083|uniprotkb:Q96DV5|uniprotkb:Q9UQ46|ensembl:ENSP00000463999|uniprotkb:B4DNM4|uniprotkb:D3DTR4|uniprotkb:C7G533|uniprotkb:C7G534|uniprotkb:C7G535|uniprotkb:J9JID1 intact:EBI-1222832|uniprotkb:Q9UPR9|uniprotkb:A7E2A7|ensembl:ENSP00000320885 psi-mi:aurkb_human(display_long)|uniprotkb:AIRK2(gene name synonym)|uniprotkb:Aurora- and IPL1-like midbody-associated protein 1(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 2(gene name synonym)|uniprotkb:STK-1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 5(gene name synonym)|uniprotkb:STK1(gene name synonym)|uniprotkb:STK5(gene name synonym)|uniprotkb:Aurora 1(gene name synonym)|uniprotkb:AURKB(gene name)|psi-mi:AURKB(display_short)|uniprotkb:AIK2(gene name synonym)|uniprotkb:AIM1(gene name synonym)|uniprotkb:ARK2(gene name synonym)|uniprotkb:STK12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-B(gene name synonym) psi-mi:spast_human(display_long)|uniprotkb:SPAST(gene name)|psi-mi:SPAST(display_short)|uniprotkb:KIAA1083(gene name synonym)|uniprotkb:SPG4(gene name synonym)|uniprotkb:ADPSP(gene name synonym)|uniprotkb:FSP2(gene name synonym)|uniprotkb:Spastic paraplegia 4 protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fackler et al. (2014) pubmed:24571573|imex:IM-22545 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9248289|imex:IM-22545-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007568"(aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009838"(abscission)|go:"GO:0010369"(chromocenter)|go:"GO:0016570"(histone modification)|go:"GO:0019900"(kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0004674"(protein serine/threonine kinase activity)|ensembl:ENSG00000178999(gene)|ensembl:ENST00000585124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|refseq:NP_001271455.1|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1905116"(positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028772|interpro:IPR030616|mint:Q96GD4|rcsb pdb:4AF3|reactome:R-HSA-141444|reactome:R-HSA-174178|reactome:R-HSA-2467813|reactome:R-HSA-2500257|go:"GO:0051973"(positive regulation of telomerase activity)|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-6804756|reactome:R-HSA-68877|reactome:R-HSA-9022692|reactome:R-HSA-9648025|refseq:NP_004208.2|refseq:NP_001243763.1|refseq:NP_001300879.1|refseq:NP_001300880.1|refseq:NP_001300881.1|refseq:NP_001300882.1|refseq:NP_001300883.1|refseq:NP_001300884.1|refseq:XP_011522372.1|refseq:XP_011522374.1|refseq:XP_016880796.1|dip:DIP-34530N refseq:NP_055761.2|refseq:NP_955468.1|dip:DIP-38418N|ensembl:ENSG00000021574(gene)|ensembl:ENST00000315285(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008152"(metabolic process)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030496"(midbody)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032506"(cytokinetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051013"(microtubule severing)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|rcsb pdb:6PEN|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-9668328|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090148"(membrane fission)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR035106|interpro:IPR041569|rcsb pdb:3EAB|rcsb pdb:3VFD|rcsb pdb:5Z6Q|rcsb pdb:5Z6R|rcsb pdb:6PEK go:"GO:0030496"(midbody) - - figure legend:f7a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2014/02/27 2014/10/16 rogid:4pmZhSoAp5JmH19k2tT+w3z9Hgo9606 rogid:E8b4FF6pWwyVd9teIInSCY4RzQE9606 intact-crc:67C9774D2E63E25C|rigid:sv4whTPu8SLVjECCVppeN84h7Rs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)