#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UPT9 uniprotkb:Q13469 intact:EBI-723510|ensembl:ENSP00000261497|uniprotkb:A0JNS3|uniprotkb:Q2NLE2|uniprotkb:Q6MZY4|uniprotkb:Q8TBS8|uniprotkb:Q96IW5 intact:EBI-716258|uniprotkb:B5B2N9|uniprotkb:Q13468|uniprotkb:Q5TFW7|uniprotkb:Q5TFW8|uniprotkb:Q9NPX6|uniprotkb:Q9NQH3|uniprotkb:Q9UJR2|uniprotkb:B5B2P0|uniprotkb:B5B2N8|ensembl:ENSP00000379330|uniprotkb:B5B2P2|uniprotkb:B5B2P3 psi-mi:ubp22_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 22(gene name synonym)|uniprotkb:Deubiquitinating enzyme 22(gene name synonym)|uniprotkb:USP22(gene name)|psi-mi:USP22(display_short)|uniprotkb:KIAA1063(gene name synonym)|uniprotkb:USP3L(gene name synonym)|uniprotkb:Ubiquitin thioesterase 22(gene name synonym) psi-mi:nfac2_human(display_long)|uniprotkb:T-cell transcription factor NFAT1(gene name synonym)|uniprotkb:NFAT pre-existing subunit(gene name synonym)|uniprotkb:NFATC2(gene name)|psi-mi:NFATC2(display_short)|uniprotkb:NFAT1(gene name synonym)|uniprotkb:NFATP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gao et al. (2014) imex:IM-22233|pubmed:24561192 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9119882|imex:IM-22233-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056091.1|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|go:"GO:0007049"(cell cycle)|interpro:IPR028889|interpro:IPR038765|mint:Q9UPT9|go:"GO:0008270"(zinc ion binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|reactome:R-HSA-3214847|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|ensembl:ENSG00000124422(gene)|ensembl:ENST00000261497(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process) refseq:NP_001245221.1|refseq:NP_036472.2|refseq:NP_775114.1|refseq:NP_001245223.1|refseq:NP_001245225.1|refseq:NP_001129493.1|ensembl:ENSG00000101096(gene)|ensembl:ENST00000396009(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014904"(myotube cell development)|go:"GO:0016477"(cell migration)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0042493"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050853"(B cell receptor signaling pathway)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032397|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR037059|rcsb pdb:1A02|rcsb pdb:1OWR|rcsb pdb:1P7H|go:"GO:1990904"(ribonucleoprotein complex)|rcsb pdb:1PZU|rcsb pdb:1S9K|rcsb pdb:2AS5|rcsb pdb:2O93|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:3QRF|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-5607763|reactome:R-HSA-8877330|interpro:IPR008366("Nuclear factor of activated T cells (NFAT)")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|dip:DIP-27630N - - - figure legend:f2b f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/02/07 2014/10/16 rogid:8n1lOTC7I8dP3RY1IEUtIkJiSXc9606 rogid:SNvCfCooUb7MH1xO0prmM4jv+o49606 intact-crc:84B38E376978F1CE|rigid:+46Ne/BckGCz1fMCiHU2w2nPP44 false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UPT9 uniprotkb:Q13469 intact:EBI-723510|ensembl:ENSP00000261497|uniprotkb:A0JNS3|uniprotkb:Q2NLE2|uniprotkb:Q6MZY4|uniprotkb:Q8TBS8|uniprotkb:Q96IW5 intact:EBI-716258|uniprotkb:B5B2N9|uniprotkb:Q13468|uniprotkb:Q5TFW7|uniprotkb:Q5TFW8|uniprotkb:Q9NPX6|uniprotkb:Q9NQH3|uniprotkb:Q9UJR2|uniprotkb:B5B2P0|uniprotkb:B5B2N8|ensembl:ENSP00000379330|uniprotkb:B5B2P2|uniprotkb:B5B2P3 psi-mi:ubp22_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 22(gene name synonym)|uniprotkb:Deubiquitinating enzyme 22(gene name synonym)|uniprotkb:USP22(gene name)|psi-mi:USP22(display_short)|uniprotkb:KIAA1063(gene name synonym)|uniprotkb:USP3L(gene name synonym)|uniprotkb:Ubiquitin thioesterase 22(gene name synonym) psi-mi:nfac2_human(display_long)|uniprotkb:T-cell transcription factor NFAT1(gene name synonym)|uniprotkb:NFAT pre-existing subunit(gene name synonym)|uniprotkb:NFATC2(gene name)|psi-mi:NFATC2(display_short)|uniprotkb:NFAT1(gene name synonym)|uniprotkb:NFATP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gao et al. (2014) imex:IM-22233|pubmed:24561192 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9119872|imex:IM-22233-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056091.1|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|go:"GO:0007049"(cell cycle)|interpro:IPR028889|interpro:IPR038765|mint:Q9UPT9|go:"GO:0008270"(zinc ion binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|reactome:R-HSA-3214847|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|ensembl:ENSG00000124422(gene)|ensembl:ENST00000261497(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process) refseq:NP_001245221.1|refseq:NP_036472.2|refseq:NP_775114.1|refseq:NP_001245223.1|refseq:NP_001245225.1|refseq:NP_001129493.1|ensembl:ENSG00000101096(gene)|ensembl:ENST00000396009(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014904"(myotube cell development)|go:"GO:0016477"(cell migration)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0042493"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050853"(B cell receptor signaling pathway)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032397|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR037059|rcsb pdb:1A02|rcsb pdb:1OWR|rcsb pdb:1P7H|go:"GO:1990904"(ribonucleoprotein complex)|rcsb pdb:1PZU|rcsb pdb:1S9K|rcsb pdb:2AS5|rcsb pdb:2O93|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:3QRF|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-5607763|reactome:R-HSA-8877330|interpro:IPR008366("Nuclear factor of activated T cells (NFAT)")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|dip:DIP-27630N - - - figure legend:f2a f2c f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/02/07 2014/10/16 rogid:8n1lOTC7I8dP3RY1IEUtIkJiSXc9606 rogid:SNvCfCooUb7MH1xO0prmM4jv+o49606 intact-crc:B95A7F3D2E23B643|rigid:+46Ne/BckGCz1fMCiHU2w2nPP44 false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)