#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O75943	uniprotkb:O60934	intact:EBI-968231|ensembl:ENSP00000484854|ensembl:ENSP00000370151|ensembl:ENSP00000426191|ensembl:ENSP00000477962|ensembl:ENSP00000477996|ensembl:ENSP00000478167|ensembl:ENSP00000479160|ensembl:ENSP00000482371|uniprotkb:O75714|uniprotkb:Q7Z3S4|uniprotkb:Q9UNK7|uniprotkb:Q9UNR7|uniprotkb:Q9UNR8|uniprotkb:Q9UPF5|uniprotkb:A8K8X2|uniprotkb:D3DWA5	intact:EBI-494844|uniprotkb:O60672|uniprotkb:Q32NF7|uniprotkb:Q53FM6|uniprotkb:Q63HR6|uniprotkb:Q7LDM2|uniprotkb:B2R626|uniprotkb:B2RNC5|ensembl:ENSP00000265433	psi-mi:rad17_human(display_long)|uniprotkb:R24L(gene name synonym)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short)|uniprotkb:RF-C/activator 1 homolog(gene name synonym)	psi-mi:nbn_human(display_long)|uniprotkb:Nijmegen breakage syndrome protein 1(gene name synonym)|uniprotkb:Cell cycle regulatory protein p95(gene name synonym)|uniprotkb:NBN(gene name)|psi-mi:NBN(display_short)|uniprotkb:NBS1(gene name synonym)|uniprotkb:NBS(gene name synonym)|uniprotkb:P95(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2014)	imex:IM-23082|pubmed:24534091	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9550478|imex:IM-23082-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000380774(transcript)|ensembl:ENST00000509734(transcript)|ensembl:ENST00000610770(transcript)|ensembl:ENST00000611523(transcript)|ensembl:ENST00000612044(transcript)|ensembl:ENST00000616488(transcript)|ensembl:ENST00000616759(transcript)|ensembl:ENST00000620889(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003682"(chromatin binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042325"(regulation of phosphorylation)|ensembl:ENSG00000152942(gene)|ensembl:ENSG00000276618(gene)|reactome:R-HSA-69473|interpro:IPR004582(Checkpoint protein Rad24)|interpro:IPR018324|interpro:IPR027417|mint:O75943|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|refseq:NP_001265551.1|refseq:NP_002864.1|refseq:NP_579916.1|refseq:NP_579917.1|refseq:NP_579918.1|refseq:NP_579919.1|refseq:NP_579920.1|refseq:NP_579921.1|refseq:NP_579922.1|refseq:XP_016865168.1|refseq:XP_016865169.1|refseq:XP_016865170.1|dip:DIP-24254N|dip:DIP-34896N	refseq:NP_002476.2|refseq:NP_001019859.1|refseq:XP_011515347.1|dip:DIP-33605N|ensembl:ENSG00000104320(gene)|ensembl:ENST00000265433(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016605"(PML body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0045190"(isotype switching)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090656"(t-circle formation)|go:"GO:0090737"(telomere maintenance via telomere trimming)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013908(DNA  repair Nbs1, C-terminal)|interpro:IPR016592(Nibrin)|interpro:IPR032429|interpro:IPR036420|interpro:IPR040227|interpro:IPR043014|mint:O60934|rcsb pdb:5WQD|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616	-	-	-	figure legend:f2d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2014/06/16	2014/10/16	rogid:VFPeq06ilaDd09F/gQm6Dtvny2A9606	rogid:CTx61/3iHRb2kWfb5u/CSye5A2k9606	intact-crc:C53EEAD7DD87069E|rigid:hcYv7eAh8zF3HANe30JKRVeLzc4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O75943	uniprotkb:Q92878	intact:EBI-968231|ensembl:ENSP00000484854|ensembl:ENSP00000370151|ensembl:ENSP00000426191|ensembl:ENSP00000477962|ensembl:ENSP00000477996|ensembl:ENSP00000478167|ensembl:ENSP00000479160|ensembl:ENSP00000482371|uniprotkb:O75714|uniprotkb:Q7Z3S4|uniprotkb:Q9UNK7|uniprotkb:Q9UNR7|uniprotkb:Q9UNR8|uniprotkb:Q9UPF5|uniprotkb:A8K8X2|uniprotkb:D3DWA5	intact:EBI-495494|uniprotkb:O43254|uniprotkb:Q6GMT7|uniprotkb:Q6P5X3|uniprotkb:Q9UP86|uniprotkb:B9EGF5|ensembl:ENSP00000368100	psi-mi:rad17_human(display_long)|uniprotkb:R24L(gene name synonym)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short)|uniprotkb:RF-C/activator 1 homolog(gene name synonym)	psi-mi:rad50_human(display_long)|uniprotkb:RAD50(gene name)|psi-mi:RAD50(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2014)	imex:IM-23082|pubmed:24534091	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9550478|imex:IM-23082-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000380774(transcript)|ensembl:ENST00000509734(transcript)|ensembl:ENST00000610770(transcript)|ensembl:ENST00000611523(transcript)|ensembl:ENST00000612044(transcript)|ensembl:ENST00000616488(transcript)|ensembl:ENST00000616759(transcript)|ensembl:ENST00000620889(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003682"(chromatin binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042325"(regulation of phosphorylation)|ensembl:ENSG00000152942(gene)|ensembl:ENSG00000276618(gene)|reactome:R-HSA-69473|interpro:IPR004582(Checkpoint protein Rad24)|interpro:IPR018324|interpro:IPR027417|mint:O75943|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|refseq:NP_001265551.1|refseq:NP_002864.1|refseq:NP_579916.1|refseq:NP_579917.1|refseq:NP_579918.1|refseq:NP_579919.1|refseq:NP_579920.1|refseq:NP_579921.1|refseq:NP_579922.1|refseq:XP_016865168.1|refseq:XP_016865169.1|refseq:XP_016865170.1|dip:DIP-24254N|dip:DIP-34896N	refseq:NP_005723.2|dip:DIP-33606N|ensembl:ENSG00000113522(gene)|ensembl:ENST00000378823(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR013134(Zinc hook, Rad50)|interpro:IPR027417|interpro:IPR038729|mint:Q92878|rcsb pdb:5GOX|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR004584(Recombination/repair protein Rad50)	-	-	-	figure legend:f2d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2014/06/16	2014/10/16	rogid:VFPeq06ilaDd09F/gQm6Dtvny2A9606	rogid:yZsT5GcpA9HeFMoK4Jb1HYhrdKQ9606	intact-crc:C53EEAD7DD87069E|rigid:hcYv7eAh8zF3HANe30JKRVeLzc4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O75943	uniprotkb:P49959	intact:EBI-968231|ensembl:ENSP00000484854|ensembl:ENSP00000370151|ensembl:ENSP00000426191|ensembl:ENSP00000477962|ensembl:ENSP00000477996|ensembl:ENSP00000478167|ensembl:ENSP00000479160|ensembl:ENSP00000482371|uniprotkb:O75714|uniprotkb:Q7Z3S4|uniprotkb:Q9UNK7|uniprotkb:Q9UNR7|uniprotkb:Q9UNR8|uniprotkb:Q9UPF5|uniprotkb:A8K8X2|uniprotkb:D3DWA5	intact:EBI-396513|uniprotkb:O43475|uniprotkb:B3KTC7|ensembl:ENSP00000325863	psi-mi:rad17_human(display_long)|uniprotkb:R24L(gene name synonym)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short)|uniprotkb:RF-C/activator 1 homolog(gene name synonym)	psi-mi:mre11_human(display_long)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)|uniprotkb:Double-strand break repair protein MRE11A(gene name synonym)|uniprotkb:HNGS1(gene name synonym)|uniprotkb:MRE11A(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog 1(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2014)	imex:IM-23082|pubmed:24534091	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9550478|imex:IM-23082-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000380774(transcript)|ensembl:ENST00000509734(transcript)|ensembl:ENST00000610770(transcript)|ensembl:ENST00000611523(transcript)|ensembl:ENST00000612044(transcript)|ensembl:ENST00000616488(transcript)|ensembl:ENST00000616759(transcript)|ensembl:ENST00000620889(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003682"(chromatin binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042325"(regulation of phosphorylation)|ensembl:ENSG00000152942(gene)|ensembl:ENSG00000276618(gene)|reactome:R-HSA-69473|interpro:IPR004582(Checkpoint protein Rad24)|interpro:IPR018324|interpro:IPR027417|mint:O75943|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|refseq:NP_001265551.1|refseq:NP_002864.1|refseq:NP_579916.1|refseq:NP_579917.1|refseq:NP_579918.1|refseq:NP_579919.1|refseq:NP_579920.1|refseq:NP_579921.1|refseq:NP_579922.1|refseq:XP_016865168.1|refseq:XP_016865169.1|refseq:XP_016865170.1|dip:DIP-24254N|dip:DIP-34896N	refseq:NP_005581.2|refseq:NP_005582.1|refseq:XP_011541139.1|refseq:XP_016873261.1|dip:DIP-33238N|ensembl:ENSG00000020922(gene)|ensembl:ENST00000323929(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|mint:P49959|rcsb pdb:3T1I|reactome:R-HSA-1834949|reactome:R-HSA-2559586|reactome:R-HSA-3270619|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446	-	-	-	figure legend:f2d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2014/06/16	2014/10/16	rogid:VFPeq06ilaDd09F/gQm6Dtvny2A9606	rogid:fgwgA0BcNZ9phGBaOSYjkldDgeI9606	intact-crc:C53EEAD7DD87069E|rigid:hcYv7eAh8zF3HANe30JKRVeLzc4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60934	uniprotkb:O75943	intact:EBI-494844|uniprotkb:O60672|uniprotkb:Q32NF7|uniprotkb:Q53FM6|uniprotkb:Q63HR6|uniprotkb:Q7LDM2|uniprotkb:B2R626|uniprotkb:B2RNC5|ensembl:ENSP00000265433	intact:EBI-968231|ensembl:ENSP00000484854|ensembl:ENSP00000370151|ensembl:ENSP00000426191|ensembl:ENSP00000477962|ensembl:ENSP00000477996|ensembl:ENSP00000478167|ensembl:ENSP00000479160|ensembl:ENSP00000482371|uniprotkb:O75714|uniprotkb:Q7Z3S4|uniprotkb:Q9UNK7|uniprotkb:Q9UNR7|uniprotkb:Q9UNR8|uniprotkb:Q9UPF5|uniprotkb:A8K8X2|uniprotkb:D3DWA5	psi-mi:nbn_human(display_long)|uniprotkb:Nijmegen breakage syndrome protein 1(gene name synonym)|uniprotkb:Cell cycle regulatory protein p95(gene name synonym)|uniprotkb:NBN(gene name)|psi-mi:NBN(display_short)|uniprotkb:NBS1(gene name synonym)|uniprotkb:NBS(gene name synonym)|uniprotkb:P95(gene name synonym)	psi-mi:rad17_human(display_long)|uniprotkb:R24L(gene name synonym)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short)|uniprotkb:RF-C/activator 1 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2014)	imex:IM-23082|pubmed:24534091	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9550451|imex:IM-23082-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002476.2|refseq:NP_001019859.1|refseq:XP_011515347.1|dip:DIP-33605N|ensembl:ENSG00000104320(gene)|ensembl:ENST00000265433(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016605"(PML body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0045190"(isotype switching)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090656"(t-circle formation)|go:"GO:0090737"(telomere maintenance via telomere trimming)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013908(DNA  repair Nbs1, C-terminal)|interpro:IPR016592(Nibrin)|interpro:IPR032429|interpro:IPR036420|interpro:IPR040227|interpro:IPR043014|mint:O60934|rcsb pdb:5WQD|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616	ensembl:ENST00000380774(transcript)|ensembl:ENST00000509734(transcript)|ensembl:ENST00000610770(transcript)|ensembl:ENST00000611523(transcript)|ensembl:ENST00000612044(transcript)|ensembl:ENST00000616488(transcript)|ensembl:ENST00000616759(transcript)|ensembl:ENST00000620889(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003682"(chromatin binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042325"(regulation of phosphorylation)|ensembl:ENSG00000152942(gene)|ensembl:ENSG00000276618(gene)|reactome:R-HSA-69473|interpro:IPR004582(Checkpoint protein Rad24)|interpro:IPR018324|interpro:IPR027417|mint:O75943|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|refseq:NP_001265551.1|refseq:NP_002864.1|refseq:NP_579916.1|refseq:NP_579917.1|refseq:NP_579918.1|refseq:NP_579919.1|refseq:NP_579920.1|refseq:NP_579921.1|refseq:NP_579922.1|refseq:XP_016865168.1|refseq:XP_016865169.1|refseq:XP_016865170.1|dip:DIP-24254N|dip:DIP-34896N	-	-	-	figure legend:f2a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2014/06/16	2014/10/16	rogid:CTx61/3iHRb2kWfb5u/CSye5A2k9606	rogid:VFPeq06ilaDd09F/gQm6Dtvny2A9606	intact-crc:2349358760F09AC3|rigid:wl4v9Rp49ZruUWaqm9r3dnCNKec	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49959	uniprotkb:O75943	intact:EBI-396513|uniprotkb:O43475|uniprotkb:B3KTC7|ensembl:ENSP00000325863	intact:EBI-968231|ensembl:ENSP00000484854|ensembl:ENSP00000370151|ensembl:ENSP00000426191|ensembl:ENSP00000477962|ensembl:ENSP00000477996|ensembl:ENSP00000478167|ensembl:ENSP00000479160|ensembl:ENSP00000482371|uniprotkb:O75714|uniprotkb:Q7Z3S4|uniprotkb:Q9UNK7|uniprotkb:Q9UNR7|uniprotkb:Q9UNR8|uniprotkb:Q9UPF5|uniprotkb:A8K8X2|uniprotkb:D3DWA5	psi-mi:mre11_human(display_long)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)|uniprotkb:Double-strand break repair protein MRE11A(gene name synonym)|uniprotkb:HNGS1(gene name synonym)|uniprotkb:MRE11A(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog 1(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog A(gene name synonym)	psi-mi:rad17_human(display_long)|uniprotkb:R24L(gene name synonym)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short)|uniprotkb:RF-C/activator 1 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2014)	imex:IM-23082|pubmed:24534091	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9550455|imex:IM-23082-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005581.2|refseq:NP_005582.1|refseq:XP_011541139.1|refseq:XP_016873261.1|dip:DIP-33238N|ensembl:ENSG00000020922(gene)|ensembl:ENST00000323929(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|mint:P49959|rcsb pdb:3T1I|reactome:R-HSA-1834949|reactome:R-HSA-2559586|reactome:R-HSA-3270619|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446	ensembl:ENST00000380774(transcript)|ensembl:ENST00000509734(transcript)|ensembl:ENST00000610770(transcript)|ensembl:ENST00000611523(transcript)|ensembl:ENST00000612044(transcript)|ensembl:ENST00000616488(transcript)|ensembl:ENST00000616759(transcript)|ensembl:ENST00000620889(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003682"(chromatin binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042325"(regulation of phosphorylation)|ensembl:ENSG00000152942(gene)|ensembl:ENSG00000276618(gene)|reactome:R-HSA-69473|interpro:IPR004582(Checkpoint protein Rad24)|interpro:IPR018324|interpro:IPR027417|mint:O75943|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|refseq:NP_001265551.1|refseq:NP_002864.1|refseq:NP_579916.1|refseq:NP_579917.1|refseq:NP_579918.1|refseq:NP_579919.1|refseq:NP_579920.1|refseq:NP_579921.1|refseq:NP_579922.1|refseq:XP_016865168.1|refseq:XP_016865169.1|refseq:XP_016865170.1|dip:DIP-24254N|dip:DIP-34896N	-	-	-	figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2014/06/16	2014/10/16	rogid:fgwgA0BcNZ9phGBaOSYjkldDgeI9606	rogid:VFPeq06ilaDd09F/gQm6Dtvny2A9606	intact-crc:234BE58760F09AC3|rigid:9QGjO1POq1LQDbpHiLDexXfPYpk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92878	uniprotkb:O75943	intact:EBI-495494|uniprotkb:O43254|uniprotkb:Q6GMT7|uniprotkb:Q6P5X3|uniprotkb:Q9UP86|uniprotkb:B9EGF5|ensembl:ENSP00000368100	intact:EBI-968231|ensembl:ENSP00000484854|ensembl:ENSP00000370151|ensembl:ENSP00000426191|ensembl:ENSP00000477962|ensembl:ENSP00000477996|ensembl:ENSP00000478167|ensembl:ENSP00000479160|ensembl:ENSP00000482371|uniprotkb:O75714|uniprotkb:Q7Z3S4|uniprotkb:Q9UNK7|uniprotkb:Q9UNR7|uniprotkb:Q9UNR8|uniprotkb:Q9UPF5|uniprotkb:A8K8X2|uniprotkb:D3DWA5	psi-mi:rad50_human(display_long)|uniprotkb:RAD50(gene name)|psi-mi:RAD50(display_short)	psi-mi:rad17_human(display_long)|uniprotkb:R24L(gene name synonym)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short)|uniprotkb:RF-C/activator 1 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2014)	imex:IM-23082|pubmed:24534091	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9550472|imex:IM-23082-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005723.2|dip:DIP-33606N|ensembl:ENSG00000113522(gene)|ensembl:ENST00000378823(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR013134(Zinc hook, Rad50)|interpro:IPR027417|interpro:IPR038729|mint:Q92878|rcsb pdb:5GOX|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR004584(Recombination/repair protein Rad50)	ensembl:ENST00000380774(transcript)|ensembl:ENST00000509734(transcript)|ensembl:ENST00000610770(transcript)|ensembl:ENST00000611523(transcript)|ensembl:ENST00000612044(transcript)|ensembl:ENST00000616488(transcript)|ensembl:ENST00000616759(transcript)|ensembl:ENST00000620889(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003682"(chromatin binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042325"(regulation of phosphorylation)|ensembl:ENSG00000152942(gene)|ensembl:ENSG00000276618(gene)|reactome:R-HSA-69473|interpro:IPR004582(Checkpoint protein Rad24)|interpro:IPR018324|interpro:IPR027417|mint:O75943|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|refseq:NP_001265551.1|refseq:NP_002864.1|refseq:NP_579916.1|refseq:NP_579917.1|refseq:NP_579918.1|refseq:NP_579919.1|refseq:NP_579920.1|refseq:NP_579921.1|refseq:NP_579922.1|refseq:XP_016865168.1|refseq:XP_016865169.1|refseq:XP_016865170.1|dip:DIP-24254N|dip:DIP-34896N	-	-	-	figure legend:f2c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2014/06/16	2014/10/16	rogid:yZsT5GcpA9HeFMoK4Jb1HYhrdKQ9606	rogid:VFPeq06ilaDd09F/gQm6Dtvny2A9606	intact-crc:8EDC05E0966C01EC|rigid:TLxtBGAw5MuAMxXYhUJOQiqV2EU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60934	uniprotkb:O75943	intact:EBI-494844|uniprotkb:O60672|uniprotkb:Q32NF7|uniprotkb:Q53FM6|uniprotkb:Q63HR6|uniprotkb:Q7LDM2|uniprotkb:B2R626|uniprotkb:B2RNC5|ensembl:ENSP00000265433	intact:EBI-968231|ensembl:ENSP00000484854|ensembl:ENSP00000370151|ensembl:ENSP00000426191|ensembl:ENSP00000477962|ensembl:ENSP00000477996|ensembl:ENSP00000478167|ensembl:ENSP00000479160|ensembl:ENSP00000482371|uniprotkb:O75714|uniprotkb:Q7Z3S4|uniprotkb:Q9UNK7|uniprotkb:Q9UNR7|uniprotkb:Q9UNR8|uniprotkb:Q9UPF5|uniprotkb:A8K8X2|uniprotkb:D3DWA5	psi-mi:nbn_human(display_long)|uniprotkb:Nijmegen breakage syndrome protein 1(gene name synonym)|uniprotkb:Cell cycle regulatory protein p95(gene name synonym)|uniprotkb:NBN(gene name)|psi-mi:NBN(display_short)|uniprotkb:NBS1(gene name synonym)|uniprotkb:NBS(gene name synonym)|uniprotkb:P95(gene name synonym)	psi-mi:rad17_human(display_long)|uniprotkb:R24L(gene name synonym)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short)|uniprotkb:RF-C/activator 1 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wang et al. (2014)	imex:IM-23082|pubmed:24534091	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9550492|imex:IM-23082-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002476.2|refseq:NP_001019859.1|refseq:XP_011515347.1|dip:DIP-33605N|ensembl:ENSG00000104320(gene)|ensembl:ENST00000265433(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016605"(PML body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0045190"(isotype switching)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090656"(t-circle formation)|go:"GO:0090737"(telomere maintenance via telomere trimming)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013908(DNA  repair Nbs1, C-terminal)|interpro:IPR016592(Nibrin)|interpro:IPR032429|interpro:IPR036420|interpro:IPR040227|interpro:IPR043014|mint:O60934|rcsb pdb:5WQD|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616	ensembl:ENST00000380774(transcript)|ensembl:ENST00000509734(transcript)|ensembl:ENST00000610770(transcript)|ensembl:ENST00000611523(transcript)|ensembl:ENST00000612044(transcript)|ensembl:ENST00000616488(transcript)|ensembl:ENST00000616759(transcript)|ensembl:ENST00000620889(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003682"(chromatin binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042325"(regulation of phosphorylation)|ensembl:ENSG00000152942(gene)|ensembl:ENSG00000276618(gene)|reactome:R-HSA-69473|interpro:IPR004582(Checkpoint protein Rad24)|interpro:IPR018324|interpro:IPR027417|mint:O75943|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|refseq:NP_001265551.1|refseq:NP_002864.1|refseq:NP_579916.1|refseq:NP_579917.1|refseq:NP_579918.1|refseq:NP_579919.1|refseq:NP_579920.1|refseq:NP_579921.1|refseq:NP_579922.1|refseq:XP_016865168.1|refseq:XP_016865169.1|refseq:XP_016865170.1|dip:DIP-24254N|dip:DIP-34896N	-	-	-	figure legend:f2f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/16	2014/10/16	rogid:CTx61/3iHRb2kWfb5u/CSye5A2k9606	rogid:VFPeq06ilaDd09F/gQm6Dtvny2A9606	intact-crc:F8E53CF9965149DC|rigid:wl4v9Rp49ZruUWaqm9r3dnCNKec	false	binding-associated region:24-100|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60934	uniprotkb:O75943	intact:EBI-494844|uniprotkb:O60672|uniprotkb:Q32NF7|uniprotkb:Q53FM6|uniprotkb:Q63HR6|uniprotkb:Q7LDM2|uniprotkb:B2R626|uniprotkb:B2RNC5|ensembl:ENSP00000265433	intact:EBI-968231|ensembl:ENSP00000484854|ensembl:ENSP00000370151|ensembl:ENSP00000426191|ensembl:ENSP00000477962|ensembl:ENSP00000477996|ensembl:ENSP00000478167|ensembl:ENSP00000479160|ensembl:ENSP00000482371|uniprotkb:O75714|uniprotkb:Q7Z3S4|uniprotkb:Q9UNK7|uniprotkb:Q9UNR7|uniprotkb:Q9UNR8|uniprotkb:Q9UPF5|uniprotkb:A8K8X2|uniprotkb:D3DWA5	psi-mi:nbn_human(display_long)|uniprotkb:Nijmegen breakage syndrome protein 1(gene name synonym)|uniprotkb:Cell cycle regulatory protein p95(gene name synonym)|uniprotkb:NBN(gene name)|psi-mi:NBN(display_short)|uniprotkb:NBS1(gene name synonym)|uniprotkb:NBS(gene name synonym)|uniprotkb:P95(gene name synonym)	psi-mi:rad17_human(display_long)|uniprotkb:R24L(gene name synonym)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short)|uniprotkb:RF-C/activator 1 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wang et al. (2014)	imex:IM-23082|pubmed:24534091	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9550484|imex:IM-23082-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002476.2|refseq:NP_001019859.1|refseq:XP_011515347.1|dip:DIP-33605N|ensembl:ENSG00000104320(gene)|ensembl:ENST00000265433(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016605"(PML body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0045190"(isotype switching)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090656"(t-circle formation)|go:"GO:0090737"(telomere maintenance via telomere trimming)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013908(DNA  repair Nbs1, C-terminal)|interpro:IPR016592(Nibrin)|interpro:IPR032429|interpro:IPR036420|interpro:IPR040227|interpro:IPR043014|mint:O60934|rcsb pdb:5WQD|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616	ensembl:ENST00000380774(transcript)|ensembl:ENST00000509734(transcript)|ensembl:ENST00000610770(transcript)|ensembl:ENST00000611523(transcript)|ensembl:ENST00000612044(transcript)|ensembl:ENST00000616488(transcript)|ensembl:ENST00000616759(transcript)|ensembl:ENST00000620889(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003682"(chromatin binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042325"(regulation of phosphorylation)|ensembl:ENSG00000152942(gene)|ensembl:ENSG00000276618(gene)|reactome:R-HSA-69473|interpro:IPR004582(Checkpoint protein Rad24)|interpro:IPR018324|interpro:IPR027417|mint:O75943|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|refseq:NP_001265551.1|refseq:NP_002864.1|refseq:NP_579916.1|refseq:NP_579917.1|refseq:NP_579918.1|refseq:NP_579919.1|refseq:NP_579920.1|refseq:NP_579921.1|refseq:NP_579922.1|refseq:XP_016865168.1|refseq:XP_016865169.1|refseq:XP_016865170.1|dip:DIP-24254N|dip:DIP-34896N	-	-	-	figure legend:f2e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/16	2014/10/16	rogid:CTx61/3iHRb2kWfb5u/CSye5A2k9606	rogid:VFPeq06ilaDd09F/gQm6Dtvny2A9606	intact-crc:75141F803782917B|rigid:wl4v9Rp49ZruUWaqm9r3dnCNKec	false	-	glutathione s tranferase tag:?-?|binding-associated region:570-670	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:O60934	uniprotkb:O75943	intact:EBI-494844|uniprotkb:O60672|uniprotkb:Q32NF7|uniprotkb:Q53FM6|uniprotkb:Q63HR6|uniprotkb:Q7LDM2|uniprotkb:B2R626|uniprotkb:B2RNC5|ensembl:ENSP00000265433	intact:EBI-968231|ensembl:ENSP00000484854|ensembl:ENSP00000370151|ensembl:ENSP00000426191|ensembl:ENSP00000477962|ensembl:ENSP00000477996|ensembl:ENSP00000478167|ensembl:ENSP00000479160|ensembl:ENSP00000482371|uniprotkb:O75714|uniprotkb:Q7Z3S4|uniprotkb:Q9UNK7|uniprotkb:Q9UNR7|uniprotkb:Q9UNR8|uniprotkb:Q9UPF5|uniprotkb:A8K8X2|uniprotkb:D3DWA5	psi-mi:nbn_human(display_long)|uniprotkb:Nijmegen breakage syndrome protein 1(gene name synonym)|uniprotkb:Cell cycle regulatory protein p95(gene name synonym)|uniprotkb:NBN(gene name)|psi-mi:NBN(display_short)|uniprotkb:NBS1(gene name synonym)|uniprotkb:NBS(gene name synonym)|uniprotkb:P95(gene name synonym)	psi-mi:rad17_human(display_long)|uniprotkb:R24L(gene name synonym)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short)|uniprotkb:RF-C/activator 1 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wang et al. (2014)	imex:IM-23082|pubmed:24534091	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9550529|imex:IM-23082-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002476.2|refseq:NP_001019859.1|refseq:XP_011515347.1|dip:DIP-33605N|ensembl:ENSG00000104320(gene)|ensembl:ENST00000265433(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016605"(PML body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0045190"(isotype switching)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090656"(t-circle formation)|go:"GO:0090737"(telomere maintenance via telomere trimming)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013908(DNA  repair Nbs1, C-terminal)|interpro:IPR016592(Nibrin)|interpro:IPR032429|interpro:IPR036420|interpro:IPR040227|interpro:IPR043014|mint:O60934|rcsb pdb:5WQD|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616	ensembl:ENST00000380774(transcript)|ensembl:ENST00000509734(transcript)|ensembl:ENST00000610770(transcript)|ensembl:ENST00000611523(transcript)|ensembl:ENST00000612044(transcript)|ensembl:ENST00000616488(transcript)|ensembl:ENST00000616759(transcript)|ensembl:ENST00000620889(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003682"(chromatin binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042325"(regulation of phosphorylation)|ensembl:ENSG00000152942(gene)|ensembl:ENSG00000276618(gene)|reactome:R-HSA-69473|interpro:IPR004582(Checkpoint protein Rad24)|interpro:IPR018324|interpro:IPR027417|mint:O75943|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|refseq:NP_001265551.1|refseq:NP_002864.1|refseq:NP_579916.1|refseq:NP_579917.1|refseq:NP_579918.1|refseq:NP_579919.1|refseq:NP_579920.1|refseq:NP_579921.1|refseq:NP_579922.1|refseq:XP_016865168.1|refseq:XP_016865169.1|refseq:XP_016865170.1|dip:DIP-24254N|dip:DIP-34896N	-	-	-	figure legend:f7a|comment:o test this, we synthe- sized biotinylated phospho-T622 Rad17 peptide and control unphos- phorylated peptide with the identical sequence. As shown in Fig 7A, a phospho-T622 Rad17 peptide is able to pull down the FHA domain of NBS1, but not the C-terminal region, with a higher efficiency than the non-phospho-T622 Rad17 peptide, indicating that Thr622 phos- phorylation is directly involved in Rad17-NBS1 interaction. I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/16	2014/10/16	rogid:CTx61/3iHRb2kWfb5u/CSye5A2k9606	rogid:VFPeq06ilaDd09F/gQm6Dtvny2A9606	intact-crc:D2D7FF91F65C8E7F|rigid:wl4v9Rp49ZruUWaqm9r3dnCNKec	false	binding-associated region:24-100|glutathione s tranferase tag:?-?	phosphorylated residue:633-633|binding-associated region:627-638	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0083"(peptide synthesis)