#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P04689 uniprotkb:O94452 intact:EBI-1148821|uniprotkb:Q9HGL7|ensemblfungi:"SPBC800.05c.1:pep" intact:EBI-9099862|ensemblfungi:"SPAC1687.10.1:pep" psi-mi:tba2_schpo(display_long)|uniprotkb:tub1(gene name)|psi-mi:tub1(display_short)|uniprotkb:alp2(gene name synonym)|uniprotkb:atb2(gene name synonym)|uniprotkb:SPBC800.05c(orf name) psi-mi:mcp1_schpo(display_long)|uniprotkb:mcp1(gene name)|psi-mi:mcp1(display_short)|uniprotkb:SPAC1687.10(orf name) psi-mi:"MI:0663"(confocal microscopy) Zheng et al. (2014) imex:IM-22210|pubmed:24530531 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9099858|imex:IM-22210-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_595106.1|interpro:IPR002452(Alpha tubulin)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0098863"(nuclear migration by microtubule mediated pushing forces)|go:"GO:0007052"(mitotic spindle organization)|ensemblfungi:SPBC800.05c(gene)|ensemblfungi:SPBC800.05c.1(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000280"(nuclear division)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-SPO-114608 refseq:NP_593128.1|interpro:IPR007145(MAP65/ASE1)|ensemblfungi:SPAC1687.10(gene)|ensemblfungi:SPAC1687.10.1(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990023"(mitotic spindle midzone) go:"GO:0005874"(microtubule) - - figure legend:f1b|comment:"In our microscopy screen for new MAPs, we found that mcp1p displayed remarkable staining along 3 cytoplasmic microtubules when overexpressed from the inducible nmt promoter in vegetative cells (Fig. 1B). This microtubule localization is consistent with the result from the ORFeome localization project [20]. In addition, we noted that overexpressed mcp1p appeared to concentrate near microtubule plus ends, adjacent to cell tips. Consistent with this, the endogenous mcp1p tagged with three tandem GFPs at its carboxyl-terminus (mcp1p-3GFP) mainly resided at a microtubule region near cell tips, likely at microtubule plus ends (Fig 1C). These findings suggest that mcp1p is also a MAP in vegetative cells."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2014/01/28 2014/10/16 rogid:lekKgowtqaYQSjiTQyiH4cbM6Ok284812 rogid:MVfg1zD+eKyJoJ1I8e6ERWjtXeU284812 intact-crc:E26F199A54D4E91D|rigid:OF5z4rEopdkfpUEpeAJvK/7aDzU false mcherry fluorescent protein tag:?-? yellow fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P04689 uniprotkb:O94452 intact:EBI-1148821|uniprotkb:Q9HGL7|ensemblfungi:"SPBC800.05c.1:pep" intact:EBI-9099862|ensemblfungi:"SPAC1687.10.1:pep" psi-mi:tba2_schpo(display_long)|uniprotkb:tub1(gene name)|psi-mi:tub1(display_short)|uniprotkb:alp2(gene name synonym)|uniprotkb:atb2(gene name synonym)|uniprotkb:SPBC800.05c(orf name) psi-mi:mcp1_schpo(display_long)|uniprotkb:mcp1(gene name)|psi-mi:mcp1(display_short)|uniprotkb:SPAC1687.10(orf name) psi-mi:"MI:0663"(confocal microscopy) Zheng et al. (2014) imex:IM-22210|pubmed:24530531 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9099904|imex:IM-22210-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_595106.1|interpro:IPR002452(Alpha tubulin)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0098863"(nuclear migration by microtubule mediated pushing forces)|go:"GO:0007052"(mitotic spindle organization)|ensemblfungi:SPBC800.05c(gene)|ensemblfungi:SPBC800.05c.1(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000280"(nuclear division)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-SPO-114608 refseq:NP_593128.1|interpro:IPR007145(MAP65/ASE1)|ensemblfungi:SPAC1687.10(gene)|ensemblfungi:SPAC1687.10.1(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990023"(mitotic spindle midzone) go:"GO:0005874"(microtubule) - - figure legend:f1c f3b sf2b|comment:"In our microscopy screen for new MAPs, we found that mcp1p displayed remarkable staining along 3 cytoplasmic microtubules when overexpressed from the inducible nmt promoter in vegetative cells (Fig. 1B). This microtubule localization is consistent with the result from the ORFeome localization project [20]. In addition, we noted that overexpressed mcp1p appeared to concentrate near microtubule plus ends, adjacent to cell tips. Consistent with this, the endogenous mcp1p tagged with three tandem GFPs at its carboxyl-terminus (mcp1p-3GFP) mainly resided at a microtubule region near cell tips, likely at microtubule plus ends (Fig 1C). These findings suggest that mcp1p is also a MAP in vegetative cells."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2014/01/28 2014/10/16 rogid:lekKgowtqaYQSjiTQyiH4cbM6Ok284812 rogid:MVfg1zD+eKyJoJ1I8e6ERWjtXeU284812 intact-crc:98DCF4E6A99B6EF3|rigid:OF5z4rEopdkfpUEpeAJvK/7aDzU false mcherry fluorescent protein tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q10113 uniprotkb:O94452 intact:EBI-1002268|ensemblfungi:"SPAC18G6.15.1:pep" intact:EBI-9099862|ensemblfungi:"SPAC1687.10.1:pep" psi-mi:mal3_schpo(display_long)|uniprotkb:mal3(gene name)|psi-mi:mal3(display_short)|uniprotkb:SPAC18G6.15(orf name) psi-mi:mcp1_schpo(display_long)|uniprotkb:mcp1(gene name)|psi-mi:mcp1(display_short)|uniprotkb:SPAC1687.10(orf name) psi-mi:"MI:0663"(confocal microscopy) Zheng et al. (2014) imex:IM-22210|pubmed:24530531 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9099932|imex:IM-22210-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593678.1|ensemblfungi:SPAC18G6.15.1(transcript)|go:"GO:0000235"(astral microtubule)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030989"(dynein-driven meiotic oscillatory nuclear movement)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0055028"(cortical microtubule)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0099609"(microtubule lateral binding)|ensemblfungi:SPAC18G6.15(gene)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR036133|interpro:IPR036872|rcsb pdb:4ABO|rcsb pdb:5M97|rcsb pdb:5M9E|rcsb pdb:5MJS|dip:DIP-35342N refseq:NP_593128.1|interpro:IPR007145(MAP65/ASE1)|ensemblfungi:SPAC1687.10(gene)|ensemblfungi:SPAC1687.10.1(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990023"(mitotic spindle midzone) go:"GO:0005874"(microtubule) crc64:9527D31CAA024256 - figure legend:f1c f3b sf2b|comment:"In our microscopy screen for new MAPs, we found that mcp1p displayed remarkable staining along 3 cytoplasmic microtubules when overexpressed from the inducible nmt promoter in vegetative cells (Fig. 1B). This microtubule localization is consistent with the result from the ORFeome localization project [20]. In addition, we noted that overexpressed mcp1p appeared to concentrate near microtubule plus ends, adjacent to cell tips. Consistent with this, the endogenous mcp1p tagged with three tandem GFPs at its carboxyl-terminus (mcp1p-3GFP) mainly resided at a microtubule region near cell tips, likely at microtubule plus ends (Fig 1C). These findings suggest that mcp1p is also a MAP in vegetative cells."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2014/01/28 2014/10/16 rogid:AX1qyn1e4krMTVjlDLaZE339exo284812 rogid:MVfg1zD+eKyJoJ1I8e6ERWjtXeU284812 intact-crc:C419728BAAB02393|rigid:9qdPL20RRIFEPf7wwwmtZOkLVfM false mcherry fluorescent protein tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)