#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:C1L335	uniprotkb:C1L335	intact:EBI-9107991	intact:EBI-9107991	psi-mi:c1l335_sorma(display_long)|uniprotkb:cas1(gene name)|psi-mi:cas1(display_short)|uniprotkb:Carbonate dehydratase(gene name synonym)	psi-mi:c1l335_sorma(display_long)|uniprotkb:cas1(gene name)|psi-mi:cas1(display_short)|uniprotkb:Carbonate dehydratase(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Lehneck et al. (2014)	pubmed:24506675|imex:IM-22214	taxid:5147(sorma)|taxid:5147(Sordaria macrospora)	taxid:5147(sorma)|taxid:5147(Sordaria macrospora)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9107986|imex:IM-22214-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001765(Carbonic anhydrase)|interpro:IPR015892(Carbonic anhydrase, prokaryotic-like, conserved site)|interpro:IPR036874|go:"GO:0004089"(carbonate dehydratase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015976"(carbon utilization)	interpro:IPR001765(Carbonic anhydrase)|interpro:IPR015892(Carbonic anhydrase, prokaryotic-like, conserved site)|interpro:IPR036874|go:"GO:0004089"(carbonate dehydratase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015976"(carbon utilization)	rcsb pdb:4o1j	-	-	figure legend:t3|comment:"CAS1 crystallized in space group  P212121 with two monomers occupying the asymmetric unit. The structure was  refined at 2.7 A, to crystallographic R factors of 20.4% and 24.25.1% for Rwork and  Rfree, respectively. Analysis of crystal contacts using the PISA software   [36] suggested that the biologically active molecule is a  homo-tetramer possessing D2 symmetry (Fig. 2A). CAS2 crystallized in the F222 space group  with one monomer occupying the asymmetric unit, and the structure was refined at 1.8 A,  to final Rwork of 19. 1% and Rfree of 21. 1%. Crystal contact analysis indicated an  equivalent homo-tetrameric oligomerization state to CAS1"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/03	2014/10/16	rogid:rjsVaZdgfnM1AxzZbxHzjxzq4vQ5147	rogid:rjsVaZdgfnM1AxzZbxHzjxzq4vQ5147	intact-crc:78ECD4507078DCBB|rigid:ISFy3QiEEcwtFG+VC+gKucD9ihg	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)