#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P20963 uniprotkb:Q8N2Q7 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-8287193|intact:MINT-1901478|uniprotkb:Q9UPT2|uniprotkb:D2X2H5 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:nlgn1_human(display_long)|uniprotkb:NLGN1(gene name)|psi-mi:NLGN1(display_short)|uniprotkb:KIAA1070(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N reactome:R-HSA-6794361|refseq:XP_016861387.1|refseq:XP_016861388.1|refseq:XP_016861389.1|refseq:XP_016861390.1|refseq:XP_005247291.1|refseq:XP_005247292.1|interpro:IPR019819|refseq:NP_055747.1|ensembl:ENST00000361589|ensembl:ENSP00000354541|ensembl:ENSG00000169760|ensembl:ENST00000457714|ensembl:ENSP00000392500|interpro:IPR030022|interpro:IPR029058|rcsb pdb:5OJ6|rcsb pdb:5OJK|go:"GO:0007399"(nervous system development)|go:"GO:0007416"(synapse assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010841"(positive regulation of circadian sleep/wake cycle, wakefulness)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032433"(filopodium tip)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048511"(rhythmic process)|go:"GO:0048789"(cytoskeletal matrix organization at active zone)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0072553"(terminal button organization)|go:"GO:0089717"(spanning component of membrane)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097115"(neurexin clustering involved in presynaptic membrane assembly)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098698"(postsynaptic specialization assembly)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098985"(asymmetric, glutamatergic, excitatory synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:0140058"(neuron projection arborization)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1902474"(positive regulation of protein localization to synapse)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905520"(positive regulation of presynaptic active zone assembly)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR000460(Neuroligin)|interpro:IPR002018(Carboxylesterase, type B) go:"GO:0005634"(nucleus) - comment:mint|function:Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:cQTCzkNad0DlgfAKsytNlA85TdA9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q0IIN5 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-7307723|intact:MINT-4651923 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q0iin5_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N mint:Q0IIN5|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR041569 go:"GO:0005634"(nucleus) - comment:mint figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:ixCtCYmG71XcgzQfGXt4y+rjNQk9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q5U0I6 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512746|uniprotkb:D6W5F3 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q5u0i6_human(display_long)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:hCG_22592(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_004152.1|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016477"(cell migration)|go:"GO:0032402"(melanosome transport)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042470"(melanosome) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q86SE5 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-741520|uniprotkb:Q6ZW87|uniprotkb:Q8N1C2|uniprotkb:B3KTH2|ensembl:ENSP00000428667|ensembl:ENSP00000430367|ensembl:ENSP00000430394|uniprotkb:G3V129 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:ralyl_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein C-like 3(gene name synonym)|uniprotkb:RALYL(gene name)|psi-mi:RALYL(display_short)|uniprotkb:HNRPCL3(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_001093861.1|refseq:NP_001093862.1|refseq:NP_001093863.1|refseq:NP_776247.3|ensembl:ENSG00000184672(gene)|ensembl:ENST00000521268(transcript)|ensembl:ENST00000521695(transcript)|ensembl:ENST00000522455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR034504|interpro:IPR035979|mint:Q86SE5|refseq:NP_001274173.1|refseq:XP_016868548.1|refseq:XP_016868549.1|refseq:XP_016868550.1|refseq:XP_016868551.1|refseq:XP_016868552.1|refseq:XP_016868553.1|refseq:XP_016868554.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:/dJc0rSACk93SMMAkFSfi2YdWuo9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q01844 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q53GL6 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512693|intact:EBI-11981785|intact:EBI-12745019 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q53gl6_human(display_long)|uniprotkb:RALY(gene name)|psi-mi:RALY(display_short)|uniprotkb:hCG_37136(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_057951.1|interpro:IPR034502|go:"GO:0003723"(RNA binding)|go:"GO:0042802"(identical protein binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:VuzMV/c8YsOBd9DpUo7LHHntrbY9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q4ADV7 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-2824467|uniprotkb:Q4VXJ9|uniprotkb:Q9H9S1|uniprotkb:Q4VXJ8|uniprotkb:Q8N6E0|uniprotkb:Q8TEH4|uniprotkb:Q76MT5|uniprotkb:Q9H0A5|intact:EBI-28978317|ensembl:ENSP00000416696|uniprotkb:B2RN24|uniprotkb:B7ZM67|uniprotkb:G5E932 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:ric1_human(display_long)|uniprotkb:RIC1(gene name)|psi-mi:RIC1(display_short)|uniprotkb:CIP150(gene name synonym)|uniprotkb:RAB6A-GEF complex partner protein 1(gene name synonym)|uniprotkb:Connexin-43-interacting protein of 150 kDa(gene name synonym)|uniprotkb:KIAA1432(gene name synonym)|uniprotkb:Protein RIC1 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N ensembl:ENST00000251879|ensembl:ENSP00000251879|ensembl:ENSP00000416696|ensembl:ENSP00000402240|ensembl:ENST00000418622|ensembl:ENSG00000107036(gene)|ensembl:ENST00000414202(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003330"(regulation of extracellular matrix constituent secretion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034066"(Ric1-Rgp1 guanyl-nucleotide exchange factor complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:1903363"(negative regulation of cellular protein catabolic process)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR009771(Protein of unknown function DUF1339)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR040096|reactome:R-HSA-6811438|reactome:R-HSA-6811440|reactome:R-HSA-8876198|refseq:NP_001129392.2|refseq:NP_001193486.1|refseq:NP_065880.2 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:qI8TYDOD6XWlUMzeqKZ2CFUPpL09606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q92621 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-1045046|uniprotkb:Q86YC1|uniprotkb:A6H8X3|ensembl:ENSP00000285968 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:nu205_human(display_long)|uniprotkb:Nucleoporin Nup205(gene name synonym)|uniprotkb:205 kDa nucleoporin(gene name synonym)|uniprotkb:NUP205(gene name)|psi-mi:NUP205(display_short)|uniprotkb:C7orf14(gene name synonym)|uniprotkb:KIAA0225(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N ensembl:ENSG00000155561(gene)|ensembl:ENST00000285968(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR021827|mint:Q92621|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:NP_055950.1|refseq:NP_001316363.1|dip:DIP-44021N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:5lulE2tOZ4V1UZPwkEvOo9reZWE9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q15269 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-722224|uniprotkb:Q96A77|uniprotkb:B2RAG8|ensembl:ENSP00000291576 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:pwp2_human(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:PWP2H(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_005040.2|refseq:XP_006723973.1|refseq:XP_011507205.1|ensembl:ENSG00000241945(gene)|ensembl:ENST00000291576(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|reactome:R-HSA-6790901|reactome:R-HSA-6791226 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:PYs2LKd3EMjAnp0engZvZn0CeBo9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q7KYM9 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512683 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q7kym9_human(display_long)|uniprotkb:ORF(gene name)|psi-mi:ORF(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR024667|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034990|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:rFMVlrNeuF71PIu8NZoawuj1ohk9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P42704 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q71UI9 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-2954755|ensembl:ENSP00000308405|uniprotkb:A8MQC5|uniprotkb:Q6PK98|uniprotkb:Q59GV8|uniprotkb:A6NN01|uniprotkb:A6NKY0|uniprotkb:A6NFA8 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:h2av_human(display_long)|uniprotkb:H2AZ2(gene name)|psi-mi:H2AZ2(display_short)|uniprotkb:H2A.F/Z(gene name synonym)|uniprotkb:H2A.Z variant histone 2(gene name synonym)|uniprotkb:H2AFV(gene name synonym)|uniprotkb:H2AV(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR007125(Histone core)|interpro:IPR002119(Histone H2A)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:3WAA|rcsb pdb:6M4D|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-9018519|ensembl:ENSG00000105968(gene)|ensembl:ENST00000308153(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|refseq:NP_036544.1|refseq:NP_619541.1|refseq:NP_958844.1|refseq:NP_958924.1|refseq:NP_958925.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:HWEdsnxjwV2Z0BAbsziMwaE/gXE9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q6PL18 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-6598454|ensembl:ENSP00000287394|uniprotkb:Q14CR1|uniprotkb:Q658P2|uniprotkb:Q68CQ0|uniprotkb:Q6PJV6|uniprotkb:Q8N890|uniprotkb:Q9UHS5 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:atad2_human(display_long)|uniprotkb:ATAD2(gene name)|psi-mi:ATAD2(display_short)|uniprotkb:AAA nuclear coregulator cancer-associated protein(gene name synonym)|uniprotkb:L16(orf name)|uniprotkb:PRO2000(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N ensembl:ENSG00000156802(gene)|ensembl:ENST00000287394(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001487(Bromodomain)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR031252|interpro:IPR036427|interpro:IPR041569|mint:Q6PL18|rcsb pdb:3DAI|rcsb pdb:4QSP|rcsb pdb:4QSQ|rcsb pdb:4QSR|rcsb pdb:4QSS|rcsb pdb:4QST|rcsb pdb:4QSU|rcsb pdb:4QSV|rcsb pdb:4QSW|rcsb pdb:4QSX|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4TT2|rcsb pdb:4TT4|rcsb pdb:4TT6|rcsb pdb:4TTE|rcsb pdb:4TU4|rcsb pdb:4TU6|rcsb pdb:4TYL|rcsb pdb:4TZ2|rcsb pdb:4TZ8|rcsb pdb:5A5N|rcsb pdb:5A5O|rcsb pdb:5A5P|rcsb pdb:5A5Q|rcsb pdb:5A5R|rcsb pdb:5A81|rcsb pdb:5A82|rcsb pdb:5A83|rcsb pdb:5EPB|rcsb pdb:5F36|rcsb pdb:5F3A|rcsb pdb:5LJ0|rcsb pdb:5QXI|rcsb pdb:5QXJ|rcsb pdb:5QXK|rcsb pdb:5QXL|rcsb pdb:5QXM|rcsb pdb:5QXN|rcsb pdb:5QXO|rcsb pdb:5QXP|rcsb pdb:5QXQ|rcsb pdb:5QXR|rcsb pdb:5QXS|rcsb pdb:5QXT|rcsb pdb:5QXU|rcsb pdb:5QXV|rcsb pdb:5QXW|rcsb pdb:5QXX|rcsb pdb:5QXY|rcsb pdb:5QXZ|rcsb pdb:5QY0|rcsb pdb:5R4E|rcsb pdb:5R4F|rcsb pdb:5R4V|rcsb pdb:5R4W|rcsb pdb:5R4X|rcsb pdb:5R4Y|rcsb pdb:5R4Z|rcsb pdb:6CPS|rcsb pdb:6EPJ|rcsb pdb:6EPR|rcsb pdb:6EPS|rcsb pdb:6EPT|rcsb pdb:6EPU|rcsb pdb:6EPV|rcsb pdb:6EPW|rcsb pdb:6EPX|rcsb pdb:6HDN|rcsb pdb:6HDO|rcsb pdb:6HI3|rcsb pdb:6HI4|rcsb pdb:6HI5|rcsb pdb:6HI6|rcsb pdb:6HI7|rcsb pdb:6HI8|rcsb pdb:6HIA|rcsb pdb:6HIB|rcsb pdb:6HIC|rcsb pdb:6HID|rcsb pdb:6HIE|rcsb pdb:6S55|rcsb pdb:6S56|rcsb pdb:6S57|rcsb pdb:6YB4|reactome:R-HSA-8866910|refseq:NP_054828.2|dip:DIP-46197N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:77ErLV8pp0aYjhfYutjO3AbsN6g9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P62805 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P55209 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q13609 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512718|uniprotkb:B2R8B1|uniprotkb:B7Z707|uniprotkb:O75803|ensembl:ENSP00000378053 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:dnsl3_human(display_long)|uniprotkb:DNASE1L3(gene name)|psi-mi:DNASE1L3(display_short)|uniprotkb:DHP2(gene name synonym)|uniprotkb:DNAS1L3(gene name synonym)|uniprotkb:DNase I homolog protein DHP2(gene name synonym)|uniprotkb:Deoxyribonuclease I-like 3(gene name synonym)|uniprotkb:Liver and spleen DNase(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_001243489.1|refseq:NP_004935.1|ensembl:ENSG00000163687(gene)|ensembl:ENST00000394549(transcript)|go:"GO:0000737"(DNA catabolic process, endonucleolytic)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002673"(regulation of acute inflammatory response)|go:"GO:0003677"(DNA binding)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0070948"(regulation of neutrophil mediated cytotoxicity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR016202(Deoxyribonuclease I-like)|interpro:IPR018057|interpro:IPR033125|interpro:IPR036691 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:867Q1lcN+drwOqlHlmf6SwCy1KU9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P63241 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-373150|uniprotkb:P10159|uniprotkb:Q16182|uniprotkb:Q7L7L3|uniprotkb:Q7Z4L1|uniprotkb:Q9D0G2|uniprotkb:A8K9A0|uniprotkb:D3DTP2|ensembl:ENSP00000336776|ensembl:ENSP00000390677|ensembl:ENSP00000396073|ensembl:ENSP00000458269|ensembl:ENSP00000459196|ensembl:ENSP00000459611|ensembl:ENSP00000499855|ensembl:ENSP00000499995|ensembl:ENSP00000500414|ensembl:ENSP00000500624|ensembl:ENSP00000500717|ensembl:ENSP00000500847 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:if5a1_human(display_long)|uniprotkb:EIF5A(gene name)|psi-mi:EIF5A(display_short)|uniprotkb:Eukaryotic initiation factor 5A isoform 1(gene name synonym)|uniprotkb:eIF-4D(gene name synonym)|uniprotkb:Rev-binding factor(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_001137232.1|refseq:NP_001137233.1|refseq:NP_001137234.1|refseq:NP_001961.1|refseq:XP_005256566.1|ensembl:ENSG00000132507(gene)|ensembl:ENSG00000288145(gene)|ensembl:ENST00000336458(transcript)|ensembl:ENST00000416016(transcript)|ensembl:ENST00000419711(transcript)|ensembl:ENST00000571955(transcript)|ensembl:ENST00000573542(transcript)|ensembl:ENST00000576930(transcript)|ensembl:ENST00000672250(transcript)|ensembl:ENST00000672755(transcript)|ensembl:ENST00000673099(transcript)|ensembl:ENST00000673210(transcript)|ensembl:ENST00000673259(transcript)|ensembl:ENST00000673304(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0098586"(cellular response to virus)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|mint:P63241|rcsb pdb:1FH4|rcsb pdb:3CPF|rcsb pdb:5DLQ|reactome:R-HSA-204626 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:/smk81DLs+XvrqXmIZpfvdHHauk9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q00839 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q4ZG72 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512704 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q4zg72_human(display_long)|uniprotkb:DDX18(gene name)|psi-mi:DDX18(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR044773|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR025313|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR027417|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:epWqn12bZVLZCoOwLJwIFuk0yQo9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q08211 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P26641 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:A8K8A6 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512573 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:a8k8a6_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012604(RBM1CTR)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR035979|go:"GO:0003723"(RNA binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:RarfapCxZbxDoBrtIlqrxbP6GtU9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P05141 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B2R4C1 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512654 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b2r4c1_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:rP5focw6BeeTe/ocTTgz03BYRlQ9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B3KWX7 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512601 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b3kwx7_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR029123|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:J2BW5oEOM74yyaQwQvdenw9WWuU9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:D3DS95 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512583 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:d3ds95_human(display_long)|uniprotkb:hCG_21173(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020784|interpro:IPR036796|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:yYhJK4Lsrx2FUGZGm1cdDwLNIV89606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:O95036 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-6190520 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:o95036_human(display_long)|uniprotkb:"WUGSC:H_RG054D04.1"(gene name)|psi-mi:"WUGSC:H_RG054D04.1"(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR018038|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:/Wx1NRwTL4OL8HlPLKeaZ568pCA9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:O15519 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-514941|ensembl:ENSP00000312455|ensembl:ENSP00000399420|uniprotkb:Q53TS6|uniprotkb:O14673|uniprotkb:O14674|uniprotkb:O14675|uniprotkb:O15137|uniprotkb:O15138|uniprotkb:O15356|uniprotkb:O15510|uniprotkb:O43618|uniprotkb:O43619|uniprotkb:O43620|uniprotkb:O60458|uniprotkb:O60459|uniprotkb:Q96TE4|uniprotkb:Q9UEW1|uniprotkb:Q54AF1|uniprotkb:B7Z9F9|uniprotkb:B4DJE0 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:cflar_human(display_long)|uniprotkb:Cellular FLICE-like inhibitory protein(gene name synonym)|uniprotkb:Caspase-eight-related protein(gene name synonym)|uniprotkb:Caspase-like apoptosis regulatory protein(gene name synonym)|uniprotkb:MACH-related inducer of toxicity(gene name synonym)|uniprotkb:Caspase homolog(gene name synonym)|uniprotkb:Inhibitor of FLICE(gene name synonym)|uniprotkb:FADD-like antiapoptotic molecule 1(gene name synonym)|uniprotkb:Usurpin(gene name synonym)|uniprotkb:CFLAR(gene name)|psi-mi:CFLAR(display_short)|uniprotkb:CASH(gene name synonym)|uniprotkb:CLARP(gene name synonym)|uniprotkb:MRIT(gene name synonym)|uniprotkb:CASP8AP1(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N ensembl:ENSG00000003402(gene)|ensembl:ENST00000309955(transcript)|ensembl:ENST00000423241(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014842"(regulation of skeletal muscle satellite cell proliferation)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0042060"(wound healing)|refseq:NP_001120655.1|refseq:NP_001120656.1|refseq:NP_001189444.1|refseq:NP_001189445.1|refseq:NP_001189446.1|refseq:NP_001189447.1|refseq:NP_001189448.1|refseq:NP_003870.4|refseq:NP_001294971.1|refseq:XP_016860681.1|refseq:XP_016860683.1|refseq:XP_016860679.1|refseq:XP_016860680.1|refseq:XP_016860682.1|refseq:XP_016860684.1|refseq:XP_016860685.1|refseq:XP_016860686.1|refseq:XP_016860687.1|dip:DIP-27629N|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0072126"(positive regulation of glomerular mesangial cell proliferation)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0097342"(ripoptosome)|go:"GO:1901740"(negative regulation of myoblast fusion)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001875(Death effector)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|rcsb pdb:2N5R|rcsb pdb:3H11|rcsb pdb:3H13|rcsb pdb:6M6O|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357905|reactome:R-HSA-69416|reactome:R-HSA-75158 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:kpksW8E51awRfZkhWEGFlrdgnJ89606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P31943 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:O75367 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-2868511|uniprotkb:Q7Z5E3|uniprotkb:Q9UP96|uniprotkb:Q9H8P3|uniprotkb:Q503A8|uniprotkb:O75377|uniprotkb:Q96D41|ensembl:ENSP00000423563|ensembl:ENSP00000424971 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:h2ay_human(display_long)|uniprotkb:MACROH2A1(gene name)|psi-mi:MACROH2A1(display_short)|uniprotkb:H2AFY(gene name synonym)|uniprotkb:Histone H2A.y(gene name synonym)|uniprotkb:Medulloblastoma antigen MU-MB-50.205(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:XP_011542031.1|refseq:XP_011542032.1|refseq:NP_001035248.1|refseq:NP_004884.1|refseq:NP_613075.1|refseq:NP_613258.2|dip:DIP-44283N|ensembl:ENSG00000113648(gene)|ensembl:ENST00000510038(transcript)|ensembl:ENST00000511689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000182"(rDNA binding)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0007549"(dosage compensation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902750"(negative regulation of cell cycle G2/M phase transition)|go:"GO:1902882"(regulation of response to oxidative stress)|go:"GO:1902883"(negative regulation of response to oxidative stress)|go:"GO:1902884"(positive regulation of response to oxidative stress)|go:"GO:1903226"(positive regulation of endodermal cell differentiation)|go:"GO:1904815"(negative regulation of protein localization to chromosome, telomeric region)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR021171|interpro:IPR032454|interpro:IPR035796|interpro:IPR043472|mint:O75367|rcsb pdb:1U35|rcsb pdb:1ZR3|rcsb pdb:1ZR5|rcsb pdb:2F8N|rcsb pdb:2FXK|rcsb pdb:3HQH|rcsb pdb:3HSV|rcsb pdb:3IID|rcsb pdb:3IIF|rcsb pdb:3IVB|rcsb pdb:5IIT|rcsb pdb:5LNC|interpro:IPR002119(Histone H2A) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:0FCoM0/4mTtnc7cPDUleKuZ3HgM9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B2RAU8 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512611 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b2rau8_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007718(SRP40, C-terminal)|refseq:NP_001271317.1|refseq:NP_004732.2 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:k1TDeGSCKb71IIYJNEeuLNf5FQA9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B4DLD4 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512642 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b4dld4_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|go:"GO:0003723"(RNA binding)|go:"GO:0006364"(rRNA processing)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:TBqXjUIhRduDoxX7t5tTsj4K8M49606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B2RBR9 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512631 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b2rbr9_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR000225(Armadillo)|interpro:IPR040122|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:3AWYgPEZ95Z9u8iCMflQ3CEGoyk9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:A8MXQ7 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512618|uniprotkb:A0A1B0GTG1|ensembl:ENSP00000489685 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:iqak1_human(display_long)|uniprotkb:IQANK1(gene name)|psi-mi:IQANK1(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N ensembl:ENSG00000203499(gene)|ensembl:ENST00000527139(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:2000812"(regulation of barbed-end actin filament capping)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR027417|interpro:IPR036770 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:TXH3q6IgA79tre2sVCaGdbJVkKc9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B3KNS7 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512624 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b3kns7_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR042099|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|refseq:NP_055977.3 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:9/fy0qybJvAv+L0YrwZjsJ/0MGk9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:O95433 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-448610|uniprotkb:Q9P060|uniprotkb:Q96IL6|uniprotkb:B2R9L2|uniprotkb:B4DUR9|ensembl:ENSP00000216479 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:ahsa1_human(display_long)|uniprotkb:HSPC322(orf name)|uniprotkb:p38(gene name synonym)|uniprotkb:AHSA1(gene name)|psi-mi:AHSA1(display_short)|uniprotkb:C14orf3(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_036243.1|refseq:NP_001308370.1|ensembl:ENSG00000100591(gene)|ensembl:ENST00000216479(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013538(Activator of Hsp90 ATPase homologue 1-like)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR023393|interpro:IPR036338|interpro:IPR039981|mint:O95433|rcsb pdb:1X53|rcsb pdb:7DMD|rcsb pdb:7DME|go:"GO:0051879"(Hsp90 protein binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:HUgJrOxubEHSPst5ZQNxSC38QvY9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:E9PM64 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512565|ensembl:ENSP00000433105 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:e9pm64_human(display_long)|uniprotkb:DNHD1(gene name)|psi-mi:DNHD1(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N ensembl:ENSG00000179532(gene)|ensembl:ENST00000524401(transcript)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|interpro:IPR024317|interpro:IPR026983|interpro:IPR027417 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:AqeEVE3+aqk5A1pwAzY5lED96RY9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B4E312 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512592 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b4e312_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036443|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR034870|interpro:IPR034875|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:ExbsvEdsgArBg7LEiysPehoLe1g9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P51991 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-1050760|uniprotkb:Q53RW7|uniprotkb:Q6URK5|uniprotkb:D3DPF4|ensembl:ENSP00000376309|ensembl:ENSP00000416340|ensembl:ENSP00000503593|ensembl:ENSP00000504135|ensembl:ENSP00000504152 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:roa3_human(display_long)|uniprotkb:HNRPA3(gene name synonym)|uniprotkb:HNRNPA3(gene name)|psi-mi:HNRNPA3(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_919223.1|refseq:NP_001317178.1|ensembl:ENSG00000170144(gene)|ensembl:ENST00000392524(transcript)|ensembl:ENST00000435711(transcript)|ensembl:ENST00000676629(transcript)|ensembl:ENST00000678111(transcript)|ensembl:ENST00000679159(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:P51991|reactome:R-HSA-72163|reactome:R-HSA-72203 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:bbg0nIdhEHomcwtgZhT2yHy7+nU9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B2RBB2 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512559 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b2rbb2_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR019540|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:7Z1Gvxp3xe+jCdUDPNLPMtF1bTQ9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B4DGR3 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512494 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b4dgr3_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0015031"(protein transport)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:6qXG5QpAL/5f11clbAIHjRRaL2k9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:A8K146 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512463 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:a8k146_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR036985|interpro:IPR004583(DNA repair protein Rad4)|interpro:IPR018026|interpro:IPR018325|interpro:IPR018326|interpro:IPR018327|interpro:IPR018328|interpro:IPR038765|interpro:IPR042488|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:2ZmHV9c39YBXIxwjHeZS6NWVtTw9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:A8K394 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-2555614 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:a8k394_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR026650|go:"GO:0000139"(Golgi membrane) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:C1bAw1bgO1g7/gJM4gjRLz1LMCY9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P20963 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P12821 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512350|uniprotkb:B0LPF0|uniprotkb:B4DXI3|uniprotkb:E7EU16|uniprotkb:P22966|uniprotkb:Q53YX9|uniprotkb:Q59GY8|uniprotkb:Q7M4L4|ensembl:ENSP00000290866 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:ace_human(display_long)|uniprotkb:ACE(gene name)|psi-mi:ACE(display_short)|uniprotkb:DCP(gene name synonym)|uniprotkb:DCP1(gene name synonym)|uniprotkb:Dipeptidyl carboxypeptidase I(gene name synonym)|uniprotkb:Kininase II(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_000780.1|refseq:NP_001171528.1|refseq:NP_690043.1|ensembl:ENSG00000159640(gene)|ensembl:ENST00000290866(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0002019"(regulation of renal output by angiotensin)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0003081"(regulation of systemic arterial blood pressure by renin-angiotensin)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0003779"(actin binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0008241"(peptidyl-dipeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0031404"(chloride ion binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031711"(bradykinin receptor binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032943"(mononuclear cell proliferation)|go:"GO:0042447"(hormone catabolic process)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0060047"(heart contraction)|go:"GO:0060177"(regulation of angiotensin metabolic process)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070573"(metallodipeptidase activity)|go:"GO:0071838"(cell proliferation in bone marrow)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1902033"(regulation of hematopoietic stem cell proliferation)|go:"GO:1903597"(negative regulation of gap junction assembly)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR001548(Peptidase M2, peptidyl-dipeptidase A)|mint:P12821|rcsb pdb:1O86|rcsb pdb:1O8A|rcsb pdb:1UZE|rcsb pdb:1UZF|rcsb pdb:2C6F|rcsb pdb:2C6N|rcsb pdb:2IUL|rcsb pdb:2IUX|rcsb pdb:2OC2|rcsb pdb:2XY9|rcsb pdb:2XYD|rcsb pdb:2YDM|rcsb pdb:3BKK|rcsb pdb:3BKL|rcsb pdb:3L3N|rcsb pdb:3NXQ|rcsb pdb:4APH|rcsb pdb:4APJ|rcsb pdb:4BXK|rcsb pdb:4BZR|rcsb pdb:4BZS|rcsb pdb:4C2N|rcsb pdb:4C2O|rcsb pdb:4C2P|rcsb pdb:4C2Q|rcsb pdb:4C2R|rcsb pdb:4CA5|rcsb pdb:4CA6|rcsb pdb:4UFA|rcsb pdb:4UFB|rcsb pdb:5AM8|rcsb pdb:5AM9|rcsb pdb:5AMA|rcsb pdb:5AMB|rcsb pdb:5AMC|rcsb pdb:6EN5|rcsb pdb:6EN6|rcsb pdb:6F9R|rcsb pdb:6F9T|rcsb pdb:6F9U|rcsb pdb:6F9V|rcsb pdb:6H5W|rcsb pdb:6H5X|rcsb pdb:6QS1|rcsb pdb:6TT1|rcsb pdb:6TT3|rcsb pdb:6TT4|rcsb pdb:6ZPQ|rcsb pdb:6ZPT|rcsb pdb:6ZPU|reactome:R-HSA-2022377 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:Ta44N/vjlStlVIzNX634OjHzyrM9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B2RDW1 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-2339597|uniprotkb:D6W5C9 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b2rdw1_human(display_long)|uniprotkb:HEL112(gene name)|psi-mi:HEL112(display_short)|uniprotkb:RPS27A(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym)|uniprotkb:Ubiquitin-40S ribosomal protein S27a(gene name synonym)|uniprotkb:hCG_1987923(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR038582|interpro:IPR029071|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0046872"(metal ion binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:O00154 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-948905|ensembl:ENSP00000367086|uniprotkb:O43703|uniprotkb:Q53Y78|uniprotkb:Q5JYL2|uniprotkb:Q5JYL3|uniprotkb:Q5JYL4|uniprotkb:Q5JYL5|uniprotkb:Q5JYL6|uniprotkb:Q5TGR4|uniprotkb:Q9UJM9|uniprotkb:Q9Y539|uniprotkb:Q9Y540|uniprotkb:A8K0K7|uniprotkb:A8K232|uniprotkb:A8K6B8|uniprotkb:A8K837|uniprotkb:B3KQ12 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:bach_human(display_long)|uniprotkb:Long chain acyl-CoA thioester hydrolase(gene name synonym)|uniprotkb:Acyl-CoA thioesterase 7(gene name synonym)|uniprotkb:CTE-IIa(gene name synonym)|uniprotkb:Brain acyl-CoA hydrolase(gene name synonym)|uniprotkb:BACH(gene name synonym)|uniprotkb:ACOT7(gene name)|psi-mi:ACOT7(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1900535"(palmitic acid biosynthetic process)|interpro:IPR006683(Thioesterase superfamily)|interpro:IPR029069|interpro:IPR033120|interpro:IPR040170|mint:O00154|rcsb pdb:2QQ2|reactome:R-HSA-77289|go:"GO:0047617"(acyl-CoA hydrolase activity)|ensembl:ENSG00000097021(gene)|ensembl:ENST00000377855(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0036114"(medium-chain fatty-acyl-CoA catabolic process)|go:"GO:0036116"(long-chain fatty-acyl-CoA catabolic process)|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_863655.1|refseq:NP_863656.1|refseq:NP_009205.3|refseq:NP_863654.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:Tv8nHSqfXMmzZqj71+Gec6+29/s9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B3KTV0 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512436 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b3ktv0_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|go:"GO:0005524"(ATP binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:iagOJXvSNF/P0CWdTBxGux9XQCQ9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:A0PJ87 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512484 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:a0pj87_human(display_long)|uniprotkb:RSL1D1(gene name)|psi-mi:RSL1D1(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR023674|interpro:IPR028364|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:sx8YTf8/dMKYsKw1CocheOH14P09606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:F5GX40 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512260|ensembl:ENSP00000441157 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:f5gx40_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N ensembl:ENSG00000253729(gene)|ensembl:ENST00000540819(transcript) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:0LFNFDR+KHg7YdVQMOEWJFC9C4g9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:A8K1L8 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512343 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:a8k1l8_human(display_long)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034520|interpro:IPR035979|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:5Vpe++CTB8PYcMwbehaHnAyNB049606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P82094 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-949763|uniprotkb:Q17R87|uniprotkb:B7ZLJ2|uniprotkb:Q59GK0|ensembl:ENSP00000381567 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:tmf1_human(display_long)|uniprotkb:TMF1(gene name)|psi-mi:TMF1(display_short)|uniprotkb:Androgen receptor coactivator 160 kDa protein(gene name synonym)|uniprotkb:ARA160(gene name synonym)|uniprotkb:Androgen receptor-associated protein of 160 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_009045.2|refseq:XP_011532358.1|dip:DIP-5933N|interpro:IPR022092|mint:P82094|reactome:R-HSA-6811440|ensembl:ENSG00000144747(gene)|ensembl:ENST00000398559(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001675"(acrosome assembly)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0032275"(luteinizing hormone secretion)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR022091 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:F+z+GIH0PWbFoueklDHM/lj55MI9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B2RXH8 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512317|uniprotkb:B7ZW41|ensembl:ENSP00000479203|ensembl:ENSP00000488742|ensembl:ENSP00000488781 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:hnrc2_human(display_long)|uniprotkb:HNRNPCL2(gene name)|psi-mi:HNRNPCL2(display_short)|uniprotkb:HNRNPCP5(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_001130033.3|ensembl:ENSG00000275774(gene)|ensembl:ENSG00000282530(gene)|ensembl:ENSG00000283370(gene)|ensembl:ENST00000621994(transcript)|ensembl:ENST00000633387(transcript)|ensembl:ENST00000633810(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:CRIx7b7+QSRz6txxf+RDle0/RUM9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q63ZY6 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512443|uniprotkb:A8K7U2|uniprotkb:Q3KQU7|uniprotkb:Q658S2|uniprotkb:Q6NZ66|uniprotkb:Q6PHS1|uniprotkb:Q8N727|uniprotkb:Q9HAH4 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:nsn5c_human(display_long)|uniprotkb:NSUN5P2(gene name)|psi-mi:NSUN5P2(display_short)|uniprotkb:NSUN5C(gene name synonym)|uniprotkb:WBSCR20B(gene name synonym)|uniprotkb:WBSCR20C(gene name synonym)|uniprotkb:NOL1/NOP2/Sun domain family member 5C(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 20C protein(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR023267|interpro:IPR029063|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0070475"(rRNA base methylation) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:K5XrMDHHz0iRIVsuxGS4ckiCN9o9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:A2BDK6 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512329 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:a2bdk6_human(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short)|uniprotkb:hCG_37848(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_001311184.1|interpro:IPR026074|interpro:IPR027321|interpro:IPR000102(Neuraxin/MAP1B repeat)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005874"(microtubule)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:xQQMuRpLti/Igs2dDH8sHEOvOps9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P84550 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512282|uniprotkb:A6NIP4|uniprotkb:A6NJY0|uniprotkb:Q2VWA5|ensembl:ENSP00000369374 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:skor1_human(display_long)|uniprotkb:SKOR1(gene name)|psi-mi:SKOR1(display_short)|uniprotkb:CORL1(gene name synonym)|uniprotkb:FUSSEL15(gene name synonym)|uniprotkb:LBXCOR1(gene name synonym)|uniprotkb:Functional Smad-suppressing element on chromosome 15(gene name synonym)|uniprotkb:LBX1 corepressor 1(gene name synonym)|uniprotkb:Ladybird homeobox corepressor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:XP_016877662.1|refseq:NP_001244953.1|ensembl:ENSG00000188779(gene)|ensembl:ENST00000380035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046332"(SMAD binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028762|interpro:IPR037000 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:wXSmTaF6yWlhrASoq+JE9kV0K9c9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P06748 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:A8K6V3 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512475 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:a8k6v3_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9512492|imex:IM-23088-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|refseq:NP_036558.3|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR018846|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2020/08/15 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:dVGS0qMrgg4y1EfI6o4R0OGkK1k9606 intact-crc:61F925108362C239|rigid:nKp6J/jSetNbwhLrlWllyq5e07Q false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q8NET4 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-3951768|uniprotkb:Q9P2M8|ensembl:ENSP00000419786|ensembl:ENSP00000441452 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:rtl9_human(display_long)|uniprotkb:RTL9(gene name)|psi-mi:RTL9(display_short)|uniprotkb:KIAA1318(gene name synonym)|uniprotkb:RGAG1(gene name synonym)|uniprotkb:Retrotransposon gag domain-containing protein 1(gene name synonym)|uniprotkb:Tumor antigen BJ-HCC-23(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) ensembl:ENSP00000419786|ensembl:ENSP00000441452|refseq:XP_011529300.1|refseq:XP_011529301.1|ensembl:ENSG00000243978(gene)|ensembl:ENST00000465301(transcript)|ensembl:ENST00000540313(transcript)|interpro:IPR042919|refseq:NP_065820.1|refseq:XP_016885183.1|refseq:XP_016885184.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:+4fqg+HwycXTrZbuudfitWu1AZI9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:A4FU77 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-7845893|intact:MINT-4654800 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:a4fu77_human(display_long)|uniprotkb:SNRNP200(gene name)|psi-mi:SNRNP200(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR036388|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR027417|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR041094|interpro:IPR035892|interpro:IPR036390 go:"GO:0005634"(nucleus) - comment:"fragmentation type: fragment"|comment:mint|comment:homomint figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:PtjnR3cGOhQAf1IICsqzN7qFjn89606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:A3RJH1 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-8456352|intact:MINT-4839470 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:a3rjh1_human(display_long)|uniprotkb:DDX1(gene name)|psi-mi:DDX1(display_short)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:hCG_15914(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|refseq:NP_004930.1|interpro:IPR027417|interpro:IPR043136|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0051607"(defense response to virus)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:n2Zv07BpuUDT32/ttDzIFXH3yIQ9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q7L2H7 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-353901|intact:EBI-4289539|intact:EBI-715219|uniprotkb:Q2F836|uniprotkb:Q53HL6|uniprotkb:Q9BXW1|uniprotkb:O60735|uniprotkb:A8K7X4|intact:EBI-2559366|ensembl:ENSP00000436049|intact:EBI-373200|uniprotkb:B4E2Q4 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:eif3m_human(display_long)|uniprotkb:EIF3M(gene name)|psi-mi:EIF3M(display_short)|uniprotkb:HFLB5(gene name synonym)|uniprotkb:PCID1(gene name synonym)|uniprotkb:PCI domain-containing protein 1(gene name synonym)|uniprotkb:Fetal lung protein B5(gene name synonym)|uniprotkb:GA17(orf name)|uniprotkb:PNAS-125(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_006351.2|refseq:NP_001294858.1|ensembl:ENSG00000149100(gene)|ensembl:ENST00000531120(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027528|interpro:IPR036390|interpro:IPR040750|mint:Q7L2H7|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31256N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:siTfTDezqWL90pw6xG3xUKfY9n49606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B2RCF3 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513230 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b2rcf3_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR022677|interpro:IPR022678|interpro:IPR022676|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0006499"(N-terminal protein myristoylation) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:zIWoTmBJTzxzgb6u1LXpZ6Dx2BA9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q15366 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 intact:EBI-2949729 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 - psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:dg2l7_human(display_short)|psi-mi:EBI-2949729(display_long)|uniprotkb:DGAT2L7P(gene name)|psi-mi:DGAT2L7P(display_short)|uniprotkb:Diacylglycerol O-acyltransferase 2-like 7 pseudogene(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) uniprotkb:Q6IED9(uniprot-removed-ac) go:"GO:0005634"(nucleus) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:OPFahuMYw601cESZJcQOVK0KSec9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P27824 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q9BSJ8 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P62917 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q02878 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q2M1Z1 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513077 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q2m1z1_human(display_long)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short)|uniprotkb:hCG_20493(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR042120|interpro:IPR042121|interpro:IPR038973|refseq:NP_055196.2|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR028830|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR036890|interpro:IPR037198|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:zDBpP6TZVvYP4zTb0YY7KS0uFEE9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P55061 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-1045825|uniprotkb:O14938|uniprotkb:Q643A7|uniprotkb:Q96J50|uniprotkb:F8W034|uniprotkb:B2R5M4|ensembl:ENSP00000267115|ensembl:ENSP00000378454|ensembl:ENSP00000448036|ensembl:ENSP00000450158 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:bi1_human(display_long)|uniprotkb:Testis-enhanced gene transcript protein(gene name synonym)|uniprotkb:Transmembrane BAX inhibitor motif-containing protein 6(gene name synonym)|uniprotkb:TMBIM6(gene name)|psi-mi:TMBIM6(display_short)|uniprotkb:BI1(gene name synonym)|uniprotkb:TEGT(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_001092046.1|refseq:NP_003208.2|ensembl:ENSG00000139644(gene)|ensembl:ENST00000267115(transcript)|ensembl:ENST00000395006(transcript)|ensembl:ENST00000549385(transcript)|ensembl:ENST00000552370(transcript)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0060698"(endoribonuclease inhibitor activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR006213(Bax inhibitor 1, conserved site)|interpro:IPR006214(Protein of unknown function UPF0005)|mint:P55061|refseq:XP_005269183.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:l3wlIZarKWk471gkb6A5Jy/gN/U9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q6F5E8 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513063|uniprotkb:B8X2Z3|ensembl:ENSP00000334958 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:carl2_human(display_long)|uniprotkb:CARMIL2(gene name)|psi-mi:CARMIL2(display_short)|uniprotkb:Capping protein regulator and myosin 1 linker 2(gene name synonym)|uniprotkb:F-actin-uncapping protein RLTPR(gene name synonym)|uniprotkb:LRRC16C(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 16C(gene name synonym)|uniprotkb:RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein(gene name synonym)|uniprotkb:RLTPR(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_001303955.1|refseq:NP_001013860.1|ensembl:ENSG00000159753(gene)|ensembl:ENST00000334583(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031252"(cell leading edge)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051639"(actin filament network formation)|go:"GO:0061339"(establishment or maintenance of monopolar cell polarity)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1902745"(positive regulation of lamellipodium organization)|go:"GO:2000813"(negative regulation of barbed-end actin filament capping)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029763|interpro:IPR031943|interpro:IPR041245|mint:Q6F5E8 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:gAT9BXBiOtVtPa/z6R0XqY0/H/49606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P15822 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_002105.3|ensembl:ENSG00000095951(gene)|ensembl:ENST00000379388(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:rugwzqsTO0X8mJ5Zy3msTqc6dr09606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q7Z3N6 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513240 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q7z3n6_human(display_long)|uniprotkb:DKFZp686A01173(gene name)|psi-mi:DKFZp686A01173(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR036961|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0016459"(myosin complex) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:+V+JPsi9Pcg2/vXYCidtEXUxvE89606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P09493 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-351158|uniprotkb:P09494|uniprotkb:P10469|uniprotkb:Q86W64|uniprotkb:Q96IK2|uniprotkb:Q9Y427|uniprotkb:Q9UCY9|uniprotkb:Q6DV89|uniprotkb:Q6DV90|uniprotkb:Q9UCI1|uniprotkb:Q9UCI2|uniprotkb:B7Z5T7|uniprotkb:Q7Z6L8|intact:EBI-2558177|ensembl:ENSP00000385107|intact:EBI-11030042|uniprotkb:D9YZV2|uniprotkb:D9YZV3|uniprotkb:D9YZV8 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:tpm1_human(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:TMSA(gene name synonym)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)|uniprotkb:C15orf13(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_000357.3|refseq:NP_001018005.1|refseq:NP_001018006.1|refseq:NP_001018008.1|ensembl:ENSG00000140416(gene)|ensembl:ENST00000403994(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032059"(bleb)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000533(Tropomyosin)|mint:P09493|rcsb pdb:3MUD|rcsb pdb:5KHT|rcsb pdb:6UT2|rcsb pdb:6X5Z|reactome:R-HSA-390522|reactome:R-HSA-445355|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_001288173.1|refseq:NP_001018007.1|refseq:NP_001018004.1|refseq:NP_001018020.1|refseq:XP_016878027.1|refseq:NP_001317273.1|refseq:NP_001317275.1|refseq:NP_001317280.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:rsKuZnKpbEqVOpYBz3PnoSBCSHs9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B4DDS7 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513128 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b4dds7_human(display_long)|uniprotkb:SRP54(gene name)|psi-mi:SRP54(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR042101|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR004125(Signal recognition particle, SRP54 subunit, M-domain)|interpro:IPR022941|interpro:IPR006325(Signal recognition particle, SRP54 subunit)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR036225|interpro:IPR036891|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0016607"(nuclear speck) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:qukhqeW5HV5BnN47x3bo/VmWboA9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P33993 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q14257 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P62937 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-437708|uniprotkb:P05092|uniprotkb:Q3KQW3|uniprotkb:Q6IBU5|uniprotkb:Q96IX3|uniprotkb:Q9BRU4|uniprotkb:Q9BTY9|uniprotkb:Q9UC61|uniprotkb:Q567Q0|ensembl:ENSP00000419425|uniprotkb:A8K220 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:ppia_human(display_long)|uniprotkb:Cyclophilin A(gene name synonym)|uniprotkb:Cyclosporin A-binding protein(gene name synonym)|uniprotkb:PPIA(gene name)|psi-mi:PPIA(display_short)|uniprotkb:CYPA(gene name synonym)|uniprotkb:Rotamase A(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_066953.1|interpro:IPR029000|mint:P62937|rcsb pdb:1AK4|rcsb pdb:1AWQ|rcsb pdb:1AWR|rcsb pdb:1AWS|rcsb pdb:1AWT|rcsb pdb:1AWU|rcsb pdb:1AWV|rcsb pdb:1BCK|rcsb pdb:1CWA|rcsb pdb:1CWB|rcsb pdb:1CWC|rcsb pdb:1CWF|rcsb pdb:1CWH|rcsb pdb:1CWI|rcsb pdb:1CWJ|rcsb pdb:1CWK|rcsb pdb:1CWL|rcsb pdb:1CWM|interpro:IPR024936|rcsb pdb:1CWO|rcsb pdb:1FGL|rcsb pdb:2N0T|rcsb pdb:2RMA|rcsb pdb:1M63|rcsb pdb:2RMB|rcsb pdb:2X25|rcsb pdb:2X2A|rcsb pdb:2X2C|rcsb pdb:2X2D|rcsb pdb:1M9C|rcsb pdb:1M9D|rcsb pdb:1M9E|rcsb pdb:2XGY|rcsb pdb:3CYH|rcsb pdb:3CYS|rcsb pdb:3K0M|rcsb pdb:3K0N|rcsb pdb:3K0O|rcsb pdb:3K0P|rcsb pdb:3K0Q|rcsb pdb:3K0R|rcsb pdb:3ODI|rcsb pdb:3ODL|rcsb pdb:1M9F|rcsb pdb:3RDD|rcsb pdb:1M9X|rcsb pdb:1M9Y|rcsb pdb:4CYH|rcsb pdb:4IPZ|rcsb pdb:4N1M|rcsb pdb:4N1N|rcsb pdb:1MF8|rcsb pdb:4N1O|rcsb pdb:4N1P|rcsb pdb:4N1Q|rcsb pdb:1MIK|rcsb pdb:1NMK|rcsb pdb:1OCA|rcsb pdb:1RMH|rcsb pdb:1VBS|rcsb pdb:1VBT|rcsb pdb:1W8L|rcsb pdb:1W8M|rcsb pdb:1W8V|rcsb pdb:1YND|rcsb pdb:1ZKF|rcsb pdb:2ALF|rcsb pdb:2CPL|rcsb pdb:2CYH|rcsb pdb:2MS4|rcsb pdb:2MZU|rcsb pdb:4N1R|rcsb pdb:4N1S|rcsb pdb:4YUG|rcsb pdb:4YUH|refseq:NP_001287910.1|reactome:R-HSA-210991|reactome:R-HSA-6798695|reactome:R-HSA-8950505|reactome:R-HSA-2025928|ensembl:ENSG00000196262(gene)|ensembl:ENST00000468812(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0019076"(viral release from host cell)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031982"(vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046790"(virion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0061944"(negative regulation of protein K48-linked ubiquitination)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903901"(negative regulation of viral life cycle)|go:"GO:1904399"(heparan sulfate binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|go:"GO:0005178"(integrin binding)|rcsb pdb:4YUI|rcsb pdb:4YUJ|rcsb pdb:4YUK|rcsb pdb:4YUL|rcsb pdb:4YUM|rcsb pdb:4YUN|rcsb pdb:4YUO|rcsb pdb:4YUP|rcsb pdb:5CYH|rcsb pdb:5F66|rcsb pdb:5FJB|rcsb pdb:5KUL|rcsb pdb:5KUN|rcsb pdb:5KUO|rcsb pdb:5KUQ|rcsb pdb:5KUR|rcsb pdb:5KUS|rcsb pdb:5KUU|rcsb pdb:5KUV|rcsb pdb:5KUW|rcsb pdb:5KUZ|rcsb pdb:5KV0|rcsb pdb:5KV1|rcsb pdb:5KV2|rcsb pdb:5KV3|rcsb pdb:5KV4|rcsb pdb:5KV5|rcsb pdb:5KV6|rcsb pdb:5KV7|rcsb pdb:5LUD|rcsb pdb:5NOQ|rcsb pdb:5NOR|rcsb pdb:5NOT|rcsb pdb:5NOU|rcsb pdb:5NOV|rcsb pdb:5NOW|rcsb pdb:5NOX|rcsb pdb:5NOY|rcsb pdb:5NOZ|rcsb pdb:5T9U|rcsb pdb:5T9W|rcsb pdb:5T9Z|rcsb pdb:5TA2|rcsb pdb:5TA4|rcsb pdb:5WC7|rcsb pdb:6BTA|rcsb pdb:6GJI|rcsb pdb:6GJJ|rcsb pdb:6GJL|rcsb pdb:6GJM|rcsb pdb:6GJN|rcsb pdb:6GJP|rcsb pdb:6GJR|rcsb pdb:6GJY|rcsb pdb:6GS6|rcsb pdb:6I42|rcsb pdb:6U5C|rcsb pdb:6U5D|rcsb pdb:6U5E|rcsb pdb:6U5G|rcsb pdb:6X3R|rcsb pdb:6X3Y|rcsb pdb:5NOS|rcsb pdb:6X4N|rcsb pdb:6X4O|rcsb pdb:6X4P|rcsb pdb:6X4Q|rcsb pdb:6Y9V|rcsb pdb:6Y9W|rcsb pdb:6Y9X|rcsb pdb:6Y9Y|rcsb pdb:6Y9Z|rcsb pdb:6ZDJ|rcsb pdb:7ABT|reactome:R-HSA-114608|reactome:R-HSA-162585|reactome:R-HSA-162588|reactome:R-HSA-162592|reactome:R-HSA-162594|reactome:R-HSA-164516|reactome:R-HSA-164525|reactome:R-HSA-173107|rcsb pdb:6X4M|reactome:R-HSA-175474|reactome:R-HSA-180689|dip:DIP-6080N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:dr4EVxcO+sqTPBqsQcydRn+rHoo9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:O60884 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q3B7A7 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513143 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q3b7a7_human(display_long)|uniprotkb:GART(gene name)|psi-mi:GART(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR004733(Phosphoribosylformylglycinamidine cyclo-ligase)|interpro:IPR016188(PurM, N-terminal-like)|interpro:IPR004607(Phosphoribosylglycinamide formyltransferase)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR036477|interpro:IPR036676|interpro:IPR036921|interpro:IPR037123|go:"GO:0004637"(phosphoribosylamine-glycine ligase activity)|go:"GO:0004641"(phosphoribosylformylglycinamidine cyclo-ligase activity)|go:"GO:0004644"(phosphoribosylglycinamide formyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0046872"(metal ion binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:wLeOwlIJPuOT/a1lTlArYhCoElg9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B4DSR6 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513049 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b4dsr6_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR026983|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008569"(minus-end-directed microtubule motor activity) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:9jecYU23u6Lv5cBszmN0mKvb+f09606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B0I1T2 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-2857637|uniprotkb:Q96RI5|uniprotkb:Q8TEI9|uniprotkb:Q96RI6|uniprotkb:Q8TES2|uniprotkb:Q96BE2|ensembl:ENSP00000258787 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:myo1g_human(display_long)|uniprotkb:MYO1G(gene name)|psi-mi:MYO1G(display_short)|uniprotkb:HA2(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_149043.2|ensembl:ENSG00000136286(gene)|ensembl:ENST00000258787(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031982"(vesicle)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071976"(cell gliding)|go:"GO:0072678"(T cell migration)|go:"GO:0120117"(T cell meandering migration)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:B0I1T2|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030175"(filopodium) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:9VsQfp7AsKTN+3jpHkAWsSbNoxc9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:O00303 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q96SI9 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-740355|uniprotkb:Q32NB9|uniprotkb:Q9BUE1|uniprotkb:Q9BXG4|uniprotkb:Q9H0B4|uniprotkb:Q9H7V1|uniprotkb:Q9NUK4|ensembl:ENSP00000321347|ensembl:ENSP00000415968 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:strbp_human(display_long)|uniprotkb:STRBP(gene name)|psi-mi:STRBP(display_short)|uniprotkb:SPNR(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_001164608.1|refseq:NP_060857.2|ensembl:ENSG00000165209(gene)|ensembl:ENST00000348403(transcript)|ensembl:ENST00000447404(transcript)|go:"GO:0002177"(manchette)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008017"(microtubule binding)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR030446|interpro:IPR043519|interpro:IPR044472|rcsb pdb:2DMY|refseq:XP_016870383.1|refseq:XP_016870384.1|refseq:XP_016870385.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:xVEZqCqBcH0MBB1Ar9SU+9Yhsbs9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B4DNQ8 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513260 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b4dnq8_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:7naTwwuTiB0pKy523qu46GU8uv89606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B2RCI8 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513189 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b2rci8_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR037671|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR007070(GPI ethanolamine phosphate transferase 1)|interpro:IPR017852(GPI ethanolamine phosphate transferase 1, C-terminal)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051377"(mannose-ethanolamine phosphotransferase activity) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:vqLEEWPSpfGry59S4lnyC+XQyFU9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P68133 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-367510|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSP00000355645|uniprotkb:Q5T8M9 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:acts_human(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) ensembl:ENSG00000143632(gene)|ensembl:ENST00000366684(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043531"(ADP binding)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68133|reactome:R-HSA-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001091.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q6PKG0 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-1052114|uniprotkb:O94836|uniprotkb:Q8N4M2|uniprotkb:Q8NB73|uniprotkb:Q9UFD7|ensembl:ENSP00000428589 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:larp1_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)|uniprotkb:KIAA0731(gene name synonym)|uniprotkb:LARP(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_056130.2|ensembl:ENST00000336314|ensembl:ENSP00000336721|ensembl:ENSP00000428589|refseq:XP_005268461.1|ensembl:ENSG00000155506(gene)|ensembl:ENST00000518297(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008494"(translation activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|mint:Q6PKG0|rcsb pdb:4ZC4|rcsb pdb:5C0V|rcsb pdb:5V4R|rcsb pdb:5V7C|rcsb pdb:5V87|rcsb pdb:6PW3 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:TjQrZVRN3opAdFIWZtaEopFZf8I9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:A4D1N4 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513208 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:a4d1n4_human(display_long)|uniprotkb:CHCHD3(gene name)|psi-mi:CHCHD3(display_short)|uniprotkb:hCG_2014841(orf name)|uniprotkb:tcag7.1158(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_060282.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0060090"(molecular adaptor activity) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:Ox0+PoTPYwxw8cKNqpzvSCg+Smg9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q53GB0 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513057 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q53gb0_human(display_long)|uniprotkb:Translocase of outer membrane 22 kDa subunit homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR005683(Mitochondrial import translocase, subunit Tom22)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:g+eHOIA2nSN8JknUN2nFDnta9i49606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q2F834 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513116 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q2f834_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005509"(calcium ion binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:eu7NErAuJiGUXwp9nQ2Vkq2j1oA9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B2R643 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513268 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b2r643_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR036961|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|refseq:NP_001242970.1|interpro:IPR036072|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0016459"(myosin complex) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:XBCOx2OWFzSasfpS6REeOOz6BR09606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P57059 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-1181640|uniprotkb:A6NC84|uniprotkb:Q5R2V5|uniprotkb:Q6ZNL8|uniprotkb:Q86YJ2|ensembl:ENSP00000270162 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:sik1_human(display_long)|uniprotkb:SIK(gene name synonym)|uniprotkb:SIK1(gene name)|psi-mi:SIK1(display_short)|uniprotkb:SNF1LK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SNF1-like kinase 1(gene name synonym)|uniprotkb:Salt-inducible kinase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_775490.2|refseq:NP_001307572.1|ensembl:ENSG00000142178(gene)|ensembl:ENST00000270162(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010830"(regulation of myotube differentiation)|go:"GO:0010868"(negative regulation of triglyceride biosynthetic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048511"(rhythmic process)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017090(Serine/threonine-protein kinase, SNF1-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034672|reactome:R-HSA-400253 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:dBsqqf2AK+XNle2pJN/ydonP30U9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q8NDP4 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-747580|uniprotkb:Q8IYZ7|uniprotkb:Q96SU1|ensembl:ENSP00000305077 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:zn439_human(display_long)|uniprotkb:ZNF439(gene name)|psi-mi:ZNF439(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_689475.1|ensembl:ENST00000304030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_001335653.1|refseq:NP_001335654.1|ensembl:ENSG00000171291(gene) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:UVKDti4OX5K5L7slheBd+/PEUQg9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P04899 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-353997|uniprotkb:Q8IZ71|intact:EBI-2563889|uniprotkb:B4DYA0|intact:EBI-4404691|uniprotkb:Q6B6N3|uniprotkb:B3KTZ0|uniprotkb:B4E2X5|ensembl:ENSP00000312999 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:gnai2_human(display_long)|uniprotkb:GNAI2(gene name)|psi-mi:GNAI2(display_short)|uniprotkb:GNAI2B(gene name synonym)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_002061.1|refseq:NP_001269546.1|refseq:NP_001269549.1|refseq:NP_001269547.1|refseq:NP_001269548.1|refseq:NP_001159897.1|dip:DIP-602N|ensembl:ENSG00000114353(gene)|ensembl:ENST00000313601(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:0030425"(dendrite)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:6D9H|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|mint:P04899 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:Mi3PAXudkdPb375bOi7luNAmUaU9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q6WCQ1 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-1022605|uniprotkb:Q3KQZ5|uniprotkb:Q5FB94|uniprotkb:Q6DHW2|uniprotkb:Q7Z5Y2|uniprotkb:Q8N390|uniprotkb:Q96G40|ensembl:ENSP00000342379 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:mprip_human(display_long)|uniprotkb:MRIP(gene name synonym)|uniprotkb:Rho-interacting protein 3(gene name synonym)|uniprotkb:p116Rip(gene name synonym)|uniprotkb:MPRIP(gene name)|psi-mi:MPRIP(display_short)|uniprotkb:KIAA0864(gene name synonym)|uniprotkb:RHOIP3(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) ensembl:ENSG00000133030(gene)|ensembl:ENST00000341712(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|mint:Q6WCQ1|reactome:R-HSA-6802952|refseq:NP_055949.2|refseq:NP_958431.2 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:QoGbbg2ehuQogDM1Dlxzw6xj59s9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q9Y608 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-1023718|uniprotkb:Q68CV3|uniprotkb:Q9NXH5|uniprotkb:A8K649|uniprotkb:A8MXR0|uniprotkb:B4DY63|ensembl:ENSP00000338727 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:lrrf2_human(display_long)|uniprotkb:LRRFIP2(gene name)|psi-mi:LRRFIP2(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_001127841.1|refseq:NP_006300.1|refseq:NP_060194.1|refseq:XP_011532519.1|refseq:XP_011532520.1|refseq:XP_011532521.1|refseq:NP_001269620.1|ensembl:ENSG00000093167(gene)|ensembl:ENST00000336686(transcript)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030275"(LRR domain binding)|interpro:IPR019139|mint:Q9Y608|refseq:XP_005265596.1|refseq:XP_005265597.1|refseq:XP_016862973.1|refseq:NP_001335239.1|refseq:NP_001335240.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:ma/crL7UY91uJ8bqLfkX3K8aQLI9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P62424 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B3KTS5 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513251 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b3kts5_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR023614|interpro:IPR030270|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR027246|refseq:NP_003365.1|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:xRPCSK9A5DzfTEZ6/w70Ou8nEcY9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q2F837 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513180 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q2f837_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005525"(GTP binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:i2HqEoZenrd19PuzqvMw2CwKGqQ9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P49407 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:F1T0L7 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513174 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:f1t0l7_human(display_long)|uniprotkb:ANO2(gene name)|psi-mi:ANO2(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR032394|interpro:IPR007632(Protein of unknown function DUF590)|refseq:NP_001265525.1|interpro:IPR031288|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046983"(protein dimerization activity) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:tHXqqDF1mtdAFUp84xPCxtHyIOs9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B7Z7U6 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513097 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b7z7u6_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_001272389.1|refseq:NP_001272390.1|refseq:NP_006624.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR023152|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036872|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:JPwRzC0fENuEHnDPYHAVMjp8Ybk9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:D0PNI1 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513280 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:d0pni1_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:HEL-S-3(gene name synonym)|uniprotkb:HEL4(gene name synonym)|uniprotkb:HEL-S-93(gene name synonym)|uniprotkb:hCG_2009146(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:XP_016869299.1|refseq:XP_016869300.1|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|interpro:IPR036815|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006605"(protein targeting)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0035148"(tube formation)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q53EP4 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9513200 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q53ep4_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513358|imex:IM-23088-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR007676(Ribophorin I)|go:"GO:0006486"(protein glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:6VVVvpqIvvLVEJIDvZhA/bNSfQU9606 intact-crc:8AE021D9D205D183|rigid:dhihNrCAegXGZvHRPYoEogu6ukM false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P35249 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-476655|uniprotkb:Q6FHX7|ensembl:ENSP00000296273|ensembl:ENSP00000376272|uniprotkb:D3DNV2|uniprotkb:B4DM41 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:rfc4_human(display_long)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:Replication factor C 37 kDa subunit(gene name synonym)|uniprotkb:Activator 1 37 kDa subunit(gene name synonym)|uniprotkb:RFC4(gene name)|psi-mi:RFC4(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_002907.1|refseq:NP_853551.1|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000163918(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|ensembl:ENST00000296273(transcript)|ensembl:ENST00000392481(transcript)|mint:P35249|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-176187|dip:DIP-24267N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:zn+V998ZRpYIdHmG87ExC6LFc0w9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q5JR94 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-8456376|intact:MINT-4999522 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q5jr94_human(display_long)|uniprotkb:RPS8(gene name)|psi-mi:RPS8(display_short)|uniprotkb:hCG_2031852(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR018283|refseq:NP_001003.1|interpro:IPR022309|interpro:IPR001047(Ribosomal protein S8e)|interpro:IPR042563|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:3rpCBdQyRWR+TCKnupbnCp30jKE9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:D3DQ69 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512984 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:d3dq69_human(display_long)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:hCG_2032021(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR032381|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR039764|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:0BdyUKO9Nz4CT++TZHRHKv25VUg9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B5BUB1 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512878 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b5bub1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR037938|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR027238|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR041048|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:aBcJKlV75E/3Ht94Dp+scTxvelc9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q9BQ67 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-351000|uniprotkb:Q8TF59|ensembl:ENSP00000253237|intact:EBI-9512815|uniprotkb:A0MNN5 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:grwd1_human(display_long)|uniprotkb:GRWD1(gene name)|psi-mi:GRWD1(display_short)|uniprotkb:GRWD(gene name synonym)|uniprotkb:WDR28(gene name synonym)|uniprotkb:KIAA1942(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR022052|refseq:NP_113673.3|ensembl:ENSG00000105447(gene)|ensembl:ENST00000253237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|mint:Q9BQ67|interpro:IPR036322 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:rbkcKHsv+l3kFqh4SElBDft0b+A9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q5W0A0 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512788|uniprotkb:Q96MB5|ensembl:ENSP00000298738 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:eri6b_human(display_long)|uniprotkb:FAM194B(gene name synonym)|uniprotkb:Protein FAM194B(gene name synonym)|uniprotkb:ERICH6B(gene name)|psi-mi:ERICH6B(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:XP_016875907.1|refseq:NP_872348.2|ensembl:ENSG00000165837(gene)|ensembl:ENST00000298738(transcript)|interpro:IPR029281 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:tHA9Ld1OVkr6AW1Z/4VEykIfR5E9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q99729 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B7Z2W3 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512801 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b7z2w3_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:1gU44NuaztFaYBVAbnnoEiTw71U9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:A4QPB0 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512851 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:a4qpb0_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR036872|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR027417|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR023152|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR001202(WW/Rsp5/WWP)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:a0mVdpfSxREiuldxbb8re3BA5GA9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q53G83 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9373522 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q53g83_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR001351(Ribosomal protein S3, C-terminal)|interpro:IPR004044(K Homology, type 2)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR018280|interpro:IPR036419|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005819"(spindle)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0051301"(cell division)|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity") go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:YFzsiKVAKnnIT1zndT6eD3btGhs9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q6ZU52 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-739493|uniprotkb:O43158|uniprotkb:Q5TF20|uniprotkb:Q7L2M2|ensembl:ENSP00000435150|uniprotkb:B3KRE5|uniprotkb:E1P573 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:k0408_human(display_long)|uniprotkb:KIAA0408(gene name)|psi-mi:KIAA0408(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_055517.3|ensembl:ENSG00000189367(gene)|ensembl:ENST00000483725(transcript)|interpro:IPR027882|mint:Q6ZU52|ensembl:ENSP00000435150 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:Ys9F4yIzuccTYU42mOIlc/I4yYo9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q1JQ76 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512916 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q1jq76_human(display_long)|uniprotkb:RPL10A(gene name)|psi-mi:RPL10A(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR023674|interpro:IPR028364|interpro:IPR023673|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:eyigPpL2ZP8inzhuJ7zqmFAGiuE9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B2R5W2 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512830|ensembl:ENSP00000404559 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b2r5w2_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) ensembl:ENSG00000092199(gene)|ensembl:ENST00000449098(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:mw5fsmHFd1vShnA7PPP6bZDT0Qs9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:O00763 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-2211739|uniprotkb:A6NK36|uniprotkb:Q16852|uniprotkb:Q1HEC1|uniprotkb:Q6KE87|uniprotkb:Q6KE89|uniprotkb:Q6TY48|intact:EBI-28983570|ensembl:ENSP00000341044|ensembl:ENSP00000367079 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:acacb_human(display_long)|uniprotkb:ACACB(gene name)|psi-mi:ACACB(display_short)|uniprotkb:ACC2(gene name synonym)|uniprotkb:ACCB(gene name synonym)|uniprotkb:ACC-beta(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:XP_011536561.1|refseq:XP_006719430.1|ensembl:ENSP00000341044|ensembl:ENSP00000367079|refseq:NP_001084.3|refseq:XP_005253933.1|dip:DIP-51617N|ensembl:ENSG00000076555(gene)|ensembl:ENST00000338432(transcript)|ensembl:ENST00000377848(transcript)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031999"(negative regulation of fatty acid beta-oxidation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060421"(positive regulation of heart growth)|go:"GO:0097009"(energy homeostasis)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|mint:O00763|rcsb pdb:2DN8|rcsb pdb:2HJW|rcsb pdb:2KCC|rcsb pdb:3FF6|rcsb pdb:3GID|rcsb pdb:3GLK|rcsb pdb:3JRW|rcsb pdb:3JRX|rcsb pdb:3TDC|rcsb pdb:4HQ6|rcsb pdb:5KKN|reactome:R-HSA-163765|reactome:R-HSA-196780|reactome:R-HSA-200425|reactome:R-HSA-2426168 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:P4hgekQx/AZz4InTWHW6u6jpDRA9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q9Y623 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-2511704|ensembl:ENSP00000255381 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:myh4_human(display_long)|uniprotkb:MYH4(gene name)|psi-mi:MYH4(display_short)|uniprotkb:Myosin heavy chain 4(gene name synonym)|uniprotkb:Myosin heavy chain 2b(gene name synonym)|uniprotkb:Myosin heavy chain IIb(gene name synonym)|uniprotkb:Myosin heavy chain, skeletal muscle, fetal(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) ensembl:ENSG00000264424(gene)|ensembl:ENST00000255381(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0032982"(myosin filament)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|go:"GO:0005859"(muscle myosin complex)|refseq:NP_060003.2|refseq:XP_016880165.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:7zD8Mcq4iGSoiy7hj6AyKDzesRQ9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q96JI7 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-2822128|ensembl:ENSP00000261866|uniprotkb:Q4VC11|uniprotkb:Q9H734|uniprotkb:Q8TBU9|uniprotkb:Q6NW01|uniprotkb:Q58G86|uniprotkb:Q69YG6|uniprotkb:Q8N270|uniprotkb:A8KAX9|uniprotkb:B9EK60|uniprotkb:F5H3N6 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:sptcs_human(display_long)|uniprotkb:SPG11(gene name)|psi-mi:SPG11(display_short)|uniprotkb:KIAA1840(gene name synonym)|uniprotkb:Colorectal carcinoma-associated protein(gene name synonym)|uniprotkb:Spastic paraplegia 11 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045202"(synapse)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048675"(axon extension)|go:"GO:0090389"(phagosome-lysosome fusion involved in apoptotic cell clearance)|go:"GO:0090659"(walking behavior)|interpro:IPR028103|interpro:IPR028107|ensembl:ENSG00000104133(gene)|ensembl:ENST00000261866(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0030424"(axon)|refseq:NP_001153699.1|refseq:NP_079413.3 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:MBwFM40VJDnLVyuFV9HNn2Qx7mI9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P36873 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-356283|ensembl:ENSP00000335084 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P62847 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-354515|uniprotkb:P16632|uniprotkb:Q7Z3D1|uniprotkb:Q5T0P7|uniprotkb:Q5T0P8|uniprotkb:E7EPK6|ensembl:ENSP00000478869 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:rs24_human(display_long)|uniprotkb:RPS24(gene name)|psi-mi:RPS24(display_short)|uniprotkb:Small ribosomal subunit protein eS24(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_001135757.1|refseq:NP_001017.1|refseq:NP_001135755.1|refseq:NP_148982.1|ensembl:ENSG00000138326(gene)|ensembl:ENST00000613865(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001976(Ribosomal protein S24e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR018098|mint:P62847|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6XA1|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:M/qkRxabHx9PFaOM7EwKDOOwu7Q9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B2R935 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512840 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b2r935_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR036388|interpro:IPR036390|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR041083|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0051301"(cell division) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:NyDuFU8Du8mwjPNqZWZsLMdKJ4k9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q6IAX1 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512930 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q6iax1_human(display_long)|uniprotkb:FDFT1(gene name)|psi-mi:FDFT1(display_short)|uniprotkb:hCG_17749(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR044844|interpro:IPR033904|refseq:NP_001274671.1|refseq:NP_001274672.1|refseq:NP_004453.3|interpro:IPR002060(Squalene/phytoene synthase)|interpro:IPR006449(Farnesyl-diphosphate farnesyltransferase)|interpro:IPR019845|interpro:IPR008949(Terpenoid synthase)|go:"GO:0004310"(farnesyl-diphosphate farnesyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0045338"(farnesyl diphosphate metabolic process)|go:"GO:0051996"(squalene synthase activity) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:3TjanjXw3X58/ZOEsB1xczV0/qQ9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B7Z8W3 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512993 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b7z8w3_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR029978|interpro:IPR031865|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036034|interpro:IPR036872|go:"GO:0016021"(integral component of membrane)|go:"GO:0023051"(regulation of signaling)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0046872"(metal ion binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:3Bb4Qj/Y/pWjY1zXtswGc4zsGxo9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P28340 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-716569|uniprotkb:Q8NER3|uniprotkb:Q96H98|ensembl:ENSP00000406046|ensembl:ENSP00000472600|ensembl:ENSP00000473052 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:dpod1_human(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:DNA polymerase subunit delta p125(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short)|uniprotkb:POLD(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_002682.2|refseq:XP_011525340.1|refseq:NP_001243778.1|ensembl:ENSG00000062822(gene)|ensembl:ENST00000599857(transcript)|ensembl:ENST00000601098(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0009411"(response to UV)|ensembl:ENST00000440232(transcript)|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-5358606|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019899"(enzyme binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017964|interpro:IPR023211|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|mint:P28340|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|reactome:R-HSA-110314|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-2564830|reactome:R-HSA-5358565|refseq:XP_016882370.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:bJ5Q0xOzHga/zxMOBHkuXaFXeLw9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B2R6K4 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512905 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b2r6k4_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR036322|interpro:IPR020472|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007165"(signal transduction) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:ZtfUWwknfA5wN76hQq5BE+gqad49606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B5BUE6 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512888 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b5bue6_human(display_long)|uniprotkb:Probable ATP-dependent RNA helicase DDX5(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR027417|interpro:IPR012587(P68HR)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005524"(ATP binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:I9gCCvZFwMHh7il5MOI75Uzvf0c9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:O75369 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-352089|intact:EBI-1754974|uniprotkb:Q13706|uniprotkb:Q59EC2|uniprotkb:Q6MZJ1|uniprotkb:Q8WXS9|uniprotkb:Q8WXT0|uniprotkb:Q8WXT1|uniprotkb:Q8WXT2|uniprotkb:Q9NRB5|uniprotkb:B2ZZ84|uniprotkb:Q9NT26|uniprotkb:Q9UEV9|intact:EBI-1960054|uniprotkb:C9JKE6|uniprotkb:B2ZZ85|uniprotkb:C9JMC4|ensembl:ENSP00000295956|uniprotkb:B2ZZ83|uniprotkb:Q60FE7|uniprotkb:Q8WXT3 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:flnb_human(display_long)|uniprotkb:FLNB(gene name)|psi-mi:FLNB(display_short)|uniprotkb:FLN1L(gene name synonym)|uniprotkb:FLN3(gene name synonym)|uniprotkb:TABP(gene name synonym)|uniprotkb:TAP(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Thyroid autoantigen(gene name synonym)|uniprotkb:Truncated actin-binding protein(gene name synonym)|uniprotkb:ABP-280 homolog(gene name synonym)|uniprotkb:ABP-278(gene name synonym)|uniprotkb:Filamin-3(gene name synonym)|uniprotkb:Filamin homolog 1(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_001157791.1|refseq:NP_001448.2|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:O75369|rcsb pdb:2DI8|rcsb pdb:2DI9|rcsb pdb:2DIA|rcsb pdb:2DIB|rcsb pdb:2DIC|rcsb pdb:2DJ4|rcsb pdb:2DLG|rcsb pdb:2DMB|rcsb pdb:2DMC|rcsb pdb:2E9I|rcsb pdb:2E9J|rcsb pdb:2EE6|rcsb pdb:2EE9|rcsb pdb:2EEA|rcsb pdb:2EEB|rcsb pdb:2EEC|rcsb pdb:2EED|rcsb pdb:2WA5|rcsb pdb:2WA6|rcsb pdb:2WA7|rcsb pdb:3FER|rcsb pdb:4B7L|rcsb pdb:5DCP|reactome:R-HSA-1169408|ensembl:ENSG00000136068(gene)|ensembl:ENST00000295956(transcript)|go:"GO:0001725"(stress fiber)|refseq:NP_001157789.1|refseq:NP_001157790.1 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:lsf6C/Vg0io7UhUi1Kapgwp0p5E9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:A4D1I1 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512975 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:a4d1i1_human(display_long)|uniprotkb:LOC402287(gene name)|psi-mi:LOC402287(display_short)|uniprotkb:tcag7.1261(orf name) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR001593(Ribosomal protein S3Ae)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:eFgzuWQhbFvLjs6jsHluBvIi37I9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P08238 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q7Z5A3 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512868 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q7z5a3_human(display_long)|uniprotkb:SNRPD1(gene name)|psi-mi:SNRPD1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR034102|interpro:IPR027141|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:fMErMfzyoZiSyrU6TmO+PSVYKFw9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q96I99 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-2511878|ensembl:ENSP00000307432|uniprotkb:Q8WUQ1|uniprotkb:Q86VX8|uniprotkb:O95195|uniprotkb:Q6NUH7|uniprotkb:C9JVT2 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:sucb2_human(display_long)|uniprotkb:SUCLG2(gene name)|psi-mi:SUCLG2(display_short)|uniprotkb:GTP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-G chain(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) ensembl:ENSG00000172340(gene)|ensembl:ENST00000307227(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045244"("succinate-CoA ligase complex (GDP-forming)")|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034722|mint:Q96I99|rcsb pdb:6WCV|reactome:R-HSA-71403|refseq:NP_001171070.1|refseq:NP_003839.2|dip:DIP-53563N go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:jxrFGuu3hFn2QAYfrPxTKhScM249606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:A8K651 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512810 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:a8k651_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR036561|interpro:IPR003428(Mitochondrial glycoprotein)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:Jd/FA2BQ4Eah0rGwo1KdxSEGJt89606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:Q59FC6 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512947 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:q59fc6_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR020575|interpro:IPR020568|interpro:IPR036890|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:jaOShiFcDT+g8nziW+HwLW/qauI9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:O75976 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-3916308|uniprotkb:B7Z7T9|uniprotkb:B7ZAU4|uniprotkb:F5GZH6|uniprotkb:Q86SH9|uniprotkb:O15377|uniprotkb:Q86XE6|ensembl:ENSP00000225719 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:cbpd_human(display_long)|uniprotkb:CPD(gene name)|psi-mi:CPD(display_short)|uniprotkb:Metallocarboxypeptidase D(gene name synonym)|uniprotkb:gp180(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_001295.2|refseq:NP_001186704.1|interpro:IPR015567(Peptidase M14B, caboxypeptidase D unit2)|interpro:IPR033848|interpro:IPR034224|mint:O75976|rcsb pdb:5AQ0|reactome:R-HSA-432722|reactome:R-HSA-9696264|reactome:R-HSA-9696273|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|ensembl:ENSG00000108582(gene)|ensembl:ENST00000225719(transcript)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000834(Peptidase M14, carboxypeptidase A) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:PC6PFm4D7KoT4utNwyIe57VUwbY9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B2R6K0 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512959 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b2r6k0_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR032189|interpro:IPR038973|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR036890|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:YScZQs3xDWr2LuCGaW1Wq7HUBWY9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P62854 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-353438|uniprotkb:P02383|uniprotkb:Q3MHD8|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:Q6IRY4|ensembl:ENSP00000348849|ensembl:ENSP00000450339|ensembl:ENSP00000496643 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:rs26_human(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)|uniprotkb:Small ribosomal subunit protein eS26(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_001020.2|refseq:XP_005276741.1|rcsb pdb:6OLG|rcsb pdb:6OLF|ensembl:ENST00000356464(transcript)|ensembl:ENST00000552361(transcript)|ensembl:ENST00000646449(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|mint:P62854|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G5H|ensembl:ENSG00000197728(gene)|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-156827 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:P51148 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689|ensembl:ENSP00000377440 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_004574.2|refseq:NP_958842.1|refseq:XP_011523392.1|refseq:XP_011523393.1|refseq:NP_001238968.1|ensembl:ENSG00000108774(gene)|ensembl:ENST00000346213(transcript)|ensembl:ENST00000393860(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0019003"(GDP binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042470"(melanosome)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198 go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B3KW06 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512795 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b3kw06_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR032691|interpro:IPR032629|interpro:IPR026829|interpro:IPR016024(Armadillo-type fold)|go:"GO:0015031"(protein transport) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:84BwtoW57J7bM5cwEZLJFC4uSic9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20963 uniprotkb:B2R7W4 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-9512778 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:b2r7w4_human(display_long) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513422|imex:IM-23088-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034411|interpro:IPR041337|go:"GO:0003723"(RNA binding) go:"GO:0005634"(nucleus) - - figure legend:st1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2017/03/30 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:rE78XL0WAG9YQknKev1kp6PBqKs9606 intact-crc:6998EAF056436446|rigid:VGdQiIyVFMr7Ji85mmEtStXm/lg false phosphorylated residue:72-72,83-83|biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P49407 uniprotkb:P20963 intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym) psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9513574|imex:IM-23088-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) - - - figure legend:f1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 intact-crc:6EFB7A642B35CFA7|rigid:50McILzL3gxcxnkBfQG3KSlv4l0 false - phosphorylated residue:142-142,153-153|biotin tag:n-n|binding-associated region:137-160 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P20963 uniprotkb:P49407 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9513550|imex:IM-23088-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N - - - figure legend:f1dv|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606 intact-crc:7BDD7054BF0A7BCE|rigid:50McILzL3gxcxnkBfQG3KSlv4l0 false binding-associated region:106-129|biotin tag:n-n - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P49407 uniprotkb:P20963 intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym) psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9513562|imex:IM-23088-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) - - - figure legend:f1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 intact-crc:6DCC7A4FF5E2F72A|rigid:50McILzL3gxcxnkBfQG3KSlv4l0 false - biotin tag:n-n|binding-associated region:67-90|phosphorylated residue:72-72,83-83 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P20963 uniprotkb:P49407 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513485|imex:IM-23088-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N - - - figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606 intact-crc:18278DD5462DAB16|rigid:Qqt9SyKXfyTmTerkfG0FQN9R04I false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P20963 uniprotkb:P46459 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513485|imex:IM-23088-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2 - - - figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606 intact-crc:18278DD5462DAB16|rigid:Qqt9SyKXfyTmTerkfG0FQN9R04I false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P20963 uniprotkb:Q00610 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513485|imex:IM-23088-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424 - - - figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606 intact-crc:18278DD5462DAB16|rigid:Qqt9SyKXfyTmTerkfG0FQN9R04I false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P20963 uniprotkb:P55072 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513485|imex:IM-23088-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N - - - figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606 intact-crc:18278DD5462DAB16|rigid:Qqt9SyKXfyTmTerkfG0FQN9R04I false biotin tag:n-n|binding-associated region:67-90 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P20963 uniprotkb:Q00610 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513509|imex:IM-23088-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424 - - - figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606 intact-crc:3FB3E2499AC55DE6|rigid:fQ9TaseAjxrJpFmhlUHjgWPOfvY false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P20963 uniprotkb:P55072 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513509|imex:IM-23088-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N - - - figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606 intact-crc:3FB3E2499AC55DE6|rigid:fQ9TaseAjxrJpFmhlUHjgWPOfvY false biotin tag:n-n|binding-associated region:137-160|phosphorylated residue:142-142,153-153 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P20963 uniprotkb:P55072 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513497|imex:IM-23088-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N - - - figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606 intact-crc:15CAE4C5E038B779|rigid:fQ9TaseAjxrJpFmhlUHjgWPOfvY false binding-associated region:67-90|biotin tag:n-n|phosphorylated residue:72-72,83-83 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P20963 uniprotkb:Q00610 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9513497|imex:IM-23088-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424 - - - figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606 intact-crc:15CAE4C5E038B779|rigid:fQ9TaseAjxrJpFmhlUHjgWPOfvY false binding-associated region:67-90|biotin tag:n-n|phosphorylated residue:72-72,83-83 - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P20963 uniprotkb:P49407 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9513525|imex:IM-23088-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N - - - figure legend:f1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606 intact-crc:B8E3611E72D0B296|rigid:50McILzL3gxcxnkBfQG3KSlv4l0 false binding-associated region:67-90|biotin tag:n-n - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P20963 uniprotkb:P49407 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym) psi-mi:"MI:0096"(pull down) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9514853|imex:IM-23088-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM) refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N - - - figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606 intact-crc:55AA6355C53AD772|rigid:50McILzL3gxcxnkBfQG3KSlv4l0 false his tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P24161 uniprotkb:Q8BWG8 intact:EBI-7803400|uniprotkb:P29020|ensembl:ENSMUSP00000005907|intact:MINT-7895650|uniprotkb:Q9D3G3 intact:EBI-641778|uniprotkb:Q3UH95|uniprotkb:Q8BTJ5|ensembl:ENSMUSP00000095866 psi-mi:cd3z_mouse(display_long)|uniprotkb:Cd247(gene name)|psi-mi:Cd247(display_short)|uniprotkb:Cd3z(gene name synonym)|uniprotkb:Tcrz(gene name synonym)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym) psi-mi:arrb1_mouse(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:Arrb1(gene name)|psi-mi:Arrb1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9513593|imex:IM-23088-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237047.1|refseq:NP_112439.1|refseq:XP_017168774.1|ensembl:ENSMUSG00000005763(gene)|ensembl:ENSMUST00000005907(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|interpro:IPR024128|reactome:R-MMU-198933|reactome:R-MMU-202424|reactome:R-MMU-202427|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-2029481|reactome:R-MMU-2029482|reactome:R-MMU-2029485|reactome:R-MMU-389948|mint:P24161|refseq:NP_001106862.1 refseq:NP_796205.1|refseq:NP_835738.1|dip:DIP-49444N|ensembl:ENSMUSG00000018909(gene)|ensembl:ENSMUST00000098266(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:Q8BWG8|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-456926|reactome:R-MMU-5635838|reactome:R-MMU-5674135|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-418555 - comment:mint - figure legend:f1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-lymphoblast)|taxid:10090(Mus musculus) - 2014/04/28 2014/10/16 rogid:Ac52AvET/m0LboX+dKOOhfmE4B010090 rogid:QnjSypgRI1Aym+xBu3vpHxVSAD010090 intact-crc:8BBB15AAA5AE1F26|rigid:La4oB/j0GwfkRoboMZbK68brEeI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49407 uniprotkb:P20963 intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym) psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9513604|imex:IM-23088-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N - - - figure legend:f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jurkat)|taxid:9606(Homo sapiens) - 2014/04/28 2014/12/01 rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 intact-crc:AD7070A5C1CCD242|rigid:50McILzL3gxcxnkBfQG3KSlv4l0 false binding-associated region:319-418|green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49407 uniprotkb:P20963 intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym) psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9515038|imex:IM-23088-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N go:"GO:0001772"(immunological synapse) comment:"We assessed the role of b-Arr1 in mediating CXCR4 translocation to the IS by analyzing Jurkat cells stimulated with superantigen- loaded APCs. In the presence of WT b-Arr1, CXCR4 localized with the TCR at the IS (Fig 7D), whereas expression of b-Arr1 (319- 418) induced the accumulation of both CXCR4 and the TCR in intracellular vesicles, preventing the accumulation of CXCR4 at the IS (Fig 7D)." - figure legend:sf6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jurkat)|taxid:9606(Homo sapiens) - 2014/04/28 2018/04/30 rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 intact-crc:BF1F18385C310C49|rigid:watnBVGaK5gqYfRaN6dnGBJzGIg false green fluorescent protein tag:?-?|binding-associated region:319-418 mcherry fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P49407 uniprotkb:P04435 intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581 intact:EBI-9515124|uniprotkb:A0A1B0GX54|ensembl:ENSP00000478301 psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym) psi-mi:tvb79_human(display_long)|uniprotkb:TRBV7-9(gene name)|psi-mi:TRBV7-9(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9515038|imex:IM-23088-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N ensembl:ENSG00000278030(gene)|ensembl:ENST00000612787(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042287"(MHC protein binding)|go:"GO:0042605"(peptide antigen binding)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-389948 go:"GO:0001772"(immunological synapse) comment:"We assessed the role of b-Arr1 in mediating CXCR4 translocation to the IS by analyzing Jurkat cells stimulated with superantigen- loaded APCs. In the presence of WT b-Arr1, CXCR4 localized with the TCR at the IS (Fig 7D), whereas expression of b-Arr1 (319- 418) induced the accumulation of both CXCR4 and the TCR in intracellular vesicles, preventing the accumulation of CXCR4 at the IS (Fig 7D)." - figure legend:sf6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jurkat)|taxid:9606(Homo sapiens) - 2014/04/28 2018/04/30 rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606 rogid:aUW+B6peJXWR4M5CYIQ7vrFpqGg9606 intact-crc:BF1F18385C310C49|rigid:watnBVGaK5gqYfRaN6dnGBJzGIg false green fluorescent protein tag:?-?|binding-associated region:319-418 - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0422"(immunostaining) uniprotkb:P29066 uniprotkb:P20963 intact:EBI-4303019|ensembl:ENSRNOP00000046069 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 psi-mi:arrb1_rat(display_long)|uniprotkb:Arrb1(gene name)|psi-mi:Arrb1(display_short)|uniprotkb:Arrestin beta-1(gene name synonym) psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9515155|imex:IM-23088-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2156|refseq:NP_037042.1|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P29066|rcsb pdb:4JQI|rcsb pdb:6KL7|rcsb pdb:6U1N|reactome:R-RNO-418555|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-456926|reactome:R-RNO-5635838|reactome:R-RNO-5674135|reactome:R-RNO-5689880|reactome:R-RNO-8856825|reactome:R-RNO-8856828|interpro:IPR011021(Arrestin-like, N-terminal)|ensembl:ENSRNOG00000030404(gene)|ensembl:ENSRNOT00000043554(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019899"(enzyme binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|dip:DIP-40808N|go:"GO:0001772"(immunological synapse) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N go:"GO:0030139"(endocytic vesicle) - - figure legend:f7d|comment:"We assessed the role of b-Arr1 in mediating CXCR4 translocation to the IS by analyzing Jurkat cells stimulated with superantigen- loaded APCs. In the presence of WT b-Arr1, CXCR4 localized with the TCR at the IS (Fig 7D), whereas expression of b-Arr1 (319- 418) induced the accumulation of both CXCR4 and the TCR in intracellular vesicles, preventing the accumulation of CXCR4 at the IS (Fig 7D)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jurkat)|taxid:9606(Homo sapiens) - 2014/04/28 2014/10/16 rogid:154Z++W8VsgmEd4rSCEVkw4xLgA10116 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 intact-crc:F3C0EAD7337A596E|rigid:cz23nbypAgNzr5MqmAQ0RkacxPI false flag tag:?-?|binding-associated region:319-418 mcherry fluorescent protein tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P20963 uniprotkb:P29066 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 intact:EBI-4303019|ensembl:ENSRNOP00000046069 psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:arrb1_rat(display_long)|uniprotkb:Arrb1(gene name)|psi-mi:Arrb1(display_short)|uniprotkb:Arrestin beta-1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9515078|imex:IM-23088-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N rgd:2156|refseq:NP_037042.1|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P29066|rcsb pdb:4JQI|rcsb pdb:6KL7|rcsb pdb:6U1N|reactome:R-RNO-418555|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-456926|reactome:R-RNO-5635838|reactome:R-RNO-5674135|reactome:R-RNO-5689880|reactome:R-RNO-8856825|reactome:R-RNO-8856828|interpro:IPR011021(Arrestin-like, N-terminal)|ensembl:ENSRNOG00000030404(gene)|ensembl:ENSRNOT00000043554(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019899"(enzyme binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|dip:DIP-40808N go:"GO:0001772"(immunological synapse) - - figure legend:f7d|comment:"We assessed the role of b-Arr1 in mediating CXCR4 translocation to the IS by analyzing Jurkat cells stimulated with superantigen- loaded APCs. In the presence of WT b-Arr1, CXCR4 localized with the TCR at the IS (Fig 7D), whereas expression of b-Arr1 (319- 418) induced the accumulation of both CXCR4 and the TCR in intracellular vesicles, preventing the accumulation of CXCR4 at the IS (Fig 7D)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jurkat)|taxid:9606(Homo sapiens) - 2014/04/28 2014/10/16 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 rogid:154Z++W8VsgmEd4rSCEVkw4xLgA10116 intact-crc:B3D7A04C9AB61E2C|rigid:cz23nbypAgNzr5MqmAQ0RkacxPI false mcherry fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P49407 uniprotkb:Q00610 intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581 intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00 psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym) psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fernández-Arenas et al. (2014) pubmed:24502978|imex:IM-23088 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9514981|imex:IM-23088-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004032.2|refseq:NP_064647.1|ensembl:ENSG00000137486(gene)|ensembl:ENST00000420843(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016573"(histone acetylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29979N ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424 go:"GO:0030139"(endocytic vesicle) - - figure legend:sf3 f3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jurkat)|taxid:9606(Homo sapiens) - 2014/04/28 2014/10/16 rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606 rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606 intact-crc:4888DE5FC472BEA4|rigid:xESihh8SnxI2lB9KKAtkoSMaCE4 false binding-associated region:319-418|green fluorescent protein tag:?-? - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0422"(immunostaining)