#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B chebi:"CHEBI:37397" uniprotkb:P61148 intact:EBI-9673920|chebi:"CHEBI:23224"|chebi:"CHEBI:3676" intact:EBI-9672367|uniprotkb:P10935|ensembl:ENSMUSP00000045710|ensembl:ENSMUSP00000111245|ensembl:ENSMUSP00000157968 psi-mi:chondroitin sulfate-1(display_short)|psi-mi:"CHEBI:37397"(display_long)|intact:chondroitin polysulfate(synonym)|intact:Chondroitin sulfate(synonym)|intact:chondroitin sulfates(synonym)|intact:chondroitin sulfuric acid(synonym)|intact:chondroitin sulphate(synonym)|intact:Chondroitinsulfat(synonym) psi-mi:fgf1_mouse(display_long)|uniprotkb:Fgf1(gene name)|psi-mi:Fgf1(display_short)|uniprotkb:Fgf-1(gene name synonym)|uniprotkb:Fgfa(gene name synonym)|uniprotkb:Acidic fibroblast growth factor(gene name synonym)|uniprotkb:Heparin-binding growth factor 1(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Nikolovska et al. (2014) pubmed:24447999|imex:IM-22964 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-9672423|imex:IM-22964-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:XP_011245144.1|refseq:XP_011245145.1|refseq:XP_017173319.1|refseq:NP_034327.1|refseq:XP_006525707.1|refseq:XP_006525708.1|refseq:XP_006525710.1|refseq:XP_006525711.1|refseq:XP_006525712.1|ensembl:ENSMUSG00000036585(gene)|ensembl:ENSMUST00000040647(transcript)|ensembl:ENSMUST00000115582(transcript)|ensembl:ENSMUST00000236630(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001525"(angiogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060681"(branch elongation involved in ureteric bud branching)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0072163"(mesonephric epithelium development)|go:"GO:1901509"(regulation of endothelial tube morphogenesis)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000544"(regulation of endothelial cell chemotaxis to fibroblast growth factor)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR028210|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190322|reactome:R-MMU-190370|reactome:R-MMU-190371|reactome:R-MMU-190372|reactome:R-MMU-190373|reactome:R-MMU-190375|reactome:R-MMU-190377|reactome:R-MMU-5654221|reactome:R-MMU-5654227|reactome:R-MMU-5654228|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654695|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654710|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5654720|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5673001|reactome:R-MMU-6811558|reactome:R-MMU-5654219 - comment:Experiment done with a mixture of chondroitin sulfate/dermatan sulfate. Both glycosaminoglycans have the same disaccharide composition but they differ by their iduronic acid level and their sulfation pattern. - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/07/17 2018/08/28 - rogid:ZOV+Utsn9XSOaEQ1WLoUCVZUpZ410090 intact-crc:C7E4EB3948889CA8 false - alkaline phosphatase tag:?-? - - psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) chebi:"CHEBI:37397" uniprotkb:P36363 intact:EBI-9673920|chebi:"CHEBI:23224"|chebi:"CHEBI:3676" intact:EBI-9672431|ensembl:ENSMUSP00000069681|ensembl:ENSMUSP00000106072 psi-mi:chondroitin sulfate-1(display_short)|psi-mi:"CHEBI:37397"(display_long)|intact:chondroitin polysulfate(synonym)|intact:Chondroitin sulfate(synonym)|intact:chondroitin sulfates(synonym)|intact:chondroitin sulfuric acid(synonym)|intact:chondroitin sulphate(synonym)|intact:Chondroitinsulfat(synonym) psi-mi:fgf7_mouse(display_long)|uniprotkb:Fgf7(gene name)|psi-mi:Fgf7(display_short)|uniprotkb:Fgf-7(gene name synonym)|uniprotkb:Kgf(gene name synonym)|uniprotkb:Heparin-binding growth factor 7(gene name synonym)|uniprotkb:Keratinocyte growth factor(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Nikolovska et al. (2014) pubmed:24447999|imex:IM-22964 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-9672429|imex:IM-22964-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_032034.1|ensembl:ENSMUSG00000027208(gene)|ensembl:ENSMUST00000064794(transcript)|ensembl:ENSMUST00000110442(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005111"(type 2 fibroblast growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010463"(mesenchymal cell proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042060"(wound healing)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061033"(secretion by lung epithelial cell involved in lung growth)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR028247|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190377|reactome:R-MMU-5654221|reactome:R-MMU-5654695|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654727|reactome:R-MMU-5673001|reactome:R-MMU-6811558 - comment:Experiment done with a mixture of chondroitin sulfate/dermatan sulfate. Both glycosaminoglycans have the same disaccharide composition but they differ by their iduronic acid level and their sulfation pattern. - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/07/17 2018/08/28 - rogid:HyWhKPIQCN4hNJILN7DLFEWf8pg10090 intact-crc:716154B58AEBDDDD false - alkaline phosphatase tag:?-? - - psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) chebi:"CHEBI:37397" uniprotkb:P37237 intact:EBI-9673920|chebi:"CHEBI:23224"|chebi:"CHEBI:3676" intact:EBI-9672476|ensembl:ENSMUSP00000026241 psi-mi:chondroitin sulfate-1(display_short)|psi-mi:"CHEBI:37397"(display_long)|intact:chondroitin polysulfate(synonym)|intact:Chondroitin sulfate(synonym)|intact:chondroitin sulfates(synonym)|intact:chondroitin sulfuric acid(synonym)|intact:chondroitin sulphate(synonym)|intact:Chondroitinsulfat(synonym) psi-mi:fgf8_mouse(display_long)|uniprotkb:Fgf8(gene name)|psi-mi:Fgf8(display_short)|uniprotkb:Aigf(gene name synonym)|uniprotkb:Androgen-induced growth factor(gene name synonym)|uniprotkb:Heparin-binding growth factor 8(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Nikolovska et al. (2014) pubmed:24447999|imex:IM-22964 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-9672568|imex:IM-22964-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001159834.1|refseq:NP_001159835.1|refseq:NP_034335.1|ensembl:ENSMUSG00000025219|dip:DIP-6030N|ensembl:ENSMUSG00000025219(gene)|ensembl:ENSMUST00000026241(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0001822"(kidney development)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005105"(type 1 fibroblast growth factor receptor binding)|go:"GO:0005111"(type 2 fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008406"(gonad development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021537"(telencephalon development)|go:"GO:0021543"(pallium development)|go:"GO:0021544"(subpallium development)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0030917"(midbrain-hindbrain boundary development)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048699"(generation of neurons)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0055026"(negative regulation of cardiac muscle tissue development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060128"(corticotropin hormone secreting cell differentiation)|go:"GO:0060129"(thyroid-stimulating hormone-secreting cell differentiation)|go:"GO:0060348"(bone development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090134"(cell migration involved in mesendoderm migration)|go:"GO:0120223"(larynx morphogenesis)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR028249|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190322|reactome:R-MMU-190371|reactome:R-MMU-190372|reactome:R-MMU-190373|reactome:R-MMU-190375|reactome:R-MMU-5654219|reactome:R-MMU-5654221|reactome:R-MMU-5654227|reactome:R-MMU-5654228|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654695|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654710|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5654720|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5658623|reactome:R-MMU-5673001|reactome:R-MMU-6811558 - comment:Experiment done with a mixture of chondroitin sulfate/dermatan sulfate. Both glycosaminoglycans have the same disaccharide composition but they differ by their iduronic acid level and their sulfation pattern. - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/07/17 2018/08/28 - rogid:VOor6hBeOpiAjk2tW1CLP/tOxis10090 intact-crc:8CE45121CC74C5D9 false - alkaline phosphatase tag:?-? - - psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) uniprotkb:P61148 uniprotkb:P07585 intact:EBI-9672367|uniprotkb:P10935|ensembl:ENSMUSP00000045710|ensembl:ENSMUSP00000111245|ensembl:ENSMUSP00000157968 intact:EBI-9663608|uniprotkb:Q9P0Z0|uniprotkb:Q9P0Z1|uniprotkb:Q9Y5N8|uniprotkb:Q9Y5N9|ensembl:ENSP00000052754|ensembl:ENSP00000447654 psi-mi:fgf1_mouse(display_long)|uniprotkb:Fgf1(gene name)|psi-mi:Fgf1(display_short)|uniprotkb:Fgf-1(gene name synonym)|uniprotkb:Fgfa(gene name synonym)|uniprotkb:Acidic fibroblast growth factor(gene name synonym)|uniprotkb:Heparin-binding growth factor 1(gene name synonym) psi-mi:pgs2_human(display_long)|uniprotkb:DCN(gene name)|psi-mi:DCN(display_short)|uniprotkb:SLRR1B(gene name synonym)|uniprotkb:Bone proteoglycan II(gene name synonym)|uniprotkb:PG-S2(gene name synonym)|uniprotkb:PG40(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Nikolovska et al. (2014) pubmed:24447999|imex:IM-22964 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-9672575|imex:IM-22964-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245144.1|refseq:XP_011245145.1|refseq:XP_017173319.1|refseq:NP_034327.1|refseq:XP_006525707.1|refseq:XP_006525708.1|refseq:XP_006525710.1|refseq:XP_006525711.1|refseq:XP_006525712.1|ensembl:ENSMUSG00000036585(gene)|ensembl:ENSMUST00000040647(transcript)|ensembl:ENSMUST00000115582(transcript)|ensembl:ENSMUST00000236630(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001525"(angiogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060681"(branch elongation involved in ureteric bud branching)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0072163"(mesonephric epithelium development)|go:"GO:1901509"(regulation of endothelial tube morphogenesis)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000544"(regulation of endothelial cell chemotaxis to fibroblast growth factor)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR028210|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190322|reactome:R-MMU-190370|reactome:R-MMU-190371|reactome:R-MMU-190372|reactome:R-MMU-190373|reactome:R-MMU-190375|reactome:R-MMU-190377|reactome:R-MMU-5654221|reactome:R-MMU-5654227|reactome:R-MMU-5654228|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654695|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654710|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5654720|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5673001|reactome:R-MMU-6811558|reactome:R-MMU-5654219 refseq:XP_016874406.1|refseq:NP_001911.1|refseq:NP_598010.1|refseq:NP_598011.1|refseq:NP_598012.1|refseq:NP_598013.1|refseq:NP_598014.1|refseq:XP_005268750.1|refseq:XP_006719333.1|ensembl:ENSG00000011465(gene)|ensembl:ENST00000052754(transcript)|ensembl:ENST00000552962(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001890"(placenta development)|go:"GO:0003723"(RNA binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005589"(collagen type VI trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007568"(aging)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019800"(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan)|go:"GO:0030021"(extracellular matrix structural constituent conferring compression resistance)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR016352(Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan)|interpro:IPR028549|interpro:IPR032675|reactome:R-HSA-1474228|reactome:R-HSA-1971475|reactome:R-HSA-2022870|reactome:R-HSA-2022923|reactome:R-HSA-2024101|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3595172|reactome:R-HSA-3595174|reactome:R-HSA-3595177|reactome:R-HSA-4420332|go:"GO:0042060"(wound healing) - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/07/17 2014/10/16 rogid:ZOV+Utsn9XSOaEQ1WLoUCVZUpZ410090 rogid:0QACJEISdDItcqJBJtaLNCvleeg9606 intact-crc:0A60BFFF617872D3|rigid:jBBSSi9sSsadbTPauWnqH4Th0Lo false alkaline phosphatase tag:?-? dermatan 4-sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine:?-?|chondroitin sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine:?-? - - psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) uniprotkb:P36363 uniprotkb:P07585 intact:EBI-9672431|ensembl:ENSMUSP00000069681|ensembl:ENSMUSP00000106072 intact:EBI-9663608|uniprotkb:Q9P0Z0|uniprotkb:Q9P0Z1|uniprotkb:Q9Y5N8|uniprotkb:Q9Y5N9|ensembl:ENSP00000052754|ensembl:ENSP00000447654 psi-mi:fgf7_mouse(display_long)|uniprotkb:Fgf7(gene name)|psi-mi:Fgf7(display_short)|uniprotkb:Fgf-7(gene name synonym)|uniprotkb:Kgf(gene name synonym)|uniprotkb:Heparin-binding growth factor 7(gene name synonym)|uniprotkb:Keratinocyte growth factor(gene name synonym) psi-mi:pgs2_human(display_long)|uniprotkb:DCN(gene name)|psi-mi:DCN(display_short)|uniprotkb:SLRR1B(gene name synonym)|uniprotkb:Bone proteoglycan II(gene name synonym)|uniprotkb:PG-S2(gene name synonym)|uniprotkb:PG40(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Nikolovska et al. (2014) pubmed:24447999|imex:IM-22964 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-9672581|imex:IM-22964-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032034.1|ensembl:ENSMUSG00000027208(gene)|ensembl:ENSMUST00000064794(transcript)|ensembl:ENSMUST00000110442(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005111"(type 2 fibroblast growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010463"(mesenchymal cell proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042060"(wound healing)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061033"(secretion by lung epithelial cell involved in lung growth)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR028247|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190377|reactome:R-MMU-5654221|reactome:R-MMU-5654695|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654727|reactome:R-MMU-5673001|reactome:R-MMU-6811558 refseq:XP_016874406.1|refseq:NP_001911.1|refseq:NP_598010.1|refseq:NP_598011.1|refseq:NP_598012.1|refseq:NP_598013.1|refseq:NP_598014.1|refseq:XP_005268750.1|refseq:XP_006719333.1|ensembl:ENSG00000011465(gene)|ensembl:ENST00000052754(transcript)|ensembl:ENST00000552962(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001890"(placenta development)|go:"GO:0003723"(RNA binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005589"(collagen type VI trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007568"(aging)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019800"(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan)|go:"GO:0030021"(extracellular matrix structural constituent conferring compression resistance)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR016352(Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan)|interpro:IPR028549|interpro:IPR032675|reactome:R-HSA-1474228|reactome:R-HSA-1971475|reactome:R-HSA-2022870|reactome:R-HSA-2022923|reactome:R-HSA-2024101|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3595172|reactome:R-HSA-3595174|reactome:R-HSA-3595177|reactome:R-HSA-4420332|go:"GO:0042060"(wound healing) - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/07/17 2014/10/16 rogid:HyWhKPIQCN4hNJILN7DLFEWf8pg10090 rogid:0QACJEISdDItcqJBJtaLNCvleeg9606 intact-crc:7995C8004221E0B3|rigid:Qm6PjLbXSLehLgR0h1gyQIlhyAQ false alkaline phosphatase tag:?-? chondroitin sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine:?-?|dermatan 4-sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine:?-? - - psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) uniprotkb:P37237 uniprotkb:P07585 intact:EBI-9672476|ensembl:ENSMUSP00000026241 intact:EBI-9663608|uniprotkb:Q9P0Z0|uniprotkb:Q9P0Z1|uniprotkb:Q9Y5N8|uniprotkb:Q9Y5N9|ensembl:ENSP00000052754|ensembl:ENSP00000447654 psi-mi:fgf8_mouse(display_long)|uniprotkb:Fgf8(gene name)|psi-mi:Fgf8(display_short)|uniprotkb:Aigf(gene name synonym)|uniprotkb:Androgen-induced growth factor(gene name synonym)|uniprotkb:Heparin-binding growth factor 8(gene name synonym) psi-mi:pgs2_human(display_long)|uniprotkb:DCN(gene name)|psi-mi:DCN(display_short)|uniprotkb:SLRR1B(gene name synonym)|uniprotkb:Bone proteoglycan II(gene name synonym)|uniprotkb:PG-S2(gene name synonym)|uniprotkb:PG40(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Nikolovska et al. (2014) pubmed:24447999|imex:IM-22964 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-9672587|imex:IM-22964-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159834.1|refseq:NP_001159835.1|refseq:NP_034335.1|ensembl:ENSMUSG00000025219|dip:DIP-6030N|ensembl:ENSMUSG00000025219(gene)|ensembl:ENSMUST00000026241(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0001822"(kidney development)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005105"(type 1 fibroblast growth factor receptor binding)|go:"GO:0005111"(type 2 fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008406"(gonad development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021537"(telencephalon development)|go:"GO:0021543"(pallium development)|go:"GO:0021544"(subpallium development)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0030917"(midbrain-hindbrain boundary development)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048699"(generation of neurons)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0055026"(negative regulation of cardiac muscle tissue development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060128"(corticotropin hormone secreting cell differentiation)|go:"GO:0060129"(thyroid-stimulating hormone-secreting cell differentiation)|go:"GO:0060348"(bone development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090134"(cell migration involved in mesendoderm migration)|go:"GO:0120223"(larynx morphogenesis)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR028249|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190322|reactome:R-MMU-190371|reactome:R-MMU-190372|reactome:R-MMU-190373|reactome:R-MMU-190375|reactome:R-MMU-5654219|reactome:R-MMU-5654221|reactome:R-MMU-5654227|reactome:R-MMU-5654228|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654695|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654710|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5654720|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5658623|reactome:R-MMU-5673001|reactome:R-MMU-6811558 refseq:XP_016874406.1|refseq:NP_001911.1|refseq:NP_598010.1|refseq:NP_598011.1|refseq:NP_598012.1|refseq:NP_598013.1|refseq:NP_598014.1|refseq:XP_005268750.1|refseq:XP_006719333.1|ensembl:ENSG00000011465(gene)|ensembl:ENST00000052754(transcript)|ensembl:ENST00000552962(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001890"(placenta development)|go:"GO:0003723"(RNA binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005589"(collagen type VI trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007568"(aging)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019800"(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan)|go:"GO:0030021"(extracellular matrix structural constituent conferring compression resistance)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR016352(Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan)|interpro:IPR028549|interpro:IPR032675|reactome:R-HSA-1474228|reactome:R-HSA-1971475|reactome:R-HSA-2022870|reactome:R-HSA-2022923|reactome:R-HSA-2024101|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3595172|reactome:R-HSA-3595174|reactome:R-HSA-3595177|reactome:R-HSA-4420332|go:"GO:0042060"(wound healing) - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/07/17 2014/10/16 rogid:VOor6hBeOpiAjk2tW1CLP/tOxis10090 rogid:0QACJEISdDItcqJBJtaLNCvleeg9606 intact-crc:CE2BAF9057C22115|rigid:lLyFJzCOqhG+C8T4Cyxj0Cy8s18 false alkaline phosphatase tag:?-? chondroitin sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine:?-?|dermatan 4-sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine:?-? - - psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) uniprotkb:P09038 uniprotkb:P07585 intact:EBI-977447|ensembl:ENSP00000264498|uniprotkb:A4LBB8|uniprotkb:O00527|uniprotkb:P78443|uniprotkb:Q16443|uniprotkb:Q5PY50|uniprotkb:Q7KZ11|uniprotkb:Q7KZ72|uniprotkb:Q9UC54|uniprotkb:Q9UCS5|uniprotkb:Q9UCS6 intact:EBI-9663608|uniprotkb:Q9P0Z0|uniprotkb:Q9P0Z1|uniprotkb:Q9Y5N8|uniprotkb:Q9Y5N9|ensembl:ENSP00000052754|ensembl:ENSP00000447654 psi-mi:fgf2_human(display_long)|uniprotkb:Basic fibroblast growth factor(gene name synonym)|uniprotkb:FGF2(gene name)|psi-mi:FGF2(display_short)|uniprotkb:FGFB(gene name synonym)|uniprotkb:Heparin-binding growth factor 2(gene name synonym) psi-mi:pgs2_human(display_long)|uniprotkb:DCN(gene name)|psi-mi:DCN(display_short)|uniprotkb:SLRR1B(gene name synonym)|uniprotkb:Bone proteoglycan II(gene name synonym)|uniprotkb:PG-S2(gene name synonym)|uniprotkb:PG40(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Nikolovska et al. (2014) pubmed:24447999|imex:IM-22964 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-9672614|imex:IM-22964-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001997.5|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046668"(regulation of retinal cell programmed cell death)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048678"(response to axon injury)|go:"GO:0048864"(stem cell development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060128"(corticotropin hormone secreting cell differentiation)|go:"GO:0060129"(thyroid-stimulating hormone-secreting cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|ensembl:ENSG00000138685(gene)|ensembl:ENST00000264498(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0019956"(chemokine binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0021940"(positive regulation of cerebellar granule cell precursor proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030214"(hyaluronan catabolic process)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0038001"(paracrine signaling)|go:"GO:0014843"(growth factor dependent regulation of skeletal muscle satellite cell proliferation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042060"(wound healing)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|reactome:R-HSA-5654733|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5658623|reactome:R-HSA-5673001|reactome:R-HSA-5654732|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851708|reactome:R-HSA-8853338|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090049"(regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090722"(receptor-receptor interaction)|go:"GO:1902748"(positive regulation of lens fiber cell differentiation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903587"(regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905278"(positive regulation of epithelial tube formation)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000544"(regulation of endothelial cell chemotaxis to fibroblast growth factor)|go:"GO:2000546"(positive regulation of endothelial cell chemotaxis to fibroblast growth factor)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR028223|rcsb pdb:1BAS|rcsb pdb:1BFB|rcsb pdb:1BFC|go:"GO:0061045"(negative regulation of wound healing)|rcsb pdb:1BFG|rcsb pdb:1BLA|rcsb pdb:1BLD|rcsb pdb:1CVS|rcsb pdb:1EV2|rcsb pdb:1FGA|rcsb pdb:1FQ9|rcsb pdb:1II4|rcsb pdb:1IIL|rcsb pdb:2BFH|rcsb pdb:2FGF|rcsb pdb:2M49|rcsb pdb:4FGF|rcsb pdb:4OEE|rcsb pdb:4OEF|rcsb pdb:4OEG|rcsb pdb:1BFF|rcsb pdb:5X1O|rcsb pdb:6L4O|reactome:R-HSA-109704|reactome:R-HSA-1257604|reactome:R-HSA-1839122|reactome:R-HSA-1839130|reactome:R-HSA-190370|reactome:R-HSA-190372|reactome:R-HSA-190373|reactome:R-HSA-190375|reactome:R-HSA-190377|reactome:R-HSA-2033514|reactome:R-HSA-2033519|reactome:R-HSA-2219530|reactome:R-HSA-2892247|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-5654219|reactome:R-HSA-5654221|reactome:R-HSA-5654227|reactome:R-HSA-5654228|reactome:R-HSA-5654687|reactome:R-HSA-5654688|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5654720|reactome:R-HSA-190322|reactome:R-HSA-5654726|reactome:R-HSA-5654727|dip:DIP-4012N refseq:XP_016874406.1|refseq:NP_001911.1|refseq:NP_598010.1|refseq:NP_598011.1|refseq:NP_598012.1|refseq:NP_598013.1|refseq:NP_598014.1|refseq:XP_005268750.1|refseq:XP_006719333.1|ensembl:ENSG00000011465(gene)|ensembl:ENST00000052754(transcript)|ensembl:ENST00000552962(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001890"(placenta development)|go:"GO:0003723"(RNA binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005589"(collagen type VI trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007568"(aging)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019800"(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan)|go:"GO:0030021"(extracellular matrix structural constituent conferring compression resistance)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR016352(Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan)|interpro:IPR028549|interpro:IPR032675|reactome:R-HSA-1474228|reactome:R-HSA-1971475|reactome:R-HSA-2022870|reactome:R-HSA-2022923|reactome:R-HSA-2024101|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3595172|reactome:R-HSA-3595174|reactome:R-HSA-3595177|reactome:R-HSA-4420332|go:"GO:0042060"(wound healing) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/07/17 2014/10/16 rogid:udCxjwNH9EeWxJlw1QnhGVzRUko9606 rogid:0QACJEISdDItcqJBJtaLNCvleeg9606 intact-crc:1BF484A2AFD69B98|rigid:ticlX4/h5q9jcjkJW3UgZewV0h8 false tag:?-? chondroitin sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine:?-?|dermatan 4-sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine:?-? - - psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) chebi:"CHEBI:37397" uniprotkb:P09038 intact:EBI-9673920|chebi:"CHEBI:23224"|chebi:"CHEBI:3676" intact:EBI-977447|ensembl:ENSP00000264498|uniprotkb:A4LBB8|uniprotkb:O00527|uniprotkb:P78443|uniprotkb:Q16443|uniprotkb:Q5PY50|uniprotkb:Q7KZ11|uniprotkb:Q7KZ72|uniprotkb:Q9UC54|uniprotkb:Q9UCS5|uniprotkb:Q9UCS6 psi-mi:chondroitin sulfate-1(display_short)|psi-mi:"CHEBI:37397"(display_long)|intact:chondroitin polysulfate(synonym)|intact:Chondroitin sulfate(synonym)|intact:chondroitin sulfates(synonym)|intact:chondroitin sulfuric acid(synonym)|intact:chondroitin sulphate(synonym)|intact:Chondroitinsulfat(synonym) psi-mi:fgf2_human(display_long)|uniprotkb:Basic fibroblast growth factor(gene name synonym)|uniprotkb:FGF2(gene name)|psi-mi:FGF2(display_short)|uniprotkb:FGFB(gene name synonym)|uniprotkb:Heparin-binding growth factor 2(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Nikolovska et al. (2014) pubmed:24447999|imex:IM-22964 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-9672624|imex:IM-22964-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001997.5|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046668"(regulation of retinal cell programmed cell death)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048678"(response to axon injury)|go:"GO:0048864"(stem cell development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060128"(corticotropin hormone secreting cell differentiation)|go:"GO:0060129"(thyroid-stimulating hormone-secreting cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|ensembl:ENSG00000138685(gene)|ensembl:ENST00000264498(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0019956"(chemokine binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0021940"(positive regulation of cerebellar granule cell precursor proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030214"(hyaluronan catabolic process)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0038001"(paracrine signaling)|go:"GO:0014843"(growth factor dependent regulation of skeletal muscle satellite cell proliferation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042060"(wound healing)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|reactome:R-HSA-5654733|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5658623|reactome:R-HSA-5673001|reactome:R-HSA-5654732|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851708|reactome:R-HSA-8853338|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090049"(regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090722"(receptor-receptor interaction)|go:"GO:1902748"(positive regulation of lens fiber cell differentiation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903587"(regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905278"(positive regulation of epithelial tube formation)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000544"(regulation of endothelial cell chemotaxis to fibroblast growth factor)|go:"GO:2000546"(positive regulation of endothelial cell chemotaxis to fibroblast growth factor)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR028223|rcsb pdb:1BAS|rcsb pdb:1BFB|rcsb pdb:1BFC|go:"GO:0061045"(negative regulation of wound healing)|rcsb pdb:1BFG|rcsb pdb:1BLA|rcsb pdb:1BLD|rcsb pdb:1CVS|rcsb pdb:1EV2|rcsb pdb:1FGA|rcsb pdb:1FQ9|rcsb pdb:1II4|rcsb pdb:1IIL|rcsb pdb:2BFH|rcsb pdb:2FGF|rcsb pdb:2M49|rcsb pdb:4FGF|rcsb pdb:4OEE|rcsb pdb:4OEF|rcsb pdb:4OEG|rcsb pdb:1BFF|rcsb pdb:5X1O|rcsb pdb:6L4O|reactome:R-HSA-109704|reactome:R-HSA-1257604|reactome:R-HSA-1839122|reactome:R-HSA-1839130|reactome:R-HSA-190370|reactome:R-HSA-190372|reactome:R-HSA-190373|reactome:R-HSA-190375|reactome:R-HSA-190377|reactome:R-HSA-2033514|reactome:R-HSA-2033519|reactome:R-HSA-2219530|reactome:R-HSA-2892247|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-5654219|reactome:R-HSA-5654221|reactome:R-HSA-5654227|reactome:R-HSA-5654228|reactome:R-HSA-5654687|reactome:R-HSA-5654688|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5654720|reactome:R-HSA-190322|reactome:R-HSA-5654726|reactome:R-HSA-5654727|dip:DIP-4012N - comment:Experiment done with a mixture of chondroitin sulfate/dermatan sulfate. Both glycosaminoglycans have the same disaccharide composition but they differ by their iduronic acid level and their sulfation pattern. - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/07/17 2018/08/28 - rogid:udCxjwNH9EeWxJlw1QnhGVzRUko9606 intact-crc:CA3033C3D5260D42 false - tag:?-? - - psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity) psi-mi:"MI:1323"(tag visualisation by alkaline phosphatase activity)