#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P07845	uniprotkb:P07845	intact:EBI-9084009	intact:EBI-9084009	psi-mi:actp2_stihl(display_long)|uniprotkb:Cytolysin III(gene name synonym)|uniprotkb:Sticholysin II(gene name synonym)|uniprotkb:Sticholysin-2(gene name synonym)	psi-mi:actp2_stihl(display_long)|uniprotkb:Cytolysin III(gene name synonym)|uniprotkb:Sticholysin II(gene name synonym)|uniprotkb:Sticholysin-2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	García-Linares et al. (2014)	pubmed:24418371|imex:IM-22076	taxid:6123(stohe)|taxid:6123(Stoichactis helianthus)	taxid:6123(stohe)|taxid:6123(Stoichactis helianthus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9084034|imex:IM-22076-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009104(Sea anemone cytolysin)|interpro:IPR015926(Cytolysin/lectin)|rcsb pdb:1GWY|rcsb pdb:1O71|rcsb pdb:1O72|rcsb pdb:2L2B|rcsb pdb:2L38|go:"GO:0005576"(extracellular region)|go:"GO:0006812"(cation transport)|go:"GO:0015267"(channel activity)|go:"GO:0042151"(nematocyst)|go:"GO:0042802"(identical protein binding)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0052331"(obsolete hemolysis in other organism involved in symbiotic interaction)|go:"GO:0090729"(toxin activity)	interpro:IPR009104(Sea anemone cytolysin)|interpro:IPR015926(Cytolysin/lectin)|rcsb pdb:1GWY|rcsb pdb:1O71|rcsb pdb:1O72|rcsb pdb:2L2B|rcsb pdb:2L38|go:"GO:0005576"(extracellular region)|go:"GO:0006812"(cation transport)|go:"GO:0015267"(channel activity)|go:"GO:0042151"(nematocyst)|go:"GO:0042802"(identical protein binding)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0052331"(obsolete hemolysis in other organism involved in symbiotic interaction)|go:"GO:0090729"(toxin activity)	-	comment:"RAD mutant (G142A)"	comment:"RAD mutant (G142A)"	figure legend:f3|comment:"Sedimentation velocity (560 μM protein concentration in water)  experiments were conducted (Fig. 3). The sedimentation coefficients obtained  for the StnII RAD mutant in these conditions indicated the presence of different  species into the sample: monomer (s20,w= 2.2 S, 56%), dimer (s20,w= 3.1 S,  42%,) and tetramer (s20,w= 5.25 S, 2%), suggesting an aggregating prone  behaviour of this mutant in solution. Not surprisingly, equilibrium sedimentation  analysis of this same sample after an almost 40-fold dilution (15 μM protein  concentration) yielded results compatible with only a single monomer species  (Fig. 3) with an average molecular mass (MWapp) of 20.7 ± 0.7 kDa (average of  all velocities assayed)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/14	2014/10/16	rogid:LGv2tf/GtUPqnWLrO47q8jtPkCg6123	rogid:LGv2tf/GtUPqnWLrO47q8jtPkCg6123	intact-crc:46A2A6D9A4507B7C|rigid:bMjDGv9czVAb/vgkWZM2KQtDtIY	false	-	-	4	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07845	uniprotkb:P07845	intact:EBI-9084009	intact:EBI-9084009	psi-mi:actp2_stihl(display_long)|uniprotkb:Cytolysin III(gene name synonym)|uniprotkb:Sticholysin II(gene name synonym)|uniprotkb:Sticholysin-2(gene name synonym)	psi-mi:actp2_stihl(display_long)|uniprotkb:Cytolysin III(gene name synonym)|uniprotkb:Sticholysin II(gene name synonym)|uniprotkb:Sticholysin-2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	García-Linares et al. (2014)	pubmed:24418371|imex:IM-22076	taxid:6123(stohe)|taxid:6123(Stoichactis helianthus)	taxid:6123(stohe)|taxid:6123(Stoichactis helianthus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9084000|imex:IM-22076-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009104(Sea anemone cytolysin)|interpro:IPR015926(Cytolysin/lectin)|rcsb pdb:1GWY|rcsb pdb:1O71|rcsb pdb:1O72|rcsb pdb:2L2B|rcsb pdb:2L38|go:"GO:0005576"(extracellular region)|go:"GO:0006812"(cation transport)|go:"GO:0015267"(channel activity)|go:"GO:0042151"(nematocyst)|go:"GO:0042802"(identical protein binding)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0052331"(obsolete hemolysis in other organism involved in symbiotic interaction)|go:"GO:0090729"(toxin activity)	interpro:IPR009104(Sea anemone cytolysin)|interpro:IPR015926(Cytolysin/lectin)|rcsb pdb:1GWY|rcsb pdb:1O71|rcsb pdb:1O72|rcsb pdb:2L2B|rcsb pdb:2L38|go:"GO:0005576"(extracellular region)|go:"GO:0006812"(cation transport)|go:"GO:0015267"(channel activity)|go:"GO:0042151"(nematocyst)|go:"GO:0042802"(identical protein binding)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0052331"(obsolete hemolysis in other organism involved in symbiotic interaction)|go:"GO:0090729"(toxin activity)	-	comment:"RAD mutant (G142A)"	comment:"RAD mutant (G142A)"	figure legend:f3|comment:"Sedimentation velocity (560 μM protein concentration in water)  experiments were conducted (Fig. 3). The sedimentation coefficients obtained  for the StnII RAD mutant in these conditions indicated the presence of different  species into the sample: monomer (s20,w= 2.2 S, 56%), dimer (s20,w= 3.1 S,  42%,) and tetramer (s20,w= 5.25 S, 2%), suggesting an aggregating prone  behaviour of this mutant in solution. Not surprisingly, equilibrium sedimentation  analysis of this same sample after an almost 40-fold dilution (15 μM protein  concentration) yielded results compatible with only a single monomer species  (Fig. 3) with an average molecular mass (MWapp) of 20.7 ± 0.7 kDa (average of  all velocities assayed)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/14	2014/10/16	rogid:LGv2tf/GtUPqnWLrO47q8jtPkCg6123	rogid:LGv2tf/GtUPqnWLrO47q8jtPkCg6123	intact-crc:834C6AB0D34D613C|rigid:bMjDGv9czVAb/vgkWZM2KQtDtIY	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)