#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O44382 uniprotkb:Q8INB9 intact:EBI-869364 intact:EBI-162210|uniprotkb:Q0KI65|uniprotkb:Q24293|uniprotkb:Q24469|uniprotkb:Q24470|uniprotkb:Q7JN11|uniprotkb:Q8T9A5|uniprotkb:Q9VEY7|ensemblmetazoa:FBpp0082682 psi-mi:o44382_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:slimb(gene name synonym)|uniprotkb:CG3412(orf name) psi-mi:akt1_drome(display_long)|uniprotkb:Akt1(gene name)|psi-mi:Akt1(display_short)|uniprotkb:CG4006(orf name)|uniprotkb:Akt(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2014) pubmed:24413555|imex:IM-22240 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9250805|imex:IM-22240-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283468|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-432524 refseq:NP_732113.3|refseq:NP_732114.1|refseq:NP_732115.1|flybase:FBgn0010379|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0090278"(negative regulation of peptide hormone secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR039026|reactome:R-DME-110478|reactome:R-DME-110523|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-1474151|reactome:R-DME-165158|reactome:R-DME-165159|reactome:R-DME-165181|reactome:R-DME-198323|reactome:R-DME-198693|reactome:R-DME-199418|reactome:R-DME-203615|reactome:R-DME-211163|reactome:R-DME-3769402|reactome:R-DME-389357|reactome:R-DME-389513|reactome:R-DME-392451|reactome:R-DME-450385|reactome:R-DME-450604|reactome:R-DME-5218920|reactome:R-DME-5628897|reactome:R-DME-6804759|reactome:R-DME-6811558|reactome:R-DME-69202|reactome:R-DME-69656|reactome:R-DME-8876198|reactome:R-DME-8948751|reactome:R-DME-9009391|reactome:R-DME-9604323|reactome:R-DME-9607240|reactome:R-DME-9614399|reactome:R-DME-9634638|ensemblmetazoa:FBgn0010379(gene)|ensemblmetazoa:FBtr0083228(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|refseq:NP_001287353.1|refseq:NP_001287354.1|dip:DIP-49060N - - - figure legend:f5n|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2014/03/03 2014/10/16 rogid:hKsZL6X4sxi/Zu4RDHlAV5IoZ2o7227 rogid:O+TwU/5zv00wpwqXLxtrJrHk3lw7227 intact-crc:88AB7198074FC624|rigid:p8b8Ng27MtRAmnDOCfx1NnMmUsc false flag tag:?-? myc tag:?-?|sufficient binding region:131-442 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)